CN210803493U - Combined detection device for transferrin, hemoglobin and helicobacter pylori antigen - Google Patents
Combined detection device for transferrin, hemoglobin and helicobacter pylori antigen Download PDFInfo
- Publication number
- CN210803493U CN210803493U CN201921185343.4U CN201921185343U CN210803493U CN 210803493 U CN210803493 U CN 210803493U CN 201921185343 U CN201921185343 U CN 201921185343U CN 210803493 U CN210803493 U CN 210803493U
- Authority
- CN
- China
- Prior art keywords
- detection
- test strip
- sample
- transferrin
- hemoglobin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Images
Abstract
The utility model relates to a combined detection device for transferrin, hemoglobin and helicobacter pylori antigens. The joint detection device comprises a sample collection accommodating part and a sample detection part, wherein a sealing element is arranged at the bottom of the sample collection accommodating part, the sample detection part comprises a detection container, a detection test strip assembly and a puncture mechanism, the detection test strip assembly is arranged in the detection container, the puncture mechanism is arranged in the detection container, the sample collection accommodating part can be inserted into the detection container along the axial direction of the detection container, and when the sample collection accommodating part moves towards the puncture mechanism along the axial direction, the puncture mechanism can puncture the sealing element, so that a sample to be detected in the sample collection accommodating part enters the detection container, and the sample to be detected can contact the detection test strip assembly. The utility model discloses a combined detection device of transferrin, hemoglobin and helicobacter pylori antigen can detect transferrin, hemoglobin and helicobacter pylori antigen simultaneously.
Description
Technical Field
The utility model relates to an external diagnosis technical field especially relates to a combined detection device of transferrin, hemoglobin and helicobacter pylori antigen.
Background
The detection of occult blood in stool has important value for the diagnosis of chronic gastrointestinal hemorrhage and the screening of malignant large intestine tumor. The indexes of the occult blood of the excrement detected by the conventional immunoassay method are hemoglobin and transferrin, and the hemoglobin and the transferrin in the excrement can be simultaneously detected by applying a combined immunoassay method, so that the positive detection rate of digestive tract hemorrhagic diseases is obviously improved.
Helicobacter pylori is a gram-negative microaerophilic bacterium which is parasitic in the stomach and duodenum, and its infection is very common, with a global natural population infection rate of more than 50%, and the route of transmission is presumed to be oral infection.
Helicobacter pylori infection is an infectious disease, and can cause chronic gastritis, peptic ulcer and the like, common symptoms comprise discomfort of the upper stomach, pain, flatulence, anorexia, nausea, vomiting, dark or tar-colored feces and the like, and more than 70 percent of infected people have no obvious symptoms. Helicobacter pylori is a main pathogenic factor of gastritis and peptic ulcer, is closely related to the occurrence of functional dyspepsia, gastric mucosa-associated lymphoblastic lymphoma and gastric cancer, and is listed as a class I carcinogenic factor by the international cancer research organization of the world health organization.
Eradication of H.pylori can significantly reduce the incidence of gastric and duodenal diseases, and can reduce new cases of H.pylori infection in the future. At present, the gold standard for detecting helicobacter pylori is a bacteria isolation culture technology, but the gold standard is not easy to popularize due to high experimental conditions and technical requirements. And the detection of the helicobacter pylori antigen in the excrement does not need expensive equipment, is convenient to operate and interpret results, has good sensitivity and specificity, and is increasingly popularized.
At present, the fecal detection device is provided with a combined detection device for transferrin and hemoglobin, but a combined detection device capable of simultaneously detecting transferrin, hemoglobin and helicobacter pylori antigens is lacked.
SUMMERY OF THE UTILITY MODEL
Based on the above-mentioned defect among the prior art, the utility model aims to provide a can detect jointly detection device of transferrin, hemoglobin and helicobacter pylori antigen simultaneously.
Therefore, the utility model provides the following technical scheme.
The utility model provides a combined detection device of transferrin, hemoglobin and helicobacter pylori antigen, which comprises a sample collecting and accommodating part and a sample detection part,
the sample collection containing part is used for collecting and containing a sample to be detected, a sealing element is arranged at the bottom of the sample collection containing part,
the sample detection part comprises a detection container, a detection test strip component and a puncture mechanism,
the detection test strip component is arranged in the detection container and is used for simultaneously detecting the transferrin, the hemoglobin and the helicobacter pylori antigen,
the puncturing mechanism is arranged in the detection container,
the sample collection container is insertable in the detection container in an axial direction thereof, and
when the sample collection accommodating part moves towards the puncture mechanism along the axial direction, the puncture mechanism can puncture the sealing element, so that the sample to be detected in the sample collection accommodating part enters the detection container, and the sample to be detected can contact the detection test strip assembly.
In at least one embodiment, the sample collection receptacle comprises a collection wand and a sample container, the collection wand being insertable into the sample container, the sealing element being disposed at the bottom of the sample container.
In at least one embodiment, the sample detection portion further comprises a strip mounting bracket inserted into the detection container, the detection strip assembly being disposed on the strip mounting bracket.
In at least one embodiment, the test strip mounting rack is provided with a mounting groove, the mounting groove extends along the axial direction, and the test strip assembly is disposed in the mounting groove.
In at least one embodiment, the piercing mechanism is disposed at the bottom of the test receptacle.
In at least one embodiment, at least a wall portion of the test container corresponding to the test strip assembly is a transparent wall portion.
In at least one embodiment, the test strip assembly comprises a transferrin and hemoglobin combined test strip for detecting the transferrin and the hemoglobin and a helicobacter pylori antigen test strip for detecting the helicobacter pylori antigen.
In at least one embodiment, the transferrin and hemoglobin combination test strip comprises a first bottom plate, a first water absorbent plate, a first nitrocellulose membrane, a first sample liquid absorbing layer, and a first color particle storage pad containing transferrin monoclonal antibody and hemoglobin monoclonal antibody,
and the first nitrocellulose membrane is loaded with a transferrin monoclonal antibody detection line, a hemoglobin monoclonal antibody detection line and a goat anti-mouse polyclonal antibody control line which are separated from each other.
In at least one embodiment, the test strip components include a transferrin test strip, a hemoglobin test strip, and a helicobacter pylori antigen test strip,
the transferrin detection test strip is used for detecting the transferrin,
the hemoglobin detection test strip is used for detecting the hemoglobin,
the test paper strip for detecting the helicobacter pylori antigen is used for detecting the helicobacter pylori antigen.
In at least one embodiment, the test strip for detecting helicobacter pylori antigen comprises a second bottom plate, a second water absorption plate, a second nitrocellulose membrane, a second sample liquid absorption layer and a second color particle storage pad containing the monoclonal antibody of helicobacter pylori antigen and the conjugate of biotin-bovine serum albumin,
the second nitrocellulose membrane is loaded with a helicobacter pylori antigen monoclonal antibody detection line and a goat anti-mouse polyclonal antibody and streptavidin control line which are separated from each other.
Through adopting the technical scheme, the utility model provides a combined detection device of transferrin, hemoglobin and helicobacter pylori antigen can detect transferrin, hemoglobin and helicobacter pylori antigen simultaneously through setting up the detection test paper strip subassembly that can detect transferrin, hemoglobin and helicobacter pylori antigen simultaneously.
Drawings
Fig. 1 shows a schematic structural diagram of a first embodiment of the combined detection device for transferrin, hemoglobin and helicobacter pylori antigen according to the present invention.
Fig. 2 shows an exploded view of the sample collection container of fig. 1.
Fig. 3 shows a cross-sectional view of the sample collection well of fig. 1.
Fig. 4 shows an exploded view of the sample-detecting part in fig. 1.
Fig. 5 shows a cross-sectional view of the detection vessel of fig. 4.
FIG. 6 shows a schematic structural diagram of the transferrin and hemoglobin combined test strip in FIG. 4.
Fig. 7 shows a cross-sectional view of fig. 6.
FIG. 8 shows a schematic structural diagram of the test strip for helicobacter pylori antigen detection in FIG. 4.
Fig. 9 shows a cross-sectional view of fig. 8.
Fig. 10 shows a schematic structural diagram of a test strip assembly and a test strip mounting rack in a second embodiment of the combined detection device for transferrin, hemoglobin and helicobacter pylori antigen according to the present invention.
Description of the reference numerals
1 a sample collection container; 11 collecting rod; 12 a sample container; 121 a chamber; 13, sealing rings; 14 a sealing element;
2 a sample detection section; 21 detecting the container; 22 a test strip mounting rack; 221, installing a groove; 23 detecting the test strip component;
231 transferrin and hemoglobin combined test strip; 2311 a first base plate; 2312 a first water absorption plate; 2313 a first nitrocellulose membrane; 23131 detecting transferrin monoclonal antibody; 23132 detecting hemoglobin monoclonal antibody; 23133 controlling goat anti-mouse polyclonal antibody line; 2314 absorbing the first sample liquid layer; 2315 a first color particle storage pad;
232 helicobacter pylori antigen detection test paper; 2321 a second base plate; 2322 a second suction plate; 2323 a second nitrocellulose membrane; 23231 detecting helicobacter pylori antigen monoclonal antibody; 23232 goat anti-mouse polyclonal antibody and streptavidin control line; 2324 a second sample pipette layer; 2325 a second color particle storage pad;
24 a lancing mechanism; 241 sharp part; 242 through holes;
25 testing the test strip assembly; 251 transferrin detection test strip; 252 a hemoglobin test strip; 253 helicobacter pylori antigen test strip.
Detailed Description
Exemplary embodiments of the present invention are described below with reference to the accompanying drawings. It should be understood that the detailed description is only intended to teach one skilled in the art how to practice the invention, and is not intended to exhaust all possible ways of practicing the invention, nor is it intended to limit the scope of protection of the invention.
(first embodiment)
The first embodiment of the combined detection device for transferrin, hemoglobin and helicobacter pylori antigen according to the present invention is described in detail below with reference to fig. 1 to 9.
In the present embodiment, as shown in fig. 1, the device for combined detection of transferrin, hemoglobin and helicobacter pylori antigen according to the present invention comprises a sample collection container 1 and a sample detection unit 2. The sample collection container 1 is insertable into the sample detection unit 2 along an axial direction (longitudinal direction) of the sample detection unit 2, and is used for collecting and containing a sample to be detected (for example, feces).
In the present embodiment, as shown in fig. 1 and 2, the sample collection container 1 includes a collection rod 11, a sample container 12, a packing 13, and a seal member 14. Wherein the collecting rod 11 is used for collecting a sample to be detected.
In the present embodiment, as shown in fig. 3, the collection rod 11 is inserted into the sample container 12, the sample container 12 has a chamber 121 for containing a diluting solution, and a seal ring 13 is provided between the collection rod 11 and the sample container 12. In this way, the sealing ring 13 can seal the chamber 121 of the sample container 12, so as to prevent the diluting solution in the chamber 121 from entering the chamber above the chamber 121 during transportation, thereby ensuring that the amount of the diluting solution is sufficient.
In this embodiment, a sealing element 14 is provided at the bottom of the sample container 12 for sealing the chamber 121. Wherein the sealing element 14 may be a sealing aluminum foil, which may be heat sealed to the bottom of the sample container 12.
In the present embodiment, as shown in fig. 1, 4 and 5, the sample detection part 2 includes a detection container 21, a strip mounting bracket 22, a detection strip assembly 23 and a puncture mechanism 24.
In the present embodiment, as shown in fig. 4, the detection container 21 has a cylindrical shape, and the cross section of the detection container 21 has a substantially rectangular shape.
In the present embodiment, as shown in fig. 4, the strip mounting bracket 22 is provided with two mounting grooves 221, and the two mounting grooves 221 extend in parallel in the axial direction (longitudinal direction) of the detection container 21. The strip mounting bracket 22 is inserted into the detection container 21.
In this embodiment, as shown in FIG. 4, the test strip assembly 23 includes a transferrin and hemoglobin combination test strip 231 and a helicobacter pylori antigen test strip 232. Wherein, the transferrin and hemoglobin combined test strip 231 and the helicobacter pylori antigen test strip 232 are respectively arranged in the corresponding mounting grooves 221.
In the present embodiment, the wall portion of the detection container 21 corresponding to the test strip assembly 23 is a transparent wall portion. Of course, the present invention is not limited thereto, and the entire side wall portion of the detection container 21 may be transparent.
In the present embodiment, one end (the end having the liquid absorbent layer) of the test strip assembly 23 extends to the bottom of the test container 21. In this way, the test strip assembly 23 can be easily contacted with the sample solution, thereby reducing the amount of sample solution required.
In the present embodiment, as shown in fig. 5, the puncturing means 24 is provided at the bottom of the detection container 21.
The pricking mechanism 24 has a sharp portion 241 (blade portion) and a through hole 242. The sharp portion 241 is used to pierce the sealing member 14, the through hole 242 is used to accommodate the lower portion of the collecting rod 11, and a space for accommodating the sidewall of the sample container 12 is provided between the outer periphery of the piercing mechanism 24 and the inner wall surface of the detection container 21. In this way, the axial dimension of the sample collection container can be reduced, and the axial dimension of the entire joint detection device can be reduced.
In this embodiment, as shown in fig. 6 and 7, the transferrin and hemoglobin combination test strip 231 comprises a first bottom sheet 2311, a first absorbent sheet 2312, a first nitrocellulose membrane 2313, a first sample liquid absorbent layer 2314, and a first color particle storage pad 2315 containing transferrin mab and hemoglobin mab.
The first water absorption plate 2312 and the first sample liquid absorption layer 2314 are respectively arranged at two ends of the first bottom plate 2311, two ends of the first nitrocellulose membrane 2313 are respectively connected with the first water absorption plate 2312 and the first color particle storage pad 2315, one end of the first sample liquid absorption layer 2314 is connected with the first color particle storage pad 2315, and the first nitrocellulose membrane 2313 is loaded with a transferrin monoclonal antibody detection line 23131, a hemoglobin monoclonal antibody detection line 23132 and a goat anti-mouse polyclonal antibody control line 23133 which are separated from each other.
In this embodiment, as shown in fig. 8 and 9, the test strip 232 for detecting helicobacter pylori antigen includes a second bottom plate 2321, a second water absorption plate 2322, a second nitrocellulose membrane 2323, a second sample liquid absorption layer 2324, and a second color particle storage pad 2325 containing a monoclonal antibody of helicobacter pylori antigen and a conjugate of biotin-BSA (Bovine Serum Albumin).
The second water absorption plate 2322 and the second sample liquid absorption layer 2324 are respectively disposed at two ends of the second bottom plate 2321, two ends of the second nitrocellulose membrane 2323 are respectively connected to the second water absorption plate 2322 and the second color particle storage pad 2325, one end of the second sample liquid absorption layer 2324 is connected to the second color particle storage pad 2325, and the second nitrocellulose membrane 2323 is loaded with a helicobacter pylori antigen monoclonal antibody detection line 23231, a goat anti-mouse polyclonal antibody and a streptavidin control line 23232, which are separated from each other.
In the present embodiment, the color particles may be colloidal gold particles, and accordingly, the first and second color particle storage pads 2315 and 2325 may be gold-labeled pads.
The operation of the device for the combined detection of transferrin, hemoglobin and helicobacter pylori antigen according to the present invention will be described below.
In the present embodiment, when a sample to be tested (for example, feces) needs to be tested, the sample to be tested may be collected using the collection rod 11 in the sample collection container 1, and then the collection rod 11 is inserted into the sample container 12, and the sample container 12 is shaken so that the sample to be tested is diluted uniformly.
After the shaking is completed, the sample collection container 1 is inserted into the sample detection part 2 along the axial direction of the sample detection part 2 until the piercing mechanism 24 pierces the sealing member 14 at the bottom of the sample collection container 1, and the sample solution in the sample collection container 1 flows into the detection container 21 (at this time, the lower portion of the collection rod 11 is located in the through hole 242, and the lower side wall of the sample container 12 is located between the outer periphery of the piercing mechanism 24 and the inner wall surface of the detection container 21).
Further, the sample solution containing the sample to be tested will be contacted with the test strip assembly 23 such that the individual detection lines and/or control lines of the test strip assembly 23 are colored (e.g., red). The inspector can observe the inspection result through the transparent wall portion of the inspection container 21.
Specifically, for the test strip 231 for combined detection of transferrin and hemoglobin, if only the goat anti-mouse polyclonal antibody control line 23133 is developed, it indicates that the content of transferrin and hemoglobin in the sample to be detected does not exceed the predetermined value, and the detection results of transferrin and hemoglobin are negative.
If the transferrin monoclonal antibody detection line 23131 and the goat anti-mouse polyclonal antibody control line 23133 are colored, the content of transferrin in the sample to be detected exceeds a preset value, the detection result of transferrin is positive, and the detection result of hemoglobin is negative.
If the hemoglobin monoclonal antibody detection line 23132 and the goat anti-mouse polyclonal antibody control line 23133 are colored, the content of hemoglobin in the sample to be detected exceeds a preset value, the detection result of hemoglobin is positive, and the detection result of transferrin is negative.
If the transferrin monoclonal antibody detection line 23131, the hemoglobin monoclonal antibody detection line 23132 and the goat anti-mouse polyclonal antibody control line 23133 are all colored, the content of transferrin and hemoglobin in the sample to be detected exceeds a preset value, and the detection results of transferrin and hemoglobin are positive.
If the transferrin monoclonal antibody detection line 23131, the hemoglobin monoclonal antibody detection line 23132 and the goat anti-mouse polyclonal antibody control line 23133 are not colored, the detection fails (possibly the combined detection device is damaged or the detection operation is wrong, etc.).
It will be appreciated that a positive test for either of transferrin and hemoglobin indicates bleeding from the digestive tract.
As for the test paper strip 232 for detecting the helicobacter pylori antigen, if only the goat anti-mouse polyclonal antibody and the streptavidin control line 23232 are developed, the content of the helicobacter pylori antigen in the sample to be detected does not exceed the predetermined value, and the detection results of the helicobacter pylori antigen are all negative.
If the helicobacter pylori antigen monoclonal antibody detection line 23231 and the goat anti-mouse polyclonal antibody and the streptavidin control line 23232 both develop color, the content of the helicobacter pylori antigen in the sample to be detected exceeds a preset value, and the detection result of the helicobacter pylori antigen is positive.
If the detection line 23231 for the monoclonal antibody of the helicobacter pylori antigen and both the goat anti-mouse polyclonal antibody and the streptavidin control line 23232 do not develop color, the detection fails (possibly, the combined detection device is damaged or the detection operation is wrong, etc.).
(second embodiment)
The second embodiment of the combined detection device for transferrin, hemoglobin and helicobacter pylori antigen according to the present invention is described in detail below with reference to fig. 10.
The structures of the sample collection and storage section and the sample detection section in the present embodiment are basically the same as those in the first embodiment. The difference is mainly that, as shown in fig. 10, the number of the mounting grooves 221 on the test strip mounting rack 22 in the present embodiment is three.
Accordingly, in this embodiment, as shown in FIG. 10, the test strip assembly 25 includes a transferrin test strip 251, a hemoglobin test strip 252, and a helicobacter pylori antigen test strip 253. Wherein, the transferrin test strip 251, the hemoglobin test strip 252 and the helicobacter pylori antigen test strip 253 are respectively arranged in the corresponding mounting grooves 221.
In this embodiment, the transferrin test strip 251 and the hemoglobin test strip 252 are similar in structure to the transferrin and hemoglobin combined test strip 231 of the first embodiment. That is, the transferrin detection test strip 251 includes a third base plate, a third water absorption plate, a third nitrocellulose membrane, a third sample liquid absorption layer, and a third color particle storage pad, and the hemoglobin detection test strip 252 includes a fourth base plate, a fourth water absorption plate, a fourth nitrocellulose membrane, a fourth sample liquid absorption layer, and a fourth color particle storage pad, and the connection structure between the respective portions is the same as that in the first embodiment.
The difference is mainly that the third color particle storage pad in the transferrin detection test strip 251 in this embodiment contains only transferrin monoclonal antibody, and does not contain hemoglobin monoclonal antibody. The third nitrocellulose membrane in the transferrin detection test strip 251 is only provided with a transferrin monoclonal antibody detection line and a goat anti mouse polyclonal antibody control line which are separated from each other, and is not provided with a hemoglobin monoclonal antibody detection line.
The fourth color particle storage pad of the hemoglobin detection test strip 252 of this embodiment contains only hemoglobin monoclonal antibody and does not contain transferrin monoclonal antibody. The fourth nitrocellulose membrane in the hemoglobin detection test strip 252 is only provided with a hemoglobin monoclonal antibody detection line and a goat anti-mouse polyclonal antibody control line which are separated from each other, and is not provided with a transferrin monoclonal antibody detection line.
In this embodiment, the structure of the test strip 253 for detecting helicobacter pylori antigen is the same as that of the test strip 232 for detecting helicobacter pylori antigen in the first embodiment, and will not be described herein again.
In the present embodiment, similarly to the first embodiment, the color particles may each be colloidal gold particles, and accordingly, the third color particle storage pad and the fourth color particle storage pad may each be gold-labeled pads.
In this embodiment, the working principle of the combined detection device for transferrin, hemoglobin and helicobacter pylori antigen according to the present invention is basically the same as that of the first embodiment. That is, when only the control line develops color, the detection result is negative, when the detection line and the control line develop color simultaneously, the detection result is positive, and when neither the detection line nor the control line develops color, the detection failure is indicated.
Through adopting above-mentioned technical scheme, according to the utility model discloses a combined detection device of transferrin, hemoglobin and helicobacter pylori antigen has following advantage at least:
(1) the utility model discloses an among the combined detection device of transferrin, hemoglobin and helicobacter pylori antigen, can detect transferrin, hemoglobin and helicobacter pylori antigen simultaneously through setting up the detection test paper strip subassembly that can detect transferrin, hemoglobin and helicobacter pylori antigen simultaneously.
(2) The utility model discloses an among the combined detection device of transferrin, hemoglobin and helicobacter pylori antigen, through setting up the test paper strip mounting bracket, can conveniently install the test paper strip subassembly.
(3) The utility model discloses an among the combined detection device of transferrin, hemoglobin and helicobacter pylori antigen, will detect the container and fall into two parts on the thickness direction of detecting the container, partly is used for holding the sample container, and another part is used for holding the test paper strip mounting bracket of having installed test paper strip subassembly for whole combined detection device's compact structure, the size is little, and can avoid sample collection portion of holding to damage test paper strip subassembly when inserting in detecting the container effectively.
(4) The utility model discloses an among the combined detection device of transferrin, hemoglobin and helicobacter pylori antigen, the wall portion through making the corresponding test paper strip subassembly of detection container is transparent wall portion, can conveniently observe the testing result.
The above embodiments of the present invention have been described in detail, but it should be added that:
(1) although it is described in the above embodiment that the sealing member is a sealing aluminum foil, the present invention is not limited thereto, and the sealing member may be a sealing plug, a sealing film, or other type of sealing sheet (e.g., a thin plastic sheet).
(2) Although the test strip mounting rack is provided to mount the test strip assembly in the above embodiment, the present invention is not limited thereto, and the test strip assembly may be directly mounted on the inner wall of the test container (for example, a mounting groove may be formed on the inner wall of the test container) without providing the test strip mounting rack.
(3) Although the cross section of the detection container is described as being substantially rectangular in the above embodiments, the present invention is not limited thereto, and the cross section of the detection container may be circular or other shapes.
(4) Although the embodiment described above has explained that the puncture mechanism is provided in the bottom of the detection container, the present invention is not limited to this, and the puncture mechanism may be provided in, for example, an intermediate portion of the detection container.
(5) Although it is described in the above embodiment that the color particles are colloidal gold particles, the present invention is not limited thereto, and the color particles may be colloidal silver particles, colloidal iron particles, magnetic particles, dye particles, latex particles, or fluorescent particles.
Claims (10)
1. A combined detection device for transferrin, hemoglobin and helicobacter pylori antigens is characterized in that the combined detection device comprises a sample collection containing part (1) and a sample detection part (2),
the sample collection containing part (1) is used for collecting and containing a sample to be detected, a sealing element (14) is arranged at the bottom of the sample collection containing part (1),
the sample detection part (2) comprises a detection container (21), detection test strip components (23, 25) and a puncture mechanism (24),
said test strip assembly (23, 25) being disposed within said test receptacle (21) for simultaneously detecting said transferrin, said hemoglobin and said helicobacter pylori antigen,
the piercing mechanism (24) is arranged in the detection container (21),
the sample collection container (1) is insertable into the detection container (21) in the axial direction of the detection container (21), and
when the sample collection container (1) moves towards the puncturing mechanism (24) along the axial direction, the puncturing mechanism (24) can puncture the sealing element (14), so that the sample to be detected in the sample collection container (1) enters the detection container (21), and the sample to be detected can contact the detection test strip assembly.
2. Joint detection device according to claim 1, characterized in that the sample collection containment (1) comprises a collection wand (11) and a sample container (12),
the collection rod (11) is inserted in the sample container (12),
the sealing element (14) is arranged at the bottom of the sample container (12).
3. The joint detection device according to claim 1, wherein the sample detection part (2) further comprises a strip mounting rack (22),
the test strip mounting rack (22) is inserted into the detection container (21), and the detection test strip components (23, 25) are arranged on the test strip mounting rack (22).
4. The joint detection device according to claim 3, wherein the strip mounting bracket (22) is provided with a mounting groove (221), the mounting groove (221) extends along the axial direction,
the test strip components (23, 25) are arranged in the mounting groove (221).
5. Joint detection device according to claim 1, characterised in that said piercing means (24) are arranged at the bottom of said detection container (21).
6. The joint detection device according to claim 1, wherein at least a wall portion of the detection container (21) corresponding to the test strip assembly (23, 25) is a transparent wall portion.
7. The combination detection device according to claim 1, wherein the test strip assembly (23) comprises a transferrin and hemoglobin combination test strip (231) and a helicobacter pylori antigen test strip (232),
the transferrin and hemoglobin combined test strip (231) is used to detect the transferrin and the hemoglobin,
the test strip (232) for detecting helicobacter pylori antigen is used for detecting the helicobacter pylori antigen.
8. The combination detection device of claim 1, wherein the transferrin and hemoglobin combination test strip (231) comprises a first bottom panel (2311), a first absorbent sheet (2312), a first nitrocellulose membrane (2313), a first sample wicking layer (2314), and a first color particle reservoir pad (2315) comprising transferrin mab and hemoglobin mab,
the first nitrocellulose membrane (2313) is loaded with a transferrin monoclonal antibody detection line (23131), a hemoglobin monoclonal antibody detection line (23132) and a goat anti-mouse polyclonal antibody control line (23133) which are separated from each other.
9. The combination detection device of claim 1, wherein the test strip assembly (25) comprises a transferrin test strip (251), a hemoglobin test strip (252), and a helicobacter pylori antigen test strip (253),
the transferrin detection test strip (251) is for detecting the transferrin,
the hemoglobin detection strip (252) is for detecting the hemoglobin,
the helicobacter pylori antigen detection test strip (253) is used for detecting the helicobacter pylori antigen.
10. The combined detection device according to claim 7 or 9, wherein the helicobacter pylori antigen detection test strip (232) comprises a second bottom plate (2321), a second water absorption plate (2322), a second nitrocellulose membrane (2323), a second sample liquid absorption layer (2324), and a second color particle storage pad (2325) containing the helicobacter pylori antigen monoclonal antibody and a biotin-bovine serum albumin conjugate,
the second nitrocellulose membrane (2323) is loaded with a helicobacter pylori antigen monoclonal antibody detection line (23231) and a goat anti-mouse polyclonal antibody and a streptavidin control line (23232) which are separated from each other.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201921185343.4U CN210803493U (en) | 2019-07-25 | 2019-07-25 | Combined detection device for transferrin, hemoglobin and helicobacter pylori antigen |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201921185343.4U CN210803493U (en) | 2019-07-25 | 2019-07-25 | Combined detection device for transferrin, hemoglobin and helicobacter pylori antigen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN210803493U true CN210803493U (en) | 2020-06-19 |
Family
ID=71231351
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201921185343.4U Active CN210803493U (en) | 2019-07-25 | 2019-07-25 | Combined detection device for transferrin, hemoglobin and helicobacter pylori antigen |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN210803493U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110275018A (en) * | 2019-07-25 | 2019-09-24 | 万华普曼生物工程有限公司 | The joint-detection device of transferrins, hemoglobin and Heliobacter pylori antigen |
-
2019
- 2019-07-25 CN CN201921185343.4U patent/CN210803493U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110275018A (en) * | 2019-07-25 | 2019-09-24 | 万华普曼生物工程有限公司 | The joint-detection device of transferrins, hemoglobin and Heliobacter pylori antigen |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US6548019B1 (en) | Device and methods for single step collection and assaying of biological fluids | |
| US7780915B2 (en) | Fecal sample test device and methods of use | |
| CN1168985C (en) | Immunochromatographic assay devices with separators | |
| EP3302266B1 (en) | Devices, systems and methods for in-vivo immunoassay | |
| EP0815424B1 (en) | Sample collection device | |
| NZ575068A (en) | Analysis device for determining the presence of an analyte comprising a test strip having a separable second reagent zone. | |
| MX2007011116A (en) | Dual path immunoassay device. | |
| EP2689729A1 (en) | Disposable test device | |
| US20110201131A1 (en) | Antibody detection method involving oligonucleotide enhanced colloidal gold signal | |
| CN210803493U (en) | Combined detection device for transferrin, hemoglobin and helicobacter pylori antigen | |
| CN212622625U (en) | Bivalent antibody quick-detection reagent box | |
| WO2021012469A1 (en) | Device for combined testing of transferrin, hemoglobin, and helicobacter pylori antigen | |
| EP2049903A2 (en) | An immunochromatography device for the diagnosis of diseases in a sample | |
| US8623291B2 (en) | Multiple analyte assay device | |
| CN211043408U (en) | Combined detection device for transferrin, hemoglobin and helicobacter pylori antigen | |
| CN211505565U (en) | Quantum dot-labeled rapid immunochromatographic test strip for detecting type I Shiga toxin | |
| CN206074619U (en) | One kind is occulted blood quick diagnosis chromatographic test paper | |
| JP2619018B2 (en) | Pre-packaged disposable device for performing immunoassays | |
| US7863053B2 (en) | Swab-based diagnostic systems | |
| JP2017509889A (en) | Lateral flow test and related improvements | |
| US20100068726A1 (en) | Antigen detection method involving an oligonucleotide enhanced colloidal gold signal | |
| CN214278193U (en) | Detection kit structure for stool detection | |
| CN202101994U (en) | Blood testing immunochromatographic box | |
| CN211669209U (en) | Hepatitis B detection module device | |
| CN213633461U (en) | Test paper for simultaneously detecting alcohol and drugs in liquid sample |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant |