CN211513632U - A filter equipment for valaciclovir hydrochloride production - Google Patents
A filter equipment for valaciclovir hydrochloride production Download PDFInfo
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- CN211513632U CN211513632U CN201922383167.1U CN201922383167U CN211513632U CN 211513632 U CN211513632 U CN 211513632U CN 201922383167 U CN201922383167 U CN 201922383167U CN 211513632 U CN211513632 U CN 211513632U
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- Prior art keywords
- filter element
- rotating rod
- tank body
- filter
- brush
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- ZCDDBUOENGJMLV-QRPNPIFTSA-N Valacyclovir hydrochloride Chemical compound Cl.N1C(N)=NC(=O)C2=C1N(COCCOC(=O)[C@@H](N)C(C)C)C=N2 ZCDDBUOENGJMLV-QRPNPIFTSA-N 0.000 title claims abstract description 17
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 14
- 239000007788 liquid Substances 0.000 claims abstract description 35
- 238000001914 filtration Methods 0.000 claims abstract description 14
- 235000017166 Bambusa arundinacea Nutrition 0.000 claims description 8
- 235000017491 Bambusa tulda Nutrition 0.000 claims description 8
- 241001330002 Bambuseae Species 0.000 claims description 8
- 235000015334 Phyllostachys viridis Nutrition 0.000 claims description 8
- 239000011425 bamboo Substances 0.000 claims description 8
- 229940064636 valacyclovir hydrochloride Drugs 0.000 claims description 8
- 239000010865 sewage Substances 0.000 claims description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 6
- 238000011001 backwashing Methods 0.000 claims description 5
- 239000012530 fluid Substances 0.000 claims description 3
- 239000002699 waste material Substances 0.000 description 7
- 238000006243 chemical reaction Methods 0.000 description 3
- 238000011010 flushing procedure Methods 0.000 description 3
- 238000007664 blowing Methods 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 2
- 230000008878 coupling Effects 0.000 description 2
- 238000010168 coupling process Methods 0.000 description 2
- 238000005859 coupling reaction Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 208000007514 Herpes zoster Diseases 0.000 description 1
- 208000029433 Herpesviridae infectious disease Diseases 0.000 description 1
- 229960004150 aciclovir Drugs 0.000 description 1
- MKUXAQIIEYXACX-UHFFFAOYSA-N aciclovir Chemical compound N1C(N)=NC(=O)C2=C1N(COCCO)C=N2 MKUXAQIIEYXACX-UHFFFAOYSA-N 0.000 description 1
- 239000002156 adsorbate Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 210000004877 mucosa Anatomy 0.000 description 1
- 238000003541 multi-stage reaction Methods 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 229940002612 prodrug Drugs 0.000 description 1
- 239000000651 prodrug Substances 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 238000003466 welding Methods 0.000 description 1
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- Filtration Of Liquid (AREA)
Abstract
A filtering device for valaciclovir hydrochloride production comprises a tank body, wherein the tank body is provided with a liquid inlet and a liquid outlet, a filter element is arranged in the tank body, the outer surface of the filter element is provided with a brush body, the brush body is connected with a rotating rod, and the rotating rod is driven to rotate by a driving device; the driving device is arranged outside the tank body, and the rotating rod is connected with the tank body through a bearing. The utility model discloses compare traditional filter equipment and compare, can avoid the filter screen to adhere to dirty, and influence the trafficability characteristic of filter screen, can improve filtration efficiency.
Description
Technical Field
The utility model belongs to valaciclovir hydrochloride production facility field, in particular to a filter equipment for valaciclovir hydrochloride production.
Background
Valacyclovir hydrochloride is a prodrug of acyclovir, and is mainly used for treating herpes zoster and simple herpes virus infection of skin mucosa. In the preparation of valacyclovir hydrochloride, a multistage reaction kettle and a filtering device are needed, for example, a 'valacyclovir hydrochloride reaction device' disclosed in chinese patent document CN 208700931U, the filtering device filters off waste residues in the reaction kettle, and thus clear liquid is conveyed to the next reaction kettle. The filter element of the existing filter device is easy to block, so that the liquid passing performance is influenced, the existing technical means for cleaning the adsorbate on the filter element is a method of back blowing, but the blowing effect of gas in liquid is limited, the air pressure in the device is easy to increase, and the device is very unsafe.
Disclosure of Invention
In view of the technical problem that the background art exists, the utility model provides a filter equipment for production of valaciclovir hydrochloride, the utility model discloses compare traditional filter equipment and compare, can avoid the filter screen to adhere to dirty, and influence the trafficability characteristic of filter screen, can improve filtration efficiency.
In order to solve the technical problem, the utility model discloses following technical scheme has been taken and has been realized:
a filtering device for valaciclovir hydrochloride production comprises a tank body, wherein the tank body is provided with a liquid inlet and a liquid outlet, a filter element is arranged in the tank body, the outer surface of the filter element is provided with a brush body, the brush body is connected with a rotating rod, and the rotating rod is driven to rotate by a driving device; the driving device is arranged outside the tank body, and the rotating rod is connected with the tank body through a bearing.
In the preferred scheme, the filter element is in a conical cylinder structure, the tip end of the filter element is positioned on one side of the liquid inlet, and the other end of the filter element is positioned on one side of the liquid outlet; the most advanced of filter core is equipped with protects a section of thick bamboo, protects a section of thick bamboo and is connected with dwang one end through the bearing, and the dwang other end runs through a jar external wall setting, and is connected through the bearing between dwang and the jar external wall.
In the preferred scheme, the number of the brush body be a plurality of, a plurality of brush bodies set up around the filter core axis ring-type, the one end of the brush body all is connected on the dwang.
In the preferred scheme, the middle section of the tank body is of a straight cylinder structure, and two ends of the straight cylinder are of cone structures; the axes of the liquid outlet, the rotating rod and the filter element are all arranged in a superposition way; a back washing water inlet is arranged on the tank body positioned on the same side of the liquid outlet, and a sewage outlet is arranged on the straight cylinder; the liquid inlet is positioned on the inclined wall of the vertebral body at one side of the rotating rod.
In the preferred scheme, drive arrangement include the motor, motor axis of rotation and drive wheel coaxial coupling, the drive wheel passes through the belt with follow the driving wheel and is connected, follow driving wheel and dwang coaxial coupling.
In the preferred scheme, pressure points are respectively arranged on two sides of the fluid passing through the filter element, the pressure points are connected with a differential pressure gauge through a pressure pipeline, and the differential pressure gauge is positioned on the lower part of the tank body.
This patent can reach following beneficial effect:
the mixed liquid that lets in from reation kettle gets into by the inlet, and the filter core filters the waste residue, and there is some waste residues can the adhesion on the filter core surface, and drive arrangement drives the brush body and rotates, and the brush body is cleared up the plug on filter core surface, has improved the trafficability characteristic of liquid. The differential pressure gauge is used for detecting the trafficability of two sides of the filter element, and when the differential pressure value of the differential pressure gauge rises to a certain limit value, the filter element is proved to be seriously blocked and needs to be backwashed. The utility model discloses compare traditional filter equipment and compare, can avoid the filter screen to adhere to dirty, and influence the trafficability characteristic of filter screen, can improve filtration efficiency.
Drawings
The invention will be further explained with reference to the following figures and examples:
FIG. 1 is a cross-sectional view of the present invention;
FIG. 2 is a view of the appearance structure of the present invention;
FIG. 3 is an internal structure view of the present invention;
FIG. 4 is a diagram of the structure of the filter element of the present invention;
FIG. 5 is a structural view of the brush body of the present invention;
fig. 6 is a schematic view of the installation differential pressure gauge of the present invention.
In the figure: the device comprises a tank body 1, a liquid inlet 101, a liquid outlet 102, a filter element 2, a brush body 3, a rotating rod 4, a protective cylinder 5, a backwashing water inlet 6, a sewage outlet 7, a motor 81, a driving wheel 82, a driven wheel 83 and a pressure difference meter 9.
Detailed Description
The preferable scheme is as shown in fig. 1 to 5, the filtering device for valaciclovir hydrochloride production comprises a tank body 1, wherein the tank body 1 is provided with a liquid inlet 101 and a liquid outlet 102, a filter element 2 is arranged in the tank body 1, a brush body 3 is arranged on the outer surface of the filter element 2, the brush body 3 is connected with a rotating rod 4, and the rotating rod 4 is driven by a driving device to rotate; the driving device is arranged outside the tank body 1, and the rotating rod 4 is connected with the tank body 1 through a bearing. The mixed liquid that lets in from reation kettle gets into by inlet 101, and filter core 2 filters the waste residue, and there is some waste residues can the adhesion on 2 surfaces of filter core, and this technical scheme adopts rotatory brush body 3 to clear up the plug on 2 surfaces of filter core, has improved the trafficability characteristic of liquid. Compared with the prior art, the technical scheme has better cleaning effect on the filter element 2 and higher efficiency.
Further, as shown in fig. 3 and 4, the filter element 2 is a conical cylinder structure, the tip of the filter element 2 is located at the liquid inlet 101 side, and the other end of the filter element 2 is located at the liquid outlet 102 side; the most advanced of filter core 2 is equipped with protects a section of thick bamboo 5, protects a section of thick bamboo 5 and is connected with 4 one ends of dwang through the bearing, and the dwang 4 other end runs through the setting of 1 outer wall of the jar body, and is connected through the bearing between the dwang 4 and the 1 outer wall of the jar body. The main support of dwang 4 is the junction of dwang 4 and jar body 1 outer wall, and for further improving the rotatory stability of dwang 4, has increased and has protected a 5 structures, protects 5 one end of a section of thick bamboo and be tubaeform opening, and tubaeform opening is used for cup jointing 2 most advanced positions at the filter core, filter core 2 and protect between the section of thick bamboo 5 welded fastening, and the other end that protects a 5 is equipped with the circular recess, and the circular recess passes through the bearing and is connected with dwang 4.
Further, the quantity of the brush bodies 3 is a plurality of, the brush bodies 3 are annularly arranged around the axis of the filter element 2, and one ends of the brush bodies 3 are connected to the rotating rod 4. The preferred 2-3 brush bodies 3, the brush body 3 includes stress pole and brush hair two parts, and the stress pole adopts the metal pole, and stress pole one end welding is on dwang 4.
Further, the middle section of the tank body 1 is of a straight cylinder structure, and two ends of the straight cylinder are of cone structures; the liquid outlet 102, the rotating rod 4 and the axis of the filter element 2 are all arranged in a superposition way; a backwashing water inlet 6 is arranged on the tank body 1 positioned at the same side of the liquid outlet 102, and a sewage outlet 7 is arranged on the straight cylinder; the liquid inlet 101 is positioned on the inclined wall of the vertebral body at one side of the rotating rod 4. As shown in fig. 2, the cone structure on the left side of the tank body 1 is a cover body, the cone structure on the right side of the tank body 1 and the straight cylinder structure are integrally formed to form a tank body, and the cover body and the tank body are connected by flanges. As shown in fig. 3 and 4, the edge of the filter element 2 is connected with the cover body through a flange.
When the device is used for a period of time, the clearance of equipment outage is utilized, when the filter element 2 is backwashed, the liquid inlet 101 and the liquid outlet 102 are cut off, clear water is introduced from the backwashing water inlet 6, the driving device is started, the blockage on the filter element 2 is backflushed and cleaned, and sewage is discharged through the sewage outlet 7.
Further, the driving device comprises a motor 81, the rotating shaft of the motor 81 is coaxially connected with a driving wheel 82, the driving wheel 82 is connected with a driven wheel 83 through a belt, and the driven wheel 83 is coaxially connected with the rotating rod 4. The motor 81 can be a speed reducing motor, and the rotating speed of the rotating rod 4 is kept at 15-30 revolutions per minute.
Further, as shown in fig. 6, pressure taking points are respectively arranged on two sides of the fluid passing through the filter element 2, the pressure taking points are connected with a differential pressure gauge 9 through pressure taking pipelines, and the differential pressure gauge 9 is positioned at the lower part of the tank body 1. The differential pressure gauge 9 is used for detecting the trafficability of the two sides of the filter element 2, and when the differential pressure value of the differential pressure gauge 9 rises to a certain limit value, the filter element 2 is proved to be seriously blocked and needs to be backwashed.
The working principle of the whole device is as follows:
the mixed liquid that lets in from reation kettle gets into by inlet 101, and filter core 2 filters the waste residue, has partial waste residue can the adhesion on 2 surfaces of filter core, and drive arrangement drives dwang 4 and rotates, and the rotatory brush body 3 that drives of dwang 4 rotates, and the brush body 3 clears up the plug on 2 surfaces of filter core, has improved the trafficability characteristic of liquid. The differential pressure gauge 9 is used for detecting the trafficability of the two sides of the filter element 2, and when the differential pressure value of the differential pressure gauge 9 rises to a certain limit value, the filter element 2 is proved to be seriously blocked and needs to be backwashed. The back-flushing operation of the device is preferably set at the equipment shut-down interval to perform the flushing operation of the filter element 2. If the differential pressure gauge 9 detects that the filter element is seriously blocked, the filtering operation needs to be stopped and the back flushing operation needs to be carried out.
Claims (6)
1. The utility model provides a filter equipment for production of valaciclovir hydrochloride, includes a jar body (1), and a jar body (1) is equipped with inlet (101) and liquid outlet (102), is equipped with filter core (2), its characterized in that in jar body (1): the outer surface of the filter element (2) is provided with a brush body (3), the brush body (3) is connected with a rotating rod (4), and the rotating rod (4) is driven by a driving device to rotate; the driving device is arranged outside the tank body (1), and the rotating rod (4) is connected with the tank body (1) through a bearing.
2. The filtration device of claim 1 for use in valacyclovir hydrochloride production wherein: the filter element (2) is in a conical cylinder structure, the tip end of the filter element (2) is positioned on one side of the liquid inlet (101), and the other end of the filter element (2) is positioned on one side of the liquid outlet (102); the most advanced of filter core (2) is equipped with protects a section of thick bamboo (5), protects a section of thick bamboo (5) and is connected with dwang (4) one end through the bearing, and dwang (4) other end runs through jar body (1) outer wall setting, and is connected through the bearing between dwang (4) and the jar body (1) outer wall.
3. The filtration device of claim 2 for use in valacyclovir hydrochloride production wherein: the quantity of the brush bodies (3) is a plurality of, the brush bodies (3) are annularly arranged around the axis of the filter element (2), and one end of each brush body (3) is connected to the rotating rod (4).
4. The filtration device of claim 3 for use in valacyclovir hydrochloride production wherein: the middle section of the tank body (1) is of a straight cylinder structure, and two ends of the straight cylinder are of cone structures; the axes of the liquid outlet (102), the rotating rod (4) and the filter element (2) are all superposed; a backwashing water inlet (6) is arranged on the tank body (1) positioned at the same side of the liquid outlet (102), and a sewage outlet (7) is arranged on the straight cylinder; the liquid inlet (101) is positioned on the inclined wall of the vertebral body at one side of the rotating rod (4).
5. The filtration device of claim 1 for use in valacyclovir hydrochloride production wherein: the driving device comprises a motor (81), a rotating shaft of the motor (81) is coaxially connected with a driving wheel (82), the driving wheel (82) is connected with a driven wheel (83) through a belt, and the driven wheel (83) is coaxially connected with a rotating rod (4).
6. The filtration device of claim 1 for use in valacyclovir hydrochloride production wherein: the two sides of the fluid passing through the filter element (2) are respectively provided with a pressure taking point, the pressure taking points are connected with a differential pressure gauge (9) through a pressure taking pipeline, and the differential pressure gauge (9) is positioned at the lower part of the tank body (1).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201922383167.1U CN211513632U (en) | 2019-12-26 | 2019-12-26 | A filter equipment for valaciclovir hydrochloride production |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201922383167.1U CN211513632U (en) | 2019-12-26 | 2019-12-26 | A filter equipment for valaciclovir hydrochloride production |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN211513632U true CN211513632U (en) | 2020-09-18 |
Family
ID=72447314
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201922383167.1U Active CN211513632U (en) | 2019-12-26 | 2019-12-26 | A filter equipment for valaciclovir hydrochloride production |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN211513632U (en) |
-
2019
- 2019-12-26 CN CN201922383167.1U patent/CN211513632U/en active Active
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| GR01 | Patent grant | ||
| GR01 | Patent grant |