CN209678553U - Sampling capsule and sampling capsule system - Google Patents
Sampling capsule and sampling capsule system Download PDFInfo
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- CN209678553U CN209678553U CN201821697788.6U CN201821697788U CN209678553U CN 209678553 U CN209678553 U CN 209678553U CN 201821697788 U CN201821697788 U CN 201821697788U CN 209678553 U CN209678553 U CN 209678553U
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- sampling capsule
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- 238000005070 sampling Methods 0.000 title claims abstract description 242
- 239000002775 capsule Substances 0.000 title claims abstract description 94
- 238000002347 injection Methods 0.000 claims abstract description 93
- 239000007924 injection Substances 0.000 claims abstract description 93
- 238000005192 partition Methods 0.000 claims abstract description 48
- 238000004891 communication Methods 0.000 claims description 18
- 238000003384 imaging method Methods 0.000 claims description 9
- 230000003447 ipsilateral effect Effects 0.000 claims description 6
- 239000007788 liquid Substances 0.000 claims description 6
- 230000033001 locomotion Effects 0.000 claims description 6
- 230000007246 mechanism Effects 0.000 claims description 6
- 229910045601 alloy Inorganic materials 0.000 claims description 5
- 239000000956 alloy Substances 0.000 claims description 5
- 238000001816 cooling Methods 0.000 claims description 5
- 210000001035 gastrointestinal tract Anatomy 0.000 claims description 5
- 238000010438 heat treatment Methods 0.000 claims description 5
- 230000003902 lesion Effects 0.000 claims description 5
- 238000000926 separation method Methods 0.000 claims description 5
- 238000011084 recovery Methods 0.000 claims description 4
- 230000029087 digestion Effects 0.000 claims description 2
- 239000000523 sample Substances 0.000 abstract description 45
- 239000013068 control sample Substances 0.000 abstract description 3
- 230000006872 improvement Effects 0.000 description 21
- 230000001079 digestive effect Effects 0.000 description 16
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 16
- 238000010586 diagram Methods 0.000 description 9
- 230000000694 effects Effects 0.000 description 8
- 238000000034 method Methods 0.000 description 4
- 230000005540 biological transmission Effects 0.000 description 3
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- 238000009434 installation Methods 0.000 description 3
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- 238000012790 confirmation Methods 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 238000000338 in vitro Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 238000007789 sealing Methods 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 238000002604 ultrasonography Methods 0.000 description 2
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- 238000004026 adhesive bonding Methods 0.000 description 1
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- 230000009286 beneficial effect Effects 0.000 description 1
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- 230000007797 corrosion Effects 0.000 description 1
- 238000005260 corrosion Methods 0.000 description 1
- 230000001808 coupling effect Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000005611 electricity Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 239000010931 gold Substances 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 238000010827 pathological analysis Methods 0.000 description 1
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- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Abstract
The utility model provides a kind of sampling capsule, encloses including shell, the partition wall in the shell, by the partition wall with the shell for being located at first side of partition wall and sets the sampling pool formed, the interior injection port on the partition wall, the outer injection port on the shell for being located at described partition wall second side, be connected to the sampling channel of the outer injection port and the interior injection port, open or close the switch block of the sampling channel.The sampling channel is opened when the sampling capsule reaches alimentary canal position to be detected by the switch block, realizes sample introduction;After sample introduction, the sampling channel is closed, prevents sample leakage or contaminated;And by the opening time for controlling the sampling channel, it can accurately control sample volume.In addition, opening or closing by sampling channel described in the switch block active control, can be common to any alimentary canal position, versatility is higher.
Description
Technical field
This application involves the field of medical instrument technology more particularly to a kind of versatility height, sampling time and sampling quantity can
Accurate control and the sampling capsule and sampling capsule system that sample can be prevented to be leaked or pollute after sampling.
Background technique
Sampling capsule is a kind of intelligent capsule sampled into alimentary canal position to digestive juice.Under normal conditions, it adopts
Sample capsule includes sampling cavity, the thief hatch and sample tap that are connected to sampling cavity;After reaching specific alimentary canal position, thief hatch
It opens, digestive juice enters sampling cavity;After sampling capsule removes in vitro, digestive juice is taken out from sample tap and carries out pathological analysis.
Existing sampling capsule, thief hatch uses material degradable under specific alimentary canal site environment, when the sampling
When capsule reaches corresponding alimentary canal position, which forms thieff hatch, adopts so that digestive juice enters under inside and outside differential pressure
In sample capsule.However, this sampling capsule, on the one hand, different environment in the digestive tract are different, the versatility of this kind of sampling capsule
Difference;On the other hand, sampling quantity is uncontrollable, and after sampling, thieff hatch cannot be again switched off, and sample is easy leakage or by it
He pollutes liquid.
In view of this, it is necessary to provide a kind of improved sampling capsule and sampling capsule systems, to solve the above problems.
Utility model content
A kind of the purpose of this utility model is to provide versatilities high, sampling time and sampling quantity can accurately control and
The sampling capsule and sampling capsule system that sample can be prevented to be leaked or pollute after sampling.
To realize above-mentioned purpose of utility model, the utility model provides a kind of sampling capsule, including shell, be set to it is described outer
Partition wall in shell is enclosed with the shell for being located at first side of partition wall by the partition wall and sets the sampling pool formed, sets
In the interior injection port on the partition wall, the outer injection port on the shell for being located at described partition wall second side, connection
The sampling channel of the outer injection port and the interior injection port, the switch block for opening or closing the sampling channel.
Enclose that set the wall to form the sampling channel include first be oppositely arranged as a further improvement of the utility model,
Wall and the second wall, at least partly described first wall are elastic wall;The switch block forces in the elastic wall, described in adjustment
Spacing distance between elastic wall and second wall, so that the elastic wall fits in the second wall closing sampling and leads to
The sampling channel is opened far from second wall in road.
First wall and second wall are elastic wall as a further improvement of the utility model, and described the
One wall and second wall are wholely set, and the sampling channel is a multi-pass pipe, and part nozzle is connect with the interior injection port,
Other part nozzle is connect with the outer injection port.
Second wall is arranged close to the partition wall as a further improvement of the utility model, and first wall is set
It is placed in the side that the sampling channel deviates from the partition wall.
As a further improvement of the utility model, second wall be the partition wall, first wall be with it is described
The spaced elastic wall of partition wall, the outer injection port is set between the partition wall and the elastic wall, described
The sampling channel is formed between elastic wall and the partition wall.
The switch block includes driving the elastic wall close to described second as a further improvement of the utility model,
The driving unit of wall, the control unit with the driving unit communication connection.
The driving unit includes micro- with described control unit communication connection as a further improvement of the utility model,
Motor, the jacking block being connect with the rotor threads of the micro machine;When the rotor rotates, the top is converted by being threadedly engaged
The linear motion of block, to force in the elastic wall.
The jacking block is not connected with the elastic wall as a further improvement of the utility model,;Or the jacking block with
The elastic wall is connected.
As a further improvement of the utility model, the switch block further include on the inner wall for be set to the shell with
Limit the sliding rail that the jacking block moves along a straight line.
The driving unit includes driving the elastic wall close to or far from the as a further improvement of the utility model,
The mobile driving mechanism of the movable blocks of two walls, driving movable block, the driving mechanism include that one end with movable block connect the other end
The marmem and described control unit communication connection connecting with fixed block are to carry out temperature control to marmem
Temperature control element;Wherein, when temperature restores threshold value lower than shape, the marmem has first shape state, mobile
The distance between block connection and fixed block are first distance;When temperature is higher than shape recovery threshold value, the marmem tool
There is the second shape state, the distance between movable block connection and fixed block are second distance, and first distance is less than or greater than second
Distance;And biggish distance is configured as in first distance and second distance, movable block force in the elastic wall make it is described
Elastic wall fits in second wall, closes the sampling channel.
The temperature control element is heating element as a further improvement of the utility model, and the first distance is greater than institute
State second distance.
The temperature control element is cooling element as a further improvement of the utility model, and the first distance is less than institute
State second distance.
The marmem is set between movable block, fixed block as a further improvement of the utility model, and institute
Stating the both ends of marmem, two sides opposite with movable block, fixed block are connect respectively;Or the marmem is set to
Movable block, fixed block it is ipsilateral, and the both ends of the marmem are remembered with movable block, fixed block towards the shape respectively
The side for recalling alloy is connected;Or the marmem be set to movable block, fixed block it is ipsilateral, and the shape memory close
The both ends of gold pass through the connector two sides opposite with movable block, fixed block respectively and are connected.
One group of movable block is opposite with a marmem with fixed block as a further improvement of the utility model,
It answers;Or multiple groups movable block is corresponding with a marmem with fixed block;
A marmem and a temperature control element are corresponding or more as a further improvement of the utility model,
A marmem is corresponding with a temperature control element.
As a further improvement of the utility model, the switch block further include on the inner wall for be set to the shell with
Limit the auxiliary block that the movable block moves along a straight line.
The switch block as a further improvement of the utility model, further include:
With the sensor of described control unit communication connection, the sensor is for acquiring physiological parameter in the digestive tract
And/or image information;
With the storage module of described control unit communication connection, the storage module is for storing different parts in alimentary canal
Normal physiological parameter and/or image information, possible lesion when physiological parameter and/or image information.
The sensor is that imaging sensor or pH sensor or ultrasound pass as a further improvement of the utility model,
At least one of sensor;When the sensor includes imaging sensor, the part shell is transparent;The sensor packet
When including pH sensor, there is window on the shell, pH sensor is contacted by the window with the alimentary canal liquid.
The sampling capsule further includes connecting to communicate with extraneous processing terminal as a further improvement of the utility model,
The wireless transport module connect.
The quantity of the interior injection port is at least two, described at least two as a further improvement of the utility model,
Interior injection port is uniformly distributed or is randomly distributed on the partition wall;The quantity of the outer injection port is at least two, at least two
A outer injection port is uniformly distributed or is randomly distributed on the shell along the circumferential direction of the shell.
The sampling capsule includes that the sampling channel is connected to institute simultaneously as a further improvement of the utility model,
There are the interior injection port and the outer injection port;Or the sampling capsule includes at least two sampling channels, the sampling
Channel is connected at least one described interior injection port and at least one described outer injection port.
The sampling capsule further includes the institute positioned at first side of partition wall as a further improvement of the utility model,
The sample tap stated on shell and be connected to the sampling pool.
To realize above-mentioned purpose of utility model, the utility model also provides a kind of sampling capsule system, including above-mentioned sampling
Capsule, the extraneous processing terminal with switch block communication connection.
Compared with prior art, the utility model has the beneficial effects that the sampling capsule of the utility model is opened by described
Component is closed, when the sampling capsule reaches alimentary canal position to be detected, opens the sampling channel, digestive juice is through outer sample introduction
Mouth, sampling channel, interior injection port enter the sampling pool, realize sample introduction;After sample introduction, the sampling channel is closed, is prevented
Only sample leakage or contaminated;And by the opening time for controlling the sampling channel, it can accurately control sample volume.Separately
Outside, opening or closing by sampling channel described in the switch block active control, is not influenced by alimentary canal site environment,
It can be common to any alimentary canal position, versatility is higher.
Detailed description of the invention
Fig. 1 is structural schematic diagram of the sampling capsule of one preferred embodiment of the utility model when sampling channel is closed;
Fig. 2 is structural schematic diagram of the sampling capsule shown in FIG. 1 when sampling channel is opened;
Fig. 3 is the diagrammatic cross-section of the multi-pass pipe in one preferred embodiment of the utility model;
Fig. 4 is the diagrammatic cross-section of the multi-pass pipe in the utility model another preferred embodiment;
Fig. 5 be the utility model another preferred embodiment sampling capsule in sampling channel open when structural schematic diagram;
Fig. 6 is sampling capsule shown in fig. 5 structural schematic diagram when sampling channel is closed;
Fig. 7 be the utility model another preferred embodiment sampling capsule in sampling channel open when structural schematic diagram;
Fig. 8 is sampling capsule shown in Fig. 7 structural schematic diagram when sampling channel is closed.
Specific embodiment
The application is described in detail below with reference to specific embodiment shown in the drawings.But these embodiments are simultaneously
The application is not limited, structure that those skilled in the art are made according to these embodiments, method or functionally
Transformation is all contained in the protection scope of the application.
In each diagram of the application, for the ease of illustration, structure or partial certain sizes can be relative to other knots
Structure or part are exaggerated, and therefore, are only used for the basic structure of the theme of diagram the application.
In addition, the term of the representation space relative position used herein such as "upper", " top ", "lower", " lower section " is
A unit as shown in the drawings or feature are described for the purpose convenient for explanation relative to another unit or feature
Relationship.The term of relative space position can be intended to include equipment in use or work other than orientation as shown in the figure not
Same orientation.For example, being described as being located at other units or feature " below " or " under " if the equipment in figure overturn
Unit will be located at other units or feature " top ".Therefore, exemplary term " lower section " can include above and below both
Orientation.Equipment can otherwise be directed (be rotated by 90 ° or other directions), and be interpreted accordingly it is used herein with it is empty
Between relevant description language.
It please refers to shown in FIG. 1 to FIG. 8, is the sampling capsule 100 and its internal structure of the utility model preferred embodiment
Schematic diagram.
It please refers to shown in FIG. 1 to FIG. 2 and Fig. 5~Fig. 8, the sampling capsule 100 includes shell 1, is set in the shell 1
Partition wall 2, enclosed by the partition wall 2 with the shell 1 for being located at 2 first side of partition wall and set the sampling pool 3 formed, set
In the interior injection port 41 on the partition wall 2, the outer injection port on the shell 1 for being located at described 2 second side of partition wall
42, it is connected to the sampling channel 43 of the outer injection port 42 and the interior injection port 41, opens or closes the sampling channel 43
Switch block 5.
Under normal circumstances, when sampling capsule 100 is in the alimentary canal position for needing to check or reaches the digestion with lesion
When road position, then sampled.When the sampling capsule 100 reaches the alimentary canal position for needing to sample, by described
Switch block 5 opens the sampling channel 43, and digestive juice is through described in outer injection port 42, sampling channel 43, the entrance of interior injection port 41
Sampling pool 3 realizes sample introduction;After sample introduction, the sampling channel 43 is closed, prevents sample leakage or contaminated;And lead to
The opening time for controlling the sampling channel 43 is crossed, sample volume can be accurately controlled.In addition, actively by the switch block 5
Opening or closing for the sampling channel 43 is controlled, is not influenced by alimentary canal position particular surroundings, any disappear can be common to
The position Hua Dao, versatility are higher.
After the sampling capsule 100 takes out in vitro, the scheme for taking out digestive juice includes but is not limited to: opening the sampling
Channel 43 is used for pathology so that the digestive juice is flowed out through interior injection port 41, the sampling channel 43, the outer injection port 42
Analysis.Alternatively, the sampling capsule 100 further include positioned at 2 first side of partition wall the shell 1 on and with the sampling
The sample tap 6 that pond 3 is connected to, using soft materials such as rubber at the sample tap 6, by equipment such as syringes from the sample tap
6, which are pierced into the sampling pool 3, is sampled.
Specifically, the shell 1 uses any material that is harmless and will not being digested corrosion, and length is in 30mm
Within, such as 27mm;Diameter is within 12mm, such as 11.6mm;Any part in the digestive tract can be entered well, carry out
Sampling.Also, the shell 1 is spliced to form by least two parts, is installed convenient for the setting of internal structure.Such as shown in Fig. 1, institute
State shell 1 by be distributed along 100 length direction of sampling capsule the first shell 11, second housing 12 and 13 3, third shell
It is grouped as, and passes through the connection such as screw thread, viscose between three parts.
The partition wall 2 is wholely set with the shell 1 for being located at 2 first side of partition wall, the sampling of formation
The leakproofness in pond 3 is preferable;Or the partition wall 2 and 1 split settings of the shell that are located at 2 first side of partition wall, the two
The leakproofness of junction will guarantee that the sampling pool 3 is able to maintain the vacuum degree needed for it.
The sampling pool 3 is vacuum cavity, and volume is greater than 0.3mL, such as 0.4mL~0.7mL;Vacuum degree can be -90kPa
~-80kPa guarantees that collectable digestive juice volume is greater than 0.3mL.Before use, the sampling channel 43 is opened, by true
Pocket extracts the air in the sampling pool 3, after vacuum degree required for reaching, the sampling channel 43 is closed, so that described
Sampling pool 3 maintains the vacuum degree needed.In use, opening institute when the sampling capsule 100 reaches the alimentary canal position needed
Sampling channel 43 is stated, the digestive juice enters in the sampling pool 3 under inside and outside differential pressure effect, completes sampling.
Preferably, the sampling pool 3 is located at one end of 1 length direction of shell, and the sampling pool 3, the sampling are logical
Road 43, the switch block 5 are successively arranged along 1 length direction of shell, and space utilization rate is high, and is easily installed.
In the utility model, the interior injection port 41, the quantity of the outer injection port 42 are unlimited.Those skilled in the art can
With understanding: " closing the sampling channel " refer to all interior injection ports 41 of cutting and the outer injection port 42 it
Between channel.
When the quantity of the outer injection port 42 is at least two, at least two outer injection ports 42 are along the shell 1
Circumferential direction be uniformly distributed on the shell 1, the digestive juice around the sampling capsule 100 can enter the sampling pool
In 3, failure can be sampled to avoid because of alimentary canal concrete position temporarily without digestive juice or caused by digesting liquid measure deficiency.When
So, at least two outer injection ports 42 can also be randomly distributed on the shell 1 along the circumferential direction of the shell 1.
When the quantity of the interior injection port 41 is at least two, at least two interior injection ports 41 are uniformly distributed in institute
It states on partition wall 2;Sample introduction speed is fast, and the digestive juice entered in the sampling pool 3 is evenly distributed, will not be because of local digestive juice
It stacks and influences sample introduction.Certainly, at least two interior injection ports 41 can also be randomly distributed on the partition wall 2.
When the quantity of the interior injection port 41 is one, and the quantity of the outer injection port 42 is at least two, pass through
One sampling channel 43 is connected to the interior injection port 41 and all outer injection ports 42 simultaneously.Specifically, the sampling
Channel 43 includes several ports being connected to one by one with the interior injection port 41, the outer injection port 42, intermediate to be connected by communicating pipe
It connects.For having an interior injection port 41 and two outer injection ports 42, sampling channel 43 is T-shaped as shown in Figure 3.
When the quantity of the interior injection port 41 is at least two, and the quantity of the outer injection port 42 is at least two,
It can be connected to all interior injection ports 41 and all outer injection ports 42 simultaneously by a sampling channel 43.Specifically
Ground, several ports that the sampling channel 43 is connected to one by one with the interior injection port 41, the outer injection port 42, centre passes through company
Siphunculus connection.To have there are two for interior injection port 41 and two outer injection ports 42, the sampling channel 43 connects two simultaneously
Interior injection port 41 and two outer injection ports 42, the sampling channel 43 is as shown in Figure 4.
When the quantity of the interior injection port 41 is at least two, and the quantity of the outer injection port 42 is at least two,
All interior injection ports 41 and all outer injection ports 42 can also be connected by multiple sampling channels 43, and each
A sampling channel 43 is connected at least one described interior injection port 41 and at least one described outer injection port 42.With there are two tools
For interior injection port 41 and two outer injection ports 42, connection can be realized by two independent sampling channels 43, it is each
One end of a sampling channel 43 is connected to an interior injection port 41, and the other end and an outer injection port 42 connect
It is logical.When the interior injection port 41 and inconsistent 42 quantity of outer injection port, multiple independent 43 structures of sampling channel
It is modified accordingly according to the interior injection port 41 of its connection and 42 quantity of outer injection port, specific structure can refer to
Embodiment is stated, is repeated no more in this.
In addition, enclosing, to set the wall to form the sampling channel 43 include the first wall 431 and the second wall 432 being oppositely arranged, until
First wall 431 described in small part is elastic wall;The switch block 5 forces in the elastic wall, with adjust the elastic wall with
Spacing distance between second wall 432, so that the elastic wall fits in second wall 432 and closes the sampling channel
43 or the sampling channel 43 is opened far from second wall 432.It will be understood by those skilled in the art that: " the switch
Component 5 forces in the elastic wall to adjust the spacing distance between the elastic wall and second wall 432 " it include following two
Kind situation: the elastic wall adjusts the elastic wall and second wall 432 under the active control of the switch block 5 completely
The distance between;Or in view of the elastic wall itself have elastic force, the elastic wall the switch block 5 control with it is described
The distance between the elastic wall and second wall 432 are adjusted jointly under elastic force effect.
It will be appreciated by persons skilled in the art that the part-structure of first wall 431 is elastic wall or entire infrastructure
It is elastic wall, when the switch block 5 drives elastic wall to be bonded with the second wall 432, closes the sampling channel 43;It is described to open
When pass component 5 does not act on the elastic wall, the elastic wall restores under own resilient, leaves second wall 432,
Open the sampling channel 43;Or the switch block 5 directly drives the elastic wall far from second wall 432, opens institute
State sampling channel 43.
Wherein, as shown in Figure 1 to 4, first wall 431 and second wall 432 are elastic wall, and described first
Wall 431 and second wall 432 are wholely set, and the sampling channel 43 is a multi-pass pipe, part nozzle and the interior sample introduction
Mouth 41 connects, and other part nozzle is connect with the outer injection port 42, and digestive juice will not be to other structures during entrance
It causes to corrode.For example, shown in Fig. 3, when the sampling capsule 100 is equipped with 41, two outer sample introductions of interior injection port
When mouthfuls 42, the multi-pass pipe is T-shaped, one nozzle is connect with the interior injection port 41, described in other two nozzle and two
Outer injection port 42 connects.
Preferably, the second wall 432 is arranged close to the partition wall 2, and first wall 431 is set to the sampling channel 43
Away from the side of the partition wall 2, the switch block 5 is located at the side that first wall 431 deviates from the partition wall 2, institute
It states that the distance between the first wall 431 and the shell 1 are larger, is installed convenient for the setting of the switch block 5.
In this embodiment, first shell 11, second housing 12 separate at the outer thief hatch 42, not set sampling
The position of mouth 42 passes through interference fit, threaded connection or gluing knot.First wall 431 is fixed on the second housing 12,
Second wall 432 is fixed on first shell 11, convenient for the installation of the multi-pass pipe.
Alternatively, as shown in Figure 5 and Figure 6, the second wall 432 is the partition wall 2, the first wall 431 is between the partition wall 2
Every the elastic wall of setting, the outer injection port 42 is set between the partition wall 2 and the elastic wall, the elastic wall
The sampling channel 43 is formed between the partition wall 2.The switch block 5 drives the elastic wall to fit in the separation
When wall 2, the sampling channel 43 can be closed, it is preferable that will the part elastic wall corresponding with the interior injection port 41
It fits on the partition wall 2, the interior injection port 41 can be covered simultaneously, to guarantee that the sampling pool 3 is a sealing
Chamber.In this embodiment, first shell 11, second housing 12 can be arranged for integral type, embodiment as shown in Figure 1 or 2
The split type setting at the outer thief hatch 42, convenient for the installation of first wall 431.
It please refers to shown in FIG. 1 to FIG. 2, Fig. 5~Fig. 6, the switch block 5 includes driving the elastic wall close to described the
The driving unit 51 of two walls 432, the control unit 52 with 51 communication connection of driving unit, described control unit 52 is for controlling
Make the working condition of the switch block 5.
The driving unit 51 include and the micro machine 511 of 52 communication connection of described control unit, with the micro machine 511
Rotor 512 be threadedly coupled jacking block 513;When the rotor 512 rotates, the jacking block 513 is converted by being threadedly engaged
Linear motion, to force in the elastic wall.
The micro machine 511 load and the displacement generated are smaller, reduce the requirement to micro machine performance, make entirely be
System structural integrity, compact, succinct, easy sealing, sampling.The micro machine 511 includes but is not limited to general motor or stepping electricity
Machine can initiatively open or close the sampling channel 43.
In the embodiment that the jacking block 513 is not connected with the elastic wall, when the rotor 512 rotates forward, pass through
Be threadedly engaged so that the jacking block 513 along the sampling capsule 100 length direction and towards 432 direction of the second wall move
It is dynamic, and the elastic wall is pushed to fit on second wall 432, close the sampling channel 43;When the rotor 512 is reversed
When rotation, the jacking block 513 is mobile away from 432 direction of the second wall, and the elastic wall restores under own resilient, from
Second wall 432 is opened, opens the sampling channel 43, it can be achieved that sample introduction.
It will be understood by those skilled in the art that: it, can be with by controlling the displacement of the jacking block 513 along its length
The conduction amount size of the sampling channel 43 is controlled, to control the flow velocity of sampling;The displacement of jacking block 513 can also be passed through simultaneously
The duration of sampling is controlled, and then sample volume can be precisely controlled.
And in the embodiment that the jacking block 513 is connected with the elastic wall, it is only that with the unconnected difference of the two:
When the rotor 512 rotate forward when, by be threadedly engaged so that the jacking block 513 along the sampling capsule 100 length direction and
It is mobile towards 432 direction of the second wall, and the elastic wall is pushed to fit on second wall 432, close the sampling
Channel 43;When the rotor 512 rotates backward, the jacking block 513 is mobile away from 432 direction of the second wall, while actively
It pulls the elastic wall to leave second wall 432, opens the sampling channel 43;Therefore, the elastic wall is apart from described
Distance, the opening time statistics of the sampling channel 43 of two walls 432 are more accurate, more so as to the control to sample volume
Precisely.
Further, the switch block 5 further includes on the inner wall for be set to the shell 1 to limit the jacking block 513
The sliding rail 514 moved along a straight line, to prevent the jacking block 513 from rotating with the rotor 512.
In another kind of embodiment, please refers to the difference shown in Fig. 7 and Fig. 8, with FIG. 1 to FIG. 6 illustrated embodiment and mainly exist
Being identically numbered in the difference of the driving unit 51, figure indicates identical structure.
Specifically, the driving unit 51 includes driving the elastic wall close to or far from the movable block of the second wall 432
The driving mechanism that 51a, driving movable block 51a are moved, the driving mechanism include that one end connect the other end with movable block 51a and consolidates
Marmem 51b and 52 communication connection of described control unit of block 51d connection are determined to carry out to marmem 51b
Temperature controlled temperature control element 51c.Described control unit 52 is used to control described by the control to temperature control element 51c
The working condition of switch block 5.
It will be appreciated by persons skilled in the art that position of the fixed block 51d in the sampling capsule is to immobilize
, the position of elastic wall is adjusted by the movement of movable block 51a;The movable block 51a is connected or both with the elastic wall
It is separately positioned, and the movable block 51a force in mode that the elastic wall moves it and jacking block 513 force in it is described
The mode that elastic wall moves it is identical, repeats no more in this.
The movable block 51a and fixed block 51d being used in conjunction with each other are known as one group of movable block 51a and fixed block 51d.One group of shifting
Motion block 51a is corresponding with a marmem 51b with fixed block 51d;Or multiple groups movable block 51a and fixed block 51d and one
A marmem 51b is corresponding, i.e., a marmem 51b can drive multiple groups movable block 51a and fixation simultaneously
Block 51d;It can certainly multiple movable block 51a be corresponding with a fixed block 51d or movable block 51a and multiple fixations
Block 51d is corresponding, and the quantity of marmem 51b and setting position can do adaptability tune according to the arrangement of movable block 51a
It is whole.
One marmem 51b marmem 51bs and one corresponding or multiple with a temperature control element 51c
A temperature control element 51c is corresponding, i.e., the temperature change of multiple marmem 51b is controlled by a temperature control element 51c.Temperature
The quantity and arrangement mode for controlling element 51c are adaptively adjusted according to the arrangement mode of multiple marmem 51b.
The both ends of marmem 51b include but is not limited to movable block 51a, fixed block the 51d mode connecting respectively:
The marmem 51b is set between movable block 51a, fixed block 51d, and the both ends of the marmem 51b point
The two sides opposite with movable block 51a, fixed block 51d are not connect.Or the marmem 51b is set to movable block 51a, fixation
Block 51d's is ipsilateral, and the both ends of the marmem 51b are respectively with movable block 51a, fixed block 51d towards the shape
The side of memorial alloy 51b is connected.Or the marmem 51b be set to movable block 51a, fixed block 51d it is ipsilateral, and
The both ends of the marmem 51b pass through the connector two sides opposite with movable block 51a, fixed block 51d respectively and are connected.
To can drive movable block 51a to move close to or far from fixed block 51d when the length of marmem 51b changes
It is dynamic.
When temperature restores threshold value lower than shape, the marmem 51b has first shape state, movable block 51a
The distance between connection and fixed block 51d are first distance;When temperature is higher than shape recovery threshold value, the marmem
51b has the second shape state, and the distance between movable block 51a connection and fixed block 51d are second distance, and first distance is less than
Or it is greater than second distance;And biggish distance is configured as in first distance and second distance, movable block 51a forces in the bullet
Property wall makes the elastic wall fit in second wall 432, closes the sampling channel 43;In first distance and second distance
Lesser distance is configured as, and the elastic wall is under the drive of the movable block 51a or under own resilient effect with described the
The separation of two walls 432, opens the sampling channel 43.
In one type embodiment, the temperature control element 51c is heating element, and the first distance is greater than described second
Distance.When temperature restores threshold value lower than shape, marmem 51b is in the first shape state of elongation, the movable block
51a is far from the fixed block 51d, and the movable block 51a makes it fit in second wall 432 to elastic wall force,
The sampling channel 43 is in close state;It is heated when opening the heating element to the marmem 51b, so that institute
State marmem 51b temperature rise to shape restore threshold value on after, marmem 51b restore compression or it is curved
Bent or wavy second shape state, and drive movable block 51a mobile towards the fixed block 51d, distance between the two
It reduces, the elastic wall separates under the drive of the movable block 51a or under own resilient effect with second wall 432, beats
The sampling channel 43 is opened, sample introduction may be implemented;And after closing the heating element, the temperature of marmem 51b drops
After restoring under threshold temperature as low as shape, due to the round trip effect of marmem 51b, marmem 51b is again extensive
First shape state is arrived again, it is mobile away from the fixed block 51d to drive the movable block 51a, while the elastic wall being pushed to paste
Together on second wall 432, the sampling channel 43, sealed sample are closed.
In another kind of embodiment, the temperature control element 51c be cooling element, the first distance be less than described second away from
From.When temperature is higher than shape recovery threshold value, marmem 51b is in the second shape state of elongation, the movable block 51a
Far from the fixed block 51d, and the movable block 51a makes it fit in second wall 432 to elastic wall force, described
Sampling channel 43 is in close state;Cool down when opening the cooling element to the marmem 51b, so that the shape
The temperature of shape memory alloys 51b be reduced to shape restore threshold value under after, marmem 51b restore compression or bending or
Wavy first shape state, and drive movable block 51a mobile towards the fixed block 51d, distance between the two reduces,
The elastic wall separates under the drive of the movable block 51a or under own resilient effect with second wall 432, described in opening
Sampling channel 43, may be implemented sample introduction;And after closing the cooling element, the temperature of marmem 51b is increased to shape
After shape restores on threshold temperature, due to the round trip effect of marmem 51b, marmem 51b is restored to the again
It is mobile away from the fixed block 51d to drive the movable block 51a, while the elastic wall being pushed to fit in institute for two shape states
It states on the second wall 432, closes the sampling channel 43, sealed sample.
Further, the switch block 5 further includes on the inner wall for be set to the shell 1 to limit the movable block
The auxiliary block 56 that 51a is moved along a straight line, to prevent the movable block 51a from shifting.Meanwhile the auxiliary block 56 can also rise
To the effect of auxiliary installation other structures part.
It is not limited to Fig. 7 and embodiment illustrated in fig. 8, the driving unit 51 with marmem 51b is also applied for Fig. 5
With sampling channel 43 shown in fig. 6.
In addition, please referring to shown in FIG. 1 to FIG. 2, Fig. 5~Fig. 8, the switch block 5 further includes and described control unit 52
The sensor 53 of communication connection, storage module 54 etc..The sensor 53 is for acquiring physiological parameter in the digestive tract and/or figure
As information, the information collected can be used for system positioning, to judge the location of described sampling capsule 100 and sampling is
It is no to need to carry out.The storage module 54 is for storing the normal physiological parameter of different parts and/or image letter in alimentary canal
Physiological parameter and/or image information when breath, possible lesion, the letter that described control unit 52 can obtain the sensor 53
Breath is compared with the physiological parameter of storage and/or image information, thus judge 100 location of described sampling capsule and
Whether sampling needs to carry out.
The sensor 53 is imaging sensor or at least one of pH sensor or ultrasonic sensor;With a variety of
When sensor 53, judge more accurate.
Specifically, when the sensor 53 includes imaging sensor, the part shell 1 is transparent, described image
Sensor can obtain external alimentary canal image.
Or the sensor 53 include ultrasonic sensor when, the gastral physiological parameter is obtained by ultrasonic wave, this
Shi Suoshu shell 1 makes as the acoustic medium between ultrasonic sensor and the object to be imaged such as alimentary canal inner wall, acoustical behavior
Energy good acoustical coupling effect is provided, improve ultrasonic imaging quality.
Or the sensor 53 has window on the shell 1, pH sensor passes through the window when including pH sensor
It is contacted with the alimentary canal liquid.It will be appreciated by persons skilled in the art that the window is configured that alimentary canal liquid only can be with institute
It states the detection position contact of pH sensor and cannot be in contact with other component.
Further, the sampling capsule 100 further includes to the wireless transmission mould with extraneous processing terminal communication connection
The collected information of the sensor 53 is transferred to extraneous processing terminal by the wireless transport module 55 by block 55, extraneous
Processing terminal handles data information, can more accurately judge whether the location of described sampling capsule 100 and sampling need
Carry out;Or extraneous processing terminal updates the information of the memory, controller by the wireless transport module 55.In addition,
It can also show that check to doctor, doctor can lead by display instrument in real time by the information that the sensor 53 obtains
It is dynamic to send sampling instruction, it is sampled.
In this embodiment, the storage module 54 be also used to store by extraneous processing terminal transmit Lai information.
It by taking the embodiment with wireless transport module 55 as an example, will illustrate how to assist controlling by each sensor 53 below
Make the working condition of the sampling capsule 100.
When the sensor 53 is imaging sensor, the image of acquisition is transmitted to outside by the wireless transport module 55
Boundary's processing terminal, extraneous processing terminal handle the image of acquisition, by adopting described in human eye, computer vision algorithms make identification
Alimentary canal position locating for sample capsule 100.In addition, doctor or algorithm can also judge some lesion presence or absence by image,
It determines whether to need to sample.If desired it samples, then extraneous processing terminal is by the wireless transport module 55 to the control
The information that the transmission of unit 52 processed needs to sample, described control unit 52 control the switch block 5 and open the sampling channel 43,
It is sampled.Specifically, when the special image of appearance is identified or occurs other special integrated informations, that is, reach sampling and want
It asks, external world's processing terminal can send prompt information Xiang doctor and wait doctor's confirmation, or directly pass through wireless transport module 55
Sampling instruction is sent to sampling capsule 100, starts to sample.
When the sensor 53 is ultrasonic sensor, similar to the use process of above-mentioned imaging sensor, difference is only that
Image is B ultrasound image, is repeated no more in this.
When the sensor 53 is pH sensor, the pH value of acquisition is transmitted to the external world by the wireless transport module 55
Processing terminal, to carry out the position that processing determines the sampling capsule 100 to the pH value of acquisition, to decide whether to be adopted
Sample.If desired it samples, then extraneous processing terminal needs to adopt by the wireless transport module 55 to the transmission of described control unit 52
The information of sample, described control unit 52 control the switch block 5 and open the sampling channel 43, sampled.Specifically, when
When there is special pH value, the fluctuation of special pH value curve, that is, reach sampling request, external world's processing terminal can be sent out Xiang doctor
It send prompt information to wait doctor's confirmation, or sampling instruction is directly sent to sampling capsule 100 by wireless transport module 55, start
Sampling.
The sampling capsule 100 further includes providing the battery (not shown) of power supply to each structure of the switch block 5, with
Guarantee described control unit 52, the driving unit 51, the wireless transport module 55, the storage module 54, the sensing
The normal work of device 53.
The utility model also provides a kind of sampling capsule system, including any one of the above sampling capsule 100 and with switch
The extraneous processing terminal of 5 communication connection of component.Specifically, the switch block 5 includes at least the work for controlling the switch block 5
Make the control unit 52 of state and the wireless transport module 55 of 52 communication connection of control unit, external world's processing terminal passes through
The wireless transport module 55 and 52 communication connection of described control unit, to control the working condition of the sampling capsule 100;Its
His structure is repeated no more such as foregoing description in this.
The utility model also provides a kind of control method based on above-mentioned sampling capsule 100, includes the following steps: that judgement is
It is no to need to sample, if so, the switch block 5 opens the sampling channel 43;After sampling, the switch block 5 is closed
The sampling channel 43.Judge whether to need to sample and can repeat no more by any one of the above describing mode in this.It is described to open
The mode that pass component 5 opens or closes the sampling channel 43 is repeated no more using any one of the above in this.
In conclusion the sampling capsule 100 of the application is by the switch block 5, the sampling capsule 100 reach to
When the alimentary canal position of detection, the sampling channel 43 is opened, digestive juice is through outer injection port 42, sampling channel 43, interior injection port
41 enter the sampling pool 3, realize sample introduction;After sample introduction, the sampling channel 43 is closed, sample leakage or dirty is prevented
Dye;And by the opening time for controlling the sampling channel 43, it can accurately control sample volume.In addition, passing through the switch
Opening or closing for sampling channel 43 described in 5 active control of component, is not influenced by alimentary canal site environment, can be common to and be appointed
What alimentary canal position, versatility are higher.
It should be appreciated that although this specification is described in terms of embodiments, but not each embodiment only includes one
A independent technical solution, this description of the specification is merely for the sake of clarity, and those skilled in the art should will say
As a whole, the technical solution in each embodiment may also be suitably combined to form those skilled in the art can for bright book
With the other embodiments of understanding.
The series of detailed descriptions listed above only for the application feasible embodiment specifically
Bright, they are not the protection scope to limit the application, all without departing from equivalent implementations made by the application skill spirit
Or change should be included within the scope of protection of this application.
Claims (23)
1. a kind of sampling capsule, including shell, the partition wall in the shell, by the partition wall and positioned at the separation
The shell of the first side of wall encloses the sampling pool for setting and being formed;It is characterized in that, the sampling capsule further include: be set to the separation
Interior injection port on wall, the outer injection port on the shell for being located at described partition wall second side, the connection outer sample introduction
Mouthful with the sampling channel of the interior injection port, open or close the switch block of the sampling channel.
2. sampling capsule according to claim 1, it is characterised in that: enclose and set the wall to form the sampling channel including opposite
The first wall and the second wall being arranged, at least partly described first wall are elastic wall;The switch block forces in the elastic wall,
To adjust the spacing distance between the elastic wall and second wall, so that the elastic wall fits in second wall and closes
The sampling channel opens the sampling channel far from second wall.
3. sampling capsule according to claim 2, it is characterised in that: first wall and second wall are elasticity
Wall, and first wall and second wall are wholely set, the sampling channel are a multi-pass pipe, part nozzle with it is described interior
Injection port connection, other part nozzle are connect with the outer injection port.
4. sampling capsule according to claim 2, it is characterised in that: second wall is arranged close to the partition wall, institute
It states the first wall and is set to the side that the sampling channel deviates from the partition wall.
5. sampling capsule according to claim 2, it is characterised in that: second wall be the partition wall, described first
Wall is to be set to the partition wall and the elastic wall with the spaced elastic wall of the partition wall, the outer injection port
Between, the sampling channel is formed between the elastic wall and the partition wall.
6. according to sampling capsule described in claim 2~5 any one, it is characterised in that: the switch block includes driving
The elastic wall is close to the driving unit of second wall and the control unit of the driving unit communication connection.
7. sampling capsule according to claim 6, it is characterised in that: the driving unit includes logical with described control unit
The micro machine for interrogating connection, the jacking block being connect with the rotor threads of the micro machine;When the rotor rotates, turned by being threadedly engaged
The linear motion of the jacking block is turned to, to force in the elastic wall.
8. sampling capsule according to claim 7, it is characterised in that: the jacking block is not connected with the elastic wall;Or
The jacking block is connected with the elastic wall.
9. sampling capsule according to claim 7, it is characterised in that: the switch block further includes being set to the shell
Inner wall on to limit the sliding rail that the jacking block moves along a straight line.
10. sampling capsule according to claim 6, it is characterised in that: the driving unit includes driving the elastic wall
Close to or far from the mobile driving mechanism of movable block, the driving movable block of the second wall, the driving mechanism includes one end and movement
The marmem and described control unit communication connection that the block connection other end is connect with fixed block are to marmem
Carry out temperature controlled temperature control element;Wherein, when temperature restores threshold value lower than shape, the marmem has the first shape
Shape state, the distance between movable block connection and fixed block are first distance;When temperature is higher than shape recovery threshold value, the shape
Memorial alloy has the second shape state, and the distance between movable block connection and fixed block are second distance, and first distance is less than
Or it is greater than second distance;And biggish distance is configured as in first distance and second distance, movable block forces in the elasticity
Wall makes the elastic wall fit in second wall, closes the sampling channel.
11. sampling capsule according to claim 10, it is characterised in that: the temperature control element is heating element, described the
One distance is greater than the second distance.
12. sampling capsule according to claim 10, it is characterised in that: the temperature control element is cooling element, described the
One distance is less than the second distance.
13. sampling capsule according to claim 10, it is characterised in that: the marmem is set to movable block, consolidates
Determine between block, and two sides opposite with movable block, fixed block are connect respectively at the both ends of the marmem;Or the shape
Memorial alloy be set to movable block, fixed block it is ipsilateral, and the both ends of the marmem respectively with movable block, fixed block court
It is connected to the side of the marmem;Or the marmem is set to ipsilateral, and the institute of movable block, fixed block
The both ends for stating marmem pass through the connector two sides opposite with movable block, fixed block respectively and are connected.
14. sampling capsule according to claim 10, it is characterised in that: one group of movable block and fixed block and a shape are remembered
It is corresponding to recall alloy;Or multiple groups movable block is corresponding with a marmem with fixed block.
15. sampling capsule according to claim 10, it is characterised in that: a marmem and a temperature control element
Corresponding or multiple marmems are corresponding with a temperature control element.
16. sampling capsule according to claim 10, it is characterised in that: the switch block further includes being set to outside described
To limit the auxiliary block that the movable block moves along a straight line on the inner wall of shell.
17. sampling capsule according to claim 6, it is characterised in that: the switch block further include:
With the sensor of described control unit communication connection, the sensor for acquire physiological parameter in the digestive tract and/or
Image information;
With the storage module of described control unit communication connection, the storage module is for storing in alimentary canal different parts just
Physiological parameter and/or image information when normal physiological parameter and/or image information, possible lesion.
18. sampling capsule according to claim 17, it is characterised in that: the sensor is that imaging sensor or pH are passed
At least one of sensor or ultrasonic sensor;When the sensor includes imaging sensor, the part shell is transparent
Shape;When the sensor includes pH sensor, there is window on the shell, pH sensor passes through the window and the digestion
The contact of road liquid.
19. sampling capsule according to claim 17, it is characterised in that: the sampling capsule further include to the external world at
Manage the wireless transport module of terminal called connection.
20. sampling capsule according to claim 1, it is characterised in that: the quantity of the interior injection port is at least two, until
Few two interior injection ports are uniformly distributed or are randomly distributed on the partition wall;The quantity of the outer injection port is at least two
A, at least two outer injection ports are uniformly distributed or are randomly distributed on the shell along the circumferential direction of the shell.
21. sampling capsule according to claim 20, it is characterised in that: the sampling capsule includes that the sampling is logical
Road is connected to all interior injection ports and the outer injection port simultaneously;Or the sampling capsule includes that at least two samplings are logical
Road, the sampling channel are connected at least one described interior injection port and at least one described outer injection port.
22. sampling capsule according to claim 1, it is characterised in that: the sampling capsule further includes being located at the separation
The sample tap being connected on the shell of the first side of wall and with the sampling pool.
23. a kind of sampling capsule system is led to including sampling capsule described in claim 1~22 any one, with switch block
Interrogate the extraneous processing terminal of connection.
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CN201821697788.6U CN209678553U (en) | 2018-10-19 | 2018-10-19 | Sampling capsule and sampling capsule system |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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WO2021218971A1 (en) * | 2020-04-30 | 2021-11-04 | 安翰科技(武汉)股份有限公司 | Sampling/administration capsule |
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2018
- 2018-10-19 CN CN201821697788.6U patent/CN209678553U/en not_active Withdrawn - After Issue
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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WO2021218971A1 (en) * | 2020-04-30 | 2021-11-04 | 安翰科技(武汉)股份有限公司 | Sampling/administration capsule |
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