CN210534819U - Miniature microscopic image acquisition device based on mobile phone - Google Patents
Miniature microscopic image acquisition device based on mobile phone Download PDFInfo
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- CN210534819U CN210534819U CN201921965361.4U CN201921965361U CN210534819U CN 210534819 U CN210534819 U CN 210534819U CN 201921965361 U CN201921965361 U CN 201921965361U CN 210534819 U CN210534819 U CN 210534819U
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Abstract
The utility model provides a miniature microscopic image collection system based on cell-phone, collection system include the support, are equipped with the cell-phone fixed station on the support, are equipped with the microscope camera lens below the camera of cell-phone, and the below of microscope camera lens is equipped with the slide seat, and the below of slide seat is equipped with light source, slide seat and microscope camera lens between be the scanning motion along X, Y axles, adopt the image of slide with the cell-phone, can reduce the volume by a wide margin, portable and promote by a wide margin have greatly reduced medical cost, make more remote medical institution also can use this technique to diagnose.
Description
Technical Field
The utility model relates to a medical image gathers the field, especially a miniature microscopic image acquisition device based on cell-phone.
Background
Cell and tissue slice scanning is an important data for disease diagnosis, scientific research and teaching, and the tissue slices in the glass slices are scanned by a digital tissue slice scanner and converted into digital images, so that the digital images are convenient to store, transmit and remotely diagnose, but the existing digital tissue slice scanner is very expensive, and each digital tissue slice scanner is about five hundred thousand yuan, such as the scheme described in Chinese patent document CN 107543792A, which limits the popularization of diagnosis, scientific research and teaching means of the tissue slices. In order to solve the technical problem, the prior art also adopts some improved schemes to reduce the equipment cost, and chinese patent document CN 106226897A describes a tissue slice scanning device based on a common optical microscope and a smart phone, which is composed of a microscope fixing frame, a common optical microscope, a smart phone, a focusing and slice moving device, a smart phone fixing frame and a computer. The functions of a smart phone, a computer and a microscope are integrated together, and the tissue section is digitized in a low-cost and convenient mode. But the structure is still large in size, inconvenient to move and high in price. And the optical path is longer, which affects the collection precision of the pattern.
SUMMERY OF THE UTILITY MODEL
The utility model aims to solve the technical problem that a miniature microscopic image collection system based on cell-phone is provided, reduce cost by a wide margin reduces the volume, and can realize miniature microscopic image automatic scanning collection.
In order to solve the technical problem, the utility model discloses the technical scheme who adopts is: a micro-microscopic image acquisition device based on a mobile phone comprises a support, wherein a mobile phone fixing table is arranged on the support and used for fixing the mobile phone;
a microscope lens is arranged below a camera of the mobile phone, a slide seat is arranged below the microscope lens, and an illumination light source is arranged below the slide seat;
the slide seat and the microscope lens do scanning movement along an X, Y axis so that the image of the slide is collected in the mobile phone.
In a preferred scheme, the microscope lens comprises a cantilever rod arranged on a mobile phone fixing table, one end of the cantilever rod is fixedly connected with the mobile phone fixing table, the other end of the cantilever rod is provided with a microscope lens, and the microscope lens is positioned below a camera of the mobile phone.
In a preferred scheme, a sunken step is arranged near a camera of the mobile phone on the mobile phone fixing table, and the cantilever rod is fixedly connected with the sunken step through a screw.
In the preferred scheme, at least one positioning pin is arranged on the sunken step, a corresponding pin hole is formed in the end of the cantilever rod, the positioning pin is connected with the pin hole in a sliding mode, the screw is in threaded connection with the cantilever rod, the end of the screw abuts against the sunken step, and the distance between the cantilever rod and the sunken step is adjusted through rotation of the screw.
In a preferred scheme, the microscope slide is a replaceable microscope lens;
the magnification of the micro lens is 2-10 times.
In the preferred scheme, positioning blocks are arranged on two sides of a mobile phone fixing table and are connected with the mobile phone fixing table through fixing screws;
the opposite surfaces of the two positioning blocks are inclined planes, the tops of the positioning blocks are wide, and the bottoms of the positioning blocks are narrow, so that the mobile phone can be locked by the inclined planes.
In the preferred scheme, a magnetic suction block is arranged on the surface of the mobile phone fixing table;
or at least one side of the machine fixing table is provided with a positioning block, and the surface of the mobile phone fixing table is provided with a magnetic suction block;
or at least one side of the machine fixing table is provided with a positioning block, and the surface of the mobile phone fixing table is provided with a silica gel friction plate.
In a preferred scheme, the slide seat is arranged on a scanning mechanism which runs along an X, Y shaft;
an X-axis guide rail is fixedly arranged on the support, an X-axis sliding block is slidably arranged on the X-axis guide rail, an X-axis driving nut is fixedly arranged on the X-axis sliding block, an X-axis driving motor is connected with an X-axis screw rod, and the X-axis screw rod is in threaded connection with the X-axis driving nut, so that the X-axis driving motor drives the X-axis sliding block to reciprocate along the X-axis guide rail;
and a Y-axis guide rail is fixedly arranged on the X-axis sliding block, a slide seat is slidably arranged on the Y-axis guide rail, a Y-axis drive nut is arranged on the slide seat, a Y-axis drive motor is connected with a Y-axis screw rod, and the Y-axis screw rod is in threaded connection with the Y-axis drive nut, so that the Y-axis drive motor drives the slide seat to reciprocate along the Y-axis guide rail.
In the preferred scheme, a control box is further arranged, and the control box outputs a switch signal to be connected with the mobile phone so as to control the mobile phone to take a picture;
the control box respectively outputs pulse signals to be connected with the X-axis driving motor and the Y-axis driving motor so as to respectively drive the X-axis driving motor and the Y-axis driving motor to rotate.
In a preferred scheme, the X-axis driving motor and the Y-axis driving motor are stepping motors;
the lighting source is an LED power supply.
The utility model provides a pair of miniature microscopic image collection system based on cell-phone can reduce the price of digital tissue slice scanner among the prior art by a wide margin, has greatly reduced medical cost, through the structure of the microscope head that adopts cantilever structure, can reduce the volume by a wide margin, portable and promote by a wide margin, have not only improved the efficiency that detects, have still reduced the sample detection to regional requirement, make more remote medical institutions also can use this technique to diagnose.
Drawings
The invention will be further explained with reference to the following figures and examples:
fig. 1 is a schematic perspective view of the present invention.
Fig. 2 is a schematic view of another direction of the three-dimensional structure of the present invention.
Fig. 3 is a schematic view of the three-dimensional structure of the mobile phone of the present invention.
Fig. 4 is a schematic perspective view of the mobile phone of the present invention in another direction.
Fig. 5 is a schematic structural view of the slide holder driving mechanism of the present invention.
Fig. 6 is a schematic structural view of the mobile phone fixing station of the present invention.
Fig. 7 is a schematic structural view of a fixed mobile phone preferred by the mobile phone fixing station of the present invention.
Fig. 8 is a schematic structural diagram of a medium microscope lens according to the present invention.
Fig. 9 is a control schematic diagram of the control box of the present invention.
In the figure: the microscope comprises a mobile phone fixing table 1, a positioning block 2, a microscope lens 3, a replaceable microscope lens 31, a cantilever rod 32, a support 4, a slide seat 5, a slide first stop 51, a slide second stop 52, a Y-axis drive nut 53, a Y-axis screw 54, a Y-axis drive motor 6, a slide 7, an illumination light source 8, a control box 9, an X-axis drive motor 10, an X-axis screw 101, an X-axis slide block 102, an X-axis drive nut 103, a Y-axis guide rail 104, an X-axis guide rail 105, a positioning pin 106, a screw 107, a sunken step 108, a mobile phone 11, a fixing screw 12 and a magnetic suction block 13.
Detailed Description
As shown in fig. 1 to 4, a micro microscopic image acquisition device based on a mobile phone comprises a support 4, wherein a mobile phone fixing table 1 is arranged on the support 4 and used for fixing a mobile phone 11.
A microscope lens 3 is arranged below a camera of the mobile phone 11, a slide seat 5 is arranged below the microscope lens 3, and an illumination light source 8 is arranged below the slide seat 5, preferably, the illumination light source 8 is an LED power supply. With the structure, when the cell phone is used, the light of the illumination light source 8 passes through the slide glass on the slide glass seat 5, and the image of the cell is transmitted to the camera of the cell phone through the micro lens 3, so that the cell phone is collected and stored by the camera of the cell phone.
As shown in fig. 3 to 5, the slide holder 5 and the microscope lens 3 perform a scanning motion along the X, Y axis, so that the image of the slide 7 is captured in the mobile phone 11.
In a preferred embodiment, as shown in fig. 8, the microlens 3 includes a cantilever bar 32 mounted on the mobile phone fixing platform 1, the cantilever bar 32 is in a shape that is bent from one side of the mobile phone fixing platform 1 to the direction of the camera, one end of the cantilever bar 32 is fixedly connected with the mobile phone fixing platform 1, and the other end is provided with a microlens, in the preferred embodiment, the magnification of the microscope is 2-10 times; further preferably, the magnifying power of the microscope lens is 4 times, and the microscope lens is located below the camera of the mobile phone 11. The utility model discloses replace the complicated light path structure of microscope among the prior art with a piece of microscope head 3 to further the cost is reduced has reduced the volume, and the definition of image further improves moreover.
Preferably, as shown in fig. 2 and 8, a sunken step 108 is provided near the camera of the mobile phone 11 on the mobile phone fixing stand 1, and the cantilever bar 32 is fixedly connected to the sunken step 108 by a screw 107. With this structure, the installation and connection of the microlens 3 are facilitated.
Preferably, as shown in fig. 8, a sunken step 108 is arranged near the camera of the mobile phone 11 on the mobile phone fixing platform 1, the sunken step 108 is provided with at least one positioning pin 106, the end of the cantilever rod 32 is provided with a corresponding pin hole, the positioning pin 106 is slidably connected with the pin hole, the screw 107 is in threaded connection with the cantilever rod 32, the end of the screw 107 abuts against the sunken step 108, and the distance between the cantilever rod 32 and the sunken step 108 is adjusted by the rotation of the screw 107, so as to adjust the distance between the microscope lens 31 and the camera of the mobile phone 11; it is further preferable that another screw for fixing is further provided, the screw is threaded through the cantilever bar 32 and is connected with the sunken step 108, and the screw is fastened after being adjusted to a proper position.
In a preferred embodiment, the micro lens is a replaceable micro lens 31. The replaceable microscope lens 31 is movably sleeved with the cantilever rod 32, so that the magnification adjustment can be realized conveniently by replacing the microscope lens.
In the preferred scheme as shown in fig. 3, 4 and 6, positioning blocks 2 are arranged on two sides of a mobile phone fixing table 1, and the positioning blocks 2 are connected with the mobile phone fixing table 1 through fixing screws 12;
the opposite surfaces of the two positioning blocks 2 are inclined planes, the tops of the positioning blocks 2 are wider, and the bottoms of the positioning blocks 2 are narrower, so that the mobile phone 11 is locked by the inclined planes. With this structure, the mobile phone 11 can be conveniently fixed.
In a preferred scheme, as shown in fig. 7, a magnetic block 13 is arranged on the surface of the mobile phone fixing table 1; with the structure, the camera position can be adjusted conveniently according to the difference of the mobile phone 11, so that the camera of the mobile phone 11 can be aligned with the microscope lens of the microscope lens 3.
Or at least one side of the mobile phone fixing table 1 is provided with a positioning block 2, and the surface of the mobile phone fixing table 1 is provided with a magnetic suction block 13. With this structure, positioning and fixing of the cellular phone 11 are facilitated.
Or at least one side of the machine fixing table 1 is provided with a positioning block 2, and the surface of the mobile phone fixing table 1 is provided with a silica gel friction plate. With this structure, the friction force of the silica gel friction plate is used to facilitate the positioning and fixing of the mobile phone 11.
The preferred arrangement is as shown in figure 5, where the slide holder 5 is mounted on a scanning mechanism that runs along axis X, Y. With this configuration, the image of the slide is divided into a plurality of small images for photographing by the snake-like scanning movement of the slide holder 5, and then the images are combined into a panoramic image.
Preferably, as shown in fig. 5, an X-axis guide rail 105 is fixedly arranged on the support 4, the X-axis slider 102 is slidably mounted on the X-axis guide rail 105, an X-axis drive nut 103 is fixedly arranged on the X-axis slider 102, the X-axis drive motor 10 is connected with an X-axis screw 101, and the X-axis screw 101 is in threaded connection with the X-axis drive nut 103, so that the X-axis drive motor 10 drives the X-axis slider 102 to reciprocate along the X-axis guide rail 105;
a Y-axis guide rail 104 is fixedly arranged on the X-axis slide block 102, the slide holder 5 is slidably arranged on the Y-axis guide rail 104, a Y-axis drive nut 53 is fixedly arranged on the slide holder 5, the Y-axis drive motor 6 is connected with a Y-axis screw rod 54, and the Y-axis screw rod 54 is in threaded connection with the Y-axis drive nut 53, so that the Y-axis drive motor 6 drives the slide holder 5 to reciprocate along the Y-axis guide rail 104. With the above structure, the snake-like scanning movement of the slide holder 5 along the axis X, Y is achieved.
In a preferred scheme, the X-axis driving motor 10 and the Y-axis driving motor 6 are stepping motors;
in a preferred scheme, as shown in fig. 9, a control box 9 is further provided, and at least one pin of the control box 9 outputs a switch signal to be connected with a mobile phone 11 so as to control the mobile phone to take a picture; the control box 9 is also point-connected to the illumination source 8 so that backlight is provided by the illumination source 8 during shooting.
At least two pins of the control box 9 respectively output pulse signals which are respectively connected with the X-axis driving motor 10 and the Y-axis driving motor 6 so as to respectively drive the X-axis driving motor 10 and the Y-axis driving motor 6 to rotate. Preferably, the control box is controlled by a single chip microcomputer, such as an STM32F series single chip microcomputer of Italian semiconductor.
When the microscope is used, as shown in fig. 1 to 9, the mobile phone 11 is fixed on the mobile phone fixing table 1, a camera of the mobile phone 11 is aligned with the microscope lens 3, a sample slide is placed on the slide seat 5, trial shooting is performed, parameters of the mobile phone are adjusted according to the definition of an image, or the height position of the microscope lens 3 is adjusted. Since the connection position of the cantilever bar 32 and the handset fixing station 1 is outside the coverage of the handset 11, the height adjustment is easy, and the adjustment is convenient for adapting to handsets of different models. After the adjustment is completed, the mobile phone 11 is connected with the control box 9 through a signal line. The slide 7 is positioned on the slide mount 5 and the button of the control box 9 is activated and the illumination source 8 is illuminated.
The starting mode can be controlled through an app interface on the mobile phone. The control box 9 sends a switching signal to the mobile phone and the lighting source 8, and simultaneously the mobile phone takes a picture to obtain a picture, and the picture is stored by the mobile phone; the control box 9 sends a pulse signal to the driving motor of the X-axis driving motor 10, drives the X-axis driving motor 10 to rotate by a preset angle, so that the rotation of the X-axis screw 101 drives the X-axis driving nut 103 to move for a distance, and the corresponding X-axis sliding block 102 moves for a distance, so that the slide holder 5 moves for a distance along the X-axis, the control box 9 sends a switch signal to the mobile phone and the lighting source 8, the lighting source 8 is lightened, and meanwhile, the mobile phone takes a picture to obtain a picture; and completing the photographing of a line of pictures on the slide until the slide seat 5 moves a preset stroke along the X axis. The control box 9 sends a pulse signal to the Y-axis driving motor 6 to drive the Y-axis driving motor 6 to rotate by a preset angle, so that the rotation of the Y-axis screw 54 drives the Y-axis driving nut 53 to move for a certain distance, the slide seat 5 moves for a certain distance along the Y axis, and the control box 9 controls the mobile phone to take a picture; then the control box 9 drives the slide seat 5 to walk for a preset stroke along the X axis again, the image of the slide 7 is scanned into the mobile phone in a snake-shaped scanning mode, then the mobile phone sends the slide to the server through the network, the panoramic image of the slide is spliced at the server, and cells in the panoramic image are classified, identified and marked in an artificial intelligence mode so as to be convenient for a doctor to diagnose, thus the collection and auxiliary diagnosis work of the slide image is completed, and the diagnosis efficiency of the doctor is greatly improved.
The above embodiments are merely preferred technical solutions of the present invention, and should not be considered as limitations of the present invention, and the features in the embodiments and the examples in the present application may be arbitrarily combined with each other without conflict. The protection scope of the present invention shall be defined by the claims and the technical solutions described in the claims, including the technical features of the equivalent alternatives as the protection scope. Namely, equivalent alterations and modifications within the scope of the invention are also within the scope of the invention.
Claims (10)
1. The utility model provides a miniature microscopic image acquisition device based on cell-phone, includes support (4), characterized by: the support (4) is provided with a mobile phone fixing table (1) for fixing a mobile phone (11);
a microscope lens (3) is arranged below a camera of the mobile phone (11), a slide seat (5) is arranged below the microscope lens (3), and an illumination light source (8) is arranged below the slide seat (5);
the slide seat (5) and the microscope lens (3) perform scanning movement along an X, Y axis so that the image of the slide (7) is collected in the mobile phone (11).
2. The miniature microscopic image acquisition device based on the mobile phone as set forth in claim 1, wherein: the microscope lens (3) comprises a cantilever rod (32) arranged on a mobile phone fixing platform (1), one end of the cantilever rod (32) is fixedly connected with the mobile phone fixing platform (1), the other end of the cantilever rod is provided with a microscope lens, and the microscope lens is positioned below a camera of the mobile phone (11).
3. The micro-image acquisition device based on the mobile phone as claimed in claim 2, wherein: a sunken step (108) is arranged near a camera of the mobile phone (11) on the mobile phone fixing table (1), and the cantilever rod (32) is fixedly connected with the sunken step (108) through a screw (107).
4. The micro-image acquisition device based on the mobile phone as claimed in claim 3, wherein: the sinking step (108) is provided with at least one positioning pin (106), the end of the cantilever rod (32) is provided with a corresponding pin hole, the positioning pin (106) is in sliding connection with the pin hole, the screw (107) is in threaded connection with the cantilever rod (32), the end of the screw (107) is propped against the sinking step (108), and the distance between the cantilever rod (32) and the sinking step (108) is adjusted through the rotation of the screw (107).
5. The micro-image acquisition device based on the mobile phone as claimed in claim 2, wherein: the micro lens is a replaceable micro lens (31);
the magnification of the micro lens is 2-10 times.
6. The miniature microscopic image acquisition device based on the mobile phone as set forth in claim 1, wherein: positioning blocks (2) are arranged on two sides of the mobile phone fixing table (1), and the positioning blocks (2) are connected with the mobile phone fixing table (1) through fixing screws (12);
the opposite surfaces of the two positioning blocks (2) are inclined planes, the tops of the positioning blocks (2) are wider, and the bottoms of the positioning blocks (2) are narrower, so that the mobile phone (11) can be locked by the inclined planes.
7. The miniature microscopic image acquisition device based on the mobile phone as set forth in claim 1, wherein: a magnetic suction block (13) is arranged on the surface of the mobile phone fixed table (1);
or a positioning block (2) is arranged on at least one side of the machine fixing table (1), and a magnetic suction block (13) is arranged on the surface of the mobile phone fixing table (1);
or at least one side of the machine fixing table (1) is provided with a positioning block (2), and the surface of the mobile phone fixing table (1) is provided with a silica gel friction plate.
8. The miniature microscopic image acquisition device based on the mobile phone as set forth in claim 1, wherein: the slide seat (5) is arranged on a scanning mechanism which runs along an X, Y shaft;
an X-axis guide rail (105) is fixedly arranged on the support (4), an X-axis sliding block (102) is slidably arranged on the X-axis guide rail (105), an X-axis driving nut (103) is fixedly arranged on the X-axis sliding block (102), an X-axis driving motor (10) is connected with an X-axis screw rod (101), and the X-axis screw rod (101) is in threaded connection with the X-axis driving nut (103) so that the X-axis driving motor (10) drives the X-axis sliding block (102) to reciprocate along the X-axis guide rail (105);
a Y-axis guide rail (104) is fixedly arranged on an X-axis sliding block (102), a slide seat (5) is slidably mounted on the Y-axis guide rail (104), a Y-axis driving nut (53) is arranged on the slide seat (5), a Y-axis driving motor (6) is connected with a Y-axis screw (54), and the Y-axis screw (54) is in threaded connection with the Y-axis driving nut (53) so that the Y-axis driving motor (6) drives the slide seat (5) to reciprocate along the Y-axis guide rail (104).
9. The miniature microscopic image acquisition device based on the mobile phone as set forth in claim 8, wherein: the mobile phone is also provided with a control box (9), and the control box (9) outputs a switch signal to be connected with the mobile phone (11) so as to control the mobile phone to take a picture;
the control box (9) respectively outputs pulse signals to be connected with the X-axis driving motor (10) and the Y-axis driving motor (6) so as to respectively drive the X-axis driving motor (10) and the Y-axis driving motor (6) to rotate.
10. The miniature microscopic image acquisition device based on the mobile phone as set forth in claim 8, wherein: the X-axis driving motor (10) and the Y-axis driving motor (6) are stepping motors;
the lighting source (8) is an LED power supply.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201921965361.4U CN210534819U (en) | 2019-11-14 | 2019-11-14 | Miniature microscopic image acquisition device based on mobile phone |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201921965361.4U CN210534819U (en) | 2019-11-14 | 2019-11-14 | Miniature microscopic image acquisition device based on mobile phone |
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| CN210534819U true CN210534819U (en) | 2020-05-15 |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110879999A (en) * | 2019-11-14 | 2020-03-13 | 武汉兰丁医学高科技有限公司 | Micro microscopic image acquisition device based on mobile phone and image splicing and identifying method |
| CN113589515A (en) * | 2021-08-19 | 2021-11-02 | 绍兴格物光学有限公司 | Portable microscope observation set |
| CN113589508A (en) * | 2021-08-19 | 2021-11-02 | 绍兴格物光学有限公司 | Image acquisition method based on portable microscope |
-
2019
- 2019-11-14 CN CN201921965361.4U patent/CN210534819U/en active Active
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110879999A (en) * | 2019-11-14 | 2020-03-13 | 武汉兰丁医学高科技有限公司 | Micro microscopic image acquisition device based on mobile phone and image splicing and identifying method |
| US11586028B2 (en) | 2019-11-14 | 2023-02-21 | Wuhan Landing Intelligence Medical Co., Ltd. | Mobile phone-based miniature microscopic image acquisition device and image stitching and recognition methods |
| CN113589515A (en) * | 2021-08-19 | 2021-11-02 | 绍兴格物光学有限公司 | Portable microscope observation set |
| CN113589508A (en) * | 2021-08-19 | 2021-11-02 | 绍兴格物光学有限公司 | Image acquisition method based on portable microscope |
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Address after: 430000 B7, C and D units, one or two floors, medical equipment Park, 818 hi tech Avenue, East Lake New Technology Development Zone, Hubei, Wuhan, Patentee after: Wuhan Lanting intelligent Medicine Co.,Ltd. Address before: 430073 floor 1 and 2, unit B, C and D, building B7, medical equipment Park, No. 818, Gaoxin Avenue, Donghu New Technology Development Zone, Wuhan City, Hubei Province Patentee before: WUHAN LANDING MEDICAL HI-TECH Ltd. |