CN210163436U - Nucleic acid draws appearance with dividing apart from device - Google Patents
Nucleic acid draws appearance with dividing apart from device Download PDFInfo
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- CN210163436U CN210163436U CN201920425953.0U CN201920425953U CN210163436U CN 210163436 U CN210163436 U CN 210163436U CN 201920425953 U CN201920425953 U CN 201920425953U CN 210163436 U CN210163436 U CN 210163436U
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Abstract
The utility model relates to a nucleic acid draws appearance with dividing apart from device, comprising a base plate, divide apart from the board, reciprocating device, elevating gear and bar magnet subassembly, the vertical lead screw fixed plate that is fixed with in both ends of bottom plate one side, the surface of lead screw fixed plate is equipped with linear guide, sliding connection has first slider on linear guide's the outside, first slider and the both ends fixed connection who divides apart from the board, the guiding hole has been seted up to the inside of dividing apart from the board, divide apart from one side of board to be provided with reciprocating device, the middle level of bottom plate is provided with horizontal slide rail, the outside sliding connection of horizontal slide rail has the second slider, second slider and bar magnet subassembly fixed connection, the top of bottom plate is provided with elevating gear, elevating gear is connected with the transmission of bar magnet subassembly. The utility model discloses an it divides apart from the upper and lower high distance of board on the bottom plate to reciprocate the device regulation, and then carries out even branch apart from each bar magnet of connecting bar magnet subassembly bottom, realizes the work of transferring the target object from bulky reaction system to little volume reaction system.
Description
Technical Field
The utility model relates to an automatic change nucleic acid and draw technical field, especially relate to a nucleic acid extraction is minute apart from device for appearance.
Background
Nucleic acid extraction is the basis of many biological experiments, and the nucleic acid extractor is selected by more and more people as an automatic high-flux instrument at present. The reaction system of the existing nucleic acid extraction instrument is generally below 1ml, but in many experiments, a reaction system with a large component is needed when trace nucleic acid needs to be extracted from a sample, and a reaction system with a small component is needed in the subsequent experiment operation process, so that a magnetic rod frame capable of changing the distance between magnetic rods is needed in the experiment to complete the work of transferring a target object from a large-volume reaction system to a small-volume reaction system, and the existing market does not have similar products.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to provide a nucleic acid draws appearance with dividing apart from device adjusts the upper and lower high distance of minute distance board on the bottom plate through reciprocating device, and then carries out even minute distance to each bar magnet that bar magnet subassembly bottom is connected, cuts apart the distance between each adjacent two of bar magnet for the same, realizes the work of transferring the target object from bulky reaction system to little volume reaction system, improves the work efficiency of biology experiment.
In order to achieve the above purpose, the technical scheme of the utility model is as follows:
a nucleic acid extraction is apart from device for appearance, including bottom plate, minute distance board, up-and-down moving device, elevating gear and bar magnet subassembly, the bottom plate is vertical to be set up, the both ends of bottom plate one side are vertical to be fixed with the lead screw fixed plate, bottom one side of lead screw fixed plate is installed first photoelectric switch, the surface of lead screw fixed plate is equipped with linear guide, the outside sliding connection of linear guide has first slider, first slider and minute distance board's both ends fixed connection, the inside of minute distance board is seted up the guiding hole, minute distance board is far away from one side of bottom plate and is equipped with up-and-down moving device, the centre level of bottom plate is provided with horizontal slide rail, horizontal slide rail and lead screw fixed plate are located the same side of bottom plate, the outside sliding connection of horizontal slide rail has the second slider, the second slider and bar magnet subassembly fixed connection, the top of bottom plate is provided with, the magnetic rod assembly is arranged at the bottom of the lifting device, and the lifting device is in transmission connection with the magnetic rod assembly.
In the above scheme, at least one first sliding block is arranged on the linear guide rail on each side, the back of the first sliding block is fixedly connected with the two ends of the distance-dividing plate respectively, at least one transverse sliding rail is arranged, the second sliding blocks are uniformly arranged on each transverse sliding rail, and the back of each second sliding block is fixedly connected with the magnetic rod assembly respectively.
In the above scheme, at least two guide holes are arranged, and the hole center distances between two adjacent guide holes on the same horizontal plane are the same.
In the above scheme, the up-down moving device comprises a first motor fixing plate, a first synchronizing wheel, a screw rod supporting seat and a second synchronizing wheel, the first motor fixing plate is installed on one side of the bottom plate far away from the distance separating plate, the bottom of the first motor fixing plate is provided with a stepping motor, an output shaft of the stepping motor penetrates through the top of the first motor fixing plate and is fixedly connected with the first synchronizing wheel, the screw rod supporting seat is fixed at the upper end and the lower end of the screw rod fixing plate on one side of the bottom plate, a ball screw rod is arranged in the screw rod supporting seat, a screw rod nut seat is arranged in the middle of the ball screw rod and is connected with one end side face of the distance separating plate through a nut, the top of the ball screw rod penetrates through the top of the screw rod supporting seat and is fixedly connected with the second synchronizing wheel, and the second synchronizing.
In the above scheme, elevating gear includes the second motor fixed plate, top fixed connection in the middle of one end of second motor fixed plate and the bottom plate, the second photoelectric switch is installed to one side of second motor fixed plate, the lead screw motor is installed at the top of second motor fixed plate, the output shaft of lead screw motor passes through the ring flange and is connected with the transmission of bar magnet subassembly.
In the above scheme, the bar magnet subassembly is provided with two sets ofly at least, the bar magnet subassembly includes bar magnet, bearing frame, rotates and ties and linking bridge, the spout has been seted up to the inside of bearing frame, it sets up inside the spout to rotate the bolt, linking bridge is through rotating bolt and spout and bearing frame swing joint, the bar magnet sets up the bottom at linking bridge, the swing joint of linking bridge and bar magnet.
In the above scheme, the linking bridge includes first slider connecting rod, second slider connecting rod and third slider connecting rod, first slider connecting rod is located directly over the second slider connecting rod, one side fixed connection of first slider connecting rod and second slider connecting rod, its link and third slider connecting rod fixed connection, third slider connecting rod one side and second slider fixed connection, gyro wheel and the minute distance plate roll connection of third slider connecting rod opposite side installation through the guiding hole, be provided with the bar magnet fixed axle between the opposite side of first slider connecting rod and second slider connecting rod, the axle center fixed connection of first slider connecting rod and rotation bolt is run through at the top of bar magnet fixed axle, second slider connecting rod and bar magnet swing joint are run through to the bottom of bar magnet fixed axle.
Compared with the prior art, the beneficial effects of the utility model are that: the vertical height distance of the distance separating plate on the bottom plate is adjusted through the up-and-down moving device, then each magnetic rod connected to the bottom of the magnetic rod assembly is uniformly separated, one side of the third sliding block connecting rod is connected with the distance separating plate in a rolling manner through a roller arranged in the guide hole, the up-and-down moving route of the connecting support is guided through the guide hole in the distance separating plate, and the distance between two adjacent magnetic rod assemblies is conveniently divided into equal parts. The distance between two adjacent magnetic rods is divided to be the same, so that the work of transferring the target object from a large-volume reaction system to a small-volume reaction system is realized, and the work efficiency of a biological experiment is improved.
Drawings
FIG. 1 is a front view of the overall structure of the present invention;
FIG. 2 is a side view of the overall structure of the present invention;
FIG. 3 is a top view of the overall structure of the present invention;
FIG. 4 is a perspective view of the overall structure of the present invention;
FIG. 5 is a front view of the overall structure of the bar magnet assembly of the present invention;
FIG. 6 is a side view of the overall structure of the bar magnet assembly of the present invention;
FIG. 7 is a top view of the overall structure of the bar magnet assembly of the present invention;
FIG. 8 is a perspective view of the overall structure of the middle bar magnet assembly of the present invention;
fig. 9 is a schematic diagram of the structure of the middle partition board of the present invention.
Reference numbers in the figures: 1-a bottom plate; 11-screw rod fixing plate; 12-a first opto-electronic switch; 13-a linear guide rail; 14-a first slide; 15-transverse slide rail; 16-a second slide; 2-a pitch plate; 21-a pilot hole; 3-up-down moving means; 31-a first motor fixing plate; 32-a stepper motor; 33-a first synchronizing wheel; 34-a screw rod supporting seat; 35-ball screw; 36-a lead screw nut seat; 37-a second synchronizing wheel; 38-a synchronous belt; 4-a lifting device; 41-a second motor fixing plate; 42-a second opto-electronic switch; 43-a screw motor; 44-flange plate; 5-a magnetic bar assembly; 51-a magnetic bar; 52-a bearing seat; 53-a first sliding connecting rod; 54-a second sliding connecting rod; 55-a third sliding connecting rod; 56-magnetic rod fixing shaft; 57-rotating the bolt; 58-chute; 59-connecting the stent.
Detailed Description
The technical solution of the present invention will be further described in detail with reference to the accompanying drawings and embodiments.
As shown in fig. 1 to 4, a nucleic acid extraction is a distance-dividing device for appearance, including bottom plate 1, distance-dividing plate 2, up-down moving device 3, elevating gear 4 and bar magnet subassembly 5, bottom plate 1 is the rectangular plate, and vertical setting, the both ends of bottom plate 1 one side are vertically fixed with lead screw fixed plate 11, first photoelectric switch 12 is installed to bottom one side of lead screw fixed plate 11, the surface of lead screw fixed plate 11 is equipped with linear guide 13, linear guide 13's model is SEB10-135x, the outside sliding connection of linear guide 13 has first slider 14, its model is SEB10-135h, first slider 14 and distance-dividing plate 2's both ends fixed connection.
Referring to fig. 9, the partition plate 2 is provided with at least two guide holes 21 therein, and the distance between the centers of two adjacent guide holes 21 on the same horizontal plane is the same. That is, as shown in fig. 9, six guide holes 21 are formed, and the horizontal center distances d of two adjacent guide holes 21 are the same, so that the guide holes 21 are generally inclined holes and generally have a symmetrical structure.
The up-down moving device 3 is arranged on one side, far away from the bottom plate 1, of the distance separating plate 2, the up-down moving device 3 comprises a first motor fixing plate 31, a first synchronizing wheel 33, a lead screw supporting seat 34 and a second synchronizing wheel 37, the types of the first synchronizing wheel 33 and the second synchronizing wheel 37 are HTPA20S5M100-A-P8, the first motor fixing plate 31 is installed on one side, far away from the distance separating plate 2, of the bottom of the first motor fixing plate 31, a stepping motor 32 is installed at the bottom of the first motor fixing plate 31, the type of the stepping motor is a two-phase four-wire stepping motor of YK57XQ76-833A, and the stepping motor 32 is electrically connected with an external power supply through a first photoelectric switch. An output shaft of the stepping motor 32 penetrates through the top of the first motor fixing plate 31 to be fixedly connected with the first synchronizing wheel 33, the lead screw supporting seat 34 is fixed at the upper end and the lower end of the lead screw fixing plate 11 on one side, a ball screw 35 with the model number of SFU1204-100 is arranged inside the lead screw supporting seat 34, a lead screw nut seat 36 is arranged in the middle of the ball screw 35, and the lead screw nut seat 36 is connected with one end side face of the distance separating plate 2 through a nut. The top of the ball screw 35 penetrates the top of the screw support base 34 and is fixedly connected with the second synchronous wheel 37, and the second synchronous wheel 37 is in transmission connection with the first synchronous wheel 33 through a synchronous belt 38. The vertical height distance of the distance separating plate 2 on the bottom plate 1 is adjusted through the up-down moving device 3, and then the uniform distance separation is carried out on each magnetic rod 51 connected with the bottom of the magnetic rod assembly 5.
The middle of the bottom plate 1 is horizontally provided with a transverse slide rail 15, the type of the transverse slide rail 15 is SEB8-130, the transverse slide rail 15 and the screw rod fixing plate 11 are positioned on the same side of the bottom plate 1, the outer side of the transverse slide rail 15 is connected with a second slide block 16 in a sliding mode, the structure of the second slide block 16 is the same as that of the first slide block 14, the second slide block 16 is fixedly connected with one side of the magnetic rod assembly 5, and the moving sub-distance size distance of the magnetic rod assembly 5 is determined by the position of the second slide block 16.
The lifting device 4 is arranged at the top of the bottom plate 1, the lifting device 4 comprises a second motor fixing plate 41, one end of the second motor fixing plate 41 is fixedly connected with the middle top of the bottom plate 1, a second photoelectric switch 42 is installed at one side of the second motor fixing plate 41, the first photoelectric switch 12 of the second photoelectric switch 42 is identical in structure, a lead screw motor 43 is installed at the top of the second motor fixing plate 41 and is 42-2110 in type, the lead screw motor 43 is electrically connected with an external power supply through the second photoelectric switch 42, and an output shaft of the lead screw motor 43 is in transmission connection with the magnetic bar assembly 5 through a flange plate 44. The magnetic rod assembly 5 is arranged at the bottom of the lifting device 4, and the lifting device 4 is in transmission connection with the magnetic rod assembly 5. The magnetic rod 51 at the bottom of the magnetic rod assembly 5 is pressed into each test tube by the lifting device 4, and then a trace amount of nucleic acid is extracted from the sample.
In the above embodiment, at least one first sliding block 14 is disposed on each side of the linear guide 13, the back of the first sliding block is fixedly connected to the two ends of the distance-dividing plate 2, at least one transverse sliding rail 15 is disposed, the second sliding blocks 16 are uniformly disposed on each transverse sliding rail 15, and the back of the second sliding blocks is fixedly connected to the magnetic rod assembly 5. As shown in fig. 1 to 4, two first sliding blocks 14 are arranged on the linear guide 13 on each side, the back parts of the first sliding blocks are fixedly connected with the upper end and the lower end of the distance-dividing plate 2, two transverse sliding rails 15 are arranged, six second sliding blocks 16 are uniformly arranged on each transverse sliding rail 15, and the back parts of the second sliding blocks are fixedly connected with the magnetic rod assemblies 5.
As shown in fig. 5 to 8, at least two sets of magnetic rod assemblies 5 are provided, each magnetic rod assembly 5 comprises a magnetic rod 51, a bearing seat 52, a rotating bolt 57 and a connecting bracket 59, a sliding groove 58 is formed in the bearing seat 52, the rotating bolt 57 is arranged in the sliding groove 58, and the connecting bracket 59 is movably connected with the bearing seat 52 through the rotating bolt 57 and the sliding groove 58, so that the magnetic rod assemblies 5 can change along with the distance change on the distance separating plate 2, and the magnetic rods 51 can be kept in a vertical installation state due to the arrangement of the rotating bolt 57. The magnetic rod 51 is arranged at the bottom of the connecting bracket 59, and the connecting bracket 59 is in clamping connection or threaded connection with the magnetic rod 51.
In the above scheme, the connecting bracket 59 includes the first slider connecting rod 53, the second slider connecting rod 54 and the third slider connecting rod 55, the first slider connecting rod 53 is located right above the second slider connecting rod 54, the first slider connecting rod 53 is fixedly connected with one side of the second slider connecting rod 54, and the connecting end thereof is fixedly connected with the third slider connecting rod 55, so as to form an irregular U-shape, thereby facilitating the bypassing of the bottom of the distance plate 2. One side of a third slider connecting rod 55 is fixedly connected with the second slider 16, the other side of the third slider connecting rod 55 is in rolling connection with the distance-dividing plate 2 through a roller arranged in the guide hole 21, and the up-and-down moving route of the connecting bracket 59 is guided by the guide hole 21 in the distance-dividing plate 2, so that the distance between two adjacent magnetic rod assemblies 5 is conveniently divided into equal distances. Be provided with bar magnet fixed axle 56 between the opposite side of first slider connecting rod 53 and second slider connecting rod 54, the top of bar magnet fixed axle 56 runs through first slider connecting rod 53 and rotates the axle center fixed connection of bolt 57, bar magnet fixed axle 56 and first slider connecting rod 53 swing joint, the bottom of bar magnet fixed axle 56 runs through second slider connecting rod 54 and bar magnet 51 swing joint, is convenient for be convenient for impress the bar magnet 51 of bar magnet subassembly 5 bottom in each test tube through elevating gear 4.
The distance division process: the first photoelectric switch 12 is turned on, the stepping motor 32 is started, the first synchronous wheel 33 starts to rotate to drive the second synchronous wheel 37 and the ball screw 35 to rotate, the ball screw nut seat 36 is connected with the distance division plate 2 and the first sliding block 14, the ball screw 35 rotates to drive the distance division plate 2 to move up and down on the surface of the linear guide rail 13, each magnetic bar assembly 5 is driven to perform distance division through the rolling of the guide hole 21 and a roller installed in the guide hole 21, the second photoelectric switch 42 is turned on, the screw motor 43 is started to drive the magnetic bar 51 to move up and down, and the distance division process of the magnetic bar fixing shaft 56 is completed.
The above-mentioned embodiments further explain in detail the objects, technical solutions and advantages of the present invention, and it should be understood that the above-mentioned embodiments are only the embodiments of the present invention, and are not intended to limit the scope of the present invention, any modifications, equivalent replacements, improvements, etc. made within the spirit and principle of the present invention should be included within the scope of the present invention.
Claims (7)
1. A nucleic acid extraction is distancing device for appearance which characterized in that: the magnetic rod lifting device comprises a bottom plate (1), a distance separating plate (2), an up-down moving device (3), a lifting device (4) and a magnetic rod assembly (5), wherein the bottom plate (1) is vertically arranged, two ends of one side of the bottom plate (1) are vertically fixed with a lead screw fixing plate (11), one side of the bottom of the lead screw fixing plate (11) is provided with a first photoelectric switch (12), the outer surface of the lead screw fixing plate (11) is provided with a linear guide rail (13), the outer side of the linear guide rail (13) is in sliding connection with a first sliding block (14), the first sliding block (14) is fixedly connected with two ends of the distance separating plate (2), a guide hole (21) is formed in the distance separating plate (2), the up-down moving device (3) is arranged on one side of the distance separating plate (2) far away from the bottom plate (1), a transverse sliding rail (15) is horizontally arranged in the middle of the bottom plate (1), and the transverse sliding rail, the outer side of the transverse sliding rail (15) is connected with a second sliding block (16) in a sliding mode, the second sliding block (16) is fixedly connected with the magnetic rod assembly (5), the top of the bottom plate (1) is provided with a lifting device (4), the magnetic rod assembly (5) is arranged at the bottom of the lifting device (4), and the lifting device (4) is in transmission connection with the magnetic rod assembly (5).
2. The nucleic acid extractor separation device according to claim 1, wherein: the first sliding block (14) is at least provided with one linear guide rail (13) on each side, the back of the first sliding block is fixedly connected with the two ends of the distance-dividing plate (2) respectively, at least one transverse sliding rail (15) is arranged, the second sliding blocks (16) are uniformly arranged on each transverse sliding rail (15), and the back of each transverse sliding block is fixedly connected with the magnetic rod assembly (5).
3. The nucleic acid extractor separation device according to claim 1, wherein: at least two guide holes (21) are arranged, and the hole center distances between two adjacent guide holes (21) on the same horizontal plane are the same.
4. The nucleic acid extractor separation device according to claim 1, wherein: the up-down moving device (3) comprises a first motor fixing plate (31), a first synchronizing wheel (33), a screw rod supporting seat (34) and a second synchronizing wheel (37), the first motor fixing plate (31) is installed on one side, far away from the distance separating plate (2), of the bottom plate (1), a stepping motor (32) is installed at the bottom of the first motor fixing plate (31), an output shaft of the stepping motor (32) penetrates through the top of the first motor fixing plate (31) and is fixedly connected with the first synchronizing wheel (33), the screw rod supporting seat (34) is fixed at the upper end and the lower end of the screw rod fixing plate (11) on one side of the first motor fixing plate, a ball screw rod (35) is arranged inside the screw rod supporting seat (34), a screw rod nut seat (36) is arranged in the middle of the ball screw rod (35), and the screw rod nut seat (36) is connected with one end side face of the distance separating, the top of the ball screw (35) penetrates through the top of the screw support seat (34) and is fixedly connected with a second synchronous wheel (37), and the second synchronous wheel (37) is in transmission connection with the first synchronous wheel (33) through a synchronous belt (38).
5. The nucleic acid extractor separation device according to claim 1, wherein: elevating gear (4) include second motor fixed plate (41), top fixed connection in the middle of one end and bottom plate (1) of second motor fixed plate (41), second photoelectric switch (42) are installed to one side of second motor fixed plate (41), lead screw motor (43) are installed at the top of second motor fixed plate (41), the output shaft of lead screw motor (43) passes through ring flange (44) and is connected with bar magnet subassembly (5) transmission.
6. The nucleic acid extractor separation device according to claim 1, wherein: bar magnet subassembly (5) are provided with two sets ofly at least, bar magnet subassembly (5) are including bar magnet (51), bearing frame (52), rotate and are tied (57) and linking bridge (59), spout (58) have been seted up to the inside of bearing frame (52), it sets up inside spout (58) to rotate to tie (57), linking bridge (59) are through rotating tie (57) and spout (58) and bearing frame (52) swing joint, bar magnet (51) set up the bottom at linking bridge (59), linking bridge (59) and the swing joint of bar magnet (51).
7. The nucleic acid extractor separation device according to claim 6, wherein: the connecting bracket (59) comprises a first slider connecting rod (53), a second slider connecting rod (54) and a third slider connecting rod (55), the first slider connecting rod (53) is positioned right above the second slider connecting rod (54), one side of the first slider connecting rod (53) is fixedly connected with one side of the second slider connecting rod (54), the connecting end of the first slider connecting rod is fixedly connected with the third slider connecting rod (55), one side of the third slider connecting rod (55) is fixedly connected with the second slider (16), the other side of the third slider connecting rod (55) is in rolling connection with the distance-dividing plate (2) through a roller arranged in the guide hole (21), a magnetic rod fixing shaft (56) is arranged between the other sides of the first slider connecting rod (53) and the second slider connecting rod (54), the top of the magnetic rod fixing shaft (56) penetrates through the first slider connecting rod (53) and is fixedly connected with the shaft center of the rotating bolt (57), the bottom of the magnetic rod fixing shaft (56) penetrates through the second sliding block connecting rod (54) to be movably connected with the magnetic rod (51).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920425953.0U CN210163436U (en) | 2019-03-29 | 2019-03-29 | Nucleic acid draws appearance with dividing apart from device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920425953.0U CN210163436U (en) | 2019-03-29 | 2019-03-29 | Nucleic acid draws appearance with dividing apart from device |
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| Publication Number | Publication Date |
|---|---|
| CN210163436U true CN210163436U (en) | 2020-03-20 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201920425953.0U Active CN210163436U (en) | 2019-03-29 | 2019-03-29 | Nucleic acid draws appearance with dividing apart from device |
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| Country | Link |
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| CN (1) | CN210163436U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113694983A (en) * | 2021-08-06 | 2021-11-26 | 北京擎科生物科技有限公司 | Variable-pitch liquid transfer device and gun head variable-pitch part |
-
2019
- 2019-03-29 CN CN201920425953.0U patent/CN210163436U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113694983A (en) * | 2021-08-06 | 2021-11-26 | 北京擎科生物科技有限公司 | Variable-pitch liquid transfer device and gun head variable-pitch part |
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Effective date of registration: 20211101 Address after: 215522 No. 8, Shengyu Avenue, Haiyu Town, Changshu City, Suzhou City, Jiangsu Province Patentee after: SUZHOU ENRICHING BIOTECHNOLOGY CO.,LTD. Address before: 211100 No.18 Zhilan Road, gaoxinyuan, Jiangning District, Nanjing City, Jiangsu Province Patentee before: NANJING ENRICHING MAIGE BIOCHEMISTRY APPARATUS CO.,LTD. |