CN209722106U - Full automatic microorganism identification and Analysis of Drug Susceptibility system - Google Patents

Abstract

The utility model discloses a kind of identification of full automatic microorganism and Analysis of Drug Susceptibility systems, including complete machine shell, and sample-adding unit, specimen discerning recording unit, support plate unit, hatch unit, detection unit and board buanch unit are provided in the inner cavity of complete machine shell；Sample-adding unit is automatically performed handling pipette tips, gun body imbibition and board sample-adding；Specimen discerning recording unit is located at sample-adding unit side, is scanned record and automatic selection to the specimen bottle for being loaded with sample；Support plate unit is located at the other side of sample-adding unit, for loading and scanning record board；The board that hatch unit completes sample-adding incubates；Detection unit carries out identification to the board after incubation and susceptibility detects；Board buanch unit is transferred to sample-adding unit by support plate unit as the combining mechanism between support plate unit, sample-adding unit and hatch unit, by board, then is pushed in hatch unit by the transfer of sample-adding unit.The utility model advantage is that simple to operate, sample throughput is big, high degree of automation.

Description

Full automatic microorganism identification and Analysis of Drug Susceptibility system

Technical field

The utility model relates to microorganism detection fields, more particularly, to a kind of identification of full automatic microorganism and Analysis of Drug Susceptibility System.

Background technique

Antimicrobial is clinically most common drug, treats bacterium infection and bacterial infection is curative for effect, is vast Doctor is widely applied.However, abuse of antibiotics phenomenon is very universal in recent years, this not only reduces curative effect, but also the poison of susceptibility Side reaction is big, adds block bacterial drug resistance, loses treatment and rescue opportunity, endangers to the health of patient with life zone.By The environmental requirements such as temperature height, humidity difference required for various bacterial micro-organism cultures are not quite similar, raw carrying out molecule It generally requires manually to found required environment when object and Bacteria Culture, once the bacterium and microbe species that need to cultivate are more, then It is easy to that medical worker's workload is caused to increase and is likely to cause operation error, bring big inconvenience to medical worker.

With the continuous development of science and technology, requirement of the people to medical treatment detection device the degree of automation is also higher and higher； And existing microbial identification and Analysis of Drug Susceptibility instrument usually only incubate and analytic function, the degree of automation is low, needs manually to exist It is loaded outside analyzer and carries out board transfer, then placed into instrument and incubated and analyzed, and single treatment sample Measure small, manual operation content is more, and unpredictalbe risk is big, increases the workload of operator；This instrument is far from It is able to satisfy growing microorganism detection demand.It is badly in need of a high degree of automation, easy to operate, processing mark on the market at present The big microbial identification of this amount and Analysis of Drug Susceptibility equipment.

Summary of the invention

The utility model aim is to provide the full automatic microorganism identification and medicine that one kind is easy to operate, sample throughput is big Quick analysis system.

To achieve the above object, the utility model can take following technical proposals:

Full automatic microorganism identification described in the utility model and Analysis of Drug Susceptibility system, including complete machine shell, described whole Sample-adding unit, specimen discerning recording unit, support plate unit, hatch unit, detection unit and plate are provided in the inner cavity of casing body Card buanch unit；

The sample-adding unit is automatically performed handling pipette tips, gun body imbibition and board sample-adding；

The specimen discerning recording unit is located at the sample-adding unit side, is scanned to the specimen bottle for being loaded with sample Record and automatic selection；

The support plate unit is located at the other side of the sample-adding unit, for loading and scanning record board；

The hatch unit, the board completed to sample-adding incubate；

The detection unit carries out identification to the board after incubation and susceptibility detects；

The board buanch unit is as the combining mechanism between support plate unit, sample-adding unit and hatch unit, by board Sample-adding unit is transferred to by support plate unit, then is pushed in hatch unit by the transfer of sample-adding unit.

The sample-adding unit includes being installed on the intracorporal braced frame of complete machine shell, and longitudinal direction is fixedly arranged on the support Backboard on rear side of frame between two columns；It is horizontally disposed with to have on the trailing flank of the backboard and be synchronized by the motor-driven X-axis of X-axis Tape handler is fixed with the cantilevered leg extended horizontally forward on the synchronous belt of the X-axis synchronous belt drive mechanism, described outstanding Being horizontally disposed on semi-girder has the Y-axis synchronous belt drive mechanism driven by y-axis motor, the synchronization of the Y-axis synchronous belt drive mechanism The sample arm for being fixed with and extending vertically downward is taken, is vertically arranged on the sample arm synchronous by the motor-driven Z axis of Z axis Tape handler is fixed with the sample loading gun of liquid sucting port vertically downward on the synchronous belt of the Z axis synchronous belt drive mechanism；Described Microwell plate bearing device and pipette tips handler are provided with below the motion profile of sample arm.

The sample loading gun includes the imbibition pump motor being fixed on the synchronous belt of the Z axis synchronous belt drive mechanism, described The working shaft of imbibition pump motor vertically downward, the drive lead screw of synchronous rotation is fixed in its lower end by shaft coupling, described The feed screw nut moved above and below along its length is provided on drive lead screw, it is downward in the downward vertical of the drive lead screw It is provided with the piston type suction pumps rifle being fixedly connected with the shell of the imbibition pump motor, the upper end of the piston type suction pumps rifle is living Stopper rod is fixedly connected with the feed screw nut, and active card is equipped with disposable in the pipette tips carrying case on the liquid sucting port of lower end Imbibition pipette tips；

The microwell plate bearing device includes support pedestal, is vertically equipped on the support pedestal and drives electricity by substrate The live spindle that machine drives is fixedly connected at the upper end of the live spindle and horizontally disposed support substrate bottom surface center；It is described Two sets of microwell plate support components supports are installed on support substrate side by side, microwell plate support components support described in every set includes one group of microwell plate Bracket and one group of plate lid fix frame, and the height that the plate lid fixes frame is higher than the height of the micropore board bracket, two sets of microwell plates Micropore board bracket and plate lid in support components support fix frame and are laid staggeredly；

The pipette tips handler includes that the pipette tips being set on front side of the microwell plate bearing device discard storehouse, in the rifle Being provided in discarded storehouse from the complete machine shell leading flank extraction or the discarded pipette tips storage compartment that is put into, discards storehouse in pipette tips Roof on offer pipette tips and fall mouth, fallen above mouth in the pipette tips and be provided with support of the upper surface with pipette tips carrying case Table offers on the support desk and falls the corresponding Pear-Shaped pipette tips of mouth with the pipette tips and slough mouth.

The specimen discerning recording unit includes the specimen support seat being set to below the sample arm motion profile, in institute It states and is vertically equipped on specimen support seat by the motor-driven sample tray rotary shaft of identification record unit, the sample tray rotation The upper end level of shaft is fixed with specimen bottle pallet connecting plate, and activity is placed with annular support on the specimen bottle pallet connecting plate Disk is distributed along the circumference with several card slots for inserting specimen bottle on the annular pallet, on the inside and outside side wall of the specimen bottle point It is not pasted with product export bar code and patient information bar code；It is solid respectively on the specimen support seat of the annular pallet medial and lateral Equipped with the product export bar code and the corresponding barcode scanner of patient information barcode position on same specimen bottle；Institute The lower surface for stating specimen bottle pallet connecting plate is fixed with annular code-disc, the specimen support seat positioned at the annular code-disc side On be provided with code-disc origin position sensor and code-disc indexing position sensor.

The support plate unit includes being set to microwell plate bearing device side firm banking, on the fixed base Board relieving mechanism is fixed with by spaced a pair of vertical supporting plate；

The board relieving mechanism includes the bottom cover being horizontally located on the two vertical supporting plates, is offered on the bottom cover Board liberation port, by the guide pin active card that is fixed on bottom cover equipped with straight-flanked ring knot at the upper edge of the board liberation port The opening-closing plate of structure；The opening-closing plate is docked by the U-shaped thin plate that a pair moves toward one another, and is led at the docking of the two U-shaped thin plates It crosses rotary sleeve to be linked together, the bottom wall thin plate opposite side of two U-shaped thin plates is provided with one group of symmetrical claw, wherein a U The return spring that outer end is connected with the bottom cover is provided on shape thin plate, the draw direction and the U-shaped of the return spring are thin The folding direction of plate is consistent；Board release motor, the work of the board release motor are installed on the lower surface of the bottom cover Make coaxially to be fixed with board release lead screw on axis, the axis direction of the board release lead screw and the folding direction of two U-shaped thin plates Unanimously, it is provided with the nut seat for driving the folding of two U-shaped thin plates on board release lead screw, is spaced on board release motor It is provided with a pair of for monitoring the distance position sensor of the nut seat movement travel；It is buckled in the top of the two U-shaped thin plates Conjunction has the connection pedestal being fixedly connected with the bottom cover, offers on the connection pedestal and the consistent board of board liberation port It is logical to offer U-shaped corresponding with the information bar code position on microwell plate at a side of board whereabouts mouth for whereabouts mouth Slot；

Board storehouse mechanism is provided on the card relieving mechanism, board storehouse mechanism includes being vertically located in institute The block column of board whereabouts mouth four corners is stated, the upper end of the block column is linked together by connecting top plate, formation and institute Microwell plate compatible board storehouse storehouse is stated, magnetic attracting door with handles is hinged in the side in board storehouse storehouse, with Hall sensor is installed on the attracted block column of the magnetic attracting door.

The hatch unit includes the incubator that the sample-adding unit side is arranged in, and is provided with and incubates in the incubator Pedestal is educated, the upper surface for being incubated for pedestal is horizontally disposed thin-wall bearing, inner ring and the incubation pedestal phase of the thin-wall bearing Be connected, be installed on outer ring by being incubated for motor-driven driven pulley, the upper surface of the driven pulley with coaxially lay Level is incubated for disk and is fixedly connected with, and horizontal be incubated for is distributed along the circumference with the incubation pylon of several groups opening outwardly on disk, described to incubate It educates longitudinal gap in pylon and is arranged with several layers microwell plate card slot, every group of incubation pylon is fixed by a pin to horizontal incubation disk Upper surface；

It is offered on the side wall of the incubator into plate mouth and plate outlet, is opened up by longitudinal gap if described into plate mouth It does into plate door opening and constitutes, it is described to be corresponded into plate door opening and the microwell plate card slot, into passing through automatic rebounding on plate door opening Hinge, which is hinged with, to push；The plate outlet is connected to the sealing of the front side wall of the complete machine shell, and the size of plate outlet is incubated with one group The outer openings size for educating pylon is adapted, and is hinged with incubator storehouse on complete machine shell front side wall corresponding with the plate outlet Door；It is provided with the heating blower with heater strip on the roof of the incubator, is provided with temperature sensor in incubator, is located at Incubation information display screen is provided on complete machine shell front side wall below the incubator door.

It is provided with speed changer on the incubation pedestal, the speed changer is fixed on incubation base lower surface by fixed plate On, the output end of speed changer extends vertically up to be incubated for above pedestal, is provided with driving pulley, and the driving pulley is logical It crosses transmission belt and the driven pulley is sequentially connected, the input terminal of speed changer is passed by synchronous drive mechanism and the incubation motor Dynamic connection；Several incubation information instructions are provided in the plate outlet opening's edge corresponding with the incubator door enabling side Lamp, the microwell plate card slot incubated on incubation pylon described in information indicator light and one group correspond.

The detection unit includes the detection pedestal being set at the incubation pylon medial center, in the detection pedestal On be vertically arranged with the first guide rail, sliding is provided with by the information collection of the first power mechanism driving lifting on first guide rail Mechanism detects and is provided with the balance weight mechanism for preventing the information collection mechanism from falling on pedestal；

The information collection mechanism includes the horizontal lifting frame being slidably arranged on first guide rail, the horizontal lifting Frame inner close fitting long side side wall is horizontally disposed the second guide rail, and sliding is provided on second guide rail is driven by the second power mechanism Sliding block, the side level of the sliding block is fixed with pallet link block, is connected in the pallet link block far from the side of sliding block Have a detection pallet, the pallet inlet and outlet that the detection pallet is opened up from the horizontal lifting frame short side side wall across；Described It is provided with optical fiber fixed block at the lower opening's edge of pallet inlet and outlet, the bottom of the horizontal lifting frame is provided with LED light, it is described The light that LED light issues is radiated on the detection pallet by optical fiber through the optical fiber fixed block, on the top of the horizontal lifting frame Portion is covered with photoelectric signal transforming module.

The balance weight mechanism includes longitudinal in the door shape frame on the detection pedestal, and first guide rail and information are adopted Collecting mechanism is located on the inside of the door shape frame, is vertically arranged with third guide rail on the detection pedestal at door shape frame rear, The hanging axis being equipped with above the photoelectric signal transforming module on the horizontal lifting frame, the hanging axis is along the door word The width direction of shape frame is horizontally disposed, and the fixed pulley and cunning that the cable wire on hanging axis bypasses door shape frame roof are fixed in one end The dynamic clump weight being arranged on the third guide rail is fixedly connected with.

The board buanch unit includes the longitudinal substrate that fitting is fixed on the backboard leading flank, in longitudinal base Being horizontally disposed on the leading flank of plate has the lateral transmission belt driven by horizontal drive motor, below the lateral transmission belt Be arranged at intervals with several arm Board position sensors on longitudinal substrate along its length, the conveying end of lateral transmission belt with it is described Being adapted into plate mouth for incubator corresponds to, and is installed with vertical arms plate on lateral transmission belt；

One end of the vertical arms plate is provided with vertical drive motor, the working shaft end of the vertical drive motor is logical Cross the synchronous rotation lead screw that shaft coupling is connected on front side of vertical arms plate, the axial direction for rotating synchronously lead screw and the longitudinal direction Arm plate length direction is consistent, is provided with the feed screw nut slided above and below on rotating synchronously lead screw, is provided on vertical arms plate With the synchronous rotation consistent altitude location plate of lead screw length direction, microwell plate transfer support bracket is provided on the feed screw nut With nut location sensor compatible with the altitude location plate；

The microwell plate transfer support bracket includes being fixed on the board transfer extended horizontally forward on the feed screw nut to hang Semi-girder, in board transfer cantilevered leg it is horizontal be fixed with the board transfer carriage to match into plate door opening, in institute It states and is provided with bracket sensors in place on the side of board transfer carriage.

The utility model advantage is that simple to operate, sample throughput is big, high degree of automation.It is whole by being set to Sample-adding unit, specimen discerning recording unit, support plate unit, hatch unit, detection unit and board transfer in casing intracoelomic cavity Unit, come the scanning record of sample before completing to be loaded and it is automatic choose, disposable imbibition pipette tips of automatic mounting before sample loading gun imbibition, Board after the completion of the removal, sample-adding of disposable imbibition pipette tips after the completion of the automatic support plate of board, sample loading gun imbibition sample-adding, sample-adding Automatic transfer, board are incubated for and carry out to board after the completion of incubation a series of actions of identification and susceptibility detection；Disposably upper machine It is of large quantities, meet ever-increasing detection demand, agree with the growth requirement of susceptibility industry, realizes sample-adding, transfer, incubates, interpretation Fully enclosed automatic operation, improves working efficiency, reduces manual intervention, is truly realized 24 hours unattended targets, has Effect avoids the risk as brought by manual intervention；In addition, whole use modularized design, modules can be dismantled individually, after Phase safeguards and maintains very convenient.

Detailed description of the invention

Fig. 1 is the structural schematic diagram of the utility model.

Fig. 2 is the top view (concealing complete machine shell) of Fig. 1.

Fig. 3, Fig. 4 are the schematic diagram of internal structures that Fig. 1 conceals machine shell and incubator.

Fig. 5, Fig. 6 are the structural schematic diagrams that unit is loaded in Fig. 1.

Fig. 7 is the enlarged drawing that sample loading gun in unit is loaded in Fig. 1.

Fig. 8 is the structural schematic diagram of microwell plate bearing device in Fig. 1.

Fig. 9 is the perspective view of Fig. 8.

Figure 10 is the structural schematic diagram of specimen discerning recording unit in Fig. 1.

Figure 11 is the perspective view of Figure 10.

Figure 12 is the enlarged drawing of specimen bottle in Figure 10.

Figure 13 is the decomposition texture schematic diagram of support plate unit in Fig. 1.

Figure 14 is the enlarged drawing of board relieving mechanism in Figure 13.

Figure 15 is the enlarged drawing of microwell plate in Figure 13.

Figure 16 is the structural schematic diagram of hatch unit in Fig. 1.

Figure 17, Figure 18 are the structural schematic diagrams that incubator is concealed in Figure 16.

Figure 19 is the structural schematic diagram of detection unit in Fig. 1.

Figure 20 is the perspective view of Figure 19.

Figure 21 is the structural schematic diagram (concealing the second power mechanism) of information collection mechanism in Figure 19.

Figure 22, Figure 23 are the structural schematic diagrams of board buanch unit in Fig. 1.

Figure 24 is the enlarged drawing (concealing microwell plate) of microwell plate transfer support bracket in Figure 22.

Specific embodiment

As shown in Figs 1-4, full automatic microorganism identification described in the utility model and Analysis of Drug Susceptibility system, including complete machine shell Body 1, be provided in the inner cavity of complete machine shell 1 sample-adding unit 2, specimen discerning recording unit 3, support plate unit 4, hatch unit 5, Detection unit 6 and board buanch unit 7；It is loaded unit 2, specimen discerning recording unit 3, support plate unit 4, hatch unit 5, detection Unit 6 and board buanch unit 7 are controlled by PLC controller.

Sample-adding unit 2 can be automatically performed handling pipette tips, gun body imbibition and board sample-adding；As shown in Figure 5,6, it is loaded unit 2 include the braced frames 201 that are installed in complete machine shell 1, braced frame 201 by be fixed in 1 inner bottom wall of complete machine shell four A longitudinal direction column and the attachment beam for being fixed on longitudinal the upper end of the column are constituted, longitudinal between two columns of 201 rear side of braced frame It is installed with backboard 202；Being horizontally disposed on the trailing flank of backboard 202 has the X-axis toothed belt transmission machine driven by X-axis motor 203 Structure 204, be fixed on the synchronous belt of X-axis synchronous belt drive mechanism 204 bypass and extend horizontally forward from above backboard 202 it is outstanding Semi-girder 205, being horizontally disposed in cantilevered leg 205 has the Y-axis synchronous belt drive mechanism 207 driven by y-axis motor 206, and Y-axis is synchronous It is fixed with the sample arm 208 extended vertically downward on the synchronous belt of tape handler 207, is vertically arranged on sample arm 208 The Z axis synchronous belt drive mechanism 210 driven by Z axis motor 209 is fixed with suction on the synchronous belt of Z axis synchronous belt drive mechanism 210 The sample loading gun of liquid mouth vertically downward is provided with microwell plate bearing device and pipette tips handling below the motion profile of sample arm 208 Device.

Cantilevered leg 205 is backhauled under the drive of X-axis synchronous belt drive mechanism 204 along the X-direction of braced frame 201 Dynamic, Y direction of the sample arm 208 under the drive of Y-axis synchronous belt drive mechanism 207 along braced frame 201 moves back and forth, sample-adding Z-direction of the rifle under the drive of Z axis synchronous belt drive mechanism 210 along braced frame 201 moves back and forth, to realize sample loading gun The movement of arbitrary orientation.

It is to guarantee that cantilevered leg 205 is stablized with X-axis synchronous belt drive mechanism 204 to move, is provided on backboard 202 and X-axis The consistent X-axis guide rail 211 of 204 length direction of synchronous belt drive mechanism, the length and X-axis synchronous belt drive mechanism of X-axis guide rail 211 204 length is adapted, and the X-axis slide block 212 that cantilevered leg 205 is installed in X-axis guide rail 211 with sliding is fixedly connected with, and is formed X-axis and is led Rail 211, which is stablized, play the guiding role to the movement of cantilevered leg 205 while fixing cantilevered leg 205；In addition, due to cantilevered leg 205 Extension elongation is longer, therefore to avoid 205 front end of cantilevered leg from dropping, the height of cantilevered leg 205 is arranged with braced frame 201 Connection depth of beam it is consistent, and level opens up supporting skid rail 213 on the attachment beam medial surface of the front side of braced frame 201, outstanding The front end of semi-girder 205 is provided with the support slipper 214 being slidably matched with supporting skid rail 213, is formed to the steady of 205 front end of cantilevered leg Fixed support.

It is to guarantee that sample arm 208 is stablized with Y-axis synchronous belt drive mechanism 207 to move, is provided in cantilevered leg 205 and Y The consistent Y-axis guide rail 215 of 207 length direction of axis synchronous belt drive mechanism, the length and Y-axis toothed belt transmission machine of Y-axis guide rail 215 The length of structure 207 is adapted, and the Y-axis sliding block 216 that sample arm 208 is installed in Y-axis guide rail 215 with sliding is fixedly connected with, and forms Y-axis Guide rail 215, which is stablized, play the guiding role to the movement of sample arm 208 while fixing sample arm 208.

It moves, is provided on sample arm 208 same with Z axis to guarantee that sample loading gun is stablized with Z axis synchronous belt drive mechanism 210 Walk the consistent Z axis guide rail 217 of 210 length direction of tape handler, the length and Z axis synchronous belt drive mechanism of Z axis guide rail 217 210 length is adapted, and the Z axis sliding block 218 that sample loading gun is installed in Z axis guide rail 217 with sliding is fixedly connected with, and forms Z axis guide rail 217 play the guiding role to the up and down motion of sample loading gun while stablizing fixing sample loading gun.

As shown in fig. 7, sample loading gun includes the imbibition pump motor being fixed on the synchronous belt of Z axis synchronous belt drive mechanism 210 219, the working shaft of imbibition pump motor 219 vertically downward, the driving wire of synchronous rotation is fixed in its lower end by shaft coupling Bar 220 is provided with the feed screw nut 221 moved above and below along its length on drive lead screw 220, under drive lead screw 220 Side is provided with the piston type suction pumps rifle 222(piston type suction pumps rifle being fixedly connected with the shell of imbibition pump motor 219 vertically downward 222 be existing common automatic liquid-feeding rifle, it can be achieved that accurately drawing sample and accurate sample-adding), piston type suction pumps rifle 222 it is upper End piston rod is fixedly connected with feed screw nut 221, drives drive lead screw 220 to rotate by imbibition pump motor 219, to make to be set to Feed screw nut 221 thereon moves up and down, and realizes that the piston rod of piston type suction pumps rifle 222 pushes and pulls up and down, completes imbibition or add Sample movement；Active card is equipped with disposable imbibition pipette tips 223 on the lower end liquid sucting port of piston type suction pumps rifle 222, disposable to inhale Liquid pipette tips 223 are detachable and interchangeable, effectively avoid cross contamination.

Microwell plate bearing device is typically secured in 1 inner bottom wall of complete machine shell at 201 center of braced frame；Such as Fig. 8,9 Shown, microwell plate bearing device includes support pedestal 224, is vertically equipped on support pedestal 224 by substrate driving motor 225 The live spindle 226 of drive, to keep structure more compact, substrate driving motor 225 is fixed on 224 lower surface of support pedestal, Live spindle 226 is driven by a set of synchronous belt drive mechanism；226 upper end of live spindle and horizontally disposed support substrate It is fixedly connected at 227 bottom center；To improve flexibility and stability when the work of microwell plate bearing device, close to support pedestal It is set with a pair of bearings (preferably zanjon bearing) in 224 live spindle 226, passes through spiral shell with the axle sleeve of bearing outer peripheral surface tight fit Bolt is fixedly mounted on support pedestal 224, is offered external screw thread in the live spindle 226 below bearing, is set gradually thereon There are locked spacer and locking nut.Two sets of microwell plate support components supports, every set microwell plate support are installed on support substrate 227 side by side Component includes one group of micropore board bracket 228 and one group of plate lid fixes frame 229, and the height that plate lid fixes frame 229 is higher than microwell plate The height of bracket 228 facilitates and first the plate lid of microwell plate is fastened on higher plate lid fixing frame 229, then decorporates downwards micro- Orifice plate, and block and be placed on micropore board bracket 228；Micropore board bracket 228 and plate lid in two sets of microwell plate support components supports fix frame 229 are laid staggeredly, and making sample application zone, there are two station (can place two microwell plates), when the microwell plate on a station has been loaded Cheng Hou drives support substrate 227 to rotate 180 °, can carry out to the microwell plate on another station by substrate driving motor 225 Sample-adding, can effectively save loading time, improve working efficiency.In addition, being provided with sample-adding origin in the upper surface of support pedestal 224 Position sensor 230 and sample-adding indexing position sensor 231 are provided in the lower surface of support substrate 227 and are loaded origin position Set the compatible origin position baffle 232 of sensor 230, and indexing position compatible with sample-adding indexing position sensor 231 Baffle 233, by being loaded the cooperation of origin position sensor 230 and origin position baffle 232, and sample-adding indexing position sensing The cooperation of device 231 and indexing position baffle 233 identifies and records the position of microwell plate in real time, position memory is realized, thus square Just automatic sample.

As shown in Figure 3,4, pipette tips handler includes that the pipette tips being set on front side of microwell plate bearing device discard storehouse 234, Discarded pipette tips storage compartment 235(such as Fig. 1 for being provided with from the leading flank of complete machine shell 1 extracting or be put into is discarded in storehouse 234 in pipette tips It is shown), pipette tips are offered on the roof that pipette tips discard storehouse 234 and fall mouth 236, are fallen above mouth 236 and are provided in pipette tips Support desk 238 of the surface with pipette tips carrying case 237 is placed with multiple disposable imbibition pipette tips 223 in pipette tips carrying case 237, adds It is moved downward after a disposable imbibition pipette tips 223 in sample rifle alignment pipette tips carrying case 237, just completes disposable imbibition pipette tips 223 installation；It is offered on support desk 238 and falls the corresponding Pear-Shaped pipette tips of mouth 236 with pipette tips and slough mouth 239, it is convenient Used disposable imbibition pipette tips 223 are sloughed, the disposable imbibition pipette tips 223 after sloughing directly fall on discarded pipette tips and deposit It puts in bucket 235.

Sample loading gun will carry out imbibition operation after the installation for completing disposable imbibition pipette tips 223, therefore just needs are first right The multiple specimen bottles for being loaded with sample liquid are scanned record, just can choose automatically corresponding sample when drawing sample liquid later Bottle, specimen discerning recording unit is precisely in order to completing this operation and being arranged.

As shown in Figure 10,11, specimen discerning recording unit 3 includes the sample being set to below 208 motion profile of sample arm The side of pipette tips handler is particularly arranged in specimen support seat 301 by support base 301, as far as possible shortening sample loading gun Movement travel in imbibition；The sample driven by identification record unit motor 302 is vertically equipped on specimen support seat 301 Pallet rotary shaft 303, to keep structure more compact, identification record unit motor 302 is fixed on 301 lower surface of specimen support seat On, sample tray rotary shaft 303 is also driven by a set of synchronous belt drive mechanism, sample tray rotary shaft 303 Upper end level is fixed with specimen bottle pallet connecting plate 304, to guarantee stability when work, equally in sample tray rotary shaft External screw thread is set on 303 and screws axle sleeve, is disposed with locked spacer in the sample tray rotary shaft 303 of axle sleeve lower end And locking nut, avoid sample tray rotary shaft 303 after being used for a long time from loose or dislocation phenomenon occur.

Activity is placed with annular pallet 305 on specimen bottle pallet connecting plate 304, is distributed along the circumference on annular pallet 305 Several card slots 307 for inserting specimen bottle 306 are pasted with product on the inside and outside side wall of specimen bottle 306 as shown in figure 12 respectively Bar code 308 of dispatching from the factory and patient information bar code 309；It is installed with respectively on the specimen support seat 301 of annular 305 medial and lateral of pallet With the corresponding barcode scanner 310 of product export bar code 308 and 309 position of patient information bar code on same specimen bottle 306, Two barcode scanners 310 are simultaneously scanned same specimen bottle 306, and scanning speed is fast, and working efficiency greatly improves.

It is fixed with annular code-disc 311 in the lower surface of specimen bottle pallet connecting plate 304, positioned at annular 311 side of code-disc It is provided with code-disc origin position sensor 312 and code-disc indexing position sensor 313 on specimen support seat 301, passes through code-disc original Point position sensor 312 and code-disc indexing position sensor 313 come identify and in real time record specimen bottle 306 position, realization position Memory is set, to insert position without considering when placing specimen bottle 306, facilitates operator to randomly place, substantially reduces behaviour Make difficulty.

In the laggard andante card sample-adding of sample loading gun imbibition, it is also necessary to microwell plate (as shown in figure 15) be pushed to micropore first On plate bearing device, therefore support plate unit 4 is set to the side of microwell plate bearing device.

As shown in Figure 13,14, support plate unit 4 includes firm banking 401, by spaced on firm banking 401 The vertical supporting plate 402 of a pair is fixed with board relieving mechanism；For the ability that fixes for enhancing vertical supporting plate 402, the side of two vertical supporting plates 402 leads to The reinforcing gusset 403 being installed on firm banking 401 is crossed to be linked together.

Board relieving mechanism includes the bottom cover 404 being horizontally located on two vertical supporting plates 402, offers plate on bottom cover 404 Card liberation port 405, board liberation port 405 are the rectangular configuration similar with the structure of existing microwell plate 406, and size is slightly larger than The size of existing microwell plate 406 guarantees that microwell plate 406 can smoothly fall out of board liberation port；Board liberation port 405 it is upper The opening-closing plate of rectangle ring structure is housed at opening's edge by 407 active card of guide pin being fixed on bottom cover 404；407 edge of guide pin The equal portion of the opening's edge of board liberation port 405 several, opening-closing plate is docked by the U-shaped thin plate 408 that moves toward one another of a pair, two U-shapeds It is linked together at the docking of thin plate 408 by rotary sleeve 409, moves the U-shaped thin plate 408 of side, drive the U-shaped of the other side thin Plate 408 does opposite direction movement therewith, to realize folding function；It is offered on two U-shaped thin plates 408 suitable with 407 phase of guide pin The length direction of the strip-shaped hole 410 matched, strip-shaped hole 410 is consistent with the direction of motion of U-shaped thin plate 408, and 407 activity of guide pin clamps In strip-shaped hole 410, the guiding role to guide pin 407 is realized.

The integral structure that two U-shaped thin plates 408 are made of two sidewalls thin plate and a bottom wall thin plate, in two U-shaped thin plates 408 Bottom wall thin plate opposite side be provided with one group of symmetrical claw 411, for fixing microwell plate 406；A wherein U-shaped thin plate The return spring 412 that outer end is connected with the bottom cover 404, the draw direction and U-shaped thin plate of return spring 412 are provided on 408 408 folding direction is consistent, and the two U-shaped thin plates 408 for being guaranteed at opening state fold under the action of return spring 412；In It is installed with board release motor 413 on the lower surface of bottom cover 404, is coaxially fixed with plate on the working shaft of board release motor 413 Card release lead screw 414, the axis direction that board discharges lead screw 414 is consistent with the folding direction of two U-shaped thin plates 408, releases in board The nut seat 415 for being provided on lead screw 414 and driving the folding of two U-shaped thin plates 408 is put, is spaced setting on board release motor 413 Have a pair of for monitoring the distance position sensor 416 of 415 movement travel of nut seat；The U-shaped thin plate of nut seat 415 and side 408 are connected, it is driven to complete opening and closing movement, and spaced two distance position sensor 416 is for monitoring nut seat 415 Position, and the range of nut seat 415 is limited.

Fastening in the top of two U-shaped thin plates 408 has the connection pedestal 417 being fixedly connected with bottom cover 404, connects on pedestal 417 Offer with 405 consistent board whereabouts mouth 418 of board liberation port, offered at a side of board whereabouts mouth 418 with it is micro- The corresponding U-shaped through slot 420 in 419 position of information bar code on orifice plate 406, sweep mechanism for cooperating it external to will under The microwell plate 406 fallen is scanned, and carries out storage record to information.

Board storehouse mechanism is provided on board relieving mechanism, board storehouse mechanism includes being vertically located in board whereabouts The block column 421 of 418 four corners of mouth, the upper end of block column 421 are linked together by connecting top plate 422, formation and micropore 406 compatible board storehouse storehouse 423 of plate is hinged with handles 424 magnetic attracting door in the side in board storehouse storehouse 423 425, Hall sensor is installed on the block column 421 attracted with magnetic attracting door 425, when magnetic attracting door 425 is not complete When shutting entirely, Hall sensor can issue alarm signal, and magnetic attracting door 425 is prompted not shut；In addition, in magnetic attracting door It is vertically arranged with the raised line 426 for pushing up solid microwell plate 406 on 425 medial surface, raised line can be passed through when shutting magnetic attracting door 425 426, which will be located at the microwell plate 406 in board storehouse storehouse 423, pushes up admittedly, avoids its left and right movement in board storehouse storehouse 423.

The direct level of microwell plate 406 is stacked in board storehouse storehouse 423, and the foolproof function for adaptation microwell plate 406 is (i.e. micro- One jiao of orifice plate 406 is right angle, remaining triangle is arc chord angle, and usually for microwell plate 406 when forward direction is placed, the lower right corner is straight Angle), two block columns, 421 medial surface far from magnetic attracting door 425 is the arcuate structure to match with microwell plate 406；Meanwhile Crawl groove 427 manually is offered on 418 edge of board whereabouts mouth of 425 lower section of magnetic attracting door, when in the bottom Microwell plate 406 when mistake occurs, microwell plate 406 can be manually taken out by grabbing groove 427 manually；In addition, for convenience of clear The board quantity for observing stacked microwell plate 406, be arranged from bottom to top on the wherein lateral surface of a block column 421 There is board quantity identity 428 corresponding with microwell plate 406, interval one is micro- between two neighbouring board quantity identities 428 The thickness distance of orifice plate 406.

It after the completion of microwell plate 406 is loaded through sample-adding unit 2, will enter in hatch unit 5, the plate that sample-adding is completed Card is incubated.

As shown in figs. 16-18, hatch unit 5 includes the incubator 501 that sample-adding 2 side of unit is arranged in, in incubator 501 Inside be provided with and be incubated for pedestal 502, be incubated for pedestal 502 upper surface it is horizontally disposed have a thin-wall bearing 503, thin-wall bearing 503 it is interior Circle is fixedly connected with pedestal 502 is incubated for, and the driven pulley 505 driven by incubation motor 504, driven pulley are installed on outer ring 505 upper surface is fixedly connected with the horizontal disk 506 that is incubated for coaxially laid, and is distributed along the circumference with eight groups on level incubation disk 506 and is incubated Pylon 507 is educated, longitudinal gap in pylon 507 is incubated for and is arranged with eight layers of microwell plate card slot 508, total can disposably be put into 64 A microwell plate 406, substantially increases support plate amount.It is incubated for pylon 507 for convenience of picking and placing, every group of incubation pylon 507 passes through pin It is fixed on horizontal incubation 506 upper surface of disk, and handle 509 is set in the upper surface for being incubated for pylon 507.In addition, existing for convenience The position that required microwell plate 406 can be fast and accurately found when picking and placing microwell plate 406, in the horizontal upper surface for being incubated for disk 506 It is circumferentially arranged to have and be incubated for the one-to-one pylon scale 510 of pylon 507, while position is provided on being incubated for pedestal 502 Sensor 511 is incubated for the location information that disk 506 rotates for recording level, guarantees the running accuracy of tower position.

To make horizontal be incubated on disk 506 that can be evenly distributed with the identical incubation pylon 507 of eight groups of structures, level is incubated for disk 506 Diameter can be relatively large, causes 505 outer diameter of driven pulley for driving it to rotate larger, and existing motor is mostly fixed rotating speed, Therefore it is incubated for the revolving speed of motor 504 for adaptation, speed changer 512 is provided on being incubated for pedestal 502, is incubated for motor 504 and passes through change Fast device 512 is sequentially connected with driven pulley 505；It is incubated under pedestal 502 specifically, speed changer 512 is fixed on by fixed plate 513 On surface, the output end of speed changer 512 extends vertically up to be incubated for 502 top of pedestal, is provided with driving pulley 514, Driving pulley 514 is sequentially connected by transmission belt and driven pulley 505, and the input terminal of speed changer 512 passes through toothed belt transmission Mechanism and incubation motor 504 are sequentially connected.

Offer on the side wall of incubator 501 into plate mouth and plate outlet 515, in order to sample-adding unit matching, it is convenient from It is dynamic to be put into microwell plate 406, into plate mouth by longitudinal gap opens up eight constituted into plate door opening 516, eight into plate door opening 516 and eight Layer microwell plate card slot 508 corresponds, and is pushing 518 into being hinged on plate door opening 516 by automatic rebounding hinge 517；Automatically Rebound hinge 517 is hydraulic hinge (full name is that torsion spring type hydraulic cushion closes door hinge) or pneumatic hinge (full name be pneumatic type from Move and close door hinge), when guaranteeing to be sent into 406 backed off after random station of microwell plate, push 518 rebounds, is closed into plate door opening 516, realizes certainly Dynamicization reduces the risk that unstable factor causes failure.

Plate outlet 515 is connected to the sealing of the front side wall of complete machine shell 1, the size of plate outlet 515 and one group of incubation pylon 507 Outer openings size be adapted, be hinged with incubator door 519 on 1 front side wall of complete machine shell corresponding with plate outlet 515, To enhance leakproofness, the ring packing that fitting is adapted to 515 opening's edge of plate outlet is provided on the medial surface of incubator door 519 Adhesive tape；It may also set up in the enabling side of incubator door 519 and consolidate magnetic support with the attracted suction of plate outlet 515, and close to suction Hall sensor is set on the plate outlet of Gu Cizuochu, when incubator door 519 is not shut completely, Hall sensor can be issued Alarm signal prompts incubator door 519 not shut；In addition, plate outlet 515 corresponding with 519 enabling side of incubator door It is provided with several incubation information indicator lights 520 in opening's edge, incubates the micropore on information indicator light 520 and one group of incubation pylon 507 Board slot 508 corresponds, and incubating information indicator light 520 can realize that different colors is shown by related software, corresponding to be incubated for The different of microwell plate 406 incubate information in pylon 507.

It is provided with the heating blower 522 with heater strip 521 on the roof of incubator 501, is provided with temperature in incubator 501 Sensor is spent, for real-time monitoring and feeds back the temperature information in incubator 501；Complete machine positioned at 519 lower section of incubator door It is provided on 1 front side wall of shell and incubates information display screen 523, can show incubation information at any time, it is convenient to grasp incubator 501 at any time Interior real-time parameter；In addition, sealing wears thermometer 524 on the roof of incubator 501, the upper end of thermometer 524 is from complete machine The roof of shell 1 is pierced by, and operator is facilitated intuitively to read temperature information.

After the completion of board is incubated through hatch unit 5, it will enter in detection unit 6 and carry out identification and susceptibility detection.

As shown in figs. 19-21, detection unit 6 includes being set to the detection pedestal 601 being incubated at 507 medial center of pylon, It is vertically arranged with the first guide rail 602 on detection pedestal 601, slides and is provided with by the first power mechanism 603 on the first guide rail 602 The information collection mechanism of lifting is driven, the first power mechanism 603 is the synchronous belt drive mechanism being arranged on detection pedestal 601, It is provided with the balance weight mechanism for preventing information collection mechanism from falling on detection pedestal 601, collecting mechanism is avoided to fall suddenly, is had anti- Shield effect.

Information collection mechanism includes the horizontal lifting frame 604 being slidably arranged on the first guide rail 602, horizontal lifting frame 604 Inner close fitting long side side wall is horizontally disposed the second guide rail 605, slides and is provided with by the second power mechanism 606 on the second guide rail 605 The side level of the sliding block 607 of driving, sliding block 607 is fixed with pallet link block 608, in pallet link block 608 far from sliding block 607 Side be fixed with detection pallet 609, detect pallet 609 on offer card hole 610 compatible with 406 bottom surface of microwell plate, use In fixing microwell plate 406, the pallet inlet and outlet 611 that detection pallet 609 is opened up from 604 short side side wall of horizontal lifting frame are passed through； It is provided with optical fiber fixed block 612 at the lower opening's edge of pallet inlet and outlet 611, the bottom of horizontal lifting frame 604 is provided with LED light 613, the light that LED light 613 issues is irradiated in optical fiber fixed block 612 after optical filter filters by optical fiber 614, through optical fiber fixed block 612 light beams come out are radiated on the plate hole of microwell plate 406 through detection pallet 609 again, finally by being covered on horizontal lifting The photoelectric signal transforming module 615 at 604 top of frame is acquired, and collected decaying optical signal is sent to single-chip microcontroller (i.e. PLC Controller), the drug resistance parameter of sample is calculated through single-chip microcontroller, completes the acquisition and detection of information.

Balance weight mechanism includes longitudinal in the door shape frame 616 on detection pedestal 601, the first guide rail 602 and information collection Mechanism is located at 616 inside of door shape frame, is vertically arranged with third on the detection pedestal 601 at 616 rear of door shape frame and leads Rail 617, the hanging axis 618 being equipped with above photoelectric signal transforming module 615 on horizontal lifting frame 604, hanging axis 618 is along door The width direction of glyph framework 616 is horizontally disposed, and the cable wire 619 on hanging axis 618 is fixed on around the top of door shape frame 616 in one end The fixed pulley 620 in portion is fixedly connected with the clump weight 621 being slidably arranged on third guide rail 617, the lower end suit of third guide rail 617 Have a resilient cushion 622, resilient cushion 622 be located at clump weight 621 it is whole under, be adapted to corresponding, the whereabouts of clump weight 621 played slow with it Punching effect.

In addition, being connected on the follower of the first power mechanism 603 to improve the stability when movement of information collection mechanism There is the first screw rod 623 extended straight up, imports and exports 611 opposite sides in horizontal lifting frame 604 and pallet and be provided with lifting spiral shell Base 624, lifting nut seat 624 are connected with the first nut being screwed on the first screw rod 623；Second power mechanism 606 is to set The synchronous belt drive mechanism on horizontal lifting frame 604 is set, is fixed on the follower of the second power mechanism 606 and the second guide rail 605 the second parallel screw rods 625, have screwed the second nut 626 on the second screw rod 625, and sliding block 607 is and the second nut 626 Connected nut slider is provided with first position sensor 627, In on the horizontal lifting frame 604 of 625 rear end of the second screw rod It is provided with sensing chip 628 on sliding block 607, shows to detect pallet when first position sensor 627 detects 628 signal of sensing chip 609 are retracted to extreme position；L-shaped connector 629 is provided on the horizontal lifting frame 604 of 625 front end of the second screw rod (connector 629 be sheet metal component) is provided with second position sensor 630 on connector 629, for incuding detection pallet 609 Whether microwell plate 406 is installed with.

The board buanch unit is as the combining mechanism between support plate unit 4, sample-adding unit 2 and hatch unit 5, by plate Card is transferred to sample-adding unit 2 by support plate unit 4, and the board for completing sample-adding in sample-adding unit 2 is retransferred and pushes to incubation In unit 5.

As shown in Figure 22,23, board buanch unit 7 includes the longitudinal substrate that fitting is fixed on 202 leading flank of backboard 701, being horizontally disposed on the leading flank of longitudinal substrate 701 has the lateral transmission belt 703 driven by horizontal drive motor 702, position In being arranged at intervals with several arm Board position sensors along its length on the longitudinal substrate 701 of 703 lower section of lateral transmission belt 704, conveying end and the incubator 501 of lateral transmission belt 703 it is corresponding into plate mouth adaptation, be installed on lateral transmission belt 703 Vertical arms plate 705；One end of vertical arms plate 705 is provided with vertical drive motor 706, the working shaft of vertical drive motor 706 End is connected with the synchronous rotation lead screw 707 positioned at 705 front side of vertical arms plate by shaft coupling, rotates synchronously the axis of lead screw 707 To consistent with 705 length direction of vertical arms plate, it is provided with the feed screw nut 708 slided above and below on rotating synchronously lead screw 707, It is provided on vertical arms plate 705 and rotates synchronously the consistent altitude location plate of 707 length direction of lead screw, in feed screw nut 708 On be provided with microwell plate transfer support bracket and nut location sensor 709 compatible with altitude location plate, altitude location plate Length should match with the move distance of feed screw nut 708, guarantee to monitor it on the entire stroke of feed screw nut 708 The location information vertically moved.

For improve vertical arms plate 705 along longitudinal direction 701 transverse movement of substrate when stability, be located on lateral transmission belt 703, It is symmetrically arranged on 701 leading flank of longitudinal substrate of lower two sides and the consistent arm panel guide of lateral 703 length direction of transmission belt 710, the length of siding guide rail 710 should be adapted with the length of lateral transmission belt 703, and vertical arms plate 705 is installed on sliding Arm plate sliding block 711 on arm panel guide 710 is fixedly connected with；In addition, dividing on the longitudinal substrate 701 at lateral 703 both ends of transmission belt It is not provided with the arm plate limited post 712 of block vertical arms plate 705, when can effectively avoid the positioning failure of horizontal drive motor 702 There is derailing risk in (when i.e. horizontal drive motor 702 breaks down) vertical arms plate 705, and arm plate limited post 712 is vertical to be fixed on Screw on substrate 701 facilitates materials.

For improve feed screw nut 708 along longitudinal direction 705 vertical motion of arm plate when stability, in the front side of vertical arms plate 705 Setting and the synchronous rotation consistent nut guide rail 713 of 707 length direction of lead screw on face, the length of nut guide rail 713 should be with silk The movement travel of thick stick nut 708 is adapted, feed screw nut 708 and the lead screw connection sliding block being slidably arranged on nut guide rail 713 It is fixedly connected with.The spiral shell of block feed screw nut 708 is respectively arranged on the vertical arms plate 705 rotated synchronously at 707 both ends of lead screw Female limited post 714, (i.e. vertical drive motor 706 breaks down when the positioning of vertical drive motor 706 can effectively be avoided to fail When) the appearance derailing risk of feed screw nut 708.

As shown in figure 24, microwell plate transfer support bracket includes being fixed on the board extended horizontally forward on feed screw nut 708 Cantilevered leg 715 is shifted, horizontal be fixed with is held in the palm with the board transfer to match into plate door opening 516 in board transfer cantilevered leg 715 Frame 716 is provided with bracket sensors in place 717 on the side of board transfer carriage 716, and whether real-time monitoring microwell plate 406 It transports in place.In addition, being provided with block micropore on the separate board transfer 715 end side side of cantilevered leg of board transfer carriage 716 The buffering blob of viscose 718 of plate 406, microwell plate 406 along longitudinal direction 701 transverse movement of substrate when buffer function is played to it；Board transfer Bracket 716 is evenly distributed in the upper surface 10 × 12 microwell plate location holes 719, In compatible with the plate hole bottom surface of microwell plate 406 It is offered respectively manually on 716 two sides of board transfer carriage between microwell plate location hole 719 and board transfer cantilevered leg 715 Grab groove 720, the interference of other component when taking, putting microwell plate 406 for evading.

In addition to avoid whole system in the process of running, internal cable influences operation, synchronous in the X-axis of sample-adding unit It is single in detection on the motion profile of tape handler 204, Y-axis synchronous belt drive mechanism 207 and Z axis synchronous belt drive mechanism 210 On first power mechanism 603 of member and the motion profile of the second power mechanism 606, in the lateral transmission belt of board buanch unit 703 and microwell plate transfer support bracket motion profile on be provided with drag chain 8, cable is hidden in drag chain 8, is formed effective Protection prevents and there is interference or route abrasion between other moving components.

The course of work of the utility model is as follows:

Support plate unit 4 can be scanned the microwell plate 406 in board relieving mechanism first, while specimen discerning record Member 3 can be scanned the specimen bottle 306 being placed on annular pallet 305, and system can automatically carry out microwell plate 406 and specimen bottle Classification information matches, and board buanch unit takes out microwell plate 406 out of board storehouse mechanism after successful match, and transfers them to On microwell plate bearing device, it is completed at the same time the movement of uncapping of 406 plate of microwell plate；Then system can be according to the classification of microwell plate 406 Information chooses corresponding specimen bottle 306 automatically, and specimen bottle 306 is gone to close to pipette tips handler side；Sample-adding is single later The sample loading gun operation of member 2, completes the installing of disposable imbibition pipette tips 223, after having installed disposable imbibition pipette tips 223, sample loading gun It reruns at the specimen bottle 306 to imbibition and carries out imbibition；Sample loading gun, which is run to, later carries out liquid feeding on microwell plate bearing device； After the completion of being loaded, board buanch unit 7 hold up again sample-adding complete microwell plate 406, and be transported in incubator 501 into Row is incubated for, and simultaneously, sample loading gun can be run at pipette tips handler, and used disposable imbibition pipette tips 223 are laid down, Wait installing next time；After the completion of incubation, detection unit 6 can take microwell plate 406 from the inside for being incubated for pylon 507 away, into Row identification and susceptibility detection put back to again after detect and are incubated for the original position of pylon 507, and the data that will test out reflect arrive in real time On computer, a whole set of movement is completed.

Claims (10)

1. a kind of full automatic microorganism identification and Analysis of Drug Susceptibility system, it is characterised in that: including complete machine shell, in the complete machine shell Sample-adding unit, specimen discerning recording unit, support plate unit, hatch unit, detection unit and board is provided in the inner cavity of body to turn Move unit；

The sample-adding unit is automatically performed handling pipette tips, gun body imbibition and board sample-adding；

The specimen discerning recording unit is located at the sample-adding unit side, is scanned record to the specimen bottle for being loaded with sample And automatic selection；

The support plate unit is located at the other side of the sample-adding unit, for loading and scanning record board；

The hatch unit, the board completed to sample-adding incubate；

The detection unit carries out identification to the board after incubation and susceptibility detects；

The board buanch unit is as the combining mechanism between support plate unit, sample-adding unit and hatch unit, by board by carrying Plate unit is transferred to sample-adding unit, then is pushed in hatch unit by the transfer of sample-adding unit.

2. full automatic microorganism identification according to claim 1 and Analysis of Drug Susceptibility system, it is characterised in that: the sample-adding is single Member includes being installed on the intracorporal braced frame of complete machine shell, and longitudinal direction is fixedly arranged on rear side of the braced frame between two columns Backboard；Being horizontally disposed on the trailing flank of the backboard has by the motor-driven X-axis synchronous belt drive mechanism of X-axis, the X-axis The cantilevered leg extended horizontally forward is fixed on the synchronous belt of synchronous belt drive mechanism, in the cantilevered leg be horizontally disposed with have by The Y-axis synchronous belt drive mechanism of y-axis motor driving, is fixed with vertically downward on the synchronous belt of the Y-axis synchronous belt drive mechanism The sample arm of extension is vertically arranged with by the motor-driven Z axis synchronous belt drive mechanism of Z axis, the Z axis on the sample arm The sample loading gun of liquid sucting port vertically downward is fixed on the synchronous belt of synchronous belt drive mechanism；Under the motion profile of the sample arm Side is provided with microwell plate bearing device and pipette tips handler.

3. full automatic microorganism identification according to claim 2 and Analysis of Drug Susceptibility system, it is characterised in that: the sample loading gun Imbibition pump motor on synchronous belt including being fixed on the Z axis synchronous belt drive mechanism, the working shaft of the imbibition pump motor Vertically downward, the drive lead screw of synchronous rotation is fixed with by shaft coupling in its lower end, is provided with edge on the drive lead screw The feed screw nut that its length direction moves above and below is vertically provided with and the suction pumps in the downward vertical of the drive lead screw The piston type suction pumps rifle that the shell of motor is fixedly connected with, the upper end piston rod of the piston type suction pumps rifle and the feed screw nut It is fixedly connected with, active card is equipped with the disposable imbibition pipette tips being located in pipette tips carrying case on the liquid sucting port of lower end；

The microwell plate bearing device includes support pedestal, is vertically equipped on the support pedestal by substrate driving motor band It is fixedly connected at dynamic live spindle, the upper end of the live spindle and horizontally disposed support substrate bottom surface center；The support Two sets of microwell plate support components supports are installed on substrate side by side, microwell plate support components support described in every set includes one group of micropore board bracket Frame is fixed with one group of plate lid, the height that the plate lid fixes frame is higher than the height of the micropore board bracket, two sets of microwell plate supports Micropore board bracket and plate lid on component fix frame and are laid staggeredly；

The pipette tips handler includes that the pipette tips being set on front side of the microwell plate bearing device discard storehouse, useless in the pipette tips The discarded pipette tips storage compartment for being provided in storehouse and extracting out or be put into from the leading flank of the complete machine shell is abandoned, discards the top in storehouse in pipette tips Pipette tips are offered on wall and fall mouth, are fallen above mouth in the pipette tips and are provided with support desk of the upper surface with pipette tips carrying case, In It is offered on the support desk and falls the corresponding Pear-Shaped pipette tips of mouth with the pipette tips and slough mouth.

4. full automatic microorganism identification according to claim 2 and Analysis of Drug Susceptibility system, it is characterised in that: the sample is known Other recording unit includes the specimen support seat being set to below the sample arm motion profile, vertical on the specimen support seat It is equipped with by the motor-driven sample tray rotary shaft of identification record unit, the upper end level of the sample tray rotary shaft is connected There is specimen bottle pallet connecting plate, activity is placed with annular pallet, edge on the annular pallet on the specimen bottle pallet connecting plate Several card slots for inserting specimen bottle circumferentially are evenly equipped with, are pasted with product export item respectively on the inside and outside side wall of the specimen bottle Code and patient information bar code；Be installed with respectively on the specimen support seat of the annular pallet medial and lateral on same specimen bottle The product export bar code and the corresponding barcode scanner of patient information barcode position；In the specimen bottle pallet connecting plate Lower surface be fixed with annular code-disc, be provided with code-disc origin position on the specimen support seat of the annular code-disc side Set sensor and code-disc indexing position sensor.

5. full automatic microorganism identification according to claim 2 and Analysis of Drug Susceptibility system, it is characterised in that: the support plate list Member includes being set to microwell plate bearing device side firm banking, passes through spaced a pair on the fixed base Vertical supporting plate is fixed with board relieving mechanism；

The board relieving mechanism includes the bottom cover being horizontally located on the two vertical supporting plates, offers board on the bottom cover Liberation port, by the guide pin active card that is fixed on bottom cover equipped with rectangle ring structure at the upper edge of the board liberation port Opening-closing plate；The opening-closing plate is docked by the U-shaped thin plate that a pair moves toward one another, and passes through rotation at the docking of the two U-shaped thin plates Pivoted housing is linked together, and the bottom wall thin plate opposite side of two U-shaped thin plates is provided with one group of symmetrical claw, wherein a U-shaped is thin The return spring that outer end is connected with the bottom cover, the draw direction of the return spring and the U-shaped thin plate are provided on plate It is consistent to open and close direction；Board release motor, the working shaft of the board release motor are installed on the lower surface of the bottom cover On be coaxially fixed with board release lead screw, the axis direction of board release lead screw is consistent with the folding direction of two U-shaped thin plates, It is provided with the nut seat for driving the folding of two U-shaped thin plates on board release lead screw, is spaced setting on board release motor Have a pair of for monitoring the distance position sensor of the nut seat movement travel；Fastening in the top of the two U-shaped thin plates has The connection pedestal being fixedly connected with the bottom cover, offers on the connection pedestal and the consistent board of the board liberation port falls Mouthful, U-shaped through slot corresponding with the information bar code position on microwell plate is offered at a side of board whereabouts mouth；

Board storehouse mechanism is provided on the board relieving mechanism, board storehouse mechanism is described including being vertically located in The block column of board whereabouts mouth four corners, the upper end of the block column are linked together by connecting top plate, formed with it is described Microwell plate compatible board storehouse storehouse, magnetic attracting door with handles is hinged in the side in board storehouse storehouse, with institute It states and Hall sensor is installed on the attracted block column of magnetic attracting door.

6. full automatic microorganism identification according to claim 2 and Analysis of Drug Susceptibility system, it is characterised in that: the incubation is single Member includes the incubator that the sample-adding unit side is arranged in, and incubation pedestal, the incubation bottom are provided in the incubator The upper surface of seat is horizontally disposed thin-wall bearing, and the inner ring of the thin-wall bearing is fixedly connected with pedestal is incubated for, covers admittedly on outer ring Having by being incubated for motor-driven driven pulley, the upper surface of the driven pulley is fixedly connected with the horizontal disk that is incubated for coaxially laid, Horizontal be incubated for is distributed along the circumference with the incubation pylon of several groups opening outwardly on disk, longitudinal gap row in the incubation pylon Several layers microwell plate card slot is shown, every group of incubation pylon is fixed by a pin to horizontal incubation disk upper surface；

Offered on the side wall of the incubator into plate mouth and plate outlet, it is described into plate mouth by longitudinal gap open up it is several into Plate door opening is constituted, described to correspond into plate door opening and the microwell plate card slot, into passing through automatic rebounding hinge on plate door opening It is hinged with and pushes；The plate outlet is connected to the sealing of the front side wall of the complete machine shell, the size of plate outlet and one group of incubation tower The outer openings size of frame is adapted, and is hinged with incubator door on complete machine shell front side wall corresponding with the plate outlet； It is provided with the heating blower with heater strip on the roof of the incubator, is provided with temperature sensor in incubator, is located at institute It states and is provided with incubation information display screen on the complete machine shell front side wall below incubator door.

7. full automatic microorganism identification according to claim 6 and Analysis of Drug Susceptibility system, it is characterised in that: in the incubation Speed changer is provided on pedestal, the speed changer is fixed on by fixed plate and is incubated in base lower surface, the output end of speed changer Extend vertically up to be incubated for above pedestal, be provided with driving pulley, the driving pulley by transmission belt and it is described from The input terminal of movable belt pulley transmission connection, speed changer is connect by synchronous drive mechanism with the incubation motor drive；It is incubated with described It educates and is provided with several incubation information indicator lights in the corresponding plate outlet opening's edge in case door enabling side, the incubation information refers to Show that the microwell plate card slot on incubation pylon described in lamp and one group corresponds.

8. full automatic microorganism identification according to claim 6 and Analysis of Drug Susceptibility system, it is characterised in that: the detection is single Member includes the detection pedestal being set at the incubation pylon medial center, is vertically arranged with first on the detection pedestal and leads Rail, sliding is provided with by the information collection mechanism of the first power mechanism driving lifting on first guide rail, is detected and is set on pedestal It is equipped with the balance weight mechanism for preventing the information collection mechanism from falling；

The information collection mechanism includes the horizontal lifting frame being slidably arranged on first guide rail, in the horizontal lifting frame Abutting long side side wall is horizontally disposed the second guide rail, and sliding is provided with the cunning driven by the second power mechanism on second guide rail The side level of block, the sliding block is fixed with pallet link block, is fixed with inspection far from the side of sliding block in the pallet link block Survey pallet, it is described detection pallet opened up from the horizontal lifting frame short side side wall pallet inlet and outlet across；In the pallet It is provided with optical fiber fixed block at the lower opening's edge of inlet and outlet, the bottom of the horizontal lifting frame is provided with LED light, the LED light The light of sending is radiated on the detection pallet by optical fiber through the optical fiber fixed block, is covered at the top of the horizontal lifting frame There is photoelectric signal transforming module.

9. full automatic microorganism identification according to claim 8 and Analysis of Drug Susceptibility system, it is characterised in that: the counter weight machine Structure includes longitudinal in the door shape frame on the detection pedestal, and first guide rail and information collection mechanism are located at the door word On the inside of shape frame, it is vertically arranged with third guide rail on the detection pedestal at door shape frame rear, on the horizontal lifting frame The hanging axis being located above the photoelectric signal transforming module, width direction water of the hanging axis along the door shape frame are installed Flat setting, the cable wire that one end is fixed on hanging axis are led around the fixed pulley of door shape frame roof with the third is slidably arranged in Clump weight on rail is fixedly connected with.

10. full automatic microorganism identification according to claim 6 and Analysis of Drug Susceptibility system, it is characterised in that: the board Buanch unit includes the longitudinal substrate that fitting is fixed on the backboard leading flank, horizontal on the leading flank of the longitudinal substrate It is provided with the lateral transmission belt driven by horizontal drive motor, along its length on the longitudinal substrate below the lateral transmission belt Degree direction is arranged at intervals with several arm Board position sensors, the conveying end of lateral transmission belt and fitting into plate mouth for the incubator With correspondence, vertical arms plate is installed on lateral transmission belt；

One end of the vertical arms plate is provided with vertical drive motor, the working shaft end of the vertical drive motor passes through connection Axis device is connected with the synchronous rotation lead screw on front side of vertical arms plate, the axial direction for rotating synchronously lead screw and the vertical arms plate Length direction is consistent, rotate synchronously lead screw on be provided with the feed screw nut slided above and below, be provided on vertical arms plate with together Walk the consistent altitude location plate of rotational lead screw length direction, be provided on the feed screw nut microwell plate transfer support bracket and with The compatible nut location sensor of the altitude location plate；

The microwell plate transfer support bracket includes being fixed on the board transfer cantilevered leg extended horizontally forward on the feed screw nut, In board transfer cantilevered leg it is horizontal be fixed with the board transfer carriage to match into plate door opening, in the board Bracket sensors in place is provided on the side of transfer carriage.