CN211026175U - Wet granulation device - Google Patents
Wet granulation device Download PDFInfo
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- CN211026175U CN211026175U CN201921952390.7U CN201921952390U CN211026175U CN 211026175 U CN211026175 U CN 211026175U CN 201921952390 U CN201921952390 U CN 201921952390U CN 211026175 U CN211026175 U CN 211026175U
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Abstract
The utility model discloses a wet granulation device can fully atomize the binder, and the atomizing area is big, and atomization effect is good. The wet granulation device comprises a granulator container and a granulator pot cover, wherein a stirring assembly is arranged at the bottom of the granulator container, a cutting assembly is arranged on one side of the granulator container along the radial direction, a two-flow atomizer is arranged on the granulator pot cover and provided with a liquid nozzle and a gas nozzle, the two-flow atomizer is respectively connected with a liquid path assembly and a gas path assembly, the liquid path assembly is communicated with the liquid nozzle, the gas path assembly is communicated with the gas nozzle, the gas nozzle is annular and surrounds the liquid nozzle, the liquid path assembly is used for inputting a bonding agent, and the gas path assembly is used for inputting gas for atomizing the bonding agent.
Description
Technical Field
The utility model relates to a pharmaceutical equipment technical field especially relates to a wet granulation device.
Background
At present, a wet granulating machine needs to fully mix powdered medicine and adhesive in a container at a high speed by a bottom mixing paddle (stirring component) to form a wet soft material, and then the wet soft material is cut into uniform particles by a side high-speed crushing paddle (cutting component), so that the aim of granulating is fulfilled.
However, when the existing wet granulation device is used for treating the adhesive, the adopted modes generally comprise ladling, funnel gravity inflow, simple nozzles and the like, the adhesive is easy to accumulate at one position, and the adhesive cannot be effectively dispersed or atomized, so that the medicine granulation is not uniform, the medicine particle content is unstable, the layering is easy to crack, the medicine particle quality is reduced, and the medicine use effect is seriously even influenced.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to overcome prior art not enough, provide a wet granulation device, can fully atomize the binder, the atomizing area is big, and atomization effect is good.
The purpose of the utility model is realized like this:
the wet granulation device comprises a granulator container and a granulator pot cover, wherein a stirring assembly is arranged at the bottom of the granulator container, a cutting assembly is arranged on one side of the granulator container along the radial direction, a two-flow atomizer is arranged on the granulator pot cover and provided with a liquid nozzle and a gas nozzle, the two-flow atomizer is respectively connected with a liquid path assembly and a gas path assembly, the liquid path assembly is communicated with the liquid nozzle, the gas path assembly is communicated with the gas nozzle, the gas nozzle is annular and surrounds the liquid nozzle, the liquid path assembly is used for inputting a bonding agent, and the gas path assembly is used for inputting gas for atomizing the bonding agent.
Preferably, the two-flow atomizer is located in the incoming direction of the cutting assembly.
Preferably, the two-flow atomizer is located in the 90-180 degree area of the feeding direction of the cutting assembly by taking the center of the stirring assembly as an origin.
Preferably, the two-flow atomizer still has liquid barrel, gas barrel, distributor, valve body, the liquid barrel is located the gas barrel, makes and forms the air current passageway between liquid barrel, the gas barrel, the valve body has liquid flow path, air current channel, liquid flow path communicates with the export of liquid barrel, liquid nozzle respectively, air current channel communicates with the export of gas barrel, gas nozzle respectively, the distributor includes straight section of thick bamboo portion, side section of thick bamboo portion, the one end opening of straight section of thick bamboo portion, the other end is sealed, and the open end of straight section of thick bamboo portion cup joints and communicates with the import of gas barrel, and the sealed end of straight section of thick bamboo portion is fixed with the liquid barrel is sealed, the access connection of liquid barrel the liquid way subassembly, the one end and the straight section of thick bamboo portion intercommunication of side section of thick bamboo portion, the.
Preferably, the valve body is respectively provided with a threaded connection port of the liquid barrel, a threaded connection port of the gas barrel, a threaded connection port of the liquid nozzle, a threaded connection port of the gas nozzle, a threaded connection port of the liquid barrel, a threaded connection port of the gas nozzle and a threaded connection port of the gas barrel, a threaded connection port of the liquid nozzle and a threaded connection port of the gas nozzle are communicated with a gas flow passage of the valve body, and the liquid barrel, the gas barrel, the liquid nozzle, the gas nozzle and the valve body are respectively sealed;
the opening end of the straight cylinder part is in threaded fit with the gas barrel and is sealed through the sealing ring, the sealing end of the straight cylinder part is in threaded fit/clearance fit with the liquid barrel, the liquid barrel is provided with the locking nut for locking the straight cylinder part and the liquid barrel, and the sealing end of the locking nut and the straight cylinder part is sealed through the sealing ring.
Preferably, the two-flow atomizer is installed on the cover of the granulator pot through a locking mechanism, the locking mechanism comprises a locking nut, a locking sleeve and a locking base, the locking nut, the locking sleeve and the locking base are respectively sleeved on the gas barrel, the locking sleeve is made of an elastic material, the upper end and the lower end of the locking sleeve are both conical, the upper end of the locking nut is in a conical hole shape and is matched with the locking sleeve, the inner side of the upper end of the locking base is in a conical hole shape and is matched with the lower end of the locking sleeve, the outer side of the upper end of the locking base is in threaded fit with the lower end of the locking nut, and the lower end of the locking base is connected with a connector arranged on the cover of the granulator pot.
Preferably, the gas gun barrel is provided with scale marks for observing and recording the upper and lower positions of the two-flow atomizer;
the material of lock sleeve is polytetrafluoroethylene, be equipped with food level silicon rubber sealing washer between locking base and the gas barrel.
Preferably, the liquid nozzle is internally provided with a liquid turbulence ring for primary atomization of the adhesive, and the gas nozzle is internally provided with a gas turbulence ring for secondary atomization of the adhesive.
Preferably, the axes of the gas nozzle and the liquid nozzle of the two-flow atomizer form an included angle of 22.5 degrees with the axes of the gas barrel and the liquid barrel.
Preferably, the gas path assembly comprises a gas pipe and a gas quick coupler, and the gas quick coupler is connected with the side cylinder part; the liquid path component comprises a liquid pipe and a locking type liquid pipe joint, and the locking type liquid pipe joint is connected with an inlet of the liquid gun barrel through a fast-assembling clamp.
Since the technical scheme is used, the utility model discloses following beneficial effect has:
the technical problems that when a wet granulation device in the prior art atomizes the adhesive, the adhesive is easy to accumulate, the atomization area is small, the atomization effect is poor, so that the drug granulation is not uniform, the drug particle content is unstable, the layering is easy to crack, and the quality and the effect of the drug particles are influenced are solved.
The adhesive can be sprayed along the tangential direction of material operation during wet granulation. When the wet granulation device atomizes the adhesive, the injection route of the adhesive does not influence the movement track of the material, the adhesive is not easy to accumulate at one position, the atomization area is increased, the atomization effect is improved, the combination probability of the material and the adhesive in the movement period is equivalent, the uniform granulation of the medicine is ensured, the medicine particles are not easy to crack in a layering way, the quality of the medicine particles is improved, the locking mechanism and the gun barrel scale enable the granulation device to repeatedly and stably realize a good granulation process, the process stability and the reproducibility of the wet granulation are greatly improved, and the granulation effect is greatly optimized.
Drawings
Fig. 1 is a schematic structural diagram of the present invention;
FIG. 2 is a schematic structural view of a two-flow atomizer;
FIG. 3 is a schematic structural view of the locking mechanism;
FIG. 4 is a schematic view of an air path assembly and a fluid path assembly;
fig. 5 is a schematic plan view of the present invention;
FIG. 6 is a schematic cross-sectional view of the connection of the valve body, gas nozzle, liquid nozzle;
FIG. 7 is a graph of the dispersion effect of a two-flow atomizer under the pressure of a binder liquid;
fig. 8 is a diagram showing the atomization effect of the two-flow atomizer under the dual action of gas and liquid.
Reference numerals
In the attached drawing, 1-locking mechanism, 2-two-flow atomizer, 3-granulator pot cover, 4-gas nozzle, 5-liquid nozzle, 6-gas path component, 7-liquid path component, 8-gas nozzle, 9-liquid nozzle, 11-valve body, 12-liquid path sealing ring, 13-liquid gun barrel, 14-locking nut, 15-gas gun barrel, 16-gas pipe sealing ring, 17-distributor, 18-locking base, 19-locking nut, 20-scale mark, 21-polytetrafluoroethylene locking sleeve, 22-sealing ring, 23-polyurethane transparent gas pipe, 24-gas joint, 25-liquid pipe, 26-locking stainless steel pipe joint, 27-quick-assembly clamp, 28-cutting knife (cutting component), etc, 29-two-flow atomizer mounting area, 33-liquid turbulence ring, 34-gas turbulence ring.
Detailed Description
Referring to fig. 1 to 8, in order to provide an embodiment of a wet granulation apparatus of the present invention, the wet granulation apparatus includes a locking mechanism 1, a gas circuit component 6, a liquid circuit component 7, and a two-flow atomizer 2; the locking mechanism 1 comprises a locking base 18, a locking nut 19 and a polytetrafluoroethylene locking sleeve 21; the gas circuit component 6 comprises a gas pipe 23 and a gas quick connector 24; the liquid path component 7 comprises a liquid pipe 25 and a locking type stainless steel liquid pipe joint 26; the two-flow atomizer 2 comprises a distributor 17, a gas gun tube 15, a liquid gun tube 13, a valve body 11, a gas nozzle 8 and a liquid nozzle 9; the two-flow atomizer 2 is installed on a pot cover 3 of a wet granulating machine, scale marks 20 are arranged on a gas gun tube 15 of the two-flow atomizer 2, the two-flow atomizer 2 can move up and down through a locking mechanism 1 on the pot cover 3, the gas gun tube 15 is arranged outside the two-flow atomizer 2, a gas turbulence ring 34 is arranged in a gas nozzle 8, a liquid gun tube 13 is arranged inside the two-flow atomizer 2, a liquid turbulence ring 33 is arranged in a liquid nozzle 9, the axial lines of the gas nozzle 8, the liquid nozzle 9 and a valve body 11 of the two-flow atomizer 2 form an included angle of 22.5 degrees with the axial lines of the gas gun tube 15 and the liquid gun tube 13, and an adhesive can be sprayed in the tangential direction of material operation during wet granulation. The gas nozzle is the annular, and surrounds liquid nozzle, and after forming the contained angle, liquid nozzle has been enclosed by gas nozzle, by gaseous dispersion when liquid flows, can not take place the condition of liquid adhesion nozzle, and in addition, liquid is difficult for taking place the flow field disorder after flowing from liquid nozzle, and then effectively prevents liquid adhesion on the spray gun head (if there is the adhesion phenomenon to take place to cause the spraying failure easily).
In the present embodiment, the two-flow atomizer 2 is fixedly connected with the pelletizer pan cover 3; the two-flow atomizer 2 is connected with the locking mechanism 1, the two-flow atomizer 2 is positioned at a specific position on the pot cover 3 of the wet granulator, the position is positioned in the area of 90-180 degrees in front of the cutting knife, a food-grade silicon rubber sealing ring 22 is arranged between the two-flow atomizer 2 and the locking mechanism 1, a scale mark 20 is arranged on a gas gun barrel 15 of the two-flow atomizer 2, and an included angle of 22.5 is formed between the axial lead of a valve body 11, a gas nozzle 8 and a liquid nozzle 9 of the two-flow atomizer 2 and the axial lead of the outer pipe of the atomizer; a liquid turbulence ring 33 is arranged in a liquid nozzle 9 of the two-flow atomizer 2, liquid passes through the turbulence ring and forms a dispersion effect under the action of the self pressure of the liquid, so that the first atomization and dispersion of the liquid into large particles are achieved, the larger the liquid pressure is, the smaller the dispersed particles are, the base materials of the wet granulator are dry fine powder at the early stage of granulation, and the dust is easy to raise, the liquid nozzle 9 of the two-flow atomizer 2 is adopted to directly spray the liquid, so that the materials can be humidified, and the dust of the fine powder cannot be raised; the outside of liquid nozzle 9 is gas nozzle 8, and gas nozzle 8 is inside to be equipped with gaseous turbulent ring 34, and gaseous spraying can form the secondary atomizing to liquid at last for foretell dispersion large granule diminishes, is favorable to going on smoothly of granulation more, and the material has become moist soft material through dry farine in this stage, even have gaseous blowing-in pot internal portion, can not cause the emergence of raise dust phenomenon yet, thereby can be good completion granulation process.
The adhesive can be sprayed along the tangential direction of material operation during wet granulation. When the wet granulation device atomizes the adhesive, the injection route of the adhesive does not influence the movement track of the material, the adhesive is not easy to accumulate at one position, the atomization area is increased, the atomization effect is improved, the combination probability of the material and the adhesive in the movement period is equivalent, the uniform granulation of the medicine is ensured, the medicine particles are not easy to crack in a layering way, the quality of the medicine particles is improved, the locking mechanism 1 and the gun barrel scale enable the granulation device to repeatedly and stably realize a good granulation process, the process stability and the reproducibility of the wet granulation are greatly improved, and the granulation effect is greatly optimized.
The granulator pot cover is all run through perpendicularly to gas barrel 15 and liquid barrel 13, gas nozzle 8 and liquid nozzle 9 all pass through threaded connection on valve body 11, gas barrel 15, liquid barrel 13 and distributor 17 are connected with valve body 11 through screw thread and nut, gas barrel 15 cover is in the outside of liquid barrel 13, and the axial lead of gas barrel 15 and liquid barrel 13 coincides each other, gas nozzle 8, liquid nozzle 9 are connected with valve body 11 and are accomplished the back, and the export of liquid nozzle 9 is higher than the export of gas nozzle 8 there is the taper hole locking base's upper end, and the polytetrafluoroethylene tensioning cover cooperation of via hole in the middle of this taper hole and the two-end conic section, 19 one end of locking nut has the taper hole, the taper hole cooperates with the other one-end conic section of polytetrafluoroethylene tensioning cover, reaches the purpose of locking rifle pole.
In the embodiment, the locking mechanism 1 comprises a locking base, a locking nut 19 and a locking sleeve, wherein the locking base and the locking nut 19 are both made of 316L materials, the locking sleeve is made of Polytetrafluoroethylene (PTFE) materials, the gas circuit component 6 is made of a stainless steel quick-mounting joint and a polyurethane transparent gas pipe 23, the liquid circuit component 7 is made of a stainless steel locking joint, silicon rubber or polyurethane liquid pipe, the two-flow atomizer 2 comprises a distributor 17, a gas gun pipe 15, a liquid gun pipe 13, a valve body 11, a gas nozzle 8 and a liquid nozzle 9, except that a sealing ring 22 is made of food-grade silicon rubber materials, the rest is made of 316L stainless steel materials, the two-flow atomizer 2 is connected with the locking mechanism 1, a scale mark 20 is arranged on an outer pipe of the two-flow atomizer, the locking base and the locking nut move in opposite directions to deform and lock the locking sleeve, and the locking sleeve moves in opposite directions to be unlocked, and the lower end of the locking base is connected with a pot cover on the granulator through a locking type liquid pipe joint and an atomizing.
In the embodiment of the present invention, when the locking mechanism 1 is released, the two-flow type atomizer 2 can move up and down and also can rotate 360 degrees along the axial line of the gas barrel 15, so that the spraying area of the whole atomizer can be moved in a large range, and the gas barrel 15 of the two-flow type atomizer 2 is provided with the scale marks 20, which can record the up-and-down position of the two-flow type atomizer 2, and can be repeatedly positioned for a plurality of times, thereby ensuring the stability.
The liquid nozzle 9 is internally provided with a liquid turbulence ring 33, and the gas nozzle is internally provided with a gas turbulence ring 34. After the liquid passes through the liquid turbulence ring 33, a dispersion effect is formed under the action of the self pressure of the liquid, so that the first atomization and dispersion of the liquid into large particles are achieved, the larger the liquid pressure is, the smaller the dispersed particles are, the bottom materials of the wet granulator are dry fine powder in the early stage of granulation, and the dust is easy to raise, the liquid nozzle 9 of the two-flow atomizer 2 is adopted to directly spray the liquid, the material humidification is facilitated, and the dust raising of the fine powder is avoided; the outside of two flow liquid nozzle 9 is gas nozzle 8, and gas nozzle 8 is inside to be equipped with gaseous turbulent ring 34, and gas is through this spouting can form the secondary atomizing to liquid at last for foretell dispersion large granule diminishes, is favorable to going on smoothly of granulation more, and the material has become moist soft material through dry farine in this stage, even have gas to blow in the pot body inside, can not cause the emergence of raise dust phenomenon yet, thereby can be good the completion granulation process.
In addition, the two-flow atomizer 2 and the granulator pot cover 3 have specific installation positions, under the condition of overlooking from top to bottom, materials in the wet granulation machine run anticlockwise, the front 90-180-degree area of the arc position of the cutting knife 28 is an installation area of the two-flow atomizer 2, the two-flow atomizer 2 is installed in the area, the combination area of liquid and the materials can be located in front of the cutting knife 28, and after the liquid and the materials are combined, the cutting knife 28 cuts at a high speed, so that uniform granulation is facilitated.
The kinetic energy of the two-flow atomizer without air atomization (only adhesive is introduced) comes from a peristaltic pump driven by a servo motor, the rotating speed of the servo motor is controlled through a program, the servo motor works at a high rotating speed to form high-flow-rate adhesive liquid, the high-flow-rate adhesive impacts a turbulent ring in a liquid nozzle to realize atomization, and the program can set the running time and the running rotating speed; the atomizing (simultaneously introducing the adhesive and the atomizing gas) is realized by introducing the atomizing gas on the basis of no-gas atomization, the opening and closing of the atomizing gas are controlled by the opening and closing of an electromagnetic valve, the pressure of the atomizing gas is controlled by a pressure regulating valve, the electromagnetic valve and the pressure regulating valve are respectively controlled by a program, and then the liquid particles are atomized to be finer by externally introducing gas flow.
Finally, it is noted that the above-mentioned preferred embodiments illustrate rather than limit the invention, and that, although the invention has been described in detail with reference to the above-mentioned preferred embodiments, it will be understood by those skilled in the art that various changes in form and details may be made therein without departing from the scope of the invention as defined by the appended claims.
Claims (10)
1. The utility model provides a wet granulation device, includes granulator container, granulator pot cover, the bottom of granulator container sets up the stirring subassembly, one side of granulator container is along radially being equipped with cutting assembly, its characterized in that: the granulator pot cover is provided with a two-flow atomizer, the two-flow atomizer is provided with a liquid nozzle and a gas nozzle, the two-flow atomizer is respectively connected with a liquid path component and a gas path component, the liquid path component is communicated with the liquid nozzle, the gas path component is communicated with the gas nozzle, the gas nozzle is annular and surrounds the liquid nozzle, the liquid path component is used for inputting adhesive, and the gas path component is used for inputting gas for atomizing the adhesive.
2. A wet granulation apparatus as defined in claim 1, wherein: the two-flow atomizer is located in the feeding direction of the cutting assembly.
3. A wet granulation apparatus as defined in claim 2, wherein: the center of the stirring assembly is used as an original point, and the two-flow atomizer is positioned in a 90-180-degree area of the incoming material direction of the cutting assembly.
4. A wet granulation apparatus as defined in claim 1, wherein: the two-flow atomizer still has liquid barrel, gas barrel, distributor, valve body, the liquid barrel is located gas barrel, makes to form airflow channel between liquid barrel, the gas barrel, the valve body has liquid flow path, air current channel, liquid flow path communicates with export, the liquid nozzle of liquid barrel respectively, air current channel communicates with export, the gas nozzle of gas barrel respectively, the distributor includes straight section of thick bamboo portion, side section of thick bamboo portion, the one end opening of straight section of thick bamboo portion, the other end seals, and the open end of straight section of thick bamboo portion cup joints and communicates with the import of gas barrel, and the end of sealing of straight section of thick bamboo portion is fixed with the liquid barrel is sealed, the access connection of liquid barrel the liquid way subassembly, the one end and the straight section of thick bamboo portion intercommunication of side section of thick bamboo portion, the other end.
5. A wet granulation apparatus as claimed in claim 4, wherein: the valve body is respectively provided with a liquid gun barrel, a gas gun barrel, a liquid nozzle and a threaded connector of the gas nozzle, the threaded connectors of the liquid gun barrel and the liquid nozzle are communicated with a liquid flow channel of the valve body, the threaded connectors of the gas gun barrel and the gas nozzle are communicated with an air flow channel of the valve body, and the liquid gun barrel, the gas gun barrel, the liquid nozzle, the gas nozzle and the valve body are respectively sealed through sealing rings;
the opening end of the straight cylinder part is in threaded fit with the gas barrel and is sealed through the sealing ring, the sealing end of the straight cylinder part is in threaded fit/clearance fit with the liquid barrel, the liquid barrel is provided with the locking nut for locking the straight cylinder part and the liquid barrel, and the sealing end of the locking nut and the straight cylinder part is sealed through the sealing ring.
6. A wet granulation apparatus as claimed in claim 4, wherein: the two-flow atomizer is installed on the cover of the granulator pot through a locking mechanism, the locking mechanism comprises a locking nut, a locking sleeve and a locking base, the locking nut, the locking sleeve and the locking base are respectively sleeved on a gas gun barrel, the locking sleeve is made of elastic materials, the upper end and the lower end of the locking sleeve are both conical holes, the upper end of the locking nut is in a conical hole shape and matched with the locking sleeve, the inner side of the upper end of the locking base is in a conical hole shape and matched with the lower end of the locking sleeve, the outer side of the upper end of the locking base is in threaded fit with the lower end of the locking nut, and the lower end of the locking base is connected with a connector arranged on the granulator pot cover.
7. A wet granulation apparatus as claimed in claim 6, wherein: the gas gun tube is provided with scale lines for observing and recording the upper and lower positions of the two-flow atomizer;
the material of lock sleeve is polytetrafluoroethylene, be equipped with food level silicon rubber sealing washer between locking base and the gas barrel.
8. A wet granulation apparatus as claimed in claim 4, wherein: the liquid nozzle is internally provided with a liquid turbulence ring for primary atomization of the adhesive, and the gas nozzle is internally provided with a gas turbulence ring for secondary atomization of the adhesive.
9. A wet granulation apparatus as claimed in claim 4, wherein: the axes of the gas nozzle and the liquid nozzle of the two-flow atomizer form an included angle of 22.5 degrees with the axes of the gas gun tube and the liquid gun tube.
10. A wet granulation apparatus as claimed in claim 4, wherein: the gas path assembly comprises a gas pipe and a gas quick coupler, and the gas quick coupler is connected with the side barrel part; the liquid path component comprises a liquid pipe and a locking type liquid pipe joint, and the locking type liquid pipe joint is connected with an inlet of the liquid gun barrel through a fast-assembling clamp.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201921952390.7U CN211026175U (en) | 2019-11-13 | 2019-11-13 | Wet granulation device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201921952390.7U CN211026175U (en) | 2019-11-13 | 2019-11-13 | Wet granulation device |
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| Publication Number | Publication Date |
|---|---|
| CN211026175U true CN211026175U (en) | 2020-07-17 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201921952390.7U Active CN211026175U (en) | 2019-11-13 | 2019-11-13 | Wet granulation device |
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| CN (1) | CN211026175U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110694549A (en) * | 2019-11-13 | 2020-01-17 | 重庆力耘喷嘴有限公司 | Wet granulation device |
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2019
- 2019-11-13 CN CN201921952390.7U patent/CN211026175U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110694549A (en) * | 2019-11-13 | 2020-01-17 | 重庆力耘喷嘴有限公司 | Wet granulation device |
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