CN210963070U

CN210963070U - Equipment for preparing six-ingredient rehmannia paste by extracting and separating paeonol from compound traditional Chinese medicine water

Info

Publication number: CN210963070U
Application number: CN201921370673.0U
Authority: CN
Inventors: 刘旭海; 王谷洪; 赵海金; 季巧遇; 周友华; 李诒光; 朱明辉; 吴样明
Original assignee: Jiangzhong Pharmaceutical Co Ltd
Current assignee: Jiangzhong Pharmaceutical Co Ltd
Priority date: 2019-08-22
Filing date: 2019-08-22
Publication date: 2020-07-10
Anticipated expiration: 2029-08-22

Abstract

The utility model discloses a traditional chinese medicine compound water extracts equipment of preparing six ingredients rehmannia root paste of separation paeonol, equipment comprises extraction system, concentration system and nanofiltration membrane filtration system, utilizes the utility model discloses equipment can realize continuous production, continuous concentration, continuous ejection of compact, has optimized and has needed to adopt the steam distillation method to extract separation paeonol cooling crystallization earlier among the traditional preparation method, later with cortex moutan dregs of a decoction and other medicinal materials decocte the concentration go out the extract, again with the paeonol crystal of separating and carry out the production technology that mixes with the extract; the preparation method using the equipment for production only needs one-time concentration, greatly shortens the production time, improves the production efficiency, can realize industrial continuous production, retains the active ingredients of paeonol of the moutan bark extract by using the equipment for production, has high paeonol transfer rate, and has important significance for fully utilizing medicinal material resources.

Description

Equipment for preparing six-ingredient rehmannia paste by extracting and separating paeonol from compound traditional Chinese medicine water

Technical Field

The utility model relates to the field of traditional Chinese medicine extraction devices, in particular to equipment applied to a process method for collecting paeonol as an effective component in traditional Chinese medicine compound decoction containing cortex moutan medicinal materials.

Background

Paeonol is an effective component extracted from dried root bark of Paeonia suffruticosa Andr. Melting point 49-51 deg.C, special smell, slightly spicy taste, easy to dissolve in ethanol and methanol, soluble in diethyl ether, acetone, benzene, chloroform and carbon disulfide, slightly soluble in water, soluble in hot water, insoluble in cold water, and capable of volatilizing with water vapor. Because of the physical characteristics of paeonol, paeonol in the water decoction can volatilize and escape along with the evaporated steam in the process of decompression and concentration, so that the content of the paeonol in the prepared six-ingredient rehmannia paste is reduced, and the quality of the product is influenced; in the traditional preparation of other Liuwei Dihuang preparation ointments, paeonol is extracted from moutan bark alone, and then the dregs are mixed with other medicinal materials for extraction. Traditional method preparation six ingredients rehmannia root paste need extract paeonol alone, has increased the production time and has reduced production efficiency simultaneously, for this reason, the utility model provides a can collect paeonol in the water decoction in the concentrated stage, reduce the equipment that six ingredients rehmannia root paste's supporting preparation method of paeonol loss in the technological process to improve production efficiency, reduction in production cost.

SUMMERY OF THE UTILITY MODEL

An object of the utility model is to provide a can decoct cortex moutan and other medicinal materials simultaneously and collect the equipment that the paeonol mixes with the concentrate extract and make six ingredients rehmannia root paste behind the separation of concentration stage.

The technical purpose of the utility model is realized by the following technical scheme:

the equipment for collecting paeonol by water extraction of the traditional Chinese medicine compound is characterized in that: consists of an extraction system, a concentration system and a nanofiltration membrane filtration system;

the extraction system comprises a hanging basket extraction tank, an extracting solution storage tank, a circulating pump and a conveying pump a, wherein an extraction basket for containing medicinal materials is arranged in the hanging basket extraction tank, a liquid outlet at the bottom of the hanging basket extraction tank is connected with an inlet of the circulating pump and an inlet of the conveying pump a through a three-way valve a, an outlet of the circulating pump is connected with a liquid inlet in the side wall of the hanging basket extraction tank, and an outlet of the conveying pump a is connected with a liquid inlet in the side wall of the extracting solution storage tank;

the concentration system comprises a scraper concentrator, a gas-liquid separator a, a condenser a, a condensed water liquid collecting tank, a condensed water storage tank, a delivery pump b, a discharge pump and a delivery pump c, wherein the inlet of the delivery pump b is connected with the liquid outlet at the bottom of the extracting solution storage tank through a valve b, the outlet of the delivery pump b is connected with the liquid inlet on the side wall of the scraper concentrator through a three-way valve b, the discharge outlet at the bottom of the scraper concentrator is connected with the discharge pump through a valve c, the steam outlet at the top of the scraper concentrator is connected with the inlet of the gas-liquid separator a, the outlet of the gas-liquid separator a is connected with the inlet of the condenser a, the liquid outlet at the bottom of the gas-liquid separator a is connected with an interface on the side wall of the scraper concentrator through a flange, the condenser a is arranged at the top of the condensed water liquid collecting tank and communicated with the condensed, the outlet of the delivery pump c is connected with the inlet of the condensed water storage tank through a cooler.

Receive filter membrane filtration system and include condensate water storage tank, delivery pump d and receive filter equipment of filter membrane, the import of delivery pump d is passed through valve e and is connected with the liquid outlet of condensate water storage tank, and the export of delivery pump d is passed through three-way valve d and is received the filter equipment inlet and be connected, receives filter equipment's liquid outlet and is connected with the inlet of condensate water storage tank, is received to be equipped with valve f on the discharge port of filter equipment bottom, and the export of delivery pump d is passed through three-way valve d and three-way valve b and scraper concentrator's inlet and delivery pump b's exit linkage.

Further, the extraction system still includes condenser b and vapour and liquid separator b, the import of condenser b is passed through three-way valve f and is connected with the export of circulating pump and the inlet that the hanging flower basket drawed on the jar lateral wall, still be equipped with three-way valve e on the pipeline between the import of condenser b and the three-way valve f, the export of condenser b passes through valve h and vapour and liquid separator b's access connection, and vapour and liquid separator b's export is connected with the backward flow mouth that sets up at the hanging flower basket extraction tank deck portion.

Furthermore, the extraction basket is of a multilayer structure, different types of medicinal materials are placed in a layered mode, and subsequent classification treatment of the medicine residues is facilitated.

Furthermore, a valve a is arranged on a pipeline between the three-way valve a and the delivery pump a, and the valve a is used for conveniently discharging the waste in the basket extraction tank out of the equipment.

Furthermore, the top of condenser b is equipped with the breather valve, and the cooling water entry on the condenser b sets up the top at condenser b, and the cooling water export on the condenser b sets up the bottom at condenser b.

Furthermore, the cooler is provided with a chilled water inlet and a chilled water outlet, the chilled water inlet is arranged at a position close to the bottom of the cooler, and the chilled water outlet is arranged at a position close to the top of the cooler.

To sum up, the utility model discloses following beneficial effect has: the device of the utility model can realize continuous production, continuous concentration and continuous discharge, optimizes the process that the paeonol is extracted and separated by adopting a steam distillation method firstly, cooled and crystallized, then the moutan bark dregs and other medicinal materials are decocted and concentrated to obtain extract, and then the separated paeonol crystal is mixed with the extract in the traditional preparation method; the preparation method using the equipment for production only needs one-time concentration, greatly shortens the production time, improves the production efficiency, can realize industrial continuous production, retains the active ingredients of paeonol of the moutan bark extract by using the equipment for production, has high paeonol transfer rate, and has important significance for fully utilizing medicinal material resources.

Drawings

FIG. 1 is a schematic structural diagram of the present invention;

FIG. 2 is a schematic view of an extraction tank;

in the figure, 101, a hanging basket extraction tank is arranged; 102, an extracting solution storage tank; 103: a scraper concentrator; 104: a gas-liquid separator a; 105: a condenser a; 106: a condensed water collection tank; 107: a condensed water storage tank; 108: a nanofiltration membrane filtering device; 109: a circulation pump; 110: a three-way valve a; 111: a valve a; 112: a delivery pump a; 113: a valve b; 114: a delivery pump b; 115: a three-way valve b; 116: a valve c; 117: a discharge pump; 118: a valve d; 119: a cooler; 120: a delivery pump c; 121: a valve e; 122: a three-way valve d; 123: a delivery pump d; 124: a valve f; 125: a chilled water inlet; 126: a chilled water outlet; 201: a condenser b; 202: a cooling water inlet; 203: a valve h; 204: a breather valve; 205: a three-way valve e; 206: a three-way valve f; 207: a cooling water outlet; 208: a gas-liquid separator b; 209: and (4) extracting the basket.

Detailed Description

The following describes the present invention in further detail with reference to the drawings and examples. It should be understood that the preferred embodiments described herein are for purposes of illustration and explanation only and are not intended to limit the present invention. Based on the embodiments in the present application, other embodiments obtained by a person skilled in the art without creative efforts belong to the scope of the present application.

As shown in figure 1, an apparatus for collecting paeonol by water extraction of a compound Chinese medicinal material comprises an extraction system, a scraper concentrator and a nanofiltration membrane filtration system; the extraction system includes that the hanging flower basket draws jar 101, extraction liquid storage tank 102, circulating pump 109 and delivery pump a112, the hanging flower basket draws jar 101 internally mounted has the basket 209 that draws that holds the medicinal material, the liquid outlet that the hanging flower basket drawed jar 101 bottom passes through three-way valve a110 and circulating pump 109's import and delivery pump a 112's access connection, and the export of circulating pump 109 and the hanging flower basket draw the inlet on the jar 101 lateral wall to be connected, the export of delivery pump a112 is connected with the inlet on the extraction liquid storage tank 102 lateral wall, the hanging flower basket draws jar 101 lateral wall to be equipped with the cavity, realizes heating it through inputing steam to the cavity.

As shown in fig. 1, the concentration system comprises a scraper concentrator 103, a gas-liquid separator a104, a condenser a105, a condensed water collecting tank 106, a condensed water storage tank 107, a delivery pump b114, a discharge pump 117 and a delivery pump c120, wherein an inlet of the delivery pump b114 is connected with a liquid outlet at the bottom of the extracting solution storage tank 102 through a valve b113, an outlet of the delivery pump b114 is connected with a liquid inlet at the side wall of the scraper concentrator 103 through a three-way valve b115, a discharge outlet at the bottom of the scraper concentrator 103 is connected with the discharge pump 117 through a valve c116, a steam outlet at the top of the scraper concentrator 103 is connected with an inlet of the gas-liquid separator a104, an outlet of the gas-liquid separator a104 is connected with an inlet of the condenser a105, a liquid outlet at the bottom of the gas-liquid separator a104 is connected with an interface on the side wall of the scraper concentrator 103 by a flange, the condenser, the nozzle arranged at the bottom of the condensed water collection tank 106 is connected with the inlet of a delivery pump c120 through a valve d118, and the outlet of the delivery pump c120 is connected with the inlet of a condensed water storage tank 107 through a cooler 119.

As shown in fig. 1, the nanofiltration membrane filtration system comprises a condensed water storage tank 107, a delivery pump d123 and a nanofiltration membrane filtration device 108, wherein an inlet of the delivery pump d123 is connected with a liquid outlet of the condensed water storage tank 107 through a valve e121, an outlet of the delivery pump d123 is connected with a liquid inlet of the nanofiltration membrane filtration device 108 through a three-way valve d122, a liquid outlet of the nanofiltration membrane filtration device 108 is connected with a liquid inlet of the condensed water storage tank 107, a discharge port at the bottom of the nanofiltration membrane filtration device 108 is provided with a valve f124, and an outlet of the delivery pump d123 is connected with a liquid inlet of the scraper concentrator 103 and an outlet of the delivery pump b114 through a three.

As shown in fig. 2, the extraction system further comprises a condenser b201 and a gas-liquid separator b208, an inlet of the condenser b201 is connected with an outlet of the circulating pump 109 and a liquid inlet on the side wall of the basket extraction tank 101 through a three-way valve f206, a three-way valve e205 is further arranged on a pipeline between the inlet of the condenser b201 and the three-way valve f206, an outlet of the condenser b201 is connected with an inlet of the gas-liquid separator b208 through a valve h203, and an outlet of the gas-liquid separator b208 is connected with a return port arranged at the top of the basket extraction tank 101.

Preferably, the extraction basket 209 has a multilayer structure, and different kinds of medicinal materials are placed in layers, so that subsequent classification treatment of the dregs of a decoction is facilitated.

Further, a valve a111 is arranged on a pipeline between the three-way valve a110 and the delivery pump a 112.

Furthermore, a breather valve 204 is arranged at the top of the condenser b201, a cooling water inlet 202 on the condenser b201 is arranged at the top of the condenser b201, and a cooling water outlet 207 on the condenser b201 is arranged at the bottom of the condenser b 201.

Further, the cooler 119 is provided with a chilled water inlet 125 and a chilled water outlet 126, the chilled water inlet 125 is provided with a position on the cooler 119 close to the bottom, and the chilled water outlet 126 is provided with a position on the cooler 119 close to the top.

The working principle of the extraction system is as follows: the pretreated medicinal materials are put into an extraction basket 209 and then are integrally placed in a basket extraction tank 101, a proper amount of water is injected into the basket extraction tank 101, steam (generated by a boiler) is turned on to heat, and when the water temperature rises to a set temperature, a three-way valve a110 and a three-way valve f206 are adjusted to be in internal circulation, and a circulating pump 109 is turned on to circulate the extracting solution. The water vapor generated in the extraction process flows into the condenser b202 through the gas-liquid separator b208 and the valve e is opened, and meanwhile, the cooling water flows in through the shell-side cooling water inlet 202 of the condenser b201 and flows out through the cooling water outlet 207. The extract steam is cooled by the condenser b202 to form condensed water, and when a certain amount of extract condensed water is collected, the extract condensed water is refluxed to the extraction tank 101 by the three-way valve e205 and the three-way valve f 206. A breather valve 204 on the condenser b201 ensures that the pressure of the whole system is in a normal pressure state during extraction. After extraction is finished, the three-way valve a110 is opened for external circulation, and the delivery pump a112 is opened to pump the extracting solution into the extracting solution storage tank 102, wherein the valve a111 is used for draining sewage when the tank body is cleaned.

The working principle of the scraper concentrator is as follows: after extraction is finished, a valve b113 and a three-way valve b115 are opened for internal circulation, a conveying pump b114 is opened to drive the extracting solution in the extracting solution storage tank 102 into a scraper concentrator 103 for concentration, steam condensate water flows into a condenser a105 through a gas-liquid separator a104 during concentration to be cooled to form steam condensate water, the condensate water is collected in a condensate water collecting tank 106, a valve d118 is opened after the condensate water reaches a certain storage amount, a negative pressure pump 120 is opened to drive the steam condensate water into a condensate water storage tank 107, and the temperature of the condensate water is high during continuous production and needs to be reduced through a cooler 119.

The nanofiltration membrane filtering system has the following working principle: after the condensed water storage tank 107 reaches a certain storage capacity, the valve e121 is opened, the delivery pump d123 and the three-way valve 122 are opened to adjust the internal circulation, the condensed water in the condensed water storage tank 107 is pumped into the nanofiltration device to be concentrated, the concentrated permeate liquid is discharged through the valve f124, the concentrated water returns to the condensed water storage tank 107, the filtration is continuously and repeatedly carried out, and the solubility of materials in the condensed water tank is improved. After the filtration is completed, the three-way valve d122 and the three-way valve b115 are adjusted to be in an external circulation mode, the concentrated water in the condensed water storage tank 107 is pumped into the scraper concentrator to be mixed, and after the concentrated water is mixed, the valve c116 and the discharging pump 117 are opened to pump out the materials.

Finally, it should be noted that: although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that changes may be made in the embodiments and/or equivalents thereof without departing from the spirit and scope of the invention. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. An apparatus for preparing six-ingredient rehmannia paste by extracting and separating paeonol from a compound Chinese medicinal water is characterized in that: consists of an extraction system, a concentration system and a nanofiltration membrane filtration system;

the extraction system comprises a hanging basket extraction tank (101), an extracting solution storage tank (102), a circulating pump (109) and a delivery pump a (112), wherein an extraction basket (209) for containing medicinal materials is arranged in the hanging basket extraction tank (101), a liquid outlet at the bottom of the hanging basket extraction tank (101) is connected with an inlet of the circulating pump (109) and an inlet of the delivery pump a (112) through a three-way valve a (110), an outlet of the circulating pump (109) is connected with a liquid inlet in the side wall of the hanging basket extraction tank (101), and an outlet of the delivery pump a (112) is connected with a liquid inlet in the side wall of the extracting solution storage tank (102);

the concentration system comprises a scraper concentrator (103), a gas-liquid separator a (104), a condenser a (105), a condensed water liquid collection tank (106), a condensed water storage tank (107), a delivery pump b (114), a discharge pump (117) and a delivery pump c (120), wherein an inlet of the delivery pump b (114) is connected with a liquid outlet at the bottom of the extracting solution storage tank (102) through a valve b (113), an outlet of the delivery pump b (114) is connected with a liquid inlet at the side wall of the scraper concentrator (103) through a three-way valve b (115), a discharge outlet at the bottom of the scraper concentrator (103) is connected with the discharge pump (117) through a valve c (116), a steam outlet at the top of the scraper concentrator (103) is connected with an inlet of the gas-liquid separator a (104), an outlet of the gas-liquid separator a (104) is connected with an inlet of the condenser a (105), a liquid outlet at the bottom of the gas-liquid separator a (104) is connected with an interface on the side, the condenser a (105) is arranged at the top of the condensed water collecting tank (106) and is communicated with the condensed water collecting tank (106), a pipe orifice arranged at the bottom of the condensed water collecting tank (106) is connected with an inlet of a delivery pump c (120) through a valve d (118), and an outlet of the delivery pump c (120) is connected with an inlet of a condensed water storage tank (107) through a cooler (119);

receive filter membrane filtration system includes condensate water storage tank (107), delivery pump d (123) and receive filter equipment (108) of filter membrane, the import of delivery pump d (123) is passed through valve e (121) and is connected with the liquid outlet of condensate water storage tank (107), the export of delivery pump d (123) is passed through three-way valve d (122) and is connected with receive filter equipment (108) inlet of filter membrane, receive the liquid outlet of filter equipment (108) of filter membrane and be connected with the inlet of condensate water storage tank (107), be equipped with valve f (124) on the discharge port of receive filter equipment (108) bottom of filter membrane, the export of delivery pump d (123) is passed through three-way valve d (122) and three-way valve b (115) and the inlet of scraper concentrator (103) and the exit linkage of delivery pump b (114).

2. The apparatus for preparing LIUWEIDIHUANG paste from paeonol extracted from Chinese medicinal compound water according to claim 1, which is characterized in that: the extraction system still includes condenser b (201) and vapour and liquid separator b (208), the import of condenser b (201) is passed through three-way valve f (206) and is drawed the export of circulating pump (109) and the hanging flower basket and be connected with the inlet on jar (101) lateral wall, still be equipped with three-way valve e (205) on the pipeline between the import of condenser b (201) and three-way valve f (206), the export of condenser b (201) is passed through valve h (203) and the access connection of vapour and liquid separator b (208), and the export of vapour and liquid separator b (208) is connected with the backward flow mouth that sets up at the hanging flower basket extraction jar (101) top.

3. The apparatus for preparing LIUWEIDIHUANG paste from paeonol extracted from Chinese medicinal compound water according to claim 1, which is characterized in that: the extraction basket (209) is of a multilayer structure.

4. The apparatus for preparing LIUWEIDIHUANG paste from paeonol extracted from Chinese medicinal compound water according to claim 1, which is characterized in that: and a valve a (111) is arranged on a pipeline between the three-way valve a (110) and the delivery pump a (112).

5. The apparatus for preparing LIUWEIDIHUANG paste from paeonol extracted from Chinese medicinal compound water according to claim 2, which is characterized in that: the top of condenser b (201) is equipped with breather valve (204), and cooling water inlet (202) on condenser b (201) set up the top at condenser b (201), and cooling water outlet (207) on condenser b (201) sets up the bottom at condenser b (201).

6. The apparatus for preparing LIUWEIDIHUANG paste from paeonol extracted from Chinese medicinal compound water according to claim 2, which is characterized in that: the cooler (119) is provided with a chilled water inlet (125) and a chilled water outlet (126), the chilled water inlet (125) is arranged at a position close to the bottom of the cooler (119), and the chilled water outlet (126) is arranged at a position close to the top of the cooler (119).