CN210604944U - Quantitative component of magnetic resonance imaging device and magnetic resonance imaging device - Google Patents

Quantitative component of magnetic resonance imaging device and magnetic resonance imaging device Download PDF

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CN210604944U
CN210604944U CN201920933002.4U CN201920933002U CN210604944U CN 210604944 U CN210604944 U CN 210604944U CN 201920933002 U CN201920933002 U CN 201920933002U CN 210604944 U CN210604944 U CN 210604944U
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reagent
temperature
heat exchange
liquid
tank
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韩鸿宾
和清源
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Peking University Third Hospital
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Peking University Third Hospital
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Abstract

The quantitative component of the magnetic resonance imaging device comprises a reagent seat (10), a heat exchange tube part (16), a water tank (20), a pump (30), a second temperature sensor (40) and a controller (50). The reagent seat is provided with a temperature control cavity and also comprises a heat exchange pipe part (16), a liquid inlet (12) and a liquid outlet (14). The heat exchange tube portion passes through the temperature control chamber. The water tank includes a tank body (21), a water supply pipe (22), a water return pipe (23), and a first temperature sensor (24). The pump is arranged on the water supply pipe. The second temperature sensor measures a temperature of the reagent in the heat exchange tube portion. The controller is connected with the pump, the second temperature sensor and the first temperature sensor, and controls the pump according to the temperature of the reagent so that the reagent is kept at a preset reagent temperature. The quantitative assembly can provide more accurate imaging results. The utility model also provides a magnetic resonance imaging device including above-mentioned ration subassembly.

Description

Quantitative component of magnetic resonance imaging device and magnetic resonance imaging device
Technical Field
The present invention relates to a quantitative assembly, and more particularly to a quantitative assembly for a magnetic resonance imaging apparatus and a magnetic resonance imaging apparatus including the same.
Background
Animal experiments can avoid risks brought by human experiments in biomedical research, and magnetic resonance imaging is sometimes adopted to complete experiments. In some experiments, when the magnetic resonance imaging of animals is performed, a reagent needs to be arranged in the coil, and the reagent is affected by the ambient temperature and interferes with the accuracy of the final experimental result.
SUMMERY OF THE UTILITY MODEL
The utility model aims at providing a magnetic resonance imaging device's ration subassembly, it can avoid reagent to receive ambient temperature's influence in the magnetic resonance imaging that accompanies the reagent and go on, provides more accurate formation of image result.
Another object of the present invention is to provide a magnetic resonance imaging apparatus, which can avoid the reagent from being affected by the ambient temperature during the magnetic resonance imaging with the reagent, and provide a more accurate imaging result.
The utility model provides a magnetic resonance imaging device's ration subassembly, including a reagent seat, a water tank, a pump machine, a second temperature sensor and a controller. The wall of the reagent seat is internally provided with a temperature control cavity, and the reagent seat is also provided with a plurality of heat exchange pipe parts, a liquid inlet and a liquid outlet. The heat exchange tube portion passes through the temperature control chamber, and when the reagent seat is disposed on a receiving coil of the magnetic resonance imaging apparatus, the axis of the heat exchange tube portion is parallel to the axis of the receiving coil, and both ends of the heat exchange tube portion extend to the surface of the reagent seat 10 along the axial direction thereof. The liquid inlet is arranged on the surface of the reagent seat and communicated with the temperature control cavity. The liquid outlet is arranged on the surface of the reagent seat and communicated with the temperature control cavity. The water tank comprises a tank body, a water supply pipe, a water return pipe and a first temperature sensor. The tank is capable of holding a liquid. The water supply pipe is respectively communicated with the box body and the liquid inlet. The return pipe is respectively communicated with the box body and the liquid outlet. The probe of the second temperature sensor is arranged in the heat exchange tube part and can measure the temperature of the reagent in the heat exchange tube part. The pump machine sets up in the delivery pipe and can carry the liquid in the box to the control by temperature change chamber. The probe of the second temperature sensor can be disposed within the heat exchange tube portion and measure the temperature of the reagent within the heat exchange tube portion. The controller is respectively signal connection pump machine, second temperature sensor and first temperature sensor, and the controller can be according to the velocity of flow of temperature control pump machine to temperature control chamber transport liquid of the interior reagent of heat exchange tube portion to keep at a predetermined reagent temperature through the heat exchange control heat exchange tube portion of the interior reagent of liquid and heat exchange tube portion.
According to the quantitative assembly of the magnetic resonance imaging device, the controller can control the speed of the pump to convey liquid to the temperature control cavity according to the temperature of the reagent in the heat exchange tube part, and the reagent in the heat exchange tube part is controlled to be kept at a preset reagent temperature through heat exchange between the liquid and the reagent in the heat exchange tube part. The influence of the environmental temperature on the reagent is avoided, and a more accurate imaging result is provided.
In an exemplary embodiment of the dosing assembly of the magnetic resonance imaging apparatus, the reagent support is cylindrical and the axis of the reagent support is parallel to the axis of the receiving coil when the reagent support is arranged in the receiving coil of the magnetic resonance imaging apparatus.
In an exemplary embodiment of the dosing assembly of the magnetic resonance imaging apparatus, the reagent support is semi-cylindrical and the axis of the reagent support is parallel to the axis of the receiving coil when the reagent support is arranged in the receiving coil of the magnetic resonance imaging apparatus.
In an exemplary embodiment of the dosing assembly of the magnetic resonance imaging device, the water reservoir further comprises a heating element and a cooling element. The heating member is arranged in the box body and can heat liquid in the box body. The refrigeration piece sets up in the box and can be to the liquid cooling in the box. The controller is signal connection heating member and refrigeration piece respectively, and the controller can heat or refrigerate the piece according to the temperature control heating member of liquid in the box to through the temperature of the liquid in the heating or cooling control box.
In an exemplary embodiment of the dosing assembly of the magnetic resonance imaging apparatus, the dosing assembly further comprises a cryogenically controlled device, which is arranged at the reagent seat.
In an exemplary embodiment of the quantitative assembly of the magnetic resonance imaging apparatus, the quantitative assembly further comprises an upper computer, the upper computer is in signal connection with the controller and the second temperature sensor respectively, the upper computer can send an instruction to the controller to adjust the temperature of the preset reagent, and the upper computer can also record the temperature of the reagent in the heat exchange tube part measured by the second temperature sensor.
In an exemplary embodiment of the quantitative assembly of the magnetic resonance imaging apparatus, the quantitative assembly further comprises a check valve disposed in the water supply pipe and capable of preventing the liquid in the temperature-controlled cavity from flowing to the tank.
In an exemplary embodiment of the quantitative assembly of the magnetic resonance imaging apparatus, the surfaces of the reagent holder, the tank, the water supply pipe and the water return pipe are provided with thermal insulation layers.
In an exemplary embodiment of the dosing assembly of the magnetic resonance imaging device, the first temperature sensor is a thermistor and the second temperature sensor is a fluorescent fiber optic temperature sensor.
The utility model also provides a magnetic resonance imaging device, including receiving coil and an foretell ration subassembly. The reagent seat is coaxially arranged through the receiving coil, and the axis of the heat exchange tube part is parallel to the axis of the receiving coil.
The above features, technical features, advantages and implementations of the quantitative component and the magnetic resonance imaging apparatus of the magnetic resonance imaging apparatus will be further explained in a clearly understandable manner by referring to the following description of the preferred embodiments in conjunction with the accompanying drawings.
Drawings
The following drawings are only schematic illustrations and explanations of the present invention, and do not limit the scope of the present invention.
Fig. 1 is a schematic diagram illustrating an exemplary embodiment of a dosing assembly of a magnetic resonance imaging apparatus.
Fig. 2 is a partial schematic view illustrating another exemplary embodiment of a water tank.
Fig. 3 is a schematic diagram illustrating a further exemplary embodiment of a dosing assembly of the magnetic resonance imaging apparatus.
Fig. 4 is a partial schematic structural diagram of an exemplary embodiment of a magnetic resonance imaging apparatus.
Description of the reference symbols
10 reagent seat
12 liquid inlet
14 liquid outlet
16 heat exchange tube part
18 low temperature control device
20 water tank
21 box body
22 water supply pipe
23 return pipe
24 first temperature sensor
25 heating element
26 Cooling element
30 pump machine
40 second temperature sensor
42 Probe
50 controller
60 upper computer
70 one-way valve
80 receive the coil.
Detailed Description
In order to clearly understand the technical features, objects, and effects of the present invention, embodiments of the present invention will be described with reference to the accompanying drawings, wherein the same reference numerals in the drawings denote the same or similar components.
"exemplary" means "serving as an example, instance, or illustration" herein, and any illustration, embodiment, or steps described as "exemplary" herein should not be construed as a preferred or advantageous alternative.
For the sake of simplicity, only the parts relevant to the present invention are schematically shown in the drawings, and they do not represent the actual structure as a product. In addition, for simplicity and clarity of understanding, only one of the components having the same structure or function is schematically illustrated or labeled in some of the drawings.
In this context, "horizontal", "axial registration", etc. are not strictly mathematical and/or geometric limitations, but also include tolerances as would be understood by a person skilled in the art and allowed for manufacturing or use, etc.
Fig. 1 is a schematic diagram illustrating an exemplary embodiment of a dosing assembly of a magnetic resonance imaging apparatus. As shown in fig. 1, the dosing assembly of the mri apparatus includes a reagent holder 10, a water tank 20, a pump 30, a second temperature sensor 40, and a controller 50.
As shown in FIG. 1, the reagent seat 10 is cylindrical, and a temperature control chamber (not shown) is formed in the wall of the reagent seat, i.e. the wall of the reagent seat 10 is a hollow wall, and the temperature control chamber is located between the inner surface and the outer surface of the wall of the reagent seat 10. The temperature control cavity of the reagent seat 10 can contain liquid. The reagent pad 10 also has a plurality of heat exchange tube portions 16 (only one of which is identified), an inlet port 12 and an outlet port 14. The heat exchange tube portion 16 passes through the temperature control chamber, and when the reagent holder 10 is disposed on a receiving coil of the mri apparatus, the axis of the heat exchange tube portion 16 is parallel to the axis of the receiving coil 80 and the axis of the reagent holder 10 (see fig. 4), and both ends of the heat exchange tube portion 16 extend along the axes thereof to both axial end faces of the reagent holder 10. The heat exchange tube 16 may have one end communicating with the axial end surface of the reagent pad 10, or may have both ends communicating with the axial end surface of the reagent pad 10 so as to penetrate the entire reagent pad 10. In the illustrated embodiment, at least one end of the heat exchange tube portion 16 is sealed by a plug, and the heat exchange tube portion 16 may be filled with a reagent that can be developed on the final image. The liquid inlet 12 and the liquid outlet 14 are respectively disposed on the surface of the reagent seat 10 and are communicated with the temperature control cavity. After the liquid inlet 12 and the liquid outlet 14 are arranged, the liquid can be circulated into the temperature control cavity of the reagent seat 10, so as to change the temperature of the reagent seat 10. In the exemplary embodiment, to avoid heat loss, the surface of the reagent pad 10 is provided with a thermal insulating layer. Although the reagent pad 10 is cylindrical in the exemplary embodiment, it is not limited thereto, and the reagent pad 10 may be semi-cylindrical (refer to fig. 3) or other shapes in other exemplary embodiments.
The water tank 20 includes a tank body 21, a water supply pipe 22, a return pipe 23, and a first temperature sensor 24. The tank 21 is capable of holding a liquid, which may be water or another liquid with a good thermal conductivity, which may be heated to above ambient temperature in advance, or cooled to below ambient temperature in advance. In the illustrated embodiment, the tank 21 has transparent outer walls to facilitate viewing of the liquid level. However, without limitation, in other exemplary embodiments, the housing 21 may be of an opaque design. The water supply pipe 22 communicates with the tank 21 and the liquid inlet 12, respectively. The return pipe 23 communicates with the tank 21 and the liquid outlet 14, respectively. The pump 30 is disposed on the water supply pipe 22, which may be a peristaltic pump, and is capable of conveying the liquid in the tank 21 to the temperature control chamber, and the liquid in the temperature control chamber can return to the tank 21 through the return pipe 23, and can continuously exchange heat with the reagent in the heat exchange pipe portion 16 through the flow of the liquid, thereby performing the function of adjusting the temperature of the reagent. In the exemplary embodiment, also to avoid heat loss, the surfaces of the tank 21, the water supply pipe 22, and the water return pipe 23 are also provided with heat insulating layers. The first temperature sensor 24 is a low-cost thermistor that is disposed in the tank 21 and can measure the temperature of the liquid in the tank 21.
The second temperature sensor 40 is a fluorescence optical fiber type temperature sensor, which can better adapt to the magnetic field environment and has better stability and precision, the fluorescence optical fiber type temperature sensor 40 has only one probe 42 which is marked in the figure, the probes 42 can be arranged in the heat exchange tube parts 16 in a one-to-one correspondence manner, and the temperature of the reagent in the heat exchange tube parts 16 can be measured. The controller 50 is in signal connection with the pump 30, the second temperature sensor 40 and the first temperature sensor 24, respectively. The controller 50 may be a single chip or other processing chip capable of receiving the real-time temperature of the reagent in the heat exchange tube portion 16 and the liquid in the tank 21 and adjusting the flow rate of the liquid delivered by the pump 30 to the temperature controlled chamber according to the temperature. The reagent in the heat exchange tube section 16 can be heated or cooled by heat exchange between the high or low temperature liquid entering the temperature controlled chamber and the reagent in the heat exchange tube section 16. The controller 50 controls the reagent in the heat exchange tube portion 16 to be maintained at a predetermined reagent temperature in the manner described above.
When the quantitative assembly of the magnetic resonance imaging device is used, for example, for accurately and quantitatively analyzing the concentration of the molecular probe in the measurement of the extracellular space of the brain, or in other experiments with the magnetic resonance imaging device, a liquid with a certain temperature is added into the box body 21, and the controller 50 can control the pump 30 to deliver the liquid to the temperature control cavity according to the temperature of the reagent in the heat exchange tube part 16, and control the reagent in the heat exchange tube part 16 to be kept at a preset reagent temperature through the heat exchange between the liquid and the reagent in the heat exchange tube part 16. The experiment is carried out under the condition, so that the influence of the environmental temperature on the reagent is avoided, and a more accurate imaging result is provided.
In an exemplary embodiment, referring to fig. 1, the dosing assembly further comprises a cryogenic control device 18. The low temperature control device 18 is disposed in a cavity defined by the inner surface of the reagent seat 10. The cryogenic control device 18 is able to maintain the temperature of the tissue being measured from the temperature of the liquid in the reagent pad 10, providing more accurate imaging results.
In an exemplary embodiment, referring to fig. 1, the quantitative assembly further includes an upper computer 60 in signal connection with the controller 50 and the second temperature sensor 40, respectively, the upper computer 60 can send an instruction to the controller 50 to adjust the preset reagent temperature, and the upper computer 60 can record the temperature of the reagent in the heat exchange tube portion 16 measured by the second temperature sensor 40. Thereby facilitating operation and monitoring.
In an exemplary embodiment, referring to fig. 1, the dosing assembly further comprises a one-way valve 70. The check valve 70 is disposed on the water supply pipe 22 and can prevent the liquid in the temperature control chamber from flowing to the tank body 21, thereby preventing temperature loss due to liquid backflow and further saving energy.
Modulation, FIG. 2, is a partial schematic diagram illustrating another exemplary embodiment of a tank. Referring to fig. 2, the water tank 20 further includes a heating member 25 and a cooling member 26. The heating member 25 is a heating plate provided in the casing 21 and capable of heating the liquid in the casing 21. The cooling member 26 is a semiconductor cooling plate disposed in the case 21 and capable of cooling the liquid in the case 21. The controller 50 is in signal connection with the heating element and the cooling element 26, respectively, and is capable of controlling the heating or cooling element 26 according to the temperature of the liquid in the tank and controlling the temperature of the liquid in the tank by heating or cooling. In the exemplary embodiment, controller 50 may output the duty cycle of the waveforms in a Pulse Width modulated (Pulse Width PWM) manner to control the output power of heating element 25 and cooling element 26. The liquid in the box body 21 can be automatically adjusted to the optimal temperature by controlling the heating element 25 or the refrigerating element 26 through the controller 50, the process is more accurate, the liquid temperature is adjusted by replacing the manual work, and the use is more convenient.
Fig. 3 is a schematic diagram illustrating a further exemplary embodiment of a dosing assembly of the magnetic resonance imaging apparatus. Referring to fig. 3, the reagent pad 10 has a semi-cylindrical shape, and an axis of the reagent pad 10 is parallel to an axis of a receiving coil of the mri apparatus when the reagent pad 10 is disposed on the receiving coil. Thereby facilitating the magnetic resonance imaging apparatus to perform imaging from another angle.
The present invention also provides a magnetic resonance imaging apparatus, and fig. 4 is a partial structure diagram illustrating an exemplary embodiment of the magnetic resonance imaging apparatus. Referring to fig. 4, the magnetic resonance imaging apparatus includes a receiving coil 80 and a quantification assembly as described above. The reagent pad 10 is coaxially threaded through the receiving coil 80 with the axis of the heat exchange tube portion 16 parallel to the axis of the receiving coil.
It should be understood that although the present description has been described in terms of various embodiments, not every embodiment includes only a single embodiment, and such description is for clarity purposes only, and those skilled in the art will recognize that the embodiments described herein may be combined as suitable to form other embodiments, as will be appreciated by those skilled in the art.
The above list of details is only for the practical examples of the present invention, and they are not intended to limit the scope of the present invention, and all equivalent embodiments or modifications, such as combinations, divisions or repetitions of the features, which do not depart from the technical spirit of the present invention, should be included in the scope of the present invention.

Claims (10)

1. A quantification assembly for a magnetic resonance imaging apparatus, comprising:
a reagent pad (10) capable of being disposed within a receiving coil of the mri apparatus, a temperature-controlled chamber being formed within the reagent pad (10), the reagent pad (10) comprising:
a plurality of heat exchange tube parts (16), wherein the heat exchange tube parts (16) penetrate through the temperature control cavity, the axis of the heat exchange tube parts (16) is parallel to the axis of a receiving coil of the magnetic resonance imaging device when the reagent seat (10) is arranged on the receiving coil, and two ends of the heat exchange tube parts (16) extend to the surface of the reagent seat (10) along the axial direction of the heat exchange tube parts;
a liquid inlet (12) arranged on the surface of the reagent seat (10) and communicated with the temperature control cavity, and
a liquid outlet (14) which is arranged on the surface of the reagent seat (10) and communicated with the temperature control cavity;
a water tank (20) comprising:
a tank (21) capable of storing a liquid,
a water supply pipe (22) respectively communicating the tank body (21) and the liquid inlet (12),
a return pipe (23) communicating with the tank (21) and the liquid outlet (14), respectively, and
a first temperature sensor (24) disposed in the tank (21) and capable of measuring the temperature of the liquid in the tank (21);
a pump (30) provided to the water supply pipe (22) and capable of delivering the liquid in the tank (21) to the temperature control chamber;
a second temperature sensor (40) having a probe disposed in said heat exchange tube portion (16) and capable of measuring the temperature of the reagent in said heat exchange tube portion (16); and
and the controller (50) is in signal connection with the pump (30), the second temperature sensor (40) and the first temperature sensor (24), the controller (50) can control the flow rate of liquid conveyed to the temperature control cavity by the pump (30) according to the temperature of the reagent in the heat exchange pipe part (16) and the temperature of liquid in the box body (21), and control the reagent in the heat exchange pipe part (16) to be kept at a preset reagent temperature through heat exchange between the liquid and the reagent in the heat exchange pipe part (16).
2. The dosing assembly according to claim 1, characterized in that the reagent holder (10) is cylindrical and that the axis of the reagent holder (10) is parallel to the axis of the receiving coil when the reagent holder (10) is arranged in the receiving coil.
3. The dosing assembly according to claim 1, wherein the reagent pad (10) is semi-cylindrical and the axis of the reagent pad (10) is parallel to the axis of the receiving coil when the reagent pad (10) is arranged in the receiving coil.
4. Dosing assembly according to claim 1, wherein the water tank (20) further comprises:
a heating member (25) which is provided in the tank (21) and is capable of heating the liquid in the tank (21); and
a refrigerating member (26) disposed inside the tank (21) and capable of cooling the liquid inside the tank (21);
the controller (50) is in signal connection with the heating element (25) and the refrigerating element (26) respectively, and the controller (50) can control the heating element (25) or the refrigerating element (26) according to the temperature of the liquid in the box body (21) and control the temperature of the liquid in the box body (21) through heating or cooling.
5. Dosing assembly according to claim 1, further comprising a cryogenic control device (18) arranged in the reagent pad (10).
6. The dosing assembly of claim 1, further comprising an upper computer (60) in signal communication with the controller (50) and the second temperature sensor (40), the upper computer (60) being capable of sending instructions to the controller (50) to adjust the predetermined reagent temperature, the upper computer (60) being further capable of recording the temperature of the reagent in the heat exchange tube portion (16) as measured by the second temperature sensor (40).
7. The dosing assembly according to claim 1, further comprising a one-way valve (70) disposed in the water supply tube (22) and adapted to prevent liquid in the temperature-controlled chamber from flowing to the tank (21).
8. Dosing assembly according to claim 1, characterized in that the surfaces of the reagent holder (10), the tank (21), the water supply pipe (22) and the water return pipe (23) are provided with a heat insulating layer.
9. Dosing assembly according to claim 1, wherein the first temperature sensor (24) is a thermistor and the second temperature sensor (40) is a fluorescent fiber optic temperature sensor.
10. A magnetic resonance imaging apparatus, characterized by comprising:
a receiving coil (80); and
a dosing assembly according to any of claims 1-9, the reagent pad (10) being arranged through the receiving coil (80), the axis of the heat exchange tube portion (16) being parallel to the axis of the receiving coil.
CN201920933002.4U 2019-06-20 2019-06-20 Quantitative component of magnetic resonance imaging device and magnetic resonance imaging device Active CN210604944U (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113406543A (en) * 2021-08-19 2021-09-17 深圳市联影高端医疗装备创新研究院 Temperature regulation and control system
WO2022110136A1 (en) * 2020-11-27 2022-06-02 中国科学院深圳先进技术研究院 Cooling system for radio frequency coil, and magnetic resonance imaging device

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022110136A1 (en) * 2020-11-27 2022-06-02 中国科学院深圳先进技术研究院 Cooling system for radio frequency coil, and magnetic resonance imaging device
CN113406543A (en) * 2021-08-19 2021-09-17 深圳市联影高端医疗装备创新研究院 Temperature regulation and control system

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