CN209508224U - A kind of magnetic frame extracting nucleic acid for paramagnetic particle method - Google Patents

A kind of magnetic frame extracting nucleic acid for paramagnetic particle method Download PDF

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Publication number
CN209508224U
CN209508224U CN201822234515.4U CN201822234515U CN209508224U CN 209508224 U CN209508224 U CN 209508224U CN 201822234515 U CN201822234515 U CN 201822234515U CN 209508224 U CN209508224 U CN 209508224U
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China
Prior art keywords
nucleic acid
accommodating chamber
magnet
wainscot
magnetic frame
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CN201822234515.4U
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Chinese (zh)
Inventor
安新
宗洁
曲峰
窦兰兰
严勇
陈超
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Suzhou Ying Ruicheng Biochemical Technology Co Ltd
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Suzhou Ying Ruicheng Biochemical Technology Co Ltd
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Abstract

The utility model discloses a kind of magnetic frames that nucleic acid is extracted for paramagnetic particle method, comprising: the supporting vertical plate extended along the vertical direction;And it is integrally fixed in the wainscot and lower wall panels of supporting vertical plate upper and lower ends respectively, wherein wainscot is horizontally extending with lower wall panels, and the upper surface of wainscot offers at least two and extends to accommodating chamber inside supporting vertical plate from top to bottom.According to the utility model, structure is simple, it is easy to operate, by the magnet for being placed with several pieces in the magnet accommodating chamber that is arranged in accommodating chamber, and accommodating chamber is divided into multiple magnet accommodating chambers, what is worked in the actual operation process is high-efficient, high to the effect of separated substance separation, and what is obtained needs object with high purity.

Description

A kind of magnetic frame extracting nucleic acid for paramagnetic particle method
Technical field
The utility model relates to magnetic frame field, in particular to a kind of magnetic frame that nucleic acid is extracted for paramagnetic particle method.
Background technique
Magnetic filtration device frame is mainly used for removing powdery, the Ferromagnetic Impurities in feed particulate material and liquid or slurry, extensively Suitable for industries such as ceramics, electric power, mining industry, plastics, chemical industry, rubber, pharmacy, food, environmental protection, pigment, dyestuff, electronics, metallurgy, When iron-containing substance passes through, by the attraction of magnetic bar, iron-containing substance is firmly adsorbed on tube wall, to guarantee equipment Intact and product safety.
Paramagnetic particle method extracts nucleic acid and biological micromolecule is used widely in biological field, and paramagnetic particle method, which extracts nucleic acid, to be had The advantages such as DNA purity is higher, sample is high-throughput.In the case where sample size is few, manual paramagnetic particle method extracts nucleic acid and then needs magnetic force Frame.Magnetic frame material type currently on the market is different, and structure is also not quite similar.
But present magnetic frame has certain problems, first, existing magnetic frame has that structure is complicated more low efficiency It the defects of lower, is very limited in practical applications.Second, causing because structure is complicated inconvenient for operation, separating effect is low, obtains The not high using effect of the articles purity arrived is also poor.
In view of this, it is really necessary to develop a kind of magnetic frame for extracting nucleic acid for paramagnetic particle method, to solve the above problems.
Utility model content
For the shortcomings of the prior art, the purpose of the utility model is to provide one kind to extract for paramagnetic particle method The magnetic frame of nucleic acid, structure is simple, easy to operate, by the magnetic for being placed with several pieces in the magnet accommodating chamber that is arranged in accommodating chamber Iron, and accommodating chamber is divided into multiple magnet accommodating chambers, and what is worked in the actual operation process is high-efficient, to separated substance point From effect it is high, what is obtained needs object purity is high, in order to realize above-mentioned purpose according to the present utility model and other advantages, Provide a kind of magnetic frame that nucleic acid is extracted for paramagnetic particle method, comprising:
The supporting vertical plate extended along the vertical direction;And
It is integrally fixed in the wainscot and lower wall panels of supporting vertical plate upper and lower ends respectively,
Wherein, wainscot and lower wall panels are horizontally extending, and the upper surface of wainscot offers at least two from upper The accommodating chamber inside supporting vertical plate is extended under.
Preferably, wainscot and lower wall panels extend horizontally outward both with respect to the front and rear sides of supporting vertical plate.
Preferably, at least two through-holes through its upper and lower surface are offered on wainscot.
Preferably, at least two locating slots are offered in lower wall panels, locating slot is oppositely arranged with through-hole in the vertical direction, Wherein, the number of locating slot and the number of through-hole are corresponding.
Preferably, spacing block is equipped in each accommodating chamber, which is separated at least two magnet for accommodating chamber and accommodates Chamber is placed at least two blocks of magnet in each magnet accommodating chamber.
Preferably, in the magnet accommodating chamber in magnet magnetization direction be perpendicular to vertical direction, each magnet Magnet magnetization direction in accommodating chamber is identical.
Preferably, through-hole places the EP pipe being adapted to therewith, and the bottom end of the EP pipe is contained in locating slot.
Preferably, wainscot and lower wall panels are symmetrical arranged about supporting vertical plate in front and back, between two neighboring accommodating chamber Offer the fabrication hole extended from top to bottom.
The utility model compared with prior art, the beneficial effect is that: structure is simple, easy to operate, by accommodating chamber Several pieces of magnet is placed in the magnet accommodating chamber of middle setting, and accommodating chamber is divided into multiple magnet accommodating chambers, in practical operation What is worked in the process is high-efficient, high to the effect of separated substance separation, and what is obtained needs object with high purity.
Detailed description of the invention
Fig. 1 is the magnetic frame three dimensional structure diagram that nucleic acid is extracted for paramagnetic particle method according to the utility model;
Fig. 2 is the left view according to the magnetic frame for extracting nucleic acid for paramagnetic particle method of the utility model;
Fig. 3 is the half-section diagram according to the magnetic frame for extracting nucleic acid for paramagnetic particle method of the utility model;
Fig. 4 is the Use Limitation fruit schematic diagram according to the magnetic frame for extracting nucleic acid for paramagnetic particle method of the utility model.
Wherein: 1- magnetic frame, 11- wainscot, 12- lower wall panels, 13- accommodating chamber, 14- through-hole, 15- locating slot, 16- technique Hole, 17- supporting vertical plate, 18- spacing block.
Specific embodiment
The following describes the utility model in further detail with reference to the accompanying drawings, the aforementioned and other mesh of the utility model , features, aspects and advantages will be apparent, to enable those skilled in the art's refer to the instruction text real accordingly It applies.In the accompanying drawings, for clarity, shape and size can be amplified, and identical attached drawing mark will be used in all figures Note is to indicate the same or similar component.In the following description, such as center, thickness, height, length, front, back, rear portion, The words such as the left side, the right, top, bottom, top, lower part are to be based on the orientation or positional relationship shown in the drawings.Particularly, " high Degree " is equivalent to size from the top to the bottom, and " width " is equivalent to size from left to right, and " depth " is equivalent to be arrived in the past Size afterwards.These relative terms are to be not intended to need specifically to be orientated for convenience and usually.Be related to attachment, Connection etc. term (for example, " connection " and " attachment ") refer to these structures pass through intermediate structure directly or indirectly to one another fixation or The relationship of attachment and movable or rigidly attached or relationship, unless otherwise clearly stating.
Referring to Fig.1-3, the magnetic frame 1 for paramagnetic particle method extraction nucleic acid includes:
The supporting vertical plate 17 extended along the vertical direction;And
It is integrally fixed in the wainscot 11 and lower wall panels 12 of 17 upper and lower ends of supporting vertical plate respectively,
Wherein, wainscot 11 is horizontally extending with lower wall panels 12, and the upper surface of wainscot 11 offers at least two A accommodating chamber 13 extended to inside supporting vertical plate 17 from top to bottom.
Front and rear sides of the wainscot 11 with lower wall panels 12 both with respect to supporting vertical plate 17 extend horizontally outward.
At least two through-holes 14 through its upper and lower surface are offered on wainscot 11.
At least two locating slots 15 are offered in lower wall panels 12, locating slot 15 is opposite with through-hole 14 in the vertical direction to be set It sets, wherein the number of locating slot 15 is corresponding with the number of through-hole 14.
Spacing block 18 is equipped in each accommodating chamber 13, which is separated at least two magnet for accommodating chamber 13 and accommodates Chamber is placed at least two blocks of magnet in each magnet accommodating chamber.
Magnet magnetization direction in the magnet accommodating chamber is perpendicular to vertical direction, in each magnet accommodating chamber Magnet magnetization direction it is identical.
Through-hole 14 places the EP pipe being adapted to therewith, and the bottom end of the EP pipe is contained in locating slot 15, and the EP pipe is The heparin tube of 15ml.
Wainscot 11 and lower wall panels 12 are symmetrical arranged about supporting vertical plate 17 in front and back, between two neighboring accommodating chamber 13 Offer the fabrication hole 16 extended from top to bottom.
In use, it will need to carry out lock out operation test tube to put into through-hole 14, and by the bottom end of test tube to certainly Position slot 15, because through-hole 14 and the central axis of location hole 15 coincide, the test tube put at this time is vertical and horizontal, Bu Huiyin To place inclination, the Beads enrichment for causing magnet to set test tube interior quartile is insufficient, because point having in accommodating chamber 13 several A magnet accommodating chamber, is placed at least two blocks of magnet in each magnet accommodating chamber, the magnetized direction of every block of magnet be all it is consistent, Therefore the magnetic force generated, which is superimposed, to be increased, and can be carried out effectively separation, the distribution of multiple magnet to the magnetic bead of test tube from top to bottom Good to the effect of Beads enrichment also thorough, through-hole 14 is located at 13 two sides of accommodating chamber, therefore magnet can be to the test tube of two sides In magnetic bead separate simultaneously, to the mask work of small lot, the efficiency of mask work is greatly improved at this time, and of the invention Magnetic frame 1 be rendered as drum structure, structure is simple, easy to operate during operating with.
Number of devices and treatment scale described herein are the explanations for simplifying the utility model.To the utility model Application, modifications and variations will be readily apparent to persons skilled in the art.
Although the embodiments of the present invention have been disclosed as above, it is not limited in institute in specification and embodiments Column use, it can be applied to various fields suitable for the present invention completely, for those skilled in the art, can Easily realize other modification, therefore without departing from the general concept defined in the claims and the equivalent scope, this is practical It is novel to be not limited to specific details and legend shown and described herein.

Claims (8)

1. a kind of magnetic frame (1) for extracting nucleic acid for paramagnetic particle method, comprising:
The supporting vertical plate (17) extended along the vertical direction;And
It is integrally fixed in the wainscot (11) and lower wall panels (12) of supporting vertical plate (17) upper and lower ends respectively,
Wherein, wainscot (11) and lower wall panels (12) are horizontally extending, and the upper surface of wainscot (11) offers at least Two extend to the internal accommodating chamber (13) of supporting vertical plate (17) from top to bottom.
2. as described in claim 1 for paramagnetic particle method extract nucleic acid magnetic frame (1), which is characterized in that wainscot (11) with Lower wall panels (12) extend horizontally outward both with respect to the front and rear sides of supporting vertical plate (17).
3. the magnetic frame (1) of nucleic acid is extracted for paramagnetic particle method as described in claim 1, which is characterized in that on wainscot (11) Offer at least two through-holes (14) through its upper and lower surface.
4. the magnetic frame (1) of nucleic acid is extracted for paramagnetic particle method as described in claim 1, which is characterized in that in lower wall panels (12) It offers at least two locating slots (15), locating slot (15) is oppositely arranged with through-hole (14) in the vertical direction, wherein locating slot (15) number is corresponding with the number of through-hole (14).
5. the magnetic frame (1) of nucleic acid is extracted for paramagnetic particle method as described in claim 1, which is characterized in that each accommodating chamber (13) spacing block (18) are equipped in, which is separated at least two magnet accommodating chambers, Mei Gesuo for accommodating chamber (13) It states and is placed at least two blocks of magnet in magnet accommodating chamber.
6. the magnetic frame (1) of nucleic acid is extracted for paramagnetic particle method as claimed in claim 5, which is characterized in that the magnet accommodates Perpendicular to vertical direction, the magnet magnetization direction in each magnet accommodating chamber is identical for magnet magnetization direction in intracavitary.
7. the magnetic frame (1) of nucleic acid is extracted for paramagnetic particle method as described in claim 1, which is characterized in that through-hole (14) is placed The EP pipe being adapted to therewith, the bottom end of the EP pipe is contained in locating slot (15).
8. as described in claim 1 for paramagnetic particle method extract nucleic acid magnetic frame (1), which is characterized in that wainscot (11) and Lower wall panels (12) about supporting vertical plate (17) in front and back be symmetrical arranged, offered between two neighboring accommodating chamber (13) from up to The fabrication hole (16) of lower extension.
CN201822234515.4U 2018-12-28 2018-12-28 A kind of magnetic frame extracting nucleic acid for paramagnetic particle method Active CN209508224U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201822234515.4U CN209508224U (en) 2018-12-28 2018-12-28 A kind of magnetic frame extracting nucleic acid for paramagnetic particle method

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Application Number Priority Date Filing Date Title
CN201822234515.4U CN209508224U (en) 2018-12-28 2018-12-28 A kind of magnetic frame extracting nucleic acid for paramagnetic particle method

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI830144B (en) * 2021-10-19 2024-01-21 英華達股份有限公司 Selection device and magnetic rack

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI830144B (en) * 2021-10-19 2024-01-21 英華達股份有限公司 Selection device and magnetic rack

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