CN211042530U - Biological sample low temperature transfer car (buggy) - Google Patents

Biological sample low temperature transfer car (buggy) Download PDF

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Publication number
CN211042530U
CN211042530U CN201921735759.9U CN201921735759U CN211042530U CN 211042530 U CN211042530 U CN 211042530U CN 201921735759 U CN201921735759 U CN 201921735759U CN 211042530 U CN211042530 U CN 211042530U
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liquid nitrogen
temperature
control unit
transfer car
buggy
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CN201921735759.9U
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滕培坤
刘承党
刘润东
陈海涛
刘占杰
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Qingdao Haier Biomedical Co Ltd
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Qingdao Haier Biomedical Co Ltd
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Abstract

The utility model discloses a biological sample low temperature transfer car (buggy), including the automobile body, be equipped with the liquid nitrogen jar in it, the intracavity that holds of automobile body is equipped with the liquid nitrogen and adsorbs the cotton, and the liquid nitrogen in the liquid nitrogen jar can spray the liquid nitrogen through pipeline and adsorb the cotton on, be equipped with the control valve on the pipeline, hold the intracavity and be equipped with and freeze box and temperature sensor. The user can input a set temperature required for storing the biological sample on the operation display unit, and the operation display unit uploads the set temperature to the analysis control unit. The temperature sensor uploads the detected temperature information to the analysis control unit. The analysis control unit controls the opening or closing of the control valve according to the temperature information and the set temperature so as to spray an appropriate amount of liquid nitrogen in the liquid nitrogen tank onto the liquid nitrogen adsorption cotton. When the temperature sensor detects that the temperature reaches the set temperature, the control valve is closed, and the liquid nitrogen stops being sprayed. The scheme can meet the requirements of different storage temperatures of different biological samples, ensure the biological activity of the biological samples and avoid the waste of liquid nitrogen.

Description

Biological sample low temperature transfer car (buggy)
Technical Field
The utility model relates to a biological medicine equipment technical field especially relates to a biological sample low temperature transfer car (buggy).
Background
In the biomedical industry, prepared biological samples, such as cells, need to be transferred and stored in cryogenic environments to preserve their biological activity. Biological samples such as cells are usually stored in a freezing tube, and a certain number of freezing tubes are put into a freezing box. During the transportation of the cryopreservation box, a deep low temperature environment needs to be maintained to ensure the biological activity of the biological sample. In the prior art, liquid nitrogen is directly injected into a transfer platform, and the liquid nitrogen is volatilized and cooled to obtain a deep low-temperature environment. Utilize the volatile cooling mode of liquid nitrogen, owing to lack the monitoring of liquid nitrogen volume, if the use of low temperature transportation platform exceeds certain time then can cause the temperature to rise because of lacking the liquid nitrogen, if use be less than certain time then can cause the waste of liquid nitrogen. Different temperature environments cannot be prepared according to different biological samples, the temperature in the transfer platform cannot be monitored in real time, and the biological activity of the biological samples is influenced.
The above information disclosed in this background section is only for enhancement of understanding of the background of the application and therefore it may comprise prior art that does not constitute known to a person of ordinary skill in the art.
Disclosure of Invention
In view of this, the utility model provides a biological sample low temperature transfer car (buggy), analysis and control unit sets up the temperature and detects the temperature according to the system, controls the liquid nitrogen jar and sprays right amount liquid nitrogen to the liquid nitrogen adsorbs on the cotton to satisfy the different storage temperature requirements of different biological samples, ensure biological activity of biological sample.
In order to realize the purpose of the utility model, the utility model adopts the following technical scheme to realize:
a biological sample low-temperature transfer trolley comprises a trolley body, wherein the trolley body is provided with a containing cavity with an upper opening; further comprising: the liquid nitrogen tank is arranged in the vehicle body; the liquid nitrogen adsorption cotton is arranged in the accommodating cavity, and liquid nitrogen in the liquid nitrogen tank can be sprayed onto the liquid nitrogen adsorption cotton through a conveying pipeline; the control valve is arranged on the conveying pipeline; the freezing storage box is arranged in the accommodating cavity and is close to the liquid nitrogen adsorption cotton, and the freezing storage box is used for storing biological samples; the temperature sensor is arranged in the accommodating cavity; an operation display unit on which a user can input a set temperature; the analysis control unit, the control valve with temperature sensor all with analysis control unit electricity is connected, temperature sensor uploads the temperature information that detects to analysis control unit, analysis control unit will receive temperature information uploads to operation display unit, operation display unit will the temperature information shows, operation display unit will set for the temperature upload to analysis control unit, analysis control unit according to the temperature information with set for the temperature controls opening or closing of control valve.
Furthermore, the vehicle body comprises a vehicle body and a heat insulator arranged on the upper part of the vehicle body, the heat insulator comprises a heat insulation bottom wall and a heat insulation side wall connected with the heat insulation bottom wall, and the heat insulator encloses the accommodating cavity; the liquid nitrogen container is arranged inside the vehicle body, the liquid nitrogen adsorption cotton is arranged at the bottom of the accommodating cavity, and the freezing storage box is arranged at the upper part of the liquid nitrogen adsorption cotton.
Furthermore, the bottom of the containing cavity is provided with a liquid nitrogen cavity for placing the liquid nitrogen adsorption cotton.
Further, the method also comprises the following steps: and the freezing frame is close to the liquid nitrogen cavity, and the freezing box is arranged in the freezing frame.
Furthermore, the heat insulation body is a vacuum heat insulation layer.
Furthermore, a cold guide plate is arranged on one side, facing the containing cavity, of the heat-preservation side wall, and the lower end of the cold guide plate is tightly attached to the upper surface of the liquid nitrogen cavity.
Furthermore, be located freeze and deposit the frame top hold the intracavity and be equipped with the operation bracket, the operation bracket includes the bracket body and locates the turn-ups of bracket body both sides, the bracket body is used for placing freeze and deposit the box.
Furthermore, the flanging is movably overlapped with the upper end of the cold guide plate.
Further, the temperature sensor is arranged above the liquid nitrogen cavity.
Furthermore, the upper part of the accommodating cavity is provided with a door body which can be opened and closed.
Compared with the prior art, the utility model discloses an advantage is with positive effect:
the user can input a set temperature required for storing the biological sample on the operation display unit, and the operation display unit uploads the set temperature to the analysis control unit. The temperature sensor uploads the detected temperature information to the analysis control unit, and the operation display unit can display the temperature information. The analysis control unit controls the opening or closing of the control valve according to the temperature information and the set temperature so as to spray a proper amount of liquid nitrogen in the liquid nitrogen tank onto the liquid nitrogen adsorption cotton through the conveying pipeline and reduce the temperature in the containing cavity through volatilization of the liquid nitrogen. When the temperature sensor detects that the temperature in the accommodating cavity reaches the set temperature, the control valve is closed, and the liquid nitrogen stops being sprayed. The scheme can meet the requirements of different storage temperatures of different biological samples, ensure the biological activity of the biological samples and avoid the waste of liquid nitrogen.
Other features and advantages of the present invention will become more apparent from the following detailed description of the invention when read in conjunction with the accompanying drawings.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings needed to be used in the description of the embodiments or the prior art will be briefly described below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without inventive labor.
FIG. 1 is a schematic structural view of an embodiment of the low-temperature transfer trolley for biological samples of the present invention;
FIG. 2 is an enlarged view of portion A of FIG. 1;
FIG. 3 is a schematic cross-sectional view of the embodiment of the low-temperature transfer trolley for biological samples of the present invention;
fig. 4 is a schematic view of the biological sample low-temperature transfer vehicle according to the embodiment of the present invention.
The system comprises a vehicle body 100, a vehicle body 110, a vehicle body 111, universal wheels 120, a heat insulation body 121, a heat insulation bottom wall 122, a heat insulation side wall 130, a containing cavity 140, a door body 150, a liquid nitrogen tank 200, a liquid nitrogen cavity 210, liquid nitrogen adsorption cotton 220, a conveying pipeline 230, a control valve 300, a freezing frame 400, a freezing box 500, an operation bracket 510, a bracket body 520, a flanging 600, a cold guide plate 600, a temperature sensor 700, an analysis control unit 800 and an operation display unit 900.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, but not all, embodiments of the present invention. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative efforts belong to the protection scope of the present invention.
It should be noted that in the description of the present invention, the terms of direction or positional relationship indicated by the terms "upper", "lower", "left", "right", "inner", "outer", etc. are based on the directions or positional relationships shown in the drawings, which are only for convenience of description, and do not indicate or imply that the device or element must have a specific orientation, be constructed and operated in a specific orientation, and thus, should not be construed as limiting the present invention.
The utility model discloses a biological sample low temperature transfer car (buggy), refer to fig. 1 and 3, including automobile body 100, the bottom of automobile body 100 is equipped with universal wheel 111 to the removal of transfer car (buggy) is convenient for. The vehicle body 100 is formed with an upper-opened receiving chamber 130 therein. Be equipped with liquid nitrogen container 150 in the automobile body 100, hold and be equipped with liquid nitrogen in the chamber 130 and adsorb cotton 210, liquid nitrogen in the liquid nitrogen container 150 can spray on liquid nitrogen adsorbs cotton 210 through transfer line 220, adsorbs on cotton 210 through liquid nitrogen and goes up the volatilization of liquid nitrogen and reduce the temperature that holds in the chamber 130, reaches the required low temperature environment of biological sample storage. The delivery pipe 220 is provided with a control valve 230, and the injection of liquid nitrogen is controlled by opening or closing the control valve 230. The accommodating cavity 130 is internally provided with a freezing storage box 400 for storing biological samples, which is close to the liquid nitrogen adsorption cotton 210 so as to fully absorb and utilize the cold energy at the position of the liquid nitrogen adsorption cotton 210. A temperature sensor 700 is further disposed in the accommodating chamber 130 for detecting the temperature in the accommodating chamber 130. The biological sample cryogenic transfer vehicle further includes an operation display unit 900 and an analysis control unit 800, referring to fig. 4. The user may input a set temperature required for the storage of the biological sample on the operation display unit 900. The control valve 230 and the temperature sensor 700 are electrically connected to the analysis control unit 800, the temperature sensor 700 uploads the detected temperature information to the analysis control unit 800, the analysis control unit 800 uploads the received temperature information to the operation display unit 900, and the operation display unit 900 displays the temperature information, so that the user can know the storage temperature of the biological sample in the accommodating chamber 130 in real time. The operation display unit 900 simultaneously uploads the set temperature to the analysis control unit 800, and the analysis control unit 800 controls the opening or closing of the control valve 230, that is, controls the injection of liquid nitrogen, according to the received temperature information and the set temperature. When the temperature sensor 700 detects that the temperature in the accommodating cavity 130 is lower than the set temperature, the control valve 230 is opened, liquid nitrogen is sprayed onto the liquid nitrogen adsorption cotton 210, the liquid nitrogen is volatilized and cooled, and the temperature in the accommodating cavity 130 is gradually reduced. When the temperature sensor 700 detects that the temperature inside the accommodating chamber 130 reaches the set temperature, the control valve 230 is closed and the liquid nitrogen stops being injected. The scheme can meet the requirements of different storage temperatures of different biological samples, ensure the biological activity of the biological samples and avoid the waste of liquid nitrogen.
Specifically, vehicle body 100 includes a vehicle body 110 and a heat insulator 120 provided on the upper portion of vehicle body 110, universal wheels 111 are provided on the bottom of vehicle body 110, and a liquid nitrogen tank 150 is provided inside vehicle body 110. The heat insulation body 120 comprises a heat insulation bottom wall 121 and a heat insulation side wall 122 connected with the heat insulation bottom wall 121, and the heat insulation body 120 encloses a containing cavity 130 with an upper opening. The liquid nitrogen adsorption cotton 210 is arranged at the bottom of the accommodating cavity 130, and the freezing storage box 400 is arranged at the upper part of the liquid nitrogen adsorption cotton 210. The liquid nitrogen in the liquid nitrogen adsorption cotton 210 volatilizes to generate cold energy, so that the temperature in the accommodating cavity 130 is reduced. The heat insulator 120 can prevent the cold energy in the accommodating cavity 130 from exchanging heat with the outside, so that the low-temperature environment in the accommodating cavity 130 can be kept for a longer time, and the transportation requirement of the biological sample can be met.
Preferably, a liquid nitrogen chamber 200 for placing the liquid nitrogen adsorption cotton 210 is arranged at the bottom of the accommodating chamber 130, and the liquid nitrogen adsorption cotton 210 is filled in the liquid nitrogen chamber 200. The upper portion in liquid nitrogen chamber 200 is equipped with freezes deposits frame 300, freezes deposits frame 300 and places in holding chamber 130, and a plurality of freezes deposits box 400 and locates in freezing deposits frame 300. The freezing storage box 400 is sequentially stacked in the freezing storage frame 300, and the freezing storage box 400 can be taken out of the freezing storage frame 300, so that the freezing storage tubes in the freezing storage box 400 can be operated conveniently. The freezing frame 300 is tightly close to the upper surface of the liquid nitrogen cavity 200 so as to fully absorb and utilize the cold energy at the liquid nitrogen cavity 200.
Preferably, the temperature sensor 700 is disposed above the liquid nitrogen chamber 200 and near the cryopreservation rack 300 to improve the accuracy of temperature detection, so that the temperature detected by the temperature sensor 700 is the temperature for storing the biological sample.
Preferably, the heat insulating body 120 is a vacuum heat insulating layer, which has a good heat insulating effect and reduces cold loss.
The upper portion that holds chamber 130 is equipped with the door body 140 that can open and shut, and when need not holding the biological sample in the chamber 130 and operating, door body 140 is closed, and the upper portion opening that will hold chamber 130 is sealed, avoids cold volume to run off. When the biological sample in the accommodating cavity 130 needs to be operated, the door body 140 is opened, and the upper opening of the accommodating cavity 130 is opened. In this embodiment, a magnetic attraction device (not shown) is disposed on the door 140, and when the door 140 is opened, the door 140 is attracted to the outer side of the thermal insulation sidewall 122 by the magnetic attraction device, so as to facilitate operation and reduce the space occupied by the door 140.
The side of the heat-preserving side wall 122 facing the accommodating cavity 130 is provided with a cold conducting plate 600, and the lower end of the cold conducting plate 600 is tightly attached to the upper surface of the liquid nitrogen cavity 200. Cold volume in the liquid nitrogen chamber 200 will transmit to leading cold plate 600 rapidly on, lead cold plate 600 with cold volume spread rapidly to holding in the chamber 130 for hold the cooling rate in the chamber 130, be favorable to biological sample's storage more. In this embodiment, the number of the cold conducting plates 600 is two, and the two cold conducting plates are symmetrically disposed on the two longer heat preservation sidewalls 122. In other embodiments, the number of the cold guide plates 600 may be flexibly set according to the size of the accommodating chamber 130.
Referring to fig. 1 and 2, an operation bracket 500 is arranged in the accommodating cavity 200 above the cryopreservation rack 300, the operation bracket 500 comprises a bracket body 510 and flanges 520 arranged at two sides of the bracket body 510, and the bracket body 510 is used for placing the cryopreservation box 400. When the small-batch cryopreservation box 400 needs to be operated, the cryopreservation box 400 is placed on the bracket body 510 for sorting and other operations, so that the biological sample is always in the low-temperature environment of the accommodating cavity 130, the temperature rise of the biological sample is avoided, and the biological activity of the biological sample is ensured.
Preferably, the flange 520 is movably engaged with the upper end of the cold guide plate 600 so that the placing position of the operating bracket 500 is not fixed but movable to prevent the operating bracket 500 from interfering with the taking and storing operations of the lower freezing box 400.
Finally, it should be noted that: the above embodiments are only used to illustrate the technical solution of the present invention, and not to limit it; although the present invention has been described in detail with reference to the foregoing embodiments, it should be understood by those skilled in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some technical features may be equivalently replaced; such modifications and substitutions do not depart from the spirit and scope of the present invention in its corresponding aspects.

Claims (10)

1. A biological sample low-temperature transfer trolley comprises a trolley body and is characterized in that,
the vehicle body is provided with an accommodating cavity with an upper opening;
further comprising:
the liquid nitrogen tank is arranged in the vehicle body;
the liquid nitrogen adsorption cotton is arranged in the accommodating cavity, and liquid nitrogen in the liquid nitrogen tank can be sprayed onto the liquid nitrogen adsorption cotton through a conveying pipeline;
the control valve is arranged on the conveying pipeline;
the freezing storage box is arranged in the accommodating cavity and is close to the liquid nitrogen adsorption cotton, and the freezing storage box is used for storing biological samples;
the temperature sensor is arranged in the accommodating cavity;
an operation display unit on which a user can input a set temperature;
the analysis control unit, the control valve with temperature sensor all with analysis control unit electricity is connected, temperature sensor uploads the temperature information that detects to analysis control unit, analysis control unit will receive temperature information uploads to operation display unit, operation display unit will the temperature information shows, operation display unit will set for the temperature upload to analysis control unit, analysis control unit according to the temperature information with set for the temperature controls opening or closing of control valve.
2. The cryogenic transfer car (buggy) for biological specimens according to claim 1,
the vehicle body comprises a vehicle body and a heat insulator arranged on the upper part of the vehicle body, the heat insulator comprises a heat insulation bottom wall and a heat insulation side wall connected with the heat insulation bottom wall, and the heat insulator encloses the accommodating cavity;
the liquid nitrogen container is arranged inside the vehicle body, the liquid nitrogen adsorption cotton is arranged at the bottom of the accommodating cavity, and the freezing storage box is arranged at the upper part of the liquid nitrogen adsorption cotton.
3. The cryogenic transfer car (buggy) for biological specimens according to claim 2,
the bottom that holds the chamber is equipped with and is used for placing the liquid nitrogen adsorbs the cotton liquid nitrogen chamber.
4. The biological specimen cryogenic transfer car (buggy) of claim 3, further comprising:
and the freezing frame is close to the liquid nitrogen cavity, and the freezing box is arranged in the freezing frame.
5. The cryogenic transfer car (buggy) for biological specimens according to claim 3,
the heat insulation body is a vacuum-pumping heat insulation layer.
6. The cryogenic transfer car (buggy) for biological specimens according to claim 4,
and a cold guide plate is arranged on one side of the heat-preservation side wall facing the accommodating cavity, and the lower end of the cold guide plate is tightly attached to the upper surface of the liquid nitrogen cavity.
7. The cryogenic transfer car of biological specimens according to claim 6,
the freezing storage box comprises a containing cavity, a freezing storage rack and a bracket body, wherein the containing cavity is internally provided with an operating bracket, the operating bracket comprises a bracket body and flanges arranged on two sides of the bracket body, and the bracket body is used for placing the freezing storage box.
8. The cryogenic transfer car (buggy) for biological specimens according to claim 7,
the flanging is movably lapped with the upper end of the cold guide plate.
9. The biological specimen cryogenic transfer vehicle of any one of claims 3 to 8,
the temperature sensor is arranged above the liquid nitrogen cavity.
10. The cryogenic transfer car of biological specimens according to claim 9,
the upper part of the containing cavity is provided with a door body which can be opened and closed.
CN201921735759.9U 2019-10-16 2019-10-16 Biological sample low temperature transfer car (buggy) Active CN211042530U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201921735759.9U CN211042530U (en) 2019-10-16 2019-10-16 Biological sample low temperature transfer car (buggy)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201921735759.9U CN211042530U (en) 2019-10-16 2019-10-16 Biological sample low temperature transfer car (buggy)

Publications (1)

Publication Number Publication Date
CN211042530U true CN211042530U (en) 2020-07-17

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ID=71538593

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Application Number Title Priority Date Filing Date
CN201921735759.9U Active CN211042530U (en) 2019-10-16 2019-10-16 Biological sample low temperature transfer car (buggy)

Country Status (1)

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CN (1) CN211042530U (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113281192A (en) * 2021-06-18 2021-08-20 中国船舶重工集团公司第七二五研究所 Cold-hot alternating fatigue test method under constant stress

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113281192A (en) * 2021-06-18 2021-08-20 中国船舶重工集团公司第七二五研究所 Cold-hot alternating fatigue test method under constant stress

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