CN211553888U

CN211553888U - Glass chromatographic column

Info

Publication number: CN211553888U
Application number: CN201921837058.6U
Authority: CN
Inventors: 周晓渭; 彭功名
Original assignee: Shanghai Zhourui Biotechnology Co ltd
Current assignee: Shanghai Zhourui Biotechnology Co ltd
Priority date: 2019-10-29
Filing date: 2019-10-29
Publication date: 2020-09-22
Anticipated expiration: 2029-10-29

Abstract

The utility model relates to the technical field of chromatographic columns, and discloses a glass chromatographic column, which solves the problems that in the using process of a common chromatographic column, liquid can impact the filler in the chromatographic column when flowing in, can have adverse effect on the separation process, and the common chromatographic column has poor sealing performance after being used for a long time; the utility model discloses, through the cooperation use of the cassette that sets up, cotton layer, otter board and pressure spring etc. can use the otter board to fix the cotton layer under pressure spring's effect, avoid liquid when flowing in, the ion exchange resin inside the column casing fluctuates, avoids taking place harmful effects to the separation process; the sealing performance of the chromatographic column joint can be further improved by matching the arranged first gasket, the sealing filler, the second gasket, the sealing gasket and the like, so that the sealing performance of the chromatographic column is improved.

Description

Glass chromatographic column

Technical Field

The utility model belongs to the technical field of the chromatographic column, specifically be a glass chromatographic column.

Background

Chromatographic columns can be divided into two categories, packed columns and open tubular columns; most of the materials are made of metal or glass; the tube has a shape of a straight tube, a coil, a U-shaped tube, etc. Liquid chromatography generally adopts a packed column; the separation performance of a chromatography column depends on the stationary phase chosen, as well as the preparation and operating conditions of the column; chromatography is a separation and analysis means, and separation is the core, so the chromatographic column which plays a role in separation is the heart of a chromatographic system.

In the process of using a general chromatographic column, when liquid flows in, the liquid can impact a packing in the chromatographic column, the separation process can be adversely affected, and the general chromatographic column is poor in sealing performance after being used for a long time and is easy to leak.

Disclosure of Invention

To the situation, for overcoming prior art's defect, the utility model provides a glass chromatographic column, the effectual in-process of having solved general chromatographic column and using, liquid can produce the impact to the inside packing of chromatographic column when flowing in, can produce harmful effects to the separation process, and the relatively poor problem of sealing performance after general chromatographic column uses for a long time.

In order to achieve the above object, the utility model provides a following technical scheme: the utility model provides a glass chromatographic column, includes the column casing, the column head is installed on the top of column casing, and the mid-mounting that goes up the column head has even pipe as an organic whole, and the cassette is installed at the top of column casing, and the top packing of cassette has the cotton layer, and the otter board is installed on the top on cotton layer, and compression spring is installed on the top of otter board, and the sleeve is installed to the bottom of column casing, and the column head is installed down to the bottom of column casing.

Preferably, a first gasket is installed at the top of the sleeve, the bottom end of the first gasket is filled with sealing filler, and a second gasket is installed at the bottom end of the sealing filler.

Preferably, a sealing gasket is arranged inside the top end of the lower column joint and is positioned between the column tube and the lower column joint.

Preferably, the middle part of the column tube is filled with ion exchange resin.

Preferably, the column tube is made of a glass material, and the inner wall of the column tube is polished.

Preferably, the outer wall of the column tube is processed by a frosted process.

Compared with the prior art, the beneficial effects of the utility model are that:

1) in the work, the cotton layer can be fixed by the screen plate under the action of the compression spring through the matching use of the filter disc, the cotton layer, the screen plate, the compression spring and the like, so that the phenomenon that the ion exchange resin in the column tube fluctuates when liquid flows in is avoided, and the adverse effect on the separation process is avoided;

2) the utility model discloses a chromatographic column, including the chromatographic column, the first gasket that sets up, the second gasket that sets up, the first gasket that sets up.

Drawings

The accompanying drawings are included to provide a further understanding of the invention, and are incorporated in and constitute a part of this specification, illustrate embodiments of the invention, and together with the description serve to explain the invention and not to limit the invention. In the drawings:

fig. 1 is a schematic structural view of the present invention;

FIG. 2 is a schematic view of the internal structure of the present invention;

fig. 3 is an enlarged schematic structural view of a point a in fig. 2 according to the present invention;

fig. 4 is an enlarged schematic structural view of the utility model at the position B in fig. 2;

in the figure: 1. a column tube; 2. an upper column joint; 3. a conduit; 4. a filter disc; 5. a cotton layer; 6. a screen plate; 7. a compression spring; 8. a sleeve; 9. a lower column joint; 10. a first gasket; 11. sealing and filling; 12. a second gasket; 13. a gasket; 14. ion exchange resins.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments; based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.

Embodiment one, given by fig. 1-4, the utility model discloses a column casing 1, column joint 2 is installed on the top of column casing 1, the mid-mounting of going up column joint 2 has even pipe 3 as an organic whole, be convenient for with liquid input, cassette 4 is installed at the top of column casing 1, can filter liquid, the top packing of cassette 4 has cotton layer 5, otter board 6 is installed on cotton layer 5's top, compression spring 7 is installed on otter board 6's top, sleeve 8 is installed to the bottom of column casing 1, lower column joint 9 is installed to the bottom of column casing 1, can avoid ion exchange resin 14 to take place undulantly.

In the second embodiment, the first gasket 10 is attached to the top of the sleeve 8, the packing 11 is filled in the bottom end of the first gasket 10, and the second gasket 12 is attached to the bottom end of the packing 11, so that the sealing property at the bottom end of the column can be increased.

In the third embodiment, on the basis of the first embodiment, the gasket 13 is installed inside the top end of the lower column joint 9, and the gasket 13 is located between the column tube 1 and the lower column joint 9, so that the sealing performance of the chromatographic column can be further improved.

Fourth embodiment, on the basis of the first embodiment, the middle part of the column tube 1 is filled with the ion exchange resin 14, so that the liquid can be conveniently separated.

In the fifth embodiment, on the basis of the first embodiment, the column tube 1 is made of a glass material, and the inner wall of the column tube is polished, so that friction force can be reduced, and the flowing performance of liquid can be improved.

Sixth, on the basis of the first embodiment, the outer wall of the column tube 1 is processed by a frosting process, so that a user can conveniently take the chromatographic column.

The working principle is as follows: during operation, at first through the filter 4 that sets up, cotton layer 5, the cooperation of otter board 6 and pressure spring 7 etc. is used, can be under pressure spring 7's effect, use otter board 6 to fix cotton layer 5, when avoiding liquid to flow in, the inside ion exchange resin 14 of column pipe 1 takes place undulantly, avoid taking place harmful effects to the separation process, through the first gasket 10 that sets up, gland packing 11, the cooperation of second gasket 12 and sealed pad 13 etc. is used, can play primary seal through sealed pad 13, then through first gasket 10, the effect of secondary seal is played to second gasket 12, gland packing 11 of packing between the two can further improve the sealing performance of its junction simultaneously, thereby improve the sealing performance of chromatographic column.

It is noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus.

Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims

1. A glass chromatographic column comprising a column tube (1), characterized in that: the utility model discloses a novel column pipe, including pillar tube (1), pillar joint (2) are installed on the top of pillar tube (1), the mid-mounting of going up pillar joint (2) has pipe (3) even as an organic whole, cassette (4) are installed at the top of pillar tube (1), the top packing of cassette (4) has cotton layer (5), otter board (6) are installed on the top of cotton layer (5), hold-down spring (7) are installed on the top of otter board (6), sleeve (8) are installed to the bottom of pillar tube (1), pillar joint (9) are installed down to the bottom of pillar tube (1).

2. A glass chromatography column as claimed in claim 1, wherein: a first gasket (10) is installed at the top of the sleeve (8), a sealing filler (11) is filled at the bottom end of the first gasket (10), and a second gasket (12) is installed at the bottom end of the sealing filler (11).

3. A glass chromatography column as claimed in claim 1, wherein: the inside mounting on lower post joint (9) top has sealed pad (13), and sealed pad (13) are located between column pipe (1) and lower post joint (9).

4. A glass chromatography column as claimed in claim 1, wherein: the middle part of the column tube (1) is filled with ion exchange resin (14).

5. A glass chromatography column as claimed in claim 1, wherein: the column tube (1) is made of glass materials, and the inner wall of the column tube is polished.

6. A glass chromatography column as claimed in claim 1, wherein: the outer wall of the column tube (1) is processed by adopting a frosted process.