CN210775223U - Multichannel quantum dot fluorescence imager - Google Patents
Multichannel quantum dot fluorescence imager Download PDFInfo
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- CN210775223U CN210775223U CN201921794192.2U CN201921794192U CN210775223U CN 210775223 U CN210775223 U CN 210775223U CN 201921794192 U CN201921794192 U CN 201921794192U CN 210775223 U CN210775223 U CN 210775223U
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- 239000002096 quantum dot Substances 0.000 title claims abstract description 46
- 238000012360 testing method Methods 0.000 claims abstract description 72
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- 238000009434 installation Methods 0.000 claims description 3
- 238000002474 experimental method Methods 0.000 abstract description 4
- 238000002073 fluorescence micrograph Methods 0.000 abstract description 2
- 230000003760 hair shine Effects 0.000 abstract description 2
- 238000007689 inspection Methods 0.000 abstract description 2
- 238000011160 research Methods 0.000 abstract description 2
- 230000000694 effects Effects 0.000 description 10
- 238000010586 diagram Methods 0.000 description 4
- 238000005259 measurement Methods 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 230000001174 ascending effect Effects 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
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- WHXSMMKQMYFTQS-UHFFFAOYSA-N Lithium Chemical compound [Li] WHXSMMKQMYFTQS-UHFFFAOYSA-N 0.000 description 1
- 239000012491 analyte Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000002059 diagnostic imaging Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 230000017525 heat dissipation Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 229910052744 lithium Inorganic materials 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 239000004065 semiconductor Substances 0.000 description 1
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Abstract
The utility model provides a multichannel quantum dot fluorescence imager relates to biological science research and medical science inspection application technical field. The multi-channel quantum dot fluorescence imager comprises a shell, and a rotating seat, an ultraviolet light source, a camera and an optical filter which are positioned in the shell; the rotary seat is arranged in the shell and used for placing and rotating the test paper rotary cylinder; the camera and the ultraviolet light source are both positioned on the outer side of the circumferential direction of the test paper rotating cylinder, and are arranged at intervals along the axial direction of the test paper rotating cylinder; an optical filter is arranged between the camera and the test paper rotating cylinder. The utility model discloses a multichannel quantum dot fluorescence imager when utilizing a plurality of test paper strips of rotatable placing of roating seat, obtains through the reasonable setting of ultraviolet source, camera and light filter that the test paper strip receives ultraviolet ray and shines the fluorescence image information that produces, can truly reflect the experimental data after the back for the analysis, has increased substantially the efficiency and the rate of accuracy of experiment.
Description
Technical Field
The utility model relates to a technical field is used in biological science research and medical science inspection, particularly, relates to a multichannel quantum dot fluorescence imager.
Background
In medical imaging technology, quantum dots serving as semiconductor nano luminescent materials provide great convenience for rapid determination of various analytes.
In the existing quantum dot measurement equipment and method, an ultraviolet light source is usually arranged between a camera and a test strip, and the test strip to be measured is placed in the irradiation range of the ultraviolet light source. Although the equipment and the method avoid a structure using prism refraction, reduce the installation space of detection equipment, easily cause light interference between a camera and an ultraviolet light source, and simultaneously are difficult to reasonably set an optical filter for filtering fluorescence.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to provide a multichannel quantum dot fluorescence imager, it can rationally set up the light filter in order to reduce light interference and improve the accuracy of survey, and place a plurality of test paper strips in a flexible way and realize once only survey one by one to a plurality of test paper strips, improve experimental efficiency.
The embodiment of the utility model is realized like this:
a multi-channel quantum dot fluorescence imager comprises a shell, and a rotating seat, an ultraviolet light source, a camera and an optical filter which are positioned in the shell; the rotary seat is arranged in the shell and used for placing and rotating the test paper rotary cylinder; the camera and the ultraviolet light source are both positioned on the outer side of the circumferential direction of the test paper rotating cylinder, and are arranged at intervals along the axial direction of the test paper rotating cylinder; the optical filter is arranged between the camera and the test paper rotating cylinder.
By adopting the multi-channel quantum dot fluorescence imager, a plurality of test strips can be placed in front of the ultraviolet light source and the camera in a one-to-one correspondence manner on the test paper rotary drum, and all the test strips are measured one by one at a time by rotating the rotary seat, so that the experimental efficiency is improved. In addition, the camera and the ultraviolet light source are arranged on the outer side of the circumferential direction of the test paper rotating cylinder and are arranged at intervals along the axis direction of the test paper rotating cylinder, so that an optical filter is favorably arranged between the camera and the test paper, the phenomenon that the optical filter blocks emergent rays is avoided, multiple times of invalid refraction of the optical filter on the emergent rays and incident rays is reduced, and the experiment accuracy is improved.
In a preferred embodiment of the present invention, the ultraviolet light source is hinged to the housing, and a hinge shaft of the ultraviolet light source is perpendicular to an axis of the test paper rotating cylinder; the ultraviolet light source can change a mounting angle with respect to the housing around the hinge shaft. The technical effects are as follows: the T line position and the C line position of each test strip are different, and the signal intensity displayed by the T line and the signal intensity displayed by the C line are different when different test samples are measured. And the installation angle of the ultraviolet light source is changed, the irradiation angle of emergent light of the ultraviolet light source can be adjusted, and the T line and the C line on the test strip can be accurately corresponding to meet the measurement requirements of different test strips and different samples to be measured.
In the preferred embodiment of the present invention, the camera is movably disposed on the housing, and the camera can move along the axis of the test paper rotating cylinder. The technical effects are as follows: in consideration that the different test strips have different T-line positions and C-line positions, the camera can move along the axis direction of the test strip rotating cylinder, the height position of the camera for acquiring the fluorescent signal can be changed, and the measurement requirements of different test strips and different samples to be measured are met.
In a preferred embodiment of the present invention, the camera is mounted in the housing through a pillar; the length direction of the upright column is parallel to the axial direction of the test paper rotating cylinder, a guide groove is formed in the upright column, and a guide pin is arranged on the camera corresponding to the guide groove. The technical effects are as follows: the guide slot and the guide pin structure provide a mechanism for stepless adjustment of the upper position and the lower position of the camera on the stand column, so that the camera can move in the length direction of the guide slot and accurately corresponds to the T line position and the C line position on the test strip. The guide pin can preferably adopt a spring shaft pin to quickly adjust the ascending and descending of the camera. The camera may be attached to the column through a screw hole, and may be fixed to the upper side or the lower side of the column in the same manner.
In the preferred embodiment of the present invention, the test paper rotating drum is further included; the test paper rotating cylinder is installed on the rotating seat. The technical effects are as follows: a plurality of test strips are placed on one test strip rotating cylinder, and each time the test strip rotates by one angle, a certain test strip is required to accurately correspond to the ultraviolet light source and the camera.
In the preferred embodiment of the present invention, the utility model further comprises a reset device; the resetting device is arranged at the bottom of the rotating seat. The technical effects are as follows: after all the test paper strips in one test paper rotary cylinder are tested, the rotary seat can be restored to the initial position through the resetting device, and the initial position of the next test paper rotary cylinder can be conveniently determined.
In a preferred embodiment of the present invention, the system further comprises a processor; the processor is arranged in the shell and is respectively and electrically connected with the camera and the ultraviolet light source. The technical effects are as follows: the processor is used for controlling the emergent light of the ultraviolet light source and processing and analyzing the fluorescence signal collected by the camera.
In a preferred embodiment of the present invention, the device further comprises a battery; the battery is arranged in the shell and is electrically connected with the rotating seat, the ultraviolet light source, the camera and the processor. The technical effects are as follows: the battery can independently provide power for the rotating seat, the ultraviolet light source, the camera and the processor, and the portability of the equipment is improved.
In a preferred embodiment of the present invention, the device further comprises a display screen; the display screen is arranged on the outer side of the shell and is electrically connected with the processor. The technical effects are as follows: the processor analyzes and processes the fluorescence emitted by the test strip and then directly displays the fluorescence through the display screen, so that a user can read the test result quickly.
In a preferred embodiment of the present invention, the device further comprises a printer; the printer is arranged in the shell and is electrically connected with the processor and the display screen. The technical effects are as follows: the printer can output the analysis result of the processor in real time, and is convenient for storing and sorting the experimental data.
The embodiment of the utility model provides a beneficial effect is:
the utility model discloses a multichannel quantum dot fluorescence imager when utilizing a plurality of test paper strips of rotatable placing of roating seat, obtains through the reasonable setting of ultraviolet source, camera and light filter that the test paper strip receives ultraviolet ray and shines the fluorescence image information that produces, can truly reflect the experimental data after the back for the analysis, has increased substantially the efficiency and the rate of accuracy of experiment.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings that are required to be used in the embodiments will be briefly described below, it should be understood that the following drawings only illustrate some embodiments of the present invention, and therefore should not be considered as limiting the scope, and for those skilled in the art, other related drawings can be obtained according to the drawings without inventive efforts.
Fig. 1 is a schematic diagram of an external structure of a multi-channel quantum dot fluorescence imager according to a first embodiment of the present invention;
fig. 2 is a schematic view illustrating a first view angle of an internal structure of a multi-channel quantum dot fluorescence imager according to a first embodiment of the present invention;
fig. 3 is a schematic view of a second view angle of the internal structure of the multi-channel quantum dot fluorescence imager according to the first embodiment of the present invention;
fig. 4 is a schematic diagram of an external structure of a multi-channel quantum dot fluorescence imager according to a fourth embodiment of the present invention;
fig. 5 is a schematic view of a first viewing angle of an internal structure of a multi-channel quantum dot fluorescence imager according to a fourth embodiment of the present invention;
fig. 6 is a schematic view of a second view angle of an internal structure of a multi-channel quantum dot fluorescence imager according to a fourth embodiment of the present invention.
In the figure: 1-a shell; 2-a rotating seat; 3-a source of ultraviolet light; 4-a camera; 5-an optical filter; 6-upright post; 7-test paper rotating cylinder; 8-a resetting device; 9-a processor; 10-a battery; 11-a display screen; 12-printer.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, but not all, embodiments of the present invention. The components of the embodiments of the present invention, as generally described and illustrated in the figures herein, can be arranged and designed in a wide variety of different configurations.
Thus, the following detailed description of the embodiments of the present invention, presented in the accompanying drawings, is not intended to limit the scope of the invention, as claimed, but is merely representative of selected embodiments of the invention. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative efforts belong to the protection scope of the present invention.
It should be noted that: like reference numbers and letters refer to like items in the following figures, and thus, once an item is defined in one figure, it need not be further defined and explained in subsequent figures.
In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", and the like indicate the position or positional relationship based on the position or positional relationship shown in the drawings, or the position or positional relationship which is usually placed when the product of the present invention is used, and are only for convenience of description and simplification of the description, but do not indicate or imply that the device or element referred to must have a specific position, be constructed and operated in a specific orientation, and thus, should not be construed as limiting the present invention. Furthermore, the terms "first," "second," "third," and the like are used solely to distinguish one from another and are not to be construed as indicating or implying relative importance.
Furthermore, the terms "horizontal", "vertical", "overhang" and the like do not imply that the components are required to be absolutely horizontal or overhang, but may be slightly inclined. For example, "horizontal" merely means that the direction is more horizontal than "vertical" and does not mean that the structure must be perfectly horizontal, but may be slightly inclined.
In the description of the present invention, it should also be noted that, unless otherwise explicitly specified or limited, the terms "disposed," "mounted," "connected," and "connected" are to be construed broadly, e.g., as meaning either a fixed connection, a removable connection, or an integral connection; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood in specific cases to those skilled in the art.
Some embodiments of the present invention will be described in detail below with reference to the accompanying drawings. The embodiments described below and the features of the embodiments can be combined with each other without conflict.
The first embodiment:
fig. 1 is a schematic diagram of an external structure of a multi-channel quantum dot fluorescence imager according to a first embodiment of the present invention; fig. 2 is a schematic view illustrating a first view angle of an internal structure of a multi-channel quantum dot fluorescence imager according to a first embodiment of the present invention; fig. 3 is a schematic view of a second view angle of the internal structure of the multi-channel quantum dot fluorescence imager according to the first embodiment of the present invention.
Referring to fig. 1 to 3, the present embodiment provides a multi-channel quantum dot fluorescence imager, which includes a housing 1, and a rotating base 2, an ultraviolet light source 3, a camera 4, and an optical filter 5 located in the housing 1; the rotary seat 2 is arranged in the shell 1 and used for placing and rotating the test paper rotary cylinder 7; the camera 4 and the ultraviolet light source 3 are both positioned on the circumferential outer side of the test paper rotating cylinder 7, and the camera 4 and the ultraviolet light source 3 are arranged at intervals along the axial direction of the test paper rotating cylinder 7; an optical filter 5 is arranged between the camera 4 and the test paper rotating cylinder 7.
The working principle of the multi-channel quantum dot fluorescence imager is as follows: the ultraviolet light source 3 emits light to the test strip, a sample to be detected on the test strip emits fluorescence under the irradiation of ultraviolet light, the fluorescence enters the camera 4 after being filtered by the optical filter 5, and the detected analyte in the sample to be detected can be rapidly detected through analysis after the fluorescence is captured by the camera 4. Utilize above-mentioned multichannel quantum dot fluorescence imager, can place a plurality of test paper strips in the place ahead of ultraviolet source 3 and camera 4 on test paper revolving drum 7 one-to-one, through rotating roating seat 2, once only survey whole test paper strips one by one, improved the experimental efficiency of equipment. In addition, because camera 4 and ultraviolet source 3 install in the circumference outside of test paper rotary drum 7 and along the axis direction interval setting of test paper rotary drum 7, do benefit to and set up light filter 5 between camera 4 and test paper strip, avoid light filter 5 to the separation of emergent ray also to reduce the many times invalid refraction of light filter 5 to emergent ray and incident ray, improved the experiment accuracy.
Second embodiment:
the present embodiment provides a multi-channel quantum dot fluorescence imager, which is substantially the same as the multi-channel quantum dot fluorescence imager of the first embodiment, and the difference between the two embodiments is that an ultraviolet light source 3 in the multi-channel quantum dot fluorescence imager of the present embodiment is hinged to a housing 1, and a hinge shaft of the ultraviolet light source is perpendicular to an axis of a test paper rotating cylinder 7; the ultraviolet light source 3 can change a mounting angle with respect to the housing 1 about the hinge shaft.
The ultraviolet light source 3 is hinged on the shell 1 and then fixed through a shaft pin, or the ultraviolet light source 3 directly realizes the adjustment of a deflection angle through a meshed gear.
In addition, the ultraviolet light source 3 can also be fixedly installed in the housing 1 to ensure the constancy of the emergent ray angle.
The third embodiment:
the present embodiment provides a multi-channel quantum dot fluorescence imager, which is substantially the same as the multi-channel quantum dot fluorescence imagers of the first and second embodiments, and the difference between the multi-channel quantum dot fluorescence imager of the present embodiment is that a camera 4 is movably disposed in a housing 1, and the camera 4 can move along the axial direction of a test paper rotating cylinder 7.
Wherein, the camera 4 is arranged in the shell 1 through the upright post 6; the length direction of the upright post 6 is parallel to the axial direction of the test paper rotating cylinder 7, the upright post 6 is provided with a guide groove, the length direction of the guide groove is parallel to the axial direction of the test paper rotating cylinder 7, and the camera 4 is provided with a guide pin corresponding to the guide groove.
The guide pin is preferably a spring pin to quickly adjust the ascending and descending of the camera 4.
The camera 4 may be attached to the column 6 by screw holes, and may be fixed to the upper side or the lower side of the column 6 in the same manner.
The fourth embodiment:
fig. 4 is a schematic diagram of an external structure of a multi-channel quantum dot fluorescence imager according to a fourth embodiment of the present invention; fig. 5 is a schematic view of a first viewing angle of an internal structure of a multi-channel quantum dot fluorescence imager according to a fourth embodiment of the present invention; fig. 6 is a schematic view of a second view angle of an internal structure of a multi-channel quantum dot fluorescence imager according to a fourth embodiment of the present invention. Referring to fig. 4, 5 and 6, the present embodiment provides a multi-channel quantum dot fluorescence imager, which is substantially the same as the multi-channel quantum dot fluorescence imagers of the first, second and third embodiments, and the difference between the multi-channel quantum dot fluorescence imager of the present embodiment further includes a test paper rotating cylinder 7; the test paper rotary cylinder 7 is arranged on the rotary seat 2.
In addition, on the basis of any of the above embodiments, as shown in fig. 2, 3, 5 and 6, the device further comprises a resetting device 8; the resetting device 8 is arranged at the bottom of the rotating base 2.
On the basis of any of the above embodiments, as shown in fig. 2, 3, 5 and 6, the system further comprises a processor 9; the processor 9 is arranged in the shell 1, and the processor 9 is respectively electrically connected with the camera 4 and the ultraviolet light source 3. The processor 9 can be installed by a vertical plate erected in the housing 1, wherein the vertical plate is provided with air holes to improve the heat dissipation effect of the processor 9.
On the basis of any of the above embodiments, as shown in fig. 2, 3, 5 and 6, the battery pack further comprises a battery 10; the battery 10 is disposed in the housing 1 and is electrically connected to the rotary base 2, the ultraviolet light source 3, the camera 4, and the processor 9. Preferably, the battery 10 should be a rechargeable lithium battery 10 to meet the portability requirements of the device.
Further, as shown in fig. 1 and fig. 2, the display device further includes a display screen 11; the display screen 11 is disposed outside the housing 1 and is electrically connected to the processor 9. Preferably, the display screen 11 is arranged at the outer side of the top of the shell 1, so that the observation is convenient. Moreover, the display screen 11 is preferably a touch display screen 11, so as to be convenient for a user to operate manually.
Further, as shown in fig. 2, 3, 5, and 6, a printer 12 is further included; the printer 12 is built into the housing 1 and is electrically connected to the processor 9 and the display screen 11.
The above is only a preferred embodiment of the present invention, and is not intended to limit the present invention, and various modifications and changes will occur to those skilled in the art. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (10)
1. A multi-channel quantum dot fluorescence imager is characterized by comprising a shell (1), a rotating seat (2), an ultraviolet light source (3), a camera (4) and an optical filter (5), wherein the rotating seat (2), the ultraviolet light source (3), the camera (4) and the optical filter (5) are positioned in the shell (1);
the rotary seat (2) is arranged in the shell (1) and used for placing and rotating the test paper rotary cylinder (7);
the camera (4) and the ultraviolet light source (3) are both positioned on the outer side of the test paper rotating cylinder (7) in the circumferential direction, and the camera (4) and the ultraviolet light source (3) are arranged at intervals along the axial direction of the test paper rotating cylinder (7);
the optical filter (5) is arranged between the camera (4) and the test paper rotating cylinder (7).
2. The multi-channel quantum dot fluorescence imager according to claim 1, characterized in that the ultraviolet light source (3) is hinged to the housing (1) with a hinge axis perpendicular to the axis of the test paper rotating cylinder (7); the ultraviolet light source (3) can change the installation angle relative to the shell (1) around the hinge shaft.
3. The multi-channel quantum dot fluorescence imager of claim 1, wherein the camera (4) is movably arranged on the housing (1), and the camera (4) can move along the axial direction of the test paper rotating cylinder (7).
4. The multi-channel quantum dot fluorescence imager of claim 3, characterized in that the camera (4) is mounted inside the housing (1) by a post (6); the length direction of the upright post (6) is parallel to the axial direction of the test paper rotating cylinder (7), the upright post (6) is provided with a guide groove, and the camera (4) is provided with a guide pin corresponding to the guide groove.
5. The multi-channel quantum dot fluorescence imager of claim 1, further comprising a test paper rotating drum (7); the test paper rotating cylinder (7) is arranged on the rotating seat (2).
6. The multi-channel quantum dot fluorescence imager of claim 1, further comprising a reset device (8); the resetting device (8) is arranged at the bottom of the rotating seat (2).
7. The multi-channel quantum dot fluorescence imager of claim 1, further comprising a processor (9); the processor (9) is arranged in the shell (1), and the processor (9) is electrically connected with the camera (4) and the ultraviolet light source (3) respectively.
8. The multi-channel quantum dot fluorescence imager of claim 7, further comprising a battery (10); the battery (10) is arranged in the shell (1) and is electrically connected with the rotating seat (2), the ultraviolet light source (3), the camera (4) and the processor (9).
9. The multi-channel quantum dot fluorescence imager of claim 7, further comprising a display screen (11); the display screen (11) is arranged on the outer side of the shell (1) and is electrically connected with the processor (9).
10. The multi-channel quantum dot fluorescence imager of claim 9, further comprising a printer (12); the printer (12) is arranged in the shell (1) and is electrically connected with the processor (9) and the display screen (11).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201921794192.2U CN210775223U (en) | 2019-10-22 | 2019-10-22 | Multichannel quantum dot fluorescence imager |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201921794192.2U CN210775223U (en) | 2019-10-22 | 2019-10-22 | Multichannel quantum dot fluorescence imager |
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| Publication Number | Publication Date |
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| CN210775223U true CN210775223U (en) | 2020-06-16 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201921794192.2U Active CN210775223U (en) | 2019-10-22 | 2019-10-22 | Multichannel quantum dot fluorescence imager |
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| CN (1) | CN210775223U (en) |
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Inventor after: Wang Shengqi Inventor after: Xiao Rui Inventor after: Rong Zhen Inventor after: Dong Jian Inventor after: Sun Meijie Inventor before: Wang Shengqi Inventor before: Xiao Rui Inventor before: Wang Dongfeng Inventor before: Rong Zhen Inventor before: Dong Jian Inventor before: Wang Feng Inventor before: Sun Meijie |
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| CB03 | Change of inventor or designer information |