CN209656673U - A kind of agitating device for dissolution rate test instrument - Google Patents
A kind of agitating device for dissolution rate test instrument Download PDFInfo
- Publication number
- CN209656673U CN209656673U CN201920426832.8U CN201920426832U CN209656673U CN 209656673 U CN209656673 U CN 209656673U CN 201920426832 U CN201920426832 U CN 201920426832U CN 209656673 U CN209656673 U CN 209656673U
- Authority
- CN
- China
- Prior art keywords
- stripping rotor
- flabellum
- gear
- stirring rod
- cup
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000004090 dissolution Methods 0.000 title claims abstract description 15
- 238000012360 testing method Methods 0.000 title claims abstract description 15
- 238000003756 stirring Methods 0.000 claims abstract description 39
- 241000883990 Flabellum Species 0.000 claims abstract description 28
- NJPPVKZQTLUDBO-UHFFFAOYSA-N novaluron Chemical compound C1=C(Cl)C(OC(F)(F)C(OC(F)(F)F)F)=CC=C1NC(=O)NC(=O)C1=C(F)C=CC=C1F NJPPVKZQTLUDBO-UHFFFAOYSA-N 0.000 claims abstract description 10
- 239000012530 fluid Substances 0.000 claims abstract description 4
- 238000000034 method Methods 0.000 abstract description 9
- 239000002904 solvent Substances 0.000 abstract description 9
- 230000000694 effects Effects 0.000 abstract description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract description 5
- 230000009286 beneficial effect Effects 0.000 abstract description 3
- 239000003814 drug Substances 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 101100327917 Caenorhabditis elegans chup-1 gene Proteins 0.000 description 1
- 229960000074 biopharmaceutical Drugs 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000007922 dissolution test Methods 0.000 description 1
- 238000003255 drug test Methods 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 238000004088 simulation Methods 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
Abstract
The utility model provides the agitating device that a kind of field of biological pharmacy is used for dissolution rate test instrument, including stripping rotor, the stirring rod being detachably connected with head, it further include the pedestal with the cup lid of stripping rotor opening cooperation and for placing stripping rotor, stripping rotor can be rotated relative to pedestal；Axially disposed on the stirring rod to have several groups flabellum, the rotating diameter of the flabellum, which is from top to bottom gradually increased, makes the tapered distribution of flabellum, and the rotation direction of the flabellum makes that the fluid in stripping rotor is pushed to flow to bottom of a cup when flabellum rotates；The bottom of a cup of the stripping rotor is provided with tapered shunting block, the axis of the tip face stirring rod of the tapered shunting block.The utility model has the beneficial effects that being not in the eddies of water in whipping process, solvent can realize convection current up and down in whipping process, stir evenly that stirring efficiency and effect are preferable, easy to operate, easy to use.
Description
Technical field
The utility model relates to bio-pharmaceuticals dissolution rate test instrument technical fields, in particular to a kind of to survey for dissolution rate
Try the agitating device of instrument.
Background technique
At present when drug test, need to detect using dissolution rate test instrument defined solvent and under the conditions of, drug is from piece
The speed and degree dissolved out in the solid pharmaceutical preparations such as agent, capsule, granule, i.e. Dissolution Rate Testing (Dissolution test),
It is the in vitro test method of a kind of disintegration in the gastrointestinal tract of simulation oral solid formulation and dissolution.Carrying out Dissolution Rate Testing
When, it needs to be stirred the drug placed in a solvent, the agitating device of dissolution rate test instrument is by one in the prior art
Tool is placed in stripping rotor there are two the stirring-head of blade and is stirred, and this single blade agitating device can make to dissolve out in stirring
Solvent in cup forms the eddies of water, and the range stirred is smaller, and solvent cannot form flowing up and down, and stirring is uneven, and effect is bad,
Stirring efficiency is low.
Utility model content
The purpose of the utility model is to provide a kind of agitating devices for dissolution rate test instrument, to solve above-mentioned background skill
The problem of being proposed in art.
In order to achieve the above object, the utility model is achieved by the following technical programs: one kind being used for dissolution rate test
The agitating device of instrument further includes the cup lid with stripping rotor opening cooperation including stripping rotor, the stirring rod being detachably connected with head
With the pedestal for placing stripping rotor, the through-hole with stirring rod cooperation is provided on the cup lid, the lower end of stirring rod passes through cup
It is placed in stripping rotor；Bearing is provided on the pedestal, stripping rotor can be rotated relative to pedestal；The stirring rod is located at cup
It covers on the position of lower section and is socketed with first gear, second gear, first tooth are connected with by shaft on the cup lid inner wall
Wheel is engaged with second gear, and the stripping rotor, which is located on the inner wall of opening, is arranged rack gear, the gear ring inner wall and the second tooth
Wheel engagement, the first gear, second gear and gear ring are located in same horizontal line；It is axially disposed on the stirring rod to have
Several groups flabellum, the rotating diameter of the flabellum, which is from top to bottom gradually increased, makes the tapered distribution of flabellum, the rotation direction of the flabellum
Make that the fluid in stripping rotor is pushed to flow to bottom of a cup when flabellum rotates；The bottom of a cup of the stripping rotor is provided with tapered shunting
Block, the axis of the tip face stirring rod of the tapered shunting block.
Further, there are several protrusions on the inner wall of the stripping rotor.
The utility model has the beneficial effects that being not in the eddies of water in whipping process, solvent is on whipping process can be realized
Lower convection current, stirs evenly, and stirring efficiency and effect are preferable, easy to operate, easy to use.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of the utility model.
Specific embodiment
The utility model is described in detail below with reference to attached drawing:
As shown in Figure 1:
A kind of agitating device for dissolution rate test instrument, the stirring rod 2 being detachably connected including stripping rotor 1, with head,
Further include the pedestal 4 with the cup lid 3 of the opening cooperation of stripping rotor 1 and for placing stripping rotor 1, is provided with and stirs on the cup lid 3
The through-hole of the cooperation of bar 2 is mixed, the lower end of stirring rod 2 passes through cup lid 3 and is placed in stripping rotor 1；It is provided with bearing on the pedestal 4, it is molten
Cup 1 can be rotated relative to pedestal 4 out；The stirring rod 2, which is located on the position of 3 lower section of cup lid, is socketed with first gear 5, described
Second gear 6 is connected with by shaft on 3 inner wall of cup lid, the first gear 5 is engaged with second gear 6, the stripping rotor 1
In rack gear 7 is arranged on the inner wall of opening, 7 inner wall of gear ring is engaged with second gear 6, the first gear 5, the second tooth
Wheel 6 and gear ring 7 are located in same horizontal line；It is axially disposed on the stirring rod 2 to have several groups flabellum 8, the flabellum 8
Rotating diameter, which is from top to bottom gradually increased, makes the tapered distribution of flabellum 8, and the rotation direction of the flabellum 8 makes the promotion when flabellum 8 rotates
Fluid in stripping rotor 1 is flowed to bottom of a cup；The bottom of a cup of the stripping rotor 1 is provided with tapered shunting block 9, the tapered shunting block
The axis of 9 tip face stirring rod 2.
Have several raised 10 on the inner wall of the stripping rotor 1.
In use, motor head drives flabellum 8 to rotate by stirring rod 2, first gear 5 and stirring rod 2 are rotated synchronously, and
Drive the equidirectional rotation of second gear 6, second gear 6 engage with gear ring 7, this in the process the drive stripping rotor 1 of gear ring 7 to stirring
The opposite direction rotation of 2 rotation direction of bar, the course of work realize stirring of the flabellum to test sample, meanwhile, in stripping rotor 1
Protrusion 10 on wall is rotated backward and is stirred with flabellum, so that the stirring of test sample is more full and uniform, improves stirring effect
Rate；Meanwhile in the rotation process of flabellum 8, due to the tapered distribution from top to bottom of multiple groups flabellum 8, solvent is in multiple groups flabellum 8
It gradually pushes down on down, using the tapered shunting block 9 of 1 bottom of a cup of stripping rotor, so that it is adequately right to be dissolved in realization in stripping rotor 1
Stream, it is further to improve stirring efficiency and mixing effect, due to the conical distribution structure of multiple groups flabellum 8, it is located at 2 top of stirring rod
8 rotating diameter of flabellum it is smaller, the convection action of solvent is larger in addition, therefore is less prone to the eddies of water, stir it is more abundant.
The utility model has the beneficial effects that being not in the eddies of water in whipping process, solvent is on whipping process can be realized
Lower convection current, stirs evenly, and stirring efficiency and effect are preferable, easy to operate, easy to use.
Above embodiments are merely intended for describing the technical solutions of the present application, but not for limiting the present application, although referring to preferred embodiment pair
The utility model is described in detail, those skilled in the art should understand that, it can be to the technology of the utility model
Scheme is modified or replaced equivalently, and without departing from the objective and range of technical solutions of the utility model, should all be covered
In the scope of the claims of the utility model.
Claims (2)
1. a kind of agitating device for dissolution rate test instrument is also wrapped including stripping rotor, the stirring rod being detachably connected with head
Include with the cup lid of stripping rotor opening cooperation and pedestal for placing stripping rotor, be provided on the cup lid and stirring rod cooperation
Through-hole, the lower end of stirring rod pass through cup lid and are placed in stripping rotor；Bearing is provided on the pedestal, stripping rotor can be the bottom of relative to
Seat rotation；The stirring rod, which is located on the position below cup lid, is socketed with first gear, is connected on the cup lid inner wall by shaft
Be connected to second gear, the first gear is engaged with second gear, the stripping rotor be located on the inner wall of opening be arranged it is with teeth
Circle, the gear ring inner wall are engaged with second gear, and the first gear, second gear and gear ring are located in same horizontal line；Its
Be characterized in that: axially disposed on the stirring rod to have a several groups flabellum, the rotating diameter of the flabellum is from top to bottom gradually
Increase makes the tapered distribution of flabellum, and the rotation direction of the flabellum makes to push the fluid in stripping rotor to bottom of a cup stream when flabellum rotates
It is dynamic；The bottom of a cup of the stripping rotor is provided with tapered shunting block, the axis of the tip face stirring rod of the tapered shunting block.
2. a kind of agitating device for dissolution rate test instrument according to claim 1, it is characterised in that: the stripping rotor
Inner wall on have several protrusions.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920426832.8U CN209656673U (en) | 2019-03-30 | 2019-03-30 | A kind of agitating device for dissolution rate test instrument |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920426832.8U CN209656673U (en) | 2019-03-30 | 2019-03-30 | A kind of agitating device for dissolution rate test instrument |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN209656673U true CN209656673U (en) | 2019-11-19 |
Family
ID=68528483
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201920426832.8U Expired - Fee Related CN209656673U (en) | 2019-03-30 | 2019-03-30 | A kind of agitating device for dissolution rate test instrument |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN209656673U (en) |
-
2019
- 2019-03-30 CN CN201920426832.8U patent/CN209656673U/en not_active Expired - Fee Related
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20191119 |