CN210690596U - Immunofluorescence anti-drop cleaner - Google Patents

Abstract

The utility model relates to an anticreep purger technical field, specific immunofluorescence anticreep purger that says so, including control box and the washing tank that sets up rather than the intercommunication, the integral setting of control box is in the washing tank top that holds PBS liquid, the sleeve is all installed through the bolt to the control box inner wall left and right sides, the loop bar has been cup jointed to the sleeve inside, the loop bar outer wall is stained with the anti-skidding rubber cover of hugging closely at the sleeve inner wall, the sleeve outer wall is close to the equal threaded connection of open end and stretches into its inside and support tightly the locking bolt at the loop bar outer wall, the utility model aims at providing an immunofluorescence anticreep purger, can guarantee the tissue and do not take off the piece, can portably wash again, the control flow rate, labour saving and time saving improves the quality of kidney biopsy.

Description

Immunofluorescence anti-drop cleaner

Technical Field

The utility model relates to an anticreep purger technical field, specific immunofluorescence anticreep purger that says so.

Background

In recent years, the prevalence rate of Chronic Kidney Disease (CKD) is high and tends to increase year by year, and the pathological examination of renal biopsy is an important means for diagnosis, treatment guidance and prognosis of renal diseases. Immunofluorescence is an essential important pathological technology, can clarify pathological changes and pathological types of kidney diseases, can make final diagnosis of the diseases by combining clinical manifestations and inspection indexes, can make treatment schemes and judge prognosis of patients according to the pathological changes, the pathological types and the severity of pathological changes, and can research etiology and pathogenesis of the kidney diseases through renal biopsy pathological examination to discover new kidney diseases and enrich kidney pathology.

However, quality assurance of pathological preparations of kidney biopsies is not left to the successful implementation of each link. In the immunofluorescence slide preparation process, in order to prevent the antibody reagent residues caused by non-specific staining, appropriate cleaning method (time and frequency) is especially important. In the current practical work, PBS is used for washing for five minutes times three times, the washing flow rate is difficult to control the standard, non-specific dyeing is easy to cause due to insufficient washing, and the phenomenon of chip removal is easy to occur due to excessive washing. Therefore, the designed simple, convenient and practical immunofluorescence anti-drop cleaner can ensure that tissues do not drop, can be cleaned simply and conveniently, controls the flow rate, saves time and labor, and has very important significance for improving the quality of kidney biopsy pathological section.

SUMMERY OF THE UTILITY MODEL

In order to make up for the above deficiency, the utility model provides an immunofluorescence anti-drop cleaner, which aims to solve the problems in the background technology.

The technical scheme of the utility model is that: an immunofluorescence anti-falling cleaner comprises an operation box and a cleaning tank communicated with the operation box, wherein the operation box is integrally arranged above the cleaning tank containing PBS liquid, sleeves are mounted on the left side and the right side of the inner wall of the operation box through bolts, a loop bar is sleeved inside the sleeves, an anti-skidding rubber sleeve tightly attached to the inner wall of the sleeves is adhered to the outer wall of the loop bar, locking bolts extending into the sleeve and tightly abutting against the outer wall of the loop bar are connected to the outer wall of the sleeves through threads close to an opening end, U-shaped clamping rods are welded to the tail end portions of the loop bar, L-shaped abutting rods are welded to the bottoms of the opposite sides of the two U-shaped abutting rods, guide sleeves are welded to vertical rods at two ends of the U-shaped abutting rods, guide rods are tightly sleeved on the inner walls of the guide sleeves, springs are welded between the inner ends of the guide rods and the inner bottoms of the guide sleeves, a glass slide body is placed between the, draw liquid pipeline terminal portion and communicate in the control box and set up towards slide glass body upper portion, be located the control box and the washing tank outside install circulating pump and flow control valve on the drawing liquid pipeline respectively, the circulating pump model is ISG, and the flow control valve model is DN15-150, is located the control box inside draw liquid pipeline rear slope downward screw thread intercommunication in pairs has the gondola water faucet.

Preferably, the bottom slope sets up and has banding opening to the rear below in the control box, just the integral baffle that is equipped with of washing tank inner wall rear side, the baffle sets up with control box upper portion intercommunication, the control box front portion still articulates through the hinge has transparent chamber door, the rear end portion week side of transparent chamber door is laminated mutually with the front portion of control box.

The liquid which is washed by the redundant antibodies of the glass slide body can be conveniently infiltrated into the back of the washing groove through the liquid leakage hole, and the water with the antibodies can be discharged by virtue of the liquid discharge pipeline at the bottom of the back of the right side of the washing groove.

Preferably, the bottom end of the guide rod is smooth and semi-spherical, the lowest end of the guide rod is in contact with the upper end face of the glass slide body, the left side and the right side of the glass slide body are in contact with vertical rods at two ends of the U-shaped clamping rod, and the cross sections of the upper section of the U-shaped clamping rod and the upper section of the L-shaped abutting rod are circular.

This setting is the upper segment of circular shape U-shaped clamping bar upper segment and L shape through the cross section and supports the upper segment of tight pole and can press from both sides the slide glass body with the help of the guide arm that the bottom is smooth hemisphere form and press from both sides tightly fixedly to do not hinder the gondola water faucet again and wash the effect, reduce choked flow's condition and take place, need explain simultaneously that the long length of level of U-shaped clamping bar bottom is less than the length of slide glass body.

Preferably, washing tank upper portion left side front side intercommunication has the inlet channel, both sides all communicate liquid discharge tube around washing tank right side wall bottom, still install the gate valve on the liquid discharge tube.

This setting is convenient for draw the PBS liquid to the control box inside through liquid inlet pipe and external drawing liquid pump mutually supporting.

Compared with the prior art, the beneficial effect of this application:

the utility model aims at providing an immunofluorescence anticreep purger can guarantee that the tissue does not take off the piece, can portably wash again, and the control flow rate, labour saving and time saving improves the quality of kidney biopsy pathology film-making. The utility model discloses simple structure, convenient to use has very good practicality and popularization and application and worth.

Drawings

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings needed to be used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without inventive exercise.

Fig. 1 is a schematic front view of the transparent box door of the present invention after being opened;

FIG. 2 is a schematic view of the position relationship between the U-shaped clamping bar, the guide bar and the L-shaped tightening bar of the present invention;

FIG. 3 is a schematic view of the connection relationship between the guide sleeve and the guide rod of the present invention;

FIG. 4 is a schematic view of the connection between the sleeve and the loop bar according to the present invention;

fig. 5 is a schematic view of the connection relationship between the bottom wall of the operation box and the cleaning tank of the present invention.

Wherein the reference numerals are summarized as follows: 1. an operation box; 2. a cleaning tank; 3. a sleeve; 4. a loop bar; 5. an anti-slip rubber sleeve; 6. locking the bolt; 7. a U-shaped clamping bar; 8. an L-shaped abutment bar; 9. a guide sleeve; 10. a guide bar; 11. a spring; 12. a slide body; 13. a liquid extraction pipeline; 14. a circulation pump; 15. a flow control valve; 16. a shower head; 17. a partition plate; 18. a transparent box door; 19. a liquid inlet pipeline; 20. a liquid discharge pipeline.

Detailed Description

The invention is further described with reference to the following figures and specific embodiments.

Referring to fig. 1-5, the utility model relates to an immunofluorescence anti-drop cleaner, which comprises an operation box 1 and a cleaning tank 2 communicated with the operation box 1, wherein the operation box 1 is integrally arranged above the cleaning tank 2 containing PBS liquid, sleeves 3 are arranged on the left and right sides of the inner wall of the operation box 1 through bolts, a loop bar 4 is sleeved in the sleeves 3, an anti-slip rubber sleeve 5 tightly attached to the inner wall of the sleeve 3 is adhered on the outer wall of the loop bar 4, a locking bolt 6 extending into the sleeve 3 and tightly abutting against the outer wall of the loop bar 4 is connected with the outer wall of the sleeve 3 close to an opening end through threads, U-shaped abutting bars 7 are welded at the tail end parts of the loop bar 4, L-shaped abutting bars 8 are welded at the bottoms of the opposite sides of the two U-shaped abutting bars 7, guide sleeves 9 are welded on the vertical bars at the two ends of the U-shaped abutting bars 7, guide bars 10 are tightly sleeved on the inner walls of the guide sleeves, l shape is supported and is placed slide glass body 12 between pole 8 and guide arm 10, 2 bottom intercommunications of washing tank have drawing liquid pipeline 13, drawing liquid pipeline 13 tip intercommunication in control box 1 and towards slide glass body 12 upper portion setting, be located control box 1 and 2 outsides of washing tank install circulating pump 14 and flow control valve 15 on the drawing liquid pipeline 13 respectively, be located the 1 inside of control box 13 slope downward screw thread intercommunication in pairs in drawing liquid pipeline 13 rear has gondola water faucet 16. Bottom slope sets up and has banding opening to the rear below in operation box 1, just the integral baffle 17 that is equipped with of 2 inner wall rear sides of washing tank, baffle 17 sets up with 1 upper portion intercommunication of operation box, 1 front portion of operation box still articulates through the hinge has transparent chamber door 18, the rear end portion week side of transparent chamber door 18 is laminated mutually with the front portion of operation box 1. The bottom end of the guide rod 10 is smooth and semi-spherical, the lowest end of the guide rod is in contact with the upper end face of the glass slide body 12, the left side and the right side of the glass slide body 12 are in contact with vertical rods at two ends of the U-shaped clamping rod 7, and the cross sections of the upper section of the U-shaped clamping rod 7 and the upper section of the L-shaped abutting rod 8 are circular. Washing tank 2 upper portion left side front side intercommunication has inlet channel 19, both sides all communicate liquid discharge tube 20 around washing tank 2 right side wall bottom, still install the gate valve on the liquid discharge tube 20.

The electrical components presented in the document are all electrically connected with an external master controller and 220V mains, and the master controller can be a conventional known device controlled by a computer or the like.

In order to better understand the utility model by those skilled in the art, the working process of the utility model is briefly described with reference to the attached drawings: the application can adjust the sleeving distance between the sleeve 3 and the inner loop bar 4 by means of the locking bolt 6 in threaded connection with the sleeve 3, can increase the stability of sleeving and fixing the sleeve 3 and the loop bar 4 by means of the anti-slip rubber sleeve 5, can tightly support the left side and the right side of the glass slide body 12 by means of the two U-shaped clamping rods 7, can play a role of lifting and supporting the glass slide body 12 by means of the L-shaped clamping rod 8, can control the guide rod 10 with a smooth semi-spherical bottom end to press the upper part of the glass slide body 12 by means of the tension force of the spring 11, thereby ensuring the occurrence of the strip-off condition in the subsequent washing process, can clamp the glass slide bodies 12 with different sizes by means of the arrangement, can stand for a period of time after dripping the fluorescent reagent by means of the antibody in the operation box 1, and then can pump the liquid at the front part in the cleaning tank 2 to the front part in the operation box 1 by, the redundant antibodies on the glass slide body 12 can be washed by the shower heads 16 which are obliquely and downwards communicated in pairs behind the liquid pumping pipeline 13, the washing force can be controlled by the flow control valve 15, the washed solution with the fluorescent reagent can flow backwards to the rear of the washing tank 2 along the bottom in the operation box 1, then the water with the antibodies is discharged by the liquid discharge pipeline 20 at the bottom of the rear right side of the washing tank 2, and the washing operation is carried out by circulating the water to all the glass slide bodies 12.

The basic principles, main features and advantages of the present invention have been shown and described above. It will be understood by those skilled in the art that the present invention is not limited to the above embodiments, and that the foregoing embodiments and descriptions are provided only to illustrate the principles of the present invention without departing from the spirit and scope of the present invention. The scope of the invention is defined by the appended claims and equivalents thereof.

Claims (4)

1. The utility model provides an immunofluorescence anticreep purger, includes control box (1) and washing tank (2) rather than the intercommunication setting, its characterized in that: the operation box (1) is integrally arranged above a cleaning tank (2) containing PBS liquid, sleeves (3) are mounted on the left side and the right side of the inner wall of the operation box (1) through bolts, sleeve rods (4) are sleeved inside the sleeves (3), anti-skid rubber sleeves (5) tightly attached to the inner wall of the sleeves (3) are adhered to the outer wall of the sleeve rods (4), the outer wall of each sleeve (3) is close to an opening end and is connected with a locking bolt (6) stretching into the sleeve rod (4) and tightly supporting the outer wall of the sleeve rod in a threaded manner, U-shaped clamping rods (7) are welded at the tail end parts of the sleeve rods (4), L-shaped abutting rods (8) are welded at the bottoms of the opposite sides of the U-shaped clamping rods (7), guide sleeves (9) are welded on vertical rods at the two ends of the U-shaped clamping rods (7), guide rods (10) are tightly sleeved on the inner wall of the guide sleeves (9), springs (11) are welded between the inner ends of, l shape supports places between tight pole (8) and guide arm (10) and has slide glass body (12), washing tank (2) bottom intercommunication has drawing liquid pipeline (13), drawing liquid pipeline (13) terminal portion intercommunication in control box (1) and towards slide glass body (12) upper portion setting, is located control box (1) and washing tank (2) outside draw and install circulating pump (14) and flow control valve (15) on liquid pipeline (13) respectively, be located control box (1) inside draw liquid pipeline (13) rear slope downward screw intercommunication in pairs has gondola water faucet (16).

2. The immunofluorescence anti-detachment washer according to claim 1, wherein: bottom slope sets up and has banding opening to the rear below in control box (1), just washing tank (2) inner wall rear side is integral to be equipped with baffle (17), baffle (17) and control box (1) upper portion intercommunication set up, control box (1) front portion still articulates through the hinge has transparent chamber door (18), the rear end portion week side of transparent chamber door (18) is laminated mutually with the front portion of control box (1).

3. The immunofluorescence anti-detachment washer according to claim 1, wherein: the slide glass is characterized in that the bottom end of the guide rod (10) is smooth and semi-spherical, the lowest end of the guide rod is in contact with the upper end face of the slide glass body (12), the left side and the right side of the slide glass body (12) are in contact with the vertical rods at the two ends of the U-shaped clamping rod (7), and the cross sections of the upper section of the U-shaped clamping rod (7) and the upper section of the L-shaped abutting rod (8) are circular.

4. The immunofluorescence anti-detachment washer according to claim 1, wherein: washing tank (2) upper portion left side front side intercommunication has inlet channel (19), both sides all communicate around washing tank (2) right side wall bottom has drainage tube (20), still install the gate valve on drainage tube (20).

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