CN210472621U

CN210472621U - Tablet processing mixing granulating tablet press

Info

Publication number: CN210472621U
Application number: CN201821560151.2U
Authority: CN
Inventors: 王献; 李玉生; 董宪武
Original assignee: YOUCARE PHARMACEUTICAL GROUP ANHUI NATURAL PHARMACEUTICAL CO Ltd
Current assignee: YOUCARE PHARMACEUTICAL GROUP ANHUI NATURAL PHARMACEUTICAL CO Ltd
Priority date: 2018-09-25
Filing date: 2018-09-25
Publication date: 2020-05-08
Anticipated expiration: 2028-09-25

Abstract

The utility model relates to a tablet processing mixing granulation tablet press, including a mixing granulation cylinder, a drying screen device, a tablet press and a tablet sieving machine, the top of the mixing granulation cylinder is provided with a feed inlet, an observation port and a liquid inlet system, the liquid inlet system comprises a horizontally arranged liquid inlet pipeline, and the liquid inlet pipeline is provided with a plurality of spraying ports; the bottom of the mixing and granulating cylinder is provided with a first stirring shaft, the first stirring shaft is provided with an arc-shaped mixing knife, and the side wall of the mixing cylinder is provided with a high-speed cutting knife and a granulating knife; the dry screen device comprises a double-layer screen, a heating pipe, a dust bin and a fine material discharge pipe, the double-layer screen comprises a large-hole screen on the upper layer and a small-hole screen on the lower layer, the heating pipe is arranged below and on the periphery of the double-layer screen, and the fine material discharge pipe is connected with the end part of the small-hole screen. Has the advantages that: when in tabletting, the material particles are uniformly stressed and have good fluidity, the compactness of the tablet is improved, and the quality of the tablet is high.

Description

Tablet processing mixing granulating tablet press

Technical Field

The utility model relates to a tablet processing technology field, concretely relates to tablet processing mixes pelletization tablet press.

Background

The tablet is a tablet preparation formed by uniformly mixing the medicine and the auxiliary materials and then pressing, and the appearance of the tablet is round and has the shape of an ellipse, a triangle and the like. There are two methods for producing tablets: powder tabletting method and granule tabletting method, wherein the granule tabletting method can adopt dry granulation and wet granulation.

Granulation is the operation of processing the material in the form of powder, melt, aqueous solution, etc. into granules having a certain shape and size. Granulation is an important process in the tablet processing process, and aims to: 1. improving the fluidity; 2. preventing the segregation of the ingredients; 3. preventing dust from flying and preventing the dust from adhering to the wall of the vessel; 4. adjusting the bulk density and improving the solubility; 5. improving the uniform transfer of pressure in the production of tablets, etc.

However, after the granulation process in the prior art, the technical purpose requirements are difficult to achieve, so that the phenomena of poor flowability, uneven stress and the like are frequently caused during tabletting.

SUMMERY OF THE UTILITY MODEL

In order to realize the above purpose, the utility model discloses a technical scheme be:

a tablet processing mixing granulating tablet press comprises a mixing granulating barrel, a drying screen device, a tablet press and a tablet sieving machine, wherein the mixing granulating barrel is connected with the drying screen device through a discharge pipeline, the drying screen device is connected with the feed end of the tablet press through a pipeline, the tablet press is connected with the tablet sieving machine through a pipeline, a feed inlet, an observation port and a liquid inlet system are arranged at the top of the mixing granulating barrel, the liquid inlet system comprises a horizontally arranged liquid inlet pipeline, and a plurality of spraying ports are arranged on the liquid inlet pipeline;

the bottom of the mixing and granulating barrel is provided with a first stirring shaft, the first stirring shaft is provided with an arc-shaped mixing knife, the side wall of the mixing barrel is provided with a high-speed cutting knife and a granulating knife, and the high-speed cutting knife and the granulating knife are positioned on two sides of the central axis of the mixing barrel;

the dry screen device comprises a double-layer screen, a heating pipe, a dust bin and a fine material discharge pipe, the double-layer screen comprises a large-hole screen on the upper layer and a small-hole screen on the lower layer, the heating pipe is arranged below and on the periphery of the double-layer screen, and the fine material discharge pipe is connected with the end part of the small-hole screen.

Further, the feed liquor system still includes humidity transducer, control system, water feeder and flow control valve, control system is through the electricity connection humidity transducer and the water feeder.

Further, the liquid inlet pipeline is a horizontal pipe or a circular pipe which is horizontally arranged.

Further, the granulating knife is positioned above the arc-shaped mixing knife, and the high-speed cutting knife is positioned above the horizontal plane where the granulating knife is positioned.

Further, the granulating knife consists of 4-6 groups of blades arranged in parallel with the side wall of the mixing granulating barrel.

Further, the aperture of the large-hole screen mesh is slightly larger than the particle size of the particles prepared by the mixing and granulating cylinder, and the aperture of the small-hole screen mesh is smaller than the particle size of the particles prepared by the mixing and granulating cylinder.

Further, sieve mascerating machine bottom is equipped with the dust and collects the storehouse, sieve mascerating machine lateral wall is equipped with and becomes piece tablet and collect the storehouse.

The technical effects of the utility model reside in that:

mix the high-speed cutting knife and the pelletization sword that set up on sword and the lateral wall through the arc of compounding pelletization bobbin base portion setting, accomplish the mixed pelletization of powder and liquid material in a compounding section of thick bamboo, it is more even to pelletize, the mixed pelletization time has been shortened, arrange the dry screen device of material to after the pelletization is accomplished, through heating pipe to granular material heat drying, double screen's setting can be with the pelletization inequality, materials such as adhesion and the even material separation of pelletization, make even material granule get into the tablet press and carry out the preforming, material granule atress is even during the preforming, the mobility is good, the compactness of tablet has been improved, the tablet quality is high.

Other features and advantages of the present invention will be described in detail in the detailed description which follows.

Drawings

Fig. 1 is a schematic structural diagram of the mixing and granulating tablet press of the present invention;

FIG. 2 is a schematic view of the mixing and granulating cylinder of the present invention

Fig. 3 is a schematic view of the drying screen device of the present invention.

Reference numerals: 1-mixing and granulating barrel; 11-a feed inlet; 12-a viewing port; 13-a first stirring shaft; 130-arc mixing knife; 14-high speed cutting knife; 15-granulating knife; 16-a liquid inlet system; 160-a liquid inlet pipeline; 1601-a spray port; 161-humidity sensor; 162-a control system; 163-water supply; 165-a flow control valve; 17-a discharge pipeline; 2-drying the screen device; 20-double layer screen mesh; 201-macroporous screen; 202-small hole screen; 21-heating a tube; 22-dust bin; 23-fine material discharge pipe; 3-tabletting machine; 31-a feed end; 4-screening machine; 41-dust collection bin; 42-tablet collection bin.

Detailed Description

The following detailed description of the embodiments of the present invention will be made with reference to the accompanying drawings. It is to be understood that the description of the embodiments herein is for purposes of illustration and explanation only and is not intended to limit the invention.

Referring to the attached drawings 1-3, a tablet processing mixing granulating tablet press comprises a mixing granulating barrel 1, a drying screen device 2, a tablet press 3 and a tablet sieving machine 4, wherein the mixing granulating barrel 1 is connected with the drying screen device 2 through a discharge pipeline 17, the drying screen device 2 is connected with a feed end 31 of the tablet press 3 through a pipeline, the tablet press 3 is connected with the tablet sieving machine 4 through a pipeline, a feed inlet 11, an observation port 12 and a liquid inlet system 16 are arranged at the top of the mixing granulating barrel 1, the liquid inlet system 16 comprises a liquid inlet pipeline 160 which is horizontally arranged, and a plurality of spraying ports 1601 are arranged on the liquid inlet pipeline 160;

the bottom of the mixing and granulating cylinder 1 is provided with a first stirring shaft 13, the first stirring shaft 13 is provided with an arc-shaped mixing knife 130, the side wall of the mixing cylinder 1 is provided with a high-speed cutting knife 14 and a granulating knife 15, and the high-speed cutting knife 14 and the granulating knife 15 are positioned on two sides of the central axis of the mixing cylinder 1;

drying screen device 2 includes double-deck screen cloth 20, heating pipe 21 and dust storehouse 22, double-deck screen cloth 20 includes the macropore screen cloth 201 on upper strata and the aperture screen cloth 202 of lower floor, heating pipe 21 sets up double-deck screen cloth 20's below and periphery.

The mixing and granulating of powder and liquid materials are completed in the mixing and granulating barrel through the arc-shaped mixing knife 130 arranged at the bottom of the mixing and granulating barrel 1 and the high-speed cutting knife 14 and the granulating knife 15 arranged on the side wall, so that the mixing and granulating time is shortened, the granulating is more uniform, the flowability of the materials is higher, the materials are discharged to the drying screen device 2 after the granulating is completed, the granular materials are heated and dried by the heating pipe 21, and the problem that tablets are difficult to eject during tabletting due to overhigh humidity of the granular materials is avoided; the large-hole screen 201 can separate the adhered and agglomerated granular materials on the upper layer of the large-hole screen 201, the small-hole screen 202 can sieve and collect the crushed granular materials, the fallen powder and the like into the dust bin 22 for recycling and mixing, the uniform material particles enter the tablet press 3 for tabletting after being sieved by the double-layer screen 20, the material particles are uniformly stressed and have good fluidity during tabletting, the compactness of the tablet is improved, and the quality of the tablet is high.

Further, the liquid inlet system 16 further includes a humidity sensor 161, a control system 162, a water supply 163 and a flow control valve 165, wherein the control system 162 is electrically connected to the humidity sensor 161 and the water supply 163. Detect the moisture content in the compounding pelletization section of thick bamboo 1 through humidity transducer 161, the inflow of rethread control system 161 control water feeder 163 accomplishes slow feed liquor, guarantees to mix the pelletization effect.

Further, the liquid inlet pipe 160 is a horizontal pipe or a circular pipe horizontally disposed. Ensure the uniform mixing of the powder and the liquid.

Further, the granulating knife 15 is located above the arc-shaped mixing knife 130, and the high-speed cutting knife 14 is located above the horizontal plane of the granulating knife 15. The blades arranged at different height positions can be used for fully mixing the materials in the mixing and granulating barrel 1, so that the mixing and granulating time is shortened, and the uniform granulating is ensured.

Further, the granulating knife 15 is composed of 4-6 groups of blades arranged in parallel with the side wall of the mixing granulating barrel 1.

Further, sieve 4 bottom is equipped with dust and collects storehouse 41, sieve 4 lateral wall is equipped with and becomes piece tablet and collect storehouse 42.

The foregoing shows and describes the general principles, essential features, and advantages of the invention. It will be understood by those skilled in the art that the present invention is not limited to the above embodiments, and that the principles of the present invention may be applied to any other embodiment without departing from the spirit and scope of the present invention. The scope of the invention is defined by the appended claims and equivalents thereof.

Claims

1. A tablet processing mixing granulating tablet press comprises a mixing granulating barrel (1), a drying screen device (2), a tablet press (3) and a tablet sieving machine (4), wherein the mixing granulating barrel (1) is connected with the drying screen device (2) through a discharge pipeline (17), the drying screen device (2) is connected with a feeding end (31) of the tablet press (3) through a pipeline, the tablet press (3) is connected with the tablet sieving machine (4) through a pipeline, the top of the mixing granulating barrel (1) is provided with a feeding port (11), an observation port (12) and a liquid inlet system (16), and the tablet press is characterized in that the liquid inlet system (16) comprises a liquid inlet pipeline (160) which is horizontally arranged, and a plurality of spraying ports (1601) are arranged on the liquid inlet pipeline (160);

a first stirring shaft (13) is arranged at the bottom of the mixing and granulating barrel (1), an arc-shaped mixing knife (130) is arranged on the first stirring shaft (13), a high-speed cutting knife (14) and a granulating knife (15) are arranged on the side wall of the mixing and granulating barrel (1), and the high-speed cutting knife (14) and the granulating knife (15) are positioned on two sides of the central axis of the mixing and granulating barrel (1);

drying screen device (2) are arranged material pipe (23) including double-deck screen cloth (20), heating pipe (21), dust storehouse (22) and fine aggregate, double-deck screen cloth (20) are including macroporous screen cloth (201) on upper strata and aperture screen cloth (202) of lower floor, heating pipe (21) set up double-deck screen cloth (20)'s below and periphery, fine aggregate arrange material pipe (23) with aperture screen cloth (202) end connection.

2. A tablet press according to claim 1, wherein the inlet system (16) further comprises a humidity sensor (161), a control system (162), a water feeder (163) and a flow control valve (165), the control system (162) electrically connecting the humidity sensor (161) and the water feeder (163).

3. A tablet press according to claim 1, wherein the inlet duct (160) is a horizontally arranged horizontal or circular tube.

4. A tablet press according to claim 1, where the granulating knives (15) are located above the arc-shaped mixing knives (130) and the high speed cutting knives (14) are located above the horizontal plane of the granulating knives (15).

5. A tablet processing mixing granulation tablet press according to claim 4, characterized in that the granulation knives (15) consist of 4-6 sets of blades arranged parallel to the side wall of the mixing granulation cylinder (1).

6. A tablet processing mixing granulation tablet press according to claim 1, characterized in that the large mesh screen (201) has a pore size slightly larger than the particle size of the granules prepared from the compounding granulation drum (1), and the small mesh screen (202) has a pore size smaller than the particle size of the granules prepared from the compounding granulation drum (1).

7. A tablet processing mixing granulating tablet press as claimed in claim 1, wherein the bottom of the tablet sieving machine (4) is provided with a dust collecting bin (41), and the side wall of the tablet sieving machine (4) is provided with a tablet collecting bin (42).