CN211689103U - Embryo culture dish with automatic liquid changing function - Google Patents

Embryo culture dish with automatic liquid changing function Download PDF

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Publication number
CN211689103U
CN211689103U CN202020139430.2U CN202020139430U CN211689103U CN 211689103 U CN211689103 U CN 211689103U CN 202020139430 U CN202020139430 U CN 202020139430U CN 211689103 U CN211689103 U CN 211689103U
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sleeve
clamp
liquid
culture dish
container
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CN202020139430.2U
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Chinese (zh)
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王珊珊
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Nanjing Drum Tower Hospital
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Nanjing Drum Tower Hospital
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Abstract

The utility model belongs to the technical field of medical appliances, and discloses an embryo culture dish with automatic liquid changing function, wherein the front surfaces of a first sleeve, a second sleeve and a third sleeve are respectively embedded with a first adjusting locking wheel, a second adjusting locking wheel and a third adjusting locking wheel which are connected with the first sleeve, the second sleeve and the third sleeve through screw threads, the outer sides of the first sleeve, the second sleeve and the third sleeve are respectively and fixedly connected with a container clamp, a culture dish clamp and a bottle clamp, a liquid feeding component is arranged inside the container clamp, a dish body is arranged inside the culture dish clamp, a waste liquid collecting bottle is fixedly connected inside the bottle clamp, the utility model can inject quantitative fresh culture liquid into the dish body through the liquid feeding component, and the waste liquid in the dish body can be regularly changed through continuously dropping in the fresh culture liquid, thereby providing guarantee for the embryo development in the dish body, and in addition, the height of the dish body on a support column can be adjusted, the application requirements of different heights are met, and the application range is widened.

Description

Embryo culture dish with automatic liquid changing function
Technical Field
The utility model belongs to the technical field of medical instrument, specifically speaking relates to an embryo culture ware with automatic liquid function of trading.
Background
In vitro culture is a key link in the technology of In Vitro Fertilization Embryo Transfer (IVFET), and the external environment of embryo growth directly influences the growth and development of early embryos, thereby influencing the success rate of embryo planting. In vitro culture of embryos is a complex process that imposes stringent requirements on many factors in the growth environment, such as air quality, temperature, culture medium composition and pH and light. Whether the test-tube infant succeeds or not depends on whether a stable culture system can be provided or not to a great extent, and when a stable culture environment exists, the embryo can grow healthily and relatively improve the availability of the embryo. In this stable system, the embryo culture fluid plays a very important role because it provides nutrients required for the development of the embryo during its division. The embryo culture solution is rich in various amino acids required for embryo development, but the physiology and metabolism of the embryo are continuously changed during the culture process, and ammonia generated by amino acid decomposition and embryo metabolism has toxic effect on the embryo, so that the embryo culture solution needs to be continuously provided and waste liquid needs to be replaced at the same time.
At present, no special method is available for replacing the embryo culture solution, the culture solution is simply sucked by an artificial liquid sucker, the efficiency is low, the height of a culture dish is not adjustable, and the practicability is poor.
The utility model discloses the content
The utility model provides an embryo culture dish with automatically, trade liquid function has solved the problem of proposing among the above-mentioned background art.
In order to achieve the above object, the utility model adopts the following technical scheme:
an embryo culture dish with an automatic liquid changing function comprises a base and a pillar fixedly connected on the base, wherein a controller is fixedly connected to the outer side of the base, a storage battery is fixedly connected to the rear surface of the base, a waste liquid collecting bottle is further arranged on the upper surface of the base close to the outer side of the pillar, a water pump is further fixedly connected to the upper surface of the base close to the outer side of the pillar, a first sleeve, a second sleeve and a third sleeve are sequentially sleeved on the outer portion of the pillar in a sliding mode from top to bottom, a first adjusting locking wheel, a second adjusting locking wheel and a third adjusting locking wheel which are in threaded connection with the first sleeve, the second sleeve and the third sleeve are respectively embedded and installed on the front surfaces of the first sleeve, the second sleeve and the third sleeve, a container clamp, a culture dish clamp and a bottle clamp are fixedly connected to the outer sides of the first sleeve, the second sleeve and the third sleeve respectively, a liquid feeding assembly is arranged inside the container clamp, and a dish body is, the inside rigid coupling of bottle clamp has the waste liquid collecting bottle, the upper surface threaded connection of ware body has the bottle plug.
Furthermore, the water inlet end of the water pump is connected with the bottom of the dish body through a pipeline, and the water outlet end of the water pump is connected with the upper surface of the waste liquid collecting bottle through a pipeline.
Furthermore, the first sleeve, the second sleeve and the third sleeve are equal in size, and the first sleeve, the second sleeve and the third sleeve are all members made of stainless steel.
Further, send liquid subassembly to include handle, threaded rod, notes liquid mouth, piston, fresh culture solution container and liquid outlet, the outside rigid coupling of fresh culture solution container has notes liquid mouth, and the upper surface embedding of fresh culture solution container installs the threaded rod that passes through threaded connection rather than self, the lower surface center department rigid coupling of fresh culture solution container has the liquid outlet, and the inner wall laminating of fresh culture solution container has the piston, the top welding of threaded rod has the handle.
Furthermore, the container clamp is fixedly sleeved outside the fresh culture solution container, the container clamp and the fresh culture solution container are both made of transparent materials, and the front surface of the fresh culture solution container is also provided with scale marks.
Further, the piston is a rubber component, the upper surface of the piston and the bottom end of the threaded rod rotate through a bearing, the piston is of a disc-shaped structure, and the piston is a rubber component.
Further, the bottle clamp, the culture dish clamp and the container clamp are all of circular ring structures, and the bottle clamp, the culture dish clamp and the container clamp are all components made of alloy steel.
Further, the liquid outlet is connected with the dish body through a pipeline, and a valve is embedded in the liquid outlet.
The utility model discloses owing to adopted foretell structure, it compares with prior art, and the technical progress who gains lies in: the utility model discloses a send the liquid subassembly can be to the internal fresh culture solution of injection ration of ware, through constantly instiling into fresh culture solution, can carry out periodic replacement with the internal waste liquid of ware, for the internal embryo development of ware provides the guarantee, in addition, the height-adjustable of ware body on the pillar to adapt to the not application requirement of co-altitude, application scope has obtained the promotion.
Drawings
The accompanying drawings are included to provide a further understanding of the invention, and are incorporated in and constitute a part of this specification, illustrate embodiments of the invention, and together with the description serve to explain the invention and not to limit the invention.
In the drawings:
fig. 1 is a schematic structural diagram of an embodiment of the present invention;
FIG. 2 is a schematic structural view of a liquid feeding assembly according to an embodiment of the present invention;
fig. 3 is a schematic structural view of the bottle stopper in the embodiment of the present invention;
fig. 4 is a schematic structural view of a first adjusting locking wheel in the embodiment of the present invention;
labeling components: 1-pillar, 2-first sleeve, 3-first adjusting locking wheel, 4-second sleeve, 5-second adjusting locking wheel, 6-third sleeve, 7-third adjusting locking wheel, 8-waste liquid collecting bottle, 9-bottle clamp, 10-water pump, 11-base, 12-controller, 13-culture dish clamp, 14-dish body, 15-bottle stopper, 16-container clamp, 17-liquid feeding component, 18-handle, 19-threaded rod, 20-liquid injection port, 21-piston, 22-fresh culture liquid container, 23-liquid outlet.
Detailed Description
The preferred embodiments of the present invention will be described below with reference to the accompanying drawings. It should be understood that the preferred embodiments described herein are for purposes of illustration and explanation only and are not intended to limit the invention.
Embodiment one kind has embryo culture dish of the automatic liquid changing function
The embodiment discloses an embryo culture dish with automatic liquid changing function, including base 11 and pillar 1 of rigid coupling on base 11, base 11's the outside still rigid coupling has controller 12, and base 11's rear surface rigid coupling has the battery, base 11's upper surface is close to the pillar 1 outside and still is provided with waste liquid receiving flask 8, and base 11's upper surface is close to the pillar 1 outside still rigid coupling has water pump 10, water pump 10's the end of intaking links to each other through the pipeline with the bottom of the ware body 14, and the play water end of water pump 10 links to each other through the pipeline with the upper surface of waste liquid receiving flask 8, pillar 1's outside from top to bottom slides in proper order and is cup jointed first sleeve 2, second sleeve 4 and third sleeve 6, first sleeve 2, second sleeve 4 and third sleeve 6 are the same in size, and first sleeve 2, second sleeve 4 and third sleeve 6 are the component of stainless steel material, first sleeve 2, second sleeve 4, third sleeve 6, The embedding is installed respectively on the front surface of second sleeve 4 and third sleeve 6 and is passed through threaded connection's first regulation locking wheel 3 rather than oneself, locking wheel 5 is adjusted to the second and locking wheel 7 is adjusted to the third, and first sleeve 2, the outside of second sleeve 4 and third sleeve 6 rigid coupling respectively has the container to press from both sides 16, culture dish clamp 13 and bottle clamp 9, the bottle presss from both sides 9, culture dish clamp 13 and container clamp 16 are the loop configuration, and the bottle presss from both sides 9, culture dish clamp 13 and container clamp 16 are the component of alloy steel material, the inside of culture dish clamp 13 is provided with the ware body 14, the inside rigid coupling of bottle clamp 9 has waste liquid collecting bottle 8, the upper surface threaded connection of ware body 14 has bottle plug 15.
The container clamp 16 is internally provided with a liquid feeding assembly 17, the liquid feeding assembly 17 comprises a handle 18, a threaded rod 19, a liquid injection port 20, a piston 21, a fresh culture solution container 22 and a liquid outlet 23, the outer side of the fresh culture solution container 22 is fixedly connected with the liquid injection port 20, the upper surface of the fresh culture solution container 22 is embedded and provided with the threaded rod 19 in threaded connection with the fresh culture solution container 22, the lower surface center of the fresh culture solution container 22 is fixedly connected with the liquid outlet 23, the inner wall of the fresh culture solution container 22 is attached with the piston 21, the handle 18 is welded at the top end of the threaded rod 19, the container clamp 16 is fixedly sleeved outside the fresh culture solution container 22, the container clamp 16 and the fresh culture solution container 22 are both transparent members, the front surface of the fresh culture solution container 22 is also provided with scale marks, the piston 21 is a rubber member, and the upper surface of the piston 21 and the bottom end of the, piston 21 is disc-shaped structure, and piston 21 is the component of rubber material, links to each other through the pipeline between liquid outlet 23 and the ware body 14, and the valve is installed to the inside embedding of liquid outlet 23, can pour into quantitative fresh culture solution into through sending liquid subassembly 17 in to the ware body 14, through constantly instiling fresh culture solution, can carry out periodic replacement with the waste liquid in the ware body 14, provides the guarantee for the embryo development in the ware body 14.
The utility model discloses working process and principle:
the user firstly controls the water pump 10 to start working through the control switch 12, the water pump 10 can pump the waste culture solution in the dish body 14 into the waste liquid collecting bottle 8 after being electrified, then the user holds the handle 18 and rotates clockwise, at the moment, the threaded rod 19 can be driven to rotate positively, the threaded rod 19 is in threaded connection with the fresh culture solution container 22, the piston 21 below the threaded rod can be driven to move upwards at the moment, the piston 21 moves upwards to be higher than the horizontal line of the liquid injection port 20, at the moment, the fresh culture solution is injected into the fresh culture solution container 22 through the liquid injection port 20, the liquid injection port 20 is closed finally, the liquid outlet 23 is opened, the handle 18 is held to rotate anticlockwise, at the moment, the threaded rod 19 can be driven to rotate reversely, the piston 21 is driven to move downwards, the piston 21 moves downwards, so that the fresh culture solution in the fresh culture solution container 22 is, the amount of the injected liquid can be checked by the scale marks on the front surface of the fresh culture liquid container 22, therefore, a fixed amount of fresh culture solution can be injected into the dish body 14 through the solution feeding unit 17, and by continuously dropping the fresh culture solution, the waste liquid in the dish body 14 can be replaced regularly, the development of embryos in the dish body 14 is guaranteed, the user can adjust the first adjusting locking wheel 3, the second adjusting locking wheel 5 and the third adjusting locking wheel 7 to be loose, then the first sleeve 2, the second sleeve 4 and the third sleeve 6 move up and down, then the first sleeve 2, the second sleeve 4 and the third sleeve 6 are fastened by screwing the first adjusting locking wheel 3, the second adjusting locking wheel 5 and the third adjusting locking wheel 7, therefore, the height of the dish body 14 on the support 1 can be adjusted to meet the application requirements of different heights, and the application range is improved.
Finally, it should be noted that: although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications may be made to the embodiments described in the foregoing embodiments, or equivalents may be substituted for elements thereof. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the scope of the protection of the claims of the present invention.

Claims (8)

1. The utility model provides an embryo culture dish with automatic liquid function of trading, includes base (11) and pillar (1) of rigid coupling on base (11), its characterized in that: the outside of base (11) still rigid coupling has controller (12), and the rear surface rigid coupling of base (11) has the battery, the upper surface of base (11) is close to pillar (1) outside and still is provided with waste liquid collecting bottle (8), and the upper surface of base (11) is close to pillar (1) outside still rigid coupling has water pump (10), the outside of pillar (1) from top to bottom slides in proper order and has cup jointed first sleeve (2), second sleeve (4) and third sleeve (6), imbed respectively on the front surface of first sleeve (2), second sleeve (4) and third sleeve (6) and install first regulation locking wheel (3), second regulation locking wheel (5) and third regulation locking wheel (7) through threaded connection rather than self, and the outside of first sleeve (2), second sleeve (4) and third sleeve (6) is rigid coupling respectively has container to press from both sides (16), The culture dish presss from both sides (13) and bottle presss from both sides (9), the inside of container clamp (16) is provided with send liquid subassembly (17), the inside of culture dish clamp (13) is provided with dish body (14), the inside rigid coupling of bottle clamp (9) has waste liquid collecting bottle (8), the upper surface threaded connection of dish body (14) has bottle plug (15).
2. The embryo culture dish with automatic liquid changing function according to claim 1, wherein: the water inlet end of the water pump (10) is connected with the bottom of the dish body (14) through a pipeline, and the water outlet end of the water pump (10) is connected with the upper surface of the waste liquid collecting bottle (8) through a pipeline.
3. The embryo culture dish with automatic liquid changing function according to claim 1, wherein: the sizes of the first sleeve (2), the second sleeve (4) and the third sleeve (6) are equal, and the first sleeve (2), the second sleeve (4) and the third sleeve (6) are all members made of stainless steel.
4. The embryo culture dish with automatic liquid changing function according to claim 1, wherein: send liquid subassembly (17) including handle (18), threaded rod (19), annotate liquid mouth (20), piston (21), fresh culture solution container (22) and liquid outlet (23), the outside rigid coupling of fresh culture solution container (22) has annotates liquid mouth (20), and the upper surface embedding of fresh culture solution container (22) installs threaded rod (19) through threaded connection rather than self, the lower surface center department rigid coupling of fresh culture solution container (22) has liquid outlet (23), and the inner wall laminating of fresh culture solution container (22) has piston (21), the top welding of threaded rod (19) has handle (18).
5. The embryo culture dish with automatic liquid changing function according to claim 4, wherein: the container clamp (16) is fixedly sleeved outside the fresh culture solution container (22), the container clamp (16) and the fresh culture solution container (22) are both transparent members, and the front surface of the fresh culture solution container (22) is also provided with scale marks.
6. The embryo culture dish with automatic liquid changing function according to claim 4, wherein: the piston (21) is a rubber component, the upper surface of the piston (21) and the bottom end of the threaded rod (19) rotate through a bearing, the piston (21) is of a disc-shaped structure, and the piston (21) is a rubber component.
7. The embryo culture dish with automatic liquid changing function according to claim 1, wherein: the bottle clamp (9), the culture dish clamp (13) and the container clamp (16) are all of circular ring structures, and the bottle clamp (9), the culture dish clamp (13) and the container clamp (16) are all components made of alloy steel.
8. The embryo culture dish with automatic liquid changing function according to claim 4, wherein: the liquid outlet (23) is connected with the dish body (14) through a pipeline, and a valve is embedded in the liquid outlet (23).
CN202020139430.2U 2020-01-21 2020-01-21 Embryo culture dish with automatic liquid changing function Active CN211689103U (en)

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Application Number Priority Date Filing Date Title
CN202020139430.2U CN211689103U (en) 2020-01-21 2020-01-21 Embryo culture dish with automatic liquid changing function

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Application Number Priority Date Filing Date Title
CN202020139430.2U CN211689103U (en) 2020-01-21 2020-01-21 Embryo culture dish with automatic liquid changing function

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112522092A (en) * 2020-12-29 2021-03-19 中国科学院苏州生物医学工程技术研究所 Embryo culture and monitoring system
CN112625907A (en) * 2020-12-29 2021-04-09 中国科学院苏州生物医学工程技术研究所 Embryo long-term culture system
CN117343837A (en) * 2023-10-07 2024-01-05 中国人民解放军总医院第六医学中心 Stem cell continuous liquid-changing culture device and application method thereof

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112522092A (en) * 2020-12-29 2021-03-19 中国科学院苏州生物医学工程技术研究所 Embryo culture and monitoring system
CN112625907A (en) * 2020-12-29 2021-04-09 中国科学院苏州生物医学工程技术研究所 Embryo long-term culture system
CN112522092B (en) * 2020-12-29 2024-03-22 中国科学院苏州生物医学工程技术研究所 Embryo culture and monitoring system
CN117343837A (en) * 2023-10-07 2024-01-05 中国人民解放军总医院第六医学中心 Stem cell continuous liquid-changing culture device and application method thereof
CN117343837B (en) * 2023-10-07 2024-04-05 中国人民解放军总医院第六医学中心 Stem cell continuous liquid-changing culture device and application method thereof

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