CN209826670U - Retina imaging system - Google Patents
Retina imaging system Download PDFInfo
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- CN209826670U CN209826670U CN201920088689.6U CN201920088689U CN209826670U CN 209826670 U CN209826670 U CN 209826670U CN 201920088689 U CN201920088689 U CN 201920088689U CN 209826670 U CN209826670 U CN 209826670U
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Abstract
The utility model discloses a retina imaging system, include: the first modulation module is used for modulating light emitted by the light source into parallel light beams with light spots in a preset shape through the lens, and the light spots are positioned on the side edge of a preset axis; the predetermined axis refers to a path that a part of light for imaging in the light reflected by the retina travels; the second modulation module is used for modulating and compressing the light spots of the parallel light beams into a linear shape or a point shape through the lens; the scanning galvanometer is used for scanning and illuminating the retina by utilizing the compressed linear or point-shaped light beams, and the linear or point-shaped parallel light beams are incident to the eye along the side edge of a preset axis; the spectroscope is used for transmitting at least part of the linear or point-shaped parallel light beams to the scanning galvanometer and acquiring at least part of reflected light on a preset axis; and the imaging module is used for imaging the retina according to the reflected light on the preset axis. The system can solve the influence of stray light reflected by the cornea on an imaging result, and enables an imaging image to be clearer.
Description
Technical Field
The utility model relates to an optical imaging technical field, concretely relates to retina imaging system.
Background
As shown in fig. 1A, the eye includes a cornea, an iris, a lens, a vitreous body, and a retina, the iris enveloping the surface of the lens and forming a pupil for admitting light, on the side of the lens away from the retina, the cornea overlaying the surface of the pupil. The light of the external object sequentially passes through the cornea, the pupil, the crystalline lens and the vitreous body to reach the retina, and then the visual perception of the external object is realized. The retinal image of the eye is important information indispensable in ophthalmic diagnosis and treatment, and tracking the morphological change of the fundus retina in real time will contribute to early diagnosis and prevention of physical diseases. For example, observation of the fundus image allows diagnosis of fundus diseases and judgment of the disease state of other diseases, for example, cerebral infarction, cerebral hemorrhage, cerebral arteriosclerosis, hypertension, diabetes, and the like. The principle of the existing retinal imaging method is generally as follows: light emitted by the light source enters the eye after being modulated, the fundus retina reflects the light, reflected light is emitted from the cornea and enters the imaging system after being modulated, and then the imaging system acquires an image of the retina. However, when the modulated incident light enters the eye, the cornea often reflects the incident light, that is, the cornea generates stray light and the light reflected by the fundus retina are mixed together and enter the imaging system, which further interferes the imaging result, reduces the quality of the imaging image, and further affects the diagnosis result of the disease condition.
To address the effects of stray light reflected by the cornea on the imaging results, the prior art proposes to separate the path of the illumination light from the path of light reflected by the retina that is available for imaging. Specifically, as shown in fig. 1B, a light beam passing through a circular spot (a spot on a cross section indicated by a broken straight line indicated by X1 is a circular spot in fig. 1B) is incident on the eye, and a shade Y is provided in the middle of the light beam to obtain a spot which is hollow in the middle (a spot on a cross section indicated by a broken straight line indicated by X2 is a hollow annular spot in fig. 1B), and the hollow area in the middle of the incident light beam is controlled to be located on the axis of the eye (indicated by a broken line OO' in fig. 1B). An imaging system is arranged between the shielding object Y and the eye and on the axis of the eye, so that stray light reflected by the cornea cannot be mixed when reflected light of an incident beam reflected by the fundus retina exits from the axis of the eye and enters the imaging system, and the imaging quality can be improved.
However, the inventor finds that although the method can solve the influence of the stray light reflected by the cornea on the imaging result, the definition of the imaging image is reduced.
Disclosure of Invention
In view of this, the embodiment of the present invention provides a retinal imaging system to solve the problem of low definition of the imaging image in the prior art.
According to a first aspect, embodiments of the present invention provide a retinal imaging system, comprising: the first modulation module is used for modulating light emitted by the light source into parallel light beams with light spots in a preset shape through a lens, and the light spots in the preset shape are positioned on the side edge of a preset axis; the predetermined axis refers to a path which is traversed by part of light which is reflected by the retina and is used for imaging after the part of light exits from the eye; the second modulation module is used for modulating and compressing the light spots of the parallel light beams into linear or point-shaped parallel light beams through a lens, and the linear or point-shaped parallel light beams are positioned on the side of the preset axis; the scanning galvanometer is used for scanning and illuminating the retina by utilizing the compressed linear or point-shaped light beams, and the linear or point-shaped parallel light beams are incident to the eye along the side edge of the preset axis; a beam splitter that reflects a portion of the light beam and transmits another portion of the light beam; the spectroscope is arranged on a light path between the second modulation module and the scanning galvanometer and used for transmitting at least part of the linear or point-shaped parallel light beams to the scanning galvanometer and acquiring at least part of reflected light on the preset axis; and the imaging module is used for imaging the retina according to the reflected light on the preset axis.
Optionally, the first modulation module includes: the light emitted by the light source enters from two right-angle surfaces of the right-angle prism and exits from the inclined surface; and the lens is used for converting the light emitted from the inclined plane into parallel beams.
Optionally, the first modulation module includes: the light emitted by the light source enters from the plane of the conical lens and exits from the conical surface; and the lens is used for converting the light emitted by the conical surface into parallel beams.
Optionally, the lens comprises a convex lens.
Optionally, the lens further includes a fresnel lens disposed on a light path in front of or behind the convex lens.
Optionally, the second modulation module comprises a cylindrical lens or a cylindrical mirror.
Optionally, the system further comprises: and the light condensation module is arranged on a light path between the scanning galvanometer and the eyes and used for converging the light emitted by the scanning galvanometer at the pupil.
The embodiment of the utility model provides a retina imaging system, the light modulation who transmits the light source becomes the parallel light beam of facula for predetermined shape earlier through lens, the parallel light beam modulation compression of this predetermined shape is the linear or punctiform parallel light beam with this predetermined shape of rethread lens, in this process, the energy of light has almost no loss, and linear or punctiform light beam energy after the modulation compression is stronger, thereby when utilizing linear or punctiform light beam after the modulation compression to scan the illumination through scanning galvanometer, the holistic intensity of illumination of retina is stronger, make the reverberation of retina stronger, consequently, the image is comparatively clear.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the embodiments or the technical solutions in the prior art will be briefly described below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without creative efforts.
FIG. 1A shows a schematic view of the structure of an eye;
FIG. 1B shows a schematic diagram of a prior art retinal imaging method;
fig. 2A shows a schematic diagram of a retinal imaging system according to an example of the present invention;
fig. 2B shows a schematic diagram of a retinal imaging system according to an example of the present invention;
fig. 3A to 3F are schematic views showing a light spot of a predetermined shape;
FIGS. 4A-4C are schematic diagrams illustrating modulation of a compressed linear or point-like spot;
fig. 5A shows a schematic diagram of the operation of a first modulation module and a second modulation module according to an example of the present invention;
fig. 5B shows a schematic diagram of the principle of action of another first modulation module and a second modulation module according to an example of the present invention;
FIGS. 6A to 6C are schematic diagrams illustrating the principle of compressing a plane image into a line image when a lenticular lens is used;
fig. 7 shows a flowchart of a retinal imaging method according to an embodiment of the present invention.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, but not all, embodiments of the present invention. Based on the embodiments in the present invention, all other embodiments obtained by those skilled in the art without creative efforts belong to the protection scope of the present invention.
The inventors have found that the reason for the reduced sharpness of the imaged image in the prior art is the loss of energy in the illumination beam due to the central portion of the illumination beam being blocked. Since the illumination beam and the reflected beam of the retina are themselves weak, the energy loss of the illumination beam has a large influence on the image sharpness.
Example one
The embodiment of the utility model provides a retina imaging system. As shown in fig. 2A, the system includes a first modulation module, a second modulation module, a scanning galvanometer, a beam splitter, and an imaging module.
The first modulation module is used for modulating light emitted by the light source into parallel light beams with light spots in a preset shape through the lens, and the light spots in the preset shape are located on the side of the preset axis. The predetermined axis in the present application refers to a path that a part of light for imaging after exiting from the eye among light reflected by the retina, as shown by a straight line with an arrow exiting from the eye direction in fig. 2A.
For example, the light spot on the cross section shown by the broken straight line indicated by X1 in fig. 2A may have any shape as shown in fig. 3A to 3F. In fig. 3A to 3F, black dots indicate positions of predetermined axes, and dot-filled regions indicate light spots. It can be seen that the predetermined shaped spot may be axisymmetric or centrosymmetric about the predetermined axis, or may not be symmetric about the predetermined axis, as long as the predetermined shaped spot is located on the side of the predetermined axis.
The first modulation module is used for modulating the light emitted by the light source into a parallel light beam with a light spot in a preset shape by using a lens, and the lens is usually in a more regular shape. To reduce the overall structural complexity of the first modulation module, the light emitted by the light source should be a parallel beam. If the light emitted by the light source itself is a radioactive light beam which is scattered around the light source, it is difficult to modulate the radioactive light beam into a parallel light beam by a lens with a regular shape, and at this time, a collimating lens may be disposed between the light source and the first modulation module to modulate the radioactive light beam into a parallel light beam, so that the incident light of the first modulation module is a parallel light beam.
The second modulation module is used for modulating and compressing the light spots of the parallel light beams into linear or point-shaped parallel light beams through the lens, and the linear or point-shaped parallel light beams are positioned on the side of the preset axis.
For example, the light spot on the cross section shown by the broken straight line indicated by X2 in fig. 2A may have a shape as shown in fig. 4A to 4C. In fig. 4A and 4B, black dots indicate positions of predetermined axes, and thick solid lines indicate that the shapes of light spots of parallel light beams after modulation and compression are linear; one of the two black dots in fig. 4C indicates the position of the predetermined axis, and the other indicates that the spot of the parallel light beam after modulation and compression is point-shaped.
The scanning galvanometer is used for scanning and illuminating the retina by utilizing the compressed linear or point-shaped light beams, and the linear or point-shaped parallel light beams are incident to the eye along the side edge of the preset axis.
The scanning galvanometer is an existing device and is provided with a reflective mirror, light beams can be reflected to retina so as to realize illumination, and in the reflection process, the scanning galvanometer can adjust the reflection angle of the reflective mirror in one direction or two directions so as to realize scanning illumination. The scanning galvanometer can scan dozens of times in one direction in one second, and the speed is very high. These functions of the scanning galvanometer are prior art and will not be described in detail herein.
When the light spots of the compressed light beams are linear, the scanning galvanometer scans back and forth in one direction to realize the integral scanning illumination of the retina; when the light spots of the compressed light beams are point-shaped, the scanning galvanometer can scan back and forth in two mutually perpendicular directions, so that the integral scanning illumination of the retina is realized. The reflected light of the retina can be reflected by the reflecting mirror of the scanning galvanometer after exiting from the eye and continuously propagates along the preset axis.
The beam splitter is an optical system capable of splitting a beam into a plurality of beams, and is generally formed by coating or specially processing a first surface of optical glass so that the first surface is in a semi-transparent state, and reflects part of the beams and transmits the other part of the beams. The spectroscope in the application is arranged on a light path between the second modulation module and the scanning galvanometer, and is used for transmitting at least part of linear or point-shaped parallel light beams to the scanning galvanometer and acquiring at least part of reflected light on a preset axis.
In the present application, as shown in fig. 2A, the reflecting surface of the spectroscope faces the exit end of the second modulation module, so that the spectroscope reflects the linear or point-shaped light beam emitted from the second modulation module and transmits the reflected light on the predetermined axis, and the imaging module is disposed on one side of the non-reflecting surface of the spectroscope and receives the reflected light (i.e., the reflected light of the retina) transmitted from the spectroscope and on the predetermined axis; alternatively, as shown in fig. 2B, the non-reflective surface faces the exit end of the second modulation module, so that the beam splitter transmits the linear or point-shaped light beam exiting from the second modulation module and reflects the reflected light on the predetermined axis, and the imaging module is disposed on the reflective surface side of the beam splitter and receives the reflected light on the predetermined axis (i.e., the reflected light of the retina).
The imaging module is used for imaging the retina according to the reflected light on the preset axis (namely the reflected light of the retina).
The retina imaging system separates the illumination light path from the light path which is reflected by the retina and can be used for imaging, and can solve the influence of the stray light reflected by the cornea on the imaging result; and the light emitted by the light source is modulated into parallel light beams with light spots in a preset shape through the lens, and then the parallel light beams in the preset shape are modulated and compressed into linear or point-shaped parallel light beams through the lens, so that the energy of the light is hardly lost in the process, the energy of the linear or point-shaped light beams after modulation and compression is strong, and the whole illumination intensity of the retina is strong when the linear or point-shaped light beams after modulation and compression are used for scanning and illumination through the scanning galvanometer, so that the reflected light of the retina is strong, and an imaged image is clear.
As an alternative to this embodiment, as shown in fig. 5A, the first modulation module includes a right angle prism and a lens. The right-angle prism has two right-angle surfaces and an inclined surface, and light emitted by the light source enters from the two right-angle surfaces of the right-angle prism and exits from the inclined surface. The lens is used for converting the light emitted from the inclined plane into parallel beams.
As a side-by-side alternative to the above alternative, the first modulation module includes an axicon and a lens, as shown in fig. 5B. The conical lens is provided with a plane and a conical surface (the conical surface can be a conical surface or a pyramid surface) arranged opposite to the plane, and light emitted by the light source enters from the plane of the conical lens and exits from the conical surface. The lens is used for converting the light emitted from the conical surface into parallel beams.
In both of the above-described alternative embodiments, the lens may comprise only convex lenses. Alternatively, the lens may be a combination of a convex lens and a fresnel lens, and the fresnel lens may be disposed on a light path behind the convex lens (i.e., the illumination light beam firstly passes through the convex lens and then passes through the fresnel lens), or may be disposed on a light path in front of the convex lens (i.e., the illumination light beam firstly passes through the fresnel lens and then passes through the convex lens). One surface of the Fresnel lens is a plane, and the other surface of the Fresnel lens is etched to form concentric circles from small to large. After passing through the convex lens, the light at the edge part of the convex lens is weaker, and the concentric design of the Fresnel lens ensures that the light emitted from the Fresnel lens is more uniform.
As an alternative to this embodiment, the second modulation module comprises a cylindrical lens or a cylindrical mirror. The principle of compressing a planar image into a line image when the second modulation module is a cylindrical lens is shown in fig. 6A to 6C, which is prior art and will not be described in detail herein.
Optionally, the retina imaging system further includes a light condensing module disposed on a light path between the scanning galvanometer and the eye, and condensing the light emitted from the scanning galvanometer at the pupil. For example, the light-condensing module may be a double cemented lens.
Example two
Fig. 7 shows a flowchart of a retinal imaging method according to an embodiment of the present invention, which can be implemented by, but not limited to, the retinal imaging system described in the first embodiment or any alternative embodiment thereof. As shown in fig. 7, the retinal imaging method includes the steps of:
s10: modulating light emitted by a light source into parallel light beams with light spots in a preset shape through a lens, wherein the light spots in the preset shape are positioned on the side of a preset axis; the predetermined axis refers to a path that a part of light reflected by the retina for imaging after exiting from the eye passes through.
As an alternative implementation manner of this embodiment, step S10 includes: the light emitted by the light source is modulated into parallel light beams with light spots in two patterns through a right-angle prism and a lens, and the two patterns are respectively positioned on two opposite sides of a preset axis. Please refer to embodiment one and fig. 5A specifically.
As an alternative implementation manner of this embodiment, step S10 includes: the light emitted by the light source is modulated into parallel light beams with annular light spots through the cone lens and the lens, and the preset axis is located in the annular hollow area. Please refer to embodiment one and fig. 5B.
S20: the light spot modulation of the parallel light beams is compressed into a linear or point shape through the lens, and the linear or point shape parallel light beams are positioned on the side of the preset axis.
S30: the compressed linear or point-shaped light beams are used for scanning and illuminating the retina, and the linear or point-shaped parallel light beams are incident to the eye along the side of a preset axis.
S40: reflected light on a predetermined axis is acquired and the retina is imaged accordingly.
The above steps can be understood by referring to the first embodiment, and are not described herein again.
The retina imaging system separates the illumination light path from the light path which is reflected by the retina and can be used for imaging, and can solve the influence of the stray light reflected by the cornea on the imaging result; and the light emitted by the light source is modulated into parallel light beams with light spots in a preset shape through the lens, and then the parallel light beams in the preset shape are modulated and compressed into linear or point-shaped parallel light beams through the lens, so that the energy of the light is hardly lost in the process, the energy of the linear or point-shaped light beams after modulation and compression is strong, and the whole illumination intensity of the retina is strong when the linear or point-shaped light beams after modulation and compression are used for scanning and illumination through the scanning galvanometer, so that the reflected light of the retina is strong, and an imaged image is clear.
Although the embodiments of the present invention have been described with reference to the accompanying drawings, those skilled in the art may make various modifications and variations without departing from the spirit and scope of the invention, and such modifications and variations fall within the scope defined by the appended claims.
Claims (7)
1. A retinal imaging system, comprising:
the first modulation module is used for modulating light emitted by the light source into parallel light beams with light spots in a preset shape through a lens, and the light spots in the preset shape are positioned on the side edge of a preset axis; the predetermined axis refers to a path which is traversed by part of light which is reflected by the retina and is used for imaging after the part of light exits from the eye;
the second modulation module is used for modulating and compressing the light spots of the parallel light beams into linear or point-shaped parallel light beams through a lens, and the linear or point-shaped parallel light beams are positioned on the side of the preset axis;
the scanning galvanometer is used for scanning and illuminating the retina by utilizing the compressed linear or point-shaped light beams, and the linear or point-shaped parallel light beams are incident to the eye along the side edge of the preset axis;
a beam splitter that reflects a portion of the light beam and transmits another portion of the light beam; the spectroscope is arranged on a light path between the second modulation module and the scanning galvanometer and used for transmitting at least part of the linear or point-shaped parallel light beams to the scanning galvanometer and acquiring at least part of reflected light on the preset axis;
and the imaging module is used for imaging the retina according to the reflected light on the preset axis.
2. The retinal imaging system of claim 1 wherein the first modulation module comprises:
the light emitted by the light source enters from two right-angle surfaces of the right-angle prism and exits from the inclined surface;
and the lens is used for converting the light emitted from the inclined plane into parallel beams.
3. The retinal imaging system of claim 1 wherein the first modulation module comprises:
the light emitted by the light source enters from the plane of the conical lens and exits from the conical surface;
and the lens is used for converting the light emitted by the conical surface into parallel beams.
4. The retinal imaging system of claim 2 or 3 wherein the lens comprises a convex lens.
5. The retinal imaging system of claim 4 wherein the lens further comprises a Fresnel lens disposed on the optical path in front of or behind the convex lens.
6. The retinal imaging system of claim 1 wherein the second modulation module comprises a cylindrical lens or a cylindrical mirror.
7. The retinal imaging system of claim 6, further comprising:
and the light condensation module is arranged on a light path between the scanning galvanometer and the eyes and used for converging the light emitted by the scanning galvanometer at the pupil.
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| CN201920088689.6U CN209826670U (en) | 2019-01-18 | 2019-01-18 | Retina imaging system |
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| CN201920088689.6U CN209826670U (en) | 2019-01-18 | 2019-01-18 | Retina imaging system |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112244761A (en) * | 2020-11-11 | 2021-01-22 | 中国科学院苏州生物医学工程技术研究所 | Portable cornea topographic map instrument |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112244761A (en) * | 2020-11-11 | 2021-01-22 | 中国科学院苏州生物医学工程技术研究所 | Portable cornea topographic map instrument |
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