CN112522105A - Novel CHO cell bottle culture all-in-one machine - Google Patents
Novel CHO cell bottle culture all-in-one machine Download PDFInfo
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- CN112522105A CN112522105A CN202110019454.3A CN202110019454A CN112522105A CN 112522105 A CN112522105 A CN 112522105A CN 202110019454 A CN202110019454 A CN 202110019454A CN 112522105 A CN112522105 A CN 112522105A
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/02—Form or structure of the vessel
- C12M23/08—Flask, bottle or test tube
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- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
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- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/48—Holding appliances; Racks; Supports
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- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/50—Means for positioning or orientating the apparatus
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M37/00—Means for sterilizing, maintaining sterile conditions or avoiding chemical or biological contamination
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Abstract
The invention discloses a novel CHO cell bottle culture all-in-one machine which comprises a constant temperature incubator main body shell, wherein first universal wheels are arranged at four corners of the lower end of the constant temperature incubator main body shell, a door frame is connected to the left side shaft of the front end of the constant temperature incubator main body shell, a protective glass plate is arranged on the front side of the door frame, an incubator control panel is arranged at the upper left corner of the door frame and arranged on the outer side of the protective glass plate, a supporting plate is fixedly connected to the lower end of the inner side of the constant temperature incubator main body shell, and a containing groove is formed in the lower side of the supporting plate. This novel CHO cell bottle culture all-in-one can be convenient for laborsaving will change the bottle machine and place the inside of incubator or will change the bottle machine and take out from the inside of incubator, reduce staff's intensity of labour, guarantee the steady when changeing the bottle machine and remove, and can be stable fix changeing bottle machine position to be convenient for disinfect the sterilization to incubator inside.
Description
Technical Field
The invention relates to the technical field of cell culture, in particular to a novel CHO cell bottle culture all-in-one machine.
Background
Cell culture refers to a method for simulating in vivo environment in vitro to enable cells to survive, grow, reproduce and maintain main structures and functions, and is also called as cell cloning technology, and a cell culture box is equipment capable of simulating cell survival environment and provides an environment suitable for growth and reproduction for cells.
But current cell culture case is not convenient for place and shift the bottle machine of commentaries on classics, and be not convenient for carry out stable fixed to changeing the bottle machine, and be not convenient for carry out sterilization treatment to the box inside, need use the bottle machine of commentaries on classics to drive the blake bottle during adherence cell culture and rotate, and current incubator is not convenient for place the incubator inside with changeing the bottle machine, intensity of labour is higher during the operation, and change the unable stable fixed in the inside of bottle machine at the incubator, make the incubator if need remove, inside commentaries on classics bottle chance causes the collision to the incubator inner wall, the inside facility of loss incubator.
Disclosure of Invention
The invention aims to provide a novel CHO cell bottle culture all-in-one machine, which aims to solve the problems that the existing cell culture box in the background technology is inconvenient to place and transfer a bottle rotating machine, is inconvenient to stably fix the bottle rotating machine and is inconvenient to sterilize the interior of a box body.
In order to achieve the purpose, the invention provides the following technical scheme: a novel CHO cell bottle culture all-in-one machine comprises a constant temperature incubator main body shell, wherein universal wheels I are arranged at four corners of the lower end of the constant temperature incubator main body shell, a door frame is connected to the left side shaft of the front end of the constant temperature incubator main body shell, a protective glass plate is arranged at the front side of the door frame, an incubator control panel is arranged at the upper left corner of the door frame and is arranged on the outer side of the protective glass plate, a support plate is fixedly connected to the lower end of the inner side of the constant temperature incubator main body shell, a containing groove is arranged on the lower side of the support plate, a movable opening is arranged on the lower side of the front end of the containing groove, a movable plate is connected to the inner side of the containing groove in a sliding mode, reinforcing ribs are arranged on the surface of the lower end of the movable plate, 2 gripping openings are arranged at the front end of the movable, the sliding rods and the inner sides of the movable sliding chutes form a sliding connection structure, the movable sliding chutes are respectively arranged at the left side and the right side of the accommodating groove, the upper side of the supporting plate is provided with a bottle rotating machine base, four corners of the lower end surface of the bottle rotating machine base are respectively provided with a second universal wheel, the lower sides of the second universal wheels are attached to the upper surface of the supporting plate, the front side of the bottle rotating machine base is provided with a bottle rotating machine operating panel, the four corners of the upper end of the bottle rotating machine base are respectively and fixedly connected with supporting columns, the top ends of the supporting columns are respectively and fixedly connected with the four corners of the lower end surface of the top plate, the supporting columns are equidistantly provided with 4 supporting frames, the inner sides of the supporting frames are respectively provided with a supporting rotating shaft, the front end and the rear end of the supporting shaft respectively form a bearing connection structure with the front side and the rear end of the supporting frame, the front side of, and spacing spout sets up respectively in the inside left and right sides of constant temperature incubator main body cover, the upper and lower both ends of support column rear side all laminate mutually with limit stop, and the equal fixed connection of limit stop is on the inside rear side wall of constant temperature incubator main body cover, the upside of roof is provided with square bottle culture platform, and the equal fixed connection of square bottle culture platform is inboard in the upper end of constant temperature incubator main body cover, the left and right sides of the inside rear side wall of constant temperature incubator main body cover all is provided with the mounting groove, and the ultraviolet ray disinfection fluorescent tube is all installed to the inboard of mounting groove.
Preferably, install the relief pressure valve on the constant temperature incubator main part shell, and both ends all are provided with temperature sensor about the inside of constant temperature incubator main part shell to the internally mounted of constant temperature incubator main part shell has CO2 infrared sensor, and the inner wall of constant temperature incubator main part shell is mirror surface stainless steel welded structure moreover.
Preferably, the protective glass plate is a double-layer hollow glass plate, and an LCD (liquid crystal display) and an operation key are arranged on the incubator control panel at the upper left corner of the protective glass plate.
Preferably, the strengthening rib sets up in the lower extreme surface of fly leaf with the even form of equidistance, and both ends downside around the strengthening rib all is provided with the inclined plane.
Preferably, the structure shape of the gripping opening is a kidney-shaped hole, the gripping opening penetrates through the movable plate, an arc-shaped chamfer is arranged on the lower side of the gripping opening, and the position of the gripping opening corresponds to the position of the movable opening.
Preferably, the support rotating shafts are uniformly arranged on each layer of support frame in an equidistant mode, the structural shape of the support frame is a rectangular square frame, and 5 support rotating shafts are arranged on each layer of support frame.
Preferably, the structural shape of the limiting sliding groove is 7-shaped, the upper end of the limiting sliding groove is provided with a circular arc groove, and the circular arc groove in the limiting sliding groove is matched with the structural shape of the movable stop lever.
Preferably, the structure shape of the limit stop is a rectangular cube, and the limit stop is made of a soft material.
Preferably, all square bottle culture platforms are passed to the mounting groove, and square bottle culture platform is provided with 4 in the inboard upper end equidistance of constant temperature incubator main part shell.
Compared with the prior art, the invention has the beneficial effects that: this novel CHO cell bottle culture all-in-one can be convenient for laborsaving will change the bottle machine and place the inside of incubator or will change the bottle machine and take out from the inside of incubator, reduce staff's intensity of labour, guarantee the steady when changeing the bottle machine and remove, and can be stable fix to commentaries on classics bottle machine position to be convenient for disinfect the inside of incubator:
1. the movable plate is pulled through the grabbing opening, the movable plate drives the sliding rods on the left side and the right side to slide on the inner side of the movable sliding chute, when the sliding rods slide to the front end of the movable sliding chute, the sliding rods and the movable plate rotate towards the ground together, the lower side of the front end of the movable plate is in contact with the ground, a gentle slope is formed, the bottle rotating machine is conveniently pushed into the culture space through the gentle slope, the moving stability of the bottle rotating machine is improved, and meanwhile, the labor intensity of workers is reduced;
2. support through limit stop to bottle rotating machine base and support column, then through slip activity pin, make the activity pin slide to the lower extreme along spacing spout, withstand the support column through the activity pin, restrict to the holistic position of bottle rotating machine, improve the stability of bottle rotating machine in the incubator inside, prevent to change the bottle rotating machine and cultivate inside rocking of cultivateing and cause the influence to the cell cultivation
3. Carry out comprehensive disinfection and sterilization to the inside of incubator through ultraviolet ray disinfection fluorescent tube, eliminate outside bacterium and cause the influence to cell culture.
Drawings
FIG. 1 is a schematic perspective view of the present invention;
FIG. 2 is a schematic top view of a movable plate according to the present invention;
FIG. 3 is a schematic perspective view of the present invention with the door frame removed;
FIG. 4 is an enlarged view of point A in FIG. 3 according to the present invention
FIG. 5 is a schematic view of the present invention with the door frame removed;
FIG. 6 is an enlarged view of point B in FIG. 5 according to the present invention
FIG. 7 is a schematic side sectional view of the present invention;
FIG. 8 is an enlarged view of point C of FIG. 7 according to the present invention.
In the figure: 1. a constant temperature incubator main body shell; 2. a first universal wheel; 3. a door frame; 4. a cover glass plate; 5. an incubator control panel; 6. a support plate; 7. a receiving groove; 8. a movable opening; 9. a movable plate; 10. reinforcing ribs; 11. a grip opening; 12. a slide bar; 13. a movable chute; 14. a bottle rotating machine base; 15. an operation panel of the bottle rotating machine; 16. a second universal wheel; 17. a support pillar; 18. a support frame; 19. a support shaft; 20. a top plate; 21. a movable stop lever; 22. a limiting chute; 23. a limit stop block; 24. a square bottle culture platform; 25. mounting grooves; 26. ultraviolet ray disinfection lamp tube.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Referring to fig. 1-8, the present invention provides a technical solution: a novel CHO cell bottle culture all-in-one machine comprises a constant temperature incubator main body shell 1, a first universal wheel 2, a door frame 3, a protective glass plate 4, an incubator control panel 5, a support plate 6, a containing groove 7, a movable opening 8, a movable plate 9, a reinforcing rib 10, a gripping opening 11, a sliding rod 12, a movable sliding groove 13, a spinner base 14, a spinner operation panel 15, a second universal wheel 16, a support column 17, a support frame 18, a support rotating shaft 19, a top plate 20, a movable stop lever 21, a limit sliding groove 22, a limit stop 23, a square bottle culture platform 24, a mounting groove 25 and an ultraviolet disinfection lamp tube 26, wherein the first universal wheel 2 is arranged at four corners of the lower end of the constant temperature incubator main body shell 1, the door frame 3 is connected with a left shaft at the front end of the constant temperature incubator main body shell 1, the protective glass plate 4 is arranged at the front side of the door frame 3, the incubator control panel 5 is arranged at the upper left corner, the incubator control panel 5 is arranged on the outer side of the protective glass plate 4, the lower end of the inner side of the constant temperature incubator main body housing 1 is fixedly connected with a support plate 6, the lower side of the support plate 6 is provided with a containing groove 7, the lower side of the front end of the containing groove 7 is provided with a movable opening 8, the inner side of the containing groove 7 is connected with a movable plate 9 in a sliding manner, the lower end surface of the movable plate 9 is provided with a reinforcing rib 10, the front end of the movable plate 9 is provided with 2 gripping openings 11, the left side and the right side of the rear end of the movable plate 9 are connected with a sliding rod 12 in a uniform manner, the sliding rod 12 and the inner side of a movable sliding groove 13 form a sliding connection structure, the movable sliding grooves 13 are respectively arranged on the left side and the right side of the containing groove 7, the upper side of the support plate 6 is provided with a bottle rotating machine base 14, four corners of the lower end surface of the, the front side of the bottle rotating machine base 14 is provided with a bottle rotating machine operating panel 15, four corners of the upper end of the bottle rotating machine base 14 are fixedly connected with supporting columns 17, the top ends of the supporting columns 17 are respectively fixedly connected with four corners of the lower end surface of a top plate 20, 4 supporting frames 18 are equidistantly arranged on the supporting columns 17, the inner sides of the supporting frames 18 are respectively provided with a supporting rotating shaft 19, the front end and the rear end of the supporting rotating shaft 19 respectively form a bearing connecting structure with the front side and the rear side of the supporting frames 18, the front side of the supporting columns 17 is provided with a movable stop lever 21, the left end and the right end of the movable stop lever 21 respectively form a sliding connecting structure with a limiting sliding chute 22, the limiting chutes 22 are respectively arranged on the left side and the right side inside the constant temperature incubator main body shell 1, the upper end and the lower end of the rear side of the supporting columns 17 are respectively attached to a limiting stop, the upside of roof 20 is provided with square bottle culture platform 24, and the equal fixed connection of square bottle culture platform 24 is inboard in the upper end of incubator main body cover 1, and the left and right sides of the inside back lateral wall of incubator main body cover 1 all is provided with mounting groove 25, and ultraviolet ray disinfection fluorescent tube 26 is all installed to the inboard of mounting groove 25.
Install the relief pressure valve on the constant temperature incubator main body cover 1, and both ends all are provided with temperature sensor about the inside of constant temperature incubator main body cover 1, and the internally mounted of constant temperature incubator main body cover 1 has CO2 infrared sensor, and the inner wall of constant temperature incubator main body cover 1 is mirror surface stainless steel welded structure, can be convenient for ensure the operating stability through the relief pressure valve, be convenient for the temperature condition in the real-time supervision incubator through temperature sensor, and can detect the concentration of carbon dioxide through CO2 infrared sensor, in order to ensure that the inside of incubator reaches cell culture's prerequisite.
The strengthening rib 10 sets up in the lower extreme surface of fly leaf 9 with the even form of equidistance, and both ends downside all is provided with the inclined plane around the strengthening rib 10, can be convenient for improve the overall structure intensity of fly leaf 9 through the strengthening rib 10 of equidistance evenly distributed, and can be convenient for fly leaf 9 slope through the inclined plane at both ends around strengthening rib 10 and place subaerial, form the gentle slope with ground, be convenient for change the bottle machine and remove.
The structure shape of the gripping opening 11 is a kidney-shaped hole, the gripping opening 11 penetrates through the movable plate 9, the lower side of the gripping opening 11 is provided with a circular arc-shaped chamfer, the position of the gripping opening 11 corresponds to the position of the movable opening 8, a hand can be conveniently inserted into the position of the gripping opening 11 through the movable opening 8 for gripping, and then the movable plate 9 is pulled to draw out or store the movable plate 9.
The structural shape of limiting sliding groove 22 is 7-shaped, and the upper end of limiting sliding groove 22 is provided with a circular arc-shaped groove, and the circular arc-shaped groove on limiting sliding groove 22 is matched with the structural shape of movable stop lever 21, so that the bottle rotating machine can be fixed through the matching of limiting sliding groove 22 and movable stop lever 21, the bottle rotating machine is placed to rock in the incubator, and the movable stop lever 21 is convenient to store and place through the groove in the upper end of limiting sliding groove 22.
The structure shape of limit stop 23 is the rectangle cube, and limit stop 23's material is soft material, can be convenient for support and cushion the rear side of commentaries on classics bottle machine through limit stop 23, restricts and protects the commentaries on classics bottle machine.
Mounting groove 25 passes all square bottle culture platforms 24, and square bottle culture platforms 24 are provided with 4 in the inboard upper end equidistance of constant temperature incubator main part shell 1, can be convenient for carry out the disinfection of disinfecting comprehensively to the inside of incubator through mounting groove 25 internally mounted's ultraviolet ray disinfection fluorescent tube 26, prevents that the cell culture in the external bacterium influence blake bottle.
The working principle is as follows: according to fig. 2, 3 and 5, the hand is first inserted inside the activity opening 8 and then inside the grip opening 11;
then the movable plate 9 is pulled, and the movable plate 9 drives the sliding rods 12 at the left side and the right side to slide at the inner side of the movable sliding chute 13;
when the sliding rod 12 slides to the front end of the movable sliding chute 13, the sliding rod 12 rotates at the end of the movable sliding chute 13;
the sliding rod 12 rotates together with the movable plate 9 towards the ground direction, so that the lower side of the front end of the movable plate 9 is in contact with the ground to form a gentle slope;
according to fig. 7, the gentle slope formed by the movable plate 9 facilitates pushing the bottle rotating machine onto the support plate 6, the rear sides of the bottle rotating machine base 14 and the support columns 17 are brought into contact with the limit stoppers 23, and then the movable plate 9 is retracted into the receiving groove 7;
then, the movable stop lever 21 is slid to enable the movable stop lever 21 to slide to the lower end along the limiting sliding groove 22, and the movable stop lever 21 props against the supporting column 17 to limit the position of the whole bottle rotating machine;
starting the bottle rotating machine through the bottle rotating machine operation panel 15, driving the culture bottle to rotate through the supporting rotating shaft 19, and culturing adherent cells;
other stationary culture dishes can be placed on the square bottle culture platform 24, and the inside of the incubator can be sterilized and disinfected completely through the ultraviolet disinfection lamp 26, so that the influence of external bacteria on cell culture is eliminated, and the content which is not described in detail in the specification belongs to the prior art which is well known to a person skilled in the art.
It is to be understood that the terms "central," "longitudinal," "lateral," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," and the like are used in the orientations and positional relationships indicated in the drawings for the purpose of convenience and simplicity of description, and do not indicate or imply that the referenced devices or components must be in a particular orientation, constructed and operated in a particular orientation, and are not to be considered limiting of the scope of the present invention.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (9)
1. The utility model provides a novel CHO cell bottle culture all-in-one, includes constant temperature incubator main part shell (1), its characterized in that: the lower end four corners of the constant temperature incubator main body shell (1) are respectively provided with a first universal wheel (2), the front end left side shaft of the constant temperature incubator main body shell (1) is connected with a door frame (3), a protective glass plate (4) is arranged on the front side of the door frame (3), an incubator control panel (5) is arranged on the upper left corner of the door frame (3), the incubator control panel (5) is arranged on the outer side of the protective glass plate (4), the inner side lower end of the constant temperature incubator main body shell (1) is fixedly connected with a support plate (6), the lower side of the support plate (6) is provided with a holding groove (7), the front end lower side of the holding groove (7) is provided with a movable opening (8), the inner side of the holding groove (7) is connected with a movable plate (9) in a sliding manner, the lower end surface of the movable plate (9) is provided with a reinforcing rib (10), and the front end of the movable plate (9) is, the left side and the right side of the rear end of the movable plate (9) are connected with sliding rods (12) in an integrated mode, the sliding rods (12) and the inner sides of the movable sliding chutes (13) form a sliding connection structure, the movable sliding chutes (13) are arranged on the left side and the right side of the accommodating groove (7) respectively, a bottle rotating machine base (14) is arranged on the upper side of the supporting plate (6), two universal wheels (16) are mounted at four corners of the lower end surface of the bottle rotating machine base (14), the lower sides of the two universal wheels (16) are attached to the upper surface of the supporting plate (6), a bottle rotating machine operating panel (15) is arranged on the front side of the bottle rotating machine base (14), supporting columns (17) are fixedly connected to four corners of the upper end of the bottle rotating machine base (14), the top ends of the supporting columns (17) are fixedly connected to four corners of the lower end surface of the top plate (20) respectively, and 4 supporting frames (18), and the inner side of the supporting frame (18) is provided with a supporting rotating shaft (19), the front end and the rear end of the supporting rotating shaft (19) respectively form a bearing connecting structure with the front side and the rear side of the supporting frame (18), the front side of the supporting column (17) is provided with a movable stop lever (21), the left end and the right end of the movable stop lever (21) respectively form a sliding connecting structure with a limit sliding chute (22), the limit sliding chutes (22) are respectively arranged at the left side and the right side inside the constant temperature incubator main body shell (1), the upper end and the lower end of the rear side of the supporting column (17) are respectively attached to a limit stop (23), the limit stop (23) is respectively and fixedly connected to the rear side wall inside the constant temperature incubator main body shell (1), the upper side of the top plate (20) is provided with a square bottle culture platform (24), and the square bottle culture platform (24) is respectively and fixedly connected to the inner side of the, the left and right sides of the inside back lateral wall of constant temperature incubator main part shell (1) all is provided with mounting groove (25), and ultraviolet ray disinfection fluorescent tube (26) are all installed to the inboard of mounting groove (25).
2. The integrated CHO cell bottle culture machine according to claim 1, wherein: install the relief pressure valve on constant temperature incubator main part shell (1), and both ends all are provided with temperature sensor about the inside of constant temperature incubator main part shell (1) to the internally mounted of constant temperature incubator main part shell (1) has CO2 infrared sensor, and the inner wall of constant temperature incubator main part shell (1) is mirror surface stainless steel welded structure moreover.
3. The integrated CHO cell bottle culture machine according to claim 1, wherein: the protective glass plate (4) is a double-layer hollow glass plate, and an LCD (liquid crystal display) and an operation key are arranged on the incubator control panel (5) at the upper left corner of the protective glass plate (4).
4. The integrated CHO cell bottle culture machine according to claim 1, wherein: the reinforcing ribs (10) are arranged on the lower end surface of the movable plate (9) in an equidistant and uniform mode, and inclined planes are arranged on the lower sides of the front end and the rear end of each reinforcing rib (10).
5. The integrated CHO cell bottle culture machine according to claim 1, wherein: the structure shape of the gripping opening (11) is a kidney-shaped hole, the gripping opening (11) penetrates through the movable plate (9), an arc-shaped chamfer is arranged on the lower side of the gripping opening (11), and the position of the gripping opening (11) corresponds to the position of the movable opening (8).
6. The integrated CHO cell bottle culture machine according to claim 1, wherein: the supporting rotating shafts (19) are uniformly arranged on each layer of supporting frame (18) in an equidistant mode, the structural shape of the supporting frame (18) is a rectangular square frame, and 5 supporting rotating shafts (19) are arranged on each layer of supporting frame (18).
7. The integrated CHO cell bottle culture machine according to claim 1, wherein: the structural shape of the limiting sliding groove (22) is 7-shaped, the upper end of the limiting sliding groove (22) is provided with a circular arc groove, and the circular arc groove in the limiting sliding groove (22) is matched with the structural shape of the movable stop lever (21).
8. The integrated CHO cell bottle culture machine according to claim 1, wherein: the structure shape of the limit stop (23) is a rectangular cube, and the limit stop (23) is made of soft materials.
9. The integrated CHO cell bottle culture machine according to claim 1, wherein: all square bottle culture platforms (24) are passed in mounting groove (25), and square bottle culture platform (24) are provided with 4 at the inboard upper end equidistance of constant temperature incubator main part shell (1).
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| CN202110019454.3A CN112522105B (en) | 2021-01-07 | 2021-01-07 | CHO cell bottle culture all-in-one machine |
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| US20100304472A1 (en) * | 2007-11-30 | 2010-12-02 | Corestem Co., Ltd. | Cell Culture Apparatus and Mass Automatic Cell Culture Device Having It |
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| JP2016129493A (en) * | 2015-01-13 | 2016-07-21 | 株式会社北川鉄工所 | Clinostat |
| CN207210448U (en) * | 2017-08-04 | 2018-04-10 | 云南生物制药有限公司 | A kind of red blood-cell cultivation rotating-bottle machine |
| CN108707550A (en) * | 2018-06-20 | 2018-10-26 | 郑州源冉生物技术有限公司 | A kind of biotechnology cell culture apparatus |
| CN209619367U (en) * | 2019-02-12 | 2019-11-12 | 蔡宏剑 | Anti-tumor experiment tumor cell culture device |
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