CN210530641U - Pass-through box subassembly - Google Patents

Pass-through box subassembly Download PDF

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Publication number
CN210530641U
CN210530641U CN201920223066.5U CN201920223066U CN210530641U CN 210530641 U CN210530641 U CN 210530641U CN 201920223066 U CN201920223066 U CN 201920223066U CN 210530641 U CN210530641 U CN 210530641U
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liquid
liquid conveying
transfer
box body
pipe
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CN201920223066.5U
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Chinese (zh)
Inventor
李壮林
梁纯刚
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Rongchang Biopharmaceutical Yantai Co Ltd
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Rongchang Biopharmaceutical Yantai Co Ltd
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Abstract

The utility model belongs to the pharmaceutical production equipment field relates to a pass-through box subassembly, including the box, the transmission mouth, first hatch door, second hatch door and transmission connecting piece. The beneficial effects of the utility model reside in that, can realize the continuous transmission of liquid material between the isolation room of different clean degrees through box and transmission connecting piece, can also effectively prevent cross infection, and easy to assemble, dismantlement, repeatedly usable has saved the transmission cost.

Description

Pass-through box subassembly
Technical Field
The utility model relates to a pharmaceutical production technical field especially relates to a pass-through box subassembly.
Background
The transfer window is an important device for transferring articles in a laboratory, is usually arranged on a room partition wall, and has the main function of preventing polluted airflow from being transmitted along with the transfer of materials and reducing the pollution of a clean area.
When the materials are transferred from the non-sterile area B to the sterile area or the clean area A, the cabin door above the transfer window is generally set to be an electronic or mechanical interlocking structure, so that only one door can be opened at the same time to prevent cross infection. However, in the conventional transfer window, the hatch door needs to be opened first and then closed, the fan in the hatch is self-cleaned, and the hatch is operated to be opened after a set value is reached, so that articles can be transmitted from the non-sterile area B. The transfer window can only transfer intermittently, and can not transfer articles continuously, especially the continuous sterile transfer of liquid materials.
In the pharmaceutical production process, the aseptic transmission of liquid materials between two isolated areas with different cleanliness levels is often required, the device for transmitting the aseptic liquid medicine in the domestic biopharmaceutical field mainly comprises a stainless steel pipeline and an aseptic filter, but the stainless steel pipeline is fixedly arranged between chambers with different cleanliness levels, the liquid medicine of different batches needs to be comprehensively cleaned and sterilized in the pharmaceutical process, and the operation is complex; and there is a risk of cross-contamination due to material residue. Therefore, it is preferable to select a transfer tube having good sealing property for transfer. The sterilization filter needs to exhaust before liquid filtration, and the exhaust before the filter element is required to be discharged in a bacteria area and is forbidden to be discharged in a sterile area in the preparation of medicines. And in order to avoid cross contamination between the two isolation regions, no cavity or gap can be formed between the two isolation regions when liquid is required to be transmitted, and mutual flowing of air in the two isolation regions is avoided.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to provide a pass-through box subassembly can make the liquid material avoid cross contamination by non-sterile chamber or low toilet to sterile chamber or high clean room transmission in-process, and easy to assemble, dismantlement, repeatedly usable.
In order to achieve the above main object, the present invention provides a delivery window assembly, which comprises a box body, wherein a first door and a second door are installed on the box body; there is the transmission mouth on the first hatch door, its characterized in that: the transfer window assembly further comprises a transfer connecting piece matched with the box body for use, wherein the transfer connecting piece comprises a first liquid conveying pipe, a transfer port box body inner side quick connecting piece and a second liquid conveying pipe, the transfer port box body inner side quick connecting piece comprises a liquid conveying connecting pipe and a blocking cover for blocking the inner side end of the transfer port box body, and the liquid conveying connecting pipe penetrates through the blocking cover to play a role in connecting the first liquid conveying pipe and the second liquid conveying pipe; first liquid delivery pipe lug connection communicate behind the liquid delivery connecting pipe one end of the inboard quick connector of transfer port box or the connection one or more degerming filters the liquid delivery connecting pipe one end of the inboard quick connector of transfer port box, the liquid delivery connecting pipe other end lug connection second liquid delivery pipe of the inboard quick connector of transfer port box or connect behind one or more degerming filters intercommunication second liquid delivery pipe.
Further, the connection between the pipes is matched and connected through a connecting piece.
Further, the first liquid conveying pipe and/or the second liquid conveying pipe are hoses or the preparation material of the pipes is a material with certain elasticity.
Furthermore, one end or two ends of the transfer port are provided with detachable sealing covers which are used for realizing the sealing of the transfer port when liquid is not transferred.
Further, the box body further comprises a sterilizing device.
Further, the sterilizing device comprises a fan and a filter and is used for realizing filtration sterilization of the isolation cabin.
Further, the sterilization device comprises a hydrogen peroxide generator for realizing fumigation sterilization of the isolation cabin.
Further, the enclosure contains an electrical or mechanical interlock such that the first door and the second door cannot both open at the same time.
Further, the utility model discloses still include one kind be arranged in with above arbitrary the supporting transmission connecting piece that uses of box, its characterized in that: the transmission connecting piece includes first liquid conveying pipe, and second liquid conveying pipe and is arranged in any one above the shutoff transmission mouth box medial extremity just plays the inboard quick-witted piece of transmission mouth box of first liquid conveying pipe of intercommunication and second liquid conveying pipe, the inboard quick-witted piece of transmission mouth box includes the shutoff lid of liquid conveying connecting pipe and shutoff transmission mouth box medial extremity, the liquid conveying connecting pipe link up the shutoff lid plays the effect of connecting first liquid conveying pipe and second liquid conveying pipe.
Further, the transfer link further comprises one or more sterilizing filters.
Furthermore, the quick connector on the inner side of the transfer port box body comprises a liquid conveying connecting pipe and a blocking cover for blocking the inner side end of the transfer port box body, and the liquid conveying connecting pipe penetrates through the blocking cover to play a role in connecting the first liquid conveying pipe with the second liquid conveying pipe.
Further, one or both ends of the pipe are provided with a connector facilitating quick connection of the two pipes.
Further, the tube is a hose or the tube is made of a material having a certain elasticity.
The utility model has the advantages of it is following:
compared with the prior art, the beneficial effects of the utility model reside in that: the utility model discloses a pass-through box subassembly when realizing the transmission of liquid material, forms the liquid material pass-through box subassembly that the leakproofness is good, can also effectively prevent the cross infection between the different clean grade regions, and easy to assemble, dismantlement, can used repeatedly, saved the transmission cost.
Drawings
The present invention will be further explained with reference to the accompanying drawings:
FIG. 1 is a schematic structural view of the box body of the present invention;
fig. 2 is a schematic structural view of a transmission connector of the present invention;
fig. 3 is an exploded view of a transmission connector according to the present invention;
fig. 4 is a schematic view of the installation of the transmission connector in embodiment 1 of the present invention;
fig. 5 is a schematic structural diagram of a first step in installing a transmission connector on a box body in embodiment 1 of the present invention;
fig. 6 is a schematic structural diagram of a second step when the transmission connecting piece is installed on the box body in embodiment 1 of the present invention;
fig. 7 is a schematic view of the installation of a transmission connector according to embodiment 2 of the present invention;
fig. 8 is a schematic structural diagram of a first step in installing a transmission connector in a box body in embodiment 2 of the present invention;
fig. 9 is a schematic structural diagram of a second step when the transmission connecting piece is installed on the box body in embodiment 2 of the present invention;
in the figure, 1-box; 2-a first door; 3-a second door; 4-a transfer port; 5-a transmission connection; 6-a first liquid delivery pipe; 7-quick connecting piece at inner side of the box body of the transfer port; 8-a second liquid delivery pipe; 9-liquid delivery connection pipe; 10-blocking cover; 11-one end of the liquid conveying connecting pipe; 12-the other end of the liquid delivery connection tube; 13-sterilizing filter; 14-removable containment caps; 15-a sterilization device; 16-a fan; 17-a filter; 18-hydrogen peroxide generator.
Detailed Description
Example 1
As shown in fig. 1, 4, 5 and 6, a transfer window assembly includes a box body 1, the box body 1 is located between two isolation areas, in this embodiment, the left side of the box body is a sterile area a, and the right side is a non-sterile area B. The box body 1 is provided with a first cabin door 2 and a second cabin door 3, the first cabin door 2 is provided with a transfer port 4, wherein the transfer port 4 is respectively provided with an opening at the inner side and the outer side of the box body 1, and each opening is provided with a detachable plugging cover 14 which is matched with each other, and the first cabin door and the second cabin door are connected through a hoop in the embodiment; a sterilizing device 15 is further provided on the cabinet to achieve self-cleaning of sterilization inside the cabinet, and in this embodiment, the sterilizing device 15 is provided as a combination of a fan 16, a filter 17, and a hydrogen peroxide generator 18. The transfer window assembly further comprises a transmission connecting piece 5 matched with the box body 1 for use so as to realize transmission of liquid materials, wherein the transmission connecting piece 5 comprises a first liquid conveying pipe 6, a transfer port box body inner side quick connecting piece 7, a second liquid conveying pipe 8 and a sterilizing filter 13, in the embodiment, the first liquid conveying pipe 6 and the second liquid conveying pipe 8 are both arranged to be hoses, the transfer port box body inner side quick connecting piece 7 is composed of a liquid conveying connecting pipe 9 and a blocking cover 10 for closing the transfer port box body inner side, the liquid conveying connecting pipe 9 penetrates through the blocking cover 10 of the transfer port box body inner side to play a role in connecting the first liquid conveying pipe 6 and the second liquid conveying pipe 8, and the first liquid conveying pipe 6 is matched with one end 11 of the liquid conveying connecting pipe 9; the two ends of the sterilizing filter 13 are respectively provided with a connecting piece, one end of the sterilizing filter is matched with the other side end 12 of the liquid conveying connecting pipe 9, and the other end of the sterilizing filter 13 is matched with the second liquid conveying pipe 8.
When the transfer window does not transfer liquid materials: as shown in fig. 1 and 3, the detachable blocking covers 14 at both ends of the transfer port 4 are in a closed state, and the first hatch 2, the second hatch 3, the fan 16 and the filter 17 are all in a closed state; while the transfer link 5 does not need to be assembled.
When the liquid material is transferred through the transfer window: firstly, after a liquid outlet of a first liquid conveying pipe 6 in a transmission connecting piece 5 is closed, putting all components of the transmission connecting piece 5 into a sterilization cabinet for sterilization, connecting the components in a sterile area A after sterilization according to a graph 4, then opening a first cabin door 2, putting the sterilized transmission connecting piece 5 into a box body 1, then as shown in the graph 4, detaching a detachable sealing cover 14 at the inner side end of the box body of a transfer port 4, putting the first liquid conveying pipe 6 in the transmission connecting piece 5 into the transfer port, closing an opening at the inner side end of the box body of the transfer port 4 by a sealing cover 10 connected with the transmission connecting piece 5, closing the first cabin door 2, detaching the detachable sealing cover 14 at the outer side end of the box body of the transfer port 4, and taking out the first liquid conveying pipe 6; as shown in fig. 5, the second door 3 is opened, the second liquid conveying pipe 8 is taken out and connected with the liquid delivery device in the area B, and the first liquid conveying pipe 6 is connected with the liquid delivery device or the liquid conveying pipe in the sterile area a by a disposable sterile connector or a sterile pipeline welding machine to convey liquid materials.
When the liquid material is conveyed: after disconnecting the first liquid supply tube 6 from the liquid delivery means in zone a, it is inserted into the delivery opening 4 and the opening to the left of the delivery opening 4 is closed with a removable closure cap 14. And (3) detaching the blocking cover 10 from the transfer port 4 from the area B, taking the transmission connecting piece 5 out of the second cabin door 3, closing the second cabin door 3, and then opening the fan 16, the filter 17 and the hydrogen peroxide generator 18 to realize the self-cleaning of the box body.
Example 2
As shown in fig. 1 and fig. 7-9, a transfer window assembly includes a box body 1, the box body 1 is located between two isolation areas, in this embodiment, the left side of the box body is a non-sterile area B, and the right side is a sterile area a. The box body 1 is provided with a first cabin door 2 and a second cabin door 3, the first cabin door 2 is provided with a transfer port 4, wherein the transfer port 4 is respectively provided with an opening at the inner side and the outer side of the box body 1, and each opening is provided with a detachable plugging cover 14 which is matched with each other, and the first cabin door and the second cabin door are connected through screw threads in the embodiment; a degerming device 15 is further provided on the cabinet to achieve self-cleaning of the interior of the cabinet, and in this embodiment, the degerming device 15 is provided with a fan 16 and a filter 17. The transfer window assembly further comprises a transmission connecting piece 5 which is matched with the box body 1 for use so as to realize the transmission of the liquid materials, wherein the transmission connecting piece 5 comprises a first liquid conveying pipe 6, a transfer port box body inner side quick connecting piece 7, a second liquid conveying pipe 8 and a sterilizing filter 13, the first liquid conveying pipe 6 and the second liquid conveying pipe 8 are both made of elastic silica gel materials, the quick connector 7 at the inner side of the box body of the transfer port is composed of a liquid conveying connecting pipe 9 and a blocking cover 10 for closing the inner side of the box body of the transfer port, wherein the liquid transport connecting pipe 9 link up the inboard shutoff lid 10 of transfer port box and play the effect of connecting first liquid delivery pipe 6 and second liquid delivery pipe 8, first liquid delivery pipe 6 connect behind a degerming filter 13 with the 11 looks adaptations of one end of liquid transport connecting pipe 9, second liquid delivery pipe 8 and the 12 looks adaptations of the other end of liquid transport connecting pipe 9.
When the transfer window does not transfer liquid materials: as shown in fig. 1 and 3, the detachable blocking covers 14 at both ends of the transfer port 4 are in a closed state, and the first hatch 2, the second hatch 3, the fan 16 and the filter 17 are all in a closed state; while the transfer link 5 does not need to be assembled.
When the liquid material is transferred through the transfer window: firstly, after a liquid outlet of a second liquid conveying pipe 8 in a transmission connecting piece 5 is sealed, all components of the transmission connecting piece 5 are placed into a sterilization cabinet for sterilization, the components are connected in a sterile area A according to a graph 7 after sterilization, then the second cabin door 3 is opened to place the transmission connecting piece 5 after sterilization into a box body 1, a detachable sealing cover 14 at the inner side end of the box body of a transmission port 4 is detached, a first liquid conveying pipe 6 and a sterile filter part in the transmission connecting piece 5 are placed into the transmission port, an opening at the inner side of the box body of the transmission port 4 is sealed by a sealing cover 10 on the transmission connecting piece 5, and then the second cabin door 3 is closed. As shown in fig. 8 again, the detachable plugging cover 14 at the outer side end of the box body of the transfer port 4 is detached, the first liquid conveying pipe 6 is taken out to be connected to the liquid output device in the area B, the sterilizing filter 13 is left in the transfer port or taken out along with the first liquid conveying pipe 6, as shown in fig. 9 again, the second cabin door 3 is opened, the second liquid conveying pipe 8 is taken out, and the second liquid conveying pipe is connected with the liquid input device or the liquid conveying pipe in the sterile area a through a disposable sterile connector or a sterile pipeline welding machine to transmit liquid materials.
When the liquid material is conveyed: after the second fluid-carrying duct 8 has been removed from the fluid delivery means in zone a, it is retracted into the box 1 and the second hatch 3 is closed. The first cabin door 2 is opened, the blocking cover 10 is detached from the transfer port 4, then the openings at two sides of the transfer port 4 are closed by the detachable blocking cover 14, the transmission connecting piece 5 is taken out from the first cabin door 2, the first cabin door 2 is closed, and then the fan 16 and the filter 17 are opened to realize the self-cleaning of the box body.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not intended to limit the present invention in any way, so that any person skilled in the art can make modifications or changes to the present invention by using the above disclosed technical contents. However, any simple modification, equivalent change and modification made to the above embodiments according to the technical substance of the present invention still belong to the protection scope of the technical solution of the present invention.

Claims (15)

1. A delivery window assembly comprises a box body (1), wherein a first cabin door (2) and a second cabin door (3) are installed on the box body (1); there is transfer mouth (4) on first hatch door (2), its characterized in that: the transfer window assembly further comprises a transmission connecting piece (5) matched with the box body (1) for use, the transmission connecting piece (5) comprises a first liquid conveying pipe (6), a transfer port box body inner side quick connecting piece (7) and a second liquid conveying pipe (8), the transfer port box body inner side quick connecting piece (7) comprises a liquid conveying connecting pipe (9) and a blocking cover (10) for blocking the inner side end of the transfer port box body, and the liquid conveying connecting pipe (9) penetrates through the blocking cover (10); first liquid delivery pipe (6) lug connection communicate behind liquid transport connecting pipe (9) one end (11) or the connection one or more degerming filter (13) of the inboard quick-witted part of transfer port box (7) liquid transport connecting pipe (9) one end (11) of the quick-witted part of transfer port box (7), communicate second liquid delivery pipe (8) behind liquid transport connecting pipe (9) other end (12) the lug connection second liquid delivery pipe (8) or the connection one or more degerming filter (13) of the inboard quick-witted part of transfer port box (7).
2. The delivery window assembly of claim 1, wherein: the pipes are connected in a matching way through connecting pieces.
3. The delivery window assembly of claim 2, wherein: the first liquid conveying pipe (6) and/or the second liquid conveying pipe (8) are hoses or the preparation material of the pipes is a material with certain elasticity.
4. The delivery window assembly of claim 3, wherein: one end or two ends of the transfer port (4) are also provided with detachable sealing covers (14) which are used for realizing the sealing of the transfer port when liquid is not transferred.
5. The delivery window assembly of claim 4, wherein: the box further comprises a sterilizing device (15).
6. The delivery window assembly of claim 5, wherein: the sterilizing device (15) comprises a fan (16) and a filter (17).
7. The delivery window assembly of claim 6, wherein: the sterilization apparatus (15) includes a hydrogen peroxide generator (18).
8. The delivery window assembly of any of claims 1-7, wherein: the box further comprises an electronic or mechanical interlock such that the first door (2) and the second door (3) cannot both be opened simultaneously.
9. A transmission connection for use with a housing (1) in a pass-through window assembly as claimed in any one of claims 1 to 8, characterised in that: the transmission connecting piece (5) comprises a first liquid conveying pipe (6), a second liquid conveying pipe (8) and a transmission port box inner side quick connecting piece (7) used for plugging the inner side end of the transmission port box body in any one of claims 1 to 8 and used for communicating the first liquid conveying pipe (6) with the second liquid conveying pipe (8), the transmission port box inner side quick connecting piece (7) comprises a liquid conveying connecting pipe (9) and a plugging cover (10) used for plugging the inner side end of the transmission port box body, and the liquid conveying connecting pipe (9) penetrates through the plugging cover (10).
10. The transfer link of claim 9, wherein: the transfer connection further comprises one or more sterilizing filters (13).
11. The transfer link of claim 9 or 10, wherein: one or both ends of the tube are provided with a connector facilitating quick connection of the two tubes.
12. The transfer link of claim 9 or 10, wherein: the tube is a hose or the tube is made of a material with certain elasticity.
13. A transfer port box inside quick connect for use in the transfer window assembly of any one of claims 1-8, wherein: the quick connector (7) at the inner side of the transfer port box body comprises a liquid conveying connecting pipe (9) and a blocking cover (10) for blocking the inner side end of the transfer port box body in claims 1-8, wherein the liquid conveying connecting pipe (9) penetrates through the blocking cover (10).
14. The transfer port box interior quick connect of claim 13, wherein: one or both ends of the tube are provided with a connector facilitating quick connection of the two tubes.
15. The transfer port box interior quick connect of claim 13, wherein: the tube is a hose or the tube is made of a material with certain elasticity.
CN201920223066.5U 2019-02-22 2019-02-22 Pass-through box subassembly Active CN210530641U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201920223066.5U CN210530641U (en) 2019-02-22 2019-02-22 Pass-through box subassembly

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201920223066.5U CN210530641U (en) 2019-02-22 2019-02-22 Pass-through box subassembly

Publications (1)

Publication Number Publication Date
CN210530641U true CN210530641U (en) 2020-05-15

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109914987A (en) * 2019-02-22 2019-06-21 荣昌生物制药(烟台)有限公司 A kind of transmitting window assembly

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109914987A (en) * 2019-02-22 2019-06-21 荣昌生物制药(烟台)有限公司 A kind of transmitting window assembly

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