CN211216197U - Granular sodium hyaluronate production equipment - Google Patents
Granular sodium hyaluronate production equipment Download PDFInfo
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- CN211216197U CN211216197U CN201921910665.0U CN201921910665U CN211216197U CN 211216197 U CN211216197 U CN 211216197U CN 201921910665 U CN201921910665 U CN 201921910665U CN 211216197 U CN211216197 U CN 211216197U
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- sodium hyaluronate
- stirring shaft
- production equipment
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Abstract
The to-be-solved problem of the utility model is to provide a material in the intensive mixing production jar improves production efficiency's graininess sodium hyaluronate production facility, including production jar and (mixing) shaft, still including control the (mixing) shaft is in rotatory, lateral shifting and the drive control device who reciprocates in the production jar.
Description
Technical Field
The utility model relates to a sodium hyaluronate production field, concretely relates to graininess sodium hyaluronate production facility.
Background
Sodium hyaluronate (Hyaluronic acid. HA) is a linear high molecular viscous polysaccharide with repeating units formed by beta-D-glucuronic acid and N-acetylglucosamine through beta.1-3 and beta.1-4 glycosidic bonds, and HAs the functions of retaining water, lubricating and regulating osmotic pressure. Is widely applicable to the industries of orthopedics, ophthalmology and cosmetics, and has wide market prospect.
The existing sodium hyaluronate product is mainly in a powder and particle state. The granular sodium hyaluronate has short dissolving time, less dust production, no caking during dissolving and good dispersibility. Through contrast experiment, the dissolution time of the granular sodium hyaluronate is shortened by half, and the dissolution effect and the dispersibility are good. The preparation of the sodium hyaluronate particles is that the sodium hyaluronate fermentation liquor is precipitated by alcohol, and then the obtained precipitate is dissolved and purified by the working procedures of alkaline hydrolysis, filtration and the like. And carrying out the processes of precipitation, washing, granulation, dehydration, drying and the like on the purified solution to finally obtain the sodium hyaluronate product. The precipitate after the secondary precipitation is in a soft state, and is fully washed under the stirring action of the spiral blades by adding washing alcohol. As the number of washes increases, the precipitate hardens to meet the requirements of obtaining a granular product. However, the stirring shaft in the existing production equipment can only rotate forwards or backwards in a speed-adjustable manner, and materials at the bottom and the side wall of the production tank are not easy to stir, so that the production efficiency is low.
SUMMERY OF THE UTILITY MODEL
The to-be-solved problem of the utility model is to provide a material in the intensive mixing production jar improves production efficiency's graininess sodium hyaluronate production facility.
The utility model discloses a realize through following technical scheme:
the granular sodium hyaluronate production equipment comprises a production tank, a stirring shaft and a driving control device for controlling the stirring shaft to rotate, transversely move and move up and down in the production tank.
Further, the driving control device comprises a rotary driving device, a lifting device and a transverse moving device.
Further, the rotary driving device comprises an upper connecting plate, a driving motor, a driving sprocket and a driven sprocket, the stirring shaft is vertically installed at one end of the upper connecting plate through a bearing assembly, the upper end of the stirring shaft is fixedly connected with the driven sprocket, the driving motor is installed at the other end of the upper connecting plate, the driving sprocket is installed on an output shaft of the driving motor, and the driving sprocket and the driven sprocket are driven through a chain; the lower part of the upper connecting plate is arranged on the lifting device, and the lifting device is arranged on the transverse moving device.
Furthermore, elevating gear includes bed plate and at least one pneumatic cylinder, and the piston rod fixed connection of pneumatic cylinder the lower part of upper junction plate, the bed plate fixed connection is in the bottom of pneumatic cylinder.
Furthermore, the transverse moving device comprises a sliding rail, a sliding block seat and an electric screw, the sliding block seat is in sliding fit with the sliding rail, the upper end face of the sliding block seat is fixedly connected with the base plate, and the movable end of the electric screw is connected with the sliding block seat.
Furthermore, a detachable upper cover body is installed on the upper portion of the production tank, and the transverse moving device is installed on the upper cover body.
Furthermore, the stirring shaft is a spiral stirring paddle, the transverse movement frequency of the stirring shaft is 2-3 times per minute, and the up-down movement frequency of the stirring shaft is 5-6 times per minute.
Compared with the prior art, the utility model the beneficial effect who gains as follows:
1. in the process that the stirring shaft stirs the sodium hyaluronate in the production tank, the lifting device can control the stirring shaft to move up and down, so that the materials close to the bottom can be fully stirred, the transverse moving device can control the stirring shaft to move transversely, so that the materials close to the side wall can be fully stirred, the materials in the production tank can be fully and uniformly stirred, and the production efficiency is greatly improved;
2. the utility model discloses simple structure, easy maintenance, operation use are convenient.
Drawings
Fig. 1 is a schematic view of the three-dimensional structure of the granular sodium hyaluronate production equipment of the present invention;
FIG. 2 is a schematic view of the internal structure of the granular sodium hyaluronate production equipment of the present invention;
fig. 3 is a schematic view of a three-dimensional structure of the driving control device of the present invention;
in the figure: 1. production jar, 2, (mixing) shaft, 3, upper cover body, 4, upper junction plate, 5, driving motor, 6, bed plate, 7, pneumatic cylinder, 8, slide rail, 9, slider seat, 10, electronic screw rod.
Detailed Description
The technical solutions in the embodiments of the present application will be described clearly and completely with reference to the drawings in the embodiments of the present application, and it is obvious that the described embodiments are only a part of the embodiments of the present application, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments of the present application without making any creative effort, shall fall within the protection scope of the present application.
The production equipment for granular sodium hyaluronate shown in fig. 1-3 mainly comprises a production tank 1 with volume of 1000L, a stirring shaft 2, an upper cover body 3, a rotary driving device for controlling the stirring shaft to rotate, a lifting device for controlling the stirring shaft to move up and down, and a transverse moving device for controlling the stirring shaft to move transversely. The (mixing) shaft selects the spiral stirring rake commonly used, goes up the lid and passes through the mode of bolt fastening and install the upper portion open end at the production jar, is equipped with the slot hole on the upper cover body 3 to the (mixing) shaft stretches into and can lateral shifting.
Wherein, rotary driving device includes upper junction plate 4, driving motor 5, drive sprocket and driven sprocket, (mixing) shaft 2 is close to the position of upper end and passes through the bearing assembly vertical to installing the right-hand member at upper junction plate 4, (mixing) shaft 2's upper end is through flat key fixed connection driven sprocket, and driving motor 5 passes through the bolt and installs the left end at upper junction plate 4, install drive sprocket on driving motor 5's the output shaft, drive sprocket and driven sprocket pass through chain drive, and driving motor 5 can drive the rotatory stirring shaft that stirs through sprocket drive like this.
The lifting device comprises a base plate 6 and four hydraulic cylinders 7, the bottoms of the four hydraulic cylinders 7 are fixed on the base plate 6 through bolts, piston rods of the four hydraulic cylinders 7 are fixedly connected with the lower part of the upper connecting plate 4 together, and the upper connecting plate 4 is controlled to move up and down through a hydraulic pump.
The transverse moving device comprises a sliding rail 8, a sliding block seat 9 and an electric screw 10, the sliding rail 8 is fixed on the upper cover body 3 through a bolt, the sliding block seat 9 is in sliding fit with the sliding rail 8, the upper end face of the sliding block seat 9 is fixedly connected with the base plate 6 through a bolt, the electric screw 10 is installed on the upper cover body 3, and the movable end of the electric screw 10 is connected with the sliding block seat 9.
Taking sodium hyaluronate washing pelletization process as an example, the specific working process of granular sodium hyaluronate production equipment is as follows:
adding washing alcohol into the sodium hyaluronate precipitate in a production tank, stirring by a stirring shaft in an up-and-down and transverse moving mode, stirring at 10-50rpm for 10min, standing for 20min, stirring at 50-100rpm for 10min, standing for 30-60min, repeating the operation for 2-5 times, and standing for 60-360min, wherein in the process, the transverse moving frequency of the stirring shaft 2 is 2 times per minute, and the up-and-down moving frequency of the stirring shaft 2 is 6 times per minute. And (4) treating the washed precipitate by a homogenizing pump, dehydrating and drying to obtain a granular product. The stirring of the materials in the production tank is fully and uniformly realized, and the production efficiency is greatly improved.
Claims (7)
1. The granular sodium hyaluronate production equipment comprises a production tank and a stirring shaft, and is characterized by further comprising a driving control device for controlling the stirring shaft to rotate, transversely move and move up and down in the production tank.
2. The granular sodium hyaluronate production equipment according to claim 1, wherein the drive control device comprises a rotary drive device, a lifting device and a transverse moving device.
3. The granular sodium hyaluronate production equipment according to claim 2, wherein the rotary driving device comprises an upper connecting plate, a driving motor, a driving sprocket and a driven sprocket, the stirring shaft is vertically mounted at one end of the upper connecting plate through a bearing assembly, the upper end of the stirring shaft is fixedly connected with the driven sprocket, the driving motor is mounted at the other end of the upper connecting plate, the driving sprocket is mounted on an output shaft of the driving motor, and the driving sprocket and the driven sprocket are driven by a chain; the lower part of the upper connecting plate is arranged on the lifting device, and the lifting device is arranged on the transverse moving device.
4. The granular sodium hyaluronate production equipment according to claim 3, wherein the lifting device comprises a base plate and at least one hydraulic cylinder, a piston rod of the hydraulic cylinder is fixedly connected with the lower part of the upper connecting plate, and the base plate is fixedly connected with the bottom of the hydraulic cylinder.
5. The granular sodium hyaluronate production equipment according to claim 4, wherein the transverse moving device comprises a sliding rail, a sliding block seat and an electric screw, the sliding block seat is slidably fitted on the sliding rail, the upper end face of the sliding block seat is fixedly connected with the base plate, and the movable end of the electric screw is connected with the sliding block seat.
6. The granular sodium hyaluronate production equipment according to claim 5, wherein a detachable upper cover body is mounted on the upper part of the production tank, and the transverse moving device is mounted on the upper cover body.
7. The granular sodium hyaluronate production equipment according to any one of claims 1 to 6, wherein the stirring shaft is a helical stirring paddle, the transverse movement frequency of the stirring shaft is 2-3 times per minute, and the up-and-down movement frequency of the stirring shaft is 5-6 times per minute.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201921910665.0U CN211216197U (en) | 2019-11-07 | 2019-11-07 | Granular sodium hyaluronate production equipment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201921910665.0U CN211216197U (en) | 2019-11-07 | 2019-11-07 | Granular sodium hyaluronate production equipment |
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| Publication Number | Publication Date |
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| CN211216197U true CN211216197U (en) | 2020-08-11 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201921910665.0U Active CN211216197U (en) | 2019-11-07 | 2019-11-07 | Granular sodium hyaluronate production equipment |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112961754A (en) * | 2021-02-25 | 2021-06-15 | 甘肃傲农饲料科技有限公司 | Production system and production method of soybean meal fermented feed additive |
-
2019
- 2019-11-07 CN CN201921910665.0U patent/CN211216197U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112961754A (en) * | 2021-02-25 | 2021-06-15 | 甘肃傲农饲料科技有限公司 | Production system and production method of soybean meal fermented feed additive |
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