CN210596073U - Optical axis space attitude adjusting device of microscopic monitoring system of cell fermentation tank - Google Patents

Optical axis space attitude adjusting device of microscopic monitoring system of cell fermentation tank Download PDF

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Publication number
CN210596073U
CN210596073U CN201921098063.XU CN201921098063U CN210596073U CN 210596073 U CN210596073 U CN 210596073U CN 201921098063 U CN201921098063 U CN 201921098063U CN 210596073 U CN210596073 U CN 210596073U
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CN
China
Prior art keywords
optical axis
adjusting mechanism
monitoring system
microscope
support frame
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Expired - Fee Related
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CN201921098063.XU
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Chinese (zh)
Inventor
李琦
柳金明
向阳
宁旭
张合
闫帅
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Changchun University of Science and Technology
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Changchun University of Science and Technology
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Priority to CN201921098063.XU priority Critical patent/CN210596073U/en
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Expired - Fee Related legal-status Critical Current
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Abstract

The utility model discloses a space attitude adjusting device of an optical axis of a microscopic monitoring system of a cell fermentation tank, which comprises a base frame, wherein a height moving adjusting platform is fixedly arranged on the base frame, a load plate is slidably connected on the height moving adjusting platform, a microscope adjusting mechanism and an illumination rotation adjusting mechanism are sequentially and fixedly arranged on the load plate, the illumination rotation adjusting mechanism comprises a base, a first support frame is fixedly connected on the base, an illuminator is fixedly arranged on the first support frame, the microscope adjusting mechanism comprises a second support frame, a clamping device is fixedly arranged on the second support frame, a microscope device is fixedly arranged on the clamping device, and the illumination rotation adjusting mechanism is fixedly connected with a moving platform; the utility model discloses according to the size of different series cell fermentation tanks, the side-to-side motion is realized to the interval of the flexible regulation illumination end of adjustment mobile station and microscope camera lens, and the adjustment height moves about the adjustment table and realizes the up-and-down motion of optical axis, and then promotes the discernment and the monitoring precision to the cell.

Description

Optical axis space attitude adjusting device of microscopic monitoring system of cell fermentation tank
Technical Field
The utility model relates to a biomedical engineering field especially relates to a micro-monitoring system's of cell fermentation cylinder optical axis space attitude adjustment device.
Background
In the cell fermentation tank monitoring process, because of microscope and fixed irradiation light source need accurate adjustment countershaft, if the deviation appears in the diaxon or the matching nature is not good, will lead to cell identification to appear the deviation, a series of problems such as image template matching is unsuccessful to lead to the unstable phenomenon of test to take place. In the prior art, the optical axis posture adjusting device of the cell fermentation tank monitoring system is assembled and constructed by the existing optical adjusting frame and the mechanical adjusting table, and the problem that a lens interface and an illumination interface are not matched easily occurs, if a lens is a lens cone with phi 40mm, and the existing commercial optical adjusting frame does not have a corresponding clamping device, the lens and the illumination interface are required to be excessively connected, an angle error exists between the optical axis and the reference surface of the adjusting table due to the excessive connection, and the coupling and redundancy of the angle during the spatial dimension adjustment can occur when the adjusting table is adjusted;
in addition, the existing optical adjusting frame and mechanical adjusting table are assembled and built, aiming at a cell fermentation tank monitoring system, the adjusting link is complicated and unstable, each adjusting table is provided with a respective locking and fine adjusting mechanism and a respective circuit and driver, and therefore the cell image alignment and identification process is too complicated;
present optical adjustment frame is relatively poor with mechanical adjustment platform assembly mode precision, because individual adjustment platform all is universal mechanism, so the precision must not be very high, to cell fermentation tank monitoring system optical axis space attitude adjustment process, the angular adjustment of optical axis all is more than hierarchical, consequently present optical adjustment frame is too redundant with mechanical adjusting device's optical adjustment frame, and the mechanical benchmark and the location interface of different adjustment frames all have the difference, microscope head and illumination end collocation are not good, the loaded down with trivial details and unstable factor of adjustment link, directly lead to cell monitoring process stability to reduce.
SUMMERY OF THE UTILITY MODEL
The utility model aims at providing a space posture adjustment device of micro-monitoring system optical axis of cell fermentation cylinder to solve the problem that above-mentioned prior art exists.
In order to achieve the above object, the utility model provides a following scheme: the utility model provides a space gesture adjusting device of microscopic monitoring system optical axis of cell fermentation cylinder, which comprises a base frame, the fixed mounting height adjustment platform that moves about on the bed frame, the height has the load board of sliding connection on the adjustment platform that moves about, fixed mounting microscope guiding mechanism, the rotatory guiding mechanism of illumination in proper order on the load board, the rotatory guiding mechanism of illumination includes the base, the first support frame of fixedly connected with on the base, fixed mounting illuminator on the first support frame, the illuminator surface has cup jointed the triaxial and has revoluted the dabber, the triaxial revolutes the dabber coupling and has had joint bearing, microscope guiding mechanism includes the second support frame, fixed mounting clamping device on the second support frame, fixed mounting microscope camera lens on the clamping device, rotatory guiding mechanism of illumination and moving platform fixed connection.
Preferably, a hand wheel is coupled to the illumination rotation adjustment mechanism.
Preferably, the height adjustment platform that moves about includes first motor, first slide rail, and first motor coupling has first lead screw, first lead screw threaded connection has the slide, the both ends and the first slide rail sliding connection of slide, slide and load board coupling, a plurality of through-hole has been seted up on the slide, a plurality of logical groove has been seted up on the load board.
Preferably, the mobile station comprises a second motor, the second motor is connected with a second lead screw in a shaft coupling mode, the second lead screw is connected with a base in a threaded mode, and two ends of the base are connected with a second sliding rail in a sliding mode.
Preferably, the first support frame comprises a first support plate, a second support plate and a third support plate, the first support plate is fixedly connected with the second support plate, one end of the third support plate is connected with the first support plate, and the other end of the third support plate is connected with the second support plate.
Preferably, the included angle between the first support plate and the second support plate ranges from 60 degrees to 90 degrees.
The utility model discloses a following technological effect: the utility model adjusts the distance between the illumination end and the microscope lens of the mobile station to realize the left-right movement and adjusts the height moving adjusting station to realize the up-down movement of the optical axis according to the sizes of different series cell fermentation tanks; adjusting the axial angle of the load plate and the optical axis of the microscope lens to make the selected monitoring cells fall in the center of the visual field, and moving back and forth by adjusting the base frame; the adjustment hand wheel relies on high accuracy joint bearing's the degree of freedom that revolutes, realizes the adjustment of illumination end every single move, azimuth direction for it is coaxial with the microscope lens optical axis to make the cell light field of monitoring even and sufficient improvement optical axis adjustment accuracy, and then promotes discernment and monitoring accuracy to the cell.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required to be used in the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without inventive labor.
Fig. 1 is a schematic structural view of the present invention;
FIG. 2 is a front view of the height adjustment table of the present invention;
fig. 3 is a front view of the load board of the present invention;
fig. 4 is a front view of the illumination rotation adjustment mechanism of the present invention;
fig. 5 is a front view of the microscope adjustment mechanism of the present invention;
fig. 6 is a rotation schematic diagram of the illumination rotation adjustment mechanism of the present invention;
the microscope comprises a base frame 1, a first motor 2, a first slide rail 3, a first lead screw 4, a slide plate 5, a load plate 6, a height moving adjusting platform 7, a lighting rotation adjusting mechanism 8, a microscope adjusting mechanism 9, a base 10, a first support frame 11, a second support frame 12, a clamping device 13, a moving platform 14, a second motor 15, a second lead screw 16, a universal wheel 17, a second slide rail 18, a hand wheel 19, a through hole 20, a through groove 21, a lighting device 22, a first support plate 23, a second support plate 24, a third support plate 25 and a microscope lens 26.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
In order to make the above objects, features and advantages of the present invention more comprehensible, the present invention is described in detail with reference to the accompanying drawings and the detailed description.
Referring to fig. 1-5, the utility model provides an optical axis space attitude adjusting device of a microscopic monitoring system of a cell fermentation tank, which comprises a base frame 1, a height moving adjusting platform 7 is fixedly installed on the base frame 1, a load plate 6 is connected on the height moving adjusting platform 7, the height moving adjusting platform 7 moves up and down to drive the load plate 6 to move up and down, a microscope adjusting mechanism 9 and an illumination rotary adjusting mechanism 8 are sequentially and fixedly installed on the load plate 6, the cell fermentation tank is fixed between the microscope adjusting mechanism 9 and the illumination rotary adjusting mechanism 8 to adjust the position of the cell fermentation tank, so that the illumination rotary adjusting mechanism 8, the microscope adjusting mechanism 9 and cells to be monitored in the cell fermentation tank are positioned on the same horizontal line, the illumination rotary adjusting mechanism 8 comprises a base 10, a first support frame 11 is fixedly connected on the base 10, fixedly mounted illuminator 22 on the first support frame 11, illuminator 22 surface has cup jointed the triaxial and has revolved the dabber, the triaxial revolves dabber and 19 coupling of hand wheel, the triaxial revolves the dabber coupling and has had joint bearing for the every single move angle of adjustment illuminator 22, microscope guiding mechanism 9 includes second support frame 12, fixedly mounted clamping device 13 on the second support frame 12, fixedly mounted microscope camera lens 26 on the clamping device 13.
Furthermore, a hand wheel 19 is coupled to the illumination rotation adjusting mechanism 8, the hand wheel 19 is adjusted to make the optical axis of the microscope lens coaxial with the cell to be monitored, and the optical field of the monitored cell is uniform and full, and the illumination rotation adjusting mechanism 8 is fixedly connected with the mobile station 14.
Further, the height moving adjusting table 7 comprises a first motor 2 and a first slide rail 3, the first motor 2 is connected with a first lead screw 4 through a coupler, the first lead screw 4 is in threaded connection with a slide plate 5, two ends of the slide plate 5 are in sliding connection with the first slide rail 3, the slide plate 5 is in shaft connection with a load plate 6, the first motor 2 drives the first lead screw 4 to rotate, the lead screw drives the slide plate 5 to move up and down on the first slide rail 3, so as to drive the load plate 6 to move up and down, a plurality of through holes 20 are formed in the slide plate 5, a plurality of through grooves 21 are formed in the load plate 6, the through holes 20 are fixed with the through grooves 21 through pin shafts, and the device can realize rotation of the load plate 6.
Further, the mobile station 14 includes a second motor 15, the second motor 15 is connected with a second lead screw 16 through a coupler, the second lead screw 16 is in threaded connection with the base 10, two ends of the base 10 are in sliding connection with a second slide rail 18, the second motor 15 drives the second lead screw 16 to rotate, and then the mobile station 14 is driven to move left and right, so that the distance between the lighting rotary adjusting mechanism 8 and the microscope device can be adjusted, and the cell fermentation tanks with different diameters can be conveniently used.
Further, the first support frame 11 includes a first support plate 23, a second support plate 24 and a third support plate 25, the first support plate 23 is fixedly connected with the second support plate 24, one end of the third support plate 25 is connected with the first support plate 23, and the other end of the third support plate 25 is connected with the second support plate 24, so as to support the illumination rotation adjusting mechanism 8.
Further, the included angle between the first supporting plate 23 and the second supporting plate 24 ranges from 60 degrees to 90 degrees.
Furthermore, the bottom of the base frame 1 is coupled with a universal wheel 17, so that the whole device can move forwards and backwards, and the distance between the base frame 1 and the cell fermentation tank can be conveniently controlled.
As shown in fig. 6, the rotation angle of the illumination end is θ, and according to the angle relationship shown in the figure, θ is β, since the rotation angle is small, the rotation arc length a ≈ b, tan β ≈ a/L ═ b/L', b ═ 3mm, and L ═ 115mm, β ≈ 0.026 ≈ 1.5 °.
The angle of rotation of the illumination segment is θ, which is shown in the angle relation, and θ is β, and since the angle of rotation is small, tan β is R/L, R is pushed by the handwheel 19, the recommended pitch of the rod thread of the handwheel 19 is 0.1mm, L is 350mm, and β is 0.0003 is 1'.
The angle of rotation of the illumination end is θ, which is shown in the angle relation, θ is β, and since the angle of rotation is small, tan β is R/L, R is pushed by the handwheel 19, the recommended pitch of the rod thread of the handwheel 19 is 0.1mm, L is 350mm, β is 0.0003 is 1'.
In the description of the present invention, it is to be understood that the terms "longitudinal", "lateral", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", and the like indicate orientations or positional relationships based on those shown in the drawings, and are merely for convenience of description of the present invention, and do not indicate or imply that the device or element so referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore, should not be construed as limiting the present invention.
The above-mentioned embodiments are only intended to describe the preferred embodiments of the present invention, but not to limit the scope of the present invention, and those skilled in the art should also be able to make various modifications and improvements to the technical solution of the present invention without departing from the spirit of the present invention, and all such modifications and improvements are intended to fall within the scope of the present invention as defined in the appended claims.

Claims (7)

1. The utility model provides a microscopic monitoring system's of cell fermentation cylinder optical axis space attitude adjusting device which characterized in that: the microscope adjusting mechanism comprises a base frame (1), wherein a height moving adjusting platform (7) is fixedly installed on the base frame (1), a load plate (6) is connected onto the height moving adjusting platform (7) in a sliding manner, a microscope adjusting mechanism (9) and an illumination rotating adjusting mechanism (8) are sequentially and fixedly installed on the load plate (6), the illumination rotating adjusting mechanism (8) comprises a base (10), a first support frame (11) is fixedly connected onto the base (10), an illuminator (22) is fixedly installed onto the first support frame (11), a three-shaft revolving mandrel is sleeved on the outer surface of the illuminator (22), a joint bearing is axially connected onto the three-shaft revolving mandrel, the microscope adjusting mechanism (9) comprises a second support frame (12), a clamping device (13) is fixedly installed onto the second support frame (12), and a microscope lens (26) is fixedly installed onto the clamping device (13), the illumination rotation adjusting mechanism (8) is fixedly connected with the mobile station (14).
2. The optical axis spatial attitude adjusting device of the microscopic monitoring system of the cell fermenter according to claim 1, further comprising: a hand wheel (19) is coupled on the illumination rotation adjusting mechanism (8).
3. The optical axis spatial attitude adjusting device of the microscopic monitoring system of the cell fermenter according to claim 1, further comprising: height adjustment platform (7) that moves about includes first motor (2), first slide rail (3), and first motor (2) coupling has first lead screw (4), first lead screw (4) threaded connection has slide (5), the both ends and first slide rail (3) sliding connection of slide (5), slide (5) and load board (6) coupling, a plurality of through-hole (20) have been seted up on slide (5), logical groove (21) have been seted up to a plurality of on load board (6).
4. The optical axis spatial attitude adjusting device of the microscopic monitoring system of the cell fermenter according to claim 1, further comprising: the mobile station (14) comprises a second motor (15), the second motor (15) is connected with a second lead screw (16) in a shaft mode, the second lead screw (16) is connected with the base (10) in a threaded mode, and two ends of the base (10) are connected with a second sliding rail (18) in a sliding mode.
5. The optical axis spatial attitude adjusting device of the microscopic monitoring system of the cell fermenter according to claim 1, further comprising: first support frame (11) include first backup pad (23), second backup pad (24), third backup pad (25), first backup pad (23) and second backup pad (24) fixed connection, the one end and the first backup pad (23) of third backup pad (25) are connected, the other end and the second backup pad (24) of third backup pad (25) are connected.
6. The optical axis spatial attitude adjusting apparatus of the microscopic monitoring system of the cell fermenter according to claim 5, wherein: the included angle between the first supporting plate (23) and the second supporting plate (24) ranges from 60 degrees to 90 degrees.
7. The optical axis spatial attitude adjusting device of the microscopic monitoring system of the cell fermenter according to claim 1, further comprising: the bottom of the base frame (1) is coupled with a universal wheel (17).
CN201921098063.XU 2019-07-15 2019-07-15 Optical axis space attitude adjusting device of microscopic monitoring system of cell fermentation tank Expired - Fee Related CN210596073U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201921098063.XU CN210596073U (en) 2019-07-15 2019-07-15 Optical axis space attitude adjusting device of microscopic monitoring system of cell fermentation tank

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201921098063.XU CN210596073U (en) 2019-07-15 2019-07-15 Optical axis space attitude adjusting device of microscopic monitoring system of cell fermentation tank

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110305782A (en) * 2019-07-15 2019-10-08 长春理工大学 The optical axis spatial attitude of cell fermentation tank microscopic monitoring system adjusts device

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110305782A (en) * 2019-07-15 2019-10-08 长春理工大学 The optical axis spatial attitude of cell fermentation tank microscopic monitoring system adjusts device
CN110305782B (en) * 2019-07-15 2024-02-20 长春理工大学 Optical axis space posture adjusting device of microscopic monitoring system of cell fermentation tank

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CF01 Termination of patent right due to non-payment of annual fee
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Granted publication date: 20200522

Termination date: 20210715