CN209771499U - Plasma sample extracting solution filtering device for high-stability metabonomics research - Google Patents

Abstract

The utility model discloses a plasma sample extract filter equipment of metabonomics research that stability is high, including funnel, centrifuging tube, rack and funnel frame, the standing groove has been seted up at the top of rack, the internal surface of standing groove and the surface sliding connection of centrifuging tube, and connecting groove has been seted up on the surface of funnel frame, and connecting groove's internal surface and the surface sliding connection of funnel, the top fixedly connected with locating plate of funnel frame, the guide hole has been seted up on the surface of locating plate, the utility model relates to a medical science assists articles for use technical field. This plasma sample extract filter equipment of metabonomics research that stability is high carries out multiple multistage spacing to the funnel, very big reduction the funnel because rock suddenly in-process that leads to the device to appear damaging, the risk that blood spatters appears, reduce the in-process that the device used simultaneously and the area of contact of outside air, reduce the pollution risk, effectively guaranteed the quality of blood.

Description

Plasma sample extracting solution filtering device for high-stability metabonomics research

Technical Field

The utility model relates to a medical science auxiliary articles for use technical field specifically is a plasma sample extract filter equipment of metabonomics research that stability is high.

Background

Metabonomics is a research mode for carrying out quantitative analysis on all metabolites in an organism and searching the relative relation between the metabolites and physiological and pathological changes by imitating the research ideas of genomics and proteomics, is a component of system biology, mostly has small molecular substances with the relative molecular mass of less than 1000, is a basic method for metabonomics research by combining advanced analysis and detection technology with calculation and analysis methods such as pattern recognition, expert systems and the like, and blood is an important raw material in the research.

In order to meet the requirement of research, the plasma sample needs to be extracted and filtered, and a plasma sample extracting solution filtering device for metabonomics research, which is described in patent No. 201820611159.0, can be seen, in order to ensure that when the funnel is used for filtering, filtrate overflows due to the over-high speed, the speed is slow, the time is wasted, meanwhile, the device has the problems of poor stability and complex operation during filtration, the overflow prevention is realized by additionally arranging the upper retaining ring to be matched with the filter screen body, the stable positioning is realized by being matched with the funnel stand and the placing rack, the device does not perform strong limiting on the funnel and the centrifugal tube, in the using process, the condition of blood sputtering can easily occur due to the large shaking caused by the error of working personnel, the using quality is affected, meanwhile, the mode of heightening the retainer ring is adopted, so that the contact time of the blood and the outside air is longer, and the blood quality is seriously influenced.

SUMMERY OF THE UTILITY MODEL

The utility model provides a not enough to prior art, the utility model provides a plasma sample extract filter equipment of metabonomics research that stability is high has solved current device and has not carried out brute force spacingly to the funnel, at the in-process that uses, because staff's error, great rocking appears, the condition that blood spattered will appear very easily, influences the use quality, and the mode that adopts the increase retaining ring simultaneously makes blood longer with outside air contact time, seriously influences the problem of blood quality.

In order to achieve the above purpose, the utility model discloses a following technical scheme realizes: a plasma sample extract filtering device for high-stability metabonomics research comprises a funnel, a centrifuge tube, a placing rack and a funnel rack, the top of the placing rack is provided with a placing groove, the inner surface of the placing groove is connected with the outer surface of the centrifugal tube in a sliding way, the surface of the funnel stand is provided with a connecting groove, the inner surface of the connecting groove is connected with the outer surface of the funnel in a sliding way, the top of the funnel stand is fixedly connected with a positioning plate, and the surface of the positioning plate is provided with a guide hole, the inner surface of the guide hole is connected with the outer surface of the funnel in a sliding way, the inner surface of the connecting groove is fixedly connected with an elastic stabilizing block, the inner surface of the elastic stabilizing block is tightly contacted with the outer surface of the funnel, the bottom of the funnel stand is fixedly connected with a connecting inserting block, the left side and the right side of the top of the placing frame are fixedly connected with connecting slot plates, and the outer surfaces of the connecting plug blocks are connected with the inner surfaces of the connecting slot plates in a clamping mode.

Preferably, the top threaded connection of funnel surface has the isolation lid, the feed inlet has been seted up at the top of isolation lid, the internal surface fixedly connected with coarse filtration net of feed inlet, and the internal surface of funnel from last to down sliding connection have primary filter net and smart filter net in proper order.

Preferably, the inner surface of the connecting groove is fixedly connected with a soft pad, and the inner surface of the soft pad is in close contact with the outer surface of the centrifugal tube.

Preferably, the bottom of the outer surface of the funnel is slidably connected with the inner surface of the centrifuge tube.

Preferably, the positioning plate and the isolating cover are both made of medical plastic materials.

Preferably, the bottom of the funnel stand is fixedly connected with an isolation pad, and the bottom of the isolation pad is in close contact with the top of the centrifuge tube.

Advantageous effects

The utility model provides a plasma sample extract filter equipment of metabonomics research that stability is high. Compared with the prior art, the method has the following beneficial effects:

(1) The plasma sample extract filtering device for metabonomics research with high stability is characterized in that a positioning plate is fixedly connected to the top of a funnel frame, a guide hole is formed in the surface of the positioning plate, the inner surface of the guide hole is in sliding connection with the outer surface of a funnel, an elastic stabilizing block is fixedly connected to the inner surface of a connecting groove, the inner surface of the elastic stabilizing block is in close contact with the outer surface of the funnel, a connecting plug block is fixedly connected to the bottom of the funnel frame, connecting socket plates are fixedly connected to the left side and the right side of the top of the placing frame, the outer surface of the connecting plug block is connected with the inner surface of the connecting socket plate in a clamping manner, and multiple multi-section limiting is carried out on the funnel by matching the positioning plate, the guide hole, the elastic stabilizing block, the connecting plug block and the connecting socket plates, so that the risk of damage, the problem of current device carry out brute force spacing to the funnel not, at the in-process of using, because staff's error appears great rocking, the condition that will appear blood sputtering very easily, influences the use quality is solved.

(2) This plasma sample extract filter equipment of metabonomics research that stability is high, there is the isolation lid through the top threaded connection at the funnel surface, the feed inlet has been seted up at the top of isolation lid, the internal surface fixedly connected with coarse filtration net of feed inlet, the internal surface of funnel has primary filter net and smart filter screen from last to sliding connection down in proper order, the lid is kept apart in the cooperation, the feed inlet, the coarse filtration net, the setting of primary filter net and smart filter screen, the in-process and the external air's area of contact of reducing means using, reduce the pollution risk, effectively guaranteed the quality of blood, it makes blood longer with external air contact time to have solved the mode that current device adopted the increase retaining ring, seriously influence the problem of blood quality.

Drawings

Fig. 1 is a schematic view of the internal structure of the present invention;

Fig. 2 is a cross-sectional view of the funnel structure of the present invention;

Fig. 3 is a partially enlarged view of a portion a in fig. 2 according to the present invention.

In the figure: 1-funnel, 2-centrifuging tube, 3-rack, 4-funnel frame, 5-standing groove, 6-connecting groove, 7-locating plate, 8-guide hole, 9-elastic stable piece, 10-connecting inserted block, 11-connecting slot board, 12-isolation cover, 13-feed inlet, 14-coarse filter screen, 15-prefilter screen, 16-fine filter screen, 17-cushion, 18-isolation pad.

Detailed Description

the technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.

Referring to fig. 1-3, the present invention provides a technical solution: a plasma sample extracting solution filtering device for high-stability metabonomics research comprises a funnel 1, a centrifugal tube 2, a placing rack 3 and a funnel frame 4, wherein the bottom of the outer surface of the funnel 1 is in sliding connection with the inner surface of the centrifugal tube 2, an isolating pad 18 is fixedly connected to the bottom of the funnel frame 4, the bottom of the isolating pad 18 is in close contact with the top of the centrifugal tube 2, the isolating pad 18 has elasticity, the contact between outside air and blood inside the centrifugal tube 2 can be effectively reduced, an isolating cover 12 is in threaded connection with the top of the outer surface of the funnel 1, a positioning plate 7 and the isolating cover 12 are both made of medical plastic materials, a feeding hole 13 is formed in the top of the isolating cover 12, a coarse filtering net 14 is fixedly connected to the inner surface of the feeding hole 13, a primary filtering net 15 and a fine filtering net 16 are sequentially in sliding connection with the inner surface of the funnel 1 from, the device is matched with the arrangement of an isolation cover 12, a feed inlet 13, a coarse filter screen 14, a primary filter screen 15 and a fine filter screen 16, the contact area of the device with the outside air in the using process is reduced, the pollution risk is reduced, the quality of blood is effectively ensured, the problem that the contact time of the blood and the outside air is long due to the fact that the existing device adopts a mode of heightening a retainer ring, and the blood quality is seriously affected is solved, the top of a placing frame 3 is provided with a placing groove 5, the inner surface of the placing groove 5 is in sliding connection with the outer surface of a centrifuge tube 2, the inner surface of a connecting groove 6 is fixedly connected with a cushion 17, the inner surface of the cushion 17 is in close contact with the outer surface of the centrifuge tube 2, the surface of a funnel frame 4 is provided with a connecting groove 6, the inner surface of the connecting groove 6 is in, the inner surface of the guide hole 8 is in sliding connection with the outer surface of the funnel 1, the inner surface of the connecting groove 6 is fixedly connected with an elastic stabilizing block 9, the inner surface of the elastic stabilizing block 9 is in tight contact with the outer surface of the funnel 1, the bottom of the funnel frame 4 is fixedly connected with a connecting insertion block 10, the left side and the right side of the top of the placing frame 3 are both fixedly connected with a connecting insertion groove plate 11, the outer surface of the connecting insertion block 10 is in clamping connection with the inner surface of the connecting insertion groove plate 11, the positioning plate 7, the guide hole 8, the elastic stabilizing block 9, the connecting insertion block 10 and the connecting insertion groove plate 11 are matched, multiple limiting and multi-section are carried out on the funnel 1, the risks that the device is damaged due to sudden shaking and blood sputtering in the using process of the funnel 1 are greatly reduced, the problems that the existing device does not carry out powerful limiting on the, the blood sputtering condition can easily occur due to the large shaking, and the problem of influencing the use quality is solved.

During the use, put into connecting grooves 6 with centrifuging tube 2 earlier, then make and connect plug 10 and insert in connecting socket board 11, make isolation pad 18 in close contact with centrifuging tube 2, later open isolation lid 12, put into funnel 1 with smart filter screen 16, primary filter screen 15 in proper order, then cover on funnel 1 after being stained with filter paper and being wet, twist isolation lid 12 again, insert funnel 1 along guide hole 8, rotate funnel 1 make point mouth department laminating centrifuging tube 2 inner wall can.

It is noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus.

Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (6)

1. The utility model provides a plasma sample extract filter equipment that metabonomics research that stability is high, includes funnel (1), centrifuging tube (2), rack (3) and funnel frame (4), standing groove (5) have been seted up at the top of rack (3), the internal surface of standing groove (5) and the surface sliding connection of centrifuging tube (2), connecting groove (6) have been seted up on the surface of funnel frame (4), and the internal surface of connecting groove (6) and the surface sliding connection of funnel (1), its characterized in that: the top fixedly connected with locating plate (7) of funnel frame (4), and guide hole (8) have been seted up on the surface of locating plate (7), the internal surface of guide hole (8) and the surface sliding connection of funnel (1), the internal surface fixed connection of coupling groove (6) has elastic stabilization piece (9), and the internal surface of elastic stabilization piece (9) and the surface in close contact with of funnel (1), the bottom fixedly connected with of funnel frame (4) connects inserted block (10), the equal fixedly connected with of the left and right sides at rack (3) top connects slotted plate (11), and connects the surface of inserted block (10) and the internal surface joint of connecting slotted plate (11).

2. The device for filtering plasma sample extract in high stability metabonomics research according to claim 1, wherein: the top threaded connection of funnel (1) surface has isolation lid (12), feed inlet (13) have been seted up at the top of isolation lid (12), the internal surface fixedly connected with coarse filtration net (14) of feed inlet (13), and the internal surface of funnel (1) from last to having under to in proper order sliding connection have primary filter screen (15) and smart filter screen (16).

3. The device for filtering plasma sample extract in high stability metabonomics research according to claim 1, wherein: the inner surface fixed connection of connecting groove (6) has cushion (17), and the internal surface of cushion (17) and the surface in close contact with of centrifuging tube (2).

4. the device for filtering plasma sample extract in high stability metabonomics research according to claim 1, wherein: the bottom of the outer surface of the funnel (1) is in sliding connection with the inner surface of the centrifugal tube (2).

5. The device for filtering plasma sample extract in high stability metabonomics research according to claim 2, wherein: the positioning plate (7) and the isolation cover (12) are both made of medical plastic materials.

6. The device for filtering plasma sample extract in high stability metabonomics research according to claim 1, wherein: the bottom of the funnel stand (4) is fixedly connected with an isolation pad (18), and the bottom of the isolation pad (18) is in close contact with the top of the centrifugal tube (2).