CN210252344U

CN210252344U - Liquid sample collection device

Info

Publication number: CN210252344U
Application number: CN201920521106.4U
Authority: CN
Inventors: 托德·贝利; 罗琳·C·科根; 洪亮; 朱杨煜; 吴强
Original assignee: Hangzhou Biotest Biotech Co Ltd
Current assignee: Hangzhou Biotest Biotech Co Ltd
Priority date: 2019-04-17
Filing date: 2019-04-17
Publication date: 2020-04-07
Anticipated expiration: 2029-04-17

Abstract

The utility model provides a liquid sample collection device, compact structure can not only make the device firm place, prevent that the device from empting, can also make things convenient for the installation in storage chamber and carry out real-time supervision to the condition of the interior liquid sample of storage chamber. The device is including collection chamber and the storage chamber that is used for collecting liquid sample, and collection chamber and storage chamber detachable combination, the device has the appearance chamber that is used for holding the storage chamber, holds the chamber and has the opening, and when storage chamber and collection chamber combination, the storage chamber can be followed and held the chamber opening and expose.

Description

Liquid sample collection device

Technical Field

The utility model relates to a short-term test field specifically relates to a liquid sample collection device.

Background

The following background is provided to aid the reader in understanding the present invention and is not admitted to be prior art.

Rapid test devices for medical or home use are commonly used to detect whether a sample contains an analyte, such as for early pregnancy tests, drug tests, and the like. The test device contains a test element, such as a test strip, which is typically used for the initial testing of the sample. Therefore, the detection device is provided with a collection cavity for collecting a sample and a detection cavity for accommodating a test element, wherein the collection cavity is in fluid communication with the detection cavity, so that the collection and the primary detection of the sample can be simultaneously realized through one-time sampling.

In the existing testing devices, the collection chamber and the testing chamber have respective openings, the opening of the collection chamber is used for the inflow of the liquid sample, and the opening of the testing chamber is used for the insertion of the testing element. After the liquid sample is collected, in order to prevent leakage and to prevent the liquid sample from being polluted by the outside, the opening of the collection cavity and the opening of the detection cavity need to be respectively sealed, but because the distance between the collection cavity and the detection cavity is small, one of the collection cavity and the detection cavity is easily interfered by the other, and the operation is very inconvenient. In addition, in order to fix the test element in the detection chamber and prevent the test element from shaking during the initial detection process and affecting the detection result, a fixing member needs to be provided on the test element or in the detection chamber. The dimensions of the test element and the detection chamber themselves are small, and the dimensions of the parts for fixing are also relatively small, which easily results in the fixing of the test element being inconvenient or even not firm.

In order to make the detection result more accurate or for other reasons, the sample to be detected may need to be subjected to secondary detection. In the case where the secondary detection of the sample is required, in order to avoid contamination of the sample for the secondary detection by the test element, it is necessary to isolate the collected secondary detection sample from the sample for the primary detection. The detection device is therefore also provided with a storage chamber, which is usually detachably connected to the collection chamber. When the storage chamber is connected to the collection chamber, the storage chamber is in fluid communication with the collection chamber such that the sample can pass through the collection chamber into the storage chamber; when the sample in the storage cavity is completely collected, the storage cavity can be detached from the collection cavity and sealed, so that the sample in the storage cavity can be independently sent to the detection mechanism for secondary detection. To facilitate the flow of the sample into the storage chamber, the storage chamber is typically provided at the bottom of the test device; in order to facilitate the installation and the placement of the detection device, the detection device is also provided with a base. The base and the storage cavity are respectively detachably connected with the collecting cavity, and the base is detachably connected with the storage cavity; when the base is connected with the collection chamber, the storage chamber is contained within the enclosed space formed by the collection chamber and the base. This leads to the following problems: firstly, when the base is connected with the collecting cavity, the storage cavity must be simultaneously connected with the collecting cavity, so that the base and the collecting cavity and the storage cavity and the collecting cavity need to be simultaneously and accurately aligned, and the operation difficulty is higher; the other is that the interference of the base can not conveniently monitor the condition of the sample in the storage cavity in real time, such as whether leakage occurs at the joint of the storage cavity and the collection cavity, how much sample is contained in the storage cavity, and the like.

On the other hand, in the detecting device provided with the storage chamber, a part of the sample in the collection chamber flows into the detection chamber for primary detection, and the other part flows into the storage chamber for secondary detection after being transferred from the storage chamber to another place, so that the collection chamber is not required to have a large capacity in practice, and even in some detecting devices, the large capacity of the collection chamber may cause unnecessary waste, for example, the whole volume of the detecting device is increased, the transportation cost is increased, and the like. The test element may need to be of a relatively large size for the test, for example, the test strip may have a reference zone, a control zone of the test zone, etc., and the zones may need to be spaced apart from each other, so that the test strip may need to have a certain length. Therefore, the detection device needs to be designed, the requirement of detection of the test element is met, and meanwhile, the whole structure of the detection device is more compact and the use is more convenient.

SUMMERY OF THE UTILITY MODEL

The utility model discloses a first aspect provides a collect and detect device of liquid sample, can realize collecting the chamber and detect sealed when the chamber, but also can conveniently fix the test element who detects the intracavity, increases the use convenience of device.

A device for collecting and testing a liquid sample, comprising a collection chamber for collecting the liquid sample, the collection chamber comprising a first section and a second section, a test chamber for receiving a test element being provided in the second section, the test chamber being in fluid communication with the second section, the first and second sections being capable of confining the test element between the first and second sections when the first and second sections are combined.

In some preferred modes, the first section is provided with a limiting part for limiting the position of the test element, the limiting part comprises a fixing part for fixing the test element, and when the first section and the second section are combined, the fixing part and the bottom of the detection cavity respectively abut against two ends of the test element. The test element is fixed between the fixing portion and the bottom of the detection chamber.

In some preferred modes, the fixing part is provided with a propping end for propping against the test element, and when the first section and the second section are combined, the propping end is positioned in the second section.

In some preferred modes, the limiting piece is provided with a connecting part used for being connected with the first section, and the connecting part is an elastic piece. With the help of the elastic sheet, when the position of the test element is limited by the limiting part, the force applied to the test element is elastic force, so that the limiting effect of the limiting part can be enhanced, and the damage of the limiting part to the test element is reduced. Preferably, one end of the fixing part is connected with the connecting part, and the other end of the fixing part is a propping end.

In some preferred forms, the stop comprises a stop portion for preventing the test element from tipping into the collection chamber, the stop portion being located between the test element and a middle portion of the second section when the test element is placed in the detection chamber and the first and second sections are combined. Preferably, when the test element is placed in the test chamber and the first and second sections are combined, the blocking portion is located between the test chamber and the middle of the second section.

In some preferred modes, one end of the blocking part is connected with the connecting part, the other end of the blocking part is a free end, and when the first section and the second section are combined, the free end of the blocking part is positioned in the second section. Preferably, the free end of the blocking part is close to the bottom of the second section relative to the abutting end of the fixing part. That is, the free end of the blocking portion is located below the abutting end of the fixing portion.

In some preferred forms, the first section and the second section are detachably combined or fixedly combined.

In some preferred modes, the first section is provided with a through hole used for being sleeved outside the second section, and when the through hole of the first section is sleeved outside the second section, the through hole of the first section is in clearance fit or interference fit with the second section. Preferably, the limiting member is arranged on the inner wall of the first section of the through hole. The limiting part is connected with the inner wall of the first section of through hole through the connecting part.

In some preferred modes, the through holes of the first section comprise a first through hole and a second through hole, the size of the first through hole is smaller than that of the second through hole, a step is arranged between the first through hole and the second through hole, when the first section and the second section are combined, the second through hole is sleeved outside the second section, the first through hole is positioned on the second section, and the step between the first through hole and the second through hole is abutted against the second section. When the first and second sections are combined, the relative position between the first and second sections may be defined by a step between the first and second through holes. Preferably, the second section is provided with a protrusion, when the first section and the second section are combined, the second through hole is sleeved outside the protrusion, and the step between the first through hole and the second through hole abuts against the protrusion. Preferably, the second section has an opening, and the protrusion is disposed at the opening of the second section. Preferably, the first through hole comprises a threaded section and a connecting section for connecting the threaded section and the second through hole, and the threaded section is provided with an external thread on the outer wall or an internal thread on the inner wall. Preferably, the limiting member is disposed on an inner wall of the first through hole.

A second aspect of the utility model provides a liquid sample collection device, compact structure can not only make the device stabilize and place, prevent that the device from empting, can also make things convenient for the installation in storage chamber and carry out real-time supervision to the condition of storing intracavity liquid sample.

In some preferred forms, the device includes a collection chamber for collecting the liquid sample and a storage chamber, the collection chamber and the storage chamber being removably assembled, the device having a receptacle for receiving the storage chamber, the receptacle having an opening through which the storage chamber can be exposed when the storage chamber is assembled with the collection chamber.

In some preferred forms, the chamber opening includes a first opening for insertion or removal of the storage chamber and/or a second opening for direct viewing of the storage chamber.

In some preferred modes, one end of the cavity is connected with the collecting cavity, and the first opening is positioned at the other end of the cavity; or the first opening is a through hole arranged on the side wall of the accommodating cavity. The side wall of the cavity is the wall for enclosing the cavity.

In some preferred modes, the second opening is a through hole formed in the side wall of the cavity. Preferably, the at least one second opening is located on one, two or more sides of the storage chamber when the storage chamber is combined with the collection chamber.

In some preferred forms, the device has a support member for supporting the collection chamber, the support member being connected to the collection chamber, the support member and the collection chamber together forming the receptacle. Preferably, one end of the supporting member is a connecting end connected with the collecting cavity, the other end of the supporting member is a free end, and the free end of the supporting member encloses the first opening. Preferably, the receptacle tapers in size from the free end of the support member to the connecting end of the support member to the collection chamber. Preferably, the end face of the free end of the support member lies in a horizontal plane.

In some preferred forms, the support member includes a support plate connected to the collection chamber, and the chamber side wall includes the support plate and a collection chamber outer wall. Preferably, the support plate is connected to the second section of the collection chamber. Preferably, the junction of the support plate and the second section is proximate the opening of the second section. Preferably, one end of the supporting plate is a connecting end connected with the collecting cavity, the other end of the supporting plate is a free end, and the free end of the supporting plate is enclosed to form a first opening. Preferably, the distance between the support plate and the midline of the collection chamber tapers from the free end of the support plate to the connected end of the support plate and the collection chamber.

In some preferred forms, the second opening is located in the support plate.

The third aspect of the utility model provides a device for detecting liquid sample, can conveniently survey in real time the testing process and testing result, need not to take up or empty the device, convenient operation, reduction weeping.

In some preferred forms, the kit comprises a collection chamber for collecting a liquid sample and a detection chamber for placing a test element, the collection chamber and the detection chamber being in fluid communication; the detection cavity is provided with a side wall for displaying the detection result of the test element, the side wall and the horizontal plane form an acute angle, and the detection cavity is positioned in the acute angle. When the device level was placed on the platform, need not to take up or slope detection device and can see through the lateral wall that detects the chamber and observe the testing element's testing result, increased the convenience of observing, reduced the weeping. Preferably, the side wall lies in a plane intersecting the horizontal plane.

In some preferred modes, the detection cavity is arranged in the collection cavity, and the collection cavity and the detection cavity have a common side wall which is a side wall for displaying the detection result of the test element. That is, the side walls for displaying the test results of the test elements are used to define both the collection chamber and the detection chamber.

In some preferred forms, the detection chamber is a chamber formed to project outwardly from the collection chamber, and the side walls of the receptacle include an outer detection chamber wall and an outer collection chamber wall. By receptacle is meant a receptacle for receiving a storage chamber. I.e. the detection chamber projects outwardly from the collection chamber to form a receptacle for receiving the storage chamber. Preferably, the detection chamber is a chamber formed to protrude outward from the bottom of the collection chamber. The opening of the detection chamber is located at the bottom of the collection chamber. That is, the detection chamber projects outwardly from the bottom of the collection chamber, not only for accommodating the test element, but also for supporting the entire device, and at the same time forms together with the outer wall of the collection chamber a receptacle for accommodating the storage chamber. Preferably, the bottom of the detection chamber encloses a first opening. The first opening refers to a first opening of the cavity. Preferably, the bottom of the detection chamber is located in a horizontal plane.

In some preferred modes, the device further comprises a supporting plate, the supporting plate is connected with the collecting cavity, and the side wall of the containing cavity comprises the supporting plate, the outer wall of the collecting cavity and the outer wall of the detection cavity. Preferably, one end of the supporting plate is a connecting end connected with the collecting cavity, the other end of the supporting plate is a free end, and the free end of the supporting plate is enclosed to form a first opening. Preferably, the bottom of the detection chamber and the free end of the support plate are located in the same horizontal plane.

In some preferred forms, the second opening is a through hole provided in the support plate.

The fourth aspect of the utility model provides a carrier of test element, at the in-process that the liquid sample flows in from collecting the chamber and detects the chamber, with the test element contact that detects the intracavity, this carrier can cushion the liquid sample velocity of flow, prevents that the velocity of flow of liquid sample is too big, influences test element's detection.

In some preferred forms, the test element carrier has an insertion portion for insertion into the detection chamber, and the insertion portion is provided with a buffer structure for cooperating with an inner wall of the detection chamber to slow down a flow rate of the liquid sample.

In some preferred forms, the buffer structure includes a baffle, and a gap for passing the liquid sample is formed between the baffle and an inner wall of the detection chamber when the insertion portion is located in the detection chamber. Preferably, when the insertion portion is inserted into the detection chamber, the plane of the baffle is perpendicular to the inner wall of the detection chamber.

In some preferred forms, the left side of the baffle is flush with the left side of the insert and the right side of the baffle is flush with the right side of the insert. Preferably, the axis of symmetry of the baffle and the median line of the test element lie on the same line.

In some preferred forms, the baffle is provided on the back side of the test element carrier. The side of the carrier for mounting the test element is the front side of the test element carrier, and the side opposite to the front side is the back side of the test element carrier.

In some preferred modes, the baffle plates are two or more, and when the insertion part is positioned in the detection cavity, the two or more baffle plates have height difference; the size of the gap between the baffle and the inner wall of the detection cavity is gradually reduced along with the increase of the height of the baffle.

In some preferred forms, the buffer structure further includes a support portion disposed at a bottom end of the insertion portion, and a channel for slowing down a flow rate of the liquid sample is formed between the support portion and a bottom of the detection chamber when the insertion portion is inserted into the detection chamber. The support part is used for supporting the whole test element carrier. The bottom end of the insertion portion refers to an end of the insertion portion near the bottom of the detection chamber when the insertion portion is located in the detection chamber. The liquid sample flows slowly through the channel from the back side of the test element carrier to the front side of the test element carrier and contacts the test element mounted to the front side of the test element carrier.

In some preferred modes, the supporting part comprises a blocking sheet, one end of the blocking sheet is connected with the inserting part, the other end of the blocking sheet is a free end, and the channel is formed between the end face of the free end of the blocking sheet and the bottom of the detection cavity. The distance between the bottom end of the insertion part and the bottom of the detection cavity is reduced by the blocking sheet, and the flow speed of the liquid sample is reduced under the blocking action of the blocking sheet when the liquid sample passes through the detection cavity.

In some preferred modes, when the insertion part is inserted into the detection cavity, the end face of the free end of the barrier sheet forms an included angle with the bottom of the detection cavity, and the opening of the included angle is opposite to the flowing direction of the liquid sample. That is, the end face of the free end of the blocking piece is an inclined plane, so that the size of a channel formed between the blocking piece and the bottom of the detection cavity is gradually reduced towards the flowing direction of the liquid sample, and the flow speed of the liquid sample is reduced when the liquid sample passes through the channel.

In some preferred forms, the support portion includes a projection for supporting the test element carrier, the projection having a contact surface for contacting the bottom of the detection chamber, the end surface of the free end of the blocking piece being located above the contact surface when the insertion portion is inserted into the detection chamber.

In some preferred modes, the lug has a free end, and the end face of the free end comprises a contact face and a bevel face intersected with the contact face, and the bevel face and the free end face of the blocking piece are located in the same plane.

The utility model has the advantages that:

1. the collecting cavity comprises a first section and a second section, the detection cavity is arranged in the second section, the collecting cavity and the detection cavity share one opening, and the detection cavity is sealed simultaneously when the collecting cavity is sealed, so that the use is convenient; when the first section and the second section are combined, the limit part of the first section is matched with the second section, so that the test element can be limited between the first section and the second section, and the test element is convenient to assemble and firm to fix.

2. The limiting part comprises a connecting part which is an elastic sheet, so that elastic force is applied when the limiting part limits the testing element, and the damage to the testing element is reduced; the locating part includes the stop part, and the stop part not only can prevent that test element from empting to collecting the intracavity, can also prevent that a large amount of liquid samples from directly pouring into and detecting the chamber, and the influence detects intracavity test element's detection.

3. The lateral wall that the detection chamber is used for showing test element testing result is the acute angle with the horizontal plane, and the detection chamber is located the acute angle, when observing test element's detection progress and testing result, need not to take up or empty detection device and can make test element's testing result expose in the sight, observes conveniently, reduces the weeping.

4. The device is provided with a supporting piece, the supporting piece is connected with the collecting cavity, the supporting piece and the collecting cavity jointly form a containing cavity for containing the storage cavity, and the storage cavity can be conveniently detached and connected with the collecting cavity through a first opening of the containing cavity; the support piece is set to be in an inverted triangle shape with a small upper part and a big lower part, so that the overall stability of the device is improved, and the device is not easy to topple when placed on the platform.

5. The cavity is provided with a second opening, and the storage condition of the liquid sample in the storage cavity can be conveniently monitored through the second opening, such as the condition that the liquid sample occupies the capacity of the storage cavity, whether the storage cavity leaks liquid and the like.

6. The detection cavity protrudes outwards from the collection cavity to form a part of the support piece, so that on one hand, the detection cavity can accommodate a test element with a certain size and can also support the collection cavity, and the bottom of the detection cavity forms a larger support surface, so that the support stability of the support piece to the device can be improved; on the other hand, the design more reasonably distributes the space occupied by the device and makes the device structure more compact.

7. The test element carrier is provided with a buffer structure which is used for being matched with the inner wall of the detection cavity and slowing down the flow velocity of the liquid sample, so that the excessive flow velocity of the liquid is prevented, the detection sensitivity of the test element is reduced, and even the test element fails, and the liquid sample can uniformly flow to each test element, so that the observation of a detection result is facilitated.

8. Buffer structure has the difference in height including setting up the baffle at the test element carrier back between two or the polylith baffle to the baffle with detect the size in clearance between the intracavity wall and reduce gradually along with the increase of baffle height, thereby two and polylith baffles form multi-level buffering to liquid sample, promote buffering effect.

9. The buffer structure also comprises a blocking sheet arranged at the bottom of the test element, a channel for slowing down the flow velocity of the liquid sample is formed between the free end of the blocking sheet and the bottom of the detection cavity, and the channel enables the liquid sample to be buffered again before flowing to the test element.

Drawings

Fig. 1 is an appearance schematic diagram of a detection device according to an embodiment of the present invention.

Fig. 2 is an overall sectional view of the detecting unit of fig. 1.

Fig. 3 is a schematic illustration of a first section and a second section of a collection chamber according to an embodiment of the invention.

Fig. 4 is a schematic view of the combination of the first section and the second section of the collection chamber according to an embodiment of the invention.

Fig. 5 is a perspective view of a first section of a collection chamber in an embodiment of the invention.

Figure 6 is a perspective view of the first section of the collection chamber of figure 5 at another angle.

Fig. 7 is a perspective view of a second section of a collection chamber in an embodiment of the invention.

Figure 8 is a perspective view of another angle of the second section of the collection chamber of figure 7.

Fig. 9 is a perspective view of a test element carrier in an embodiment of the invention.

Fig. 10 is a perspective view of the test element carrier of fig. 9 from another angle.

FIG. 11 is a bottom view of a test element carrier according to an embodiment of the present invention.

FIG. 12 is a schematic view of a bump on a test element carrier according to an embodiment of the present invention.

Fig. 13 is a schematic view of an opening of a chamber according to an embodiment of the present invention.

Detailed Description

Further description of the present invention will be made with respect to structural or technical terms, which are understood and interpreted according to common general terms in the art, unless otherwise specified.

Liquid sample

A liquid sample refers to a sample that is in the form of a flowable, liquid. The liquid sample may be derived from a solid or semi-solid sample. The solid or semi-solid sample may be converted to a liquid sample by any suitable method, for example mixing, triturating, macerating, incubating, dissolving or in a suitable solution. Liquid samples include biological samples, plant samples, food samples, environmental samples, and the like. Biological samples, for example, include urine, saliva, blood, spinal fluid, vaginal secretions, sperm, feces, sweat, secretions, tissues, organs, tumors, cultures of tissues and organs, cell cultures, and media derived from humans or animals. Plant samples include plant tissues, plant cell cultures, and media derived from any plant. Food samples include food processing materials, end products, meat, cheese, wine, milk, and drinking water. Environmental samples are derived from the environment, such as liquid samples from lakes or other bodies of water, sewage, soil samples, groundwater, seawater, and waste liquid samples.

Collection cavity

The collection chamber is a chamber for collecting the liquid sample, and is usually configured to be sealable in order to prevent the liquid sample from being contaminated by the outside world, and in some cases requiring transportation, to prevent the liquid sample from leaking from the collection chamber. In some devices, a test chamber is also provided, and the liquid sample can be initially tested using a test element placed within the test chamber. The collection cavity is in fluid communication with the detection cavity, so that the liquid sample can flow into the detection cavity after entering the collection cavity and contact with the test element in the detection cavity, and the test element detects the analyte in the liquid sample. To prevent contamination of the liquid sample during the initial test, the test chamber is also provided to be sealable. In the existing detection device, a collection cavity and a detection cavity are two relatively independent cavities, and the two cavities need to be respectively sealed when being sealed. However, the collection chamber and the detection chamber are separated by a small distance, and the sealing processes of the two chambers tend to interfere with each other. Therefore, the utility model discloses in, detect the chamber setting and collecting the intracavity, collect the chamber and detect the chamber and communicate with the external world through a common export. When the collection cavity is sealed and isolated from the outside, the detection cavity liquid can be isolated from the outside.

Since the detection chamber is located in the collection chamber, the test element placed in the detection chamber is also located in the collection chamber. The test element may be placed directly into the detection chamber, or the test element may be mounted on a carrier and placed into the detection chamber together with the carrier. The test element placed in the detection cavity needs to be fixed in position, so that the liquid sample or other external force in the detection process is prevented from impacting the test element, the test element is prevented from moving in the detection cavity, and the detection result is prevented from being influenced. The utility model discloses in, collect the chamber and include first section and second section for in the second section is located to the detection chamber of placing test element, detect chamber and second section fluid intercommunication, when first section and second section combination, first section and second section can inject test element between first section and second section.

Position limiting piece

The utility model discloses in, collect the chamber and have the locating part, the locating part is the part that is used for injecing the position of test element. The limiting part can directly limit the test element; alternatively, in the case of a test element mounted on a carrier, the limit stop limits the test element indirectly by limiting the test element carrier. The fixing of the position of the test element in the following may be the fixing of the test element itself or the fixing of the test element indirectly by fixing the test element carrier. The limiting part can be used for preventing the test element from moving up and down and also preventing the test element from toppling over into the collection cavity.

In some embodiments, the limiting member includes a fixing portion for fixing the testing element, and when the first section and the second section are combined, the fixing portion and the bottom of the detection cavity respectively abut against two ends of the testing element. The test element is fixed between the fixing portion and the bottom of the detection chamber. For example, the fixing portion abuts against the top end of the test element, and the bottom of the detection cavity abuts against the bottom end of the test element, so that the test element is prevented from moving up and down. In some embodiments, there are one, two, or more fixation portions. The distribution of the fixing parts is based on uniform stress of the test element. For example, the abutting end of the fixed part abuts against the top end of the test element, one fixed part is provided, and the contact position of the test element and the fixed part is positioned on the midline of the test element; the contact positions of the test element and the two fixing parts are symmetrical about the midline of the test element; the fixed parts are multiple, and the contact positions of the test element and the fixed parts are distributed on the test element at equal intervals.

In some embodiments, one end of the fixing portion is connected to the connecting portion, and the other end of the fixing portion is a fastening end. When the first section and the second section are combined, the abutting end of the fixing part can be positioned in the first section or extend into the second section to fix the test element.

In some forms, the stopper has a connection portion for connecting with the first segment, and the connection portion is an elastic piece. By means of the elastic piece, when the position of the testing element is limited by the limiting piece, the force applied to the testing element is elastic force. For example, when the fixing portion abuts against the test element, the fixing portion undergoes slight elastic deformation; when the fixing part is separated from the test element, the fixing part can be restored to the original position. Therefore, the limiting effect of the limiting part can be enhanced, and the damage of the limiting part to the test element is reduced.

In some embodiments, the retaining member includes a blocking portion for preventing the test element from falling into the collection chamber, the blocking portion being located between the test element and a middle portion of the second section when the test element is placed in the detection chamber and the first section and the second section are combined. In some forms, the barrier is positioned between the detection chamber and a middle portion of the second section when the test element is placed within the detection chamber and the first section and the second section are combined. So, the barrier portion can also prevent that a large amount of liquid sample from directly pouring into the detection chamber except that being used for preventing that test element from toppling over to collecting the intracavity, leads to the liquid sample to flow into the speed that detects the chamber too fast, the detection of test element in the influence detection chamber. Generally, the liquid sample should not flow into the detection chamber too fast, too fast liquid sample flow rate may cause the test element to fail, such as flood (flooding), and too fast flow rate in the sample may impact the test element or the test element carrier, resulting in movement or shaking of the test element, which may affect the detection result.

In some forms the barrier lies in a plane perpendicular to the base of the second section of the collection chamber. In some forms, the fixing portion is connected to the blocking portion, the fixing portion also lying in a plane perpendicular to the bottom of the second section of the collection chamber, and the plane in which the fixing portion lies being perpendicular to the plane in which the blocking portion lies. In some forms, the securing portion is connected to the blocking portion. In some forms, the fixing portion, the connecting portion, and the blocking portion are integrally formed.

Combination of first and second sections of a collection chamber

The first section and the second section can be detachably combined or fixedly combined. Detachable combination means that the first and second sections can be combined and then also be separated. When the test element needs to be installed or replaced, the first section and the second section are firstly separated, and the first section and the second section are combined after the test element is placed in the detection cavity. The test element can be conveniently replaced by adopting a detachable combination mode. The fixing combination mode can be welding or bonding, and the first section and the second section cannot be detached after being fixedly combined. The detachable combination or the fixed combination can be selected according to the requirement.

In some forms, the first section has a through hole for fitting outside the second section, and when the through hole of the first section is fitted outside the second section, the through hole of the first section and the second section are in clearance fit or interference fit. Preferably, the second section has an opening, and the through hole of the first section is sleeved outside the opening of the second section. The clearance fit refers to the fit with a clearance between the first section of the through hole and the second section, and the minimum clearance can be equal to zero; the first section through hole and the second section can move or be detached relatively after being in clearance fit, and the first section and the second section can be detachably combined or fixedly combined by combining other structures or processes. The interference fit refers to a fit with interference between the first section through hole and the second section, and the minimum interference can be equal to zero; when the through hole of the first section is in interference fit with the second section, the first section and the second section can be fixedly combined by using the structure of the first section and the second section or other structures or processes.

In some modes, the through hole of the first section comprises a first through hole and a second through hole, the size of the first through hole is smaller than that of the second through hole, a step is arranged between the first through hole and the second through hole, when the first section and the second section are combined, the second through hole is sleeved outside the second section, the first through hole is positioned on the second section, and the step between the first through hole and the second through hole is tightly abutted against the second section. The larger the contact area between the step between the first through hole and the second section is, the more firmly the position between the first section and the second section is defined. In order to increase the contact area between the step between the first through hole and the second section, in some modes, the second section is provided with a protrusion, when the first section and the second section are combined, the second through hole is sleeved outside the protrusion, and the step between the first through hole and the second through hole abuts against the protrusion. That is, after the protrusion is provided, the step between the first through hole and the second through hole is in contact with the protrusion of the second section, thereby increasing the contact area. In some forms, the protrusion is disposed at the second section opening. On one hand, the first section and the second section of the collecting cavity can be combined by matching the second through hole with the bulge; on the other hand, the position definition between the first section and the second section can be made more firm by increasing the contact area of the step between the first through hole and the second through hole and the protrusion.

The first section of the collection chamber needs to be connected to the cover in addition to the second section of the collection chamber in order to seal the collection chamber. In some forms the first through bore includes a threaded section and a connecting section for connecting the threaded section and the second through bore, the threaded section having an external thread on an outer wall or an internal thread on an inner wall. The device is provided with a cover body which is used for combining with the collecting cavity and forming a closed space together with the collecting cavity, the cover body can be provided with internal threads on the inner wall or external threads on the outer wall, and therefore the cover body is in threaded connection with the threaded section of the first through hole, and the combination of the cover body and the collecting cavity is achieved. The detection cavity is arranged in the collection cavity, and after the collection cavity is sealed by the cover body and isolated from the outside, the detection cavity is also sealed and isolated from the outside.

Storage chamber

In the event that a secondary test is required, the device includes a storage chamber that is removably connected to the collection chamber and is in fluid communication with the collection chamber when the storage chamber is connected to the collection chamber. In the case of having a storage chamber, a portion of the liquid sample entering the collection chamber flows into the detection chamber for primary detection, and another portion flows into the storage chamber, and is sealed by the storage chamber and transferred to another place for secondary detection. To facilitate the flow of the liquid sample from the collection chamber to the storage chamber, the junction of the storage chamber and the collection chamber is typically located at the bottom of the collection chamber.

Receiving chamber and receiving chamber opening

In order to enable the detection device to be placed horizontally, existing detection devices are often provided with a base. A common design is to provide a mechanism on the base for securing the storage chamber so that the base can be removably connected to the storage chamber. The base forms a closed space when being connected with the collecting cavity, and the storage cavity is positioned in the closed space. A disadvantage of this design is that the storage chamber cannot be separated from the base, detached from or combined with the collection chamber. The connection of the storage chamber and the collection chamber must be realized while the base is connected with the collection chamber; and the storage chamber must be detached from the collecting chamber together with the base. So, cause the operation inconvenient, the storage chamber is very easy to be connected not well, take place the weeping with the collection chamber, moreover because the interference of base, still be difficult to in time observe when the weeping appears, let alone detect the storage condition to the interior liquid sample of storage chamber. The utility model discloses in, liquid sample collection device holds the chamber including being used for holding the appearance chamber in storage chamber, holds the chamber and has the opening, when storage chamber and collection chamber combination, the storage chamber can be followed and held the chamber opening and expose.

The opening may have one of the following two functions or any combination of the following two functions. The first function is: for insertion or removal of the storage chamber from the receptacle. After the storage cavity is connected with the collecting cavity, the storage cavity is positioned in the containing cavity, and a certain distance is reserved between the storage cavity and the side wall of the containing cavity. This distance can be used for hand or tool insertion, disassembly or assembly of the storage chamber. For example, the connection or disconnection of the storage chamber to the collection chamber can be effected by: when in connection, the storage cavity is held by hand, and is put into the containing cavity through the opening and is connected with the collecting cavity; when the storage chamber is detached, a hand extends into the containing chamber from the opening, and the storage chamber is detached from the collecting chamber through the opening and taken out of the containing chamber. Can also be favorable to realizing the automation mechanized operation that storage chamber and collection chamber are connected or are dismantled through this opening, stretch into from the chamber opening through the manipulator for example and hold the chamber, with storage chamber and collection chamber dismantlement back, take out, perhaps put into from the chamber opening through the manipulator with storage chamber and hold the chamber, will store the chamber and be connected with collection chamber. The opening having the first function is the first opening described herein for insertion or removal of the storage chamber. The first opening may be located at the bottom of the cavity or at a sidewall of the cavity.

The second function is as follows: the interference of the base is avoided, and the storage condition of the liquid sample in the storage cavity is directly observed through the opening. The opening with the second aspect function is the second opening described herein for direct viewing of the storage chamber. Direct observation refers to directly observing the storage condition of the storage chamber, such as the volume of the storage chamber occupied by the liquid sample, the leakage at the connection between the storage chamber and the collection chamber, and the like, avoiding the interference of other components. For the convenience of observation, the second opening is arranged on the side wall of the cavity. There may be one, two or more second openings. When the second opening has two, two second openings can be located the different both sides that hold the chamber respectively to can select one of them of two sides to be used for observing the storage chamber, increase the convenience of observing, also can follow the storage condition of different both sides simultaneous observation storage chamber. Of course, the two second openings may also be located on the same side of the cavity. Similarly, when there are a plurality of second openings, the plurality of second openings may be located on the same side of the cavity, or may be located on different sides of the cavity.

When the opening is arranged on the side wall of the containing cavity, the opening can have two functions. For example, when the first opening is disposed on the sidewall of the cavity, the first opening has two functions.

Support piece

The support member is a member that supports the collection chamber, the storage chamber, and other components on the device. The support member typically has a support surface to allow the device as a whole to be stably placed on a table. The support member is typically located at the bottom of the collection chamber and the storage chamber is also located at the bottom of the collection chamber. The presence of the support member may cause interference with the storage chamber, making connection and disconnection of the storage chamber to the collection chamber inconvenient; the presence of the storage chamber may also result in the support member not being able to continuously provide support to the device, for example in the case of a base detachably connected to the storage chamber as described above, the removal of the storage chamber must rely on the base being detached from the collection chamber, and the base no longer providing support to the device once the storage chamber is removed, at which point the device is prone to toppling. Therefore, the utility model discloses design support piece, make support piece and collection chamber be connected to support piece and collection chamber form foretell, be used for holding the appearance chamber in storage chamber jointly. In this way, the storage chamber can be detached from or combined with the collection chamber independently of the support member, since the support member and the storage chamber are independent of each other and have no direct connection, and the support member can still provide a stable support for the entire device after the storage chamber is detached from the collection chamber.

In some forms, one end of the support member is a connecting end connected to the collection chamber and the other end of the support member is a free end, the free end enclosing a first opening of the cavity. In some forms the receptacle tapers in size from a free end of the support member to a connected end of the support member to the collection chamber. Thus, the support member forms an inverted triangular support with a small upper part and a large lower part for the device. When not holding the liquid sample in the device, owing to place test element in detecting the intracavity, so the focus of device is partial to the one side that detects the chamber place, consequently emptys to the one side that detects the chamber place easily. The inverted triangular support of the support member enables the device to be more stable and less prone to toppling when placed on a platform.

In some forms the end surface of the free end of the support member lies in a horizontal plane. The device is placed on the table top through the supporting piece, the end face of the free end of the supporting piece is in contact with the table top, and the end face is located in the horizontal plane, so that the horizontal placement of the device is facilitated.

The composition of the support member includes, but is not limited to, the following: in the first case, the support consists only of the support plate. The free end of the support plate is then the free end of the support member and the side wall of the receptacle for receiving the storage chamber is formed by the support plate and the outer wall of the collection chamber. In the second case, the support member is composed of a support plate and other members, such as a detection chamber, which protrudes outward from the bottom of the collection chamber and supports one portion of the collection chamber, and a support plate which supports the other portion of the collection chamber, so that the detection chamber and the support plate together constitute the support member. The free end of the support member and the bottom of the detection chamber together form the free end of the support member, and the side wall of the receiving chamber for receiving the storage chamber is composed of the outer wall of the detection chamber, the outer wall of the collection chamber and the support plate, as shown in fig. 3 and 4. In the third case, the support consists only of the detection chamber. The detection cavity protrudes outwards from the bottom of the collection cavity, the detection cavity is used for placing a test element, the free end of the support piece is formed at the bottom of the detection cavity, and the accommodating cavity side wall for accommodating the storage cavity is formed by the detection cavity outer wall and the collection cavity outer wall. For example, one detection cavity is arranged at the periphery of the collection cavity, and the detection cavity protrudes out of the collection cavity to form a support for the periphery of the bottom of the collection cavity; the cooperation and the detection chamber have two or more, and two or more detection chamber all are located the periphery of collecting the chamber, and two or more detection chamber protrusion form in the collecting the chamber, to the bottom formation support of collecting the chamber.

In the first case, the support consists only of the support plate. In some forms the support plate is connected to the second section of the collection chamber. In some forms the junction of the support plate and the second section is proximate the opening of the second section. In some modes, one end of the supporting plate is a connecting end connected with the collecting cavity, the other end of the supporting plate is a free end, and an opening of the free end of the supporting plate is enclosed to form a first opening of the containing cavity. In some forms, the distance between the support plate and the centerline of the collection chamber tapers from the free end of the support plate to the connected end of the support plate and the collection chamber. Thus, the support plate forms an inverted triangular support for the collection chamber. In some forms the free end of the support plate is located in a horizontal plane.

In the second case, the support consists of a support plate and a detection chamber projecting outwards from the collection chamber. One end of the supporting plate is a connecting end connected with the collecting cavity, the other end of the supporting plate is a free end, and the free end of the supporting plate and the bottom of the detection cavity jointly enclose a first opening of the containing cavity. In some embodiments, the detection chamber bottom and the free end of the support plate are located in the same horizontal plane. In the second case, the distance between the support plate and the median line of the collection chamber may also be tapered from the free end of the support plate to the end of the support plate connected to the collection chamber, as shown for example in fig. 2 and 3.

In a third case, the support consists only of a detection chamber projecting outwards from the collection chamber. In some embodiments, the bottom of the detection chamber defines a first opening. In some approaches, the bottom of the detection chamber lies in a horizontal plane.

In the first and second cases, i.e. in the case where the support member comprises a support plate, the second opening provided in the side wall of the chamber for observing the storage of the liquid sample in the storage chamber is a through hole provided in the support plate, as shown in fig. 1, for example.

Detection cavity

The detection cavity is used for placing a test element, the liquid sample flowing into the detection cavity is contacted with the test element, and the test element detects the liquid sample. The test element can be directly placed in the detection cavity, or the test element can be mounted on a carrier, and the test element and the carrier are placed in the detection cavity. The test element is placed in the detection cavity and is generally parallel to the side wall of the detection cavity, and the side wall of the detection cavity for displaying the detection result of the test element is transparent or semitransparent, and the detection progress and the detection result on the test element can be observed through the side wall. For example, the test element is a mounting plate on which a test strip is mounted, and the detection result on the test strip can be observed through the side wall of the detection chamber. Usually, when detection device level was placed, the lateral wall that the detection chamber was used for showing the testing result was perpendicular with the horizontal plane, and the platform height that is used for placing detection device often is lower, consequently before observing the testing result of test element, need pick up or incline whole detection device, can expose the test element in the sight, not only cause the observation inconvenient, leak from collecting the intracavity easily at this in-process liquid sample moreover.

The utility model discloses in, it has the lateral wall that is used for showing test element testing result to detect the chamber, the lateral wall is the acute angle with the horizontal plane, detects the chamber and is located within the acute angle. Because the side wall of the detection cavity for displaying the detection result of the test element forms an acute angle with the horizontal plane, the test element placed in the detection cavity also forms an acute angle with the horizontal plane. When the device is horizontally placed on the platform, the detection result of the test element can be observed through the side wall of the detection cavity by lowering the head, the detection device does not need to be taken up or inclined, the observation convenience is improved, and liquid leakage is reduced. In some embodiments, the side walls of the test chamber that are used to display the test results of the test element are located in a slope that intersects a horizontal plane, such as shown in fig. 2 and 3.

In some embodiments, the detection chamber is disposed within the collection chamber, and the collection chamber and the detection chamber have a common sidewall that is a sidewall for displaying the detection result of the test element, for example, as shown in fig. 2 and 3. That is, the side walls for displaying the test results of the test elements are used to define both the collection chamber and the detection chamber.

In some forms, the detection chamber is a chamber formed to protrude outwardly from the collection chamber. In some embodiments, the detection chamber is a chamber that protrudes outward from the bottom of the second section of the collection chamber, e.g., as shown in fig. 2 and 3, and the opening of the detection chamber is located at the bottom of the second section of the collection chamber. That is, the detection chamber projects outwardly from the bottom of the collection chamber not only to accommodate the test element, but also to provide support for the entire device. And because the side wall of the detection cavity for displaying the detection result of the test element forms an acute angle with the horizontal plane, the detection cavity is positioned in the acute angle, and the whole detection cavity also forms an inverted triangular support with a small upper part and a big lower part for the device. In addition, the overall dimensions of the detection chamber are greater than the dimensions of the second section of the collection chamber, such as the height. In the case of a test device, particularly a test device provided with a storage chamber, a portion of the sample in the collection chamber flows into the test chamber and is subjected to primary test, and another portion flows into the storage chamber and is transferred from the storage chamber to another place for secondary test, so that the collection chamber does not need to have a large capacity. Even in some testing devices, the large capacity of the collection chamber can result in unnecessary waste, e.g., resulting in increased overall size of the testing device, increased transportation costs, etc. The test element may have a relatively large size for the purpose of testing, for example, the test strip has a reference zone, a control zone of the test zone, etc., and these zones need to be spaced apart from each other, so that the test strip needs to have a certain length. The detection chamber formed by the outward protrusion from the bottom of the second section not only meets the requirement that the detection chamber is used for accommodating a test element, but also reduces the occupied space of the collection chamber, so that the whole structure of the device is more compact.

In some preferred forms, the bottom of the detection chamber lies in a horizontal plane. For example, the bottom of the second section of the collection chamber is located in a horizontal plane, and when the detection device is placed horizontally, the bottom of the second section is located at a level higher than the level of the bottom of the detection chamber. When the detection cavity is used for supporting the whole device, the bottom of the detection cavity forms a supporting surface. The bottom of the detection cavity is positioned in the horizontal plane, so that the total area of the supporting surface is increased, and the whole device is supported more stably.

Test element carrier

The test element is accommodated in the detection chamber, and when the liquid sample flows into the detection chamber and contacts with the test element, the test element starts to detect the substance to be analyzed in the liquid sample. The test element is typically mounted on a carrier for testing the liquid sample. Usually, the test element carrier has two or more test elements, which respectively detect different analytes, so that the carrier with two or more test elements mounted thereon can detect two or more analytes simultaneously. When a liquid sample flows in, the following problems may occur: one is that the liquid sample flowing to each test element is not uniform, which results in some test elements having completed testing and other test elements not contacting the liquid sample, which is inconvenient for observation of the testing result and may result in an extended overall testing time; the other is that the liquid sample has too high flow rate and too large amount, which may result in inaccurate or even invalid detection result of the test element, for example, for a test strip, the liquid sample flows into the detection chamber too fast, and the liquid sample rapidly passes through the mark zone and the detection zone of the test strip, so that the marker in the mark zone is greatly flushed to the detection zone, which affects the test sensitivity of the detection zone.

In some embodiments, the test element carrier has an insertion portion for insertion into the detection chamber, and the insertion portion is provided with a buffer structure for cooperating with an inner wall of the detection chamber to slow down a flow rate of the liquid sample. The buffer structure can slow down the flow rate of the liquid sample on one hand, and can keep the speed of the liquid sample flowing to each test element consistent.

In some embodiments, the buffer structure includes a baffle that forms a gap between the baffle and an inner wall of the detection chamber for the passage of the liquid sample when the insert is positioned within the detection chamber. In some embodiments, the plane of the baffle is perpendicular to the inner wall of the detection chamber when the insertion portion is inserted into the detection chamber.

In some embodiments, the left side of the baffle is flush with the left side of the test element carrier and the right side of the baffle is flush with the right side of the insert. In some embodiments, when the baffle buffers the liquid sample, the liquid sample may spread along a plane where the baffle is located, and left and right sides of the baffle are flush with left and right sides of the insertion portion, so that a time difference of the liquid sample flowing to each test element on the test element carrier is reduced, that is, the liquid sample can more uniformly flow to each test element. In some embodiments, the axis of symmetry of the baffle and the centerline of the test element carrier are collinear.

In some embodiments, a baffle is disposed on a back side of the test element carrier. The side of the carrier for mounting the test element is the front side of the test element carrier, and the side opposite to the front side is the back side of the test element carrier. To facilitate the observation of the test results, the front side of the test element carrier often faces the side wall of the test cavity for displaying the test results. Thus, the liquid sample flowing into the detection chamber first flows through the gap between the back surface of the test element carrier and the detection chamber, then flows through the gap between the bottom of the test element carrier and the detection chamber, and finally remains until the front surface of the test element carrier contacts the test element. The baffle is arranged on the back surface of the test element carrier, so that the liquid sample is buffered before being contacted with the test element, and the baffle can be prevented from interfering the installation of the test element.

In some embodiments, the barrier has two or more blocks, and the two or more blocks have a height difference when the insertion portion is located in the detection chamber; the size of the gap between the baffle and the inner wall of the detection cavity is gradually reduced along with the increase of the height of the baffle. In this manner, the two or more baffles create a multi-layer buffer for the liquid sample.

In some embodiments, the buffer structure further includes a support portion disposed at a bottom end of the insertion portion, and a channel for slowing down a flow rate of the liquid sample is formed between the support portion and a bottom of the detection chamber when the insertion portion is inserted into the detection chamber. The support part is used for supporting the whole test element carrier. The bottom end of the insertion portion refers to an end of the insertion portion near the bottom of the detection chamber when the insertion portion is located in the detection chamber. The liquid sample flows slowly through the channel from the back side of the test element carrier to the front side of the test element carrier and contacts the test element mounted to the front side of the test element carrier.

In some modes, the supporting part comprises a blocking sheet, one end of the blocking sheet is connected with the inserting part, the other end of the blocking sheet is a free end, and the channel is formed between the end face of the free end of the blocking sheet and the bottom of the detection cavity. The distance between the bottom end of the insertion part and the bottom of the detection cavity is reduced by the blocking sheet, and the flow speed of the liquid sample is reduced under the blocking action of the blocking sheet when the liquid sample passes through the detection cavity.

In some embodiments, when the insertion portion is inserted into the detection chamber, an angle is formed between the end surface of the free end of the blocking sheet and the bottom of the detection chamber, and the opening of the angle faces the direction opposite to the flowing direction of the liquid sample. That is, the end face of the free end of the blocking piece is an inclined plane, so that the size of a channel formed between the blocking piece and the bottom of the detection cavity is gradually reduced towards the flowing direction of the liquid sample, and the flow speed of the liquid sample is reduced when the liquid sample passes through the channel.

In some forms the support portion includes a projection for supporting the test element carrier, the projection having a contact surface for contacting the bottom of the detection chamber, the end surface of the free end of the blocking piece being located above the contact surface when the insertion portion is inserted into the detection chamber. In some forms, the projection has a free end, and an end surface of the free end includes a contact surface and a slope intersecting the contact surface, the slope lying in the same plane as the free end surface of the blocking tab.

The utility model discloses in, it is the chamber that forms from collecting the outside protrusion in chamber bottom to detect the chamber to collect chamber fluid intercommunication. Due to the communication effect, the liquid level in the collection chamber is as high as the liquid level in the detection chamber. When a large volume of liquid sample is collected, the test element is largely immersed in the liquid sample, which may cause the test element to fail. For example, the test element is a test strip having a detection zone, a reference zone, and a control zone, and the liquid sample is normally wicked through the zones in order to perform a proper test. However, when the liquid sample is large, the test strip cannot perform detection when the areas are immersed in the liquid sample at the same time. In practice, in order to avoid the liquid sample from being too much and cause the failure of the test element, a film can be covered on the surface of the test element carrier, so that the film and the groove form a cavity with one open end. The testing element sucks the liquid sample from the opening of the cavity, on one hand, the thin film isolates the liquid sample from the testing element, and the testing element is prevented from being soaked in the liquid sample; on the other hand, the film and the groove form a cavity, and a certain air pressure is arranged in the cavity, so that the air pressure prevents excessive liquid samples entering the cavity through the cavity opening, and the test element cannot lose efficacy when the liquid samples are excessive.

Detailed Description

The present invention will be described in further detail with reference to specific embodiments.

A device for collecting and testing a liquid sample, for example as shown in fig. 1 and 2, comprises a collection chamber for collecting the liquid sample, the collection chamber comprises a first section 101 and a second section 102, the second section 102 is a cavity, and the second section 102 is provided with a testing chamber 2 for placing a testing element therein. The detection chamber 2 is in fluid communication with the second section 102, the first section 101 and the second section 102 being capable of confining a test element between the first section 101 and the second section 102 when the first section 101 and the second section 102 are combined, such as shown in fig. 2. The limiting part can directly limit the test element; alternatively, in the case where the test element is mounted on a carrier, the limiting member indirectly limits the test element by limiting the test element carrier 5, as shown in fig. 2, the test element is a test strip, the test strip is mounted on a mounting plate, and the limiting member limits the test strip mounting plate, thereby indirectly detecting the position of the test strip. The definition of the position of the test element in the following may be the definition of the test element itself or the indirect definition of the test element by defining the test element carrier.

Position limiting piece

In some embodiments, as shown in fig. 3 and 4, the first segment 101 has a position limiter for limiting the position of the test element, and the position limiter includes a fixing portion 301 for fixing the test element, and when the first segment 101 and the second segment 102 are combined, the fixing portion 301 and the bottom portion of the detection cavity respectively abut against two ends of the test element. The test element is fixed between the fixing portion and the bottom of the detection chamber. There may be one, two or more fixing portions, for example, as shown in fig. 6.

In some embodiments, as shown in fig. 3 and 4, the fixing portion 301 has a fastening end 3011 for fastening the test element, and the fastening end 3011 is located in the second section when the first section and the second section are combined.

In some embodiments, as shown in fig. 3 to 5, the position-limiting member has a connecting portion 302 for connecting with the first segment, and the connecting portion 302 is an elastic sheet. With the help of the elastic sheet, when the position of the test element is limited by the limiting part, the force applied to the test element is elastic force, so that the limiting effect of the limiting part can be enhanced, and the damage of the limiting part to the test element is reduced.

In some embodiments, one end of the fixing portion 301 is connected to the connecting portion 302, and the other end of the fixing portion 302 is a fastening end 3011, as shown in fig. 3 and 4.

In some embodiments, the stop comprises a stop 303 for preventing the test element from falling into the collection chamber, the stop 303 being located between the test element and the middle of the second section when the test element is placed in the detection chamber 2 and the first section 101 and the second section 102 are combined, as shown in fig. 4. When the test element is placed in the detection chamber 2, the first section 101 and the second section 102 are combined, the blocking portion 303 is located between the detection chamber 2 and the middle of the second section.

In some embodiments, one end of the blocking portion 303 is connected to the connecting portion 302 and the other end of the blocking portion 303 is a free end, for example, as shown in fig. 3 and 4. The barrier free end 3031 is located within the second segment when the first segment 101 and the second segment 102 are combined. The free end 3031 of the blocking part is close to the bottom of the second section relative to the abutting end 3011 of the fixing part. That is, the free end of the blocking portion is located below the abutting end of the fixing portion. A fixed part in the limiting part,

Combination of first and second sections of a collection chamber

In some embodiments, such as shown in fig. 1 and 2, the second section 102 of the collection chamber has an opening, the first section 101 has a through hole for fitting outside the second section, and when the through hole of the first section 101 is fitted outside the opening of the second section 102, the through hole of the first section and the second section are in a clearance fit or interference fit. The limiting member is disposed on an inner wall of the through hole of the first segment 101, as shown in fig. 4 and 5. The limiting member is connected with the inner wall of the through hole of the first section 101 through the connecting part 302.

In some embodiments, such as shown in fig. 3 and 4, the through hole of the first section 101 includes a first through hole 1011 and a second through hole 1012, the size of the first through hole 1011 is smaller than the size of the second through hole 1012, a step is provided between the first through hole 1011 and the second through hole 1012, when the first section 101 and the second section 102 are combined, the second through hole 1012 is sleeved outside the second section 102, the first through hole 1011 is located on the second section 102, and the step between the first through hole 1011 and the second through hole 1012 abuts against the second section 102. When the first and second sections are combined, the relative position between the first and second sections may be defined by a step between the first and second through holes. The limiting member is disposed on the inner wall of the first through hole 1011.

In some embodiments, such as shown in fig. 7 and 8, the second section 102 is provided with a protrusion 1021, and when the first section 101 and the second section 102 are combined, the second through hole 1012 is sleeved on the protrusion, and the step between the first through hole 1011 and the second through hole 1012 abuts against the protrusion.

In some embodiments, second section 102 has an opening, and protrusion 1021 is disposed at the opening of second section 102. In some embodiments, such as shown in fig. 3 and 4, the first through hole 1011 includes a threaded section 1011-1 and a connecting section 1011-2 for connecting the threaded section and the second through hole, and the threaded section 1011-1 is provided with an external thread on the outer wall or an internal thread on the inner wall. The device has a cover 6 for combining with the collection chamber, forming a closed space together with the collection chamber, as shown in fig. 1 and 2, the cover 6 may be provided with an internal thread on the inner wall or an external thread on the outer wall, so that the cover 6 is in threaded connection with the threaded section 1011-1 of the first through hole, thereby achieving the combination of the cover and the collection chamber.

Receiving chamber and receiving chamber opening

In some embodiments, the device comprises a collection chamber for collecting the liquid sample and a storage chamber 3, the collection chamber and storage chamber 3 being removably combined, the device having a receptacle for receiving the storage chamber, the receptacle having an opening through which the storage chamber can be exposed when the storage chamber is combined with the collection chamber.

In some embodiments, the receptacle openings include a first opening 801 for insertion or removal of the storage chamber and a second opening 802 for direct viewing of the storage chamber, such as shown in FIG. 13. In other embodiments, the cavity opening may comprise a first opening or a second opening.

In some embodiments, one end of the cavity is connected to the collection chamber and the first opening 801 is at the other end of the cavity, as shown, for example, in FIG. 13. In other embodiments, the first opening may be a through hole formed in a sidewall of the cavity.

In some embodiments, the second opening 802 is a through hole disposed in a sidewall of the cavity. The through-hole may be, for example, in the form shown in fig. 13, i.e., the through-hole is a through-hole formed concavely from the free end of the support plate toward the support plate and communicating with the first opening; alternatively, the through-hole may be a hole on the support plate that does not communicate with the first opening. There are two second openings 802. when the storage chamber is combined with the collection chamber, the two second openings 802 are located on either side of the storage chamber.

Support piece

In some embodiments, the device has a support member for supporting the collection chamber, the support member being connected to the collection chamber, the support member and the collection chamber together forming a receptacle for receiving the storage chamber, for example as shown in figures 1 to 4.

In some embodiments, one end of the support member is a connection end connected to the collection chamber, and the other end of the support member is a free end, the free end of the support member enclosing said first opening. The receptacle is tapered in size from the free end of the support member to the connecting end of the support member to the collection chamber. The end surface of the free end of the support member is located in a horizontal plane.

In some embodiments, the support member comprises a detection chamber 2 and a support plate 7, the detection chamber 2 is a chamber formed by protruding from the collection chamber, for example, as shown in fig. 1-4, the support plate 7 is connected to the second section 102 of the collection chamber, and the connection between the support plate 7 and the second section 102 of the collection chamber is close to the opening of the second section. The supporting plate, the outer wall of the collecting cavity and the outer wall of the detection cavity are enclosed to form a containing cavity, and the side wall of the containing cavity comprises the supporting plate 7, the outer wall of the collecting cavity and the outer wall of the detection cavity 2.

In some embodiments, such as those shown in FIGS. 1-4, one end of the support plate 7 is connected to the collection chamber 1 and the other end of the support plate 7 is a free end 701. The free end 701 of the support plate is located in a horizontal plane. The free end 701 of the support plate is located in the same horizontal plane as the bottom of the detection chamber 2. The second opening 802 is a through hole provided in the support plate 7.

In some embodiments, the support may also consist only of the detection chamber projecting outwardly from the collection chamber, or the support may consist only of the support plate.

Detection cavity

In some embodiments, such as shown in fig. 3 and 4, a detection chamber 2 for placing a test element is provided in the second collection chamber segment 102, and the second collection chamber segment 102 is in fluid communication with the detection chamber 2. The detection cavity 2 is provided with a side wall 201 for displaying the detection result of the test element, the side wall 201 and the horizontal plane form an acute angle, and the detection cavity 2 is positioned in the acute angle. When the device level was placed on the platform, need not to take up or slope detection device and can see through the lateral wall that detects the chamber and observe the testing element's testing result, increased the convenience of observing, reduced the weeping. The sidewall 201 lies in a plane that intersects the horizontal plane.

In some embodiments, such as shown in fig. 3 and 4, the detection chamber 2 and the second section 102 of the collection chamber have a common sidewall, which is a sidewall 201 for displaying the test element detection results. That is, the side walls for displaying the test element test results are used to enclose both the second section of the collection chamber and the test chamber.

In some embodiments, the detection chamber 2 is a chamber formed by protruding from the bottom of the second section 102 of the collection chamber, and the opening of the detection chamber 2 is located at the bottom of the second section 102 of the collection chamber. The detection chamber is not only used for accommodating the test element, but also constitutes a support for supporting the collection chamber. That is, the detection chamber projects outwardly from the bottom of the collection chamber not only to accommodate the test element, but also to provide support for the entire device.

In some embodiments, such as shown in fig. 3 and 4, the bottom of the detection chamber 2 is located in a horizontal plane.

Test element carrier

In some embodiments, the test element carrier 5 has an insertion portion for insertion into the detection chamber, as shown for example in fig. 9, the insertion portion being provided with a buffer structure for cooperating with the inner wall of the detection chamber, slowing down the flow rate of the liquid sample. The cushioning structure is shown, for example, in fig. 10 and includes a baffle 501. When the insertion portion is positioned in the detection chamber, a gap for passing the liquid sample is formed between the baffle 501 and the inner wall of the detection chamber 2. When the insertion portion is inserted into the detection chamber, the plane on which the baffle 501 is located is perpendicular to the inner wall of the detection chamber 2. The insertion portion refers to a portion of the test element carrier inserted into the detection chamber.

In some embodiments, such as shown in FIG. 10, the left side 5011 of the bezel is flush with the left side of the test element carrier and the right side 5012 of the bezel is flush with the right side of the insert. The axis of symmetry of the baffle and the centerline of the test element carrier are in the same line.

In some embodiments, such as shown in FIG. 10, a baffle 501 is provided on the back side of the test element carrier 5. The side of the carrier for mounting the test element is the front side of the test element carrier, and the side opposite to the front side is the back side of the test element carrier.

In some embodiments, such as shown in FIG. 10, there are two baffles 501, and there is a height difference between the two baffles 501 when the insert is located in the detection chamber; the size of the gap between the baffle 501 and the inner wall of the detection chamber 2 is gradually reduced as the height of the baffle 8 is increased. In some embodiments, the baffles may be provided in multiple pieces, and when the insertion portion is located in the detection cavity, the multiple pieces of baffles have a height difference therebetween; the size of the gap between the baffle and the inner wall of the detection cavity is gradually reduced along with the increase of the height of the baffle.

In some embodiments, the buffer structure further comprises a support portion disposed at the bottom end of the insertion portion, and a channel for slowing down the flow rate of the liquid sample is formed between the support portion and the bottom of the detection chamber when the insertion portion is inserted into the detection chamber. The support part is used for supporting the whole test element carrier. The bottom end of the insertion portion refers to an end of the insertion portion near the bottom of the detection chamber when the insertion portion is located in the detection chamber. The liquid sample flows slowly through the channel from the back side of the test element carrier to the front side of the test element carrier and contacts the test element mounted to the front side of the test element carrier. In some embodiments, such as shown in fig. 10 and 11, the support portion comprises a blocking tab 502, one end of the blocking tab 502 is connected to the insertion portion, the other end of the blocking tab 502 is a free end, and the channel is formed between an end face 5021 of the free end of the blocking tab and the bottom of the detection chamber 2. The distance between the bottom end of the insertion part and the bottom of the detection cavity is reduced by the blocking sheet, and the flow speed of the liquid sample is reduced under the blocking action of the blocking sheet when the liquid sample passes through the detection cavity.

In some embodiments, the end face 5021 of the free end of the barrier tab forms an angle with the bottom of the detection chamber 2 when the insert is inserted into the detection chamber 2, and the opening of the angle faces in the opposite direction to the flow of the liquid sample. That is, the end face of the free end of the blocking piece is an inclined plane, so that the size of a channel formed between the blocking piece and the bottom of the detection cavity is gradually reduced towards the flowing direction of the liquid sample, and the flow speed of the liquid sample is reduced when the liquid sample passes through the channel.

In some embodiments, the support portion comprises a bump 503 for supporting the test element carrier, the bump 503 having a contact face 5031 for contacting the bottom of the detection chamber, the end face 5021 of the free end of the stop tab being located above the contact face 5031 when the insert is inserted into the detection chamber.

In some embodiments, such as shown in FIG. 12, the bump 503 has a free end, and the end surface of the free end includes a contact surface 5031 and a slope 5032 intersecting the contact surface, the slope 5032 is in the same plane as the end surface 5021 of the free end of the barrier.

The embodiments described in this specification are merely illustrative of implementations of the inventive concepts, and the scope of the invention should not be considered limited to the specific forms set forth in the embodiments, but rather the scope of the invention is intended to include equivalent technical means as would be understood by those skilled in the art from the inventive concepts.

Claims

1. A liquid sample collection device comprises a collection cavity and a storage cavity, wherein the collection cavity and the storage cavity are used for collecting liquid samples and are detachably combined, and the liquid sample collection device is characterized in that: the device has a cavity for receiving the storage chamber, the cavity having an opening, the storage chamber being capable of being exposed from the cavity opening when the storage chamber is combined with the collection chamber.

2. The apparatus of claim 1, wherein: the chamber opening includes a first opening for insertion or removal of the storage chamber and/or a second opening for direct viewing of the storage chamber.

3. The apparatus of claim 2, wherein: one end of the cavity is connected with the collecting cavity, and the first opening is positioned at the other end of the cavity; or the first opening is a through hole arranged on the side wall of the accommodating cavity.

4. The apparatus of claim 2 or 3, wherein: the second opening is a through hole arranged on the side wall of the containing cavity.

5. The apparatus of claim 4, wherein: the at least one second opening may be located on one, both or more sides of the storage chamber when the storage chamber is combined with the collection chamber.

6. The apparatus of claim 2, wherein: the device is provided with a supporting piece for supporting the collecting cavity, the supporting piece is connected with the collecting cavity, and the supporting piece and the collecting cavity form the containing cavity together.

7. The apparatus of claim 6, wherein: one end of the supporting piece is a connecting end connected with the collecting cavity, the other end of the supporting piece is a free end, and the free end of the supporting piece is enclosed to form the first opening.

8. The apparatus of claim 7, wherein: the receptacle is tapered in size from the free end of the support member to the connecting end of the support member to the collection chamber.

9. The apparatus of claim 7 or 8, wherein: the end surface of the free end of the support member is located in a horizontal plane.

10. The apparatus of claim 9, wherein: the support member includes a support plate, and the second opening is located on the support plate.