CN210842944U - Exposure-guiding type fluorescence endoscope system - Google Patents
Exposure-guiding type fluorescence endoscope system Download PDFInfo
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- CN210842944U CN210842944U CN201920176062.6U CN201920176062U CN210842944U CN 210842944 U CN210842944 U CN 210842944U CN 201920176062 U CN201920176062 U CN 201920176062U CN 210842944 U CN210842944 U CN 210842944U
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Abstract
The utility model discloses an exposure-guiding fluorescence endoscope system, which controls the exposure of a fluorescence camera through guiding light, so that the gray value of the output fluorescence image is kept consistent under different imaging distances between an endoscope and an observed tissue; the guide light source is controlled by the stroboscopic control device to carry out stroboscopic, so that the guide light source only plays a role in exposure guide and does not appear in a fluorescence imaging field of view, and the output effect of a fluorescence image is ensured.
Description
Technical Field
The utility model relates to an optical imaging field especially relates to a guide exposure type fluorescence endoscope system.
Background
Near-infrared fluorescent contrast agents are widely used in endoscopic imaging devices for intraoperative lymph labeling, tumor boundary targeting, angiography, cholangiography, and the like. However, in order to improve the signal-to-noise ratio and the signal-to-back ratio of the fluorescence image, the fluorescence camera often only or mainly receives the fluorescence signal collected by the endoscope, and the exposure parameter is adjusted according to the current fluorescence intensity, so that when an imaging object with weak fluorescence is observed close to a tissue, the exposure parameter of the camera is automatically increased, and the gray value of the fluorescence image is improved; when the observation is far away from the tissue, the exciting light irradiated to the imaging object is weak, the exposure parameters of the camera cannot be greatly improved any more, and the gray value of the fluorescence image is reduced. This makes the fluorescence image to be suddenly bright and suddenly dark, and far and near performance is inconsistent, influences doctor's judgement.
Accordingly, the prior art is yet to be improved and developed.
Disclosure of Invention
An object of the utility model is to provide a guide exposure type fluorescence endoscope system, the fluorescence signal that aims at solving current endoscope system output is along with the working distance change scintillation, can not satisfy and use the will to try to get the problem.
The technical scheme of the utility model as follows: a guidance exposure type fluorescence endoscope system comprises an excitation light source, a guidance light source, a light guide beam, an endoscope, a lens, a light filter, a fluorescence camera control module and a stroboscopic control device; the stroboscopic control device is connected with the guide light source, the stroboscopic control device is connected with the fluorescence camera, and the fluorescence camera is connected with the fluorescence camera control module;
the stroboscopic control device acquires a frame synchronization signal of the fluorescence camera, generates a time sequence control signal based on the frame synchronization signal of the fluorescence camera, and controls and guides the light source to carry out stroboscopic; excitation light emitted by the excitation light source and guiding light emitted by the guiding light source are transmitted through the light guide beam and coupled into the endoscope; the excitation light and the guiding light are emitted from the front end of the endoscope and reach the observed tissue, the excitation light and the guiding light reflected by the observed tissue and the fluorescence excited by the excitation light are collected by the endoscope and focused by the lens; wherein, the exciting light is blocked by the filter, and the guiding light and the fluorescence are transmitted through the filter to be imaged on the fluorescence camera; the fluorescence camera exposure module calculates exposure parameters according to the image brightness of the fluorescence image and the image brightness of the guiding light image, and inputs the calculated exposure parameters into the fluorescence camera to control the fluorescence camera to expose, so that the fluorescence brightness values of the images output by the fluorescence camera are kept consistent under different working distances of the endoscope from the observed tissue.
The guided exposure type fluorescence endoscope system further comprises an image processing module, wherein the image processing module is connected with the fluorescence camera and is connected with the stroboscopic control device; calculating exposure parameters in real time according to the guiding light image and the fluorescence image through a fluorescence camera control module, and controlling the fluorescence camera to perform exposure, so that the fluorescence brightness values of images output by the fluorescence camera are kept consistent under different working distances from the endoscope to an observed tissue; the stroboscopic control module controls and guides stroboscopic of the light source, and the image processing module outputs a fluorescent image meeting the requirements through algorithm processing.
The exposure guidance-type fluorescence endoscope system described above, wherein the brightness of the guidance light is stronger than the fluorescence brightness.
The guided exposure type fluorescence endoscope system is characterized in that the fluorescence camera is a rolling shutter, and the exposure is carried out by scanning line by line and line by line.
The utility model has the advantages that: the utility model provides a guide exposure type fluorescence endoscope system, which controls the exposure of a fluorescence camera through guiding light, so that the gray value of the output fluorescence image is kept consistent under different imaging distances between an endoscope and an observed tissue; the guide light source is controlled by the stroboscopic control device to carry out stroboscopic, so that the guide light source only plays a role in exposure guide and does not appear in a fluorescence imaging field of view, and the output effect of a fluorescence image is ensured.
Drawings
Fig. 1 is a schematic structural view of a middle guide exposure type fluorescence endoscope system according to the present invention.
Fig. 2 is a flowchart illustrating the steps of the exposure guidance method of the guided exposure type fluorescence endoscope system according to the present invention.
Fig. 3 is a graph of the fluorescence camera exposure guided by the embodiment 1 based on the guided light interval frame imaging.
Fig. 4 is a timing diagram of the embodiment 2 of the present invention for guiding the exposure of the fluorescence camera based on guiding light in the same frame.
Fig. 5 is a schematic diagram of the light guide imaging area for guiding the exposure of the fluorescence camera based on the same frame of light guide in the embodiment 2 of the present invention.
Detailed Description
Reference will now be made in detail to embodiments of the present invention, examples of which are illustrated in the accompanying drawings, wherein like reference numerals refer to the same or similar elements or elements having the same or similar function throughout. The embodiments described below with reference to the accompanying drawings are exemplary only for the purpose of explaining the present invention, and should not be construed as limiting the present invention.
In the description of the present invention, it is to be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and to simplify the description, but do not indicate or imply that the device or element referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore should not be construed as limiting the present invention. Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, features defined as "first", "second", may explicitly or implicitly include one or more of the described features. In the description of the present invention, "a plurality" means two or more unless specifically limited otherwise.
In the description of the present invention, it is to be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "connected," and "connected" are to be construed broadly, and may be, for example, fixedly connected, detachably connected, or integrally connected; may be mechanically connected, may be electrically connected or may be in communication with each other; either directly or indirectly through intervening media, either internally or in any other relationship. The specific meaning of the above terms in the present invention can be understood according to specific situations by those skilled in the art.
In the present disclosure, unless expressly stated or limited otherwise, the first feature "on" or "under" the second feature may comprise direct contact between the first and second features, or may comprise contact between the first and second features not directly. Also, the first feature being "on," "above" and "over" the second feature includes the first feature being directly on and obliquely above the second feature, or merely indicating that the first feature is at a higher level than the second feature. A first feature being "under," "below," and "beneath" a second feature includes the first feature being directly under and obliquely below the second feature, or simply meaning that the first feature is at a lesser elevation than the second feature.
The following disclosure provides many different embodiments or examples for implementing different features of the invention. In order to simplify the disclosure of the present invention, the components and arrangements of specific examples are described below. Of course, they are merely examples and are not intended to limit the present invention. Furthermore, the present invention may repeat reference numerals and/or reference letters in the various examples, which have been repeated for purposes of simplicity and clarity and do not in themselves dictate a relationship between the various embodiments and/or arrangements discussed. In addition, the present disclosure provides examples of various specific processes and materials, but one of ordinary skill in the art may recognize applications of other processes and/or use of other materials.
As shown in fig. 1, a fluorescence endoscope system of a guided exposure type includes an excitation light source 1, a guided light source 2, a light guide beam 3, an endoscope 4, a lens 5, a filter 6, a fluorescence camera 7, a fluorescence camera control module 8, and a strobe control device 9; the stroboscopic control device 9 is connected with the guide light source 2, the stroboscopic control device 9 is connected with the fluorescence camera 7, and the fluorescence camera 7 is connected with the fluorescence camera control module 8;
the stroboscopic control device 9 acquires a frame synchronization signal of the fluorescence camera 7, generates a time sequence control signal based on the frame synchronization signal of the fluorescence camera 7, and controls the guidance light source 2 to strobe, so that the guidance light source 2 only plays a role in exposure guidance and does not appear in a fluorescence imaging field of view; excitation light emitted by the excitation light source 1 and guiding light emitted by the guiding light source 2 are transmitted through the light guide beam 3 and coupled into the endoscope 4; the excitation light and the guiding light are emitted from the front end of the endoscope 3 and reach the tissue to be observed, the excitation light and the guiding light reflected by the tissue to be observed, and the fluorescence excited by the excitation light are simultaneously collected by the endoscope 4 and focused by the lens 5; wherein, the exciting light is blocked by the filter 6, and the guiding light and the fluorescence are transmitted through the filter 6 to be imaged on the fluorescence camera 7; the fluorescence camera exposure module 8 calculates exposure parameters according to the image brightness of the fluorescence image and the guiding light image, and inputs the calculated exposure parameters into the fluorescence camera 7 to control the fluorescence camera 7 to expose, so that the fluorescence brightness values of the images output by the fluorescence camera 7 are kept consistent under different working distances from the endoscope 4 to the observed tissue; the guiding light source 2 provides guiding light which is directly reflected by the observed tissue and then enters the fluorescence camera 7, and the fluorescence camera 7 is controlled to perform automatic exposure; for example, when the endoscope 4 is closer to the tissue to be observed, the optical density is high, and the fluorescence camera 7 automatically lowers the gain and the exposure time; when the endoscope 4 is far away from the observed tissue, the fluorescence camera 7 automatically increases the gain and the exposure time; so that the brightness of the image illuminated by the guiding light is kept consistent under different working distances from the endoscope 4 to the observed tissue; meanwhile, the automatic exposure parameters of the fluorescence camera 7 also enable the brightness of the fluorescence image to be kept consistent; in general, the fluorescence camera 7 is automatically exposed by the light guide, and the automatic exposure enables the fluorescence image brightness to be kept relatively consistent under different working distances of the endoscope 4 from the observed tissue.
Specifically, the guided exposure type fluorescence endoscope system further comprises an image processing module 10, wherein the image processing module 10 is connected with the fluorescence camera 7, and the image processing module 10 is connected with the strobe control device 9; calculating exposure parameters in real time according to the guiding light image and the fluorescence image through a fluorescence camera control module 8, and controlling the fluorescence camera 7 to perform exposure, so that the fluorescence brightness values of the images output by the fluorescence camera 7 are kept consistent under different working distances from the endoscope 3 to the observed tissue; the stroboscopic control module 9 controls and guides the stroboscopic of the light source 2, and the image processing module 10 outputs a fluorescent image meeting the requirements through algorithm processing.
As shown in fig. 2, the method for guiding exposure of the fluorescence endoscope system of the guided exposure type includes the following steps:
step S1: the stroboscopic control device 9 acquires a frame synchronization signal of the fluorescence camera 7, generates a time sequence control signal based on the frame synchronization signal of the fluorescence camera 7, and controls the guidance light source 2 to strobe, so that the guidance light source 2 only plays a role in exposure guidance and does not appear in a fluorescence imaging field of view;
step S2: excitation light emitted by the excitation light source 1 and guiding light emitted by the guiding light source 2 are transmitted through the light guide beam 3 and coupled into the endoscope 4;
step S3: the excitation light and the guiding light are emitted from the front end of the endoscope 3 and reach the tissue to be observed, the excitation light and the guiding light reflected by the tissue to be observed, and the fluorescence excited by the excitation light are simultaneously collected by the endoscope 4 and focused by the lens 5;
step S4: the exciting light is blocked by the filter 6, and the guiding light and the fluorescence are transmitted through the filter 6 to be imaged on the fluorescence camera 7;
step S5: the fluorescence camera exposure module 8 calculates exposure parameters according to the image brightness of the fluorescence image and the guiding light image, and inputs the calculated exposure parameters into the fluorescence camera 7 to control the fluorescence camera 7 to perform exposure, so that the fluorescence brightness values of the images output by the fluorescence camera 7 are kept consistent under different working distances from the endoscope 4 to the observed tissue.
Specifically, the method for guiding exposure of the fluorescence endoscope system of the guided exposure type further comprises the following steps: step S6: the image processing module 10 outputs a fluorescent image meeting the requirements through algorithm processing.
Specifically, in the steps S1 to S6, the strobe control device 9 controls the guidance light source 2 to adopt different stroboscopic modes, so that the guidance light source 2 only plays a role of exposure guidance and does not appear in the fluorescence imaging field of view:
example 1
Because the distances between the front end of the endoscope 4 and the observed tissue are different, the illumination areas are different, and the light power per unit area is correspondingly changed, so that the intensity of the guiding light imaged on the fluorescent camera 7 is different, and the fluorescent camera control module 8 calculates different exposure parameters; when the distance is short, the light power of the unit area is large, the exposure parameter calculated by the fluorescence camera control module 8 is small, and when the distance is long, the light power of the unit area is small, the exposure parameter calculated by the fluorescence camera control module 8 is large, so that the brightness values of the fluorescence images are kept relatively consistent.
As shown in fig. 3, the strobe control device 9 acquires a frame synchronization signal of the fluorescence camera 7, generates a timing control signal based on the frame synchronization signal of the fluorescence camera 7, and controls the guiding light source 2 to perform frame stroboflash according to the frame synchronization signal, so that two adjacent frames of the continuous image of the fluorescence camera 7 are a fluorescence image and a guiding light mixed fluorescence image respectively, and input the fluorescence images into the image processing module 10; the image processing module 10 extracts the fluorescence images at intervals of frames through algorithm processing, abandons the guiding light mixed fluorescence image, and finally outputs only the fluorescence image, and the fluorescence brightness of the fluorescence image is kept consistent under the guidance of the exposure of the guiding light.
Preferably, the brightness of the guiding light is stronger than the fluorescence brightness, and the guiding light guides the exposure calculation of the fluorescence camera control module 8.
In the embodiment, the fluorescent camera control module 8 calculates the exposure parameters in real time according to the guiding light image and the fluorescent image, and controls the fluorescent camera 7 to perform exposure, so that the fluorescent brightness values of the output fluorescent image are kept relatively consistent under different working distances from the endoscope 3 to the observed tissue; the stroboscopic control module 9 controls and guides the light source 2 to strobe at intervals of frames, the image processing module 10 extracts the fluorescence image at intervals of frames through algorithm processing, and finally only the fluorescence image is output.
Example 2
Because the distances between the front end of the endoscope 4 and the observed tissue are different, the illumination areas are different, and the light power per unit area is correspondingly changed, so that the intensity of the guiding light imaged on the fluorescent camera 7 is different, and the fluorescent camera control module 8 calculates different exposure parameters; when the distance is short, the light power per unit area is large, the exposure parameter calculated by the fluorescence camera control module 8 is small, and when the distance is long, the light power per unit area is small, the exposure parameter calculated by the fluorescence camera control module 8 is large, so that the brightness values of the output fluorescence images are kept consistent.
As shown in fig. 4, the strobe control device 9 acquires the frame synchronization signal of the fluorescence camera 7, generates the timing control signal based on the frame synchronization signal of the fluorescence camera 7 to control the guidance light source 2 to strobe at a specific duty ratio, and sets the exposure time of the fluorescence camera 7 so that the guidance light is exposed only at the pixels in the edge area of the fluorescence imaging field, as shown in fig. 5; after receiving the image of the fluorescence camera 7, the image processing module 10 cuts out the area without light exposure from the image through algorithm processing and outputs the area as a fluorescence image.
The fluorescent camera 7 is a rolling shutter, and performs exposure line by line scanning.
Preferably, the brightness of the guiding light is stronger than the fluorescence brightness, and the guiding light guides the exposure calculation of the fluorescence camera control module 8.
In the embodiment, the fluorescent camera control module 8 calculates exposure parameters in real time according to the guiding light image and the fluorescent image, and controls the fluorescent camera 7 to perform exposure, so that the fluorescent brightness values of the fluorescent image are kept relatively consistent under different distances from the endoscope 3 to the observed tissue; the stroboscopic control module 9 controls the guiding light source 2 to strobe according to a specific duty ratio, the exposure time of the fluorescent camera 7 is set, so that the guiding light is only exposed in the pixels of the edge area of the fluorescent imaging view field, after the image processing module 10 receives the image of the fluorescent camera 7, the non-guiding light exposure area is intercepted from the image and is used as a fluorescent image to be output and processed by an algorithm through algorithm processing, and the non-guiding light exposure area is intercepted from the image and is used as a fluorescent image to be output by the image processing module 10.
In the description herein, references to the description of the terms "one embodiment," "certain embodiments," "an illustrative embodiment," "an example," "a specific example," or "some examples," etc., mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the invention. In this specification, schematic representations of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.
It is to be understood that the invention is not limited to the above-described embodiments, and that modifications and variations may be made by those skilled in the art in light of the above teachings, and all such modifications and variations are intended to be included within the scope of the invention as defined in the appended claims.
Claims (4)
1. A guidance exposure type fluorescence endoscope system is characterized by comprising an excitation light source, a guidance light source, a light guide beam, an endoscope, a lens, a light filter, a fluorescence camera control module and a stroboscopic control device; the stroboscopic control device is connected with the guide light source, the stroboscopic control device is connected with the fluorescence camera, and the fluorescence camera is connected with the fluorescence camera control module;
the stroboscopic control device acquires a frame synchronization signal of the fluorescence camera, generates a time sequence control signal based on the frame synchronization signal of the fluorescence camera, and controls and guides the light source to carry out stroboscopic; excitation light emitted by the excitation light source and guiding light emitted by the guiding light source are transmitted through the light guide beam and coupled into the endoscope; the excitation light and the guiding light are emitted from the front end of the endoscope and reach the observed tissue, the excitation light and the guiding light reflected by the observed tissue and the fluorescence excited by the excitation light are collected by the endoscope and focused by the lens; wherein, the exciting light is blocked by the filter, and the guiding light and the fluorescence are transmitted through the filter to be imaged on the fluorescence camera; the fluorescence camera exposure module calculates exposure parameters according to the image brightness of the fluorescence image and the image brightness of the guiding light image, and inputs the calculated exposure parameters into the fluorescence camera to control the fluorescence camera to expose, so that the fluorescence brightness values of the images output by the fluorescence camera are kept consistent under different working distances of the endoscope from the observed tissue.
2. The guided exposure fluorescence endoscope system of claim 1, further comprising an image processing module, wherein the image processing module is connected to the fluorescence camera, and the image processing module is connected to the strobe control device; calculating exposure parameters in real time according to the guiding light image and the fluorescence image through a fluorescence camera control module, and controlling the fluorescence camera to perform exposure, so that the fluorescence brightness values of images output by the fluorescence camera are kept consistent under different working distances from the endoscope to an observed tissue; the stroboscopic control module controls and guides stroboscopic of the light source, and the image processing module outputs a fluorescent image meeting the requirements through algorithm processing.
3. The guided exposure fluorescence endoscope system according to any one of claims 1 or 2, wherein the brightness of the guided light is stronger than the fluorescence brightness.
4. The guided exposure fluorescence endoscope system according to any one of claims 1 or 2, wherein the fluorescence camera is a rolling shutter, and the exposure is performed line by line scanning.
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