CN210269704U - Sample loading device and capillary electrophoresis apparatus - Google Patents
Sample loading device and capillary electrophoresis apparatus Download PDFInfo
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- CN210269704U CN210269704U CN201921172986.5U CN201921172986U CN210269704U CN 210269704 U CN210269704 U CN 210269704U CN 201921172986 U CN201921172986 U CN 201921172986U CN 210269704 U CN210269704 U CN 210269704U
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Abstract
The utility model discloses a go up appearance device, wherein, including sample platform and three-dimensional removal subassembly, the sample bench is provided with first storage tank and second storage tank, and the sample board is placed in first storage tank, and the reaction liquid groove is placed in the second storage tank, and the sample platform sets up on the three-dimensional removal subassembly, and the three-dimensional removal subassembly can realize the removal of sample platform on three-dimensional side. The utility model also discloses a capillary electrophoresis apparatus. The utility model discloses a go up appearance device and capillary electrophoresis apparatus through structural design and the overall arrangement to sample platform and three-dimensional removal subassembly to make full use of motor, belt, slide rail structure's cooperation realizes the automation of removal, has practiced thrift installation space, has increased the integrated nature of device, has realized the target of equipment automation, miniaturization.
Description
Technical Field
The utility model relates to a biochemical detection area especially relates to a go up appearance device and use this capillary electrophoresis apparatus who goes up appearance device.
Background
Capillary electrophoresis detection technology is a main analysis technology at present, and is widely applied to various fields by virtue of the characteristics of high efficiency, sensitivity, rapidness, simple equipment, strong applicability and the like. The method is a novel liquid phase separation technology which takes a capillary tube as a separation channel and takes a high-voltage direct-current electric field as a driving force. Capillary electrophoresis, which in fact comprises electrophoresis, chromatography and their cross-over, allows analytical chemistry to go from microliter levels to nanoliter levels and enables single cell analysis, and even single molecule analysis.
With the rapid development of gene diagnosis, identity recognition, molecular breeding, transgenic detection and the like, the sample loading device in the current capillary electrophoresis detection technology can not meet various requirements of the current biotechnology, particularly the requirements of miniaturization, integration and automation.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to provide an automatic, miniaturized appearance device and capillary electrophoresis apparatus of going up.
In order to achieve the above object, the utility model discloses a concrete technical scheme who goes up appearance device and capillary electrophoresis apparatus is:
a sample loading device comprises a sample platform and a three-dimensional moving assembly, wherein a first accommodating groove and a second accommodating groove are formed in the sample platform, a sample plate is placed in the first accommodating groove, a reaction liquid groove is placed in the second accommodating groove, the sample platform is arranged on the three-dimensional moving assembly, and the three-dimensional moving assembly can realize movement of the sample platform in the three-dimensional direction.
Further, the reaction liquid tank comprises a first chamber and a second chamber, the first chamber is used for containing cathode buffer liquid for providing a buffer system and a conductive medium for the electrophoresis process, and the second chamber is used for containing pure water for discharging waste glue and cleaning the capillary.
Furthermore, the three-dimensional moving assembly comprises a first direction moving unit, a second direction moving unit and a third direction moving unit, the sample stage is arranged on the third direction moving unit, the third direction moving unit is arranged on the second direction moving unit, the second direction moving unit is arranged on the first direction moving unit, the first direction moving unit is arranged on the installation bottom plate, and the sample stage can move in the three-dimensional direction through the first direction moving unit, the second direction moving unit and the third direction moving unit.
Further, the first direction movement unit comprises a first motor, a first belt and a first slide rail, the first slide rail is fixedly arranged on the mounting base plate, the first motor is connected with the first belt, a first bearing table is fixedly arranged on the first belt, a first sliding block is fixedly arranged on the first bearing table, and the first sliding block is arranged on the first slide rail in a sliding mode.
Furthermore, the second direction movement unit comprises a second motor, a second belt and a second slide rail, the second slide rail is fixedly arranged on the first bearing table, the second motor is connected with the second belt, the second bearing table is fixedly arranged on the second belt, a second slide block is fixedly arranged on the second bearing table, and the second slide block is arranged on the second slide rail in a sliding manner.
Further, the extending directions of the first slide rail and the second slide rail are mutually vertical.
Furthermore, the third direction movement unit comprises a third motor, the third motor is fixedly arranged on the sample platform, a motor shaft of the third motor is connected with the third bearing platform, the third bearing platform is fixedly arranged on the second bearing platform, a third sliding rail is arranged on the third bearing platform, a third sliding block is fixedly arranged on the sample platform, and the third sliding block is arranged on the third sliding rail in a sliding manner.
Further, the extending directions of the first slide rail, the second slide rail and the third slide rail are mutually vertical.
Furthermore, a first fixing piece is arranged on the installation bottom plate, a second fixing piece is arranged on the sample platform, and the first fixing piece and the second fixing piece are connected to enable the sample platform to be fixed.
A capillary electrophoresis apparatus comprising the loading device of any one of the above.
The utility model discloses a go up appearance device and capillary electrophoresis apparatus has following advantage: through structural design and the overall arrangement to sample platform and three-dimensional removal subassembly to the cooperation of make full use of motor, belt, slide rail structure realizes the automation of removal, has practiced thrift installation space, has increased the integrated nature of device, has realized the automatic, miniaturized target of equipment.
Drawings
Fig. 1 is a first perspective view of a sample loading device of the present invention;
fig. 2 is a second perspective view of the sample loading device of the present invention;
fig. 3 is a perspective view of a sample stage in the sample loading device of the present invention;
FIG. 4 is a perspective view of a reaction liquid tank in the sample stage according to the present invention;
fig. 5 is a perspective view of a three-dimensional moving assembly in a sample loading device according to the present invention;
fig. 6 is a perspective view of the first direction moving unit and the second direction moving unit in the three-dimensional moving assembly of the present invention;
fig. 7 is a partial enlarged view of the first direction moving unit and the second direction moving unit in the three-dimensional moving assembly of the present invention;
fig. 8 is a perspective view of the first direction moving unit, the second direction moving unit and the third direction moving unit in the three-dimensional moving assembly of the present invention;
fig. 9 is a partial enlarged view of the first direction moving unit, the second direction moving unit and the third direction moving unit in the three-dimensional moving assembly of the present invention.
Detailed Description
For better understanding of the purpose, structure and function of the present invention, the following description will be made in detail with reference to the accompanying drawings.
As shown in fig. 1 and fig. 2, the sample loading device of the present invention includes a sample stage 1 and a three-dimensional moving assembly 2, wherein the sample stage 1 is disposed on the three-dimensional moving assembly 2, and the three-dimensional moving assembly 2 can realize the movement of the sample stage 1 in the three-dimensional direction. It should be noted that the utility model provides a sample loading device can be used to automatic check out test set such as capillary electrophoresis apparatus to realize check out test set's automatic sample loading.
Specifically, as shown in fig. 3 and 4, in the present embodiment, the sample stage 1 is provided with a first accommodating groove and a second accommodating groove, wherein the sample plate 3 is placed in the first accommodating groove, and the sample plate 3 may be a 96-well plate or the like for accommodating a sample to be detected; the reaction liquid tank 4 is placed in the second containing tank, the reaction liquid tank 4 comprises a first chamber 41 and a second chamber 42, the first chamber 41 contains a cathode buffer solution, the second chamber 42 contains pure water, the cathode buffer solution can provide a buffer system and a conductive medium for the electrophoresis process, and the pure water can be used for discharging waste glue and cleaning capillaries.
Therefore, in the electrophoresis process, waste glue can be firstly discharged in pure water of the reaction liquid tank 4, then sample introduction is carried out in the sample plate 3 by means of potential difference, and finally electrophoresis is carried out in cathode buffer solution, wherein the sample plate is required to be washed in the pure water when different tanks are switched, and the three-dimensional movement of the sample platform 1 is controlled by the three-dimensional moving assembly 2 so as to complete the switching among the different tanks. In addition, optionally, during the electrophoresis, the waste gel may be first removed from the pure water in the reaction liquid tank 4, then pre-electrophoresis is performed in the cathode buffer solution in the reaction liquid tank 4, then sample injection is performed in the sample plate 3 by means of potential difference, and finally electrophoresis is performed in the cathode buffer solution. Of course, it is understood that different operation procedures can be selected according to different situations, and the above is only a preferred example and is not limited in detail.
As shown in fig. 5 to 9, in the present embodiment, the three-dimensional moving assembly 2 includes a first-direction moving unit, a second-direction moving unit, and a third-direction moving unit, wherein the specimen stage 1 is disposed on the third-direction moving unit, the third-direction moving unit is disposed on the second-direction moving unit, the second-direction moving unit is disposed on the first-direction moving unit, and the first-direction moving unit is disposed on the mounting base plate 5.
Preferably, the first direction moving unit in this embodiment may realize the movement of the sample stage 1 in the X-axis direction, the second direction moving unit may realize the movement of the sample stage 1 in the Y-axis direction, and the third direction moving unit may realize the movement of the sample stage 1 in the Z-axis direction. Thus, the movement of the specimen stage 1 in the three-dimensional direction can be realized by the first direction moving unit, the second direction moving unit, and the third direction moving unit.
Further, as shown in fig. 6 to 9, in this embodiment, the first direction moving unit includes a first motor 211, a first belt 212 and a first slide rail 213, wherein the first slide rail 213 is fixedly disposed on the mounting base plate 5, the first motor 211 is connected to the first belt 212, a first loading platform 214 is fixedly disposed on the first belt 212, a first sliding block 215 is fixedly disposed on the first loading platform 214, and the first sliding block 215 is slidably disposed on the first slide rail 213. Therefore, the first motor 211 can drive the first belt 212 to rotate, and when the first belt 212 rotates, the first loading platform 214 can be synchronously driven to move, so as to drive the first sliding block 215 to move along the first sliding rail 213, so as to realize the movement of the sample platform 1 in the X-axis direction.
Further, the second direction moving unit includes a second motor 221, a second belt 222 and a second slide rail 223, wherein the second slide rail 223 is fixedly disposed on the first bearing platform 214, the second motor 221 is connected to the second belt 222, the second belt 222 is fixedly disposed with a second bearing platform 224, the second bearing platform 224 is fixedly disposed with a second sliding block 225, and the second sliding block 225 is slidably disposed on the second slide rail 223. Therefore, the second motor 221 can drive the second belt 222 to rotate, and when the second belt 222 rotates, the second bearing platform 224 can be synchronously driven to move, so as to drive the second sliding block 225 to move along the second sliding rail 223, so as to realize the movement of the sample platform 1 in the Y-axis direction.
Further, the third direction moving unit includes a third motor 231, wherein the third motor 231 is fixedly disposed on the sample stage 1, a motor shaft of the third motor 231 is connected to a third bearing stage 232, the third bearing stage 232 is fixedly disposed on the second bearing stage 224, a third slide rail 233 is disposed on the third bearing stage 232, a third slide block 234 is fixedly disposed on the sample stage 1, and the third slide block 234 is slidably disposed on the third slide rail 233. Therefore, the extension of the motor shaft of the third motor 231 can move the sample stage 1 toward a direction away from the third bearing stage 232, so that the third slide 234 on the sample stage 1 moves along the third slide rail 233 on the third bearing stage 232, thereby realizing the movement of the sample stage 1 in the Z-axis direction.
In general, the sample stage 1 is fixedly connected to the third slide block 234, the third slide block 234 is slidably connected to the third slide rail 233, the third slide rail 233 is fixedly connected to the third bearing stage 232, and the third bearing stage 232 is fixedly connected to the second bearing stage 224; the second bearing table 224 is fixedly connected with a second sliding block 225, the second sliding block 225 is slidably connected with a second sliding rail 223, and the second sliding rail 223 is fixedly connected with the first bearing table 214; the first bearing platform 214 is fixedly connected with the first sliding block 215, the first sliding block 215 is slidably connected with the first sliding rail 213, and the first sliding rail 213 is fixedly arranged on the installation bottom plate 5.
Wherein the extending directions of the first slide rail 213, the second slide rail 223 and the third slide rail 233 are perpendicular to each other. Therefore, the motor shaft of the third motor 231 extends or retracts to drive the sample stage 1 to reciprocate in the extending direction of the third slide rail 233; the second motor 221 drives the second belt 222 to rotate, so as to drive the sample stage 1 to reciprocate in the extending direction of the second slide rail 223; the first motor 211 drives the first belt 212 to rotate, so as to drive the sample stage 1 to reciprocate in the extending direction of the first slide rail 213.
Further, as shown in fig. 5, in the embodiment, the mounting base plate 5 is provided with a first fixing member 61, the sample stage 1 is provided with a second fixing member 62, and the first fixing member 61 and the second fixing member 62 can be connected with each other, so that the sample stage 1 is temporarily fixed relative to the mounting base plate 5, thereby solving the problem that the sample stage 1 may slide freely during transportation and ensuring the safety of the device.
The utility model discloses a go up appearance device and capillary electrophoresis apparatus through structural design and the overall arrangement to sample platform and three-dimensional removal subassembly to make full use of motor, belt, slide rail structure's cooperation realizes the automation of removal, has practiced thrift installation space, has increased the integrated nature of device, has realized the target of equipment automation, miniaturization.
The present invention has been further described with reference to specific embodiments, but it should be understood that the specific description herein should not be construed as limiting the spirit and scope of the present invention, and that various modifications to the above-described embodiments, which would occur to persons skilled in the art after reading this specification, are within the scope of the present invention.
Claims (10)
1. The sample loading device is characterized by comprising a sample platform and a three-dimensional moving assembly, wherein a first accommodating groove and a second accommodating groove are formed in the sample platform, a sample plate is placed in the first accommodating groove, a reaction liquid groove is placed in the second accommodating groove, the sample platform is arranged on the three-dimensional moving assembly, and the three-dimensional moving assembly can realize the movement of the sample platform in the three-dimensional direction.
2. The loading device according to claim 1, wherein the reaction liquid tank comprises a first chamber and a second chamber, the first chamber is used for containing a cathode buffer solution for providing a buffer system and a conductive medium for the electrophoresis process, and the second chamber is used for containing pure water for discharging waste gel and cleaning the capillary.
3. The loading device of claim 1, wherein the three-dimensional moving assembly comprises a first direction moving unit, a second direction moving unit and a third direction moving unit, the sample stage is arranged on the third direction moving unit, the third direction moving unit is arranged on the second direction moving unit, the second direction moving unit is arranged on the first direction moving unit, the first direction moving unit is arranged on the mounting base plate, and the movement of the sample stage in the three-dimensional direction can be realized through the first direction moving unit, the second direction moving unit and the third direction moving unit.
4. The sample loading device according to claim 3, wherein the first direction moving unit comprises a first motor, a first belt and a first slide rail, the first slide rail is fixedly arranged on the mounting base plate, the first motor is connected with the first belt, a first bearing table is fixedly arranged on the first belt, a first slide block is fixedly arranged on the first bearing table, and the first slide block is slidably arranged on the first slide rail.
5. The sample loading device according to claim 4, wherein the second direction moving unit comprises a second motor, a second belt and a second slide rail, the second slide rail is fixedly arranged on the first bearing platform, the second motor is connected with the second belt, the second bearing platform is fixedly arranged on the second belt, a second slide block is fixedly arranged on the second bearing platform, and the second slide block is slidably arranged on the second slide rail.
6. The loading device of claim 5, wherein the first and second slide rails extend in a direction perpendicular to each other.
7. The sample loading device according to claim 5, wherein the third direction moving unit comprises a third motor, the third motor is fixedly arranged on the sample stage, a motor shaft of the third motor is connected with a third bearing stage, the third bearing stage is fixedly arranged on the second bearing stage, a third slide rail is arranged on the third bearing stage, a third slide block is fixedly arranged on the sample stage, and the third slide block is slidably arranged on the third slide rail.
8. The loading device of claim 7, wherein the first, second and third slide rails extend in directions perpendicular to each other.
9. A sample loading device as claimed in any one of claims 3 to 8, wherein the mounting base plate is provided with a first fixing member, the sample stage is provided with a second fixing member, and the first fixing member and the second fixing member are connected to fix the sample stage.
10. A capillary electrophoresis apparatus comprising the loading device according to any one of claims 1 to 9.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201921172986.5U CN210269704U (en) | 2019-07-24 | 2019-07-24 | Sample loading device and capillary electrophoresis apparatus |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201921172986.5U CN210269704U (en) | 2019-07-24 | 2019-07-24 | Sample loading device and capillary electrophoresis apparatus |
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| Publication Number | Publication Date |
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| CN210269704U true CN210269704U (en) | 2020-04-07 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201921172986.5U Active CN210269704U (en) | 2019-07-24 | 2019-07-24 | Sample loading device and capillary electrophoresis apparatus |
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| CN (1) | CN210269704U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116218649A (en) * | 2022-12-30 | 2023-06-06 | 德诺杰亿（北京）生物科技有限公司 | Automatic calibration method and device for sample loading table of gene analyzer and gene analyzer |
| CN116218649B (en) * | 2022-12-30 | 2024-07-02 | 德诺杰亿（北京）生物科技有限公司 | Automatic calibration method and device for sample loading table of gene analyzer and gene analyzer |
-
2019
- 2019-07-24 CN CN201921172986.5U patent/CN210269704U/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116218649A (en) * | 2022-12-30 | 2023-06-06 | 德诺杰亿（北京）生物科技有限公司 | Automatic calibration method and device for sample loading table of gene analyzer and gene analyzer |
| CN116218649B (en) * | 2022-12-30 | 2024-07-02 | 德诺杰亿（北京）生物科技有限公司 | Automatic calibration method and device for sample loading table of gene analyzer and gene analyzer |
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