CN210134093U - Freeze-drying equipment that bdellovibrio used - Google Patents
Freeze-drying equipment that bdellovibrio used Download PDFInfo
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- CN210134093U CN210134093U CN201920259858.8U CN201920259858U CN210134093U CN 210134093 U CN210134093 U CN 210134093U CN 201920259858 U CN201920259858 U CN 201920259858U CN 210134093 U CN210134093 U CN 210134093U
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Abstract
The utility model discloses a freeze-drying equipment that bdellovibrio used belongs to drying equipment. The method comprises the following steps: the device comprises an equipment box and a material box. The equipment box includes: the first box body is provided with a control electric cabinet, a temperature control device and an air compressor in the first box body; the material case includes: the second box sets up on the second box, and with a plurality of shelves that temperature regulating equipment's cooling tube and heater are connected set up second bottom of the case portion and with air compressor's air inlet, set up and be in water trapper on the air inlet. The cooling circulation pipeline is arranged in each layer of shelf, so that the distance between the cooling pipeline and the bdellovibrio is reduced, and the temperature distribution is more uniform; the air inlet of the air compressor is provided with the water catcher, so that the water vapor content in the second box body is reduced, and the freeze-drying efficiency is improved. The temperature uniformity of the existing bdellovibrio bacteriovorus freeze-drying equipment is improved, and the survival rate of the freeze-dried bacterial colony is increased.
Description
Technical Field
The utility model belongs to drying equipment, in particular to freeze-drying equipment for bdellovibrio bacteriovorus.
Background
Bdellovibrio bacteriovorus is a kind of parasitic bacteria mainly preying on pathogenic bacteria such as escherichia coli, salmonella, vibrio parahaemolyticus and the like. Researches indicate that the bdellovibrio has remarkable effects on purifying the water quality of the culture water body and controlling or reducing the occurrence and prevalence of aquatic animal diseases, and the bdellovibrio is added in the culture process to achieve the effects of preventing and treating diseases, improving the survival rate, increasing the body weight and the body length and purifying the culture ecological environment. Bdellovibrio bacteriovorus is an effective biological preparation for preventing and treating diseases, and is deeply favored by people in the industries of preventing and treating animal diseases and improving environment.
In the prior application, the quality guarantee period of the liquid bdellovibrio bacteriovorus preparation at normal temperature is only about three or four months, which seriously influences the popularization and application of the biological product, especially in the field of production and culture.
However, most of the existing bdellovibrio bacteriovorus freeze-drying equipment adopts food-grade freeze-drying equipment as a basis to carry out freeze-drying, but the freeze-drying machine for food has no high requirement on temperature uniformity when freeze-drying food; since bdellovibrio bacteriovorus needs to be lyophilized uniformly to a constant value, the temperature uniformity directly affects the survival rate of freeze-dried colonies.
SUMMERY OF THE UTILITY MODEL
Utility model purpose: provides a freeze-drying device for bdellovibrio bacteriovorus, which is used for improving the temperature uniformity of the existing freeze-drying device for bdellovibrio bacteriovorus and improving the survival rate of bacterial colonies after freeze-drying.
The technical scheme is as follows: a freeze-drying equipment for bdellovibrio comprises: the device comprises an equipment box and a material box.
An equipment cabinet comprising: the air conditioner comprises a first box body, a control electric cabinet, a temperature control device, an air compressor, a plurality of radiating fans and a radiating plate, wherein the control electric cabinet is arranged in the first box body and connected with a power line;
a material tank comprising: the second box sets up on the second box, and with a plurality of shelves that temperature regulating equipment's cooling tube and heater are connected set up second bottom of the case portion and the air inlet that is connected with air compressor set up water trapper on the air inlet, and set up and be in a door frame in the positive place ahead of box.
In a further embodiment, the second tank is made of stainless steel and has a wall thickness greater than 10 mm.
In a further embodiment, the water catcher is a spiral channel, a cooling circulation pipeline is arranged in the pipe wall of the spiral channel, and a water-absorbing chemical substance is placed at the bottom of the spiral channel.
In a further embodiment, the shelf comprises; the device comprises a fixing plate, flow controllers arranged on two sides of the fixing plate, and a plurality of groups of cooling circulating pipes and heating circulating pipes which are arranged in the fixing plate and connected with temperature control equipment through the flow controllers.
In a further embodiment, the joints of the door frame and the second box body are provided with sealing gaskets, and the door frame is provided with an observation window.
In a further embodiment, the control electric cabinet is provided with a microprocessor and a wireless transmission module, and is connected with the terminal equipment.
In a further embodiment, the second box is provided with a plurality of temperature sensing devices and is connected with the microprocessor.
Has the advantages that: the utility model relates to a freeze-drying device for bdellovibrio, which arranges a cooling circulation pipeline in each layer of shelf to reduce the distance between the cooling pipeline and the bdellovibrio and make the temperature distribution more uniform; a plurality of temperature sensors are arranged on the second box body and used for monitoring the temperature difference in the material box, adjusting the cooling power on the shelf and improving the uniformity of the temperature in the box; the air inlet of the air compressor is provided with the water catcher, so that the water vapor content in the second box body is reduced, and the freeze-drying efficiency is improved. The temperature uniformity of the existing freeze-drying equipment for bdellovibrio is improved, and the survival rate of the freeze-dried bacterial colony is improved.
Drawings
Fig. 1 is a schematic structural diagram of the present invention.
Fig. 2 is a schematic structural view of the shelf of the present invention.
Fig. 3 is a schematic structural diagram of the door frame of the present invention.
Fig. 4 is a schematic structural view of the water trap of the present invention.
The reference signs are: the device comprises a first box body 1, a control electric cabinet 2, a temperature control device 3, an air compressor 4, a cooling fan 5, a second box body 6, a temperature sensing device 7, a shelf 8, an air inlet 9, a water catcher 10, a door frame 11, a radiator 301, a fixing plate 801, a flow controller 802, a cooling circulating pipe 803, a heating circulating pipe 804, a spiral channel 1001, a cooling pipe 1002, an observation window 1101 and a door handle 1102.
Detailed Description
In the following description, numerous specific details are set forth in order to provide a more thorough understanding of the present invention. It will be apparent, however, to one skilled in the art, that the present invention may be practiced without one or more of these specific details. In other instances, well-known features have not been described in order to avoid obscuring the present invention.
In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and simplification of description, but do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus, should not be construed as limiting the present invention. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.
As shown in the attached figure 1, the freeze-drying equipment for bdellovibrio comprises: two parts of equipment box and material box
The equipment box includes: the air conditioner comprises a first box body 1, a control electric cabinet 2, a temperature control device 3, an air compressor 4, a cooling fan 5 and a cooling plate (not shown in the schematic diagram). Control electrical cabinet 2 sets up in the first box 1 be connected with the power cord, temperature regulating device 3 and air compressor 4 through the electric wire with control electrical cabinet 2 is connected, has a plurality of radiator fan 5 to set up on the first box 1 of radiator 301 one side that is close to temperature regulating device 3, and the heating panel setting is in the opposite side of box. Basic equipment arranged in the equipment box provides freeze drying conditions, and specifically, the temperature control equipment 3 adopts a direct cooling and heating type cooling system, can cool to about-60 ℃ and heat to about 70 ℃; the air compressor 4 can provide a vacuum environment.
The material case includes: a second box 6, a temperature sensing device 7, a shelf 8, an air inlet 9, a water catcher 10 and a door frame 11. The second box 6 is a closed pressure vessel, and is made of stainless steel material, and the wall thickness is larger than 10 mm. A plurality of shelves 8 are arranged on the second box 6, as shown in fig. 2, and the shelves 8 comprise; a fixing plate 801, a flow controller 802, a cooling circulation pipe 803 and a heating circulation pipe 804; the flow controllers 802 are arranged on two sides of the fixing plate 801, a plurality of groups of cooling circulating pipes 803 and heating circulating pipes 804 are arranged in the fixing plate 801, and the flow controllers 802 are connected with the cooling pipes and the heaters of the temperature control equipment 3. The cooling circulation pipe 803 is arranged in each layer of shelf 8, so that the distance between the cooling pipe 1002 and the bdellovibrio is reduced, cold air directly acts on the bdellovibrio, the change rate of the regional temperature is small, and the temperature distribution is more uniform. An air inlet 9 connected with the air compressor 4 is arranged at the bottom of the second box 6, and a water catcher 10 is arranged on the air inlet 9, wherein, as shown in fig. 4, the water catcher 10 is a spiral channel 1001, a cooling circulation pipe 803 is arranged around the spiral channel 1001, and a water-absorbing chemical substance is arranged at the bottom of the spiral channel 1001; the water vapor in the second box 6 can be condensed and collected through the spiral channel 1001, and meanwhile, the water vapor in the box is further absorbed through the water-absorbing chemical substances, so that the water vapor content is reduced. A door frame 11 is arranged right in front of the box body. Specifically, the door frame 11 all is provided with sealed the pad with the junction of second box 6 to guarantee the leakproofness in the second box 6, as shown in fig. 3 be provided with observation window 1101 and handle on the door frame 11, under guaranteeing user's safety, be convenient for observe the behavior in the second box 6.
As a preferred scheme, a microprocessor and a wireless transmission module are arranged on the control electric cabinet 2 and connected with the terminal equipment. This can be used to control the lyophilization apparatus via the terminal device. Meanwhile, the second box 6 is provided with a plurality of temperature sensing devices 7 and connected with the microprocessor, when one of the temperature sensors detects that the temperature deviation of a certain area is larger than the temperature difference of the standard temperature, the flow of the cooling liquid in the cooling circulation pipe 803 close to the area can be adjusted through the microprocessor center, the temperature of the cooling liquid is corrected, and the temperature uniformity in the second box 6 is ensured.
In order to facilitate the understanding of the technical scheme of the freeze-drying equipment for bdellovibrio bacteriovorus, the processing technology is briefly explained.
S1, preprocessing: cooling the bdellovibrio bacteriovorus liquid to 4-7 ℃, cooling for 30min, then adjusting the temperature of the clapboard to-20 to-50 ℃, and freezing the bdellovibrio bacteriovorus liquid for 1-4 h.
S2, freeze drying: air in the second box body 6 is extracted through the air compressor 4, the vacuum degree is reduced to 2.0-20 pa, the temperature in the second box body 6 is kept at-20 ℃ to-50 ℃, and the duration time is 5-24 hours.
S3, analysis and drying: and continuously keeping the vacuum degree, adjusting the temperature of the partition plate to be 20-50 ℃, and rapidly heating the interior of the second box body 6 to 10-25 ℃.
S4, post-processing: stopping the machine, taking out the fluffy bdellovibrio powder, sieving, packaging and sealing.
It should be noted that the various features described in the above embodiments may be combined in any suitable manner without departing from the scope of the invention. In order to avoid unnecessary repetition, the present invention does not separately describe various possible combinations.
Claims (7)
1. A freeze-drying equipment that bdellovibrio used which characterized in that includes:
an equipment cabinet comprising: the air conditioner comprises a first box body, a control electric cabinet, a temperature control device, an air compressor, a plurality of radiating fans and a radiating plate, wherein the control electric cabinet is arranged in the first box body and connected with a power line;
a material tank comprising: the second box sets up on the second box, and with a plurality of shelves that temperature regulating equipment's cooling tube and heater are connected set up second bottom of the case portion and the air inlet that is connected with air compressor set up water trapper on the air inlet, and set up and be in a door frame in the positive place ahead of box.
2. The freeze-drying apparatus for bdellovibrio according to claim 1, wherein the second box is made of stainless steel and has a wall thickness greater than 10 mm.
3. The freeze-drying equipment for bdellovibrio according to claim 1, wherein the water catcher is a spiral channel, a cooling circulation pipeline is arranged in the pipe wall of the spiral channel, and a water-absorbing chemical substance is placed at the bottom of the spiral channel.
4. The lyophilization apparatus for bdellovibrio according to claim 3, wherein the shelf comprises: the device comprises a fixing plate, flow controllers arranged on two sides of the fixing plate, and a plurality of groups of cooling circulating pipes and heating circulating pipes which are arranged in the fixing plate and connected with temperature control equipment through the flow controllers.
5. The freeze-drying equipment for bdellovibrio according to claim 1, wherein the joints of the door frame and the second box are provided with sealing gaskets, and the door frame is provided with an observation window.
6. The freeze-drying device for bdellovibrio according to claim 1, wherein the control cabinet is provided with a microprocessor and a wireless transmission module and is connected with a terminal device.
7. The freeze-drying equipment for bdellovibrio according to claim 1, wherein the second box is provided with a plurality of temperature sensing devices and is connected with a microprocessor.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920259858.8U CN210134093U (en) | 2019-03-01 | 2019-03-01 | Freeze-drying equipment that bdellovibrio used |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920259858.8U CN210134093U (en) | 2019-03-01 | 2019-03-01 | Freeze-drying equipment that bdellovibrio used |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN210134093U true CN210134093U (en) | 2020-03-10 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201920259858.8U Active CN210134093U (en) | 2019-03-01 | 2019-03-01 | Freeze-drying equipment that bdellovibrio used |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN210134093U (en) |
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2019
- 2019-03-01 CN CN201920259858.8U patent/CN210134093U/en active Active
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