CN211433262U - Freezing balloon catheter for treating clinical pulmonary arterial hypertension - Google Patents

Freezing balloon catheter for treating clinical pulmonary arterial hypertension Download PDF

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CN211433262U
CN211433262U CN201922186199.2U CN201922186199U CN211433262U CN 211433262 U CN211433262 U CN 211433262U CN 201922186199 U CN201922186199 U CN 201922186199U CN 211433262 U CN211433262 U CN 211433262U
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balloon
plastic tube
columnar
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annular plastic
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戴海龙
荆志成
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Abstract

The utility model discloses a freezing balloon catheter for treating clinical pulmonary hypertension, which comprises a handle, a functional base, a balloon catheter and a balloon working end, wherein the front end of the balloon catheter is connected with the balloon working end of an annular open loop, and the rear end of the balloon catheter is integrally formed with the functional base and the handle to control the balloon working end; the main body of the working end of the balloon is an annular plastic tube, an annular surface formed by the annular plastic tube is vertical to the axis of the balloon catheter, a columnar balloon is wrapped and installed on the annular plastic tube, and a reserved hole is formed in the front end of the annular plastic tube; through the design of cyclic annular pipe and column sacculus of can moulding, melt with less damage and higher laminating degree after pouring into cooling medium into, the cooling medium backward flow discharge that will pour into simultaneously according to the backward flow circulation of design is in order to increase to melt the effect, need not block the blood flow, can detect pulmonary artery pressure in the design of the front end preformed hole of sacculus work end simultaneously, its structural design is reasonable, convenient and practical, is fit for medical institution and popularizes and applies.

Description

Freezing balloon catheter for treating clinical pulmonary arterial hypertension
Technical Field
The utility model relates to a pulmonary artery high pressure treatment apparatus technical field, specificly relate to a freezing sacculus pipe for treating clinical pulmonary artery high pressure.
Background
Pulmonary hypertension is a type of vascular lesion mainly affecting pulmonary arterioles, and the pulmonary arterial pressure is increased progressively, so that the pulmonary circulatory hemodynamics of a patient are changed, pulmonary artery vascular remodeling, right heart hypertrophy and functional failure are main characteristics of the pulmonary arterial hypertension. The golden standard for diagnosing pulmonary hypertension is that the mean pulmonary artery pressure measured by a right heart catheter is more than or equal to 25mmHg under the sea level state and at rest, the pulmonary arteriolar wedge pressure is less than or equal to 15mmHg, and the pulmonary vascular resistance is more than 3Wood units. Experimental data prove that pulmonary hypertension is related to excitability increase of sympathetic nerves in pulmonary artery and abnormal activity of baroreceptors, and the pulmonary arterial pressure can be reduced by blocking the sympathetic nerves in the pulmonary artery or permanently destroying the structure and the function of the baroreceptors, so that the technology becomes a breakthrough technology for treating the pulmonary hypertension.
At present, the conventional radiofrequency ablation therapy is to release radiofrequency current to make tissue ions in vivo vibrate along the direction of current change, so that the tissue ions with the current function around the electrode rub against each other to generate heat, and the coagulation necrosis of the tissue is caused. The cryoablation is a new technology applied to atrial fibrillation treatment in recent years, and the technology utilizes the principle that liquid nitrous oxide is gasified to instantly absorb a large amount of heat, so that the temperature of cell tissues in contact with a cryoballoon can be reduced to-80 ℃ at the lowest, the cell tissues can generate irreversible damage, and the cell tissues can be replaced by fibrous tissues at the later stage.
The pulmonary artery pressure can be reduced by blocking sympathetic nerves in the pulmonary artery or permanently damaging the structure and the function of a pressure receptor, but the prior pulmonary artery radio frequency ablation catheter has the following defects: 1) the radio frequency ablation mode has the problems of great endangium damage, unstable catheter contact, thrombosis, pulmonary artery stenosis, point ablation and the like; 2) the resistance rise caused by overheating can cause barotrauma and perforation; 3) the existing radio frequency ablation catheter does not have a pulmonary artery pressure monitoring function and cannot monitor the pulmonary artery pressure in real time; 4) it is not easy to monitor the ablation temperature and the function of pulmonary artery nerve electrical signals. Cryoablation has the following advantages: 1) the normal structure of the tissue is not damaged, the intracellular ultrastructure is reserved, the damage to the surface of the blood vessel intima and the formation of mural thrombus are reduced, and the probability of operation-related complications such as embolism caused by pulmonary artery stenosis and thrombosis is greatly reduced theoretically; 2) because an ice ball is formed during freezing, the top end of the catheter is adhered with tissues (namely, frozen adhesion), so that the catheter has better stability and can effectively ablate; 3) perforation caused by burst of heat energy can not occur; 4) does not need a large amount of cold saline for perfusion, is very suitable for people with cardiac insufficiency, and avoids the occurrence of heart failure caused by excessive liquid entering the body; 5) a continuous, transmural ablation pathway can be achieved. Therefore, it is necessary to develop and design a cryoballoon catheter for treating clinical pulmonary hypertension.
SUMMERY OF THE UTILITY MODEL
The above-mentioned problem to prior art exists, the utility model provides a freezing sacculus pipe for treating clinical pulmonary artery is highly compressed blocks the structure and the function that sympathetic nerve or permanent destruction pressure sensor in the pulmonary artery and can make pulmonary artery pressure descend, can monitor pulmonary artery pressure simultaneously and do not influence blood circulation to possess freezing sacculus temperature monitoring function, and the neural signal of telecommunication monitoring function of pulmonary artery, be fit for popularizing and applying.
In order to realize the technical purpose, the technical effect is achieved, the utility model discloses a realize through following technical scheme:
a freezing balloon catheter for treating clinical pulmonary artery hypertension comprises a handle, a functional base, a balloon catheter and a balloon working end, wherein the front end of the balloon catheter is connected with the balloon working end of an annular open ring, and the functional base and the handle are integrally formed at the rear end to control the balloon working end;
the main body of the working end of the balloon is an annular plastic tube, the annular plastic tube is pre-shaped into a circular arc shape with an opening, an annular surface formed by the annular plastic tube is perpendicular to the axis of the balloon catheter, a cylindrical balloon is wrapped and installed on the annular plastic tube and does not reach the foremost end of the annular plastic tube, a reserved hole is formed in the front end of the annular plastic tube, and the reserved hole is connected to a handle at the rear end through a pressure measuring tube installed in the reserved hole to realize pulmonary artery pressure monitoring; the columnar saccule is divided into an outer side expansion part and an inner side expansion part according to the deformation strength, the deformation strength of the inner side expansion part is greater than that of the outer side expansion part, and the annular plastic pipes at the front end and the rear end of the columnar saccule are respectively provided with an air inlet hole and an air outlet hole and are respectively connected with an air inlet pipeline and an air outlet pipeline;
the inside of the balloon catheter is divided into four independent cavity channels which are respectively an air inlet pipeline, an exhaust pipeline, a pressure monitoring channel communicated with a preformed hole and a functional channel capable of reaching the front end of the annular plastic tube, the rear end of the balloon catheter is connected with a functional base, the upper side and the lower side of the functional base are respectively provided with an air inlet valve and an exhaust valve, the rear end of the functional base is a handle, and a detection base at the rear end of the handle is connected with a pressure monitoring unit and a functional unit.
Furthermore, a thermocouple temperature measuring wire extending into the columnar balloon is arranged in the functional energy channel, a functional unit connected with the rear end of the thermocouple temperature measuring wire is a temperature measuring unit, a detection unit of pulmonary artery nerve electrical signals can be arranged in the functional channel, and the pulmonary artery nerve electrical signals and the temperature of the freezing balloon are monitored in the operation process.
Furthermore, after the cylindrical saccule at the working end of the saccule is filled with a cooling medium, the annular plastic tube is close to one side of the inner expansion part by the column and deviates from the axis of the cylindrical saccule, the outer expansion part can be better attached to the wall of the blood vessel to play a role in cooling after being filled with the medium, the inner expansion wall does not need to block the blood flow, the deformation of the inner expansion wall is small, and the flow of the blood flow of the pulmonary artery is not influenced.
Furthermore, an air inlet hole of the columnar balloon is arranged on one side of the outer expansion part, and an air outlet hole is arranged on one side of the inner expansion part of the columnar balloon; considering that blood flows through the inner ring of the balloon working end, the exhaust hole is arranged at the position close to the inner side, and the cooling medium with the increased temperature is exhausted along with the situation;
the air inlet hole and the air outlet hole are respectively arranged on the front side or the rear side of the columnar saccule.
Further, the thickness of the outer expansion part of the columnar balloon is smaller than that of the inner expansion part.
Further, the sacculus work end main part is the annular plastic tube structure that opens and shuts, can shape out the annular that opens and shuts of different specifications, and the column sacculus that sets up also can laminate the vascular wall more at the inflation in-process.
Another object of the present invention is to provide a freezing balloon catheter for treating clinical pulmonary hypertension, which is applied to clinical pulmonary hypertension treatment.
The utility model has the advantages that: the utility model discloses a freezing sacculus pipe for treating clinical pulmonary artery high pressure, including handle, functional base, sacculus pipe and sacculus work end, sacculus pipe front end connects the sacculus work end of cyclic annular open loop, and rear end integrated into one piece functional base realizes controlling sacculus work end with the handle; the main body of the working end of the balloon is an annular plastic tube, an annular surface formed by the annular plastic tube is vertical to the axis of the balloon catheter, a columnar balloon is wrapped and installed on the annular plastic tube, and a reserved hole is formed in the front end of the annular plastic tube; through the design of the annular plastic tube and the cylindrical balloon, ablation is performed with smaller damage and higher fitting degree after cooling medium is injected, and meanwhile, the injected cooling medium is discharged in a backflow mode according to the designed backflow circulation so as to increase the ablation effect; more importantly, in the design scheme of the application, the columnar balloon aims to be attached to the vessel wall for ablation, the columnar balloon is slightly 90 degrees to the direction of blood flow in the vessel, the inner side expansion part has small deformation, the whole balloon is in an open-loop design, the size of the columnar balloon can be adjusted, meanwhile, the root part does not need to block the blood flow, the risk that the blood can only flow through the inner cavity of the catheter or is directly blocked after the traditional balloon is blocked is changed, and complications caused by similar problems are overcome; meanwhile, the design of the front end preformed hole at the working end of the balloon can detect the pulmonary artery pressure, and the balloon is reasonable in structural design, convenient and practical, and is suitable for popularization and application in medical institutions.
Of course, it is not necessary for any particular product to achieve all of the above-described advantages at the same time.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings used in the description of the embodiments will be briefly introduced below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art that other drawings can be obtained according to these drawings without creative efforts.
Fig. 1 is a schematic structural diagram of a freezing balloon catheter for treating clinical pulmonary hypertension according to an embodiment of the present invention;
fig. 2 is a schematic structural diagram of a balloon working end according to an embodiment of the present invention;
fig. 3 is a schematic structural diagram of a balloon working end according to an embodiment of the present invention;
fig. 4 is a third schematic structural view of the balloon working end according to the embodiment of the present invention;
fig. 5 is a schematic structural view of the handle and the functional base according to the embodiment of the present invention;
FIG. 6 is a schematic cross-sectional view taken along line A-A of FIG. 5 in accordance with the present invention;
in the drawings, the components represented by the respective reference numerals are listed below:
1-handle, 101-detection base, 2-function base, 201-air inlet valve, 202-air outlet valve, 3-balloon catheter, 4-balloon working end, 401-columnar balloon, 4011-inner expansion part, 4012-outer expansion part, 402-reserved hole, 4021-pressure measuring tube, 403-air inlet hole, 4031-air inlet pipeline, 404-air outlet hole, 4041 air outlet pipeline and 405-function channel.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by a person of ordinary skill in the art without creative efforts belong to the protection scope of the present invention.
Example 1
As shown in fig. 1-6
A freezing balloon catheter for treating clinical pulmonary hypertension comprises a handle 2, a functional base 2, a balloon catheter 3 and a balloon working end 4, wherein the front end of the balloon catheter 3 is connected with the balloon working end 4 of an annular open ring, and the functional base 2 and the handle 1 are integrally formed at the rear end to control the balloon working end 4;
the main body of the balloon working end 4 is an annular plastic tube, the annular plastic tube is pre-molded into an arc shape with an opening, an annular surface formed by the annular plastic tube is perpendicular to the axis of the balloon catheter 3, a cylindrical balloon 401 is wrapped and installed on the annular plastic tube, the cylindrical balloon 401 does not reach the foremost end of the annular plastic tube, a reserved hole 402 is formed in the front end of the annular plastic tube, and the reserved hole 402 is connected to the handle 1 at the rear end through a pressure measuring tube 4021 installed in the reserved hole to realize pulmonary artery pressure monitoring; the columnar balloon 401 is divided into an outer side expansion part 4012 and an inner side expansion part 4011 according to the deformation strength, the deformation strength of the inner side expansion part 4011 is greater than that of the outer side expansion part 4012, and the annular plastic pipes at the front end and the rear end of the columnar balloon 401 are respectively provided with an air inlet 403 and an air outlet 404 and are respectively connected with an air inlet pipe 4031 and an air outlet pipe 4041;
after the cylindrical sacculus 401 of sacculus working end 4 fills cooling medium, the annular can mould the pipe and lean on inboard expansion 4011 one side by the column, deviates the cylindrical sacculus 401 axle center, and laminating vascular wall that outside expansion 4012 can be better after filling into the medium plays the cooling effect, and inboard expansion 4011 also need not block the blood flow, and its deformation is little, and the flow of blood flow increases.
The air inlet hole 403 of the cylindrical balloon 401 is arranged at one side of the outer expansion part 4012, and the air outlet hole 404 is arranged at one side of the inner expansion part 4011 of the cylindrical balloon 401; considering that blood flows through the inner ring of the balloon working end 4, the exhaust holes 404 are arranged at the position close to the inner side to discharge the cooling medium with the increased temperature;
the air inlet hole 403 and the air outlet hole 404 are respectively arranged on the front side or the rear side of the cylindrical balloon 401.
The outer dilating portion 4012 of the cylindrical balloon 401 has a smaller thickness than the inner dilating portion 4011.
The balloon catheter 2 is internally divided into four independent channels, namely an air inlet channel 4031, an air outlet channel 4041, a pressure monitoring channel 4021 communicated with the preformed hole 402 and a functional channel 406 capable of reaching the front end of the annular plastic tube, the rear end of the balloon catheter 3 is connected with a functional base 2, an air inlet valve 201 and an air outlet valve 202 are respectively installed on the upper side and the lower side of the functional base 2, the rear end of the functional base 2 is a handle 1, and a detection base 101 at the rear end of the handle 1 is connected with a pressure monitoring unit and a functional unit.
A thermocouple temperature measuring wire extending into the columnar balloon 401 is arranged in the functional energy channel 406, a functional unit connected with the rear end of the thermocouple temperature measuring wire is a temperature measuring unit, a detection unit for pulmonary artery nerve electrical signals can be arranged in the functional channel 405, and the pulmonary artery nerve electrical signals and the temperature of the freezing balloon are monitored in the operation process.
The main body of the balloon working end 4 is an open-close annular plastic pipe structure, open-close rings with different specifications can be formed in a plastic mode, and the arranged columnar balloon 401 can be attached to a blood vessel wall better in the inflation process;
generally, the technical scheme of the application is as follows:
the structural design of the working end of the saccule, at first, by the annular open-close design perpendicular to the axis of the saccule conduit of the annular plastic tube, can carry on the circumferential expansion and laminating after inserting the blood vessel through the saccule conduit, the structural design of the column saccule that is adhered to, including inside expansion portion and outside expansion portion, in charging into the cooling medium process, the expansion effect of the outside expansion portion is better, make it more easy to laminate the vascular wall, and the design of the open loop can be more convenient to support and laminate, and the deformation degree of the inside expansion portion is smaller, make the blood flow of the inner ring flow through more easily, overcome the drawback of the existing saccule design and block the blood flow;
meanwhile, in the technical scheme of the application, different air inlets and air outlets are designed, and are respectively provided with a one-way valve, the cooling medium entering the cooling device acts immediately through the design of the air inlet close to the outer side expansion part, and the air outlet is arranged close to the inner side to discharge the cooling medium with increased temperature, so that the circulation of the cooling medium is realized;
finally, a preformed hole is designed on the working end of the balloon, and due to the fact that the position of the preformed hole is in contact with the flow of blood in the pulmonary artery, the preformed hole can be connected with an external pressure monitoring unit after passing through a piezometer tube to monitor the pulmonary artery pressure, and the monitoring of the pulmonary artery pressure is also the key of the application, and the purpose of cryoablation is to reduce the pulmonary artery high pressure; meanwhile, a thermocouple temperature measuring wire extending into the columnar saccule is arranged in the functional energy channel, so that the temperature of a freezing medium in the freezing saccule can be monitored in real time.
Example 2
The application of the freezing balloon catheter for treating clinical pulmonary hypertension in the clinical pulmonary hypertension treatment;
experimental data prove that pulmonary arterial hypertension is related to excitability increase of sympathetic nerves in pulmonary arteries and abnormal activity of baroreceptors, and the pulmonary arterial hypertension can be reduced by blocking the sympathetic nerves in the pulmonary arteries or permanently destroying the structure and the functions of the baroreceptors, so that the technology becomes a breakthrough technology for treating the pulmonary arterial hypertension;
based on the description and design of example 1, the design of the present application can be used for clinical pulmonary hypertension treatment;
the specific operation steps are the same as the existing cryoablation steps, after the balloon catheter is implanted, the media are filled into the cylindrical balloon, the filled cylindrical balloon is filled, and in the filling process, the expansion degree of the outer expansion part is greater than that of the inner expansion part, so that the outer expansion part is more easily attached to the blood vessel wall, and the blockage of the inner expansion part on the blood flow is reduced as much as possible;
after a certain amount of cooling medium is injected and stays for a certain period of time, in the process of continuing injecting, the pressure in the columnar saccule is increased, so that the cooling medium which stays for a period of time in the columnar saccule and has reduced temperature is discharged from the exhaust hole to ensure the freezing effect of the cooling medium in the columnar saccule;
detection of pulmonary artery pressure: the reserved hole is connected to a handle at the rear end through a piezometer tube arranged in the reserved hole to monitor the pulmonary artery pressure, and the pulmonary artery pressure can be monitored in the cryoablation process.
The utility model discloses a freezing sacculus pipe for treating clinical pulmonary artery is highly compressed blocks the structure and the function that sympathetic nerve or permanent destruction pressure sensor in the pulmonary artery and can make pulmonary artery pressure descend, can monitor pulmonary artery pressure simultaneously and do not influence blood circulation, is fit for popularizing and applying.
In the description herein, references to the description of "one embodiment," "an example," "a specific example," etc., mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the invention. In this specification, the schematic representations of the terms used above do not necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.
The preferred embodiments of the present invention disclosed above are intended only to help illustrate the present invention. The preferred embodiments are not intended to be exhaustive or to limit the invention to the precise embodiments disclosed. Obviously, many modifications and variations are possible in light of the above teaching. The embodiments were chosen and described in order to best explain the principles of the invention and its practical applications, to thereby enable others skilled in the art to best understand the invention for and utilize the invention. The present invention is limited only by the claims and their full scope and equivalents.

Claims (6)

1. A freezing balloon catheter for treating clinical pulmonary hypertension is characterized in that: the balloon catheter comprises a handle, a functional base, a balloon catheter and a balloon working end, wherein the front end of the balloon catheter is connected with the balloon working end of the annular open ring, and the functional base and the handle are integrally formed at the rear end to control the balloon working end;
the main body of the working end of the balloon is an annular plastic tube, the annular plastic tube is pre-shaped into a circular arc shape with an opening, an annular surface formed by the annular plastic tube is perpendicular to the axis of the balloon catheter, a cylindrical balloon is wrapped and installed on the annular plastic tube and does not reach the foremost end of the annular plastic tube, a reserved hole is formed in the front end of the annular plastic tube, and the reserved hole is connected to a handle at the rear end through a pressure measuring tube installed in the reserved hole to realize pulmonary artery pressure monitoring; the columnar saccule is divided into an outer side expansion part and an inner side expansion part according to the deformation strength, the deformation strength of the inner side expansion part is greater than that of the outer side expansion part, and the annular plastic pipes at the front end and the rear end of the columnar saccule are respectively provided with an air inlet hole and an air outlet hole and are respectively connected with an air inlet pipeline and an air outlet pipeline;
the inside of the balloon catheter is divided into four independent cavity channels which are respectively an air inlet pipeline, an exhaust pipeline, a pressure monitoring channel communicated with a preformed hole and a functional channel capable of reaching the front end of the annular plastic tube, the rear end of the balloon catheter is connected with a functional base, the upper side and the lower side of the functional base are respectively provided with an air inlet valve and an exhaust valve, the rear end of the functional base is a handle, and a detection base at the rear end of the handle is connected with a pressure monitoring unit and a functional unit.
2. A cryoballoon catheter for the treatment of clinical pulmonary hypertension according to claim 1, wherein: a thermocouple temperature measuring line extending into the columnar balloon is arranged in the functional energy channel, a functional unit connected with the rear end of the thermocouple temperature measuring line is a temperature measuring unit, a pulmonary artery nerve electrical signal detecting unit can be arranged in the functional channel, and monitoring of the pulmonary artery nerve electrical signal and monitoring of the temperature of the freezing balloon are carried out in the operation process.
3. A cryoballoon catheter for the treatment of clinical pulmonary hypertension according to claim 1, wherein: after the columnar saccule at the saccule working end is filled with the cooling medium, the annular plastic tube is close to one side of the columnar expansion part close to the inner side and deviates from the axis of the columnar saccule.
4. A cryoballoon catheter for the treatment of clinical pulmonary hypertension according to claim 1, wherein: the air inlet hole of the columnar balloon is arranged on one side of the outer side expansion part, and the air outlet hole is arranged on one side of the inner side expansion part of the columnar balloon;
the air inlet hole and the air outlet hole are respectively arranged on the front side or the rear side of the columnar saccule.
5. A cryoballoon catheter for the treatment of clinical pulmonary hypertension according to claim 1, wherein: the thickness of the outer expansion part of the columnar balloon is smaller than that of the inner expansion part.
6. A cryoballoon catheter for the treatment of clinical pulmonary hypertension according to claim 1, wherein: the sacculus work end main part is the annular plastic tube structure that opens and shuts, can shape out the annular that opens and shuts of different specifications, and the column sacculus that sets up also can laminate the vascular wall more at the inflation in-process.
CN201922186199.2U 2019-12-09 2019-12-09 Freezing balloon catheter for treating clinical pulmonary arterial hypertension Active CN211433262U (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111150482A (en) * 2019-12-09 2020-05-15 戴海龙 Freezing balloon catheter for treating clinical pulmonary arterial hypertension

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111150482A (en) * 2019-12-09 2020-05-15 戴海龙 Freezing balloon catheter for treating clinical pulmonary arterial hypertension
CN111150482B (en) * 2019-12-09 2024-07-12 戴海龙 Freezing saccule catheter for treating clinical pulmonary arterial hypertension

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