CN209863820U - Clinical non-ocular-movement resting potential measuring system - Google Patents
Clinical non-ocular-movement resting potential measuring system Download PDFInfo
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- CN209863820U CN209863820U CN201821297700.1U CN201821297700U CN209863820U CN 209863820 U CN209863820 U CN 209863820U CN 201821297700 U CN201821297700 U CN 201821297700U CN 209863820 U CN209863820 U CN 209863820U
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Abstract
The utility model provides a clinical non-ocular resting potential measuring system, which belongs to the technical field of electrophysiology. This system includes inductor, alternately gathers analog switch circuit, amplifier module, singlechip, host computer, light source, wherein: the cross acquisition analog switch circuit comprises two CD4052 digital control analog switches and a TLP521-4 photoelectric coupling switch for isolation; the left eye electrode and the right eye electrode are respectively connected to pins of input ends of respective CD4052 digital control analog switches, and the two CD4052 digital control analog switches are respectively connected with the preamplifier; an IO pin of a 51 single chip microcomputer is connected with an input pin of a TLP521-4 photoelectric coupling switch, and the on/off of the TLP521-4 is controlled by outputting high/low level; the output pin of the TLP521-4 photoelectric coupling switch is connected with a control pin (A, B) of the CD 4052; when TLP521-4 is turned on, the control pin (A, B) of CD4052 is at low level; when off, the level of the control pin (A, B) of CD4052 is high; the upper computer controls the cross acquisition analog switch circuit and the light source through the single chip microcomputer.
Description
Technical Field
The utility model relates to an eye resting potential (OSP) measuring technology, belonging to the field of electrophysiology.
Background
The eyeball is known as a dipole like a battery, and a potential difference exists between the front end and the rear end. This potential difference originates in the pigmented epithelial layer of the retina of the eye, and this potential is physiologically called the resting potential (OSP) of the eye. Medically, retinal function can be evaluated and fundus disease diagnosed by measuring the amount of OSP going up and down. Closest to prior art implementations and the limitations that exist: for years, the traditional method of EOG is to record OSP by a pair of electrodes placed on the skin surfaces of inner and outer canthus of the palpebral fissure in a way that the level of an eyeball jumps to and from, and record a pair of positive and negative potential values of the eyeball by using the same angle of the left and right sides of the eyeball controlled by the eyeball rotated by a patient. However, the OSP recorded by this method is unstable, and the recorded result is unstable due to factors such as different eye jump angles and the degree of cooperation of the examination, and the reliability of the examination result is affected.
Disclosure of Invention
The utility model aims to overcome the prior art not enough, disclose a novel eye resting potential (OSP) survey system that can supply laboratory and clinical application. The utility model can replace the traditional OSP measuring mode in the eye movement electro-oculogram (M-EOG) record.
The principle of the utility model is to design a system implementation and a specific circuit by adopting cross sampling in electricity to replace eye movement recording, thereby realizing that the eye movement recording OSP is replaced by the eye movement recording OSP.
The utility model discloses the technical scheme sign that needs the protection does:
the utility model provides a clinical non-eye movement resting potential survey system which characterized in that, this system includes inductor, alternately gathers analog switch circuit, amplifier module, singlechip, host computer, light source, wherein:
the sensor is a left eye electrode and a right eye electrode and is used for collecting an electric signal OSP without eye movement;
the cross acquisition analog switch circuit comprises two CD4052 digital control analog switches and a TLP521-4 photoelectric coupling switch for isolation;
the CD4052 digital control analog switch comprises a first input terminal pin (12, 14, 15, 11), a second input terminal pin (1, 2, 3, 4), a first output terminal pin 13, a second output terminal pin 3 and a control pin (A, B);
the TLP521-4 photoelectric coupled switch comprises a control pin (A, B);
the amplifier module is formed by connecting a preamplifier, an intermediate amplifier and a post-amplifier in series, wherein the preamplifier comprises an amplifier channel 1 and an amplifier channel 2;
each CD4052 digital control analog switch is connected with an eye electrode inductor through an input end pin thereof, and is connected with an amplifier channel in the preamplifier through an output end pin thereof;
the left eye electrode and the right eye electrode are respectively connected with a first input end pin and a second input end pin of a CD4052 digital control analog switch, and a first output end pin 13 and a second output end pin 3 of the CD4052 digital control analog switch are respectively connected with an amplifier channel 1 and an amplifier channel 2 in a preamplifier to form two parallel positive and negative electrode connecting circuits;
the CD4052 digital control analog switch is connected with the TLP521-4 photoelectric coupling switch through a control pin, and an IO pin (P20-P23) of the 51 single chip microcomputer is connected with an input pin of the TLP521-4 photoelectric coupling switch to form a control circuit;
the 51 single chip microcomputer controls on/off of the TLP521-4 by outputting a high/low level, when the TLP521-4 is switched on, the level of a control pin (A, B) of the CD4052 is low, when the TLP521-4 is switched off, the level of a control pin (A, B) of the CD4052 is high, the first input terminal pins (12, 14, 15 and 11) are connected with the first output terminal pin 13 to respectively represent four on selections of X1, X2, X3 and X4, the second input terminal pins (1, 2, 3 and 4) are connected with the second output terminal pin 3 to respectively represent four on selections of Y1, Y2, Y3 and Y4, and the working mode is as follows: the pin X1 is conducted with the pin X13, the pin Y1 is conducted with the pin Y3, and the normal acquisition working state is achieved; the pin X2 is conducted with the pin X13, the pin Y2 is conducted with the pin Y3, and the pin is in a cross acquisition working state;
the amplifier module amplifies the collected electric signals;
the single chip microcomputer comprises an AD (analog-to-digital) conversion unit and an IO (input/output) control module, wherein the AD conversion unit is connected with a post-amplifier of the amplifier module, converts an analog signal into digital information and provides the digital information to a computer; the IO control module is connected with the light source and used for controlling the light conditions of the light source;
the upper computer controls the cross acquisition analog switch circuit and the light source through the single chip microcomputer.
The inductor is a disposable silver-silver chloride electrode.
Compared with the prior art, the utility model discloses beneficial effect:
1. by means of the present invention, a method is created that enables OSP to be obtained without "eye jump".
2. In addition to stability and reliability, safety and non-invasive examination of the human body is also contemplated for future clinical use.
3. Fatigue caused by eye jump is eliminated and recording time is shortened.
Drawings
Fig. 1 is a schematic diagram of a system provided by an embodiment of the present invention;
fig. 2 is a schematic diagram of an embodiment of the present invention, which provides a cross-sampling analog switch circuit;
fig. 3 is a circuit diagram of an existing amplifier according to an embodiment of the present invention.
Detailed Description
The technical solution of the feeding device for hazardous waste according to the present invention will be further described with reference to the following embodiments and accompanying drawings. The advantages and features of the present invention will become more apparent in conjunction with the following description.
It should be noted that the embodiments of the present invention have better practicability, and are not intended to limit the present invention in any form. The technical features or the combinations of the technical features described in the embodiments of the present invention should not be considered as isolated, and they may be combined with each other to achieve a better technical effect. The scope of the preferred embodiments of the present invention may also include other implementations, and this should be understood by those skilled in the art to which the embodiments of the present invention pertain.
Techniques, methods, and apparatus known to those of ordinary skill in the relevant art may not be discussed in detail but are intended to be part of the specification where appropriate. In all examples shown and discussed herein, any particular value should be construed as merely illustrative, and not limiting. Thus, other examples of the exemplary embodiments may have different values.
It is to be understood that the terms used in the present invention should be interpreted broadly, and the specific meanings of the terms used in the present invention should be understood as specific conditions by those skilled in the art, unless otherwise specified or limited.
The drawings of the utility model all adopt the very simplified form and all use the non-accurate proportion, only used for convenience, clearly assist the explanation the purpose of the embodiment of the utility model, not the limit condition that the utility model can be implemented. The modification of any structure, the change of the proportional relationship or the adjustment of the size should fall within the scope covered by the technical content of the present invention without affecting the effect of the present invention and the purpose achieved. And the same reference numerals appearing in the various drawings of the present invention denote the same features or components, which can be applied to different embodiments.
The main technical principles and components of the present assay system are provided as shown in fig. 1.
The measuring system comprises:
1. inductor
For acquiring the electrical signal OSP of the non-eye movement.
This example employs a disposable silver-silver chloride electrode. Is the prior art.
2. Cross acquisition analog switch
The analog switch of fig. 2 is a circuit that collects and transmits cross and non-cross signals.
The embodiment is realized by adopting two eye electrodes, two CD4052 digital control analog switches and a TLP521-4 photoelectric coupling switch for isolation.
The left eye electrode and the right eye electrode are respectively connected to a pin X2 and a pin Y2 of the input end of the respective CD4052 digital control analog switch, and the two CD4052 digital control analog switches are respectively connected with the preamplifier through a pin 13 and a pin 3.
An IO pin (P20-P23) of a 51 single chip microcomputer is connected with an input pin of a TLP521-4 photoelectric coupling switch, and the on/off of the TLP521-4 is controlled by outputting high/low level; the output pin of the TLP521-4 photoelectric coupling switch is connected with a control pin (A, B) of the CD 4052. When TLP521-4 is turned on, the control pin (A, B) of CD4052 is at low level; when off, the control pin (A, B) of CD4052 is high.
As shown in the CD4050 truth table of the previous figures, the level of the control pin of CD4052 selects the eye electrode signal that is communicated to the amplifier module.
The circuit realizes the function of controlling cross sampling by using the single chip microcomputer.
3. Amplifier module (prior art, figure 3)
The amplifier module of the system is an eye resting potential amplifier, is formed by connecting a preamplifier, an intermediate amplifier and a post amplifier in series, is used for recording electric signals with different frequencies and different potentials, protects the safety of a human body in recording, and is particularly used for collecting OSP.
The amplifier for the system is shown to have a total amplification of approximately 10000 times, in the order of 100, 8 and 12.5.
1) The preamplifier (floating portion) is composed of two stages of operational amplifiers. The first stage is low input end noise, high input impedance and high common mode rejection ratio; the second stage is a band pass filter with a low end of 0.05Hz and a high end of 10-100 Hz for supply.
2) The intermediate optical isolation amplifier adopts a linear optical coupling amplifier, can isolate 2500V voltage and is enough to protect the human safety during recording.
3) The post-stage amplifier (non-floating part) is composed of three parts: (1) the selectable 50Hz wave trap is used for limiting 50Hz interference; (2) the gain adjustment in-phase amplifier is adjustable in three steps, so that the total gain of the whole amplifier reaches 5000 times; (3) the follower is a low-impedance output for matching various displays.
4. Single chip microcomputer
The single chip microcomputer adopts a 51 single chip microcomputer and comprises an AD (analog-to-digital) conversion unit and an IO (input/output) control module, the AD conversion unit is connected with a post-amplifier of the amplifier module, analog signals are converted into digital information and provided for a computer, and the single chip microcomputer transmits the converted data to the computer through a USB (universal serial bus) data line; the IO control module is connected with the light source and used for controlling the light conditions of the light source.
5. Upper computer
The upper computer controls the collection and the light source through the single chip microcomputer.
Based on above utility model technical scheme, during specific application, the host computer in the system, for example adopt the computer, this computer can also possess control module software, biological electricity processing application software, database, demonstration output unit etc. as the host computer. The control software module controls an AD conversion module in the single chip microcomputer to complete rapid conversion from an analog signal to a digital signal, application software of the upper computer stores a digital signal waveform in a database, and detection parameters related to the acquired signal are recorded in the database and used for waveform comparison and analysis. When the method is applied specifically, corresponding application software can be developed to store the digital signal waveform in a database for comparison analysis of data and waveform.
Control software module, application software part, wait follow-up further development, perfect, do not regard as the utility model discloses technical scheme's component. Therefore, the software part designed and compiled in specific application is not the invention task which needs to be completed by the technical scheme of the utility model.
The above description is only for the purpose of describing the preferred embodiments of the present invention, and is not intended to limit the scope of the present invention in any way. Any changes or modifications of the above-described embodiments, which may be made by those skilled in the art based on the above-described disclosure, should be considered as equivalent effective embodiments, and all fall within the scope of the protection of the present invention.
Claims (2)
1. The utility model provides a clinical non-eye movement resting potential survey system which characterized in that, this system includes inductor, alternately gathers analog switch circuit, amplifier module, singlechip, host computer, light source, wherein:
the sensor is a left eye electrode and a right eye electrode and is used for collecting an electric signal OSP without eye movement;
the cross acquisition analog switch circuit comprises two CD4052 digital control analog switches and a TLP521-4 photoelectric coupling switch for isolation;
the CD4052 digital control analog switch comprises a first input terminal pin (12, 14, 15, 11), a second input terminal pin (1, 2, 3, 4), a first output terminal pin 13, a second output terminal pin 3 and a control pin (A, B);
the TLP521-4 photoelectric coupled switch comprises a control pin (A, B);
the amplifier module is formed by connecting a preamplifier, an intermediate amplifier and a post-amplifier in series, wherein the preamplifier comprises an amplifier channel (1) and an amplifier channel (2);
each CD4052 digital control analog switch is connected with an eye electrode inductor through an input end pin thereof, and is connected with an amplifier channel in the preamplifier through an output end pin thereof;
the left eye electrode and the right eye electrode are respectively connected with a first input end pin and a second input end pin of a CD4052 digital control analog switch, and a first output end pin (13) and a second output end pin (3) of the CD4052 digital control analog switch are respectively connected with an amplifier channel (1) and an amplifier channel (2) in a preamplifier to form two parallel positive and negative electrode connecting circuits;
the CD4052 digital control analog switch is connected with the TLP521-4 photoelectric coupling switch through a control pin, and an IO pin (P20-P23) of the 51 single chip microcomputer is connected with an input pin of the TLP521-4 photoelectric coupling switch to form a control circuit;
the 51 single chip microcomputer controls on/off of the TLP521-4 by outputting a high/low level, when the TLP521-4 is switched on, the level of a control pin (A, B) of the CD4052 is low, when the TLP521-4 is switched off, the level of a control pin (A, B) of the CD4052 is high, the first input terminal pins (12, 14, 15 and 11) are connected with the first output terminal pin 13 to respectively represent four on selections of X1, X2, X3 and X4, the second input terminal pins (1, 2, 3 and 4) are connected with the second output terminal pin 3 to respectively represent four on selections of Y1, Y2, Y3 and Y4, and the working mode is as follows: the pin X1 is conducted with the pin X13, the pin Y1 is conducted with the pin Y3, and the normal acquisition working state is achieved; the pin X2 is conducted with the pin X13, the pin Y2 is conducted with the pin Y3, and the pin is in a cross acquisition working state;
the amplifier module amplifies the collected electric signals;
the single chip microcomputer comprises an AD (analog-to-digital) conversion unit and an IO (input/output) control module, wherein the AD conversion unit is connected with a post-amplifier of the amplifier module, converts an analog signal into digital information and provides the digital information to a computer; the IO control module is connected with the light source and used for controlling the light conditions of the light source;
the upper computer controls the cross acquisition analog switch circuit and the light source through the single chip microcomputer.
2. The system of claim 1, wherein: the inductor is a disposable silver-silver chloride electrode.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821297700.1U CN209863820U (en) | 2018-08-13 | 2018-08-13 | Clinical non-ocular-movement resting potential measuring system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821297700.1U CN209863820U (en) | 2018-08-13 | 2018-08-13 | Clinical non-ocular-movement resting potential measuring system |
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| Publication Number | Publication Date |
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| CN209863820U true CN209863820U (en) | 2019-12-31 |
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| CN201821297700.1U Active CN209863820U (en) | 2018-08-13 | 2018-08-13 | Clinical non-ocular-movement resting potential measuring system |
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