CN209563069U - A kind of radiator for PCR detector temperature control system - Google Patents
A kind of radiator for PCR detector temperature control system Download PDFInfo
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- CN209563069U CN209563069U CN201821695051.0U CN201821695051U CN209563069U CN 209563069 U CN209563069 U CN 209563069U CN 201821695051 U CN201821695051 U CN 201821695051U CN 209563069 U CN209563069 U CN 209563069U
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Abstract
The utility model relates to a kind of radiators for PCR detector temperature control system, comprising: temperature control system, heat-conducting mechanism and cooling cabinet;Temperature control system, the system and structure of required temperature control when referring to the operation of PCR detector;Heat-conducting mechanism includes heat-conducting metal layer, heat conducting pipe and heat-conducting liquid;Heat-conducting metal layer is close together by heat-conducting medium with heating and refrigerating device in the temperature control system to radiate is needed;Heat-conducting metal layer includes the cavity equipped with heat-conducting liquid, cavity portion is connected with heat conducting pipe, heat-conducting metal layer inner cavity is communicated with thermally conductive lumen, and the heat of heating and refrigerating device is gone in the intracavitary heat-conducting liquid of heat-conducting metal layer by heat-conducting metal layer in the temperature control system for needing to radiate.The utility model is especially suitable for making radiator portion account for instrument space and being substantially reduced in miniaturization, portable PC R detector, and radiating efficiency can improve while can reduce cost.
Description
Technical field
The utility model belongs to radiator structure field, more particularly to save space, it is energy-efficient, be simple to manufacture, be at low cost
The honest and clean radiator for temperature control system in PCR detector, quickly detects especially suitable for miniaturization, portable PCR, analyzes
In device.
Background technique
Since 1986 by the utility models round pcr such as Mullis, the exploitation of related round pcr and improved work 20
In the past few years never be interrupted, the utility model of various round pcrs constantly give worker one that is engaged in biological study it is another
A is pleasantly surprised.Round pcr has become a basic fundamental of Molecular Biology Lab at present.With life science and doctor
The continuous development of detection is learned, people increasingly wish while guaranteeing PCR atopic, sensitivity, fidelity, Neng Goujin
Amount shortens the time of reaction, i.e. realization fast PCR (Rapid PCR or Fast PCR).Fast PCR technology can not only make sample
It can be expanded as early as possible within the limited time, and detectable sample size can be dramatically increased, it is clear that in high-volume
Pattern detection and infectious disease quick diagnosis etc. will have important application prospect.For example, fast PCR can in clinical detection
Greatly speed up the diagnosis efficiency of disease;Depositing for harmful organism in Rapid identification suspicious item can be effectively helped in biological terrorist
Whether.
Fast PCR technical principle is still established on the basis of Standard PCR principle.Conventional PCR reaction process is usually three
The circulation in big stage, i.e. denaturation stage, annealing stage and extension stage, (in some cases, annealing stage and extension stage could
To merge), the reaction time is the time of the total time plus temperature change between each stage in three above stage.It realizes quickly
PCR, root problem seek to shorten the duration or the time of temperature change in this three big stage, and temperature control system heat dissipation
One of an important factor for speed, efficiency are the decision temperature change time.
Simultaneously with the development of biotechnology, PCR detection, analysis instrument are to miniaturization, integrated, automation, high-throughput
Fast quantitative analysis direction is developed, and provides a kind of possible strategy for the real-time detection of biochemical environmental sample, field assay,
It is had a vast market foreground in terms of medical diagnosis, judicial expertise, food inspection and agricultural breeding system epidemic monitoring.Such as
The miniaturization scene pathogen detection system for the features such as design operation is simple, at low cost, portable and easy to automate is realized
In quick detection of the epidemic outburst scene to infectious disease pathogens.
The core of this type analyzer first is that temperature control system, can be required for different reactions to realize that reactant exists
The temperature of the different phases such as denaturation, renaturation, extension controls.And temperature control system wants control accurately, response quickly, radiator structure
It plays a crucial role.Miniaturization, portable PC R device for fast detecting because its is small in size and convenience feature decide it is scattered
Heat space has very strong limitation, and existing instrument is that the materials such as aluminium or copper radiator and radiator fan radiate,
And the size of radiator and radiator fan directly affects radiating efficiency, therefore under the conditions of meeting instrument performance, cooling fin and dissipate
Hot-air fan accounts for the significant percentage of space of instrument, does not utilize instrument miniaturization, portability.Therefore one kind is designed neither to account for
Space, but heat dissipating method and structure that can be quick, efficient, inexpensive be particularly important.
Utility model content
The technical solution of the utility model: it overcomes the deficiencies of the prior art and provide a kind of for all kinds of PCR detectors
The radiator of temperature control system, especially miniaturization, portable PC R detector, make radiator portion account for instrument space and are substantially reduced,
And radiating efficiency can improve while can reduce cost, the realization for instrument Xiang Geng little, more portable and more practical direction provides
A kind of solution.Wherein PCR detector, which refers to, utilizes PCR (Polymerase Chain Reaction) technology i.e. polymerase
Chain reaction technology is also known as all kinds of detections of DNA isothermal DNA amplification, analysis instrument.
The Implementation Technology of the utility model is: using special design there is the cabinet of heat sinking function to detect instead of PCR
Cooling fin and radiator fan required for the normal temperature control system of instrument radiates, the heat that temperature control system generates pass through leading in heat conducting pipe
Hot liquid passes on cooling cabinet, to reduce the instrument space that cooling fin and radiator fan account for, improves radiating efficiency.
Specific technical solution: a kind of radiator for PCR detector temperature control system, including temperature control system, thermally conductive machine
Structure and cooling cabinet.
The temperature control system refers to PCR (the i.e. polymerase chain reaction of Polymerase Chain Reaction) detector
Required temperature control system and structure when operation mainly include heating and refrigerating device (such as semiconductor chilling plate) and test tube or chip
Conduct heat fixing piece etc..
The heat-conducting mechanism includes heat-conducting metal layer, heat conducting pipe and heat-conducting liquid etc., and wherein heat-conducting metal layer passes through thermally conductive
The temperature control system device that medium such as graphite flake or heat-conducting silicone grease radiate with needs is close together;Heat-conducting metal layer is included to be equipped with and be led
The cavity of hot liquid;Cavity portion is connected with heat conducting pipe, and heat-conducting metal layer inner cavity is communicated with thermally conductive lumen.
The cooling cabinet includes casing and thermal insulation layer, and wherein casing is the shell knot with heat sinking function
Structure, including radiating module, inner cavity and heat-conducting liquid;Thermal insulation layer is one layer of material with heat-proof quality for being close to interior of shell
Layer.It protects, support, fixed, anti-interference in addition to itself such as plays instrument as casing function in the radiating module part
The effects of outside, while also tool has both heat sinking function, in the case where that cannot influence itself capabilities might, is designed to radiation tooth
The shapes such as piece make it be provided simultaneously with good heat sinking function.Radiating module interior design has a cavity, inside cavity and heat conducting pipe
Cavity communicates, and heat-conducting liquid is followed in the internal cavity formation of heat-conducting metal layer, heat conducting pipe, radiating module of cabinet three parts structure
Ring, the heat in temperature control system are transferred on the radiating module of cooling cabinet by conductive fluid, and by radiating module by heat
It is scattered in external environment.
The heat-conducting mechanism can also increase a micropump on heat conducting pipe, can accelerate the circulation of thermally conductive liquid, from
And can speed up heat dissipation, heat dissipation performance is improved, satisfaction has the PCR detection of requirements at the higher level, analyzer to temperature controlled radiating system.
The cooling cabinet, radiating module (can will such as be designed to unit by designing the scattered shape of different structure
The special mark of LOGO or meaningful), radiating efficiency can be improved, moreover it is possible to increase the aesthetics and cognition degree of instrument.Simultaneously
The radiating module inner cavity of different structure can be needed to design, and by the heat-conducting liquid of circulation, the heat that need to be dissipated is uniform rapidly
Be distributed to the various pieces of cooling cabinet, to accelerate radiating rate, improve radiating efficiency.
Advantage is the utility model compared with prior art:
(1) in the case where saving special radiator and radiator fan, external environment can be come into contact in a large area using cabinet
Characteristic is quickly and effectively radiated, and relatively existing to utilize cooling fin and radiator fan technology, radiating efficiency is higher, speed
Faster, so as to improving entire instrument performance.With very strong practicability.It can be effectively reduced using case radiation simultaneously scattered
Hot device and fan are taken up space, so that detector structure is more compact, is more minimized for PCR detector and are provided one with portable
The reliable method of kind and shortcut, are widely applied for PCR detector in fields such as medical diagnosis, judicial expertise, food inspections
Provide reliable technical optimization scheme.
(2) using special design there is the cabinet of heat sinking function to replace required for the normal temperature control system heat dissipation of PCR detector
Cooling fin and radiator fan, temperature control system generate heat passed on cooling cabinet by the heat-conducting liquid in heat conducting pipe, from
And reduce the instrument space that cooling fin and radiator fan account for, radiating efficiency is improved, effectively avoids radiation processes in instrument
The possibility that portion's environment influences.
Detailed description of the invention
Fig. 1 is a kind of construction for heat radiating device schematic diagram for temperature control system in PCR detector of the utility model;
A kind of another example structure of construction for heat radiating device for temperature control system in PCR detector of Fig. 2 the utility model
Schematic diagram.
1 cooling cabinet, 11 thermal insulation layers, 12 casings, 13 under-chassis, 14 radiating modules, 2 temperature control systems, 3 heat-conducting mechanisms,
31 heat-conducting mediums, 32 heat-conducting metal layers, 33 heat conducting pipes, 34 Micropumps, 4 heat-conducting liquids.
Specific embodiment
1 and Fig. 2 is described further the content of utility model device with reference to the accompanying drawing, but the utility model is not
It is confined to following case study on implementation.
Case study on implementation 1: as shown in Figure 1, a kind of radiator for PCR detector temperature control system, including temperature control system
2, heat-conducting mechanism 3 and cooling cabinet 1.
Required temperature control system and structure when the temperature control system 2 is the operation of PCR detector, mainly include heating and refrigerating
Device and fixed structure etc..
The heat-conducting mechanism 3 includes heat-conducting metal layer 32, heat conducting pipe 33 and heat-conducting liquid 4 etc., and heat-conducting mechanism 3 is to guarantee temperature
Control system 2 operates normally and carries out heat transfer and shed.Wherein heat-conducting metal layer 32 by heat-conducting medium such as graphite flake or is led
Hot silicone grease 31 is close together with the 2 heating and refrigerating device of temperature control system to radiate is needed;Contain inner cavity in 32 layers of heat-conducting metal, leads
32 layers of thermometal are connected with heat conducting pipe 33, and 32 inner cavity of heat-conducting metal layer is communicated with 33 inner cavity of heat conducting pipe, intracavitary to have the thermally conductive of circulation
Liquid 4.The 2 heating and refrigerating device heat of temperature control system for needing to radiate goes to its intracavitary heat-conducting liquid by heat-conducting metal layer 32
In 4.
The heat-conducting liquid 4 refers to liquid transmitter such as conduction oil, water with excellent heat transfer, launch performance
Silver, liquid metal or water etc..Due to the mobility and circulation of liquid, liquid is set to have very big heat transfer area, it is easy to heat
Take away transfer.Heat-conducting liquid 4 absorbs temperature control system 2 and needs the heat that dissipates, then successively by 32 inner cavity of heat-conducting metal layer and
Heat conducting pipe 33 transfers heat on cooling cabinet, and the heat-conducting liquid 4 for shifting heat after cooling is thermally conductive using the other end
Pipe stream 33 returns in 32 inner cavity of heat-conducting metal layer, so that realizing will be quickly transferred on cooling cabinet 1 from 2 heat of temperature control system,
It recycles cooling cabinet 1 to be in large area contact with air quickly to be scattered to heat in external environment.Heat-conducting liquid 4 is led by what is be connected to
Circulation is realized in 32 inner cavity of metal layer, thermally conductive tube cavity 33,1 inner cavity of cooling cabinet, so that realizing being capable of fast transfer by heat.
In the case where being finally implemented without special radiator and radiator fan, quickly and effectively radiated.
The cooling cabinet 1 includes casing 12 and thermal insulation layer 11, and wherein casing 12 is with heat sinking function
Shell mechanism, including radiating module 14 and inner cavity have the heat-conducting liquid 4 of circulation in inner cavity;Thermal insulation layer 11 is to be close to outside cabinet
The material layer of one layer of specific heat-proof quality inside shell 12, major function are to guarantee that the heat on casing 12 can only be to air
In distribute, avoid heat transfer to instrument internal spread, thus influence the temperature control system 2 in instrument internal, instrument component and
The normal operation of experiment;Inner cavity is to facilitate thermally conductive for heat-conducting liquid 4 in the channel that cabinet inside circulates and is connected with heat conducting pipe
Heat is distributed to the various pieces of radiating module 14 by liquid 4, improves radiating efficiency, while guaranteeing that heat-conducting liquid 4 can be in instrument
Circulation inside device.
It protects, support, solid in addition to itself such as plays instrument as 1 case function of cabinet in 14 part of radiating module
Outside the effects of fixed, anti-interference, while heat sinking function is also had both, when itself function cannot be influenced, is designed to band
There are the shapes such as heat dissipation gear piece, it is made to be provided simultaneously with good heat sinking function.14 interior design of radiating module has a cavity, cavity with
Thermally conductive tube chamber communicates, heat-conducting liquid heat-conducting metal layer 32, heat conducting pipe 33,14 three parts structure of radiating module of cabinet inside
Cavity forms circulation, and the heat in temperature control system 2 is transferred on the radiating module 14 of cooling cabinet 1 by conductive fluid 4, and is passed through
Heat is scattered in external environment by radiating module 14.
Case study on implementation 2: as shown in Fig. 2, increasing a Micropump 34, energy on the basis of case study on implementation 1 according to actual needs
Enough accelerate the circulation rate of heat-conducting liquid, so as to accelerate to radiate, improves radiating efficiency.Specific as follows, one kind is examined for PCR
Survey the device of instrument temperature control system heat dissipation, including temperature control system 2, heat-conducting mechanism 3 and cooling cabinet 1.Meet to temperature controlled radiating system
There is the PCR detector of requirements at the higher level.
Required temperature control system and structure when the temperature control system 2 is the operation of PCR detector, mainly include heating and refrigerating
Device (such as semiconductor chilling plate) and fixed structure.
The heat-conducting mechanism 3 includes heat-conducting metal layer 32, heat conducting pipe 33, Micropump 34 and heat-conducting liquid 4 etc., heat-conducting mechanism 3
Heat transfer is carried out for guarantee temperature control system 2 normal operation and is shed.Wherein heat-conducting metal layer 32 passes through heat-conducting medium such as stone
Ink sheet or heat-conducting silicone grease 31 are close together with the 2 heating and refrigerating device of temperature control system to radiate is needed;32 layers of heat-conducting metal include
There is inner cavity, 32 layers of heat-conducting metal are connected with heat conducting pipe 33, and 32 inner cavity of heat-conducting metal layer is communicated with 33 inner cavity of heat conducting pipe, intracavitary to follow
The heat-conducting liquid 4 of ring.To go to its intracavitary by heat-conducting metal layer 32 for the 2 heating and refrigerating device heat of temperature control system for needing to radiate
In heat-conducting liquid 4.
The heat-conducting liquid 4 refers to liquid transmitter such as conduction oil, water with excellent heat transfer, launch performance
Silver, liquid metal or water etc..Due to the mobility of liquid, make liquid that there is very big heat transfer area, easy heat is taken away turns
It moves.Heat-conducting liquid 4 absorbs the heat that temperature control system 2 needs to dissipate, and then successively passes through 32 inner cavity of heat-conducting metal layer and heat conducting pipe
33 transfer heat on cooling cabinet, shift the heat-conducting liquid 4 of heat after cooling using other end heat conducting pipe stream 33
It returns in 32 inner cavity of heat-conducting metal layer, Micropump 34 drives heat-conducting liquid 4 constantly to recycle in several cavitys, so that realizing will be from temperature
2 heat of control system is quickly transferred on cooling cabinet 1, is recycled cooling cabinet 1 to be in large area contact with air and is quickly dissipated heat
Into external environment.Heat-conducting liquid 4 is real by 32 inner cavity of heat-conducting metal layer of connection, thermally conductive tube cavity 33,1 inner cavity of cooling cabinet
It now recycles, so that realizing being capable of fast transfer by heat.In the case where being finally implemented without special radiator and radiator fan,
Quickly and effectively radiated.A temperature for temperature control sensor detection temperature control system 2 can be used simultaneously, be sentenced using the height of temperature
Disconnected heat-conducting liquid 4 needs the speed recycled and is adjusted by Micropump 34, thus it is more efficient, reasonably carry out temperature control system
2 heat dissipations, meeting to radiate to temperature control system 2 has the PCR detector of requirements at the higher level.
The cooling cabinet 1 includes casing 12 and thermal insulation layer 11, and wherein casing 12 is with heat sinking function
Shell mechanism, including radiating module 14 and inner cavity have the heat-conducting liquid 4 of circulation in inner cavity;Thermal insulation layer 11 is to be close to outside cabinet
One layer of material layer with heat-proof quality inside shell 12, major function are to guarantee that the heat on casing 12 can only be to air
In distribute, avoid heat transfer to instrument internal spread, thus influence the temperature control system 2 in instrument internal, instrument component and
The normal operation of experiment;Inner cavity is to facilitate thermally conductive for heat-conducting liquid 4 in the channel that cabinet inside circulates and is connected with heat conducting pipe
Heat is distributed to the various pieces of radiating module 14 by liquid 4, improves radiating efficiency, while guaranteeing that heat-conducting liquid 4 can be in instrument
Circulation inside device.
It protects, support, solid in addition to itself such as plays instrument as 1 case function of cabinet in 14 part of radiating module
Outside the effects of fixed, anti-interference, while heat sinking function is also had both, when itself function cannot be influenced, is designed to band
There are the shapes such as heat dissipation gear piece, it is made to be provided simultaneously with good heat sinking function.14 interior design of radiating module has a cavity, cavity with
Thermally conductive tube chamber communicates, heat-conducting liquid heat-conducting metal layer 32, heat conducting pipe 33,14 three parts structure of radiating module of cabinet inside
Cavity forms circulation, and the heat in temperature control system 2 is transferred on the radiating module 14 of cooling cabinet 1 by conductive fluid 4, and is passed through
Heat is scattered in external environment by radiating module 14.
The cooling cabinet 1, radiating module 14 (can will be such as designed to by designing the heat dissipation shape of different structure
Unit LOGO or especially mark), radiating efficiency can be improved, moreover it is possible to increase the aesthetics of instrument and there is the effect of publicity.Together
When can according to need design different structure 14 inner cavity of radiating module, it is by the heat-conducting liquid of circulation, the heat that need to be dissipated is fast
Speed is evenly dispersed to the various pieces of cooling cabinet, to accelerate radiating rate, improves radiating efficiency.
It is capable of the heat dissipating method and its device of PCR detector temperature control system easy to accomplish in the above manner, is particularly suitable for
Miniaturization, portable PC R detection, analyzer, so that radiator portion is accounted for instrument space and be substantially reduced, and radiating efficiency can improve,
It can reduce cost simultaneously, provide a kind of solution for instrument Xiang Geng little, more portable and practicability realization.But it is above to implement
Example is only to illustrate the technical solution of the utility model, rather than its limitations;Those of ordinary skill in the art still can be to it
Technical solution is carried out to modify, and these modification it does not separate the essence of the corresponding technical solution various embodiments of the utility model
The spirit and scope of scheme.
Claims (6)
1. a kind of radiator for PCR detector temperature control system, characterized by comprising: temperature control system, heat-conducting mechanism and
Cooling cabinet;
The heat-conducting mechanism includes heat-conducting metal layer, heat conducting pipe and heat-conducting liquid;Heat-conducting metal layer is by heat-conducting medium and needs
Heating and refrigerating device is close together in the temperature control system of heat dissipation;Heat-conducting metal layer includes the cavity equipped with heat-conducting liquid, cavity
Part is connected with heat conducting pipe, and heat-conducting metal layer inner cavity is communicated with thermally conductive lumen;
The cooling cabinet includes: casing and thermal insulation layer, and casing is the shell mechanism with heat sinking function, the machine
Box enclosure includes radiating module, inner cavity and heat-conducting liquid;Thermal insulation layer is the material for being close to one layer of specific heat-proof quality of interior of shell
The bed of material.
2. a kind of radiator for PCR detector temperature control system according to claim 1, it is characterised in that: described
Heat-conducting medium is graphite flake or heat-conducting silicone grease.
3. a kind of radiator for PCR detector temperature control system according to claim 1, it is characterised in that: described
Radiating module is set as with radiation tooth plate shape.
4. a kind of radiator for PCR detector temperature control system according to claim 1, it is characterised in that: described
Radiating module interior design has cavity, and the cavity is communicated with thermally conductive tube chamber, heat-conducting liquid heat-conducting metal layer, heat conducting pipe,
The internal cavity of radiating module of cabinet three parts structure forms circulation.
5. a kind of radiator for PCR detector temperature control system according to claim 1, it is characterised in that: described
Heat-conducting mechanism is equipped with micropump on heat conducting pipe.
6. a kind of radiator for PCR detector temperature control system according to claim 1, it is characterised in that: described
Heat-conducting liquid conduction oil, mercury, liquid metal or water.
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Cited By (1)
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CN109168298A (en) * | 2018-10-18 | 2019-01-08 | 中国科学院合肥物质科学研究院 | A kind of radiator for PCR detector temperature control system |
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Publication number | Priority date | Publication date | Assignee | Title |
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CN109168298A (en) * | 2018-10-18 | 2019-01-08 | 中国科学院合肥物质科学研究院 | A kind of radiator for PCR detector temperature control system |
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