CN209481651U - A kind of drug resistant mutant genes of mycobacterium tuberculosis extraction element - Google Patents

Abstract

The utility model provides a kind of drug resistant mutant genes of mycobacterium tuberculosis extraction element, including shielded box, Double-layer test tube frame, station, centrifuge, mechanical arm and container etc., material to be extracted is fitted into the container, the container is placed in the Double-layer test tube frame, container described in the mechanical arm automatic clamping extracts.Drug resistant mutant genes of mycobacterium tuberculosis extraction element provided by the utility model, all gene extraction process carry out in the shielded box, it can be good at completely cutting off external influence, guarantee the quality of extraction gene, the mechanical arm can take the container for filling material to be extracted from the Double-layer test tube frame automatically according to certain process, then certain operation is carried out on the station, gene in material to be extracted is extracted, it is not required to the participation of very important person in the process, liberate manpower, medical worker experimenter having time is set to carry out other work, improve working efficiency.

Description

A kind of drug resistant mutant genes of mycobacterium tuberculosis extraction element

Technical field

The utility model relates to area of medical devices more particularly to a kind of drug resistant mutant genes of mycobacterium tuberculosis to extract dress It sets.

Background technique

Extract drug resistant mutant genes of mycobacterium tuberculosis need through taking morning phlegm, adding sodium hydroxide solution liquefaction morning phlegm, from The heart stays precipitating, precipitating to be cleaned with physiological saline repeatedly except supernatant, is centrifuged and removes supernatant, DNA extracting solution is added, is centrifuged and removes supernatant The step of.

Under existence conditions, the above process needs medical worker experimenter in aseptic experiment room by certain experiment instrument The progress of device manual operations step by step, troublesome in poeration, inefficiency, drug resistance of Mycobacterium tuberculosis mutation provided by the utility model Gene extraction element can proceed as described above automatically, liberate manpower, medical worker experimenter having time is made to carry out other works Make, improves working efficiency.

Utility model content

In order to solve the above technical problems, the utility model provides a kind of drug resistant mutant genes of mycobacterium tuberculosis extraction dress It sets.

A kind of drug resistant mutant genes of mycobacterium tuberculosis extraction element, the shielded box including side setting opening, wherein

The hinged hermatic door in side of the isolation box opening, the side wall of the shielded box of hermatic door described in face, which is arranged, to be slided Rail, be slidably connected on the sliding rail mechanical arm, sets gradually centrifuge, operation along the direction of the sliding rail in the shielded box Platform and Double-layer test tube frame place container on the Double-layer test tube frame；

The station is in " Contraband " shape structure, and " Contraband " the shape structure includes waste water tank and inverted L shape supporting table, described L shape supporting table is fixed on the top of the waste water tank, and multiple kits, the kit is arranged in the top of the L shape supporting table Top filling opening is set, the bottom of the kit is arranged outlet tube, is fixed with tube manipulation mechanism in the L shape supporting table And extraction mechanism.

Preferably, the container includes liquid separation test tube and centrifuge tube, and the liquid separation test tube includes funnel shaped test tube mouth, examination Tube body, inductive switch and dropper, the test tube mouth are set to the top of the test tube body, and the dropper is connected to the test tube body Bottom, the inductive switch is set on the dropper, the liquid separation test tube is placed in the upper layer of the Double-layer test tube frame, described Test tube mouth is connected to the test tube receiving hole of the Double-layer test tube frame, and the centrifuge tube includes valve protection cap and centrifugation tube body, the centrifugation There is circular protrusion on the outside of tube body, the valve protection cap is articulated with the nozzle of the centrifugation tube body, and there is plate protrusion in the valve protection cap side, Semi-circular groove is arranged in plate protrusion two sides, and the centrifuge tube is placed in the lower layer of the Double-layer test tube frame, described cyclic annular prominent The test tube receiving hole for being connected in the Double-layer test tube frame is acted, scale is set on the test tube body and the centrifugation tube body.

Preferably, the tube manipulation mechanism include the first telescopic arm, first motor, sub- connector, female connector, rotating bar, Bristle, stirring sheet, rotary table and the second motor, first telescopic arm and second motor are fixed in the L shape branch side by side It supports on platform, the fixed rotary table of the output shaft of second motor, the bottom surface of the rotary table is arranged the first plug along edge, runs through First plug and the rotary table are rotatablely connected multiple rotating bars, and the brush is arranged in the bottom of rotating bar described in half Hair, the bottom of the other half rotating bar are arranged the stirring sheet, the fixed female connector in the top of the rotating bar, and described the The fixed first motor in the bottom of one telescopic arm, the fixed sub- connector of the output shaft of the first motor, the sub- connector Movement is plugged in the female connector.

Preferably, the extraction mechanism includes the second telescopic arm, pumping cylinder, push rod, piston, swivel becket, pipette, driving Wheel, third motor and L shape connecting rod, second telescopic arm and the L shape connecting rod are fixed in the L shape side by side and support Platform, the fixed push rod in the bottom of second telescopic arm, the fixed piston in the bottom of the push rod, the piston sliding connect It is connected to the pumping cylinder, the bottom of the pumping cylinder is connected to the pipette, has external screw thread, the L shape on the outside of the pipette The top of cross bar one end of connecting rod is rotatablely connected the swivel becket, the second plug is arranged in bottom, pass through the cross bar with it is described Snorkel is arranged in second plug, and internal screw thread is arranged in the inner wall of the swivel becket, and the pipette passes through the swivel becket and successively passes through The cross bar and second plug are worn, and the external thread bolt connection, in the internal screw thread, the outside of the swivel becket contradicts institute Driving wheel is stated, the driving wheel is fixed on the third motor, and the third motor is fixed on the vertical bar of the L shape connecting rod On.

Preferably, the centrifuge includes the 4th motor, fixed station, fixed plate and shell, and the shell is placed in institute The bottom surface of shielded box to be stated, the 4th motor is fixed in the shell, the output shaft of the 4th motor fixes the fixed station, Jack is arranged in the fixed plate in hinged multiple fixed plates on the fixed station, and the centrifuge tube is plugged in the jack, The circular protrusion is connected on the jack.

Preferably, the mechanical arm includes sliding block, three connecting rods, two joints and work hand, three connecting rods Between connected by the joint, and be rotatablely connected between the joint and the connecting rod, the connecting rod positioned at both ends is distinguished The sliding block and the work hand are set, and the sliding block is slidably connected to the sliding rail, the sliding block opposite with the sliding rail Side is rotatablely connected electric roller, the clamping container of work hand.

Preferably, the work hand includes the fixing seat in truncated rectangular pyramids shape, and clamping jaw is arranged in the end of the fixing seat, described Clamping jaw includes two arc clips being oppositely arranged, one of them described arc clip is fixed on the fixing seat, another institute The arc clip hingedly fixing seat is stated, the middle part of the fixing seat is rotatablely connected L-shaped movable claw, the movable claw activity It is connected in semicircle groove.

Preferably, the joint includes the first link block, drive shaft and the second link block, and first link block passes through institute State hinged second link block of drive shaft.

Compared with the relevant technologies, drug resistant mutant genes of mycobacterium tuberculosis extraction element provided by the utility model has It is following the utility model has the advantages that

Drug resistant mutant genes of mycobacterium tuberculosis extraction element provided by the utility model, all gene extraction process are equal It is carried out in the shielded box, can be good at completely cutting off external influence, guarantee the quality for extracting gene, the mechanical arm energy It is enough to take the container for filling material to be extracted from the Double-layer test tube frame automatically according to certain process, then in the behaviour Make to carry out certain operation on platform, the gene in material to be extracted is extracted, be not required to the participation of very important person in the process, liberates people Power makes medical worker experimenter having time carry out other work, improves working efficiency.

Detailed description of the invention

Fig. 1 is a kind of preferred embodiment of drug resistant mutant genes of mycobacterium tuberculosis extraction element provided by the utility model Structural schematic diagram；

Fig. 2 is the structural schematic diagram of station shown in FIG. 1；

Fig. 3 is the structural schematic diagram of tube manipulation mechanism shown in Fig. 2；

Fig. 4 is the structural schematic diagram of extraction mechanism shown in Fig. 2；

Fig. 5 is the structure sectional view of extraction mechanism shown in Fig. 4；

Fig. 6 is the structural schematic diagram of centrifuge shown in FIG. 1；

Fig. 7 is the structural schematic diagram of container shown in FIG. 1；

Fig. 8 is the structural schematic diagram of mechanical arm shown in FIG. 1；

Fig. 9 is the structure machine connection schematic diagram of extraction mechanism under another embodiment.

Figure label: 1, shielded box, 11, hermatic door, 2, sliding rail, 3, mechanical arm, 31, sliding block, 311, electric roller, 32, connecting rod, 33, joint, the 331, first link block, 332, drive shaft, the 333, second link block, 34, work hand, 341, activity Pawl, 342, clamping jaw, 4, centrifuge, the 41, the 4th motor, 42, fixed station, 43, fixed bin, 431, jack, 5, station, 51, examination Agent box, 511, filling opening, 512, outlet tube, 52, waste water tank, 6, Double-layer test tube frame, 7, tube manipulation mechanism, 71, first is flexible Arm, 72, first motor, 73, sub- connector, 74, female connector, 75, rotating bar, 76, bristle, 77 stirring sheets, 78, rotary table, 781, One plug, the 79, second motor, 8, extraction mechanism, the 81, second telescopic arm, 82, pumping cylinder, 83, push rod, 84, piston, 85, turn Rotating ring, 86, pipette, 861, external screw thread, 87, driving wheel, 88, third motor, 89, L shape connecting rod, the 891, second plug, 892, snorkel, 9, container, 91, liquid separation test tube, 911, test tube mouth, 912, test tube body, 913, inductive switch, 914, dropper, 92, centrifuge tube, 921, valve protection cap, 922, centrifugation tube body.

Specific embodiment

The utility model is described in further detail with embodiment with reference to the accompanying drawing.

Fig. 1, Fig. 2, Fig. 3, Fig. 4, Fig. 5, Fig. 6, Fig. 7, Fig. 9 and Fig. 9 are please referred to, wherein Fig. 1 is the utility model A kind of structural schematic diagram of preferred embodiment of the drug resistant mutant genes of mycobacterium tuberculosis extraction element of offer；Fig. 2 is Fig. 1 institute The structural schematic diagram of the station shown；Fig. 3 is the structural schematic diagram of tube manipulation mechanism shown in Fig. 2；Fig. 4 is shown in Fig. 2 The structural schematic diagram of extraction mechanism；Fig. 5 is the structure sectional view of extraction mechanism shown in Fig. 4；Fig. 6 is centrifuge shown in FIG. 1 Structural schematic diagram；Fig. 7 is the structural schematic diagram of container shown in FIG. 1；Fig. 8 is the structural representation of mechanical arm shown in FIG. 1 Figure；Fig. 9 is the structure machine connection schematic diagram of extraction mechanism under another embodiment.

Scheme 1:

A kind of drug resistant mutant genes of mycobacterium tuberculosis extraction element, including side setting opening shielded box 1, it is described every From the hinged hermatic door 11 in side that case 1 is open, the hermatic door 11 is closed together in the shielded box 1, hermatic door described in face Sliding rail 2 is arranged in the side wall of 11 shielded box 1, and the sliding rail 2 is horizontally disposed, and be slidably connected mechanical arm on the sliding rail 2 3。

The mechanical arm 3 includes 32, two, the connecting rod joint 33 of sliding block 31, three and work hand 34, three companies It is connected between bar 32 by the joint 33, the joint 33 includes the first link block 331, drive shaft 332 and the second link block 333, first link block 331 passes through hinged second link block 333 of the drive shaft 332, first link block 331 360 ° of controllable rotaries, first link block 331 and second link block can be achieved between second link block 333 The 333 rotation connection connecting rods 32, between first link block 331 and the connecting rod 32, second link block 333 and institute It states and 360 ° of controllable rotaries can be achieved between connecting rod 32, the sliding block 31 and institute is respectively set in the connecting rod 32 positioned at both ends Work hand 34 is stated, the sliding block 31 is slidably connected to the sliding rail 2, the sliding block 31 side rotation opposite with the sliding rail 2 Electric roller 311, the clamping container 9 of work hand 34 are connected, the work hand 34 includes the fixing seat in truncated rectangular pyramids shape, Clamping jaw 342 is arranged in the end of the fixing seat, and the clamping jaw 342 includes two arc clips being oppositely arranged, one of institute It states arc clip and is fixed on the fixing seat, the hinged fixing seat of another described arc clip is articulated with the institute of fixing seat It states arc clip and is able to rotate the arc clip for contradicting and being fixed on the fixing seat, so that the clamping jaw 342 can press from both sides The container 9 is held, the middle part of the fixing seat is rotatablely connected L-shaped movable claw 341, and the movable claw 341 being capable of active card It is connected to semicircle groove, and pushes the plate protrusion, to open or be closed the valve protection cap 921.

Centrifuge 4, station 5 and Double-layer test tube frame 6 are set gradually in the shielded box 1, on the Double-layer test tube frame 6 Place container 9, wherein

The container 9 includes liquid separation test tube 91 and centrifuge tube 92, and the liquid separation test tube 91 includes funnel shaped test tube mouth 911, test tube body 912, inductive switch 913 and dropper 914, the test tube mouth 911 are set to the top of the test tube body 912, The dropper 914 is connected to the bottom of the test tube body 912, and the inductive switch 913, the liquid separation are arranged on the dropper 914 Test tube 91 is placed in the upper layer of the Double-layer test tube frame 6, and the bottom of the test tube mouth 911 is connected to the Double-layer test tube frame 6 Test tube receiving hole, the centrifuge tube 92 include valve protection cap 921 and centrifugation tube body 922, and there is ring-type in the outside of the centrifugation tube body 922 Protrusion, the valve protection cap 921 are articulated with the nozzle of the centrifugation tube body 922, and there are plate protrusion, the plate in 921 side of valve protection cap Semi-circular groove is arranged in shape protrusion two sides, and the centrifuge tube 92 is placed in the lower layer of the Double-layer test tube frame 6, the circular protrusion card It is connected to the test tube receiving hole of the Double-layer test tube frame 6, scale is set on the test tube body 912 and the centrifugation tube body 922.

As shown in Fig. 2, the station 5 is in " Contraband " shape structure, the opening of " Contraband " the shape structure towards the sliding rail 2, " Contraband " the shape structure is made of waste water tank 52 and inverted L shape supporting table, and the L shape supporting table is fixed on the waste water tank Multiple kits 51 are arranged in 52 top, the top of the L shape supporting table, and filling opening is arranged in the top of the kit 51 511, outlet tube 512 is arranged in the bottom of the kit 51, and the outlet tube 512 extends through the top of the L shape supporting table To between the waste water tank 52 and the L shape supporting table, it is provided with automatic switch on the outlet tube 512, it can be controlled automatic Outlet tube 512 described in either on or off control the outflow of the drug in the kit 51, are fixed with examination in the L shape supporting table Pipe operating mechanism 7 and extraction mechanism 8.

As shown in figure 3, the tube manipulation mechanism 7 connects including the first telescopic arm 71, first motor 72, sub- connector 73, mother First 74, rotating bar 75, bristle 76, stirring sheet 77, rotary table 78 and the second motor 79, first telescopic arm 71 and described second Motor 79 is fixed in side by side in the L shape supporting table, the fixed rotary table 78 of the output shaft of second motor 79, the circle The first plug 781 is arranged along edge in the bottom surface of platform 78, is rotatablely connected multiple institutes with the rotary table 78 through first plug 781 Rotating bar 75 is stated, the bristle 76, the bottom setting of the other half rotating bar 75 is arranged in the bottom of rotating bar 75 described in half The stirring sheet 77, the fixed female connector 74 in the top of the rotating bar 75, the fixed institute in the bottom of first telescopic arm 71 First motor 72, the fixed sub- connector 73 of the output shaft of the first motor 72 are stated, the sub- movement of connector 73 is plugged in institute State female connector 74.

As shown in Figure 4 and 5, the extraction mechanism 8 includes the second telescopic arm 81, pumping cylinder 82, push rod 83, piston 84, swivel becket 85, pipette 86, driving wheel 87, third motor 88 and L shape connecting rod 89, second telescopic arm 81 and institute It states L shape connecting rod 89 and is fixed in the L shape supporting table, the fixed push rod 83 in the bottom of second telescopic arm 81, institute side by side The fixed piston 84 in bottom of push rod 83 is stated, the piston 84 is slidably connected to the pumping cylinder 82, the pumping cylinder 82 Bottom is connected to the pipette 86, has external screw thread 861 on the outside of the pipette 86, cross bar one end of the L shape connecting rod 89 Top is rotatablely connected the swivel becket 85, the second plug 891 is arranged in bottom, sets across the cross bar and second plug 891 Snorkel 892 is set, internal screw thread is arranged in the inner wall of the swivel becket 85, and the pipette passes through the swivel becket 85 and sequentially passes through institute Cross bar and second plug 891 are stated, and the external screw thread 861 is bolted in the internal screw thread, the outside of the swivel becket 85 is supported The driving wheel 87 is touched, the driving wheel 87 is fixed on the third motor 88, and the third motor 88 is fixed on the L shape and connects On the vertical bar of extension bar 89, in specific implementation process, multiple extraction mechanisms 8 are fixed in the L shape supporting table.

The centrifuge 4 includes the 4th motor 41, fixed station 42, fixed plate 43 and shell, and the shell is placed in institute The bottom surface of shielded box 1 is stated, fixes the 4th motor 41 in the shell, described in the output shaft of the 4th motor 41 is fixed Fixed station 42, hinged multiple fixed plates 43 on the fixed station 42 are arranged jack 431 in the fixed plate 43, it is described from Heart pipe 92 is plugged in the jack 431, and the circular protrusion is connected on the jack 431.

Scheme 2:

A kind of drug resistant mutant genes of mycobacterium tuberculosis extraction element, including side setting opening shielded box 1, it is described every From the hinged hermatic door 11 in side that case 1 is open, the hermatic door 11 is closed together in the shielded box 1, hermatic door described in face Sliding rail 2 is arranged in the side wall of 11 shielded box 1, and the sliding rail 2 is horizontally disposed, and be slidably connected mechanical arm on the sliding rail 2 3。

The mechanical arm 3 includes 32, two, the connecting rod joint 33 of sliding block 31, three and work hand 34, three companies It is connected between bar 32 by the joint 33, the joint 33 includes the first link block 331, drive shaft 332 and the second link block 333, first link block 331 passes through hinged second link block 333 of the drive shaft 332, first link block 331 360 ° of controllable rotaries, first link block 331 and second link block can be achieved between second link block 333 The 333 rotation connection connecting rods 32, between first link block 331 and the connecting rod 32, second link block 333 and institute It states and 360 ° of controllable rotaries can be achieved between connecting rod 32, the sliding block 31 and institute is respectively set in the connecting rod 32 positioned at both ends Work hand 34 is stated, the sliding block 31 is slidably connected to the sliding rail 2, the sliding block 31 side rotation opposite with the sliding rail 2 Electric roller 311, the clamping container 9 of work hand 34 are connected, the work hand 34 includes the fixing seat in truncated rectangular pyramids shape, Clamping jaw 342 is arranged in the end of the fixing seat, and the clamping jaw 342 includes two arc clips being oppositely arranged, one of institute It states arc clip and is fixed on the fixing seat, the hinged fixing seat of another described arc clip is articulated with the institute of fixing seat It states arc clip and is able to rotate the arc clip for contradicting and being fixed on the fixing seat, so that the clamping jaw 342 can press from both sides The container 9 is held, the middle part of the fixing seat is rotatablely connected L-shaped movable claw 341, and the movable claw 341 being capable of active card It is connected to semicircle groove, and pushes the plate protrusion, to open or be closed the valve protection cap 921.

Centrifuge 4, station 5 and Double-layer test tube frame 6 are set gradually in the shielded box 1, on the Double-layer test tube frame 6 Place container 9, wherein

The container 9 includes liquid separation test tube 91 and centrifuge tube 92, and the liquid separation test tube 91 includes funnel shaped test tube mouth 911, test tube body 912, inductive switch 913 and dropper 914, the test tube mouth 911 are set to the top of the test tube body 912, The dropper 914 is connected to the bottom of the test tube body 912, and the inductive switch 913, the liquid separation are arranged on the dropper 914 Test tube 91 is placed in the upper layer of the Double-layer test tube frame 6, and the bottom of the test tube mouth 911 is connected to the Double-layer test tube frame 6 Test tube receiving hole, the centrifuge tube 92 include valve protection cap 921 and centrifugation tube body 922, and there is ring-type in the outside of the centrifugation tube body 922 Protrusion, the valve protection cap 921 are articulated with the nozzle of the centrifugation tube body 922, and there are plate protrusion, the plate in 921 side of valve protection cap Semi-circular groove is arranged in shape protrusion two sides, and the centrifuge tube 92 is placed in the lower layer of the Double-layer test tube frame 6, the circular protrusion card It is connected to the test tube receiving hole of the Double-layer test tube frame 6, scale is set on the test tube body 912 and the centrifugation tube body 922.

As shown in Fig. 2, the station 5 is in " Contraband " shape structure, the opening of " Contraband " the shape structure towards the sliding rail 2, " Contraband " the shape structure is made of waste water tank 52 and inverted L shape supporting table, and the L shape supporting table is fixed on the waste water tank Multiple kits 51 are arranged in 52 top, the top of the L shape supporting table, and filling opening is arranged in the top of the kit 51 511, outlet tube 512 is arranged in the bottom of the kit 51, and the outlet tube 512 extends through the top of the L shape supporting table To between the waste water tank 52 and the L shape supporting table, it is provided with automatic switch on the outlet tube 512, it can be controlled automatic Outlet tube 512 described in either on or off control the outflow of the drug in the kit 51, are fixed with examination in the L shape supporting table Pipe operating mechanism 7.

As shown in figure 3, the tube manipulation mechanism 7 connects including the first telescopic arm 71, first motor 72, sub- connector 73, mother First 74, rotating bar 75, bristle 76, stirring sheet 77, rotary table 78 and the second motor 79, first telescopic arm 71 and described second Motor 79 is fixed in side by side in the L shape supporting table, the fixed rotary table 78 of the output shaft of second motor 79, the circle The first plug 781 is arranged along edge in the bottom surface of platform 78, is rotatablely connected multiple institutes with the rotary table 78 through first plug 781 Rotating bar 75 is stated, the bristle 76, the bottom setting of the other half rotating bar 75 is arranged in the bottom of rotating bar 75 described in half The stirring sheet 77, the fixed female connector 74 in the top of the rotating bar 75, the fixed institute in the bottom of first telescopic arm 71 First motor 72, the fixed sub- connector 73 of the output shaft of the first motor 72 are stated, the sub- movement of connector 73 is plugged in institute State female connector 74.

As shown in Fig. 4, Fig. 5 and Fig. 9, the extraction mechanism 8 includes the second telescopic arm 81, pumping cylinder 82, push rod 83, lives Plug 84, swivel becket 85, pipette 86, driving wheel 87, third motor 88 and L shape connecting rod 89, second telescopic arm 81 are solid Due to the L shape supporting table, electromagnet is arranged in the bottom of second telescopic arm 81, and irony is arranged in the top of the push rod 83 Attachment cap, the electromagnet can attachment cap described in the magnetic of hole, so that second telescopic arm 81 and the push rod 83 is fixed, The fixed piston 84 in the bottom of the push rod 83, the piston 84 are slidably connected to the pumping cylinder 82, the pumping cylinder 82 Bottom be connected to the pipette 86, have external screw thread 861, cross bar one end of the L shape connecting rod 89 on the outside of the pipette 86 Top be rotatablely connected the swivel becket 85, the second plug 891 is arranged in bottom, pass through the cross bar and second plug 891 Snorkel 892 is set, and internal screw thread is arranged in the inner wall of the swivel becket 85, and the pipette passes through the swivel becket 85 and sequentially passes through The cross bar and second plug 891, and the external screw thread 861 is bolted in the internal screw thread, the outside of the swivel becket 85 The driving wheel 87 is contradicted, the driving wheel 87 is fixed on the third motor 88, and the third motor 88 is fixed on the L shape On the vertical bar of connecting rod 89, and the vertical bar of the L shape connecting rod 89 is fixed on the motor control by the L shape supporting table is arranged in Disk on, be arranged on the disk it is multiple be equipped with the L shape connecting rod 89.

The centrifuge 4 includes the 4th motor 41, fixed station 42, fixed plate 43 and shell, and the shell is placed in institute The bottom surface of shielded box 1 is stated, fixes the 4th motor 41 in the shell, described in the output shaft of the 4th motor 41 is fixed Fixed station 42, hinged multiple fixed plates 43 on the fixed station 42 are arranged jack 431 in the fixed plate 43, it is described from Heart pipe 92 is plugged in the jack 431, and the circular protrusion is connected on the jack 431.

The use principle of drug resistant mutant genes of mycobacterium tuberculosis extraction element provided by the utility model is as follows:

When the drug resistant mutant genes of mycobacterium tuberculosis extraction element is installed, extracted by being added in the kit Drug needed for gene, adds material to be extracted in the liquid separation test tube 91, and the mechanical arm 3 passes through the clamping jaw 342 The liquid separation test tube 91 is clamped from the Double-layer test tube frame 6, is moved at the station 5, is directed at the outlet tube 512, The automatic switch controlled on the corresponding kit 51 adds reagent into the liquid separation test tube 91, and preliminary treatment waits mentioning It draws materials, the liquid separation test tube 91 is put back to the Double-layer test tube frame 6 by the mechanical arm 3 after the completion of processing, at this time the drop Pipe 914 is directed at the oral area of the centrifuge tube 92, opens the inductive switch 913, and 91 subnatant of liquid separation test tube is added to In the centrifuge tube 92, when upper layer floated the inductive switch 913, the inductive switch can perceive at once and close institute State dropper 914.

The mechanical arm 3 clamps the centrifuge tube 92 and adds drug at the station 5, and grasps by the test tube After the stirring for making the stirring sheet 77 in mechanism 7, arrives at the centrifuge 4, the centrifuge tube 92 is placed in the fixation On platform 42, the valve protection cap 921 is covered using the movable claw 341 and is closed, the centrifuge 4 is opened and is centrifuged, it is after the completion, described Mechanical arm 3 clamps the centrifuge tube 92, is opened the valve protection cap 921 using the movable claw 341, will be in the centrifuge tube Supernatant is sucked out using the extraction mechanism 8, and lower section precipitating is gene.

Drug resistant mutant genes of mycobacterium tuberculosis extraction element provided by the utility model, all gene extraction process are equal It is carried out in the shielded box 1, can be good at completely cutting off external influence, guarantee the quality for extracting gene, the mechanical arm 3 The container 9 for filling material to be extracted can be taken from the Double-layer test tube frame 6 automatically according to certain process, then in institute It states and carries out certain operation on station 5, the gene in material to be extracted is extracted, be not required to the participation of very important person in the process, Manpower is liberated, medical worker experimenter having time is made to carry out other work, improves working efficiency.

The above description is only the embodiments of the present invention, and therefore it does not limit the scope of the patent of the utility model, all Equivalent structure or equivalent flow shift made based on the specification and figures of the utility model, is applied directly or indirectly in Other relevant technical fields, are also included in the patent protection scope of the utility model.

Claims (8)

1. a kind of drug resistant mutant genes of mycobacterium tuberculosis extraction element, which is characterized in that the isolation including side setting opening Case (1), wherein

The hinged hermatic door in side (11) of the shielded box (1) opening, the shielded box (1) of hermatic door (11) described in face Sliding rail (2) are arranged in side wall, are slidably connected mechanical arm (3) on the sliding rail (2), along the sliding rail (2) in the shielded box (1) Direction set gradually centrifuge (4), station (5) and Double-layer test tube frame (6), place and hold on the Double-layer test tube frame (6) Device (9)；

The station (5) is in " Contraband " shape structure, and " Contraband " the shape structure includes waste water tank (52) and inverted L shape supporting table, The L shape supporting table is fixed on the top of the waste water tank (52), and multiple kits are arranged in the top of the L shape supporting table (51), filling opening (511) are arranged in the top of the kit (51), and outlet tube (512) are arranged in the bottom of the kit (51), Tube manipulation mechanism (7) and extraction mechanism (8) are fixed in the L shape supporting table.

2. drug resistant mutant genes of mycobacterium tuberculosis extraction element according to claim 1, which is characterized in that the container It (9) include liquid separation test tube (91) and centrifuge tube (92), the liquid separation test tube (91) includes funnel shaped test tube mouth (911), test tube Body (912), inductive switch (913) and dropper (914), the test tube mouth (911) are set to the top of the test tube body (912) Portion, the dropper (914) are connected to the bottom of the test tube body (912), the inductive switch are arranged on the dropper (914) (913), the liquid separation test tube (91) is placed in the upper layer of the Double-layer test tube frame (6), and the test tube mouth (911) is connected to described The test tube receiving hole of Double-layer test tube frame (6), the centrifuge tube (92) include valve protection cap (921) and centrifugation tube body (922), the centrifugation There is circular protrusion on the outside of tube body (922), the valve protection cap (921) is articulated with the nozzle of centrifugation tube body (922), the valve protection cap (921) there is plate protrusion in side, and semi-circular groove is arranged in plate protrusion two sides, and the centrifuge tube (92) is placed in the bilayer The lower layer of rack for test tube (6), the circular protrusion are connected in the test tube receiving hole of the Double-layer test tube frame (6), the test tube body (912) and scale is set on the centrifugation tube body (922).

3. drug resistant mutant genes of mycobacterium tuberculosis extraction element according to claim 1, which is characterized in that the test tube Operating mechanism (7) include the first telescopic arm (71), first motor (72), sub- connector (73), female connector (74), rotating bar (75), Bristle (76), stirring sheet (77), rotary table (78) and the second motor (79), first telescopic arm (71) and second motor (79) it is fixed in side by side in the L shape supporting table, the fixed rotary table (78) of the output shaft of second motor (79), the circle The first plug (781) are arranged along edge in the bottom surface of platform (78), connect through first plug (781) and the rotary table (78) rotation Multiple rotating bars (75) are connect, the bristle (76), the other half described rotation is arranged in the bottom of rotating bar (75) described in half The bottom of bar (75) is arranged the stirring sheet (77), the fixed female connector (74) in the top of the rotating bar (75), and described the The fixed first motor (72) in the bottom of one telescopic arm (71), the fixed sub- connector of the output shaft of the first motor (72) (73), sub- connector (73) movement is plugged in the female connector (74).

4. drug resistant mutant genes of mycobacterium tuberculosis extraction element according to claim 1, which is characterized in that the extraction Mechanism (8) include the second telescopic arm (81), pumping cylinder (82), push rod (83), piston (84), swivel becket (85), pipette (86), Driving wheel (87), third motor (88) and L shape connecting rod (89), second telescopic arm (81) and the L shape connecting rod (89) the L shape supporting table, the fixed push rod (83) in the bottom of second telescopic arm (81), the push rod are fixed in side by side (83) the fixed piston (84) in bottom, the piston (84) are slidably connected to the pumping cylinder (82), the pumping cylinder (82) bottom is connected to the pipette (86), has external screw thread (861) on the outside of the pipette (86), the L shape connecting rod (89) top of cross bar one end is rotatablely connected the swivel becket (85), bottom setting the second plug (891), passes through the cross bar Snorkel (892) are set with second plug (891), internal screw thread, the pipette is arranged in the inner wall of the swivel becket (85) The cross bar and second plug (891) are sequentially passed through across the swivel becket (85), and the external screw thread (861) is bolted in The internal screw thread, the outside of the swivel becket (85) contradict the driving wheel (87), and the driving wheel (87) is fixed on described the Three motors (88), the third motor (88) are fixed on the vertical bar of the L shape connecting rod (89).

5. drug resistant mutant genes of mycobacterium tuberculosis extraction element according to claim 2, which is characterized in that the centrifugation Machine (4) includes the 4th motor (41), fixed station (42), fixed plate (43) and shell, and the shell is placed in the shielded box (1) bottom surface fixes the 4th motor (41), the fixed fixation of the output shaft of the 4th motor (41) in the shell Jack (431) are arranged on the fixed plate (43) in platform (42), hinged multiple fixed plates (43) on the fixed station (42), The centrifuge tube (92) is plugged in the jack (431), and the circular protrusion is connected on the jack (431).

6. drug resistant mutant genes of mycobacterium tuberculosis extraction element according to claim 2, which is characterized in that the machinery Arm (3) includes sliding block (31), three connecting rods (32), two joints (33) and work hand (34), three connecting rods (32) Between connected by the joint (33), and be rotatablely connected between the joint (33) and the connecting rod (32), positioned at both ends The sliding block (31) and the work hand (34) is respectively set in the connecting rod (32), and the sliding block (31) is slidably connected to the cunning Rail (2), the sliding block (31) side opposite with the sliding rail (2) are rotatablely connected electric roller (311), the work hand (34) The clamping container (9).

7. drug resistant mutant genes of mycobacterium tuberculosis extraction element according to claim 6, which is characterized in that the work Hand (34) includes the fixing seat in truncated rectangular pyramids shape, and clamping jaw (342) are arranged in the end of the fixing seat, and the clamping jaw (342) includes Two arc clips being oppositely arranged, one of them described arc clip are fixed on the fixing seat, another described arc folder Hingedly the fixing seat, the middle part of the fixing seat are rotatablely connected L-shaped movable claw (341) piece, and the movable claw (341) is living It is dynamic to be connected in semicircle groove.

8. drug resistant mutant genes of mycobacterium tuberculosis extraction element according to claim 6, which is characterized in that the joint It (33) include that the first link block (331), drive shaft (332) and the second link block (333), first link block (331) pass through Hinged second link block (333) of the drive shaft (332).