CN209890647U - A constant temperature sample incubator for cell therapy - Google Patents
A constant temperature sample incubator for cell therapy Download PDFInfo
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- CN209890647U CN209890647U CN201920330626.7U CN201920330626U CN209890647U CN 209890647 U CN209890647 U CN 209890647U CN 201920330626 U CN201920330626 U CN 201920330626U CN 209890647 U CN209890647 U CN 209890647U
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Abstract
The utility model provides a constant temperature sample incubator for cell therapy, which comprises a box body and a box door, wherein the box body is provided with a control mechanism, the top in the box body is provided with a plurality of light source mechanisms, each light source mechanism comprises a straight cylinder and a piston rod I sleeved in the straight cylinder, the lower end of the piston rod extends out of the straight cylinder and is fixedly connected with a lamp tube, the lower part in the box body is provided with a culture mechanism corresponding to the light source mechanism, the culture mechanism comprises a placing frame, a placing plate inserted in the sliding way and placed in the placing frame, the rear end of the placing frame is rotationally connected on the inner wall of the box body, a plurality of grooves are arranged on the placing plate in an array manner, the, the distance of the light source, the wavelength of the light source, the illumination quantity and the like can be adjusted according to the requirements, various culture conditions can be built in the same culture box, the applicability is strong, the inclination angle of the culture dish is adjustable, the culture dish is suitable for slant culture with different requirements, and the comprehensive culture effect is good.
Description
Technical Field
The invention relates to the technical field of cell culture equipment, in particular to a constant-temperature sample incubator for cell therapy.
Background
Cell therapy is a treatment method for repairing tissues and organs by using autologous (or allogeneic) adult cells (or stem cells) of a patient, and is widely used for diseases such as bone marrow transplantation, late cirrhosis, femoral head necrosis, malignant tumors, myocardial infarction and the like. Current therapeutic cells include: NK, gamma delta T, CD3AK, DC-CIK and the like, and the conditions of the curative effect, specificity, overall effective rate, side effect reaction and the like of the traditional Chinese medicine are gradually improved. Cytokine or monoclonal antibody-activated immune cells, dendritic antigen-presenting cells, adult tissue mesenchymal cells, blood-lymph stem cells, artificially induced pluripotent stem cells, and the like.
The cell therapy is generally to take out autologous cells, culture them for 3-5 weeks, and then transplant or inject them into autologous affected parts to achieve the purpose of repairing damaged cells, and the cell therapy has long-term effect, and the cells can release the self healing and regeneration ability to treat diseases.
In the process of cell therapy, autologous cells need to be taken out and cultured in vitro, and then transplanted or injected back to the autologous focus part after a period of time, the step of in vitro culture is one of the key points of cell therapy, and in order to ensure good cell therapy effect, it is necessary to design an efficient cell sample incubator.
SUMMERY OF THE UTILITY MODEL
To the problem that exists, the utility model provides a constant temperature sample incubator for cell therapy, the device is adjusted the flexibility good, can adjust light source distance, light source wavelength, illumination volume etc. as required, can build multiple culture condition in the same incubator, and the suitability is strong, and culture dish inclination is adjustable, is applicable to the inclined plane culture of different requirements, and comprehensive culture is effectual.
In order to achieve the above object, the present invention adopts the following technical solutions:
a constant-temperature sample incubator for cell therapy comprises a incubator body, a chamber door hinged to one side of the incubator body, a control mechanism arranged on the incubator body, a controller, a temperature adjusting button, a temperature display screen, a humidity adjusting button, a humidity display screen and a carbon dioxide concentration adjusting button, carbon dioxide concentration display screen, the top is equipped with a plurality of light source mechanisms in the box, light source mechanism includes straight section of thick bamboo, cup joint the piston rod one in straight section of thick bamboo, piston rod lower extreme extends to straight section of thick bamboo and outside and fixed even have the fluorescent tube, the lower part is equipped with cultivates the mechanism corresponding to light source mechanism in the box, cultivate the mechanism including placing the frame, the thing board of putting in the frame is pegged graft and is placed in the slip, it rotates to place the frame rear end and connects on the box inner wall, it is equipped with the spout to place frame both sides limit looks side, it is equipped with the protruding edge with the spout adaptation to put thing board both sides.
Preferably, at least 3 light source units and at least 3 culture units are provided.
Preferably, the upper end of the straight cylinder is communicated with a transverse pipe, a second piston rod is arranged in the transverse pipe in a sliding mode, the outer end of the piston rod extends out of the transverse pipe and is connected with a handle, the lower end of the straight cylinder and the outer end of the transverse pipe are arranged in an unsealed mode, and limiting blocks are arranged on the inner wall of the lower end of the straight cylinder and the inner wall of the outer end of the transverse.
Preferably, a lamp tube switch is arranged on the side wall of the lower part of the piston rod, a cavity is arranged in the lower part of the piston rod, a storage battery is arranged in the cavity, and the storage battery is electrically connected with the lamp tube and the lamp tube switch through electric wires.
Preferably, the placing frame is of an n-shaped structure, the rear end of the placing frame is fixedly connected with an arbitrary stopping shaft, a bearing seat matched with the arbitrary stopping shaft is arranged on the inner wall of the rear side of the box body, and the placing frame is rotatably inserted on the bearing seat through the arbitrary stopping shaft.
Preferably, the front end of the object placing plate is provided with a handle, and a culture dish is placed in the groove.
Preferably, the inner wall of the box body is provided with a temperature probe, a humidity probe and a carbon dioxide concentration probe.
Preferably, place frame both sides limit top and be equipped with slewing mechanism and locating lever respectively, slewing mechanism corresponds the fixed column that sets up including back and forth, and it has the axostylus axostyle to rotate between the fixed column upper end, and it has 2 at least branches to correspond annular array around on the axostylus axostyle outer wall, is equipped with the reel around two branches in the front and back, through clockwork spring around being equipped with different filter coatings in the reel, and filter coating outer end side is opened and is equipped with 2 at least locating holes, is equipped with on the locating lever and.
Due to the adoption of the technical scheme, the beneficial effects of the utility model are that: the utility model discloses the device is adjusted the flexibility good, and the light source mechanism of top, the cultivation mechanism of below all can adjust as required, and the adjustment that can carry out the pertinence to light source distance, light source wavelength, illumination volume etc. is carried out to a plurality of different filtering films on the cooperation slewing mechanism, can build multiple culture condition in the same incubator, and the suitability is strong, and culture dish inclination is adjustable, is applicable to the inclined plane cultivation of different requirements, and the comprehensive culture is effectual.
Drawings
FIG. 1 is a schematic structural view of the present invention;
FIG. 2 is an enlarged view of the position A of the present invention;
FIG. 3 is a side view of the light source mechanism of the present invention;
FIG. 4 is a top view of the placement frame of the present invention;
FIG. 5 is a top view of the object placing plate of the present invention;
FIG. 6 is a schematic view of a control mechanism of the present invention;
FIG. 7 is a schematic block diagram of a control circuit of the present invention;
in the figure: the device comprises a box body 1, a box door 2, a control mechanism 3, a controller 301, a temperature adjusting button 302, a temperature display screen 303, a humidity adjusting button 304, a humidity display screen 305, a carbon dioxide concentration adjusting button 306, a carbon dioxide concentration display screen 307, a light source mechanism 4, a straight cylinder 401, a piston rod I402, a lamp tube 403, a transverse tube 404, a piston rod II 405, a handle 406, a lamp tube switch 407, a culture mechanism 5, a placement frame 501, a placement plate 502, a groove 503, a rotating mechanism 6, a fixed column 601, a shaft 602, a supporting rod 603, a winding drum 604, a positioning rod 7 and a positioning hook 701.
Detailed Description
In order to make the purpose, technical solution and advantages of the embodiments of the present invention clearer, the embodiments of the present invention are combined with the following description to clearly and completely describe the technical solution in the embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by a person of ordinary skill in the art without creative efforts belong to the protection scope of the present invention.
Additional advantages, objects, and features of the invention will be set forth in part in the description which follows and in part will become apparent to those having ordinary skill in the art upon examination of the following or may be learned from practice of the invention.
A constant temperature sample incubator for cell therapy, as shown in figures 1 to 6, comprises a case body 1, a case door 2 hinged to one side of the case body 1, a control mechanism 3 arranged on the case body 1, the control mechanism 3 comprising a controller 301 (the controller can be selected from a single chip microcomputer, such as WCH SOP-16CH340G, UC3846N DIP-16KA3846 chip and the like), a temperature adjusting button 302, a temperature display screen 303, a humidity adjusting button 304, a humidity display screen 305, a carbon dioxide concentration adjusting button 306 and a carbon dioxide concentration display screen 307, when in use, the probe is controlled by the adjusting button to work, then signals are transmitted to the controller and displayed on the display screen, a plurality of light source mechanisms 4 are arranged on the inner top of the case body 1, the light source mechanisms 4 comprise a straight cylinder 401 and a piston rod 402 sleeved in the straight cylinder 401, the lower end of the piston rod 402 extends out of the straight cylinder 401 and is fixedly connected with a lamp tube 403 for providing light, the lower part is equipped with cultivation mechanism 5 corresponding to light source mechanism 4 in the box 1, cultivates mechanism 5 including placing frame 501, slip grafting and place the thing board 502 in the frame 501, places the frame 501 rear end and rotates and connect on the box 1 inner wall, places frame 501 both sides limit opposite side and is equipped with the spout, puts thing board 502 both sides and is equipped with the protruding edge with the spout adaptation, puts a plurality of recesses 503 of arranging in an array on the thing board 502.
Preferably, at least 3 light source units 4 and at least 3 culture units 5 are provided.
Preferably, the upper end of the straight tube 401 is communicated with a transverse tube 404 (the transverse tube and the straight tube are communicated and formed in an integral mode, and the inner air pressure is adjusted by pushing and pulling the piston rod II, so that the piston rod I can move up and down, namely the height of the bottom lamp tube can be adjusted), a piston rod II 405 is arranged in the transverse tube 404 in a sliding mode, the outer end of the piston rod II 405 extends to the outer portion of the transverse tube 404 and is connected with a handle 406, the lower end of the straight tube 401 and the outer end of the transverse tube 404 are arranged in an unsealed mode, limiting blocks are arranged on the inner wall of.
Preferably, the side wall of the lower part of the first piston rod 402 is provided with a lamp switch 407, the lower part of the first piston rod 402 is provided with a cavity, the cavity is internally provided with a storage battery, and the storage battery is electrically connected with the lamp 403 and the lamp switch 407 through electric wires. The lamp tube is independently supplied with power by a storage battery, or the wire access end of the lamp tube and the output end of the pin of the controller can be connected by a wire according to the condition, and a corresponding lamp tube adjusting button is arranged to give out a signal through the adjusting button and is controlled to be started by the controller.
Preferably, the placing frame 501 is of an n-shaped structure, the rear end of the placing frame 501 is fixedly connected with any stopping shaft, a bearing seat matched with any stopping shaft is arranged on the inner wall of the rear side of the box body 1, and the placing frame 501 is rotatably inserted on the bearing seat through any stopping shaft. The bearing block is fixedly arranged on the inner wall of the rear side of the box body. The placing frame can stop the rotating shaft at will to rotate as the axis, and the inclination angle of the placing frame is adjusted, so that the inclination degree of the culture dish placed on the placing frame is adjusted.
Preferably, a handle is arranged at the front end of the object placing plate 502, and a culture dish is placed in the groove 503. The object placing plate can be completely pulled out through the handle, and the object placing plate is convenient to take and install.
Preferably, the inner wall of the box body 1 is provided with a temperature probe, a humidity probe and a carbon dioxide concentration probe (not shown in the figure, electrically connected and matched with the control mechanism, and designed according to the standard of isolated cell culture).
Preferably, place frame 501 both sides limit top and be equipped with slewing mechanism 6 and locating lever 7 respectively, slewing mechanism 6 corresponds the fixed column 601 that sets up including the front and back, it has axostylus axostyle 602 to rotate between fixed column 601 upper end, it has 2 at least branches 603 to correspond annular array around on the axostylus axostyle 602 outer wall, be equipped with reel 604 between two branches 603 in the front and back, around being equipped with different filter coatings through clockwork spring in the reel 604, the filter coating outer end side is opened and is equipped with 2 at least locating holes, be equipped with on the locating lever 7 with the location of. The reel is internally provided with a shaft lever for the filter coating to wind, and the side wall is provided with a strip-shaped opening for the filter coating to run through. Different filter films can provide filtering or different transmittance of light with different wavelengths, so as to adjust the wavelength and the illumination intensity of the light.
The utility model discloses the device is adjusted the flexibility good, and the light source mechanism of top, the cultivation mechanism of below all can adjust as required, and the adjustment that can carry out the pertinence to light source distance, light source wavelength, illumination volume etc. is carried out to a plurality of different filtering films on the cooperation slewing mechanism, can build multiple culture condition in the same incubator, and the suitability is strong, and culture dish inclination is adjustable, is applicable to the inclined plane cultivation of different requirements, and the comprehensive culture is effectual.
Details, structures, dimensions and principles not mentioned in the present application are all known in the art or can be obtained by simple selection of those skilled in the art, and are not described in detail. It is noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising an … …" does not exclude the presence of other identical elements in a process, method, article, or apparatus that comprises the element.
The above embodiments are only used to illustrate the technical solution of the present invention, and not to limit it; although the present invention has been described in detail with reference to the foregoing embodiments, it should be understood by those skilled in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some technical features may be equivalently replaced; such modifications and substitutions do not depart from the spirit and scope of the present invention in its corresponding aspects.
Claims (8)
1. The utility model provides a constant temperature sample incubator for cell therapy, includes box (1), articulated connect in chamber door (2) of box (1) one side, be equipped with control mechanism (3) on box (1), control mechanism (3) include controller (301), temperature regulation button (302), temperature display screen (303), humidity control button (304), humidity display screen (305), carbon dioxide concentration adjustment button (306), carbon dioxide concentration display screen (307), its characterized in that: the top is equipped with a plurality of light source mechanism (4) in box (1), light source mechanism (4) including straight section of thick bamboo (401), cup joint in piston rod (402) in straight section of thick bamboo (401), piston rod (402) lower extreme extends to straight section of thick bamboo (401) outer and fixed even have fluorescent tube (403), lower part is corresponding to in box (1) light source mechanism (4) are equipped with cultivates mechanism (5), cultivate mechanism (5) including placing frame (501), slip grafting with place thing board (502) in frame (501), place frame (501) rear end rotate connect in on box (1) inner wall, it is equipped with the spout to place frame (501) both sides limit laterad, put thing board (502) both sides be equipped with the protruding edge of spout adaptation, it arranges a plurality of recesses (503) on thing board (502) to put the array.
2. The thermostatted sample incubator for cell therapy according to claim 1, characterized in that: the number of the light source mechanisms (4) and the number of the culture mechanisms (5) are at least 3.
3. The thermostatted sample incubator for cell therapy according to claim 1, characterized in that: the intercommunication is equipped with violently pipe (404) in straight section of thick bamboo (401) upper end, it sets piston rod two (405) to slide in violently pipe (404), two (405) outer ends of piston rod extend to violently outside pipe (404) and be connected with handle (406), straight section of thick bamboo (401) lower extreme, violently pipe (404) outer end are the setting of not sealing, just straight section of thick bamboo (401) lower extreme inner wall, violently pipe (404) outer end inner wall are equipped with the stopper.
4. The thermostatted sample incubator for cell therapy according to claim 1, characterized in that: the side wall of the lower part of the first piston rod (402) is provided with a lamp switch (407), the lower part of the first piston rod (402) is provided with a cavity, a storage battery is arranged in the cavity, and the storage battery is electrically connected with the lamp (403) and the lamp switch (407) through electric wires.
5. The thermostatted sample incubator for cell therapy according to claim 1, characterized in that: the novel multifunctional storage box is characterized in that the placement frame (501) is of an n-shaped structure, the rear end of the placement frame (501) is fixedly connected with an arbitrary stopping rotating shaft, a bearing seat matched with the arbitrary stopping rotating shaft is arranged on the inner wall of the rear side of the box body (1), and the placement frame (501) is rotatably inserted into the bearing seat through the arbitrary stopping rotating shaft.
6. The thermostatted sample incubator for cell therapy according to claim 1, characterized in that: the front end of the object placing plate (502) is provided with a handle, and a culture dish is placed in the groove (503).
7. The thermostatted sample incubator for cell therapy according to claim 1, characterized in that: the inner wall of the box body (1) is provided with a temperature probe, a humidity probe and a carbon dioxide concentration probe.
8. The thermostatted sample incubator for cell therapy according to claim 1, characterized in that: it is equipped with slewing mechanism (6) and locating lever (7) respectively to place frame (501) both sides limit top, slewing mechanism (6) correspond fixed column (601) that sets up including the front and back, it has axostylus axostyle (602) to rotate between fixed column (601) upper end even, it has 2 at least branch (603) to correspond annular array around on the axostylus axostyle (602) outer wall, is equipped with reel (604) between two front and back branch (603), around being equipped with different filter coatings through clockwork spring in reel (604), filter coating outer end side is opened and is equipped with 2 at least locating holes, be equipped with on locating lever (7) with locating hole adaptation colludes (701).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920330626.7U CN209890647U (en) | 2019-03-15 | 2019-03-15 | A constant temperature sample incubator for cell therapy |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920330626.7U CN209890647U (en) | 2019-03-15 | 2019-03-15 | A constant temperature sample incubator for cell therapy |
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| Publication Number | Publication Date |
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| CN209890647U true CN209890647U (en) | 2020-01-03 |
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| CN201920330626.7U Active CN209890647U (en) | 2019-03-15 | 2019-03-15 | A constant temperature sample incubator for cell therapy |
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