CN209602529U - A kind of fermentor being used to prepare the poly- peptide sugar of sweet dew - Google Patents

A kind of fermentor being used to prepare the poly- peptide sugar of sweet dew Download PDF

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Publication number
CN209602529U
CN209602529U CN201920913794.9U CN201920913794U CN209602529U CN 209602529 U CN209602529 U CN 209602529U CN 201920913794 U CN201920913794 U CN 201920913794U CN 209602529 U CN209602529 U CN 209602529U
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fixedly connected
chamber
tank body
poly
sealing cover
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刘波
魏安那
邓光友
白飞
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LIER PHARMACEUTICAL CO Ltd CHENGDU CITY
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LIER PHARMACEUTICAL CO Ltd CHENGDU CITY
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Abstract

The utility model discloses a kind of fermentors for being used to prepare the poly- peptide sugar of sweet dew, belong to the poly- peptide sugar preparation field of sweet dew, a kind of fermentor being used to prepare the poly- peptide sugar of sweet dew, including tank body, tank body is fixedly connected with demarcation plate inside lower end, the upper and lower side of tank body is separated into fermentation chamber and filter chamber by demarcation plate, sealing cover is threaded on the top inner wall of fermentation chamber, the bottom end of sealing cover is equipped with rabbling mechanism, the top of sealing cover is fixedly installed with the motor driven to rabbling mechanism, tank body offers annular cooling chamber corresponding with fermentation chamber position and ring-shaped heating cavity close to the inside of upper end, annular cooling chamber is located at the inside of ring-shaped heating cavity, the heating at any time of the fermentor may be implemented, cooling effect, convenient for suitably being adjusted to the intracorporal fermentation temperature of tank, fermentation liquid after fermenting simultaneously is by vibrating up and down the thick of movement Filter frame, thin filter frame improve filter effect, effectively improve the DNA purity of fermentation material.

Description

A kind of fermentor being used to prepare the poly- peptide sugar of sweet dew
Technical field
The utility model relates to the poly- peptide sugar preparation fields of sweet dew, are used to prepare the poly- peptide of sweet dew more specifically to one kind The fermentor of sugar.
Background technique
Mannatide, also referred to as α-mannatide or polyactin are a kind of glycosylation peptides macromolecular substances, at present It is clinically used mainly as immunopotentiator, for immunologic hypofunction, the adjuvant treatment of tumour.
It will use fermentor in the poly- peptide sugar preparation process of sweet dew and fermentation process, and the control of temperature carried out to its raw material It is an important step of fermentation, temperature controlled quality directly influences the efficiency of fermentation and the quality of fermentation, existing It is difficult to carry out the cooling that heated up to fermentor inside well in technology;Fermentation liquid needs after fermenting simultaneously are filtered place Reason, fermentation generally requires to carry out by two process equipments with filtering in the prior art, and operation is relatively complicated, and effectively improves Filter effect plays an important role to purification.
For this purpose, it is proposed that a kind of fermentor for being used to prepare the poly- peptide sugar of sweet dew solves one in the presence of the prior art A little problems.
Utility model content
1. technical problems to be solved
Aiming at the problems existing in the prior art, the purpose of this utility model is to provide one kind to be used to prepare the poly- peptide of sweet dew The fermentor of sugar, may be implemented heating at any time, the cooling effect of the fermentor, appropriate convenient for carrying out to the intracorporal fermentation temperature of tank It adjusts, while the fermentation liquid after fermentation improves filter effect, effectively by vibrating up and down the coarse filtration frame moved, thin filter frame Improve the DNA purity of fermentation material.
2. technical solution
To solve the above problems, the utility model adopts the following technical scheme.
A kind of fermentor being used to prepare the poly- peptide sugar of sweet dew, including tank body, the tank body are fixedly connected inside lower end There is a demarcation plate, the upper and lower side of tank body is separated into fermentation chamber and filter chamber by the demarcation plate, on the top inner wall of the fermentation chamber It is threaded with sealing cover, the bottom end of the sealing cover is equipped with rabbling mechanism, and the top of the sealing cover is fixedly installed with pair The motor that rabbling mechanism is driven, the tank body offer annular cooling corresponding with fermentation chamber position close to the inside of upper end Chamber and ring-shaped heating cavity, the annular cooling chamber are located at the inside of ring-shaped heating cavity, the upper and lower side connection of the ring-shaped heating cavity There is snorkel, the upper and lower side of the annular cooling chamber is connected with water service pipe, and the upper and lower of the filter chamber is slidably fitted with respectively Coarse filtration frame and thin filter frame, the bottom both ends of the demarcation plate are fixedly connected to electric pushrod, two electric pushrods Telescopic end be respectively fixedly connected between the upper end of coarse filtration frame, the coarse filtration frame and thin filter frame by guiding device into Row connection, may be implemented heating at any time, the cooling effect of the fermentor, convenient for suitably being adjusted to the intracorporal fermentation temperature of tank Section, while the fermentation liquid after fermentation improves filter effect, effectively mentions by vibrating up and down the coarse filtration frame moved, thin filter frame The DNA purity of high fermentation material.
Further, the rabbling mechanism includes the agitating shaft being rotatably connected in the middle part of sealing cover lower end, the agitating shaft Two sides be fixedly connected sequentially have multiple stirring sheets from top to bottom, and the side wall of stirring sheet offers multiple broken holes, stirring sheet Agitating shaft rotation is driven, certain crushing effect is realized during stirring, the drive shaft of the motor runs through sealing cover simultaneously It is fixedly connected with agitating shaft upper end.
Further, it is fixedly connected to link block on the two sides side wall of the sealing cover, screw thread connects on the link block It is connected to inserted link, the top of the tank body offers the slot to match with inserted link, and inserted link passes through the upper end of elastic string and tank body Side wall is fixedly connected, and further improves the stability that sealing cover is located at tank body top.
Further, the insole portion of the fermentation chamber and filter chamber does not offer top discharge mouth and lower discharge port, and on It is separately installed with valve and lower valve at discharge port and lower discharge port, realizes the discharging of fermentation liquid and filtered fluid.
Further, the guiding device includes the guide rod being fixedly connected on the side wall of partition bottom side, described The lower end of guide rod sequentially passes through coarse filtration frame, thin filter frame and is fixedly connected with fixed plate, and the fixed plate is fixedly connected on On the inner wall of filter chamber, the upper and lower side of the thin filter frame is equipped with compressed spring, and two compressed springs are respectively sleeved at and lead It on bar, realizes that coarse filtration frame and thin filter frame carry out certain vibration processing in the vertical direction, effectively improves filtering effect Fruit.
Further, the guide rod, which is located on the side wall below coarse filtration frame, is socketed with limited post, the limited post Bottom end and the top for being located above compressed spring offset, and the setting of limited post advantageously allows between coarse filtration frame and thin filter frame There are certain intervals, are conducive to the successively filtering of fermentation liquid.
3. beneficial effect
Compared with the prior art, utility model has the advantages that
(1) heating at any time of the fermentor, cooling effect may be implemented in this programme, convenient for the intracorporal fermentation temperature of tank into Row is appropriate to be adjusted, while the fermentation liquid after fermentation passes through the coarse filtration frame for vibrating up and down movement, thin filter frame, is improved to filter and be imitated Fruit effectively improves the DNA purity of fermentation material.
(2) rabbling mechanism includes the agitating shaft being rotatably connected in the middle part of sealing cover lower end, and the two sides of agitating shaft are from top to bottom Being fixedly connected sequentially has multiple stirring sheets, and the side wall of stirring sheet offers multiple broken holes, and stirring sheet drives agitating shaft rotation, Certain crushing effect is realized during stirring.
(3) it is fixedly connected to link block on the two sides side wall of sealing cover, is threaded on link block and passes through elastic string The inserted link being fixedly connected with the upper end side wall of tank body, the top of tank body offer the slot to match with inserted link, further increase Sealing cover is located at the stability on tank body top.
(4) guiding device includes the compressed spring that guide rod, fixed plate and thin filter frame upper and lower position are arranged, and is realized thick Filter frame and thin filter frame carry out certain vibration processing in the vertical direction, effectively improve filter effect.
(5) guide rod, which is located on the side wall below coarse filtration frame, is socketed with limited post, the bottom end of limited post and is located above The top of compressed spring offsets, and the setting of limited post advantageously allows between existing centainly between coarse filtration frame and thin filter frame Every being conducive to the successively filtering of fermentation liquid.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of the utility model;
Fig. 2 is the tank body of the utility model and the top view of ring-shaped heating cavity, annular cooling chamber junction;
Fig. 3 is the structural schematic diagram of the coarse filtration frame of the utility model, thin filter frame and guiding device junction;
Fig. 4 is the structural schematic diagram in the embodiments of the present invention 2.
Figure label explanation:
1 tank body, 2 demarcation plates, 3 fermentation chambers, 4 filter chambers, 5 sealing covers, 6 motors, 7 agitating shafts, 8 stirring sheets, 9 annular-heatings Chamber, 10 annular cooling chambers, 11 snorkels, 12 water service pipes, valve, 14 lower valves, 15 coarse filtration frames, 16 thin filter frames, 17 on 13 Electric pushrod, 18 guide rods, 19 limited posts, 20 fixed plates, 21 compressed springs, 22 cross bars, 23 vibrating springs, 24 clump weights, 25 Electric expansion cylinder, 26 vertical bars.
Specific embodiment
The following is a combination of the drawings in the embodiments of the present utility model;The technical scheme in the embodiment of the utility model is carried out Clearly and completely describe;Obviously;The described embodiments are only a part of the embodiments of the utility model;Rather than whole Embodiment, based on the embodiments of the present invention;Those of ordinary skill in the art are without making creative work Every other embodiment obtained;It fall within the protection scope of the utility model.
In the description of the present invention, it should be noted that term " on ", "lower", "inner", "outside", " top/bottom end " etc. The orientation or positional relationship of instruction is to be based on the orientation or positional relationship shown in the drawings, and is merely for convenience of description the utility model It is described with simplifying, rather than the device or element of indication or suggestion meaning must have a particular orientation, with specific orientation structure It makes and operates, therefore should not be understood as limiting the present invention.In addition, term " first ", " second " are only used for description mesh , it is not understood to indicate or imply relative importance.
In the description of the present invention, it should be noted that unless otherwise clearly defined and limited, term " is pacified Dress ", " being provided with ", " be arranged/connect ", " connection " etc., shall be understood in a broad sense, such as " connection ", may be a fixed connection, can also be with It is to be detachably connected, or be integrally connected;It can be mechanical connection, be also possible to be electrically connected;It can be directly connected, it can also be with Indirectly connected through an intermediary, it can be the connection inside two elements.For the ordinary skill in the art, may be used The concrete meaning of above-mentioned term in the present invention is understood with concrete condition.
Embodiment 1:
Referring to Fig. 1, a kind of fermentor for being used to prepare the poly- peptide sugar of sweet dew, including tank body 1, tank body 1 is inside lower end It is fixedly connected with demarcation plate 2, the upper and lower side of tank body 1 is separated into fermentation chamber 3 and filter chamber 4, fermentation chamber 3 and filtering by demarcation plate 2 The insole portion of chamber 4 does not offer top discharge mouth and lower discharge port, and is separately installed with upper valve at top discharge mouth and lower discharge port Door 13 and lower valve 14 realize the discharging of fermentation liquid and filtered fluid, are threaded with sealing cover on the top inner wall of fermentation chamber 3 5, link block is fixedly connected on the two sides side wall of sealing cover 5, inserted link is threaded on link block, the top of tank body 1 is opened Equipped with the slot to match with inserted link, and inserted link is fixedly connected by elastic string with the upper end side wall of tank body 1, is further improved Sealing cover 5 is located at the stability on 1 top of tank body.
The bottom end of sealing cover 5 is equipped with rabbling mechanism, and the top of sealing cover 5, which is fixedly installed with, drives rabbling mechanism Motor 6, rabbling mechanism includes the agitating shaft 7 being rotatably connected in the middle part of 5 lower end of sealing cover, and the two sides of agitating shaft 7 are from top to bottom Being fixedly connected sequentially has multiple stirring sheets 8, and the side wall of stirring sheet 8 offers multiple broken holes, and stirring sheet 8 is to 7 turns of agitating shaft It is dynamic, certain crushing effect is realized during stirring, the drive shaft of motor 6 is through sealing cover 5 and solid with 7 upper end of agitating shaft Fixed connection.
Tank body 1 offers annular cooling chamber 10 corresponding with 3 position of fermentation chamber close to the inside of upper end referring to FIG. 1-2, With ring-shaped heating cavity 9, annular cooling chamber 10 is located at the inside of ring-shaped heating cavity 9, and the upper and lower side of ring-shaped heating cavity 9 is connected with ventilation Pipe 11, the upper and lower side of annular cooling chamber 10 are connected with water service pipe 12, and annular cooling chamber 10 and ring-shaped heating cavity 9 are to be provided with tank Ring structure inside body 1 has certain annular space, respectively facilitates the filling of liquid and gas, and setting up and down is logical It is provided with solenoid valve on the side wall of water pipe 12 and snorkel 11, and extends outwardly through tank body 1 outside the two.
Fig. 1 and Fig. 3 are please referred to, the upper and lower of filter chamber 4 is slidably fitted with coarse filtration frame 15 and thin filter frame 16 respectively, point The bottom both ends of partition 2 are fixedly connected to electric pushrod 17, and those skilled in the art may be selected suitable electric pushrod 17 and carry out Installation, such as model are as follows: hb-dj806, the telescopic end of two electric pushrods 17 are respectively fixedly connected in the upper of coarse filtration frame 15 End is attached between coarse filtration frame 15 and thin filter frame 16 by guiding device, and coarse filtration frame 15 and thin filter frame 16 are sliding It is dynamic to be socketed on guiding device, and realized by the drive of electric pushrod 17 and moved in vertical direction fan, reach up-down vibration Effect.
Specifically, guiding device includes the guide rod 18 being fixedly connected on 2 bottom end side side wall of demarcation plate, guide rod 18 Lower end sequentially pass through coarse filtration frame 15, thin filter frame 16 and be fixedly connected with fixed plate 20, fixed plate 20 was fixedly connected on On the inner wall of filter chamber 4, the upper and lower side of thin filter frame 16 is equipped with compressed spring 21, and two compressed springs 21 are respectively sleeved at and lead To on bar 18, realizes that coarse filtration frame 15 and thin filter frame 16 carry out certain vibration processing in the vertical direction, effectively improve Filter effect, guide rod 18, which is located on the side wall of 15 lower section of coarse filtration frame, is socketed with limited post 19, the bottom end and position of limited post 19 It offsets in the top of top compressed spring 21, the setting of limited post 19 advantageously allows between coarse filtration frame 15 and thin filter frame 16 There are certain intervals, are conducive to the successively filtering of fermentation liquid.
In peptide sugar fermenting raw materials poly- using present apparatus progress sweet dew, the poly- peptide glycogen material of sweet dew is poured into the hair in tank body 1 In ferment chamber 3, spiral lock closely covers 5, after fixing sealing cover 5, by the inserted links of 1 top two sides of tank body to sealing cover 5 into Row repositions, and avoids motor 6 from impacting when driving rabbling mechanism movement to the stability of sealing cover 5, motor 6 drives stirring Mechanism is rotated, to raw material be sufficiently stirred, while the mounting temperature sensor in fermentation chamber 3, in figure not It marks, those skilled in the art may be selected suitable temperature sensor and install, temperature sensor and extraneous computer end network Connection monitors the temperature in fermentation chamber 3 in real time, so as to according to broth temperature needs, by control upper end snorkel 11 Solenoid valve, solenoid valve opens and is passed through air hot steam into ring-shaped heating cavity 9, and snorkel 11 is connected with external heat source, leads to It crosses interlayer and heating effect is realized to the raw material in fermentation chamber 3, improve fermentation efficiency, when should need cooling down together, in opening The solenoid valve on water service pipe 12 to be held, coolant liquid is injected into annular cooling chamber 10, water service pipe 12 is connected with extraneous cooling water source, To reach cooling effect, annular cooling chamber 10 is located at the inside of ring-shaped heating cavity 9, can effectively improve cooling efficiency, in order to have Temperature in effect control fermentation chamber 3;
After fermentation, valve 13 in starting, fermentation liquid import filter chamber 4 in, by coarse filtration frame 15 setting up and down, Thin filter frame 16 is filtered processing to fermentation liquid, in the process, can start the electric pushrod 17 of 2 lower end two sides of demarcation plate, The oscilaltion back and forth of electric pushrod 17, electric pushrod 17 drive coarse filtration frame 15 to be vibrated up and down in the vertical direction, thick mistake Filter frame 15 passes downwardly through limited post 19 along guide rod 18 and carries out extrusion and vibration to thin filter frame 16, and thin filter frame 16 is in compressed spring The vibration that can carry out certain distance under the action of 21 along the vertical direction, effectively makes fermentation liquid be not easy to be deposited on filter frame, mentions High filtration effect.
Embodiment 2:
Referring to Fig. 4, the present embodiment difference from example 1 is that: by the matching in conjunction with rabbling mechanism of motor 25 The fit structure that structure is substituted for electric expansion cylinder 25 Yu vibrating mechanism structure is closed, electric expansion cylinder 25 is fixedly mounted on sealing cover 5 upper ends, the telescopic end of electric expansion cylinder 25 is through sealing cover 5 and has been fixedly connected with vertical bar 26, the two sides side wall of vertical bar 26 from Top to bottm, which is fixedly connected sequentially, multiple cross bars 22, and the lower end of cross bar 22 is fixedly connected with multiple vibrating springs 23, vibrating spring 23 lower end is fixedly connected with clump weight 24, and after starting electric expansion cylinder 25, vertical bar 26 drives multiple cross bars in the vertical direction 22 move up and down, to drive the up-down vibration of vibrating spring 23, the up-down vibration of cross bar 22 and vibrating spring 23 is moved Swing crushing is also acted as while playing the role of stirring action to fermentation liquid, further increases the degree of being stirred.
The implementation method of the present embodiment and the implementation method of embodiment 1 the difference is that: by motor 25 and rabbling mechanism In conjunction with matching mechanism be substituted for the matching mechanism of electric expansion cylinder 25 Yu vibrating mechanism structure, other the step of it is identical.
It is described above;The only preferable specific embodiment of the utility model;But the protection scope of the utility model is not It is confined to this;Anyone skilled in the art is within the technical scope disclosed by the utility model;It is practical according to this Novel technical solution and its improvement design is subject to equivalent substitution or change;It should all cover in the protection scope of the utility model It is interior.

Claims (6)

1. a kind of fermentor for being used to prepare the poly- peptide sugar of sweet dew, including tank body (1), it is characterised in that: the tank body (1) is under End is internal to be fixedly connected with demarcation plate (2), and the upper and lower side of tank body (1) is separated into fermentation chamber (3) and filtering by the demarcation plate (2) Chamber (4) is threaded with sealing cover (5) on the top inner wall of the fermentation chamber (3), and the bottom end of the sealing cover (5) is equipped with Rabbling mechanism, the top of the sealing cover (5) are fixedly installed with the motor (6) driven to rabbling mechanism, the tank body (1) Annular cooling chamber (10) corresponding with fermentation chamber (3) position and ring-shaped heating cavity (9), the ring are offered close to the inside of upper end Shape cooling chamber (10) is located at the inside of ring-shaped heating cavity (9), and the upper and lower side of the ring-shaped heating cavity (9) is connected with snorkel (11), the upper and lower side of the annular cooling chamber (10) is connected with water service pipe (12), and the upper and lower of the filter chamber (4) slides respectively Coarse filtration frame (15) and thin filter frame (16) are installed, the bottom both ends of the demarcation plate (2) are fixedly connected to electric pushrod (17), the telescopic end of two electric pushrods (17) is respectively fixedly connected in the upper end of coarse filtration frame (15), the coarse filtration It is attached between frame (15) and thin filter frame (16) by guiding device.
2. a kind of fermentor for being used to prepare the poly- peptide sugar of sweet dew according to claim 1, it is characterised in that: the blender Structure includes being rotatably connected on agitating shaft (7) in the middle part of sealing cover (5) lower end, and the two sides of the agitating shaft (7) are from top to bottom successively It is fixedly connected with multiple stirring sheets (8), and the side wall of stirring sheet (8) offers multiple broken holes, the drive shaft of the motor (6) It is fixedly connected through sealing cover (5) and with agitating shaft (7) upper end.
3. a kind of fermentor for being used to prepare the poly- peptide sugar of sweet dew according to claim 1, it is characterised in that: the sealing cover (5) it is fixedly connected to link block on two sides side wall, inserted link, the top of the tank body (1) are threaded on the link block End offers the slot to match with inserted link, and inserted link is fixedly connected by elastic string with the upper end side wall of tank body (1).
4. a kind of fermentor for being used to prepare the poly- peptide sugar of sweet dew according to claim 1, it is characterised in that: the fermentation chamber (3) and the insole portion of filter chamber (4) does not offer top discharge mouth and lower discharge port, and distinguishes at top discharge mouth and lower discharge port Valve (13) and lower valve (14) are installed.
5. a kind of fermentor for being used to prepare the poly- peptide sugar of sweet dew according to claim 1, it is characterised in that: the guiding dress The guide rod (18) including being fixedly connected on the side wall of demarcation plate (2) bottom end side is set, the lower end of the guide rod (18) is successively It through coarse filtration frame (15), thin filter frame (16) and is fixedly connected with fixed plate (20), the fixed plate (20) is fixedly connected on On the inner wall of filter chamber (4), the upper and lower side of the thin filter frame (16) is equipped with compressed spring (21), and two compressed springs (21) it is respectively sleeved on guide rod (18).
6. a kind of fermentor for being used to prepare the poly- peptide sugar of sweet dew according to claim 5, it is characterised in that: the guide rod (18) be located at coarse filtration frame (15) below side wall on be socketed with limited post (19), the bottom end of the limited post (19) and be located at it is upper The top of square compressed spring (21) offsets.
CN201920913794.9U 2019-06-18 2019-06-18 A kind of fermentor being used to prepare the poly- peptide sugar of sweet dew Active CN209602529U (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112322446A (en) * 2020-11-05 2021-02-05 威海海洋职业学院 Add oyster polysaccharide's fig vinegar laboratory fermenting installation
CN112391250A (en) * 2020-12-12 2021-02-23 安徽管仲酒业有限公司 Fermentation cylinder is used to white spirit making with temperature regulation and control function
CN113403194A (en) * 2021-07-22 2021-09-17 漳州添丰生物科技有限公司 Stirring mechanism in microbial fermentation tank
CN114478094A (en) * 2022-01-25 2022-05-13 安徽科技学院 Farmyard manure fermentation system and method
CN116286291A (en) * 2022-12-01 2023-06-23 江苏春江生物科技有限公司 Liver-protecting preparation prepared from fermented Chinese herbal medicines and preparation device

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112322446A (en) * 2020-11-05 2021-02-05 威海海洋职业学院 Add oyster polysaccharide's fig vinegar laboratory fermenting installation
CN112391250A (en) * 2020-12-12 2021-02-23 安徽管仲酒业有限公司 Fermentation cylinder is used to white spirit making with temperature regulation and control function
CN113403194A (en) * 2021-07-22 2021-09-17 漳州添丰生物科技有限公司 Stirring mechanism in microbial fermentation tank
CN114478094A (en) * 2022-01-25 2022-05-13 安徽科技学院 Farmyard manure fermentation system and method
CN116286291A (en) * 2022-12-01 2023-06-23 江苏春江生物科技有限公司 Liver-protecting preparation prepared from fermented Chinese herbal medicines and preparation device

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