CN210495944U

CN210495944U - Cell is a filtration membrane section of thick bamboo for film-making

Info

Publication number: CN210495944U
Application number: CN201920969347.5U
Authority: CN
Inventors: 刘召宏; 李茹
Original assignee: Nanjing Jumper Jinyuan Medical Instrument Co ltd
Current assignee: Nanjing Jumper Jinyuan Medical Instrument Co ltd
Priority date: 2019-06-25
Filing date: 2019-06-25
Publication date: 2020-05-12
Anticipated expiration: 2029-06-25

Abstract

The utility model relates to a filtration membrane section of thick bamboo for cell film-making, including lower membrane section of thick bamboo, with lower membrane section of thick bamboo joint complex goes up the membrane section of thick bamboo and locates go up membrane section of thick bamboo and diaphragm between the lower membrane section of thick bamboo, it is equipped with the negative pressure mouth to go up membrane section of thick bamboo top, lower membrane bobbin base portion be equipped with the filtration pore is crossed that the negative pressure mouth is linked together, the utility model discloses can with a mode of taking out the negative pressure will treat that filterable cell liquid ration is sent into a filtration membrane section of thick bamboo and is carried out filterable filtration membrane section of thick bamboo, have and use manpower sparingly, improve.

Description

Cell is a filtration membrane section of thick bamboo for film-making

Technical Field

The utility model belongs to the technical field of liquid-based thin-layer cell film-making technology and specifically relates to a cell is a filtration membrane section of thick bamboo for film-making.

Background

At present, in medical biological assay, liquid-based thin-layer cytology slides are often required to be manufactured for microscopic observation, and most of the existing slide-making equipment transfers cells on a filter membrane onto a slide glass through a negative pressure membrane filtration technology.

The existing method for filtering cell sap requires that an upper membrane cylinder and a lower membrane cylinder of a filtering membrane cylinder are manually separated, then the cell sap to be separated in a reagent bottle is poured into a measuring device for quantification, and then is poured into the filtering membrane cylinder for filtering.

The above prior art solutions have the following drawbacks: when the cell sap to be filtered is filtered, the process of pouring the cell sap to be filtered by holding the reagent bottle by a technician consumes time and labor and has lower working efficiency.

SUMMERY OF THE UTILITY MODEL

The utility model aims at providing a filtration membrane section of thick bamboo for cell film-making, this filtration membrane section of thick bamboo can be with the mode of taking out the negative pressure will treat filterable cell liquid from the reagent bottle quick suction filtration membrane section of thick bamboo in, need not manual operation, have the effect of using manpower sparingly, improvement work efficiency.

The above utility model discloses an above-mentioned utility model purpose can realize through following technical scheme:

the utility model provides a filtration membrane section of thick bamboo for cell film-making, including a lower membrane section of thick bamboo, with lower membrane section of thick bamboo joint complex goes up a membrane section of thick bamboo and locates go up a membrane section of thick bamboo and the diaphragm between the lower membrane section of thick bamboo, it is equipped with the negative pressure mouth to go up membrane section of thick bamboo top, lower membrane bobbin base portion be equipped with the filtration pore that the negative pressure mouth is linked together.

By adopting the technical scheme, the upper membrane cylinder and the lower membrane cylinder are clamped to realize easy separation, so that the membrane is convenient to replace; the negative pressure mouth links to each other with the reagent bottle, and filtration membrane bobbin bottom is connected with negative pressure device, through the negative pressure effect with the cell liquid quick suction in the reagent bottle in the filtration membrane bobbin, the cell liquid passes through the diaphragm through the negative pressure mouth, and cytoplasm in the cell liquid is attached to stay on the diaphragm, and the cell liquid after the filtration flows through the filtration pore again, need not pass through manual separation cell liquid, uses manpower sparingly promptly, has improved work efficiency.

The utility model discloses further set up to: lower diaphragm capsule includes lower stack shell, seals stationary blade and the concentric ring on lower stack shell top are established the protruding eaves of stationary blade upper surface, the diaphragm laminating the stationary blade upper surface just is arranged in the protruding eaves, stationary blade enclose and close and form the slot, it is in the slot to filter the hole evenly distributed.

By adopting the technical scheme, the slot is used for being matched with and clamped with the upper film cylinder to realize clamping of the upper film cylinder and the lower film cylinder; the diameter of protruding eaves is the same with the diameter of diaphragm, and the diaphragm laminating of being convenient for is placed, and a filtration membrane section of thick bamboo removes the in-process, and the diaphragm is difficult for rocking.

The utility model discloses further set up to: go up the membrane section of thick bamboo including last stack shell, locate go up the baffle at stack shell inner wall middle part and locate the baffle lower surface with the first inserted sheet of slot grafting complex, the baffle divide into drum and lower drum with last stack shell, negative pressure mouth protrusion sets up baffle upper surface center department, the cavity that runs through from top to bottom is equipped with along its length direction to the negative pressure mouth, be equipped with the through-hole on the baffle, the cavity with the through-hole is linked together.

By adopting the technical scheme, during filtering, cell sap to be filtered in the reagent bottle can pass through the through hole through the hollow cavity and be filtered by the membrane; first inserted sheet can be pegged graft with the slot and cooperate, realizes the joint of drum and lower membrane section of thick bamboo down.

The utility model discloses further set up to: the wall thickness of the bottom end of the lower cylinder is thinner than that of the cylinder body.

Through adopting above-mentioned technical scheme, the diameter of lower drum is greater than the diameter of lower drum, and during the grafting, light simple and convenient can realize down that drum and lower membrane section of thick bamboo are swift to be pegged graft.

The utility model discloses further set up to: the outer wall of the upper film cylinder surrounds the partition plate and is provided with a first annular plate in an extending mode, and the first annular plate is perpendicular to the cylinder body of the upper film cylinder.

By adopting the technical scheme, the first annular plate is convenient for holding the upper film cylinder by hand and has a certain anti-skid function; in addition, the first ring plate facilitates the balancing of the upper membrane cartridge.

The utility model discloses further set up to: the cross section of the negative pressure nozzle is triangular, and the end, far away from the partition plate, of the negative pressure nozzle is a pointed end.

Through adopting above-mentioned technical scheme, the negative pressure mouth is kept away from baffle one end is established to the pointed end, and the technician is laborsaving swiftly inserts the negative pressure mouth in the reagent bottle.

The utility model discloses further set up to: the cross section of the lower film cylinder is trapezoidal, and the diameter of the bottom end of the lower film cylinder is larger than that of the top end of the lower film cylinder.

Through adopting above-mentioned technical scheme, a membrane section of thick bamboo cross section is established to trapezoidal, is convenient for its top and the cooperation of last membrane section of thick bamboo joint, goes up the insertible type height of cooperation of a membrane section of thick bamboo and lower membrane section of thick bamboo.

The utility model discloses further set up to: the bottom of the lower film barrel is provided with a basin-shaped base, the interior of the basin-shaped base is communicated with the lower film barrel, the top of the basin-shaped base extends around the outer wall of the basin-shaped base to form a second annular plate, and the second annular plate is parallel to the first annular plate.

By adopting the technical scheme, the basin-shaped base is convenient for stably placing the filtering membrane cylinder; the membrane section of thick bamboo and lower membrane section of thick bamboo are gone up in the cooperation dismouting of second crown plate and first crown plate, and it is more convenient to peg graft to the staff accessible.

To sum up, the utility model discloses a beneficial technological effect does:

1. the liquid taking is efficient: when the cell sap is filtered, the cell sap to be separated does not need to be extruded quantitatively by manpower, so that the labor is saved, and the working efficiency is improved;

2. high degree of cooperation: the end part of the negative pressure nozzle is a tip, so that the negative pressure nozzle is easy to be inserted into a reagent bottle in a matching way; the upper film cylinder and the lower film cylinder are simple in connection mode and are not easy to slip off; the flange of the inner wall of the bottom of the lower membrane cylinder is matched with the negative pressure device for fixing;

3. the structure is stable: the bottom of the lower film cylinder is provided with a basin-shaped base which is stable to place; the outer walls of the upper film cylinder and the lower film cylinder are provided with a first annular plate and a second annular plate, so that the balance of the upper film cylinder and the lower film cylinder is kept conveniently.

Drawings

Fig. 1 is a schematic view of the overall structure of the present invention.

FIG. 2 is a schematic sectional view of the upper membrane cartridge.

Fig. 3 is a schematic structural view of the lower membrane cartridge.

In the figure: 1. a film feeding cylinder; 10. a filtration pore; 11. a lower cylinder body; 12. a fixing sheet; 2. a membrane cylinder is arranged; 21. an upper barrel body; 22. a partition plate; 220. a through hole; 23. an upper cylinder; 24. a lower cylinder; 3. a membrane; 4. a negative pressure nozzle; 40. a cavity; 5. a convex brim; 6. a slot; 7. a filter disc; 13. a first tab; 14. a ring member; 15. a first ring plate; 16. a basin-shaped base; 17. a second ring plate.

Detailed Description

The present invention will be described in further detail with reference to the accompanying drawings.

Example (b):

referring to fig. 1, in order to the utility model discloses a filtration membrane cartridge for cell slide, which comprises a lower membrane cartridge 1, an upper membrane cartridge 2 clamped above the lower membrane cartridge 1 and a membrane 3 arranged between the upper membrane cartridge 2 and the lower membrane cartridge 1, wherein the top of the upper membrane cartridge 2 is provided with a negative pressure nozzle 4, the negative pressure nozzle 4 is communicated with a reagent bottle filled with cell liquid to be filtered, a filtration hole 10 is arranged below the negative pressure nozzle 4, and the filtration hole 10 is arranged in the lower membrane cartridge 1; cell sap flows into the lower membrane cylinder 1 through the negative pressure nozzle 4 and is filtered through the filtering holes 10; go up a membrane section of

thick bamboo

2, 1 joint of a lower membrane section of thick bamboo, this mode realizes going up a membrane section of

thick bamboo

2 and 3 easy isolations of a lower membrane section of thick bamboo, is convenient for change diaphragm 3.

Referring to fig. 2 and fig. 1, the upper membrane cylinder 2 includes an upper cylinder body 21, a partition plate 22 horizontally arranged around the inner wall of the upper cylinder body, and a first insert 13 arranged on the lower surface of the partition plate 22, the partition plate 22 is arranged in the middle of the upper membrane cylinder 2, the partition plate 22 divides the upper cylinder body 21 into an upper cylinder 23 and a lower cylinder 24, the bottom end wall thickness of the lower cylinder 24 is thinner than the cylinder wall thickness, the negative pressure nozzle 4 is arranged in the upper cylinder 23 and protrudes out of the upper surface of the partition plate 22, the negative pressure nozzle 4 is provided with a cavity 40 penetrating up and down along the length direction thereof, the cross section of the negative pressure nozzle 4 is triangular, one end of the negative pressure nozzle 4 away from the partition plate 22 is set to be a tip, the partition plate 22 is provided with a through hole 220 (not shown in the figure), the through hole 220 is communicated with the cavity; during filtering, cell sap to be filtered enters the cavity 40, flows through the through holes 220, enters the lower cylinder 24 and finally enters the lower membrane cylinder 1 to realize filtering; the upper film cylinder 2 and the lower film cylinder 1 are spliced through a first inserting piece 13; the diameter of the bottom end of the lower cylinder 24 is larger than that of the upper part of the cylinder body, so that the lower cylinder 24 can be quickly inserted into the lower membrane cylinder 1; the tip of the negative pressure nozzle 4 is convenient for a technician to insert the negative pressure nozzle 4 into the reagent bottle quickly and effortlessly, the first ring plate 15 is convenient for the hand to hold the upper membrane cylinder 2, and the first ring plate has a certain balance effect on the upper membrane cylinder 2.

Referring to fig. 3, the lower membrane cylinder 1 comprises a lower cylinder body 11, a fixing plate 12 for closing the top end of the lower cylinder body 11 and a convex brim 5 concentrically arranged on the fixing plate 12 with the lower cylinder body 11, the membrane 3 (see fig. 1) is attached to the upper surface of the fixing plate 12 and is arranged in the convex brim 5, the convex brim 5 and the fixing plate 12 are enclosed to form a slot 6 matched with the first insertion sheet 13, and the filtering holes 10 are uniformly distributed in the slot 6; cell sap to be filtered passes through the membrane 3, cytoplasm in the cell sap is attached to the surface of the membrane 3, and other substances flow into the lower cylinder body 11 through the filtering holes 10; the diameter of the convex eaves 5 is the same as that of the membrane 3, the membrane 3 is attached to the inner wall of the convex eaves 5, the stability of the membrane 3 is facilitated, and the membrane 3 is not prone to falling off when the filtering membrane cylinder is opened; the slot 6 is in plug fit with the first plug-in sheet 13 (see fig. 2) to realize the clamping connection of the upper film cylinder 2 (see fig. 2) and the lower film cylinder 1.

Referring to fig. 3 and 2, the side section of the lower cylinder body 11 is trapezoidal, the diameter of the bottom end of the lower cylinder body 11 is larger than that of the top end of the lower cylinder body 11, a basin-shaped base 16 is arranged at the bottom of the lower membrane cylinder 1, the interior of the basin-shaped base 16 is communicated with the lower cylinder body 11, a second annular plate 17 extends around the outer wall of the basin-shaped base 16, and the second annular plate 17 is parallel to the first annular plate 15; the lower cylinder body 11 and the upper film cylinder 2 are conveniently clamped and matched and are tightly clamped; the basin-shaped base 16 is convenient for stably placing the filtering membrane cylinder and increasing the balance of the filtering membrane cylinder; the second ring plate 17 can be used as a hand-held piece, so that the lower barrel body 11 and the upper membrane barrel 2 can be conveniently disassembled and assembled.

The implementation principle of the embodiment is as follows: before cell sap is filtered, a reagent bottle filled with cell sap to be filtered is inserted and communicated with a negative pressure nozzle 4 arranged on an upper membrane cylinder 2, a basin-shaped base 16 is connected with a device for generating negative pressure to absorb the cell sap to be filtered, when the negative pressure is generated in a filtering membrane cylinder, the cell sap in the reagent bottle enters the negative pressure nozzle 4 under the action of pressure, the cell sap flows into a cylinder body through a cavity 40 and passes through a membrane 3, cytoplasm in the cell sap is attached to the surface of the membrane 3, and other substances flow to a lower cylinder body 11 through a filtering hole 10.

The embodiment of this specific implementation mode is the preferred embodiment of the present invention, not limit according to this the utility model discloses a protection scope, so: all equivalent changes made according to the structure, shape and principle of the utility model are covered within the protection scope of the utility model.

Claims

1. A filtration membrane cartridge for cell slide preparation, characterized in that: including a lower membrane section of thick bamboo (1), with lower membrane section of thick bamboo (1) joint complex go up membrane section of thick bamboo (2) and locate go up membrane section of thick bamboo (2) and lower membrane section of thick bamboo diaphragm (3) between (1), it is equipped with negative pressure mouth (4) to go up membrane section of thick bamboo (2) top, lower membrane section of thick bamboo (1) bottom be equipped with filtration pore (10) that negative pressure mouth (4) are linked together.

2. A filtration membrane cartridge for cell preparation according to claim 1, wherein: lower membrane section of thick bamboo (1) is established including lower stack shell (11), closure stationary blade (12) and concentric ring on stack shell (11) top down protruding eaves (5) of stationary blade (12) upper surface, laminating in diaphragm (3) stationary blade (12) upper surface just is arranged in protruding eaves (5), stationary blade (12) enclose and close and form slot (6), cross filtration hole (10) evenly distributed in slot (6).

3. A filtration membrane cartridge for cell preparation according to claim 2, wherein: go up membrane section of thick bamboo (2) including stack shell (21), locate go up baffle (22) at stack shell (21) inner wall middle part and locate baffle (22) lower surface with slot (6) are pegged graft first inserted sheet (13) of complex, baffle (22) divide into drum (23) and lower drum (24) with last stack shell (21), negative pressure mouth (4) protrusion sets up baffle (22) upper surface center department, cavity (40) that run through about negative pressure mouth (4) are equipped with along its length direction, be equipped with through-hole (220) on baffle (22), cavity (40) with through-hole (220) are linked together.

4. A filtration membrane cartridge for cell preparation according to claim 3, wherein: the wall thickness of the bottom end of the lower cylinder (24) is thinner than that of the cylinder body.

5. A filtration membrane cartridge for cell preparation according to claim 4, wherein: go up membrane section of thick bamboo (2) outer wall and encircle baffle (22) extend and be equipped with first crown plate (15), first crown plate (15) perpendicular go up membrane section of thick bamboo (2) stack shell.

6. A filtration membrane cartridge for cell preparation according to claim 3, wherein: the cross section of the negative pressure nozzle (4) is triangular, and one end, far away from the partition plate (22), of the negative pressure nozzle (4) is a tip.

7. A filtration membrane cartridge for cell preparation according to claim 2, wherein: the cross section of the lower film cylinder (1) is trapezoidal, and the diameter of the bottom end of the lower film cylinder (1) is larger than that of the top end of the lower film cylinder (1).

8. A filtration membrane cartridge for cell preparation according to claim 5, wherein: lower membrane section of thick bamboo (1) bottom is equipped with basin shape base (16), in the basin shape base (16) with lower membrane section of thick bamboo (1) is linked together, basin shape base (16) top is encircleed its outer wall and is extended and be equipped with second crown plate (17), second crown plate (17) with first crown plate (15) are parallel.