CN209619367U - Anti-tumor experiment tumor cell culture device - Google Patents
Anti-tumor experiment tumor cell culture device Download PDFInfo
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- CN209619367U CN209619367U CN201920190610.0U CN201920190610U CN209619367U CN 209619367 U CN209619367 U CN 209619367U CN 201920190610 U CN201920190610 U CN 201920190610U CN 209619367 U CN209619367 U CN 209619367U
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Abstract
The utility model discloses a kind of anti-tumor experiment tumor cell culture devices, are related to technical field of cell culture comprising the lower surface of incubator, the culture chamber interior wall is connected with first bearing, and first rotating shaft is socketed in first bearing.Anti-tumor experiment tumor cell culture device, pass through regulating device, driving wheel, driven wheel, belt, sliding block, threaded post, the mutual cooperation of drive roll and driven voller, fixed block drives drive roll to be rotated, to drive culture bottle to be rotated, cell is set to carry out adhere-wall culture, it realizes adherent suspension and cultivates two-in-one function, regulating device drives the second shaft and threaded post rotation, since the position of threaded post is fixed, to make thread barrel drive two sliding blocks close to each other or separate under the action of being threaded in threaded post, realize the adjusting of the distance between driven voller and drive roll, it is rotated suitable for culture bottle of different sizes, improve the practicability of culture apparatus.
Description
Technical field
The utility model relates to technical field of cell culture, specially a kind of anti-tumor experiment is filled with tumor cell culture
It sets.
Background technique
It is well known that tumor cell culture is to carry out basis and the guarantee of a series of oncology experiments, only using growth
Cell in good condition could show true and reliable result in subsequent experimentation.Cell culture can be most common at last
Experiment, but to have raised the cell not a duck soup of state.There are many factor for influencing cell growth, any one link
Going wrong can all make experimentation have difficulty in taking a step, and cause the waste of time and economic cost.
Red blood-cell cultivation rotating-bottle machine is called cell culture roller bottle machine, is numerous in simulation cell growth conditions carry out greatly in vitro
It grows, and obtains the instrument of required normal cell and development & production, the skill of the aspect in culture is generally indicated with rolling bottle number
Art index, is biologic medical, R&D institution, and colleges and universities etc. are used to cultivate the optimal selection of cell, is divided into suspension cell culture rolling bottle
Machine, attached cell cultivate Rotary Machine etc..
But the position between existing red blood-cell cultivation rotating-bottle machine drive roll and driven voller is fixed and invariable, single distance
Only fix specification culture bottle rotated, can not for culture bottle size to the distance between drive roll and driven voller into
Row is adjusted, and is made red blood-cell cultivation rotating-bottle machine there are biggish limitation, is reduced the practicability in Cultural Course of Tumor Cells.
Utility model content
(1) the technical issues of solving
In view of the deficiencies of the prior art, the utility model provides a kind of anti-tumor experiment tumor cell culture device,
The position solved between existing red blood-cell cultivation rotating-bottle machine drive roll and driven voller is fixed and invariable, and can not be directed to culture bottle
Size the distance between drive roll and driven voller are adjusted, make red blood-cell cultivation rotating-bottle machine there are biggish limitation, drop
In low Cultural Course of Tumor Cells the problem of practicability.
(2) technical solution
To achieve the above objectives, the technical scheme adopted by the utility model is that: a kind of anti-tumor experiment is trained with tumour cell
Device, including incubator are supported, the lower surface of the culture chamber interior wall is connected with first bearing, and first is socketed in first bearing
Shaft, and the top of first rotating shaft is fixedly connected by drive roll with the lower surface of driving device, the upper table of the driving device
Face is fixedly connected with the upper surface of culture chamber interior wall, and the upper and lower surfaces for cultivating chamber interior wall are opened up there are two sliding slot,
And sliding block is slidably connected in sliding slot.
The left side of the sliding block is connected by thread barrel and the outer surface thread of threaded post, and the threaded post phase of top two
Separate one end is fixedly connected to the second shaft, and two mutually separate one end of the second shaft are socketed with second bearing, and two
A second bearing is connected to the inner wall of sliding slot.
The left and right side of the drive roll is provided with driven voller, and the both ends of two driven vollers respectively with two first
One end of shaft opposite face is fixedly connected, and two first rotating shafts are socketed with first bearing, and two first bearings are blocked respectively
The opposite face in two sliding blocks is connect, and the right end of two the second shafts of right side is fixedly connected to driven wheel, and two driven wheels
Outer surface and the inner surface of belt overlap, and two driven wheels are sequentially connected by the outer surface of belt and driving wheel, described
Driving wheel is fixedly connected on the outer surface of regulating device, and the left side of regulating device is connected to the right side of incubator.
Preferably, the driving device includes fixed block, and the lower surface of fixed block is fixedly connected with the top of drive roll,
The upper surface of the fixed block is fixedly connected by motor with the upper surface of culture chamber interior wall.
Preferably, the regulating device includes 3rd bearing, and third shaft is socketed in 3rd bearing, and third shaft
Outer surface be fixedly connected with the outer surface of driving wheel, the right end of the third shaft is fixedly connected with the left side for turning round block.
Preferably, the quantity of the threaded post is four, and the hand of spiral of two threaded posts in top is on the contrary, and lower section two
The hand of spiral of a threaded post is opposite.
Preferably, the left side of the incubator is fixedly installed with power supply, and the left side of power supply is provided with switch.
Preferably, the input terminal of the switch is electrically connected by conducting wire with the output end of power supply, the output end of the switch
It is electrically connected by conducting wire with the input terminal of motor.
(3) beneficial effect
The utility model has the beneficial effects that:
1, anti-tumor experiment tumor cell culture device, passes through regulating device, driving wheel, driven wheel, belt, cunning
The mutual cooperation of block, threaded post, drive roll and driven voller, culture bottle are placed between drive roll and driven voller, and motor drives
Fixed block slowly rotates, and fixed block drives drive roll to be rotated, so that culture bottle be driven to be rotated, carries out cell adherent
Culture realizes adherent suspension and cultivates two-in-one function, and regulating device drives the second shaft and threaded post rotation, due to threaded post
Position fix, so that thread barrel be made to drive two sliding blocks close to each other or remote under the action of being threaded in threaded post
From, realize the distance between driven voller and drive roll adjusting, rotated suitable for culture bottle of different sizes, improve training
Support the practicability of device.
2, anti-tumor experiment tumor cell culture device, passes through sliding block, sliding slot, driven voller, drive roll and incubator
Mutual cooperation, two thread barrels drive driven vollers to be moved, by setting sliding block and sliding slot, reduce by two sliding blocks
Frictional force between thread barrel and incubator improves the stability in two driven voller moving process.
3, anti-tumor experiment tumor cell culture device, by the way that regulating device is arranged, staff utilizes torsion block band
Dynamic driving wheel rotation, the outer surface due to turning round block are provided with anti-skid chequer, the frictional force for turning round block surface are increased, to be conducive to work
Make personnel the distance between driven voller and drive roll is adjusted.
Detailed description of the invention
Fig. 1 is the schematic diagram of the section structure that the utility model is faced；
Fig. 2 is the structural schematic diagram of the right view of the utility model；
Fig. 3 is the structural schematic diagram amplified at the utility model A；
Fig. 4 is the structural schematic diagram amplified at the utility model B.
In figure: 1 incubator, 2 first rotating shafts, 3 first bearings, 4 drive rolls, 5 sliding slots, 6 second shafts, 7 second bearings, 8
Block, 92 third shafts, 93 3rd bearings, 10 driven wheels, 11 skins are turned round in driving device, 81 motors, 82 fixed blocks, 9 regulating devices, 91
Band, 12 driven vollers, 13 driving wheels, 14 power supplys, 15 switches, 16 threaded posts, 17 sliding blocks, 18 thread barrels.
Specific embodiment
The following will be combined with the drawings in the embodiments of the present invention, carries out the technical scheme in the embodiment of the utility model
Clearly and completely describe, it is clear that the described embodiments are only a part of the embodiments of the utility model, rather than whole
Embodiment.Based on the embodiments of the present invention, those of ordinary skill in the art are without making creative work
Every other embodiment obtained, fall within the protection scope of the utility model.
As shown in Figs 1-4, the utility model provides a kind of technical solution: a kind of anti-tumor experiment is filled with tumor cell culture
It sets, including incubator 1, the lower surface of 1 inner wall of incubator is connected with first bearing 3, and is socketed with first rotating shaft in first bearing 3
2, and the top of first rotating shaft 2 is fixedly connected by drive roll 4 with the lower surface of driving device 8, it is main by the way that drive roll 4 is arranged
The surface of dynamic roller 4 is provided with rubber pad, the frictional force between drive roll 4 and culture bottle is increased, to improve 4 band of drive roll
Stability in dynamic culture bottle rotary course, driving device 8 include fixed block 82, and the lower surface of fixed block 82 and drive roll 4
Top be fixedly connected, by the way that fixed block 82 is arranged, fixed block 82 can be improved connecing between 81 output shaft of motor and drive roll 4
Contacting surface product, to improve the stability connected between drive roll 4 and motor 81, the upper surface of fixed block 82 by motor 81 with
The upper surface of 1 inner wall of incubator is fixedly connected, and the upper surface of driving device 8 is fixedly connected with the upper surface of 1 inner wall of incubator, is led to
Setting driving device 8 is crossed, culture bottle is placed between drive roll 4 and driven voller 12, and motor 81 drives fixed block 82 slowly to revolve
Turn, fixed block 82 drives drive roll 4 to be rotated, so that culture bottle be driven to be rotated, cell is made to carry out adhere-wall culture, realized
Two-in-one function is cultivated in adherent suspension, and the upper and lower surfaces of 1 inner wall of incubator are opened up there are two sliding slot 5, and sliding
Sliding block 17 is slidably connected in slot 5.
The left side of sliding block 17 is connect by thread barrel 18 with the outer surface thread of threaded post 16, and the quantity of threaded post 16 is
Four, and the hand of spiral of two threaded posts 16 in top is on the contrary, by setting threaded post 16, since the position of threaded post 16 is solid
It is fixed, so that thread barrel 18 be made to drive two sliding blocks 17 close to each other or remote under the action of being threaded in threaded post 16
From, the adjusting of the distance between driven voller 12 and drive roll 4 is realized, is rotated suitable for culture bottle of different sizes, and under
Side two threaded posts 16 hand of spiral on the contrary, and the mutually separate one end of threaded post 16 of top two be fixedly connected to second turn
Axis 6 is consolidated using the second shaft 6 between threaded post 16 and driven wheel 10 by the second shaft 6 of setting and second bearing 7
Fixed, the second shaft 6 rotates in second bearing 7, reduces the frictional force between the second shaft 6 and incubator 1, and two second
The mutually separate one end of shaft 6 is socketed with second bearing 7, and two second bearings 7 are connected to the inner wall of sliding slot 5, pass through setting
Sliding slot 5 reduces the frictional force between thread barrel 18 and incubator 1, improves the stabilization in two 12 moving process of driven voller
Property.
The left and right side of drive roll 4 is provided with driven voller 12, and the both ends of two driven vollers 12 respectively with two
One end of one shaft, 2 opposite face is fixedly connected, and by the way that driven voller 12 is arranged, the outer surface of driven voller 12 is provided with anti-skid chequer, is increased
Big frictional force between driven voller 12 and culture bottle, and two first rotating shafts 2 are socketed with first bearing 3, and two first
Bearing 3 is respectively engaged with the opposite face of two sliding blocks 17, and the right end of two the second shafts 6 of right side is fixedly connected to driven wheel
10, and the inner surface of the outer surface of two driven wheels 10 and belt 11 overlaps, by the way that belt 11 is arranged, staff utilizes torsion block
91 drive driving wheel 13 to rotate, and driving wheel 13 drives two driven wheels 10 to rotate together by belt 11, to drive second turn
Axis 6 drives, and two driven wheels 10 are sequentially connected by the outer surface of belt 11 and driving wheel 13, and driving wheel 13 is fixedly connected on
The outer surface of regulating device 9, regulating device 9 include 3rd bearing 93, and by the way that regulating device 9 is arranged, staff utilizes torsion block
91 drive driving wheel 13 to rotate, and the outer surface due to turning round block 91 is provided with anti-skid chequer, increase the frictional force for turning round 91 surface of block, from
And is conducive to staff and the distance between driven voller 12 and drive roll 4 are adjusted, and be socketed in 3rd bearing 93
Three shafts 92, and the outer surface of third shaft 92 is fixedly connected with the outer surface of driving wheel 13, the right end of third shaft 92 and torsion
The left side of block 91 is fixedly connected, and by setting third shaft 92 and 3rd bearing 93, staff drives master by turning round block 91
Driving wheel 13 is rotated, and improves the flexibility in 13 rotary course of driving wheel, and the left side of regulating device 9 is connected to culture
The right side of case 1, the left side of incubator 1 is fixedly installed with power supply 14, and the left side of power supply 14 is provided with switch 15, passes through
Power supply 14 is set, provides electric power for motor 81, convenient for driving culture bottle to be rotated, cell is made to carry out adhere-wall culture, switch 15
Input terminal be electrically connected with the output end of power supply 14 by conducting wire, the output end of switch 15 passes through the input terminal of conducting wire and motor 81
Electrical connection.
The operating procedure of the utility model are as follows:
S1, firstly, culture bottle is placed between drive roll 4 and driven voller 12 by staff, motor 81, which drives, to be fixed
Block 82 slowly rotates, and fixed block 82 drives drive roll 4 to be rotated, so that culture bottle be driven to be rotated, pastes cell
Wall culture realizes adherent suspension and cultivates two-in-one function；
S2, then, staff can drive the second shaft 6 and threaded post 16 to rotate using regulating device 9, due to screw thread
The position of column 16 is fixed, so that thread barrel 18 be made to drive two sliding blocks 17 mutual under the action of being threaded in threaded post 16
It is close or separate, the adjusting of the distance between driven voller 12 and drive roll 4 is realized, is carried out suitable for culture bottle of different sizes
Rotation, improves the practicability of culture apparatus；
S3, finally, staff using turn round block 91 drive driving wheel 13 rotate, due to turn round block 91 outer surface be provided with it is anti-
Sliding line, increases the frictional force for turning round 91 surface of block, and after the cell in culture bottle carries out roller bottle culture, staff will be cultivated
It is taken out on bottle driven voller 12 and drive roll 4.
Above-described specific embodiment, to the purpose of this utility model, technical scheme and beneficial effects carried out into
One step is described in detail, it should be understood that being not used to limit the foregoing is merely specific embodiment of the present utility model
The utility model processed, within the spirit and principle of the utility model, any modification, equivalent substitution, improvement and etc. done,
It should be included within the scope of protection of this utility model.
Claims (6)
1. a kind of anti-tumor experiment tumor cell culture device, including incubator (1), it is characterised in that: the incubator (1)
The lower surface of inner wall is connected with first bearing (3), and is socketed with first rotating shaft (2) in first bearing (3), and first rotating shaft (2)
Top be fixedly connected by drive roll (4) with the lower surface of driving device (8), the upper surface of the driving device (8) and training
The upper surface for supporting case (1) inner wall is fixedly connected, and the upper and lower surfaces of incubator (1) inner wall are opened up there are two sliding slot
(5), sliding block (17) and in sliding slot (5) are slidably connected；
The left side of the sliding block (17) is connect by thread barrel (18) with the outer surface thread of threaded post (16), and top two
The mutually separate one end of threaded post (16) is fixedly connected to the second shaft (6), and the end cap that two the second shafts (6) are mutually separate
It is connected to second bearing (7), and two second bearings (7) are connected to the inner wall of sliding slot (5)；
The left and right side of the drive roll (4) is provided with driven voller (12), and the both ends of two driven vollers (12) respectively with
One end of two first rotating shaft (2) opposite faces is fixedly connected, and two first rotating shafts (2) are socketed with first bearing (3), and two
A first bearing (3) is respectively engaged with the opposite face of two sliding blocks (17), and the right end of two the second shafts of right side (6) is fixed
It is connected with driven wheel (10), and the inner surface of the outer surface of two driven wheels (10) and belt (11) overlaps, and two driven wheels
(10) it is sequentially connected by the outer surface of belt (11) and driving wheel (13), the driving wheel (13) is fixedly connected on regulating device
(9) outer surface, and the left side of regulating device (9) is connected to the right side of incubator (1).
2. anti-tumor experiment according to claim 1 tumor cell culture device, it is characterised in that: the driving device
It (8) include fixed block (82), and the lower surface of fixed block (82) is fixedly connected with the top of drive roll (4), the fixed block
(82) upper surface is fixedly connected by motor (81) with the upper surface of incubator (1) inner wall.
3. anti-tumor experiment according to claim 1 tumor cell culture device, it is characterised in that: the regulating device
It (9) include 3rd bearing (93), and be socketed with third shaft (92) in 3rd bearing (93), and the outer surface of third shaft (92)
It is fixedly connected with the outer surface of driving wheel (13), the fixed company of the right end of the third shaft (92) and the left side for turning round block (91)
It connects.
4. anti-tumor experiment according to claim 1 tumor cell culture device, it is characterised in that: the threaded post
(16) quantity be four, and two threaded posts (16) in top hand of spiral on the contrary, and two threaded posts (16) in lower section spiral shell
Line is contrary.
5. anti-tumor experiment according to claim 1 tumor cell culture device, it is characterised in that: the incubator
(1) left side is fixedly installed with power supply (14), and the left side of power supply (14) is provided with switch (15).
6. anti-tumor experiment according to claim 5 tumor cell culture device, it is characterised in that: the switch (15)
Input terminal be electrically connected with the output end of power supply (14) by conducting wire, the output end for switching (15) passes through conducting wire and motor
(81) input terminal electrical connection.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920190610.0U CN209619367U (en) | 2019-02-12 | 2019-02-12 | Anti-tumor experiment tumor cell culture device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920190610.0U CN209619367U (en) | 2019-02-12 | 2019-02-12 | Anti-tumor experiment tumor cell culture device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN209619367U true CN209619367U (en) | 2019-11-12 |
Family
ID=68453409
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201920190610.0U Expired - Fee Related CN209619367U (en) | 2019-02-12 | 2019-02-12 | Anti-tumor experiment tumor cell culture device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN209619367U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111337493A (en) * | 2020-03-18 | 2020-06-26 | 湖北和诺生物工程股份有限公司 | Tobacco cell suspension culture solution detection device and method |
| CN112522105A (en) * | 2021-01-07 | 2021-03-19 | 华润昂德生物药业有限公司 | Novel CHO cell bottle culture all-in-one machine |
-
2019
- 2019-02-12 CN CN201920190610.0U patent/CN209619367U/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111337493A (en) * | 2020-03-18 | 2020-06-26 | 湖北和诺生物工程股份有限公司 | Tobacco cell suspension culture solution detection device and method |
| CN111337493B (en) * | 2020-03-18 | 2022-12-06 | 湖北和诺生物工程股份有限公司 | Tobacco cell suspension culture solution detection device and method |
| CN112522105A (en) * | 2021-01-07 | 2021-03-19 | 华润昂德生物药业有限公司 | Novel CHO cell bottle culture all-in-one machine |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20191112 Termination date: 20210212 |