CN210479416U - Endotoxin detection kit - Google Patents

Abstract

The utility model discloses an endotoxin detection kit, which comprises a box body, a plurality of placing racks, a bottle opening mechanism and a push plate, wherein the placing racks, the bottle opening mechanism and the push plate are arranged in the box body; the placing rack is provided with a plurality of bottle body placing cavities for storing ampoule bottles, the bottoms of the bottle body placing cavities are provided with through holes, the surfaces of the push plates are provided with a plurality of convex columns which are in one-to-one correspondence with the positions of the through holes, and the convex columns can be inserted into the through holes and extend into the bottle body placing cavities; bottle opening mechanism is including opening the bottle cover, and it deposits the chamber to open the bottle cover and be equipped with and place the bottle head that the chamber position corresponds with the body, and the bottle head is deposited chamber upper portion and is connected with arched rubber cap, and rubber cap upper surface is connected with the clamp plate, and the lower surface is connected with the compression leg, and it is equipped with the cutting knife to open the bottle cover below, and the cutting knife is connected with its control assembly who opens and shuts of control. The utility model discloses can open a plurality of ampoule simultaneously, the simple operation does not need artifical bare-handed ampoule to break off with the fingers and thumb, and the security is high, has reduced the risk that reagent pollutes, and ampoule bottle head and body are abandoned and are collected the convenience.

Description

Endotoxin detection kit

Technical Field

The utility model belongs to the technical field of biological detection kit, concretely relates to endotoxin detect reagent box.

Background

The examination of bacterial endotoxin as prescribed in the Chinese pharmacopoeia, 2015 edition, includes two methods, namely a gel method and a photometric method, the latter including a turbidity method and a chromogenic matrix method. The gel method is a method for qualitatively or semi-quantitatively detecting endotoxin by the principle of agglutination reaction between limulus reagent and endotoxin.

The laboratory generally purchases a kit for detecting endotoxin, wherein the standard substance, limulus reagent and endotoxin in the kit are stored in a multi-purpose ampoule bottle for endotoxin detection. When endotoxin is detected by using the corresponding kit, particularly when a plurality of samples need to be detected simultaneously, researchers need to break a plurality of ampoule bottles by bare hands, and the risk of scratching fingers and polluting reagents is extremely high. The prior ampoule bottle opening device is mostly used for opening a single ampoule bottle, so that medical staff can conveniently open medical injection to avoid cutting injury, only the bottle body is left for convenient follow-up operation, the problem that how to quickly discard the bottle head left in an opener and the used bottle body into a sharps box is not considered, and the bottle head in the opener is easy to roll down everywhere to cause personal injury.

SUMMERY OF THE UTILITY MODEL

An object of the utility model is to overcome not enough among the prior art, provide an endotoxin detect reagent box, solved and opened a plurality of ampoule and wasted time and energy, the security is low simultaneously, current opening device is unfavorable for the problem that bottle head and body collected.

The utility model provides a following technical scheme:

an endotoxin detection kit comprises a kit body, and a plurality of placing frames, a bottle opening mechanism and a push plate which are arranged in the kit body;

the ampoule bottle placing rack is provided with a plurality of bottle body placing cavities for storing ampoule bottles, through holes are formed in the bottoms of the bottle body placing cavities, a plurality of protruding columns which are in one-to-one correspondence with the through holes are arranged on the surfaces of the push plates, and the protruding columns can be inserted into the through holes and extend into the bottle body placing cavities;

the bottle opening mechanism comprises a bottle opening cover, the bottle opening cover is provided with a bottle head storage cavity corresponding to the position of the bottle body placing cavity, the upper portion of the bottle head storage cavity is connected with an arched rubber cap, the upper surface of the rubber cap is connected with a pressing plate, the lower surface of the rubber cap is connected with a pressing column, a cutting knife is arranged below the bottle opening cover, and the cutting knife is connected with a control assembly for controlling the opening and closing of the cutting knife.

Preferably, the cutting knife comprises two symmetrically arranged blades, and a semicircular knife groove corresponding to the bottle head storage cavity is arranged on each blade.

Preferably, the blade is provided with a long-strip-shaped limiting hole perpendicular to the length direction of the blade, the bottom of the bottle opening cover is provided with a limiting column penetrating through the limiting hole, and the bottom end of the limiting column is connected with a limiting block with a width larger than the width of the limiting hole.

Preferably, the control assembly includes that one end is fixed in the spring of uncork both sides, the connecting block that links to each other with the spring other end and locates the connecting rod between connecting block and the blade, the both sides of blade all are equipped with first pivot, be equipped with the second pivot on the connecting block, the both ends of connecting rod are overlapped respectively and are formed to rotate in first pivot and second pivot and connect, the connecting block outside is equipped with the pull rod, the pull rod end is equipped with the handle.

Preferably, a vertical shaft is arranged between the pressing plate and the connecting block, the centers of two sides of the pressing plate are respectively provided with an upper transverse shaft, the connecting block is provided with a lower transverse shaft corresponding to the upper transverse shaft, and two ends of the vertical shaft are respectively sleeved on the upper transverse shaft and the lower transverse shaft to form rotary connection.

Preferably, the bottom in chamber is placed to the body is equipped with the protection and fills up, and the inner wall lower part is equipped with a plurality of body fixed blocks of arranging along the circumferencial direction, the inner wall upper portion in chamber is deposited to the bottle head is equipped with a plurality of bottle head fixed blocks of arranging along the circumferencial direction, the cross sectional shape of body fixed block and bottle head fixed block is the arc.

Preferably, the edge of the push plate is provided with a frame capable of being clamped on the periphery of the placing frame.

Preferably, the box body further comprises a tray arranged in the box body.

Preferably, the box body is hinged with the box cover through a hinge, a foam block is arranged in the box body, and a cavity for accommodating the placing rack, the bottle opening mechanism, the push plate and the tray is formed in the foam block.

Compared with the prior art, the beneficial effects of the utility model are that:

(1) the utility model discloses place the ampoule that is equipped with endotoxin detection reagent in the body of rack and place the intracavity, when needing to start the ampoule simultaneously, insert the bottle head of ampoule and deposit the chamber of opening the bottle head of bottle cover, control the cutting knife through the control assembly and press from both sides the bottle head tightly, the experimenter holds and opens the bottle cover, exerts a little external force and can cut the bottle head down, the simple operation does not need artifical bare-handed breaking off the ampoule, and the security is high, has also reduced the risk of reagent pollution;

(2) the utility model is provided with the pressing plate, when the bottle head is cut off, the pressing plate is pressed downwards, the rubber cap moves downwards, and the pressing column presses a plurality of bottle heads out of the bottle head storage cavity simultaneously; after reagent finishes using in the ampoule, insert the through-hole that the chamber bottom was placed to the body with the projection of clamp plate, can release a plurality of bodies simultaneously, the collection of ampoule bottle head and body of being convenient for.

Drawings

Fig. 1 is a schematic top view of the present invention;

fig. 2 is a front view of the internal structure of the rack;

FIG. 3 is a schematic view of the top view of the rack with no ampoule installed;

FIG. 4 is a schematic top view of a push plate;

FIG. 5 is a front view of the push plate;

FIG. 6 is a front view of the internal structure of the bottle opening mechanism;

FIG. 7 is a schematic view of a portion of the structure of FIG. 6;

FIG. 8 is a schematic view of the cutting blade and control assembly with no external force applied by the spring;

FIG. 9 is a schematic view of the cutting blade and control assembly with the spring slightly compressed;

FIG. 10 is a schematic view of the cutting blade and control assembly with the spring compressed;

FIG. 11 is a schematic top view of the platen;

FIG. 12 is a schematic right side view of the vertical shaft, the pressure plate and the connecting block of FIG. 6;

FIG. 13 is a schematic diagram of the position structure of the push plate, the placing rack and the tray when being used in cooperation;

labeled as: 1. a box body; 2. a box cover; 3. placing a rack; 31. a bottle body placing cavity; 32. a bottle body fixing block; 33. a protective pad; 34. a through hole; 4. an ampoule bottle; 5. a bottle opening mechanism; 6. pressing a plate; 61. an upper horizontal axis; 7. opening the bottle cover; 71. a bottle head storage cavity; 72. a rubber cap; 73. a limiting block; 74. pressing the column; 75. a bottle head fixing block; 76. a limiting column; 8. a cutting knife; 81. a first blade; 82. a second blade; 83. a cutter groove; 84. a limiting hole; 85. a first rotating shaft; 9. pushing the plate; 91. a frame; 92. a convex column; 10. a tray; 11. a foam block; 12. a handle; 13. a vertical axis; 14. connecting blocks; 141. a second rotating shaft; 142. a lower horizontal axis; 15. a pull rod; 16. a spring; 17. a connecting rod; 18. an ampoule bottle body; 19. and (7) a hinge.

Detailed Description

The present invention will be further described with reference to the accompanying drawings. The following examples are only for illustrating the technical solutions of the present invention more clearly, and the protection scope of the present invention is not limited thereby.

It should be noted that, in the description of the present invention, the terms "front", "rear", "left", "right", "upper", "lower", "inner", "outer", etc. indicate the directions or positional relationships based on the directions or positional relationships shown in the drawings, and are only for convenience of description of the present invention but do not require the present invention to be constructed and operated in a specific direction, and thus, should not be construed as limiting the present invention. As used in the description of the present invention, the terms "front," "back," "left," "right," "up," "down" and "in" refer to directions in the drawings, and the terms "inner" and "outer" refer to directions toward and away from, respectively, the geometric center of a particular component.

As shown in fig. 1-7, an endotoxin detection kit comprises a box body 1, and a plurality of placing frames 3, a bottle opening mechanism 5, a push plate 9 and a tray 10 which are arranged in the box body 1; the rack 3 is provided with a plurality of body placing cavities 31 for storing the ampoule bottles 4, a plurality of standard products, limulus reagents and endotoxin detection water are filled in the ampoule bottles, the bottoms of the body placing cavities 31 are provided with through holes 34, the surface of the push plate 9 is provided with a plurality of silica gel material convex columns 92 which are in one-to-one correspondence with the through holes 34, the convex columns 92 can be inserted into the through holes 34 and extend into the body placing cavities 31, and the edge of the push plate 9 is provided with a frame 91 which can be clamped on the periphery of the rack 3; bottle opening mechanism 5 is including bottle opening cover 7, and bottle opening cover 7 is equipped with and places the bottle head that chamber 31 position corresponds with the body and deposit chamber 71, and the bottle head is deposited chamber 71 upper portion and is connected with arched rubber cap 72, and rubber cap 72 upper surface is connected with clamp plate 6, and the lower surface is connected with compression leg 74, and bottle opening cover 7 below is equipped with cutting knife 8, and cutting knife 8 is connected with the control assembly who controls its opening and shutting.

As shown in fig. 7-10, the cutting knife 8 includes a first blade 81 and a second blade 82 symmetrically disposed, and the blades are provided with semicircular knife grooves 83 corresponding to the positions of the bottle head storage cavities 71, when the first blade 81 and the second blade 82 are combined, the two semicircular knife grooves 83 are combined into a circular knife groove with a diameter smaller than the diameter of the opening of the ampoule bottle. Be equipped with the spacing hole 84 with the mutually vertically rectangular shape of blade length direction on the blade, uncork cover 7 bottom is equipped with the spacing post 76 that passes spacing hole 84, and spacing post 76 bottom is connected with the stopper 73 that the width is greater than spacing hole 84 width, and when the blade removed, spacing post 76 was located the different positions in spacing hole 84 for it is spacing to cut the cutting knife 8, improved cutting knife 8's structural stability.

As shown in fig. 7-10, the control assembly includes a spring 16 having one end fixed to both sides of the bottle opener 7, a connecting block 14 connected to the other end of the spring 16, and a connecting rod 17 disposed between the connecting block 14 and the blades (81, 82), wherein both sides of the blades (81, 82) are provided with first rotating shafts 85, the connecting block 14 is provided with second rotating shafts 141, both ends of the connecting rod 17 are respectively sleeved on the first rotating shafts 85 and the second rotating shafts 141 to form a rotating connection, a pull rod 15 is disposed outside the connecting block 14, and a handle 12 is disposed at the end of the pull rod 15.

As shown in fig. 11-12, a vertical shaft 13 is disposed between the pressing plate 6 and the connecting block 14, an upper horizontal shaft 61 is disposed at the center of each side of the pressing plate 6, a lower horizontal shaft 142 corresponding to the upper horizontal shaft 61 is disposed on the connecting block 14, and two ends of the vertical shaft 13 are respectively sleeved on the upper horizontal shaft 61 and the lower horizontal shaft 142 to form a rotary connection.

As shown in fig. 2, 3, 6, and 7, the bottom of the body placing cavity 31 is provided with a protective pad 33 made of a silica gel material, so as to prevent the bottom of the ampoule bottle from being damaged, the lower portion of the inner wall is provided with a plurality of body fixing blocks 32 arranged along the circumferential direction, so as to fix the ampoule bottle body, the upper portion of the inner wall of the head storing cavity 71 is provided with a plurality of head fixing blocks 75 arranged along the circumferential direction, so as to fix the head of the ampoule bottle, both the body fixing blocks 32 and the head fixing blocks 75 are made of silica gel material, and the cross section of each body fixing block and each head fixing block 75 are arc-shaped.

As shown in figure 1, a box body 1 is hinged with a box cover 2 through a hinge 19, a foam block 11 is arranged in the box body 2, the foam block 11 is provided with a cavity for accommodating a placing frame 3, a bottle opening mechanism 5, a push plate 9 and a tray 10, and the foam block 11 can protect all parts from being damaged in transportation.

The utility model discloses a use-way does: when endotoxin detection is required, the box cover 2 is opened, all parts are taken out of the box body 1, the bottle opening mechanism 5 is arranged above the placing frame 3, as shown in fig. 8, the spring 16 has no external force, and the first blade 81 and the second blade 82 are in a combined state; as shown in fig. 9, the handle 12 is held to slightly push the connecting block 14 inwards, the spring 16 is slightly compressed, the first blade 81 and the second blade 82 are slightly separated, the lower end of the vertical shaft 13 moves inwards along with the connecting block 14, the pressing plate 6 slightly moves downwards, at this time, the pressing column 74 cannot enter the bottle head storage cavity 71 due to small movement amount, the bottle heads of all the ampoules are inserted into the bottle head storage cavity 71 of the bottle opening cover 7, then the handle 12 is released, the spring 16 and the control assembly recover to the state shown in fig. 8, the bottle heads are clamped by the first blade 81 and the second blade 82, and the experimenter holds the bottle opening cover 7 by hand and can cut off the bottle heads by applying a small external force; then the placing frame 3 is removed, the tray 10 is placed below the bottle opening mechanism 5, as shown in fig. 10, the handle 12 is held by hand to push the connecting block 14 inwards, at this time, the spring 16 is compressed, the connecting rod 17 drives the first blade 81 and the second blade 82 to separate, meanwhile, the lower end of the vertical shaft 13 moves inwards along with the connecting block 14, the pressing plate 6 moves downwards, and the pressing column 74 is driven to press the ampoule bottle head, so that the ampoule bottle head falls into the tray 10 below. As shown in fig. 13, after the reagent in the ampoule bottle is used, the placing rack 3 is inverted, the tray 10 is placed below the placing rack, the push plate 9 is clamped with the periphery of the placing rack 3 through the frame 91, at this time, the convex column 92 is inserted into the through hole 34, and continues to go deep into the bottle body placing cavity 31 to push out the ampoule bottle body 18, and then the ampoule bottle body falls into the tray 10 below the through hole.

The utility model can simultaneously open a plurality of ampoule bottles, is convenient to operate, does not need to manually break the ampoule bottles by hand, has high safety and reduces the risk of reagent pollution; the ampoule bottle head and the ampoule bottle body are convenient to collect.

The foregoing is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, a plurality of modifications and variations can be made without departing from the technical principle of the present invention, and these modifications and variations should also be considered as the protection scope of the present invention.

Claims (9)

1. An endotoxin detection kit is characterized by comprising a kit body, a plurality of placing frames, a bottle opening mechanism and a push plate, wherein the placing frames, the bottle opening mechanism and the push plate are arranged in the kit body;

the ampoule bottle placing rack is provided with a plurality of bottle body placing cavities for storing ampoule bottles, through holes are formed in the bottoms of the bottle body placing cavities, a plurality of protruding columns which are in one-to-one correspondence with the through holes are arranged on the surfaces of the push plates, and the protruding columns can be inserted into the through holes and extend into the bottle body placing cavities;

the bottle opening mechanism comprises a bottle opening cover, the bottle opening cover is provided with a bottle head storage cavity corresponding to the position of the bottle body placing cavity, the upper portion of the bottle head storage cavity is connected with an arched rubber cap, the upper surface of the rubber cap is connected with a pressing plate, the lower surface of the rubber cap is connected with a pressing column, a cutting knife is arranged below the bottle opening cover, and the cutting knife is connected with a control assembly for controlling the opening and closing of the cutting knife.

2. The endotoxin detection kit of claim 1, wherein the cutting knife comprises two symmetrically arranged blades, and the blades are provided with semicircular knife grooves corresponding to the positions of the bottle head storage cavities.

3. The endotoxin detection kit of claim 2, wherein the blade is provided with an elongated limiting hole perpendicular to the length direction of the blade, the bottom of the decapping cover is provided with a limiting post penetrating through the limiting hole, and the bottom end of the limiting post is connected with a limiting block with a width larger than the width of the limiting hole.

4. The endotoxin detection kit of claim 3, wherein the control assembly comprises a spring with one end fixed on both sides of the decapping cover, a connecting block connected with the other end of the spring, and a connecting rod arranged between the connecting block and the blade, wherein both sides of the blade are provided with a first rotating shaft, the connecting block is provided with a second rotating shaft, both ends of the connecting rod are respectively sleeved on the first rotating shaft and the second rotating shaft to form rotating connection, a pull rod is arranged outside the connecting block, and the tail end of the pull rod is provided with a handle.

5. The endotoxin detection kit of claim 4, wherein a vertical shaft is provided between the pressing plate and the connecting block, an upper horizontal shaft is provided at the center of each of the two sides of the pressing plate, a lower horizontal shaft corresponding to the upper horizontal shaft is provided on the connecting block, and the two ends of the vertical shaft are respectively sleeved on the upper horizontal shaft and the lower horizontal shaft to form a rotary connection.

6. The endotoxin detection kit of claim 1, wherein the bottom of the body accommodating chamber is provided with a protective pad, the lower part of the inner wall is provided with a plurality of body fixing blocks arranged along the circumferential direction, the upper part of the inner wall of the tip storage chamber is provided with a plurality of tip fixing blocks arranged along the circumferential direction, and the cross-sectional shapes of the body fixing blocks and the tip fixing blocks are both arc-shaped.

7. The endotoxin detection kit of claim 1, wherein the edge of the push plate is provided with a frame which can be clamped at the periphery of the placing frame.

8. The endotoxin detection kit of claim 1, further comprising a tray disposed within the cartridge body.

9. The endotoxin detection kit of claim 8, wherein the box body is hinged with the box cover through a hinge, a foam block is arranged in the box body, and the foam block is provided with a cavity for accommodating the placing frame, the decapping mechanism, the push plate and the tray.

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