CN209678485U - Miniature microwave radiometer for temperature anomaly in Non-invasive detection interior tissue - Google Patents
Miniature microwave radiometer for temperature anomaly in Non-invasive detection interior tissue Download PDFInfo
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- CN209678485U CN209678485U CN201690001574.3U CN201690001574U CN209678485U CN 209678485 U CN209678485 U CN 209678485U CN 201690001574 U CN201690001574 U CN 201690001574U CN 209678485 U CN209678485 U CN 209678485U
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- microwave radiometer
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/01—Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01K—MEASURING TEMPERATURE; MEASURING QUANTITY OF HEAT; THERMALLY-SENSITIVE ELEMENTS NOT OTHERWISE PROVIDED FOR
- G01K13/00—Thermometers specially adapted for specific purposes
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- Heart & Thoracic Surgery (AREA)
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- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
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Abstract
The utility model relates to medicine and field of medical device; more particularly to it is a kind of by measuring intrinsic electromagnetic radiation intensity come the radiometric temperature measurement method of Non-invasive detection organism internal tissue temperature exception; more specifically, the present invention relates to a kind of microwave radiometers that its internal tissue temperature is measured during patient's daily routines.The utility model can be used as a part of the diagnostic measures of a set of EARLY RECOGNITION tumor disease, detect the temperature change and heat anomaly of organism interior tissue.The microwave radiometer includes the element of following series connection: for contacting the application type antenna of organism, being switched, circulator, the device of microwave signal amplitude detection and amplification, programmable analog integrated circuit, peltier amplifier, Peltier's element.Furthermore, it is mounted on Peltier's element and first matched load thermally contacting with it is connected to the second input terminal of switch, the counter-jib of circulator is connected to second matched load, and the control output end of programmable analog integrated circuit is connected to the control signal of switch.In addition, the Peltier's element, switch, circulator are all mounted on heat-conducting plate and thermally contact with heat-conducting plate, the switchgear distribution is connected to circulator input terminal at by application type antenna or the first matched load.The microwave radiometer is further equipped with temperature sensor, which is used to measure the temperature of the first matched load and sends data processing and display device for the temperature of measurement.The operating reliability of microwave radiometer will be improved using the utility model.
Description
Technical field
The present invention relates to medicine and field of medical device, that is, are usually directed to based on by measuring its own electromagnetic radiation intensity
Non-invasive detection organism internal tissue temperature exception microwave radiometry technology, more particularly to it is a kind of raw for monitoring patient
Order a kind of microwave radiometer of temperature of interior tissue in active procedure.The present invention can be used for detecting the temperature of organism interior tissue
The equipment of variation and heat anomaly, to identify tumor disease as early as possible.
Background technique
Known medical modulated microwave radiometer has sufficiently large size, therefore they cannot be built into clothes,
The temperature of the interior tissue of people cannot be continuously monitored during his/her vital movement.If this microwave radiometer usually by
Dry unit composition, is mounted on during checking on the special shelf beside patient.
A kind of Compact microwave radiometer known can be used for monitoring inside of human body tissue during his/her vital movement
Internal temperature.(P.Stauffer etc..Application of the microwave radiometry method of non-invasive monitoring temperature in diagnosing and treating
[Utility of Microwave Radiometry for Diagno stic and Therapeutic Applications
Of Non-Invasive Temperature Monitoring] // meeting paper: IEEE BenMAS2014, Philadelphia, DOI:
10.13140/2.1.3762.0487) however, the device is " total power " microwave radiometer, and do not include non-commutative elements.
The measurement error of this microwave radiometer steeply rises with the variation for the input impedance for checking tissue.It is calibrated in inspection area
After instrument, these devices can be used for checking the property that internal tissue temperature changes over time.But due to the input impedance of tissue
In the different significant differences of physical feeling, therefore also will be dramatically different in the brightness temperature of different physical feelings measurement, this causes
The difficulty of the microwave radiometer in actual use when no special calibration at each point.
Therefore, in order to ensure the independence of the dielectric constant measurement result of checked tissue, it is proposed that using there is reflection compensation
The zero balancing radiometer of circuit.
Immediate similar device is a kind of zero balancing medical microwave radiation for Non-invasive detection interior tissue heat anomaly
Meter.(A.V.Weisblat. medical microwave radiometer RTM-01-RES//Biomedetsinskiye tekhnologii i
Radioelektronika.2001.No.8, pp.11-23).This microwave radiometer is by having a size of 342*257*135mm3Letter
The radio sensor composition that breath processing unit (IPU) and inspection Shi doctor hold.The device is by 220V power supply power supply, weight
For 8.5kg.
The radio sensor receives, modulation, filtering, amplifies and detect microwave signal, and amplifies it after sensing, simultaneously
IPU executes synchronous detection, limitation, accumulation, the amplification of the signal exported from synchronizing indicator.Application type antenna is placed directly within object
On body surface face, to receive by the noise signal of the tissue emissions of organism (or people).There is no the case where dissipation loss in antennas
Under, the noise temperature (that is, brightness temperature of biological object) of noise temperature Ta and biological object at antenna output are consistent.The spoke
Penetrate the principle that meter executes sliding noise.
Its operating principle is that modulation passes through the signal of the electronic switch closed or opened.When electronic switch is opened, microwave
The input terminal of the device of the amplification and amplitude detection of signal only receives noise letter from the matched load being mounted on Peltier's element
Number.Peltier's element is controlled by the voltage from peltier amplifier, is heated according to the polarity for the voltage for entering Peltier's element
Or the cooling load, to change the noise from the load input for microwave signal amplification and the device of amplitude detection
The value of signal.When electronic switch closure, the noise signal from antenna output reaches microwave signal amplification and amplitude detection dress
The input terminal set.As a result, synchronizing indicator output end microwave signal amplification and detection after, generate one with come from antenna it is defeated
The proportional voltage of difference between noise signal out and the noise signal from microwave pad output.Amplification and it is necessary
After processing, the signal from synchronizing indicator output is fed to Peltier's element.Feedback loop operation makes from organism
With the signal equalization of microwave pad so that the power of the noise signal from organism and the noise signal from microwave pad
Power is consistent.For microwave pad, the noise power at output is determined by its thermodynamic temperature, therefore, can pass through measurement
Load temperature determines the brightness temperature of organism.
Described scheme provides high-precision measurement.However, the program has the shortcomings that service speed is low, and due to
Huge information process unit, the microwave radiometer can not be used to monitor the temperature during human life activity.
Summary of the invention
The purpose of this technology is to create a kind of miniature (portable) microwave radiometer, with group inside Non-invasive detection with high precision
Temperature anomaly in knitting.
The solution have the advantages that improving the reliability of microwave radiometer when adjusting zero balancing.
On the one hand, a kind of microwave radiometer is provided comprising be connected in series: the application type antenna contacted with organism；
Switch；Circulator, the device of microwave signal amplitude detection and amplification；Field programmable analog array, peltier amplifier；Amber ear
Note element.First matched load is mounted on Peltier's element and thermally contacts with it, and the first matched load is connected to the of switch
Two input terminals, the counter-jib of circulator are connected to the second matched load；The control output end of field programmable analog array connects
To the control signal of switch, wherein peltier-element, switch, circulator are mounted on heat-conducting plate and thermally contact therewith, switch
Adaptability is connected to circulator first input end or application type antenna or the first matched load, wherein microwave radiometer equipped with
Temperature sensor, for measuring the temperature of the first matched load and the temperature of measurement being transmitted to data processing equipment.
In one embodiment, microwave signal amplitude detection and the device of amplification include being connected in series: having band logical filter
Amplifier after the low-noise amplifier of wave device, amplitude detector and detection.
In one embodiment, the second matched load is mounted on heat-conducting plate and thermally contacts with heat-conducting plate.
In one embodiment, the second matched load is mounted on Peltier's element and thermally contacts with it.
In one embodiment, temperature sensor be mounted on Peltier's element or the first matched load on.
In one embodiment, the microwave radiometer further includes microcontroller, wherein temperature sensor and microcontroller
Series connection, the control output end of microcontroller is connected to the control signal of field programmable analog array.
In one embodiment, microcontroller is realized with integrated analog-digital converter or is connected by external analog-digital converter
It is connected to temperature sensor realization.
In one embodiment, the structure of field programmable analog array can be with dynamic configuration.
In one embodiment, field programmable analog array has the structure of static configuration.
In one embodiment, microcontroller be configured as transfer data to data processing equipment.
In one embodiment, microcontroller receives electric power from data processing and instruction device.
In one embodiment, microwave radiometer further includes to switch, microwave signal amplitude detection and the device of amplification, now
Field programmable analog array, peltier amplifier, temperature sensor provide the autonomous power-supply system of electric power.
In one embodiment, microwave radiometer further includes for the dress to switch, microwave signal amplitude detection and amplification
It sets, field programmable analog array, peltier amplifier, temperature sensor, analog-digital converter and microcontroller provide electricity
The autonomous power-supply system of power.
Use site programmable analog array (FPAA) allows to abandon most of outer in static and dynamic and configurable circuit
Department enclosure, which greatly improves the reliabilities of product, greatly reduce cost and size.
Brief Description Of Drawings
Fig. 1 shows one embodiment structure charts of the miniature modulated microwave radiometer proposed according to this technology.
Fig. 2 indicates tool, and there are two the implementations of the miniature modulated microwave radiometer for the microwave pad being mounted on Peltier's element
Example structure chart.
The detailed description of non-limiting embodiment
It is described in detail in Fig. 1 according to the design of miniature (portable) microwave radiometer of this technology.
Microwave radiometer according to this technology includes being connected in series: the application type antenna (3) contacted with organism has
Two input terminals and an output end, the switch (25) of a control signal.Switch one of described two input terminals of (25)
It is connected to antenna (3) output end, second input terminal is connected on the first matched load (9), and the first matched load (9) is mounted on
It thermally contacts on peltier (Peltier) element (10) and therewith.Noise signal from switch (25) output end, which is fed to, to be followed
The input terminal of ring device (26), microwave signal amplification and the device (7) and application type antenna (3) of amplitude detection between offer every
From.
Circulator (26) is operated with valve mode, and counter-jib is equipped with the second matched load (27).Noise signal is from circulator
(26) output end is fed to the device (7) of microwave signal amplification and amplitude detection, has bandpass filtering including series connection
Amplifier after the reactatron of device, amplitude detector and detection.
The device (7) of the input terminal connection microwave signal amplification and amplitude detection of field programmable analog array (FPAA)
Output end, output end are connected to the input terminal of peltier amplifier.
Signal is fed to FPAA (28) from the output end of microwave signal amplification and the device (7) of amplitude detection, wherein institute
Signal is stated with the frequency of 1kHz by filtering, amplification, synchronous detection, accumulation, wherein the amplitude of signal is that dynamic controls.FPAA
(28) control output end is connected to the control signal of switch (25).It switchs (25) and is controlled by FPAA with the frequency of 1kHz, and will
Application type antenna (3) or the first matched load (9) are connected to the input terminal of circulator (26).
Therefore, according to the control signal for coming from FPAA (28), circulator (26) input terminal, which receives, comes from application type antenna Ta
Or come from the first matched load (9) Tr1Noise signal.In FPAA (28) output end, voltage and application type antenna noise temperature Ta
The noise temperature Tr from the first matched load (9) is received in application type antenna output end1Between difference it is proportional.In amber
After ear note amplifier (21), which reaches Peltier's element (21):
Δ U=k (Ta-Tr1),
The amplification coefficient of microwave radiometer RX path in the case that wherein k- opening is fed back,
TaThe noise temperature of application type antenna output,
Tr1The noise temperature of application type antenna output end is come from the first matched load.
According to the polarity of Peltier's element (10) received voltage, thermodynamic temperature changes, to be mounted on it
On the temperature of the first matched load (9) change.This causes defeated after being output to application type antenna from the first matched load (9)
The variation of noise temperature out.Obviously, under feedback effect, the noise temperature T of the first matched load (9)r1Close to from application
The noise temperature T of type antenna (3) output enda。
If application type antenna cannot be coordinated well with organism, the noise signal phase with reflection from organism is measured
The error of the temperature of pass is by the noise signal compensation from the second matched load (27).
In circuit shown in Fig. 1, the second matched load (27) is mounted on heat conducting base and is connected to circulator (26)
Counter-jib.First side of Peltier's element is mounted on heat conducting base and thermally contacts with it with good, while first
The peltier-element opposite with pedestal (10) other side is mounted on load (9) and there is good thermally contact with element.Switch
(25) with circulator (26) also with common heat conducting base have it is good thermally contact, therefore heat conducting base, circulator, switch and
The temperature close of second matched load.
The temperature of first matched load (9) is measured by temperature sensor (11), and temperature sensor (11) may be mounted at amber
There is good thermally contact on ear note element (10) or the first matched load (9) and with them.From temperature sensor (11)
Voltage transmitted by measuring circuit, which is converted into digital form, especially by universal serial bus, then will
It is fed to microcontroller (12) and is transferred to data processing and instruction device.Especially personal computer.
Wherein microcontroller is realized using integrated analog-digital converter, or is connected to temperature by external analog-digital converter and is passed
Sensor.
Microcontroller is configured as transferring data to data processing and instruction device by wired or wireless data link.
Temperature sensor can be configured as the temperature of measurement the first matched load (11), and via wireless data link
Transfer data to data processing and instruction device.
In order to reduce mismatch error, circuit shown in Fig. 2 can be used.In this embodiment, the second matched load (27)
It is mounted on Peltier's element (10) side opposite with heat conducting base and is thermally contacted with it.
In this case, the temperature of the second matched load (27) close to the first matched load (9) temperature, therefore it is close
Biological temperature Ta.Therefore, mismatch error significantly reduces.
The all components part of the microwave radiometer all has common ground potential according to microwave signal.
AN231E04 (Anadigm) QFN-44 microcircuit can be used as FPAA (28).Wherein entire microwave radiometer is placed in one
In a shell, size is no more than 25*30*20mm3, weight is no more than 150g.
It should be noted that received by temperature T at peltier-elementr1And TaBetween difference determine residual voltage, take
Certainly in the value of feedback amplification coefficient.The reduction of feedback amplification coefficient increases the remnants in transient process time and feedback loop accidentally
Difference, this leads to the increase of the thermometric error as caused by the unstability of the amplification coefficient of low-noise amplifier.Feedback loop
The increase of road amplification coefficient can make peltier amplifier overload, this can also run equipment and have a negative impact.
Compared with the conventional synchronization detection circuit realized in prototype circuit, FPAA has static and dynamic configuration structure.
In static programmed circuit, configuration data is loaded when FPAA is connected, and is remained unchanged during its operation.Quiet
In state programmed circuit, when supply voltage is sent to microcircuit, FPAA configuration memory is removed, later configure logic automatically from
Erarable Programmable Read only Memory (EPROM) downloading data.After downloading data, FPAA can activate model configuration automatically.
The circuit of dynamic configuration allows completely or partially to change functional structure in real time in the device of operation.
The configuration interface packet of device (AN220E04, AN221E04, AN221E02 and AN231E04) with dynamic configuration
It includes permission " (on the fly) in online " and downloads the specific function to reset Configuration Data, without reset apparatus.
Dynamic is needed to reconfigure in the application of model configuration during operation, it is necessary to use external microcontroller, this is micro-
Controller allows the new value of counting circuit, these values is collected in configuration data unit, and transmit them to FPAA.
In one embodiment of the invention, FPAA has static configuration structure, the feedback amplification coefficient and band of amplifier
Logical and circuit every other parameter keeps constant during measurement and only changes during processing of circuit.
The dynamic configuration of FPAA provides dynamic and changes feedback control loop amplification coefficient, selective amplifier band logical and delay line
A possibility that constant value of time.The ability for quickly rebuilding all parameters of reception device allows transient process to optimize, this causes to survey
The shortening for measuring the time, to improve device reliability and service speed.
Microwave radiometer can be powered by data processing and instruction device, for example, personal computer.In this case,
Power supply is fed to microcontroller by USB connector.In the case where wireless interface, switch and is put at microwave signal amplitude detection
Big device, field programmable analog array, peltier amplifier, temperature sensor, microcontroller are all by being located at crust of the device
In and be connected to all said elements autonomous power-supply system power supply.
It can be used as the substrate of microstrip line made of Rodgers material with a thickness of 0.2 to 0.5mm dialectical pedestal.This is opened
Pass can be realized on MASW-007107 microcircuit, and peltier amplifier is then in ALM2402-Q1 (TI) DRR-12 microcircuit
Upper realization.3CMM41 circulator can be selected in circulator.
All control signals in microwave radiometer are generated by microcontroller (12).The survey of its output bus reception organism
Measure signal.Microcontroller ensures interaction in software and hardware level of all components of miniature microwave radiometer and really
It protects from the component of miniature microwave radiometer and receives measurement data, necessary processing is carried out to information, be packaged and is transferred to long-range number
According to processing and instruction device.
It is therefore desirable to which the invention of protection will improve the reliability of microwave radiometer and reduce its size, thus patient's
Ensure to measure the ability of the temperature of its interior tissue during vital movement and the device is built into clothes.
The present invention is disclosed by reference to the above specific embodiment.As disclosed herein, its of its essence is not changed
It would have been obvious for a person skilled in the art for his embodiment.It is intended, therefore, that the present invention is only in following right
In the range of it is required that.
Claims (13)
1. a kind of miniature microwave radiometer for temperature anomaly in Non-invasive detection interior tissue, including series connection:
It is application type antenna, switch, circulator, microwave signal amplitude detection and the device of amplification for being contacted with organism, existing
Field programmable analog array, peltier amplifier, Peltier's element,
It is characterized in that, being equipped with the first matched load in the peltier-element, and thermally contacted with the Peltier element, institute
The second input terminal that the first matched load is connected to the switch is stated,
Circulator counter-jib is connected to second matched load,
The control output end of the field programmable analog array is connected to the control signal of the switch,
Wherein, the peltier-element, the switch, the circulator are mounted on heat-conducting plate and thermally contact therewith,
And the switch is configured as the application type antenna or first matched load being connected to the circulator defeated
Enter end,
Wherein, equipped with temperature sensor, which is configured as measuring first matching microwave radiometer
The temperature is simultaneously transferred to data processing and instruction device by the temperature of load.
2. miniature microwave radiometer according to claim 1, which is characterized in that the microwave signal amplitude detection and amplification
Device include amplifier after the low-noise amplifier, bandpass filter, amplitude detector and detection being connected in series.
3. miniature microwave radiometer according to claim 1, which is characterized in that second matched load is mounted on described
It is thermally contacted on heat-conducting plate and with the heat-conducting plate.
4. miniature microwave radiometer according to claim 1, which is characterized in that second matched load is mounted on described
It thermally contacts on Peltier's element and therewith.
5. miniature microwave radiometer according to claim 1, which is characterized in that the temperature sensor is mounted on peltier
On element or on the first matched load.
6. miniature microwave radiometer according to any one of claim 1 to 5, which is characterized in that it further include microcontroller,
The microcontroller and the temperature sensor are connected in series, and its control output end is connected to field programmable analog array
Control signal.
7. miniature microwave radiometer according to claim 6, which is characterized in that the microcontroller is turned with integrated modulus
Parallel operation is realized or is connected to the temperature sensor by external analog-digital converter.
8. miniature microwave radiometer according to claim 7, which is characterized in that the field programmable analog array has
Dynamic configuration structure.
9. miniature microwave radiometer according to any one of claim 1 to 5, which is characterized in that the field-programmable
Analog array has static configuration structure.
10. miniature microwave radiometer according to claim 6, which is characterized in that the microcontroller is configured as to count
According to being transmitted to the data processing equipment.
11. miniature microwave radiometer according to claim 10, which is characterized in that the microcontroller is from the data
Reason and instruction device receive electric power.
12. miniature microwave radiometer according to any one of claim 1 to 5, which is characterized in that further include: Xiang Suoshu
Device, field programmable analog array, peltier amplifier and the temperature sensor of switch, microwave signal amplitude detection and amplification
The autonomous power-supply system of electric power is provided.
13. miniature microwave radiometer according to claim 10, which is characterized in that further include: to the switch, microwave letter
Device, field programmable analog array, peltier amplifier, the temperature sensor, analog-digital converter of number amplitude detection and amplification
The autonomous power-supply system of electric power is provided with microcontroller.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2016135081 | 2016-08-29 | ||
| RU2016135081 | 2016-08-29 | ||
| PCT/RU2016/000697 WO2018044197A1 (en) | 2016-08-29 | 2016-10-13 | Miniature radiometric thermometer for the non-invasive detection of temperature anomalies in internal tissues |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN209678485U true CN209678485U (en) | 2019-11-26 |
Family
ID=61309428
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201690001574.3U Active CN209678485U (en) | 2016-08-29 | 2016-10-13 | Miniature microwave radiometer for temperature anomaly in Non-invasive detection interior tissue |
Country Status (2)
| Country | Link |
|---|---|
| CN (1) | CN209678485U (en) |
| WO (1) | WO2018044197A1 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115003214A (en) * | 2020-01-21 | 2022-09-02 | 大脑温度股份有限公司 | Apparatus and method for non-invasively measuring deep tissue temperature using microwave radiation |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110231516B (en) * | 2019-06-14 | 2021-05-11 | 北京无线电计量测试研究所 | Quick variable temperature microwave noise source |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2082118C1 (en) * | 1994-07-11 | 1997-06-20 | Александр Владимирович Вайсблат | Medicinal radiothermometer |
| GB0207370D0 (en) * | 2002-03-28 | 2002-05-08 | Univ St Andrews | Medical imaging apparatus |
-
2016
- 2016-10-13 WO PCT/RU2016/000697 patent/WO2018044197A1/en active Application Filing
- 2016-10-13 CN CN201690001574.3U patent/CN209678485U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115003214A (en) * | 2020-01-21 | 2022-09-02 | 大脑温度股份有限公司 | Apparatus and method for non-invasively measuring deep tissue temperature using microwave radiation |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2018044197A8 (en) | 2018-07-26 |
| WO2018044197A1 (en) | 2018-03-08 |
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