CN209988343U - Cell storage bag with recognition function - Google Patents
Cell storage bag with recognition function Download PDFInfo
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- CN209988343U CN209988343U CN201920082670.0U CN201920082670U CN209988343U CN 209988343 U CN209988343 U CN 209988343U CN 201920082670 U CN201920082670 U CN 201920082670U CN 209988343 U CN209988343 U CN 209988343U
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- Prior art keywords
- bag
- bag body
- piston
- inner bag
- cell storage
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- 238000003860 storage Methods 0.000 title claims abstract description 28
- 239000007788 liquid Substances 0.000 claims abstract description 24
- 210000004027 cell Anatomy 0.000 claims abstract description 23
- 210000000130 stem cell Anatomy 0.000 claims abstract description 22
- 239000002826 coolant Substances 0.000 claims 1
- 238000009434 installation Methods 0.000 claims 1
- 238000004321 preservation Methods 0.000 abstract description 9
- 238000000034 method Methods 0.000 abstract description 7
- 239000000110 cooling liquid Substances 0.000 abstract description 6
- 239000011229 interlayer Substances 0.000 abstract description 4
- 238000001816 cooling Methods 0.000 abstract description 3
- 230000000694 effects Effects 0.000 abstract description 3
- 238000002659 cell therapy Methods 0.000 description 3
- 238000011084 recovery Methods 0.000 description 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- 238000007599 discharging Methods 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 238000007710 freezing Methods 0.000 description 2
- 230000008014 freezing Effects 0.000 description 2
- 238000003780 insertion Methods 0.000 description 2
- 230000037431 insertion Effects 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 239000012472 biological sample Substances 0.000 description 1
- 238000005138 cryopreservation Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 210000004700 fetal blood Anatomy 0.000 description 1
- 238000003306 harvesting Methods 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 238000012606 in vitro cell culture Methods 0.000 description 1
- 239000010410 layer Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 238000000275 quality assurance Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
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Abstract
The utility model discloses a cell storage bag with recognition function, which comprises a bag body and a quantitative conveyor arranged with the bag body through a connecting structure, wherein the bag body consists of an outer bag and an inner bag which are integrally formed, an interlayer filled with cooling liquid is arranged between the outer bag and the inner bag, the top of the outer bag is provided with a hanging ring which is convenient for hanging the whole device, and the bottom in the inner bag is provided with an inner air bag; the device can accurately remove redundant air in the inner bag in the preservation process by arranging the inner air bag in the inner bag, so that the whole volume of the bag body is reduced, the preservation is convenient, the stem cell liquid is fully attached to the inner wall of the inner bag, the heat exchange with cooling liquid can be rapidly carried out, the cooling efficiency in the preservation process is improved, and the preservation effect is ensured; through the setting of ration conveyer, can the accurate storage volume of mastering a single storage bag, the function of quick discernment can be played when a plurality of storage bags are concentrated to deposit in the setting of label column.
Description
Technical Field
The utility model relates to a stem cell preservation technique specifically is a cell storage bag with recognition function.
Background
The stem cells are usually stored in a low-temperature refrigerator/liquid nitrogen tank at-85 ℃ or-196 ℃ according to the required storage life; for stem cells with a short period of time after collection (< 6 months) they are usually frozen at-85 ℃ in a deep cryorefrigerator.
With the development of biological technologies, cell therapy is rapidly developing and increasingly accepted worldwide. The basis of cell therapy is the harvesting and storage of viable cells. In addition, in vitro culture of cells has also been widely used in various fields of biological research. In the in vitro cell culture work, in order to preserve cells and enable the cells to have biological activity for a long time, the freezing and recovery of the cells become a crucial link. The preparation and storage of cells, especially the low-temperature storage and recovery conditions of biological samples such as umbilical cord blood, stem cells and the like and the prevention of pollution of operation processes are important subjects of the current clinical application of cell therapy. Various cell banks are established in many countries and regions, and optimizing cell cryopreservation recovery procedures and preventing pollution have become the prerequisites for cell production and cell quality assurance.
At present to freezing of this kind of stem cell, there is not unified operating specification, the storage bag that each unit chose for use is also different, and the most major structure of current storage bag is comparatively simple, and its structure is mostly the double-deck bag that has the filling refrigerating fluid intermediate layer, nevertheless to the cell liquid of bag after, has unnecessary air in the bag easily, not only causes cell and refrigerating fluid can not fully realize the heat transfer contact, and other biological influences that probably carry in the air in addition store the effect.
Disclosure of Invention
An object of the utility model is to provide a cell storage bag with recognition function to solve the problem of proposing among the above-mentioned background art.
In order to achieve the above object, the utility model provides a following technical scheme:
a cell storage bag with an identification function comprises a bag body and a quantitative conveyor which is installed with the bag body through a connecting structure, wherein the bag body consists of an outer bag and an inner bag which are integrally formed, an interlayer filled with cooling liquid is arranged between the outer bag and the inner bag, the top of the outer bag is provided with a hanging ring which is convenient for hanging the whole device, the inner bottom of the inner bag is provided with an inner air bag, the inner air bag is hollow and is communicated with an air charging and discharging port positioned below the bag body through a connecting pipe inserted in the center of the bottom of the bag body; the outer wall of the bag body is also provided with a label bar; the connecting structure comprises a conveying pipe positioned at the top of the bag body and a threaded sleeve positioned at the bottom of the quantitative conveyor, the lower end of the conveying pipe is communicated with the inside of the inner bag, a connecting threaded pipe is arranged at the top of the conveying pipe, and the connecting threaded pipe is in threaded connection with the threaded sleeve.
The quantitative conveyor is used for quantitatively conveying stem cells to the bag body, the quantitative conveyor main body is a square shell with a buffer cavity inside, a transparent window with scale marks is arranged on the outer wall of the shell, the top of the buffer cavity is connected with a piston cavity, a piston in sliding connection with the piston cavity is arranged in the piston cavity, a piston rod in an integrated structure with the piston top is installed in the center of the piston top, the upper end of the piston rod extends out of the upper portion of the shell, connectors are arranged on two sides of the shell respectively, a liquid inlet pipe communicated with the buffer cavity is arranged inside the connectors, the middle of the liquid inlet pipe is an expansion section, two sides of the expansion section are of an arc-shaped structure, a control valve is arranged in the expansion section, and a knob which extends out of the.
As the preferred scheme of the utility model: the inner side of the threaded sleeve is provided with an insertion pipe communicated with the buffer cavity, and a one-way valve is arranged in the insertion pipe.
Compared with the prior art, the beneficial effects of the utility model are that: the device can accurately remove redundant air in the inner bag in the preservation process by arranging the inner air bag in the inner bag, so that the whole volume of the bag body is reduced, the preservation is convenient, the stem cell liquid is fully attached to the inner wall of the inner bag, the heat exchange with cooling liquid can be rapidly carried out, the cooling efficiency in the preservation process is improved, and the preservation effect is ensured; through the setting of ration conveyer, can the accurate storage volume of mastering a single storage bag, the function of quick discernment can be played when a plurality of storage bags are concentrated to deposit in the setting of label column.
Drawings
Fig. 1 is a schematic structural diagram of the present invention.
Fig. 2 is a schematic structural view of the middle bag body of the present invention.
Fig. 3 is a cross-sectional view of the quantitative conveyor of the present invention.
In the figure, 1-bag body, 11-outer bag, 12-inner bag, 13-interlayer, 14-hanging ring, 15-conveying pipe, 16-connecting threaded pipe, 17-label column, 2-inner bag, 21-air charging and discharging port, 22-connecting pipe, 3-quantitative conveyor, 31-transparent window, 32-scale line, 33-buffer cavity, 34-inserting pipe, 35-threaded sleeve, 36-connector, 361-liquid inlet pipe, 362-expanding section, 363-control valve, 364-knob, 37-piston cavity, 4-piston rod and 41-piston.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and simplification of description, but do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus, should not be construed as limiting the present invention. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.
In the description of the present invention, it is to be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "connected," and "connected" are to be construed broadly, and may be, for example, fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood in specific cases to those skilled in the art.
Example 1:
referring to fig. 1-3, a cell storage bag with identification function comprises a bag body 1 and a quantitative conveyor 3 mounted on the bag body 1 through a connection structure, wherein the bag body 1 is composed of an outer bag 11 and an inner bag 12 which are integrally formed, an interlayer 13 filled with a cooling liquid is arranged between the outer bag 11 and the inner bag 12, a hanging ring 14 for hanging the whole device is arranged at the top of the outer bag 11, an inner bag 2 is arranged at the bottom of the inner bag 12, the inner bag 2 is hollow and is communicated with an air inflation and deflation port 21 positioned below the bag body 1 through a connecting pipe 22 inserted in the center of the bottom of the bag body 1, when the storage work of stem cells is carried out, after the delivery of a stem cell liquid into the inner bag 12 is finished, the inner bag 2 is inflated through the air inflation and deflation port 21 to expand the inner bag 2, so that redundant air in the inner bag 12 can be exhausted, after the exhaustion is finished, the bag body 1 is sealed and then the air in the inner bag 2 is exhausted, the whole volume of the bag body 1 is reduced, the bag body is convenient to store, stem cell liquid is fully attached to the inner wall of the inner bag 12, heat exchange can be rapidly carried out between the stem cell liquid and cooling liquid, and the cooling efficiency during storage is improved.
Specifically, the connecting structure comprises a conveying pipe 15 positioned at the top of the bag body 1 and a threaded sleeve 35 positioned at the bottom of the quantitative conveyor 3, the lower end of the conveying pipe 15 is communicated with the inside of the inner bag 12, a connecting threaded pipe 16 is arranged at the top of the conveying pipe 15, and the connecting threaded pipe 16 is in threaded connection with the threaded sleeve 35.
The quantitative conveyor 3 is used for quantitatively conveying stem cells into the bag body 1, the main body of the quantitative conveyor 3 is a square shell with a buffer cavity 33 inside, a transparent window 31 with scale marks 32 is arranged on the outer wall of the shell, the amount of the conveyed stem cell liquid can be accurately measured through the scale marks 32, the top of the buffer cavity 33 is connected with a piston cavity 37, a piston 41 in sliding connection with the piston cavity 37 is arranged in the piston cavity 37, a piston rod 4 in an integrated structure with the piston 41 is arranged in the center of the top of the piston 41, the upper end of the piston rod 4 extends out of the shell, two sides of the shell are respectively provided with a connector 36 for connecting a stem cell liquid conveying pipeline, a liquid inlet pipe 361 communicated with the buffer cavity 33 is arranged in the connector 36, the middle part of the liquid inlet pipe 361 is an expansion section 362, two sides of the expansion section 362 are in an arc structure, a control valve 363 is arranged in the expansion section 362, and a knob 364 extending, the control valve 363 can be rotated by rotating the knob 364 so as to control the on-off state of the whole liquid inlet pipe 361; when stem cells are conveyed into the bag body 1, the connector 36 is connected with a stem cell liquid conveying pipeline, the control valve 363 on the other side is closed, the piston rod 4 is pulled upwards, negative pressure is generated in the buffer cavity 33 in the rising process of the piston 41 to enable stem cell liquid to enter the buffer cavity 33, conveying amount is measured through the scale mark 32 on the transparent window 31, the piston rod 4 is stopped being pulled upwards after the storage amount is reached, the liquid inlet pipes 361 on two sides are sealed, the piston rod 4 is pushed downwards, the stem cell liquid is conveyed into the bag body 1 while the piston 41 moves downwards, the connection between the bag body 1 and the quantitative conveyor 3 is disconnected after the conveying is completed, and redundant air in the bag body 1 is discharged through the expansion of the inner air bag 2 and then is sealed.
Still be equipped with label column 17 on the 1 outer wall of the bag body, label column 17 is used for plugging in and corresponds the label in order to play the convenient function of discerning after a plurality of storage bags are concentrated and are deposited.
Example 2:
on the basis of embodiment 1, the threaded sleeve 35 has a cannula 34 inside which is communicated with the buffer chamber 33, and a check valve is arranged in the cannula 34, wherein the check valve in the cannula 34 is closed when negative pressure is generated in the buffer chamber 33, and the check valve is opened when the buffer chamber 33 supplies the stem cell liquid into the bag body 1, thereby ensuring accurate quantitative operation when the buffer chamber 33 is replenished with the stem cell liquid.
It is obvious to a person skilled in the art that the invention is not restricted to details of the above-described exemplary embodiments, but that it can be implemented in other specific forms without departing from the spirit or essential characteristics of the invention. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein. Any reference sign in a claim should not be construed as limiting the claim concerned.
Furthermore, it should be understood that although the present description refers to embodiments, not every embodiment may contain only a single embodiment, and such description is for clarity only, and those skilled in the art should integrate the description, and the embodiments may be combined as appropriate to form other embodiments understood by those skilled in the art.
Claims (5)
1. The utility model provides a cell storage bag with recognition function, includes the bag body (1) and passes through quantitative conveyer (3) of connection structure installation with the bag body (1), bag body (1) comprises integrated into one piece's outer bag (11) and inner bag (12), for filling intermediate layer (13) that have the coolant liquid between outer bag (11) and inner bag (12), outer bag (11) top has convenient link (14) that carry out the device whole and hang up, its characterized in that, bottom has interior gasbag (2) in inner bag (12), and interior gasbag (2) inside cavity is linked together through connecting pipe (22) of cartridge at bag body (1) bottom central authorities and inflation and deflation port (21) that are located bag body (1) below.
2. The cell storage bag with the identification function according to claim 1, wherein the connection structure comprises a delivery pipe (15) positioned at the top of the bag body (1) and a threaded sleeve (35) positioned at the bottom of the quantitative conveyor (3), the lower end of the delivery pipe (15) is communicated with the inside of the inner bag (12), the top of the delivery pipe (15) is provided with a connection threaded pipe (16), and the connection threaded pipe (16) is in threaded connection with the threaded sleeve (35).
3. The cell storage bag with the identification function according to claim 1 or 2, wherein the quantitative conveyor (3) is used for quantitatively conveying stem cells into the bag body (1), the main body of the quantitative conveyor (3) is a square shell with a buffer cavity (33) inside, a transparent window (31) with scale marks (32) is arranged on the outer wall of the shell, a piston cavity (37) is connected to the top of the buffer cavity (33), a piston (41) slidably connected to the piston cavity (37) is arranged in the piston cavity (37), a piston rod (4) integrated with the piston (41) is arranged in the center of the top of the piston (41), the upper end of the piston rod (4) extends out of the shell, connectors (36) are respectively arranged on two sides of the shell, a liquid inlet pipe (361) communicated with the buffer cavity (33) is arranged in the connectors (36), and an expansion section (362) is arranged in the middle of the liquid inlet pipe (361), two sides of the expansion section (362) are of circular arc structures, a control valve (363) is arranged in the expansion section (362), and a knob (364) extending upwards out of the top of the connector (36) is connected to the control valve (363).
4. The cell storage bag with identification function as claimed in claim 1 or 2, wherein the outer wall of the bag body (1) is further provided with a label column (17).
5. The cell storage bag with identification function according to claim 2, wherein said threaded sleeve (35) has a cannula (34) communicating with the buffer chamber (33) inside, and a check valve is provided in the cannula (34).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920082670.0U CN209988343U (en) | 2019-01-18 | 2019-01-18 | Cell storage bag with recognition function |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920082670.0U CN209988343U (en) | 2019-01-18 | 2019-01-18 | Cell storage bag with recognition function |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN209988343U true CN209988343U (en) | 2020-01-24 |
Family
ID=69287929
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201920082670.0U Expired - Fee Related CN209988343U (en) | 2019-01-18 | 2019-01-18 | Cell storage bag with recognition function |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN209988343U (en) |
-
2019
- 2019-01-18 CN CN201920082670.0U patent/CN209988343U/en not_active Expired - Fee Related
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| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20200124 |