CN211274382U - High-efficient preparation facilities of styryl pyrrolidone amide with anticancer activity - Google Patents
High-efficient preparation facilities of styryl pyrrolidone amide with anticancer activity Download PDFInfo
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- CN211274382U CN211274382U CN201922051467.XU CN201922051467U CN211274382U CN 211274382 U CN211274382 U CN 211274382U CN 201922051467 U CN201922051467 U CN 201922051467U CN 211274382 U CN211274382 U CN 211274382U
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Abstract
The utility model provides a high-efficient preparation facilities of styryl pyrrolidone amide with anticancer activity includes the base and sets up compounding processing agency and the cooling and filtering mechanism on the base, compounding processing agency sets up in the top of base, the cooling and filtering mechanism sets up the lower extreme at compounding processing agency, this high-efficient preparation facilities of styryl pyrrolidone amide with anticancer activity includes base and compounding processing agency and the cooling and filtering mechanism of setting on the base, be provided with a plurality of groups on the well-being pivot of compounding processing agency and be vertical equidistance distribution's stirring rod, both sides on a plurality of groups of stirring rod all are provided with the stirring board, the stirring effect to the raw materials is better, in addition can heat it through the electrothermal tube, reach and heat stirring while heating, can improve the effect of mixing, and the raw materials liquid after mixing directly gets into the cooling shell and cools off and appears, and the preparation efficiency is also improved.
Description
Technical Field
The utility model relates to an amide derivative preparation technical field especially relates to the high-efficient preparation facilities of styryl pyrrolidone amide with anticancer activity.
Background
It is well known that functional molecules containing amide structural units are widely found in nature, and that amide units are also the main functional groups constituting the primary structure of proteins and polypeptides. Amide compounds have very important applications in the aspects of pharmaceutical chemistry, biochemistry, high polymer materials and the like, and various enzymes in the well-known life science field and high polymer materials and the like widely applied in daily life all contain a large number of amido bonds;
the effect of the high-efficient preparation facilities compounding that most have anti cancer activity's styryl pyrrolidone amide on the existing market is not good, can't prepare fast, consequently the utility model provides a problem that has the high-efficient preparation facilities of styryl pyrrolidone amide of anti cancer activity exists in order to solve prior art.
SUMMERY OF THE UTILITY MODEL
To the above problem, the utility model provides a high-efficient preparation facilities of styryl pyrrolidone amide with anticancer activity, this high-efficient preparation facilities of styryl pyrrolidone amide with anticancer activity includes the base and sets up compounding processing agency and the cooling and filtering mechanism on the base, the compounding processing agency is being provided with the stirring rod that a plurality of groups are vertical equidistance and distribute in the pivot, both sides on the stirring rod of a plurality of groups all are provided with the stirring board, stirring effect to the raw materials is better, can heat it through the electrothermal tube in addition, reach and heat stirring on one side, can improve the effect of mixing, and the raw materials liquid after mixing directly gets into in the cooling shell and cools off and appear, preparation efficiency is improved.
In order to solve the problems, the utility model provides a high-efficiency preparation device of styryl pyrrolidone amide with anticancer activity, which comprises a base, a mixed material processing mechanism and a cooling and filtering mechanism, wherein the mixed material processing mechanism and the cooling and filtering mechanism are arranged on the base;
the compounding processing agency is including a jar body and pivot, there is the low-speed motor jar body top through motor support fixed mounting, the pivot is installed to the output of low-speed motor, the one end of pivot runs through jar body and extends inside it, the feeding jar, both sides are all installed through the mount to the both sides outer wall of jar body the discharge gate fixed connection discharging pipe of feeding jar, the one end of discharging pipe runs through jar external wall and jar internal portion intercommunication, jar internal wall lower extreme is fixed with the heater casing, install a plurality of groups electrothermal tube in the heater casing.
The further improvement lies in that: the cooling and filtering mechanism comprises a heat insulation shell and a filter screen, the heat insulation shell is fixed on the base, a cooling shell is fixed in the heat insulation shell, a cooling plate is installed in the cooling shell, coolers are fixed at two ends below the cooling plate, two ends of the cooling plate are connected through an installation block between the coolers, the filter screen is installed on one side of the cooling shell through a filter screen support, a liquid outlet pipe is installed on the filter screen support, and one end of the liquid outlet pipe penetrates through the heat insulation shell and is provided with a liquid outlet valve.
The further improvement lies in that: the feeding device is characterized in that the feeding tank is provided with a cover plate, the cover plate is rotatably connected with the fixed block through a rotating shaft rod, the fixed block is fixed on the feeding tank, and the discharging pipe is provided with a discharging valve.
The further improvement lies in that: fixedly connected with a plurality of groups in the pivot are the stirring rod of vertical equidistance distribution, a plurality of groups both sides on the stirring rod all are provided with the stirring board.
The further improvement lies in that: the bottom in the jar body is for designing to central slope, and row's material pipe is installed at the center, arrange the lower extreme of material pipe and run through and separate temperature casing and cooling shell and install the bin outlet, arrange and install the relief valve on the material pipe, the external bottom both sides of jar are passed through the backup pad and are separated temperature casing fixed connection.
The further improvement lies in that: the heat insulation shell is characterized in that a heat insulation pad is fixedly mounted on the inner wall of the heat insulation shell, and a thermometer is arranged above the tank body.
The further improvement lies in that: the cooling device comprises a cooling shell, and is characterized in that a pulling plate is arranged on one side of the cooling shell, sliding rails are arranged on two sides of the pulling plate, the sliding rails are connected with sliding strips arranged in the side wall of the cooling shell in a sliding mode, a hydraulic cylinder is fixed in the middle of the pulling plate through a pulling block, and the bottom of the hydraulic cylinder is fixed on the cooling shell through a fixing plate.
The utility model has the advantages that: this high-efficient preparation facilities of styryl pyrrolidone amide with anticancer activity includes the base and sets up compounding processing agency and the cooling and filtering mechanism on the base, compounding processing agency is being provided with the stirring rod that a plurality of groups are vertical equidistance and distribute in the pivot, both sides on the stirring rod of a plurality of groups all are provided with the stirring board, stirring effect to the raw materials is better, can heat it through the electrothermal tube in addition, reach and heat stirring on one side, can improve the effect of mixing, and the raw materials liquid after mixing directly gets into and cools off in the cooling shell and separate out, preparation efficiency has still been improved.
Drawings
Fig. 1 is a front view of the present invention.
Fig. 2 is a front view of the cooling housing of the present invention.
Wherein: 1. a base; 2. a tank body; 3. a rotating shaft; 4. a motor bracket; 5. a low-speed motor; 6. a fixed mount; 7. a feed tank; 8. a heater housing; 9. an electric heating tube; 10. a heat-insulating shell; 11. a filter screen; 12. cooling the housing; 13. a cooling plate; 14. a cooler; 15. mounting blocks; 16. a screen support; 17. a liquid outlet pipe; 18. a liquid outlet valve; 19. a cover plate; 20. a fixed block; 21. a discharge valve; 22. a stirring rod; 23. a stirring plate; 24. a discharge pipe; 25. a discharge outlet; 26. a discharge valve; 27. a support plate; 28. a thermal insulation pad; 29. a thermometer; 30. pulling a plate; 31. a slide rail; 32. a slide bar; 33. pulling the block; 34. a hydraulic cylinder; 35. a fixing plate; 701. and (4) discharging the pipe.
Detailed Description
In order to deepen the understanding of the present invention, the following embodiments will be combined to make the present invention do further details, and the present embodiment is only used for explaining the present invention, and does not constitute the limitation of the protection scope of the present invention.
According to the fig. 1 and 2, the embodiment provides a high-efficiency preparation device of styryl pyrrolidone amide with anticancer activity, which comprises a base 1, and a mixed material processing mechanism and a cooling filtering mechanism which are arranged on the base 1, wherein the mixed material processing mechanism is arranged above the base 1, and the cooling filtering mechanism is arranged at the lower end of the mixed material processing mechanism;
in this embodiment, compounding processing agency is including a jar body 2 and pivot 3, there is low-speed motor 5 jar body 2 top through 4 fixed mounting of motor support, pivot 3 is installed to low-speed motor 5's output, the one end of pivot 3 runs through jar body 2 and extends inside it, feeding tank 7, both sides are all installed through mount 6 to jar body 2's both sides outer wall feeding tank 7's discharge gate fixed connection discharging pipe 701, discharging pipe 701's one end runs through jar body 2 outer wall and jar body 2 inside intercommunication, jar body 2 inner wall lower extreme is fixed with heater casing 8, install a plurality of groups electrothermal tube 9 in the heater casing 8.
In this embodiment, cooling filter mechanism is including separating temperature casing 10 and filter screen 11, separate temperature casing 10 and fix on base 1, separate temperature casing 10 internal fixation and have cooling casing 12, install cooling plate 13 in the cooling casing 12, cooling plate 13 below both ends all are fixed with cooler 14, both ends connect through installation piece 15 between the cooler 14, filter screen 11 is installed through filter screen support 16 in cooling casing 12 one side, install drain pipe 17 on filter screen support 16, the one end of drain pipe 17 is run through and is separated temperature casing 10 and be provided with drain valve 18.
In this embodiment, be equipped with apron 19 on the feed tank 7, apron 19 rotates through pivot stick and fixed block 20 to be connected, fixed block 20 is fixed on feed tank 7, both sides all be provided with bleeder valve 21 on the discharging pipe 701.
In this embodiment, fixedly connected with a plurality of groups is the stirring rod 22 that vertical equidistance distributes, a plurality of groups in the pivot 3 both sides on the stirring rod 22 all are provided with stirring board 23.
In this embodiment, the bottom in the tank body 2 is designed to be inclined towards the center, a material discharging pipe 24 is installed at the center, the lower end of the material discharging pipe 24 penetrates through the heat insulation shell 10 and the cooling shell 12 and is provided with a material discharging opening 25, a material discharging valve 26 is installed on the material discharging pipe 24, and two sides of the bottom outside the tank body 2 are fixedly connected with the heat insulation shell 10 through a supporting plate 27.
In this embodiment, a thermal insulation pad 28 is fixedly mounted on the inner wall of the thermal insulation casing 10, and a thermometer 29 is disposed above the tank body 2.
In this embodiment, one side of the cooling housing 12 is provided with a pulling plate 30, two sides of the pulling plate 30 are provided with slide rails 31, the slide rails 31 are slidably connected with slide bars 32 arranged in the side wall of the cooling housing 12, a hydraulic cylinder 34 is fixed in the middle of the pulling plate 30 through a pulling block 33, and the bottom of the hydraulic cylinder 34 is fixed on the cooling housing 12 through a fixing plate 35.
In the utility model, the material inlet pipe is respectively put into the material inlet tanks 7 at both sides, the material outlet valve 21 on the material outlet pipe 701 is opened, the raw material is put into and out of the tank body 2 by proportion, if the raw material is redundant, the material outlet valve 21 can be closed to store the raw material in the material inlet tank 7, the low-speed motor 5 and the electric heating pipe 9 are started, the rotating shaft 3 is rotated by the low-speed motor 5, a plurality of groups of stirring rods 22 which are distributed in vertical equidistance are arranged on the rotating shaft 3, the stirring plates 23 are arranged at both sides of the groups of stirring rods 22, the stirring effect on the raw material is good, in addition, the electric heating pipe 9 is internally heated and liquefied, the raw material is heated while being stirred, the raw material is rapidly and uniformly mixed, then, the mixed raw material liquid flows into the cooling shell 12 by opening the material outlet valve 26, the cooler 14 is started to, the liquid is discharged through the filter screen 11 by opening the liquid outlet valve 18, the crystalline solid is retained on the cooling plate 13 by the filter screen, and then the pulling plate 30 is pulled up by the hydraulic cylinder 34, and the amide derivative on the cooling plate 13 is manually collected.
The foregoing illustrates and describes the principles, general features, and advantages of the present invention. It will be understood by those skilled in the art that the present invention is not limited to the above embodiments, and that the foregoing embodiments and descriptions are provided only to illustrate the principles of the present invention without departing from the spirit and scope of the present invention. The scope of the invention is defined by the appended claims and equivalents thereof.
Claims (7)
1. High-efficient preparation facilities of styryl pyrrolidone amide with anticancer activity, its characterized in that: the automatic mixing machine comprises a base (1), and a mixing processing mechanism and a cooling filtering mechanism which are arranged on the base (1), wherein the mixing processing mechanism is arranged above the base (1), and the cooling filtering mechanism is arranged at the lower end of the mixing processing mechanism;
compounding processing agency is including a jar body (2) and pivot (3), there is low-speed motor (5) jar body (2) top through motor support (4) fixed mounting, pivot (3) are installed to the output of low-speed motor (5), the one end of pivot (3) runs through jar body (2) and extends inside it, feeding jar (7), both sides are all installed through mount (6) to the both sides outer wall of the jar body (2) the discharge gate fixed connection discharging pipe (701) of feeding jar (7), the one end of discharging pipe (701) runs through jar body (2) outer wall and jar body (2) inside intercommunication, jar body (2) inner wall lower extreme is fixed with heater casing (8), install a plurality of groups electrothermal tube (9) in heater casing (8).
2. The apparatus for efficiently preparing styryl pyrrolidone amide with anticancer activity as set forth in claim 1, wherein: cooling filter mechanism is including separating temperature casing (10) and filter screen (11), separate temperature casing (10) and fix on base (1), separate temperature casing (10) internal fixation and have cooling casing (12), install cooling plate (13) in cooling casing (12), cooling plate (13) below both ends all are fixed with cooler (14), both ends connect through installation piece (15) between cooler (14), filter screen (11) are installed through filter screen support (16) in cooling casing (12) one side, install drain pipe (17) on filter screen support (16), the one end of drain pipe (17) is run through and is separated temperature casing (10) and be provided with drain valve (18).
3. The apparatus for efficiently preparing styryl pyrrolidone amide with anticancer activity as set forth in claim 1, wherein: be equipped with apron (19) on feeding tank (7), apron (19) are rotated through pivot stick and fixed block (20) and are connected, fixed block (20) are fixed on feeding tank (7), both sides all be provided with bleeder valve (21) on discharging pipe (701).
4. The apparatus for efficiently preparing styryl pyrrolidone amide with anticancer activity as set forth in claim 1, wherein: the utility model discloses a stirring rod, including pivot (3), fixedly connected with a plurality of groups are stirring rod (22) that vertical equidistance distributes, a plurality of groups both sides on stirring rod (22) all are provided with stirring board (23).
5. The apparatus for efficiently preparing styryl pyrrolidone amide with anticancer activity as set forth in claim 1, wherein: the bottom in the jar body (2) is for to the design of central slope, and row material pipe (24) are installed at the center, the lower extreme of arranging material pipe (24) runs through and separates temperature casing (10) and cooling housing (12) and install bin outlet (25), install relief valve (26) on arranging material pipe (24), the outer bottom both sides of jar body (2) are passed through backup pad (27) and are separated temperature casing (10) fixed connection.
6. The apparatus for efficiently preparing styryl pyrrolidone amide with anticancer activity as set forth in claim 2, wherein: a heat insulation pad (28) is fixedly arranged on the inner wall of the heat insulation shell (10), and a thermometer (29) is arranged above the tank body (2).
7. The apparatus for efficiently preparing styryl pyrrolidone amide with anticancer activity as set forth in claim 2, wherein: one side of cooling casing (12) is provided with arm-tie (30), the both sides of arm-tie (30) are provided with slide rail (31), slide rail (31) and setting up draw bar (32) sliding connection in cooling casing (12) lateral wall, be fixed with pneumatic cylinder (34) through drawing piece (33) in the middle of arm-tie (30), the bottom of pneumatic cylinder (34) is passed through fixed plate (35) and is fixed on cooling casing (12).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201922051467.XU CN211274382U (en) | 2019-11-25 | 2019-11-25 | High-efficient preparation facilities of styryl pyrrolidone amide with anticancer activity |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201922051467.XU CN211274382U (en) | 2019-11-25 | 2019-11-25 | High-efficient preparation facilities of styryl pyrrolidone amide with anticancer activity |
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| CN211274382U true CN211274382U (en) | 2020-08-18 |
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| CN201922051467.XU Active CN211274382U (en) | 2019-11-25 | 2019-11-25 | High-efficient preparation facilities of styryl pyrrolidone amide with anticancer activity |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113999154A (en) * | 2021-06-23 | 2022-02-01 | 国药东风总医院 | Compound and preparation method and application thereof |
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2019
- 2019-11-25 CN CN201922051467.XU patent/CN211274382U/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113999154A (en) * | 2021-06-23 | 2022-02-01 | 国药东风总医院 | Compound and preparation method and application thereof |
| CN113999154B (en) * | 2021-06-23 | 2023-03-21 | 国药东风总医院 | Compound and preparation method and application thereof |
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