CN210347273U

CN210347273U - Online automatic magnetic nano-material oscillation-desorption device

Info

Publication number: CN210347273U
Application number: CN201920982553.XU
Authority: CN
Inventors: 索德成; 于家丰; 樊霞; 王培龙; 李阳
Original assignee: Institute of Agricultural Quality Standards and Testing Technology for Agro Products of CAAS
Current assignee: Institute of Agricultural Quality Standards and Testing Technology for Agro Products of CAAS
Priority date: 2019-06-27
Filing date: 2019-06-27
Publication date: 2020-04-17
Anticipated expiration: 2029-06-27

Abstract

The utility model discloses an online automatic magnetic nano-material vibrates-desorption device, comprises an operation bench, the vibrating device has been arranged on the operation panel, add magnetic unit, demagnetization unit and slide bar, the slide bar connection has independent operation unit, independent operation unit can move on the slide bar, independent operation unit includes screw rod and electromagnetic lever, be connected with the arm on the electromagnetic lever, arm fixedly connected with sample cell tongs, sample cell tongs is connected with the sample cell rack, the sample cell is loaded on the sample cell rack, vibrating device, add magnetic unit, demagnetization unit and the equal electric connection control platform of independent operation unit. The utility model discloses can carry out low concentration bulky extraction to multiunit sample solution in succession, little volume desorption, the enrichment multiple is high, and sensitivity is high, and convenient operation, very big manpower and materials of having saved have improved work efficiency, have realized automation, intellectuality, the serialization of whole operation flow.

Description

Online automatic magnetic nano-material oscillation-desorption device

Technical Field

The utility model belongs to the analytical chemistry instrument field, in particular to automatic magnetic solid phase extraction device specifically is an online automatic magnetic nano-material vibrates-desorption device.

Background

Magnetic materials, which are generally referred to as ferromagnetic materials, are ancient functional materials with wide application, and the magnetism of the materials has been recognized and applied as early as 3000 years ago. Magnetic Nanomaterials (MNPs) refer to materials having a particle size generally in the order of nanometers and having a good magnetic response. The material not only has the common characteristics of nano materials, such as surface effect, quantum size effect and the like, but also has special magnetic properties (superparamagnetism, high coercivity and magnetic susceptibility) and good biocompatibility.

In recent years, in terms of sample pretreatment, magnetic nanomaterials are widely used, namely, a magnetic purification pretreatment method, which is a revolutionary technology in the separation and enrichment field in the 21 st century. ME is a dispersed solid phase extraction technique using magnetic or magnetizable materials as the adsorbent matrix. The principle is that the magnetic material or the modified magnetic material is used as a carrier, and under the action of a certain magnetic field, the target object is quickly separated from a complex environment system through operations such as adsorption, cleaning, elution and the like. Compared with the separation technology of non-magnetic materials, the technology has the obvious advantage that the magnetic materials can rapidly separate the analyte from the sample solution under a certain external magnetic field due to the magnetic property, and complex and time-consuming operations such as centrifugation, filtration and the like are not needed. Compared with the conventional extraction (SPE) filler, the magnetic material particles have large specific surface area and short diffusion distance, can realize low-concentration extraction only by using a small amount of adsorbent and short balance time, and has very high extraction capacity and extraction efficiency. ME widens the application range of the traditional extraction and shows obvious advantages in the aspect of sample pretreatment. ME has avoided processes such as consuming time dress post, loading, and the adsorbent disperses in sample solution and the area of contact of target object is showing to increase to shorten the extraction time, adsorbent after wasing, can used repeatedly many times. Therefore, the magnetic solid phase extraction is a simple, efficient and environment-friendly pretreatment technology.

The magnetic solid phase extraction technology is widely applied to the pretreatment process of actual samples, can extract various target objects such as various environmental hormones, heavy metal ions, toxic and harmful gases and other substances, and related sample matrixes are also rich in types such as environmental water samples, vegetables and fruits, grain crops, food packages and the like. In prior studies, magnetic solid phase extraction generally did not have an immobilized instrument set. The traditional magnetic material reactor is mainly applied to the field of water treatment, so the existing magnetic material reactor is usually separated by natural sedimentation or centrifugation by utilizing the excellent sedimentation performance of the magnetic material reactor, and the natural sedimentation separation is easy to cause material loss, such as pipeline residue, wall adsorption, water flow carrying and the like. Therefore, the traditional magnetic material reactor cannot meet the requirement of high-efficiency separation and recovery of magnetic solid-phase extraction.

Conventional analysis of large numbers of samples often requires rapid, repeatable and reliable data, which has prompted the development of automation techniques and other related technologies. The advantages of this technique are that the consumed solvent and reagent amount is small, the processing time is short, the cost is low, and the recovery rate and enrichment factor are high. Therefore, the ME technology and the automatic operation technology are combined to be a new technology developed in the field of sample pretreatment.

SUMMERY OF THE UTILITY MODEL

The utility model provides an on-line automatic magnetic nano-material oscillation-desorption device for solving the problems.

The utility model provides an online automatic magnetic nano-material vibrates-desorption device, includes the operation panel, vibrating device, add magnetic unit, demagnetization unit and slide bar have been arranged on the operation panel, the slide bar is connected with the independent operation unit, the independent operation unit can move on the slide bar, the independent operation unit includes screw rod and electromagnetic pole, be connected with the arm on the electromagnetic pole, arm fixedly connected with sample cell tongs, sample cell tongs is connected with the sample cell rack, the last sample cell that loads of sample cell rack, vibrating device, add the equal electric connection control platform of magnetic unit, demagnetization unit and independent operation unit.

The independent operation unit also comprises a liquid inlet device connected to the electromagnetic rod.

The magnetizing unit is a permanent magnet or an electromagnetic coil.

The degaussing unit fixes an electromagnetic coil, and the on-off of the electromagnetic coil is controlled by a time delay relay.

And water, extracting solution, desorbent or other solutions are respectively conveyed into the liquid inlet device.

The utility model discloses possess following beneficial effect:

1. the device has completely overcome loaded down with trivial details operation processes such as filling post, separation or centrifugation in the automatic extraction device, has combined the characteristics of ME technique, has simplified whole operation process, has increased substantially work efficiency.

2. The whole device realizes intellectualization, automation and continuity, and achieves the purposes of extraction, oscillation, desorption, collection, detection and the like by automatically processing the sample, the adsorbent, the water and the resolving agent under the control of a program.

3. The automatic device is convenient to operate, simple and quick, and experimental errors are greatly reduced.

4. The device can be used for processing and analyzing low-concentration large-volume samples, and the desorbent is flexible to add and high in enrichment times, so that the device is suitable for establishing a high-sensitivity analysis method.

5. The whole device has simple structure, can simultaneously process 10-40 samples after extraction, desorption and detection are finished every time, does not need to disassemble any part for replacement or other processing, only takes 5min for processing and analyzing one sample, has high working efficiency, and can analyze and determine samples in large batch.

Drawings

FIG. 1 is a schematic structural view of the present invention;

in the figure: 1. the device comprises an operation table, 2, a vibration device, 3, a magnetism adding unit, 4, a demagnetization unit, 5, a sliding rod, 6, a screw rod, 7, an electromagnetic rod, 8, a mechanical arm, 9, a sample tube gripper, 10, a sample tube placing frame, 11, a sample tube, 12, a control table, 13 and a liquid inlet device.

Detailed Description

In order to make the present invention better understood by those skilled in the art, the technical solutions of the present invention are further described below with reference to the accompanying drawings and examples.

The utility model provides an online automatic magnetic nano-material vibrates-desorption device, includes operation panel 1, vibration device 2, add magnetic unit 3, demagnetization unit 4 and slide bar 5 have been arranged on operation panel 1, slide bar 5 is connected with independent operation unit, independent operation unit can move on the slide bar 5, utilize the high accuracy micromotor to rotate the mode of screw rod and realize accurate perpendicular horizontal migration on the slide bar, independent operation unit includes screw rod 6 and electromagnetic bar 7, be connected with arm 8 on the

electromagnetic bar

7, 8 fixedly connected with sample cell tongs 9 of arm, sample cell tongs 9 is connected with sample cell rack 10, sample cell rack 10 is last to be loaded with sample cell 11, vibration device 2, add magnetic unit 3, demagnetization unit 4 and the equal electric connection control platform 12 of independent operation unit.

Further, the independent operating unit further comprises a liquid inlet device 13 connected to the electromagnetic rod 7.

Further, the magnetizing unit 3 is a permanent magnet or an electromagnetic coil.

Further, the demagnetization unit 4 fixes an electromagnetic coil, and the on-off of the electromagnetic coil is controlled by a time delay relay.

Further, the liquid inlet device 13 is used for respectively conveying water, extracting solution and desorbent.

The sample solution and the magnetic adsorbent are respectively added into the sample tube, and the sample tube is transferred into different functional areas by using a mechanical arm, so that liquid adding, elution, cleaning, magnetization, demagnetization and extraction oscillation are realized. When the device works, a sample and a magnetic adsorbent are respectively conveyed into a sample tube by a liquid inlet device or manually and are mixed, automatic oscillation is carried out in an oscillation device, and a target object is adsorbed on the surface of a magnetic material; when the sample tube passes through the magnetism adding unit, under the action of the magnetic field of the high-strength permanent magnet, the magnetic material is adsorbed at the bottom end, and the waste liquid is discharged; then, under the conveying of the liquid inlet device, the cleaning liquid is filled in the sample tube and then transferred to the oscillating device to enable the adsorbent to vibrate up and down quickly. Then transferring to a demagnetization unit, collecting the magnetized and magnetic materials to the bottom end of the sample tube under the action of a magnetic field, and transferring the cleaning liquid in the tube to a waste liquid bottle under the conveying of a waste liquid tube; under the conveying of the liquid inlet device, the eluent is filled in the sample tube, and then the sample tube is transferred to the oscillating device to enable the magnetic material to vibrate up and down rapidly and contact the eluent fully, so that target molecules are desorbed into the eluent; and after complete desorption, transferring to a demagnetization unit, collecting the magnetic material to the bottom end of the sample tube under the action of a magnetic field, finally, collecting the eluent under the conveying of the liquid inlet device, and then processing the next batch of products.

The device not only overcomes the complex operation processes of filling columns, separating or centrifuging and the like in the solid phase extraction device, but also enables two different platforms to control samples such as magnetic adsorbents and the like by moving so as to achieve the purposes of collection, desorption and the like, and is convenient to operate and easy to control; the device can process 10-40 samples at a time. The device controls the two electromagnetic coils to alternately generate a magnetic field through the time delay relay so as to control the magnetic adsorbent, thereby avoiding the loss of the magnetic adsorbent and having flexible and convenient operation; the device can be used to process samples continuously without replacing or handling any parts before processing the next sample.

The above-mentioned embodiments only represent the preferred embodiments of the present invention, and the description thereof is more specific and detailed, but not to be construed as limiting the scope of the present invention. It should be noted that, for those skilled in the art, without departing from the spirit of the present invention, several changes, modifications and substitutions can be made, which are all within the scope of the present invention. Therefore, the protection scope of the present invention should be subject to the appended claims.

Claims

1. An on-line automatic magnetic nano material oscillation-desorption device is characterized by comprising an operation table (1), the operating platform (1) is provided with a vibration device (2), a magnetizing unit (3), a demagnetizing unit (4) and a slide bar (5), the slide bar (5) is connected with an independent operation unit which can move on the slide bar (5), the independent operation unit comprises a screw rod (6) and an electromagnetic rod (7), the electromagnetic rod (7) is connected with a mechanical arm (8), the mechanical arm (8) is fixedly connected with a sample tube gripper (9), the sample tube gripper (9) is connected with a sample tube placing rack (10), the sample tube placing rack (10) is loaded with sample tubes (11), and the oscillating device (2), the magnetizing unit (3), the demagnetizing unit (4) and the independent operation unit are all electrically connected with the console (12).

2. An on-line automated magnetic nanomaterial shock-desorption device according to claim 1, characterized in that the independent operation unit further comprises a liquid inlet device (13) connected to the electromagnetic rod (7).

3. The on-line automatic magnetic nanomaterial oscillation-desorption device of claim 1 or 2, characterized in that the magnetizing unit (3) is a permanent magnet or an electromagnetic coil.

4. The on-line automatic magnetic nano material oscillation-desorption device according to claim 1 or 2, wherein the demagnetization unit (4) is fixed with an electromagnetic coil, and the on-off of the electromagnetic coil is controlled by a time delay relay.

5. The on-line automatic magnetic nano material oscillation-desorption device according to claim 3, wherein the demagnetization unit (4) is fixed with an electromagnetic coil, and the on-off of the electromagnetic coil is controlled by a time delay relay.

6. The on-line automatic magnetic nano-material oscillation-desorption device according to claim 2, wherein the liquid inlet device (13) is used for respectively conveying water, extracting solution and desorbent.