CN211658503U - Medical oxygen-containing alginate intelligent dressing - Google Patents

Medical oxygen-containing alginate intelligent dressing Download PDF

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Publication number
CN211658503U
CN211658503U CN201922143183.3U CN201922143183U CN211658503U CN 211658503 U CN211658503 U CN 211658503U CN 201922143183 U CN201922143183 U CN 201922143183U CN 211658503 U CN211658503 U CN 211658503U
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oxygen
alginate
rete
film layer
wound
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曹晶晶
周新钦
张明
石锐
杨帅
王川
张建鑫
李果
郑豪
刘剑飞
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Henan Huibo Medical Co ltd
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Henan Huibo Medical Co ltd
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Abstract

The utility model discloses a medical oxygen alginate containing intelligence dressing, including waterproof leak protection gas film layer, waterproof leak protection gas film layer below is equipped with the oxygen suppliment rete, and oxygen suppliment rete below is equipped with the cation exchange rete, and cation exchange rete below is equipped with alginate fibrous layer, is equipped with the wireless sensor of real-time supervision humidity, PH value and oxygen concentration in the alginate fibrous layer, wireless sensor uses with the external controller cooperation of taking timing function, controller and alarm electric connection. The utility model can accelerate wound healing and inhibit anaerobic bacteria growth by the continuous oxygen supply between the oxygen supply film layer and the wound exudate, thereby providing a powerful environment for wound healing; meanwhile, the cation exchange membrane layer is utilized to prevent hydroxide ions from contacting the wound, so that stimulation is generated to the wound, and delayed wound healing is avoided.

Description

Medical oxygen-containing alginate intelligent dressing
Technical Field
The utility model relates to the technical field of functional modification of medical materials, in particular to a medical oxygen-containing alginate intelligent dressing.
Background
The medical gauze is a reticular fabric woven by absorbent cotton yarn or absorbent cotton viscose blended yarn. The medical gauze has stable structure and ventilation function, is mainly used for wrapping wounds in medical treatment, is beneficial to controlling ventilation and discharging seepage, can prevent the wounds from being further infected due to the invasion of external pathogens, and further achieves the purposes of protecting the wounds and promoting the healing of the wounds. The common medical gauze has the advantages of simple structure, low cost, good strength and soft texture, and is widely applied to dressings for skin wound care. However, conventional medical gauze also has a number of significant disadvantages. For example, the moisture absorption performance is poor, and the fabric needs to be replaced frequently when in use, so that the nursing efficiency is reduced, and the nursing cost is increased; the wound surface can not be kept moist, and the healing time is delayed; the gauze has poor barrier effect after permeation, is easy to cause exogenous infection and has poor hemostatic effect; the granulation tissue of the wound surface is easy to grow into meshes of the gauze, so that the gauze fiber is easy to adhere to scabs and is not easy to remove, and pain is caused during replacement.
The calcium alginate fiber has the characteristics of biodegradability, moisture absorption and gel formation, high oxygen permeability, biocompatibility, high ion adsorption and the like, and can be used as medical gauze or dressing. However, when the alginate fiber non-woven fabric is used for wounds with more bleeding, the alginate fiber non-woven fabric is easy to adhere to the wounds, and secondary injury of the wounds is caused frequently.
Oxygen is essential in the wound healing process, and can promote the healing of the wound. Collagen synthesis requires oxygen, growth factors require oxygen, angiogenesis requires oxygen, epidermal cell contraction requires oxygen, and oxygen plays an irreplaceable role in every phase of wound healing. Although alginate dressings or conventional dressings protect wounds and promote wound healing to various degrees, the healing effect is often poor because wounds are in an anoxic state during the healing process. Therefore, at present, a dressing capable of supplying oxygen automatically is urgently needed, an oxygen-rich environment is provided for wounds, the wound healing process is accelerated, the pain of patients is relieved, scars can be repaired, and the wounds are attractive.
The patent application with publication number CN108969197A discloses a dressing for supplying oxygen to wound, which is composed of multiple films based on polymer material as carrier and capable of generating oxygen to supply oxygen to wound, and the dressing is divided into two parts, wherein the first part mainly comprises an anti-air leakage protective film, a polymer gel containing hydrogen peroxide, an air-permeable and water-impermeable film (with micropores on the film), and a protective layer from top to bottom. The second part is composed of a protective layer, a manganese dioxide film, a breathable impermeable film and a water absorption pad (or other sheets made of sodium alginate), wherein the hydrogen peroxide in the polymer gel containing the hydrogen peroxide can be replaced by other eutrophic compounds, and the manganese dioxide film as a catalyst can be replaced by other catalysts. Although the oxygen supply dressing for the wound can provide an oxygen-rich environment for the wound, accelerate the wound healing and kill anaerobic bacteria, the oxygen supply dressing has a complex composition, the reaction liquid of oxygen is supplied by water in hydrogel, and the oxygen production amount of the oxygen supply dressing depends on the water content in the hydrogel. Can not be according to the wound size and how much intelligent control oxygen demand of wound exudate, hydrogen peroxide solution itself is as a disinfectant, has extremely strong irritability, is used for disinfecting for the object surface for the wound easily causes the stimulation to the wound, is unfavorable for the recovery of wound, and this preparation mode needs the cooperation of two parts to use, and troublesome poeration is unfavorable for alleviateing medical staff operation burden, and two parts structure, has increased the raw materials and has stored the requirement, cost increase.
The patent application with publication number CN108836633A discloses a dressing for supplying oxygen to wound based on oxygen generated by multiple polymer materials or composite membrane structure (sheet) composed of the polymer materials as carriers, and its production process, wherein the dressing mainly comprises an air leakage-proof protective film, a water absorption and storage pad, an oxygen supply film (sheet) and a water permeable and water absorbent material; the oxygen supply membrane (sheet) (3) is in a structure of a permeable and air-permeable composite membrane (sheet), and the oxygen supply membrane (sheet) (3) is a porous membrane which contains an oxidant (such as sodium percarbonate) and a catalyst (such as manganese dioxide) and is wrapped outside. Although the structure of the patent can generate oxygen and can directly participate in reaction according to the utilization of exudate, sodium percarbonate and a catalyst in the dressing are combined with wound exudate to form sodium carbonate and oxygen, the sodium carbonate is weak base, and sodium carbonate solution formed by the sodium percarbonate is irritant to the wound after flowing back or being absorbed by an absorption pad and contacting the wound, and the formed weak alkaline environment is not beneficial to the healing of the wound because the wound is more beneficial to the healing in the weak acidic environment. And the dressing needs to be replaced in time according to the state of the exudate and the dressing due to high exudation so as to ensure that the wound is not soaked and the oxygen supply amount of the wound meets the requirement. The surface of the water permeable and water absorbing material is coated with soft silicone or covered with sodium alginate, and if the water permeable and water absorbing material is coated with soft silicone, the generated oxygen is limited from reaching the wound surface because the soft silicone is not permeable; in the case of sodium alginate coating, sodium alginate can absorb the exudate and form a gel, but it does not have the hemostatic and blood coagulation effects of calcium alginate.
SUMMERY OF THE UTILITY MODEL
The invention aims to provide a medical oxygen-containing alginate intelligent dressing to solve the problems in the prior art. The utility model adopts the following technical scheme:
the utility model provides a medical oxygen alginate containing intelligence dressing, includes waterproof leak protection rete, waterproof leak protection rete below is equipped with the oxygen suppliment rete, and oxygen suppliment rete below is equipped with the cation exchange rete, and cation exchange rete below is equipped with alginate fibrous layer, is equipped with the wireless sensor of real-time supervision humidity, PH value and oxygen concentration in the alginate fibrous layer, wireless sensor uses with the external controller cooperation of taking the timer, controller and alarm electric connection.
Furthermore, the waterproof and air-leakage-proof film layer is a one-way breathable water-blocking and bacterium-blocking film layer.
Further, the oxygen supply film layer is a calcium peroxide film layer.
Further, sodium oxide particles are dispersed on the calcium peroxide film layer.
Further, the alginate fiber layer is a calcium alginate fiber layer or a calcium alginate and sodium alginate blended fiber layer.
Furthermore, a protective layer is arranged below the alginate fiber layer
The utility model has the advantages as follows:
1. the utility model can accelerate wound healing and inhibit anaerobic bacteria growth by the continuous oxygen supply between the oxygen supply film layer and the wound exudate, thereby providing a powerful environment for wound healing; meanwhile, the cation exchange membrane layer is utilized to prevent hydroxide ions from contacting the wound, so that stimulation is generated to the wound, and delayed wound healing is avoided.
2. Calcium ions released by the calcium peroxide film layer and sodium ions released by the sodium oxide particles are conducted to alginate fibers and are subjected to calcium ion exchange with calcium alginate fibers in the alginate fibers, so that calcium ions are promoted to be dissociated to wounds, the coagulation of the wounds is promoted, the healing of the wounds is accelerated, on the other hand, sodium ions are combined with the alginate to form sodium alginate gel, the formed dressing is excellent in gelation effect due to a large amount of supplied sodium ions, the dressing is prevented from being adhered to the wounds, and the calcium ions conducted from the calcium peroxide film layer supplement the calcium ions released by the alginate, so that the coagulation effect is enhanced, and the coagulation occurrence time is shortened.
3. The utility model discloses a humidity, pH value and the oxygen concentration of wireless sensor real-time supervision wound in the alginate fibrous layer, dressing are changed in the intelligence suggestion to avoid changing the flooding that untimely caused or change the dressing in advance and cause the waste of dressing and increase medical personnel's burden etc..
Drawings
Fig. 1 is a schematic structural diagram of the present invention.
Shown in the figure: the device comprises a waterproof and anti-leakage air film layer 1, a calcium peroxide film layer 2, a cation exchange film layer 3, an alginate fiber layer 4, a protective layer 5, sodium oxide particles 6, a controller 7, an alarm 8 and a wireless sensor 9.
Detailed Description
As shown in fig. 1, the medical oxygen-containing alginate intelligent dressing comprises a waterproof air-leakage-proof film layer 1, wherein the waterproof air-leakage-proof film layer 1 is a one-way breathable water-blocking bacteria-blocking film layer. The waterproof and air-leakage-proof film layer 1 is a one-way air-permeable and water-blocking bacteria-blocking film, only allows oxygen in the air to enter a wound through the waterproof and air-leakage-proof film layer, prevents generated oxygen from overflowing through the waterproof and air-leakage-proof film layer, and can also prevent external moisture, bacteria and the like from entering the dressing, thereby preventing the wound from being infected.
An oxygen supply film layer is arranged below the waterproof and air leakage-proof film layer 1, the oxygen supply film layer is a calcium peroxide film layer 2, and sodium oxide particles 6 are dispersedly arranged on the calcium peroxide film layer 2.
The oxygen suppliment rete below is equipped with cation exchange rete 3, and cation exchange rete 3 is the rete that only allows cation to permeate through, does not allow anion to permeate through, and 3 below on the cation exchange rete are equipped with alginate fibrous layer 4, and alginate fibrous layer 4 is calcium alginate fibrous layer or calcium alginate and sodium alginate blend fiber layer, and it is the wound contact layer. The size of the waterproof and air leakage-proof film layer 1 is larger than or equal to that of the alginate fiber layer 4, and the size of the alginate fiber layer 4 is as large as that of the calcium peroxide film layer 2 and the cation exchange film layer 3 or slightly larger than that of the calcium peroxide film layer 2 and the cation exchange film layer 3, so that the generated oxygen can be completely absorbed by the alginate fiber layer 4.
Be equipped with the wireless sensor 9 of real-time supervision humidity, pH value and oxygen concentration in alginate fibrous layer 4, wireless sensor 9 uses with the external controller 7 cooperation of taking the timer, controller 7 and alarm 8 electric connection. A protective layer 5 is arranged below the alginate fiber layer 4, and the protective layer 5 is release paper or a release film which is removed when in use.
The utility model discloses an action principle as follows:
and (3) removing the protective layer 5, covering the wound part with the alginate fiber layer 4, wherein when exudate contacts the alginate fiber layer 4, the exudate can be absorbed by the calcium alginate fiber layer 4 and is conducted to the calcium peroxide film layer 2 through the cation exchange film layer 3, when water in the exudate contacts the calcium peroxide, oxygen and calcium ions are generated, and meanwhile, sodium ions in the sodium oxide particles 6 are released, and at the moment, the oxygen, the calcium ions and the sodium ions are conducted to the alginate fiber layer 4 through the cation exchange film layer 3 and are transmitted to the wound.
Oxygen is supplied to the wound, on one hand, the wound healing is accelerated, on the other hand, the growth of anaerobic bacteria is inhibited, and a powerful environment is provided for the wound healing. The sodium ions conducted to the calcium alginate salt fiber layer or the calcium alginate/sodium alginate blended fiber layer are subjected to ion exchange with the calcium ions in the calcium alginate fiber layer 4, so that on one hand, the calcium ions are promoted to be dissociated to the wound to promote the blood coagulation of the wound and accelerate the healing of the wound, on the other hand, the sodium ions are combined with the alginate to form sodium alginate gel, and a large amount of supplied sodium ions enable the formed dressing to have excellent gelation effect, and the dressing is prevented from being adhered to the wound.
Calcium ions conducted from the cation exchange membrane layer 3 to the alginate fiber layer 4 and free calcium ions in the alginate fiber layer 4 play a role in hemostasis together, so that the hemostasis effect of the dressing is enhanced, and the calcium ions at the wound are continuously supplemented due to continuous release of the calcium ions of the calcium peroxide membrane layer 2, so that the long-term hemostasis effect of the dressing is enhanced, and the hemostasis problem of a wound with severe bleeding is also solved.
The wireless sensor 9 in the alginate fiber layer 4 monitors the humidity, the PH value and the oxygen concentration of the wound in real time, the wireless sensor 9 is matched with an external controller for use, and the controller 7 is electrically connected with the alarm 8. The controller 8 is preset with application time, a maximum humidity critical value, a PH critical value and a minimum oxygen concentration critical value, and when the application time exceeds the preset time, the humidity, the PH value and the oxygen concentration reach the critical values, the controller 7 starts the alarm 8 to give an alarm to prompt the dressing change.
The above embodiments are only used for illustrating but not limiting the technical solutions of the present invention, and although the present invention is described in detail with reference to the above embodiments, those of ordinary skill in the art should understand that: the present invention may be modified or substituted with equivalents without departing from the spirit and scope of the invention, which should be construed as being limited only by the claims.

Claims (6)

1. The utility model provides a medical oxygen alginate intelligence dressing that contains, its characterized in that, including waterproof leak protection gas rete, waterproof leak protection gas rete below is equipped with the oxygen suppliment rete, and oxygen suppliment rete below is equipped with the cation exchange rete, and cation exchange rete below is equipped with alginate fiber layer, is equipped with the wireless sensor of real-time supervision humidity, PH value and oxygen concentration in the alginate fiber layer, wireless sensor uses with the external controller cooperation of taking the timer, controller and alarm electric connection.
2. The medical oxygen-containing alginate smart dressing according to claim 1, wherein the waterproof and air-leakage-proof film layer is a one-way air-permeable water-blocking and bacteria-blocking film layer.
3. The medical oxygen-containing alginate intelligent dressing according to claim 1, wherein the oxygen supply film layer is a calcium peroxide film layer.
4. The medical oxygen-containing alginate smart dressing according to claim 3, wherein sodium oxide particles are dispersed on the calcium peroxide film layer.
5. The medical oxygen-containing alginate smart dressing according to claim 1, wherein the alginate fiber layer is a calcium alginate fiber layer.
6. The medical oxygen-containing alginate smart dressing according to claim 1, wherein a protective layer is arranged below the alginate fiber layer.
CN201922143183.3U 2019-12-04 2019-12-04 Medical oxygen-containing alginate intelligent dressing Active CN211658503U (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113248736A (en) * 2021-05-31 2021-08-13 华中科技大学 Anti-adhesion hydrogel, preparation method and application of anti-adhesion hydrogel in preparation of epidermal wound dressing
CN114099141A (en) * 2020-12-14 2022-03-01 河南驼人医疗器械研究院有限公司 Microfluid self-conduction wound monitoring type intelligent dressing and preparation method thereof
US20220326205A1 (en) * 2021-04-08 2022-10-13 Qingdao University, China Bismuth oxide based ammonia sensor

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114099141A (en) * 2020-12-14 2022-03-01 河南驼人医疗器械研究院有限公司 Microfluid self-conduction wound monitoring type intelligent dressing and preparation method thereof
US20220326205A1 (en) * 2021-04-08 2022-10-13 Qingdao University, China Bismuth oxide based ammonia sensor
US11913930B2 (en) * 2021-04-08 2024-02-27 Qingdao University, China Bismuth oxide based ammonia sensor
CN113248736A (en) * 2021-05-31 2021-08-13 华中科技大学 Anti-adhesion hydrogel, preparation method and application of anti-adhesion hydrogel in preparation of epidermal wound dressing
CN113248736B (en) * 2021-05-31 2022-01-07 华中科技大学 Anti-adhesion hydrogel, preparation method and application of anti-adhesion hydrogel in preparation of epidermal wound dressing

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