CN209808515U - PID (proportion integration differentiation) controlled self-pressurization cryoablation system - Google Patents

PID (proportion integration differentiation) controlled self-pressurization cryoablation system Download PDF

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Publication number
CN209808515U
CN209808515U CN201822058418.4U CN201822058418U CN209808515U CN 209808515 U CN209808515 U CN 209808515U CN 201822058418 U CN201822058418 U CN 201822058418U CN 209808515 U CN209808515 U CN 209808515U
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China
Prior art keywords
storage tank
cryoablation
coolant
pid
coolant storage
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Withdrawn - After Issue
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CN201822058418.4U
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Chinese (zh)
Inventor
刁月鹏
赵奎文
姚佳陈
陈熙
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Cryofocus Medtech Shanghai Co Ltd
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Cryofocus Medtech Shanghai Co Ltd
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Priority to CN201822058418.4U priority Critical patent/CN209808515U/en
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Abstract

The application relates to a PID controlled self-pressurizing cryoablation system, which comprises a cryoablation device and a cryoablation catheter, wherein the cryoablation device comprises a control unit, a vacuum unit and a conveying unit, the conveying unit comprises an air source manufacturing device and an air path control device which are connected in sequence, the low-temperature conversion device comprises a Dewar flask and a heat exchanger, the air outlet end of the equipment connecting piece and the vacuum unit are respectively communicated with the cryoablation catheter, the air source manufacturing device is arranged in the Dewar flask, the air outlet end of the air source manufacturing device is communicated with the air inlet end of the air channel control device, the air source manufacturing device comprises a coolant storage tank, a pressure release valve communicated with the coolant storage tank, a coolant supplement joint communicated with the coolant storage tank and a heating device arranged in the coolant storage tank, the control unit comprises a PID (proportion integration differentiation) controller, and the heating device is electrically connected with the PID controller; the large and heavy pressure air tank of the external body is not needed, which is beneficial to saving the space of the cryoablation equipment.

Description

PID (proportion integration differentiation) controlled self-pressurization cryoablation system
Technical Field
The utility model relates to a cryoablation field, concretely relates to PID control's self-pressurization cryoablation system.
Background
Cryosurgical treatment is the proper freezing of the target biological tissue to be treated using extremely low temperatures and complex systems designed. Many of these systems use a working fluid that is connected to the cryoablation catheter from an external high pressure tank through a long flexible delivery tube, which typically has a large internal volume to hold enough working fluid to warrant a typical cryosurgical procedure. The gas cylinders are usually made of steel with a thick wall thickness, which makes them resistant to high pressures, but also makes them very bulky, and because of the large size and high pressure required, the pressurized gas cylinders are generally placed outside the cryoablation unit, which makes the system complicated to install and operate.
Chinese patent application No. cn201710027828.x discloses a cryoablation treatment system, comprising: a dewar part receiving a liquid refrigerant from the outside, a pressure vessel part, a heat exchange part, and a freezing unit; the pressure container part is arranged inside the Dewar bottle part, receives liquid refrigerant from the Dewar bottle part, and in the pressure container, the liquid refrigerant is converted into working fluid with higher pressure and temperature by the liquid-gas conversion expansion principle and is conveyed to a working fluid pipeline; the heat exchange component is arranged inside the Dewar flask component, is connected with the pressure container component through a working fluid pipeline, receives the working fluid from the pressure container component, converts the working fluid into working refrigerant and conveys the working refrigerant to a working refrigerant pipeline; the freezing unit is connected with the heat exchange component and used for receiving the working refrigerant, and the far end part of the freezing unit is a cold source releasing area of the working refrigerant. The refrigerant in the patent comes from an external gas tank, and the external gas tank needs a large space for arrangement, so that the installation and operation difficulty of the cryoablation system is increased.
Disclosure of Invention
An object of the utility model is to solve the problem that exists among the prior art, provide a built-in, practice thrift space of air supply and pressure control accurate PID control's from pressure boost cryoablation system.
The purpose of the utility model is realized through the following technical scheme:
the utility model provides a PID controlled from pressure boost cryoablation system, includes cryoablation equipment and cryoablation pipe, cryoablation equipment includes the control unit, vacuum unit and delivery unit, the delivery unit is including air supply manufacturing installation, gas circuit controlling means, low temperature conversion equipment and the equipment connecting piece that connects in order, the end of giving vent to anger of equipment connecting piece with the vacuum unit respectively with cryoablation pipe intercommunication, low temperature conversion equipment includes dewar bottle and heat exchanger, air supply manufacturing installation is set up in the dewar bottle, the end of giving vent to anger of air supply manufacturing installation with gas circuit controlling means's inlet end intercommunication, air supply manufacturing installation include coolant storage jar, with the relief valve of coolant storage jar intercommunication, with the coolant replenishment of coolant storage jar intercommunication connects, is set up heating device in the coolant storage jar, the control unit comprises a PID controller, the vacuum unit and the gas circuit control device are respectively electrically connected with the control unit, and the heating device is electrically connected with the PID controller.
The utility model discloses the purpose can also be further realized through following technical scheme:
preferably, the coolant storage tank is a vacuum insulated storage tank.
Preferably, the gas source manufacturing apparatus includes a liquid level measuring device electrically connected to the control unit, the liquid level measuring device being disposed inside the coolant storage tank, the liquid level measuring device being configured to detect a liquid level of the coolant in the coolant storage tank.
Preferably, the air supply manufacturing device comprises a pressure sensor, the pressure sensor is communicated with the coolant storage tank, the control unit further comprises an industrial personal computer assembly and a display electrically connected with the industrial personal computer assembly, the PID controller is electrically connected with the industrial personal computer assembly, the pressure sensor is electrically connected with the PID controller, and when the pressure in the coolant storage tank is not in the application range, the PID controller controls the working frequency of the heating device, so that the pressure in the coolant storage tank reaches the application range.
Preferably, the gas source manufacturing device includes a muffler, the pressure release valve is communicated with the muffler, when the pressure inside the coolant storage tank exceeds a limit pressure, the pressure release valve is opened, gas is discharged through the pressure release valve, and noise is reduced through the muffler.
Preferably, the air source manufacturing device comprises a coolant supplementary joint and an exhaust valve, the coolant supplementary joint and the exhaust valve are electrically connected with the control unit, and the coolant supplementary joint and the exhaust valve are in an interlocking structure. Preferably, the gas path control device comprises a freezing electromagnetic valve and a rewarming electromagnetic valve, the freezing electromagnetic valve is communicated with the gas inlet end of the heat exchanger, and the gas outlet end of the heat exchanger and the rewarming electromagnetic valve are respectively communicated with the inlet of the equipment connecting piece.
Preferably, the gaseous coolant in the coolant storage tank is nitrogen gas, and the liquid coolant in the coolant storage tank is liquid nitrogen.
Preferably, the coolant storage tank is a sealed device.
Compared with the prior art, the beneficial effects of the utility model are mainly embodied in that:
the utility model discloses a PID control's from pressure boost cryoablation system has removed outside gas pitcher, has developed a cryoablation equipment of taking single dewar bottle to the output in the coolant storage tank is high-pressure non-low temperature gas, and the controllability is high, realizes the controllable output of high-pressure low temperature fluid through the regulation to high-pressure non-low temperature gas, has avoided direct to dark low temperature fluid pressure boost and regulation difficulty. The cryoablation apparatus receives gaseous cryogen from a low pressure storage tank and automatically converts it to a desired ablative fluid, which is then delivered to the ablation assembly of the catheter. The utility model arranges the air source manufacturing device in the Dewar flask, and does not need to be externally connected with a heavy and bulky pressurized gas tank to provide an air source, which is beneficial to saving the space of the cryoablation equipment; the air source manufacturing device comprises a coolant storage tank, a heating device is arranged in the coolant storage tank, the coolant storage tank is pressurized by gasifying liquid coolant through the heating device, pressure is limited through a pressure release valve, safety is ensured, pressure change in the coolant storage tank is monitored in real time through a pressure sensor and fed back to a PID (proportion integration differentiation) controller, a target pressure value is set in the PID controller and compared with an actual pressure value to obtain a difference value, and the difference value is multiplied by a proportionality coefficient and then divided by the target pressure value to obtain the duty ratio of the work of the heating device. And calculating the slope of the curve of the difference and the time, adding a correction value, increasing the resistance coefficient of the curve, and finally enabling the slope to be 0, thereby carrying out accurate PID control, enabling the pressure of the cryoablation high-pressure low-temperature fluid output by the equipment to be accurate and controllable, avoiding obvious pressure fluctuation, greatly improving the safety and the operation convenience of the system, and simultaneously improving the utilization efficiency of cold energy.
Drawings
Fig. 1 is a schematic structural view of the self-pressurizing cryoablation system of the present invention;
FIG. 2 is a partially enlarged view of the conveying unit and the gas path control device shown in FIG. 1;
FIG. 3 is a partially enlarged schematic view of the gas source producing apparatus of FIG. 2;
FIG. 4 is a schematic diagram of one configuration of the heat exchanger of FIG. 2;
FIG. 5 is another schematic diagram of the heat exchanger of FIG. 2;
FIG. 6 is a schematic view of another construction of the heat exchanger of FIG. 2;
wherein: 1 is a cryoablation device, 2 is a cryoablation catheter, 11 is a housing, 12 is a control unit, 13 is a vacuum unit, 14 is a delivery unit, 121 is an industrial personal computer assembly, 122 is a display, 123 is a PID controller, 141 is an air source manufacturing device, 142 is an air path control device, 143 is a low-temperature conversion device, 144 is a device connector, 1411 is a coolant storage tank, 1412 is a coolant supplement connector, 1413 is a pressure relief valve, 1414 is a heating device, 1415 is a liquid level measuring device, 1416 is a pressure sensor, 1417 is a silencer, 1418 is an exhaust valve, 1422 is a refrigeration solenoid valve, 1423 is a rewarming solenoid valve, 1431 is a dewar, 1432 is a heat exchanger, a is an electrical communication interface, B is a coolant perfusion inlet, C is a coolant overflow outlet, D is a device connector inlet, and E is a coolant inlet.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more clearly understood, the present invention will be further described in detail with reference to the accompanying drawings and examples. It should be understood that the specific embodiments described herein are for purposes of illustration only and are not intended to limit the invention.
The first embodiment is as follows:
as shown in fig. 1, 2 and 3, the PID-controlled self-pressurizing cryoablation system of the present invention comprises a cryoablation apparatus 1 and a cryoablation catheter 2, wherein the cryoablation apparatus 1 comprises a housing 11, a control unit 12, a vacuum unit 13 and a delivery unit 14. The delivery unit 14 comprises a gas source manufacturing device 141, a gas path control device 142, a low temperature conversion device 143 and a device connecting piece 144 which are connected in sequence, the gas outlet end of the device connecting piece 144 and the vacuum unit 13 are respectively in fluid communication with the cryoablation catheter 2, the low temperature conversion device 143 comprises a dewar 1431 and a heat exchanger 1432, the gas source manufacturing device 141 is arranged in the dewar 1431, the gas outlet end of the gas source manufacturing device 141 is in fluid communication with the gas inlet end of the gas path control device 142, the gas source manufacturing device 141 comprises a coolant storage tank 1411, a pressure relief valve 1413 in fluid communication with the coolant storage tank 1411, a coolant supplementary joint 1412 in communication with the coolant storage tank 1411 and a heating device 1414 arranged in the coolant storage tank 1411, the control unit 12 comprises a PID controller 123, the vacuum unit 13 and the gas path control device 142 are respectively electrically connected with the control unit 12, the heating device 1414 is electrically connected to the PID controller 123.
The control unit 12 further comprises an industrial personal computer component 121 and a display 122 electrically connected with the industrial personal computer component 121, and the PID controller 123 is electrically connected with the industrial personal computer component 121. The pressure relief valve 1413 is a solenoid valve that is electrically connected to the industrial personal computer assembly 121. The gas circuit control device 142 further includes a freezing solenoid valve 1422 and a rewarming solenoid valve 1423, the freezing solenoid valve 1422 is communicated with the air inlet end of the heat exchanger 1432, the air outlet end of the heat exchanger 1432 and the rewarming solenoid valve 1423 are respectively communicated with the inlet D of the equipment connecting part 144, and the industrial personal computer assembly 121, the PID controller 123, the vacuum unit 13 and the conveying unit 14 are all disposed in the housing 11. The coolant storage tank 1411 is a vacuum insulated storage tank, the gaseous coolant in the coolant storage tank 1411 is nitrogen gas, and the liquid coolant in the coolant storage tank 1411 is liquid nitrogen. The gas source manufacturing device 141 further comprises a liquid level measuring device 1415, the liquid level measuring device 1415 and the heating device 1414 are arranged in the coolant storage tank 1411, and the heating device 1414 can select an electric heating wire or other equivalent components such as an electromagnetic coil. The air source manufacturing device 141 is arranged in the Dewar flask 1431, and an external heavy and large-volume pressurizing air tank is not needed to provide an air source, so that the space of the cryoablation equipment is saved due to the built-in structure of the air source, and the operation is convenient; the pressure upper limit is limited through the pressure relief valve 1413, safety is ensured, pressure change in the coolant storage tank 1411 is monitored in real time through the pressure sensor 1416 and fed back to the PID controller 123, a target pressure value is set in the PID controller 123 and compared with an actual pressure value to obtain a difference value, and the difference value is multiplied by a proportionality coefficient and then divided by the target pressure value, namely the duty ratio of the work of the heating device 1414. And calculating the slope of the curve of the difference and the time, adding a correction value, and increasing the resistance coefficient of the curve to enable the slope to be 0 finally, thereby carrying out accurate PID control, enabling the pressure of an air source to be controllable, and being beneficial to saving the freezing energy. In one embodiment, the coolant storage tank 1411 in the cryoablation system is a sealed device and can withstand higher pressure, and the temperature of the liquefaction point of the coolant can be changed by changing the pressure in the coolant storage tank 1411, so as to change the temperature of the ablation unit at the distal end of the cryoablation catheter 2, so as to meet the requirements of different focal tissues for the cryoablation temperature.
The utility model discloses an air supply manufacturing installation 141 includes coolant storage jar 1411, coolant that is connected with coolant storage jar 1411 respectively supplyes joint 1412, relief valve 1413, pressure sensor 1416, muffler 1417 and discharge valve 1418, is set up heating device 1414 and liquid level measurement device 1415 in coolant storage jar 1411, coolant supplyes joint 1412 pressure sensor 1416 discharge valve 1418 is connected with industrial computer subassembly 121 electricity, heating device 1414 with liquid level measurement device 1415 is connected with PID controller 123 electricity, coolant supplyes joint 1412 with discharge valve 1418 is interlocking structure. The liquid level measuring device 1415 is disposed inside the coolant storage tank 1411, in one embodiment, the liquid level measuring device 1415 is a thermometer which detects a liquid level of coolant in the coolant storage tank 1411 by a temperature difference between an upper and a lower coolant liquid levels, when the thermometer indicates a temperature of-190 ℃ or lower, it indicates that the coolant liquid level is higher than the thermometer position and no coolant needs to be added, when the thermometer indicates a temperature of-190 ℃ or higher, it indicates that the coolant liquid level is lower than the thermometer position and coolant needs to be added to the coolant storage tank 1411, the industrial personal computer module 121 controls the coolant supplement connection 1412 and the exhaust valve 1418 to be opened simultaneously, the coolant supplement connection 1412 communicates with the coolant storage tank 1411, the exhaust valve 1418 communicates with the atmosphere, and since the pressure at the coolant supplement connection 1412 is higher than the pressure at the exhaust valve 1418, coolant enters coolant storage tank 1411 from coolant inlet E through coolant make-up connection 1412 and vaporized coolant is vented to atmosphere through vent valve 1418, indicating that the dewar is full of coolant when liquid coolant is vented from vent valve 1418. And operating the industrial personal computer assembly 121, closing the coolant supplement joint 1412 and the exhaust valve 1418 at the same time, and finishing the coolant addition. When the PID controlled self-pressurization cryoablation system is used, a cryoablation catheter 2 is connected with cryoablation equipment 1 through an equipment connecting piece 144, then a display 122 interface is operated, a vacuum unit 13 is started, because the display 122 is electrically connected with an industrial personal computer component 121, and because the industrial personal computer component 121 is electrically connected with the vacuum unit 13, the vacuum unit 13 is started, the vacuum unit 13 is vacuumized, a doctor sends an ablation unit at the far end of the cryoablation catheter 2 to the focus position of a patient, the pressure required by cryotherapy is set, because a pressure sensor 1416 is arranged on a coolant storage tank 1411, when the pressure in the current coolant storage tank 1411 is lower than the set pressure, a heating device 1414 is started on the display 122 interface, because the display 122 is electrically connected with the industrial personal computer component 121, the industrial personal computer component 121 is electrically connected with a PID controller 123, and a heating device 1414 is electrically connected with the PID controller, and then the PID controller 123 is started, the pressure change in the coolant storage tank 1411 is monitored in real time through the pressure sensor 1416 and fed back to the PID controller 123, a target pressure value is set in the PID controller 123 and compared with an actual pressure value to obtain a difference value, and the difference value is multiplied by a proportionality coefficient and then divided by the target pressure value to obtain the duty ratio of the operation of the heating device 1414. And calculating the slope of the curve of the difference and the time, adding a correction value, and increasing the resistance coefficient of the curve to enable the slope to be 0 finally, thereby carrying out accurate PID control and enabling the pressure to be maintained in a required pressure value range.
At the time of the present high pressure setting pressure in the coolant storage tank 1411, since the relief valve 1413 is in fluid communication with the coolant storage tank 1411, the relief valve 1413 is actuated to relieve the pressure in the coolant storage tank 1411 and detect the pressure by the pressure sensor 1416, and when the pressure sensor 1416 detects that the pressure in the coolant storage tank 1411 is the same as the required pressure, the relief valve 1413 is closed.
The interface of the display 122 is operated, the vacuum unit 13 is started to vacuumize, the vacuum unit 13 is connected with the cryoablation catheter 2 through the equipment connecting piece 144, the cryoablation catheter 2 is vacuumized, when the vacuum degree meets the requirement, the refrigeration cycle is started, the display 122 is electrically connected with the industrial personal computer assembly 121, the industrial personal computer assembly 121 is electrically connected with the gas path control device 142, the refrigeration electromagnetic valve 1422 can be controlled to be opened through operating the interface of the display 122, the gaseous coolant enters the air inlet end of the heat exchanger 1432 from the air outlet end of the gas path control device 142, the gaseous coolant enters the heat exchanger 1432 soaked in the liquid coolant, the energy exchange is realized in the heat exchanger 1432, the gaseous coolant is changed into the liquid coolant, the liquid coolant flows into the cryoablation catheter 2 through the equipment connecting piece 144 through the heat exchanger 1432 due to the fluid communication between the air outlet end of the heat exchanger 1432 and the air inlet, the liquid coolant releases energy at the ablation unit at the distal end of the cryoablation catheter 2 to cryoablate the lesion.
After the cryoablation is completed, a doctor operates the interface of the display 122, the cryoablation cycle is closed, the cryoelectromagnetic valve 1422 is closed, then the doctor operates the interface of the display 122, the rewarming cycle is opened, the rewarming electromagnetic valve 1423 is opened, because the rewarming gas outlet end is communicated with the equipment connecting piece 144 through fluid, gaseous coolant enters the equipment connecting piece 144 from the rewarming gas outlet, the equipment connecting piece 144 is communicated with the cryoablation catheter 2 through fluid, the gaseous coolant enters the cryoablation catheter 2 through the equipment connecting piece 144 to rewarm lesion tissues, after the rewarming cycle is completed, the doctor operates the interface of the display 122, closes the rewarming, withdraws the cryoablation catheter 2, and the operation is finished.
Example two:
as shown in fig. 4, 5 and 6, the present embodiment is based on the first embodiment, and the difference from the first embodiment is only that: the heat exchanger 1432 is different in structure. As shown in fig. 4, the heat exchanger 1432 is a spiral pipe structure, which increases the heat exchange area of the gaseous coolant for energy exchange with the coolant in the dewar 1431, and the spiral pipe structure can effectively reduce the flow resistance of the coolant in the heat exchanger 1432; as shown in fig. 5, the heat exchanger 1432 has a horizontal serpentine structure, which increases the heat exchange area between the gaseous coolant and the liquid coolant in the dewar 1431, and can reduce the space consumption of the heat exchanger in the dewar 1431 as much as possible, thereby improving the system compactness; as shown in fig. 6, the heat exchanger 1432 has a vertical coil structure, which increases the heat exchange area between the gaseous coolant and the liquid coolant in the dewar 1431, improves the heat exchange efficiency, and can reduce the space consumption of the heat exchanger 1432 in the dewar 1431 as much as possible.
The above description is only exemplary of the present invention and should not be taken as limiting, and any modifications, equivalents, improvements, etc. made within the spirit and principles of the present invention should be included within the scope of the present invention.

Claims (8)

1. A PID-controlled self-pressurizing cryoablation system, characterized by: the cryoablation device comprises a cryoablation device (1) and a cryoablation catheter (2), wherein the cryoablation device (1) comprises a control unit (12), a vacuum unit (13) and a delivery unit (14), the delivery unit (14) comprises an air source manufacturing device (141), an air passage control device (142), a low-temperature conversion device (143) and a device connecting piece (144) which are sequentially connected, an air outlet end of the device connecting piece (144) and the vacuum unit (13) are respectively communicated with the cryoablation catheter (2), the low-temperature conversion device (143) comprises a Dewar flask (1431) and a heat exchanger (1432), the air source manufacturing device (141) is arranged in the Dewar flask (1431), an air outlet end of the air source manufacturing device (141) is communicated with an air inlet end of the air passage control device (142), and the air source manufacturing device (141) comprises a coolant storage tank (1411), and a delivery unit (14), The control unit (12) comprises a pressure relief valve (1413) communicated with the coolant storage tank (1411), a coolant supplement joint (1412) communicated with the coolant storage tank (1411) and a heating device (1414) arranged in the coolant storage tank (1411), the vacuum unit (13) and the gas circuit control device (142) are electrically connected with the control unit (12) respectively, and the heating device (1414) and the PID controller (123) are electrically connected.
2. The PID-controlled, self-pressurizing cryoablation system of claim 1 wherein: the coolant storage tank (1411) is a vacuum insulated storage tank.
3. The PID-controlled, self-pressurizing cryoablation system of claim 1 wherein: the gas source manufacturing device (141) comprises a liquid level measuring device (1415), the liquid level measuring device (1415) is electrically connected with the control unit (12), and the liquid level measuring device (1415) is arranged inside the coolant storage tank (1411).
4. The PID-controlled, self-pressurizing cryoablation system of claim 3 wherein: the gas source manufacturing device (141) comprises a pressure sensor (1416), the pressure sensor (1416) is communicated with the coolant storage tank (1411), the control unit (12) further comprises an industrial personal computer assembly (121) and a display (122) electrically connected with the industrial personal computer assembly (121), the PID controller (123) is electrically connected with the industrial personal computer assembly (121), the pressure sensor (1416) is electrically connected with the PID controller (123), and when the pressure in the coolant storage tank (1411) is not in an application range, the working frequency of the heating device (1414) is controlled through the PID controller (123), so that the pressure in the coolant storage tank (1411) reaches the application range.
5. The PID-controlled, self-pressurizing cryoablation system of claim 3 wherein: the gas source manufacturing device (141) comprises a silencer (1417), the pressure relief valve (1413) is communicated with the silencer (1417), when the internal pressure of the coolant storage tank (1411) exceeds a limit pressure, the pressure relief valve (1413) is opened, gas is discharged through the pressure relief valve (1413), and noise is reduced through the silencer (1417).
6. The PID-controlled, self-pressurizing cryoablation system of claim 3 wherein: the gas source manufacturing device (141) comprises a coolant supplement connector (1412) and an exhaust valve (1418), the coolant supplement connector (1412) and the exhaust valve (1418) are electrically connected with the control unit (12), and the coolant supplement connector (1412) and the exhaust valve (1418) are in an interlocking structure.
7. The PID-controlled, self-pressurizing cryoablation system of claim 1 wherein: the gas circuit control device (142) comprises a freezing solenoid valve (1422) and a rewarming solenoid valve (1423), the freezing solenoid valve (1422) is communicated with the air inlet end of the heat exchanger (1432), and the air outlet end of the heat exchanger (1432) and the rewarming solenoid valve (1423) are respectively communicated with the inlet of the equipment connecting piece (144).
8. The PID-controlled, self-pressurizing cryoablation system of claim 1 wherein: the coolant storage tank (1411) is a sealed device.
CN201822058418.4U 2018-12-10 2018-12-10 PID (proportion integration differentiation) controlled self-pressurization cryoablation system Withdrawn - After Issue CN209808515U (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109431594A (en) * 2018-12-10 2019-03-08 康沣生物科技(上海)有限公司 A kind of pressurization Cryoablation system certainly of PID control
CN116172687A (en) * 2023-01-04 2023-05-30 上海交通大学 Negative pressure regulation and control type cryotherapy system and control method

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109431594A (en) * 2018-12-10 2019-03-08 康沣生物科技(上海)有限公司 A kind of pressurization Cryoablation system certainly of PID control
CN109431594B (en) * 2018-12-10 2023-11-24 康沣生物科技(上海)股份有限公司 PID-controlled self-pressurizing cryoablation system
CN116172687A (en) * 2023-01-04 2023-05-30 上海交通大学 Negative pressure regulation and control type cryotherapy system and control method
CN116172687B (en) * 2023-01-04 2024-04-23 上海交通大学 Negative pressure regulation and control type cryotherapy system and control method

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