CN210071846U - Solid phase agglutination serology experiment microplate with movable indication lath - Google Patents

Abstract

The utility model discloses a solid phase agglutination serology experiment microplate with movable instruction lath, including square frame type support and reagent lath, the both ends of reagent lath support on square frame type support and with square frame type support releasable connection, the last distribution of reagent lath has a plurality of miniature reagent pipes, still includes movable instruction lath, movable instruction lath is pegged graft on square frame type support, and is used for right the experiment project content of reagent lath instruct. The movable indicating lath comprises a cross matching experiment indicating lath, an irregular antibody screening experiment indicating lath and a neonatal hemolytic disease detection experiment indicating lath. Due to the fact that the movable indicating lath is additionally arranged, the experiment content can be clearly indicated, interpretation errors are avoided, and particularly, the cross matching experiment, the irregular antibody screening experiment and the neonatal hemolytic disease detection experiment can be distinguished.

Description

Solid phase agglutination serology experiment microplate with movable indication lath

Technical Field

The utility model relates to a solid phase agglutination serology experimental facility, in particular to a solid phase agglutination serology experimental microplate.

Background

The solid phase agglutination method is a detection method with high sensitivity and high detection flux, and can be used for serological experiments such as cross matching, irregular antibody screening, neonatal hemolytic disease detection and the like. Because the adopted microplate is 96-hole, the experimental result can be automatically read by a machine during interpretation, and can also be manually interpreted. Since the 96-well microplate is 8 wells per plate from top to bottom, there are 12 microplates from left to right, without any special label. When manual interpretation is performed, if there is no interpretation indicating device for the experimental result, interpretation is relatively inconvenient and interpretation errors are easily caused.

SUMMERY OF THE UTILITY MODEL

In order to overcome the defects, the utility model aims to provide a solid phase agglutination serology experiment microplate with a movable indication lath, which can clearly indicate the experiment contents and avoid interpretation errors.

In order to solve the technical problem, the utility model discloses the technical scheme who adopts is:

the utility model provides a solid phase agglutination serology experiment microplate with movable instruction lath, includes square frame type support and reagent lath, the both ends of reagent lath support on square frame type support and with square frame type support releasable connection, the reagent lath is last to distribute and is had a plurality of miniature reagent pipes, still includes movable instruction lath, movable instruction lath pegs graft on square frame type support for to the experiment project content of reagent lath instruct.

Further, interval distribution has a plurality of positioning slot on the side A top surface of square frame type support, and interval distribution has a plurality of stoppers on the side B top surface of square frame type support, be equipped with the location inserted sheet on the lower surface of movable instruction lath one end, the other end is equipped with the breach, and movable instruction lath's both ends support on the side A and the side B of square frame type to make the location inserted sheet insert the positioning slot, the stopper is located breach department.

Further, the movable indicating lath is a cross matching experiment indicating lath, the surface of the cross matching experiment indicating lath is marked with a plurality of main side cross matching blood marks and a plurality of secondary side cross matching blood marks, the plurality of main side cross matching blood marks and the plurality of secondary side cross matching blood marks are distributed in a staggered manner, and the main side cross matching blood marks and the secondary side cross matching blood marks respectively correspond to the experiment item contents of the micro reagent tubes on the reagent lath.

Furthermore, the movable indication lath comprises an irregular antibody screening experiment indication lath, wherein the surface of the irregular antibody screening experiment indication lath is sequentially marked with three screening cell marks and one positive control mark, and the three screening cell marks and the one positive control mark correspond to the experiment project content of the miniature reagent tube on the reagent lath.

Furthermore, the movable indication lath is an indication lath for a neonatal hemolytic disease detection experiment, the surface of the indication lath for the neonatal hemolytic disease detection experiment is sequentially marked with cell identifiers of three blood types, namely, a type A, a type B and a type O and a positive control identifier, and the cell identifiers of the three blood types, namely, the type A, the type B and the type O and the positive control identifier respectively correspond to the experiment project contents of the miniature reagent tubes on the reagent lath.

Furthermore, the reagent plate strip comprises a plane support plate A, a plane support plate B and a plurality of miniature reagent tubes, the miniature reagent tubes are arranged in a row, adjacent miniature reagent tubes are connected through a connecting sheet, and one end of the plane support plate A and one end of the plane support plate B are respectively connected with the miniature reagent tubes on the two sides; be equipped with the location inserted sheet on plane backup pad A's the lower surface, be equipped with the breach on the plane backup pad B, when the reagent lath passes through plane backup pad A, plane backup pad B and supports respectively on side A, the side B of square frame type support, during the location inserted sheet inserted the location slot, the stopper was located breach department.

Furthermore, 8 micro reagent tubes are arranged on the reagent plate strip.

The beneficial effects of the utility model reside in that:

due to the fact that the movable indicating lath is additionally arranged, the experiment content can be clearly indicated, interpretation errors are avoided, and particularly, the cross matching experiment, the irregular antibody screening experiment and the neonatal hemolytic disease detection experiment can be distinguished.

Drawings

The invention will be further explained with the aid of the accompanying drawings, in which, however, the embodiments in the drawings do not constitute any limitation to the invention, and for a person skilled in the art, without inventive step, further drawings can be obtained in accordance with the following drawings:

fig. 1 is a schematic structural view of the present invention;

FIG. 2 is a top view of FIG. 1;

FIG. 3 is a side view of an indicator panel of the neonatal hemolytic detection assay shown in FIG. 1;

FIG. 4 is a schematic view of the structure of the reagent strip of FIG. 1.

In the figure: 1. a square frame type support; 2. a reagent strip; 3. cross matching experiment indicator panel; 4. irregular antibody screening test indicator panel; 5. an indicator strip for hemolytic disease detection experiments of newborn; 6. a micro reagent tube; 7. side edge A; 8. positioning the slot; 9. side B; 10. a limiting block; 11. positioning the inserting sheet; 12. a notch; 13. a planar support plate A; 14. a planar support plate B; 15. connecting sheets; 16. a plug-in sheet; 17. and positioning the notch.

Detailed Description

In order to make the technical solutions of the present invention better understood, the following detailed description of the present invention is provided with reference to the accompanying drawings and specific embodiments, and it should be noted that the embodiments and features of the embodiments of the present invention can be combined with each other without conflict.

As shown in figures 1 and 2, the solid phase agglutination serology experiment microplate with the movable indication lath comprises a square frame type bracket 1 and reagent laths 2, wherein two ends of each reagent lath 2 are supported on the square frame type bracket 1 and are detachably connected with the square frame type bracket, and 8 miniature reagent tubes 6 are distributed on each reagent lath 2. Also comprises a movable indicating panel, which comprises a cross matching experiment indicating panel 3, an irregular antibody screening experiment indicating panel 4 and a neonatal hemolytic disease detection experiment indicating panel 5. Specifically, all the movable indicating strips are inserted into the square frame type support to indicate the contents of the experiment items of the reagent strip 2.

The surface of the cross matching experiment indication lath 3 is marked with a plurality of main side cross matching blood marks and a plurality of secondary side cross matching blood marks, the main side cross matching blood marks and the secondary side cross matching blood marks are distributed in a staggered manner, specifically, the main side cross matching blood marks are represented by Chinese characters 'main', the secondary side cross matching blood marks are represented by Chinese characters 'main', and the main, secondary, main and secondary 8 marks are sequentially distributed on the surface of the cross matching experiment indication lath and respectively correspond to the experiment project contents of the 8 miniature reagent tubes on the reagent lath.

The surface of the irregular antibody screening experiment indication plate strip 4 is sequentially marked with three screening cell marks and one positive control mark, and the three screening cell marks and the one positive control mark correspond to the experiment project content of the miniature reagent tube on the reagent plate strip. Specifically, the irregular antibody screening experiment refers to the reaction of screening cells I, II and III with plasma to be detected, and finally the conclusion of whether the irregular antibody exists is obtained. When the solid phase agglutination method is adopted, 8 miniature reagent tubes 3 are distributed on the reagent strip 2, the No. I, II and III screening cells and the irregular antibody for positive control are sequentially added into the 1 st to 4 th miniature reagent tubes on the reagent strip 2, and the No. I, II and III screening cells and the irregular antibody for positive control are also sequentially added into the 5 th to 8 th miniature reagent tubes on the reagent strip 2. That is, 8 micro reagent tubes of 1 reagent strip can be used for 2-person antibody screening experiments. Thus, the designed irregular antibody screening experiment indicated that the panels were labeled with: ic, IIc, IIIc, +, ic, IIc, IIIc, +. The mark "ic" shows that the miniature reagent tube corresponding to the mark is added with the screening cell I, the mark "IIc" shows that the miniature reagent tube corresponding to the mark is added with the screening cell II, the mark "IIIc" shows that the miniature reagent tube corresponding to the mark is added with the screening cell III, and the mark "+" shows that the miniature reagent tube corresponding to the mark is added with the irregular antibody for positive control.

The surfaces of the neonatal hemolytic disease detection indication strip 5 are sequentially marked with cell identifiers of three blood types A, B and O and a positive control identifier, and the cell identifiers of the three blood types A, B and O and the positive control identifier respectively correspond to the experimental item contents of the miniature reagent tubes on the reagent strip. Specifically, antibody detection for neonatal leukemia includes plasma free antibody detection and a diffused antibody detection, both of which are performed using A, B, O cells, respectively. When the solid phase agglutination method is adopted, A, B, O cells and a positive control reagent are sequentially added into the 1 st to 4 th miniature reagent tubes on the reagent strip 2 for detecting free antibodies in blood plasma; a, B, O cells and a positive control reagent are sequentially added into the 5 th to 8 th miniature reagent tubes on the reagent strip 2 for detecting the antibody in the diffusion liquid. Thus, the designed neonatal hemolytic disease detection experiment indicated that the panels were marked with: ac. Bc, Oc, +, Ac, Bc, Oc, +. The first 4 markers represent cells reacting with free antibody in plasma and the positive control reagent, and the last 4 markers represent cells reacting with antibody in the bleed and the positive control reagent.

As shown in fig. 2 and 3, since the specific structures of the movable indicating slats of the present patent are the same, the indicating slat 5 for neonatal hemolytic disease detection test is described as follows: there are a plurality of positioning slot 8 on the side A7 top surface of square frame type support 1 at interval distribution, and there are a plurality of stopper 10 on the side B9 top surface of square frame type support 1 at interval distribution, be equipped with location inserted sheet 11 on the lower surface of movable indication lath one end, the other end is equipped with breach 12, and the both ends of movable indication lath are supported on the side A7 and the side B9 of square frame type to make location inserted sheet 11 insert positioning slot 8 in, stopper 10 is located breach 12 department.

As shown in fig. 4, the reagent plate strip 2 includes a planar support plate a13, a planar support plate B14 and a plurality of micro reagent tubes 6, the micro reagent tubes 6 are arranged in a row, adjacent micro reagent tubes 6 are connected by a connecting piece 15, one end of the planar support plate a13 and one end of the planar support plate B14 are respectively connected with the micro reagent tubes 6 on both sides, the lower surface of the planar support plate a is provided with a plug piece 16, the planar support plate B14 is provided with a positioning notch 17, when the reagent plate strip 2 is respectively supported on the side a7 and the side B9 of the square frame bracket by the planar support plate a13 and the planar support plate B14, the plug piece 16 is inserted into the positioning slot 8, and the limiting block 10 is located at the positioning notch 17.

The characteristics of this patent: the movable indication strip is designed according to different solid-phase agglutination serology experiments, and can be suitable for indicating the results of various different solid-phase agglutination serology experiments; each label indicating different meanings on the bar is designed to be different in color, such as colors of red, green and blue for Ac, Bc and Oc. All marks correspond to the miniature reagent tubes on the reagent strip one to one, and therefore the result interpretation directivity error is avoided.

The above description is a preferred embodiment of the present invention, and certainly not intended to limit the scope of the present invention, it should be pointed out that, for a person skilled in the art, modifications or equivalent substitutions may be made to the technical solution of the present invention without departing from the scope of the present invention.

Claims (7)

1. The utility model provides a solid phase agglutination serology experiment microplate with movable instruction lath, includes square frame type support and reagent lath, the both ends of reagent lath support on square frame type support and with square frame type support releasable connection, it has a plurality of miniature reagent pipes, its characterized in that to distribute on the reagent lath: the movable indication batten is inserted into the square frame type support and used for indicating the experiment item content of the reagent batten.

2. The solid phase agglutination serological experimental microplate with a movable indicator strip according to claim 1 wherein: the utility model discloses a square frame type indicator strip, including but not limited to, movable indicator strip, side A and side B, the interval distribution has a plurality of positioning slot on the side A top surface of square frame type support, and the interval distribution has a plurality of stoppers on the side B top surface of square frame type support, be equipped with the location inserted sheet on the lower surface of movable indicator strip one end, the other end is equipped with the breach, and the both ends of movable indicator strip support on the side A and the side B of square frame type to make the location inserted sheet insert positioning slot, the stopper is located breach department.

3. The solid-phase agglutination serological experiment microplate with movable indicator strips according to claim 1 or 2, wherein: the movable indicating lath is a cross blood matching experiment indicating lath, the surface of the cross blood matching experiment indicating lath is marked with a plurality of main side cross blood matching marks and a plurality of secondary side cross blood matching marks, the plurality of main side cross blood matching marks and the plurality of secondary side cross blood matching marks are distributed in a staggered mode, and the main side cross blood matching marks and the secondary side cross blood matching marks respectively correspond to the experiment project contents of the micro reagent tubes on the reagent lath.

4. The solid-phase agglutination serological experiment microplate with movable indicator strips according to claim 1 or 2, wherein: the movable indication lath comprises an irregular antibody screening experiment indication lath, wherein the surface of the irregular antibody screening experiment indication lath is sequentially marked with three screening cell marks and one positive control mark, and the three screening cell marks and the one positive control mark correspond to the experiment project content of the miniature reagent tube on the reagent lath.

5. The solid-phase agglutination serological experiment microplate with movable indicator strips according to claim 1 or 2, wherein: the movable indication lath is used for indicating a neonatal hemolytic disease detection experiment, cell identifiers of which three blood types are A type, B type and O type and a positive control identifier are sequentially marked on the surface of the neonatal hemolytic disease detection experiment indication lath, and the cell identifiers of which the three blood types are A type, B type and O type and the positive control identifier respectively correspond to the experiment project contents of the miniature reagent tube on the reagent lath.

6. The solid phase agglutination serological experimental microplate with a movable indicator strip according to claim 1 wherein: the reagent plate strip comprises a plane supporting plate A, a plane supporting plate B and a plurality of miniature reagent tubes, the miniature reagent tubes are arranged in a row, adjacent miniature reagent tubes are connected through a connecting sheet, and one end of the plane supporting plate A and one end of the plane supporting plate B are respectively connected with the miniature reagent tubes on the two sides; be equipped with the location inserted sheet on plane backup pad A's the lower surface, be equipped with the breach on the plane backup pad B, when the reagent lath passes through plane backup pad A, plane backup pad B and supports respectively on side A, the side B of square frame type support, during the location inserted sheet inserted the location slot, the stopper was located breach department.

7. The solid phase agglutination serological experimental microplate with a movable indicator strip according to claim 1 wherein: the reagent batten is provided with 8 miniature reagent tubes.

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