CN210990958U

CN210990958U - Layered degradable polymer stent

Info

Publication number: CN210990958U
Application number: CN201921341098.1U
Authority: CN
Inventors: 孙鹏; 黄秀珍; 孟秀
Original assignee: Shanghai Qimu Medical Equipment Co ltd
Current assignee: Shanghai Qimu Medical Equipment Co ltd
Priority date: 2019-08-16
Filing date: 2019-08-16
Publication date: 2020-07-14
Anticipated expiration: 2029-08-16

Abstract

The utility model relates to the technical field of medical equipment, concretely relates to layering degradable polymer support, the unstable defect of degradation that the technical problem that aims at solving lies in overcoming among the prior art mainly can be realized through following technical scheme: the bracket main body is of a tubular structure and is formed by weaving fiber yarns, and the fiber yarns form a first circular ring and a reinforcing ring; the first circular rings are arranged in plurality to form a support main body and are longitudinally arranged along the support main body; the reinforcing ring is connected different first rings simultaneously along support main part longitudinal arrangement, adopts the support main part that first ring and reinforcing ring constitute, through the interconnect of linking arm and circular arc section, after the support main part expansion, can form stable bearing structure to the radial holding power of reinforcing support adopts different biodegradable materials can degrade in proper order in vivo, has avoided the support piece to cause harmful effects to the human body at the in-process of support endothelialization, can accelerate endothelialization restoration speed.

Description

Layered degradable polymer stent

Technical Field

The utility model relates to the technical field of medical equipment, concretely relates to layering degradable polymer support.

Background

Clinically, the basic requirements for the implantation of instruments in the human body's lumen include: after the apparatus is implanted into the organ of human body, it can not only provide enough mechanical support force for the implanted organ, but also slowly, continuously and uniformly release the medicine into the wall of the inner tube cavity of the organism, so as to effectively control the foreign body reaction caused by implanting the prosthesis.

The stent may be made from a variety of materials, including metallic and polymeric materials. Among the polymer scaffolds, biodegradable polymer scaffolds have many advantages: firstly, after the degradable stent is implanted into the lumen, the degradable stent can be automatically absorbed by the organism after the dilation and the support of the narrow lumen are finished, so that late thrombosis and restenosis sequelae caused by the long-term retention of the non-degradable stent in the body are avoided; and the degradable polymer body can be filled with drugs for inhibiting the restenosis of the blood vessel, and the drugs are slowly released along with the degradation of the stent after the stent is implanted, so that the restenosis of the blood vessel can be effectively controlled for a long time. In the conventional metal drug stent, the drug can be sprayed only on the surface of the metal stent and released within 28 days after the stent is implanted.

The existing biodegradable polymer scaffold is made of an integrally formed biodegradable material in an extruded tube form or a monofilament fiber weaving form. After the biodegradable stent prepared by the method is implanted into a human body, due to the irregular degradability of materials in the degradation process, irregular fragment breakage can be caused in the middle and last stages of degradation of the stent, so that tiny fragments degraded by the stent can enter the human body, and adverse side reactions can be caused at the pathological change part of the implanted stent. For example: intravascular stents can cause platelet aggregation leading to thrombus formation within the stent; tiny fragments in the trachea can cause a relatively violent foreign body reaction in the trachea.

SUMMERY OF THE UTILITY MODEL

Therefore, the to-be-solved technical problem of the utility model lies in overcoming the unstable defect of degradation among the prior art to a hierarchical degradable polymer support is provided.

The above technical purpose of the present invention can be achieved by the following technical solutions:

a layered degradable polymer scaffold comprising:

the stent comprises a stent main body which is of a tubular structure and is formed by weaving fiber yarns, wherein the fiber yarns form a first circular ring and a reinforcing ring;

a plurality of first rings which form the bracket main body and are arranged along the longitudinal direction of the bracket main body;

and the reinforcing rings are longitudinally arranged along the stent main body and are simultaneously connected with different first circular rings.

Furthermore, the first circular rings are fixed through S-shaped connecting arms, and the first circular rings and the connecting arms are integrally arranged.

Furthermore, the reinforcing ring is arranged in a rhombic shape, the reinforcing ring is connected with the first circular ring through an arc section, and the arc sections are symmetrically arranged in a plurality.

Further, the reinforcing ring and the first circular ring are made of the same material, and both the reinforcing ring and the first circular ring are of a multilayer structure.

Furthermore, the fiber yarns are made of multiple layers of biodegradable materials with different rates, and the degradation speed is increased from inside to outside in sequence.

Further, the fiber filament material comprises a degradable metal-based material.

Furthermore, a biological identification point is also arranged on the bracket main body.

The utility model discloses technical scheme has following advantage:

1. the utility model provides a pair of layering degradable polymer support adopts the support main part that first ring and reinforcing ring constitute, through the interconnect of linking arm and circular arc section, after the support main part expansion, can form stable bearing structure to strengthen the radial holding power of support.

2. The utility model provides a pair of layered degradable polymer support, adopt the biodegradable material layer that different biodegradable materials made, after layered degradable polymer support implants the human body, each layer biodegradable material is by outer to interior degradation in proper order, the biodegradable polymer material layer that does not degrade has played the effect of adhering to and supporting the biodegradable polymer material layer that begins to degrade, the in-process of endothelialization in the support has been avoided the support piece to cause harmful effects to the human body, can accelerate endothelialization restoration speed.

3. The utility model provides a pair of layered degradable polymer support, support main part itself is required medicine promptly to can avoid or reduce oral medicine and use during implanting, can alleviate mucosa inflammation and edema, promote mucosa healing, reduce the scar and form, eliminate the postoperative adhesion, this support main part adopts degradable material to make, and a period can automatic degradation after the art, need not to take out.

Drawings

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the embodiments or the technical solutions in the prior art will be briefly described below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without creative efforts.

Fig. 1 is a schematic plan view of a layered degradable polymer scaffold according to an embodiment of the present invention;

description of reference numerals:

1. a stent body; 11. fiber yarn; 12. a biometric identification point; 2. a first circular ring; 21. a connecting arm; 3. a reinforcing ring; 31. a circular arc segment.

Detailed Description

The technical solution of the present invention will be described clearly and completely with reference to the accompanying drawings, and obviously, the described embodiments are some, but not all embodiments of the present invention. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.

A layered degradable polymer stent is shown in figure 1, a stent main body 1 which is unfolded in a plane is formed by weaving fiber yarns 11, the fiber yarns 11 form first circular rings 2 and reinforcing rings 3, the first circular rings 2 are longitudinally arranged along the stent main body 1, the reinforcing rings 3 are longitudinally arranged along the stent main body 1 and are simultaneously connected with two different rows of the first circular rings 2, and the reinforcing rings 3 are connected and fixed through the fiber yarns 11; the first circular rings 2 are vertically arranged and fixed through S-shaped connecting arms 21, and the first circular rings 2 and the connecting arms 21 are integrally arranged; reinforcing ring 3 is the rhombus setting, is connected through circular arc section 31 between reinforcing ring 3 and first ring 2, is provided with two pairs of circular arc sections 31 on every reinforcing ring 3 respectively with the first ring 2 fixed connection of difference, adopts the support main part 1 that first ring 2 and reinforcing ring 3 constitute, through linking arm 21 and the interconnect of circular arc section 31, after support main part 1 expansion, can form stable bearing structure to strengthen the radial holding power of support.

As shown in fig. 1, the reinforcing ring 3 is made of the same material as the first ring 2, the reinforcing ring 3 and the first ring 2 are both of a multilayer structure, the fiber 11 is made of a multilayer biodegradable material with different rates, the biodegradable polymer material includes polylactic acid P L a, L-P L a, polyglycolic acid/polylactic acid copolymer PG L a, polycaprolactone PC L, polyhydroxybutyrate valerate PHBV, polyacetylglutamic acid PAGA, polyorthoester POE, polyethylene oxide/polybutylene oxide copolymer PEO/PBTP, polylactide-co-caprolactone copolymer P L C or polycyclohexanone PDO, the degradation rate is sequentially increased from inside to outside, and the fiber 11 material includes a degradable metal-based material.

As shown in fig. 1, the stent body 1 is further provided with a biological recognition site 12 attached to the surface of the stent body 1 or embedded therein, so as to detect or recognize the position of the stent body 1 after implantation for easy confirmation and adjustment.

The manufacturing method of the layered degradable polymer scaffold comprises the following steps: the preparation method comprises the steps of firstly preparing fiber yarns 11 from biodegradable materials with different degradation speeds, then weaving the fiber yarns 11 into first circular rings 2 and reinforcing rings 3, and finally forming a support main body 1 from the first circular rings 2 and the reinforcing rings 3.

It should be understood that the above examples are only for clarity of illustration and are not intended to limit the embodiments. Other variations and modifications will be apparent to persons skilled in the art in light of the above description. And are neither required nor exhaustive of all embodiments. And obvious variations or modifications can be made without departing from the scope of the invention.

Claims

1. A layered, degradable polymer scaffold, comprising:

the stent comprises a stent main body (1) which is of a tubular structure, wherein the stent main body (1) is formed by weaving fiber yarns (11), and the fiber yarns (11) form a first circular ring (2) and a reinforcing ring (3);

a plurality of first circular rings (2) which form the bracket main body (1) and are longitudinally arranged along the bracket main body (1);

the reinforcing rings (3) are longitudinally arranged along the stent main body (1) and are simultaneously connected with different first circular rings (2).

2. The layered degradable polymer scaffold according to claim 1 characterized in that said first rings (2) are fixed by S-shaped linking arms (21), said first rings (2) are integrated with said linking arms (21).

3. The layered degradable polymer stent of claim 2, wherein the reinforcing ring (3) is arranged in a diamond shape, the reinforcing ring (3) is connected with the first circular ring (2) through a plurality of circular arc sections (31), and the plurality of circular arc sections (31) are symmetrically arranged.

4. A layered degradable polymer scaffold according to claim 3 characterized in that said reinforcement ring (3) is of the same material as said first circular ring (2) and both said reinforcement ring (3) and said first circular ring (2) are of multilayer structure.

5. The layered degradable polymer stent as claimed in claim 4, wherein the fiber filaments (11) are made of multiple layers of biodegradable materials with different rates, and the degradation speed increases from inside to outside.

6. A layered degradable polymer scaffold according to claim 5 characterized in that said fiber filament (11) material comprises degradable metal based material.

7. A layered degradable polymer stent according to claim 6 characterized in that said stent body (1) is further provided with biological recognition points (12).