CN209658133U - For substrate auxiliary laser analysis mass spectrometer ion source device - Google Patents
For substrate auxiliary laser analysis mass spectrometer ion source device Download PDFInfo
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- CN209658133U CN209658133U CN201920413987.8U CN201920413987U CN209658133U CN 209658133 U CN209658133 U CN 209658133U CN 201920413987 U CN201920413987 U CN 201920413987U CN 209658133 U CN209658133 U CN 209658133U
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- mass spectrometer
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Abstract
The utility model discloses one kind to be used for substrate auxiliary laser analysis mass spectrometer ion source device.It includes ion source mechanism, the first cavity, the second cavity, tof tube mechanism and the first chamber lid that this, which is used for substrate auxiliary laser analysis mass spectrometer ion source device,；First cavity has the first accommodating cavity, first cavity has the first accommodating cavity and is connected to the exchange screen of the first accommodating cavity, second cavity has the second accommodating cavity, first cavity is connect with the second cavity and first accommodating cavity is connected to second accommodating cavity, the tof tube mechanism is connected to first cavity and is connected to first accommodating cavity, the ion source mechanism is mounted in first accommodating cavity, the ion source exit tube of the ion source mechanism is towards the tof tube mechanism, first chamber lid and the first cavity detachable connection, first chamber lid is for sealing or opening the exchange screen.This is used for substrate auxiliary laser analysis mass spectrometer ion source device and is convenient for changing ion source mechanism.
Description
Technical field
The utility model relates to mass spectrometer field, more particularly to one kind for substrate auxiliary laser analysis mass spectrometer from
Source arrangement.
Background technique
Matrix-assisted laser desorption ionization instrument is a biomass for being usually used in macromolecular sample analysis
Spectrometer device.When analyzing sample, after so that sample is formed solid on sample target, the sample of Sample Room will be in by lifting device
Target is transmitted on the mobile platform under vacuum state.It will be present initially using the electric field that the combination of pole piece and electric system generates
The ion acceleration of dispersion, focusing, deflection introduce field-free flight area, are sequentially sent to inspection after the ion of different quality is separated
It surveys in device and is detected.Among these, if ion source module is packed into decentraction or position in ion source chamber body and shifts all
Meeting generates very big influence to the performance of instrument.So it is very important for the installation and replacement of ion source, traditional ion
The substitute mode in source is to dismantle tool housing, and vacuum line and route pull out, and opens instrument chamber lid and tears ion source open from bottom
It is lower replacement or tof tube is dismantled, from above ion source is integrally taken out, either take out from top to bottom or from the bottom up from
Component is all very inconvenient, it is necessary to instrument broken, the replacing construction and cost of labor of after-sales staff are considerably increased, and
And instrument tear open it is more scattered, it is easier increase instrument gas leakage risk, cause vacuum not up to standard.
Utility model content
Based on this, it is necessary to provide that a kind of replacement of ion source mechanism is convenient and replacement section time power swashs for Matrix-assisted
Mass spectrometer ion source device is analysed in photodissociation.
One kind being used for substrate auxiliary laser analysis mass spectrometer ion source device, including ion source mechanism, the first cavity, second
Cavity, tof tube mechanism and the first chamber lid；First cavity has the first accommodating cavity and is connected to first accommodating
The exchange screen of chamber, second cavity have the second accommodating cavity, and first cavity is connect and described with second cavity
First accommodating cavity is connected to second accommodating cavity, and the tof tube mechanism is connected to first cavity and holds with described first
Chamber connection is set, the ion source mechanism is mounted in first accommodating cavity, the ion source exit tube court of the ion source mechanism
To the tof tube mechanism, first chamber lid and the first cavity detachable connection, first chamber lid is for sealing
Or open the exchange screen.
First cavity has the first accommodating cavity and is connected to first accommodating cavity in one of the embodiments,
Flight interface tube, the tof tube mechanism and the tof tube orifice.
It in one of the embodiments, further include the first fastener, first fastener can be with first cavity
Removable connection, when first chamber lid is connect with first cavity, first fastener is used for first chamber
Lid is fastenedly connected with first cavity.
First fastener is fastening screw in one of the embodiments, and first chamber lid is equipped with fastener hole,
First cavity is equipped with binding groove, and when first chamber lid is connect with first cavity, first fastener is worn
Set on the fastener hole and the binding groove to be fastened to first chamber lid and first cavity, first fastener
It is threadedly coupled with the fastener hole, the binding groove.
It in one of the embodiments, further include sealing ring, the sealing ring is located in first chamber lid, when described
When one chamber lid is connect with first cavity, the sealing ring is between first chamber lid and first cavity.
It in one of the embodiments, further include the second chamber lid, second cavity has cavity hatch, second chamber
Lid is connected on second cavity and seals the cavity hatch, and second chamber lid is equipped with chamber lid hole, first chamber
Body is connected in second chamber lid, and first accommodating cavity is connected to the chamber lid hole.
Second chamber lid and the second cavity detachable connection in one of the embodiments,.
First cavity and the second chamber lid detachable connection in one of the embodiments,.
The tof tube mechanism and the first cavity detachable connection in one of the embodiments,.
The inner wall of first accommodating cavity is equipped with for for ion source mechanism positioning in one of the embodiments,
Locating piece.
It in one of the embodiments, further include the second fastener, the ion source mechanism and the locating piece pass through institute
The second fastener is stated to be fastenedly connected.
It is convenient that the above-mentioned ion source mechanism for substrate auxiliary laser analysis mass spectrometer ion source device is replaced, replacing construction
It is short, it can achieve the purpose that save time power, cost of labor is effectively reduced.The utility model is used for Matrix Assisted Laser Desorption matter
Spectrometer ion source device is when carrying out the replacement of ion source mechanism, it is only necessary to the first chamber lid is dismantled, without to other vacuums
Part is disassembled, and the time cost of technical staff's replacement after sale is greatly saved, meanwhile, also reduce replacement ion source mechanism
In addition difficulty also largely keeps multiple vacuum components to be in installation condition, reduce and be used for Matrix Assisted Laser Desorption matter
The probability of the gas leakage of spectrometer ion source device reduces the risk of bring gas leakage due to replacing ion source mechanism, so that instrument
Service performance is stablized.
Detailed description of the invention
Fig. 1 is that substrate auxiliary laser analysis mass spectrometer ion source device perspective view of the explosion is used for described in an embodiment；
Fig. 2 is the first cavity and ion source shown in FIG. 1 for substrate auxiliary laser analysis mass spectrometer ion source device
Mechanism mounting structure schematic diagram；
Fig. 3 is the first cavity shown in Fig. 2 and ion source mechanism mounting structure side schematic view；
Fig. 4 is the first cavity shown in Fig. 2 and ion source mechanism mounting structure side cross sectional views.
Description of symbols
10: being used for substrate auxiliary laser analysis mass spectrometer ion source device；100: ion source mechanism；200: the first cavitys；
210: prominent side；211: through-hole；220: binding groove；230: cavity threaded hole；240: exchange screen；250: locating piece；300: the
Two cavitys；400: tof tube mechanism；500: the first chamber lids；510: fastener hole；600: the second chamber lids；610: chamber lid threaded hole；
620: cavity hatch；710: the first fasteners；720: the second fasteners；800: sealing ring；900: connection ring；910: connecting hole.
Specific embodiment
The utility model is more fully retouched below with reference to relevant drawings for the ease of understanding the utility model,
It states.The preferred embodiment of the utility model is given in attached drawing.But the utility model can come in many different forms in fact
It is existing, however it is not limited to embodiment described herein.On the contrary, purpose of providing these embodiments is makes public affairs to the utility model
The understanding for opening content is more thorough and comprehensive.
It should be noted that it can be directly anchored to another yuan when element is referred to as " being fixed on " another element
On part or there may also be elements placed in the middle.When an element is considered as " connection " another element, it be can be directly
It is connected to another element or may be simultaneously present centering elements.When an element is considered as " being mounted on " another yuan
Part, it, which can be, is directly installed on another element or may be simultaneously present centering elements.When an element is considered as " setting
" another element, it, which can be, is directly arranged in another element or may be simultaneously present centering elements.
Unless otherwise defined, all technical and scientific terms used herein are led with the technology for belonging to the utility model
The normally understood meaning of the technical staff in domain is identical.Terminology used in the description of the utility model herein only be
The purpose of description specific embodiment, it is not intended that in limitation the utility model.Term as used herein "and/or" includes
Any and all combinations of one or more related listed items.
It is shown in Figure 1, an embodiment of the present invention provide it is a kind of for substrate auxiliary laser analysis mass spectrometer from
Source arrangement 10.It includes ion source mechanism 100, the first cavity that this, which is used for substrate auxiliary laser analysis mass spectrometer ion source device 10,
200, the second cavity 300, tof tube mechanism 400 and the first chamber lid 500.
First cavity 200 has the first accommodating cavity and is connected to the exchange screen 240 of the first accommodating cavity.Second cavity
300 have the second accommodating cavity.First cavity 200 is connect with the second cavity 300 and the first accommodating cavity is connected to the second accommodating cavity.
Tof tube mechanism 400 is connected to the first cavity 200 and is connected to the first accommodating cavity.
Shown in Figure 2, ion source mechanism 100 is mounted in the first accommodating cavity, the ion source outgoing of ion source mechanism 100
Pipe is towards tof tube mechanism 400.
200 detachable connection of first chamber lid 500 and the first cavity, the first chamber lid 500 is for sealing or opening replacement
Window 240.
In a specific example, the first cavity 200 has the first accommodating cavity and is connected to the tof tube of the first accommodating cavity
Interface, tof tube mechanism 400 and tof tube orifice.
In a specific example, the above-mentioned substrate auxiliary laser analysis mass spectrometer ion source device 10 that is used for further includes first tight
Firmware 710.First fastener 710 can with the removable connection of the first cavity 200, when the first chamber lid 500 and the first cavity 200 connect
When connecing, the first fastener 710 is for the first chamber lid 500 and the first cavity 200 to be fastenedly connected.
Shown in Figure 1, further, the first fastener 710 is fastening screw.First chamber lid 500 is equipped with fastener hole
510, the first cavity 200 is equipped with binding groove 220, when the first chamber lid 500 is connect with the first cavity 200, the first fastener 710
Fastener hole 510 and binding groove 220 are arranged in to the first chamber lid 500 and the fastening of the first cavity 200, the first fastener 710 with
Fastener hole 510, binding groove 220 are threadedly coupled.
In a specific example, the above-mentioned substrate auxiliary laser analysis mass spectrometer ion source device 10 that is used for further includes sealing ring
800.Sealing ring 800 in a ring, the shape adaptation of the shape of sealing ring 800 and the first chamber lid 500.Sealing ring 800 is located at first
In chamber lid 500, when the first chamber lid 500 is connect with the first cavity 200, sealing ring 800 is located at the first chamber lid 500 and the first cavity
Between 200.
Shown in Figure 1, optionally, above-mentioned for substrate auxiliary laser analysis mass spectrometer ion source device 10 further includes the
Two chamber lids 600.Second cavity 300 has cavity hatch 620.Second chamber lid 600 is connected on the second cavity 300 and seal cavity
Opening 620, the second chamber lid 600 are equipped with chamber lid hole, and the first cavity 200 is connected in the second chamber lid 600, the first accommodating cavity and chamber
Cap bore connection.
Further, position shown in Figure 1, cavity hatch 620 are located at the top of the second cavity 300, the second chamber lid
600 are connected to the top of the second cavity 300.First cavity 200 is mounted in the second chamber lid 600, and exchange screen 240 is located at first
One of side of cavity 200, tof tube mechanism 400 are connected to the top of the first cavity 200.
In a specific example, 300 detachable connection of the second chamber lid 600 and the second cavity.For example, the second chamber lid 600
Edge such as vertex and 620 edge of cavity hatch of the second cavity 300 can be bolted by multiple.
Preferably, 600 detachable connection of the first cavity 200 and the second chamber lid.For example, the first cavity 200 is by multiple
Bolt is connect with the second chamber lid 600.Preferably, the bottom of the first cavity 200 protrudes multiple prominent sides 210, each prominent side
There is through-hole 211, the second chamber lid 600 is equipped with multiple chamber lid threaded holes 610, when the first cavity 200 and the second chamber lid on 210
When 600 connection, corresponding through-hole 211 is worn by above-mentioned bolt and is fastenedly connected with chamber lid threaded hole 610.
Preferably, 200 detachable connection of tof tube mechanism 400 and the first cavity.For example, tof tube mechanism 400 passes through
Multiple bolts are connect with the first cavity 200.Preferably, the bottom of tof tube mechanism 400 is connected with the connection ring 900 of annular, even
Ring 900 is connect equipped with multiple connecting holes 910, the first cavity 200 is equipped with multiple cavities threaded hole 230, when tof tube mechanism 400
When being connect with the first cavity 200, corresponding connecting hole 910 is worn by above-mentioned bolt and is fastened with cavity threaded hole 230
Connection.
In a specific example, the inner wall of the first accommodating cavity is equipped with the locating piece for positioning for ion source mechanism 100
250。
Further, the above-mentioned substrate auxiliary laser analysis mass spectrometer ion source device 10 that is used for further includes the second fastener
720.Ion source mechanism 100 is fastenedly connected with locating piece 250 by the second fastener 720.
It is shown in Figure 1, further, the cylindrical circular tubulose of tof tube mechanism 400.It is understood that in other embodiments
In, the structure and shape of tof tube mechanism 400 are not limited to above, and the structure and shape of tof tube mechanism 400 can also be rectangular
Tubulose.
It is above-mentioned for substrate auxiliary laser analysis mass spectrometer ion source device 10 when replacing ion source mechanism 100, including
Following steps:
The first fastener 710 is dismantled, the first chamber lid 500 is removed from the first cavity 200, more from the first cavity 200
The second fastener 720 of disassembly at window 240 is changed, so that ion source mechanism 100 and locating piece 250 are dismantled, from exchange screen 240
Take out ion source mechanism 100.
New ion source mechanism 100 is taken, the bottom of ion source mechanism 100 is first put into the first appearance by exchange screen 240
It sets intracavitary, gradually send the bottom of ion source mechanism 100 to the second accommodating cavity, ion source mechanism 100 can be put into completely at this time
In first accommodating cavity, the position of ion source mechanism 100 is ajusted, so that ion source mechanism 100 contacts locating piece 250, referring to fig. 2-
Shown in Fig. 4, the axis collinear of the axis of ion source mechanism 100 and tof tube mechanism 400, solid by the second fastener 720 at this time
Determine ion source mechanism 100 and locating piece 250.
First chamber lid 500 is covered at exchange screen 240, the first chamber lid 500 and first is fastened by the first fastener 710
Cavity 200 completes the replacement of ion source mechanism 100.
It is convenient that the above-mentioned ion source mechanism 100 for substrate auxiliary laser analysis mass spectrometer ion source device 10 is replaced, more
It is short to change the time, can achieve the purpose that save time power, cost of labor is effectively reduced.The utility model is used for ground substance assistant laser
Mass spectrometer ion source device 10 is parsed when carrying out the replacement of ion source mechanism 100, it is only necessary to dismantle the first chamber lid 500, nothing
Other vacuum components need to be disassembled, the time cost of technical staff's replacement after sale is greatly saved, meanwhile, it also reduces more
The difficulty of ion source mechanism 100 is changed, multiple vacuum components is in addition also largely kept to be in installation condition, reduces and is used for base
The probability of the gas leakage of matter Assisted Laser Desorption mass spectrometer ion source device 10 is reduced because replacing ion source mechanism 100 due to bring
The risk of gas leakage, so that the service performance of instrument is stablized.
Each technical characteristic of embodiment described above can be combined arbitrarily, for simplicity of description, not to above-mentioned reality
It applies all possible combination of each technical characteristic in example to be all described, as long as however, the combination of these technical characteristics is not deposited
In contradiction, all should be considered as described in this specification.
Above-described embodiments merely represent several embodiments of the utility model, the description thereof is more specific and detailed,
But it should not be understood as limiting the scope of the patent of the utility model.It should be pointed out that for the common of this field
For technical staff, without departing from the concept of the premise utility, various modifications and improvements can be made, these all belong to
In the protection scope of the utility model.Therefore, the scope of protection shall be subject to the appended claims for the utility model patent.
Claims (10)
1. one kind is used for substrate auxiliary laser analysis mass spectrometer ion source device, which is characterized in that including ion source mechanism, first
Cavity, the second cavity, tof tube mechanism and the first chamber lid；First cavity has the first accommodating cavity and is connected to described
The exchange screen of first accommodating cavity, second cavity have the second accommodating cavity, and first cavity and second cavity connect
Connect and first accommodating cavity be connected to second accommodating cavity, the tof tube mechanism be connected to first cavity and with institute
The connection of the first accommodating cavity is stated, the ion source mechanism is mounted in first accommodating cavity, the ion source of the ion source mechanism
Exit tube is towards the tof tube mechanism, first chamber lid and the first cavity detachable connection, first chamber lid
For sealing or opening the exchange screen.
2. according to claim 1 be used for substrate auxiliary laser analysis mass spectrometer ion source device, which is characterized in that described
First cavity has the first accommodating cavity and is connected to the flight interface tube of first accommodating cavity, the tof tube mechanism and institute
State tof tube orifice.
3. according to claim 1 be used for substrate auxiliary laser analysis mass spectrometer ion source device, which is characterized in that also wrap
Include the first fastener, first fastener can with the removable connection of the first cavity, when first chamber lid with it is described
When first cavity connects, first fastener is for first chamber lid and first cavity to be fastenedly connected.
4. according to claim 3 be used for substrate auxiliary laser analysis mass spectrometer ion source device, which is characterized in that described
First fastener is fastening screw, and first chamber lid is equipped with fastener hole, and first cavity is equipped with binding groove, when described
When first chamber lid is connect with first cavity, first fastener is arranged in the fastener hole and the binding groove with right
First chamber lid and first cavity fasten, and first fastener and the equal screw thread of the fastener hole, the binding groove connect
It connects.
5. according to any one of claims 1-4 be used for substrate auxiliary laser analysis mass spectrometer ion source device, spy
Sign is, further includes sealing ring, and the sealing ring is located in first chamber lid, when first chamber lid and first cavity
When connection, the sealing ring is between first chamber lid and first cavity.
6. according to any one of claims 1-4 be used for substrate auxiliary laser analysis mass spectrometer ion source device, spy
Sign is, further includes the second chamber lid, and second cavity has cavity hatch, and second chamber lid is connected to second cavity
Above and the cavity hatch is sealed, second chamber lid is equipped with chamber lid hole, and first cavity is connected to second chamber lid
On, first accommodating cavity is connected to the chamber lid hole.
7. according to claim 6 be used for substrate auxiliary laser analysis mass spectrometer ion source device, which is characterized in that described
Second chamber lid and the second cavity detachable connection.
8. according to claim 6 be used for substrate auxiliary laser analysis mass spectrometer ion source device, which is characterized in that described
First cavity and the second chamber lid detachable connection.
9. according to any one of claims 1-4 be used for substrate auxiliary laser analysis mass spectrometer ion source device, spy
Sign is, the tof tube mechanism and the first cavity detachable connection.
10. according to any one of claims 1-4 be used for substrate auxiliary laser analysis mass spectrometer ion source device, spy
Sign is that the inner wall of first accommodating cavity is equipped with for the locating piece for ion source mechanism positioning.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920413987.8U CN209658133U (en) | 2019-03-29 | 2019-03-29 | For substrate auxiliary laser analysis mass spectrometer ion source device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920413987.8U CN209658133U (en) | 2019-03-29 | 2019-03-29 | For substrate auxiliary laser analysis mass spectrometer ion source device |
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| CN209658133U true CN209658133U (en) | 2019-11-19 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201920413987.8U Active CN209658133U (en) | 2019-03-29 | 2019-03-29 | For substrate auxiliary laser analysis mass spectrometer ion source device |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113745090A (en) * | 2021-09-15 | 2021-12-03 | 深圳泰莱生物科技有限公司 | Processing and analyzing system and method of mass spectrum device |
| WO2023207159A1 (en) * | 2022-04-29 | 2023-11-02 | 中元汇吉生物技术股份有限公司 | Ion source cavity, ion source, and mass spectrometer |
-
2019
- 2019-03-29 CN CN201920413987.8U patent/CN209658133U/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113745090A (en) * | 2021-09-15 | 2021-12-03 | 深圳泰莱生物科技有限公司 | Processing and analyzing system and method of mass spectrum device |
| WO2023207159A1 (en) * | 2022-04-29 | 2023-11-02 | 中元汇吉生物技术股份有限公司 | Ion source cavity, ion source, and mass spectrometer |
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Address after: 510535 building 501, No. 1, No. 16, Xinrui Road, Huangpu District, Guangzhou, Guangdong Province (office only) Patentee after: GUANGZHOU HEXIN KANGYUAN MEDICAL TECHNOLOGY CO.,LTD. Address before: 510700 3 / F, building A3, science and technology enterprise accelerator, 11 Kaiyuan Avenue, Huangpu District, Guangzhou City, Guangdong Province Patentee before: GUANGZHOU HEXIN KANGYUAN MEDICAL TECHNOLOGY CO.,LTD. |