CN209471633U - A kind of external Bionic digestion system of dynamic people stomach-duodenum - Google Patents
A kind of external Bionic digestion system of dynamic people stomach-duodenum Download PDFInfo
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- CN209471633U CN209471633U CN201820889539.0U CN201820889539U CN209471633U CN 209471633 U CN209471633 U CN 209471633U CN 201820889539 U CN201820889539 U CN 201820889539U CN 209471633 U CN209471633 U CN 209471633U
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Abstract
The utility model discloses a kind of external Bionic digestion systems of dynamic people stomach-duodenum, oesophagus model, stomach model, duodenum model, wriggling pressurizing unit and digesting and emptying unit, oesophagus model, stomach model and duodenum model including heater incubator and in heater incubator are connected to each other;Wriggling pressurizing unit is respectively arranged at the two sides of oesophagus model, stomach model and duodenum model, for realizing the bionic movement of oesophagus model, stomach model and duodenum model;Digesting and emptying unit includes the feeding device being connected with oesophagus Model Inlet, the emptier for adding digestion liquid device and be connected with the outlet end of duodenum model being connected with stomach model and duodenum model.The utility model can real simulation human stomach, duodenal digestion process, provide accurate test data for research digestion, while to a certain extent can reduction zoopery and human experimentation appropriate.
Description
Technical field
The utility model belongs to external digestion emulation field, specifically, the utility model relates to a kind of dynamic people stomaches-ten
The external Bionic digestion system of two duodenum 12 can be used for food and medicine for that can simulate human stomach-duodenum digestion process equipment
The External digestion experiment of object.
Background technique
Up to now, most domestic and international in vitro digestions and absorption equipment to the anatomy of human body do not play it is bionical,
True effect, commonly simulates digestion reaction system for stirred reactor (glassware).Such as Chinese patent literature CN
103740589 disclose human gastrointestinal tract bionic system and the analogue experiment method based on the system, and this system has ignored very
The stirring theory of Flexible reactor and its interaction between food in real digestion process.
Utility model content
Therefore, the technical issues of the utility model is solved is: real simulation human stomach-duodenal digestion and row
Null process provides accurate data for test, and therefore, it is bionical in vitro that the utility model provides a kind of dynamic people stomach-duodenum
Digestive system.
The utility model provides a kind of external Bionic digestion system of dynamic people stomach-duodenum, the digestive system packet
Include heater incubator and oesophagus model, stomach model, duodenum model, wriggling pressurizing unit in the heater incubator
And digesting and emptying unit, the oesophagus model, stomach model and duodenum model are connected to each other;The wriggling pressurizing unit point
The two sides of the oesophagus model, stomach model and duodenum model are not set to, for realizing oesophagus model, stomach model and 12
The bionic movement of duodenum 12 model;The digesting and emptying unit includes the feeding device being connected with oesophagus Model Inlet and institute
What the stomach model and duodenum model stated were connected adds digestion liquid device and is connected with the outlet end of the duodenum model
The emptier connect;
Food is entered in the oesophagus model by the feeding device, and food is under the action of the wriggling pressurizing unit
It sequentially enters in stomach model and duodenum model, the digestive juice in described plus digestion liquid device enters the stomach model and 12
It in duodenum 12 model, and is mixed with food, food is discharged after completing digestion by the emptier.
Oesophagus model, stomach model and the duodenum model is silica gel model, is detachably fixed connection to each other,
The ratio of itself and true people's esophagus, stomach and duodenum is 1:1.
It is respectively equipped with a temperature element and PH acquisition elements on the oesophagus model, stomach model and duodenum model,
The temperature element is distributed at the oesophagus module inlet, the import of the entrance of stomach model and the duodenum model
Place;The PH acquisition elements are set at the pylorus below the stomach model and the exit of the duodenum model;It is described
Temperature element and PH acquisition elements and computer realize data connection.
Two sides is equipped with multiple gastric juice imports before and after the stomach model, and the front of the duodenum model is equipped with one
Bile import and a pancreatic juice import, it is described plus digestion liquid device respectively with the gastric juice import, bile import and pancreatic juice into
Mouth is connected, and is respectively used to inject gastric juice, bile and pancreatic juice into the stomach model, duodenum model.
The wriggling pressurizing unit includes for producing the oesophagus model, stomach model and duodenum model respectively
The vermiculator of raw biomimetic peristaltic comprising positioned at oesophagus model two sides and the multiple groups oesophagus bias convex surface wheel that is meshed and
It takes turns, positioned at the multiple groups stomach bias concave surface wheel and stomach off center plan wheel of the stomach model two sides and positioned at institute the fixed concave surface of oesophagus
State the multiple groups duodenum bias concave surface wheel and the fixed convex surface wheel of duodenum of duodenum model two sides;The eccentric convex surface
Wheel, eccentric concave surface wheel and off center plan wheel are driven by driving motor rotate respectively.
The wriggling pressurizing unit further includes that the direction of extrusion and the creeping effect power direction of the vermiculator are perpendicular
Stomach pressurizing unit is set to the two sides of the stomach model, comprising: pressure-ram squeezes motherboard and multiple groups extrusion head;It is described
Pressure-ram is fixedly connected with the extruding motherboard, for driving the extruding motherboard reciprocating, extrusion head described in multiple groups
It is vertically installed on the extruding motherboard, is threadedly coupled with extruding motherboard formation.
Pylorus clam identical with the stomach pressurizing unit active force is additionally provided at the pylorus below the stomach model,
The pylorus clam includes: to squeeze foreboard, squeeze back plate and pylorus push rod;The pylorus push rod and the fixed company of the extruding foreboard
It connects, for driving the extruding foreboard reciprocating;Trapezoidal outer male structure is formed in the extruding back plate;Before the extruding
Trapezoidal concave inward structure is formed on plate;The extruding foreboard and extruding back plate forms at a fully engaged.
The heater incubator includes cabinet, the heating lamp and temperature control device for being set to the box house;Described
For giving bionical organ to provide temperature, the heating lamp and the temperature control device are electrically connected heating lamp, for controlling described add
The heating temperature of thermolamp.
The adjustment device for adjusting the heater incubator placement angle is additionally provided in the digestive system comprising
Driving motor and attachment device;The driving motor is connected by the attachment device with the heater incubator;By described
The left-right rotation of driving motor realizes the angular adjustment to the heater incubator.
The feeding device includes Hopper support seat and funnel, and the Hopper support seat is set to the heater incubator
External top, the inlet communication of the lower end of the funnel and the oesophagus model.
For described plus digestion liquid device at least provided with three groups, described plus digestion liquid device includes liquid bath, digestive juice peristaltic pump
And inlet tube, inlet and each liquid bath of each digestive juice peristaltic pump are correspondingly connected with, each digestive juice peristaltic pump
One end of liquid outlet and each inlet tube is correspondingly connected with, the other end of each inlet tube respectively with the corresponding stomach model
It is connected with bile import, the pancreatic juice import on duodenum model with multiple gastric juice imports.
The emptier include empty peristaltic pump and with the evacuated tube that connect of emptying peristaltic pump, the evacuated tube and
The outlet end of the duodenum model connects.
Technical solutions of the utility model have the advantages that
A. the external Bionic digestion system of dynamic people stomach-duodenum disclosed by the utility model includes people's oesophagus model, stomach
Model, duodenum model, wriggling pressurizing unit, heater incubator and digesting and emptying unit, and consume emptying unit include into
Material device plus digestion liquid device and the emptier for being set to duodenum mold exit position;The utility model passes through oesophagus
Model, stomach model and duodenum model simulate the food digestion process of true man, compared at present using jar agitation dissolution and
Flushing etc. appropriate can be reduced dynamic to a certain extent come the method for studying food, drug digestion process, more science
Object experiment and human experimentation.
B. oesophagus model, stomach model and people's duodenum model are pressed the size of 1:1 to true people's stomach, ten by the utility model
Two duodenum 12 models carry out overmolded and make to obtain, and size, shape and internal physiological structures are consistent with true people's Stomach duodenum,
It is soft and have high resiliency and it is securely resistance to tear, wriggling pressurizing unit can simulate wriggling and the deformation of human digestive organ;Add
Hot incubator feeding tube, stomach and duodenum heating, by adding digesting and emptying unit into digestive system plus food and digestive juice,
Emptier is used to the food discharge after assist digestion, can full-scope simulation true man's digestion process, test data is reliable.
Detailed description of the invention
It, below will be right in order to illustrate more clearly of specific embodiment of the present invention or technical solution in the prior art
Specific embodiment or attached drawing needed to be used in the description of the prior art are briefly described, it should be apparent that, it is described below
In attached drawing be that some embodiments of the utility model are not paying creativeness for those of ordinary skill in the art
Under the premise of labour, it is also possible to obtain other drawings based on these drawings.
Fig. 1 is the people's esophageal-gastric-duodenum silica gel model schematic diagram of the utility model;
Fig. 2 is the wriggling, extruding and heating and heat-insulating device schematic diagram of the utility model;
Fig. 3 a is the main view that oesophagus bias convex surface is taken turns in Fig. 2;
Fig. 3 b is the right view that oesophagus bias convex surface is taken turns in Fig. 3 a;
Fig. 4 a is the main view of the fixed concave surface wheel of oesophagus in Fig. 2;
Fig. 4 b is the right view of the fixed concave surface wheel of oesophagus in Fig. 4 a;
Fig. 5 a is the main view of stomach in Fig. 2, duodenum bias concave surface wheel;
Fig. 5 b is the right view of stomach in Fig. 5 a, duodenum bias concave surface wheel;
Fig. 6 a is the main view of stomach off center plan wheel in Fig. 2;
Fig. 6 b is the right view of stomach off center plan wheel in Fig. 6 a;
Fig. 7 a is the main view of the fixed convex surface wheel of duodenum in Fig. 2;
Fig. 7 b is the right view of the fixed convex surface wheel of duodenum in Fig. 7 a
Fig. 8 a is the stomach pressurizing unit structural front view in Fig. 2;
Fig. 8 b is the side structure schematic diagram of Fig. 8 a;
Fig. 8 c is the overlooking structure diagram of Fig. 8 a;
Fig. 9 is pylorus clam detailed schematic in Fig. 2;
Figure 10 is the digestive system placement angle adjustment schematic device of the utility model;
Figure 11 is the charging of the utility model, auxiliary emptying and adds digestive juice schematic device.
In figure:
A- oesophagus model;B- stomach model;C- duodenum model;
1,2,3- temperature element;
4- gastric juice import;5- bile import;6- pancreatic juice import;
7,8,9-Ph acquisition elements;
10- heating lamp, 101- incubator lower layer heating lamp, 102- incubator lower layer heating lamp;11- cabinet;12- heating
Incubator;The oesophagus bias convex surface 13- wheel;The fixed concave surface wheel of 14- oesophagus;The stomach bias concave surface 15- wheel;16- stomach off center plan
Wheel;The duodenum bias concave surface 17- wheel;The fixed convex surface wheel of 18- duodenum;19- stomach pressurizing unit;20- pylorus clam;21-
Hopper support seat;22- peptic digest liquid peristaltic pump;23- gastric juice slot;24- gastric juice inlet tube;25- pancreas digestive juice peristaltic pump;26- pancreas
Liquid bath;27- pancreatic juice inlet tube;28- biliary digestion liquid peristaltic pump;29- bile slot;30- bile inlet tube;31- emptying is wriggled
Pump;32- evacuated tube;33- synchronizing shaft I;34- eccentric shaft I;35- bearing I;36- cam I;37- fixing axle I;38- concentric shafts I;
39- concave wheel I;40- synchronizing shaft II;41- eccentric shaft II;42- bearing I I;43- concave wheel II;44- synchronizing shaft III;45- eccentric shaft
III;46- bearing I II;47- fixing axle II;48- concentric shafts II;49- cam II;50- transition plates;51- extrusion head installation position
(not installing);52- extrusion head installation position (installation);53- squeezes motherboard;54- pressure-ram;55- extrusion head;After 56- is squeezed
Plate, the trapezoidal outer male structure of 561-;57- squeezes foreboard, the trapezoidal concave inward structure of 571-;58- pylorus push rod;59- driving motor;60-
Attachment device;61- funnel.
Specific embodiment
The technical solution of the utility model is clearly and completely described below in conjunction with attached drawing, it is clear that described
Embodiment is the utility model a part of the embodiment, instead of all the embodiments.Based on the embodiments of the present invention, originally
Field those of ordinary skill every other embodiment obtained without making creative work belongs to practical
Novel protected range.
As shown in Fig. 2, the utility model provides a kind of external Bionic digestion system of dynamic people stomach-duodenum, digestion
System includes heater incubator 12 and oesophagus model a in heater incubator 12, stomach model b, duodenum model c, compacted
Dynamic pressurizing unit and digesting and emptying unit, oesophagus model a, stomach model b and duodenum model c are connected to each other;It wriggles and squeezes dress
The two sides for being respectively arranged at oesophagus model a, stomach model b and duodenum model c are set, for realizing oesophagus model a, stomach model b
With the bionic movement of duodenum model c;Digesting and emptying unit include the feeding device being connected with oesophagus model a import, with
Stomach model b and duodenum model c is connected plus digestion liquid device and the row being connected with the outlet end of duodenum model c
Empty device.Wherein oesophagus model a, stomach model b and duodenum model c are both preferably silica gel model, are detachably fixed to each other
Connection.Certain each model can also be made of the material of other flexibilities.
Certainly, the utility model increases adjustment device, as shown in Figure 10, the tune of digestive system placement angle also in system
Engagement positions are made of driving motor 59 and attachment device 60;Attachment device 60 is by the case of driving motor 59 axis and heater incubator 12
Body is connected;Heater incubator 12 is transferred to by attachment device 60 when driving motor 59 rotates, realizes heater incubator 12
Rotation;
People's oesophagus model a- stomach model b- duodenum model c as shown in Figure 1 by 1:1 size to true people's oesophagus,
Stomach duodenum carries out overmolded and makes to obtain, oesophagus, the stomach, 12 of size, shape and internal physiological structures and true people
Duodenum 12 is consistent, soft and have high resiliency and securely resistance to tear.
Oesophagus model a in the utility model is connect with stomach model b with duodenum model c using dismountable mode;
As shown in Figure 1, having 3 temperature measuring points on people's oesophagus model a- stomach model b- duodenum model c, in this 3 temperature measuring point positions
Temperature element 1,2,3 is installed, the temperature element 1 of oesophagus model a entrance, the temperature element 2 of stomach model b entrance are distributed in
With the temperature element 3 of duodenum model c entrance.Temperature measurement is using thermocouple wire (0.5mm line footpath) as thermometric member
Part, and on computers by the real-time acquisition and recording of temperature data;On people's oesophagus model a- stomach model b- duodenum model c also
3 pH measurement points install PH acquisition elements in the position of this 3 side pH values respectively, and the PH for being specifically distributed in the front end stomach model a is adopted
Collect element 7, the PH acquisition elements 8 of pylorus rear end and the PH acquisition elements 9 in the exit duodenum model c.PH measurement is using small
Type pH meter records pH real time data acquisition on computers;Two sides is equipped with multiple gastric juice imports also before and after stomach model a simultaneously
4, guarantee that gastric juice is uniformly distributed in stomach;A bile import 5 and a pancreatic juice import are equipped in the front end of duodenum model c
6, bile and pancreatic juice are injected into duodenum model c respectively.
It introduces separately below and squeezes the pass wriggled for realizing oesophagus model a, stomach model b and duodenum model c
Key member.
As shown in Fig. 2, wriggling pressurizing unit is for realizing that oesophagus model a, stomach model b and duodenum model c are bionical
The vermiculator of movement;The wriggling of oesophagus model a is made jointly by oesophagus bias convex surface wheel 13 and the fixed concave surface wheel 14 of oesophagus
With realization;The wriggling of stomach is realized by stomach bias concave surface wheel 15 and 16 collective effect of stomach off center plan wheel;12
The wriggling of duodenum 12 model c is to take turns 18 collective effects by duodenum bias concave surface wheel 17 and the fixed convex surface of duodenum and realize
's;The opening and closing of pylorus is realized by pylorus clam 20.
As shown in Fig. 2, the utility model additionally provides the stomach pressurizing unit 19 for the existing front and back compressional movement of stomach excess, squeeze
It presses the creeping effect power direction of direction and vermiculator perpendicular, is set to the two sides of stomach model b, it is specific such as Fig. 8 a, 8b, 8c
It is shown, comprising: pressure-ram 54 squeezes motherboard 53 and multiple groups extrusion head 55;Pressure-ram 54 is by transition plates 50 and squeezes female
Plate 53 is fixedly connected, and for driving extruding motherboard 53 reciprocating, multiple groups extrusion head 55, which is vertically installed in, squeezes motherboard 53
On, it is threadedly coupled with the formation of motherboard 53 is squeezed.It is stretched by pressure-ram 54 to drive extruding motherboard 53 to be moved forward and backward,
The stretching frequency of pressure-ram 54, speed and stroke are adjustable;It squeezes on motherboard 53 by many extruding of the distribution of shapes of stomach model b
Head installation position 51,52, extrusion head installation position 51,52 are threaded hole;55 one end of extrusion head is semicircular structure for squeezing stomach mould
Type b, the other end are the distance before and after screw thread column structure can adjust on extrusion head installation position 51,52.The number of extrusion head 55
It can be adjusted according to position, the experiment condition etc. of gastric juice import 4 with position.
As shown in Figure 2 and Figure 9, it is additionally provided with and 19 active force of stomach pressurizing unit at the pylorus being located at below stomach model b
Identical 20 pylorus clam 20 of pylorus clam is made of extruding foreboard 57, extruding back plate 56 and pylorus push rod 58;Pylorus push rod 58 is flexible
It squeezes foreboard 57 to drive and is moved forward and backward, the stretching frequency of pylorus push rod 58, speed and stroke are adjustable;Squeezing foreboard 57 is
Trapezoidal outer male structure 571;Extruding back plate 56 is trapezoidal concave inward structure 561;Squeezing foreboard 57 and squeeze back plate 56 can be at a fully engaged.
As shown in Fig. 2, heater incubator 12 includes cabinet 11, the heating lamp 10 being set to inside cabinet 11 and temperature control dress
It sets;Heating lamp 10 therein includes incubator upper layer heating lamp 101 and incubator lower layer heating lamp 102, is respectively intended to bionical
Organ provides temperature, and heating lamp 10 is controlled by temperature control device;Cabinet 11 is organic glass structure, under the premise of guaranteeing visually
With certain heat insulation effect;Before heater incubator 12, it is left and right have door that can open, facilitate operation.
As shown in Fig. 2 and Fig. 3 a and Fig. 3 b, oesophagus bias convex surface wheel 13 is by synchronizing shaft I33, eccentric shaft I34,35 and of bearing I
Cam I36 is constituted;Synchronizing shaft I33 is connected with drive motor shaft by synchronous belt;Eccentric shaft I34 makes cam I36 do eccentric fortune
It is dynamic;Bearing I 35 is fastened on the outside of eccentric shaft I34 and on the inside of cam I36, guarantees to be roller when cam I36 and oesophagus model a is contacted
Friction rather than sliding friction, will not will be pulled under oesophagus model a;It can prevent from cutting using nylon material surface is smooth on the outside of cam I36
Get ill from overeating tube model a;The arc concave shape engagement of the fixed concave surface wheel 14 of the arc evagination and oesophagus of cam I36.
The fixed concave surface of oesophagus therein takes turns 14 as shown in figures 4 a and 4b, by fixing axle I37, concentric shafts I38 and concave wheel
I39 is constituted;Fixing axle I37 is fixed on the supporting plate;The external concave wheel I39 of fixing axle I37 is inscribed in concentric shafts I38;Concave wheel I39's adopts
Incised wound oesophagus model a can be prevented with nylon material surface is smooth;Oesophagus can be held well and be prevented by the concave structure of concave wheel I39
Oesophagus a is skidded off when being extruded;The arc evagination engagement of the arc concave shape of concave wheel I39 and oesophagus bias convex surface wheel wheel 13.
As shown in Fig. 2 and Fig. 5 a and Fig. 5 b, stomach bias concave surface wheel 15 and duodenum bias concave surface wheel 17 are by synchronizing shaft
II40, eccentric shaft II41, bearing I I42 and concave wheel II43 are constituted;Synchronizing shaft II40 is connected with drive motor shaft by synchronous belt;
Eccentric shaft II41 makes concave wheel II43 do eccentric motion;Bearing I I42 is fastened on the outside of eccentric shaft II41 and on the inside of concave wheel II43,
Guarantee to be roll friction when concave wheel II43 and stomach model b, duodenum model c are contacted rather than sliding friction, it will not be by stomach model
B, it is pulled under duodenum model c, concave wheel II43 can prevent incised wound stomach model b, duodenum mould using nylon material surface is smooth
Type c;The concave structure of concave wheel II43, which can well hold stomach model b, duodenum model c, to be prevented from sliding when being extruded
Out, and the arc evagination of the arc concave shape of concave wheel II43 and the fixed convex surface wheel 18 of duodenum engages.
As shown in Fig. 2 and Fig. 7 a and Fig. 7 b, stomach off center plan wheel 16 includes synchronizing shaft III44, eccentric shaft III45, axis
Hold III46 composition;Synchronizing shaft III44 is connected with drive motor shaft by synchronous belt;Eccentric shaft III45 is bearing I II46
Eccentric motion;Bearing I II46, which is fastened on the outside of eccentric shaft III45, to be guaranteed when bearing I II46 foreign steamer and stomach model b contact as rolling
Cylinder rubs rather than sliding friction, will not will pull under stomach model a.
As shown in Fig. 2 and Fig. 6 a and Fig. 6 b, the fixed convex surface wheel 18 of duodenum therein is by fixing axle II47, concentric shafts
II48 and cam II49 is constituted;Fixing axle II47 is fixed on the supporting plate, and the external cam of fixing axle II47 is inscribed in concentric shafts II48
II49;Cam II49 can prevent incised wound duodenum model c using nylon material surface is smooth;
As shown in figure 11, feeding device includes Hopper support seat 21 and funnel 61, and Hopper support seat 21 is set to heating and protects
The external top of incubator 12, the lower end of funnel 61 and the inlet communication of oesophagus model a, can be to oesophagus model a by funnel 61
Middle injection food.Add digestion liquid device at least provided with three groups, adding digestion liquid device includes liquid bath 23,26,29, digestive juice peristaltic pump
22,25,28 and inlet tube 24,27,30, liquid bath is respectively gastric juice slot 23, pancreatic juice slot 26 and bile slot 29, digestive juice peristaltic pump point
Not Wei peptic digest liquid peristaltic pump 22, pancreas digestive juice peristaltic pump 25 and biliary digestion liquid peristaltic pump 28, inlet tube be respectively gastric juice into
Liquid pipe 24, pancreatic juice inlet tube 27 and bile inlet tube 30, the inlet of each digestive juice peristaltic pump 22,25,28 and corresponding liquid bath
23,26,29 connection, the liquid outlet of each digestive juice peristaltic pump 22,25,28 are connected with one end of corresponding inlet tube 24,27,30,
The other end of each inlet tube 24,27,30 respectively with the bile import 5 on corresponding stomach model b and duodenum model c, pancreatic juice
Import 6 is connected with multiple gastric juice imports 4.And emptier includes the row for emptying peristaltic pump 31 and connecting with emptying peristaltic pump 31
Blank pipe 32, evacuated tube 32 are connect with the outlet end of duodenum model c.Peristaltic pump has 4, be respectively used to plus gastric juice, bile,
Pancreatic juice and for supplementary food empty;Liquid bath 23,26,29 has 3 to be respectively used to contain gastric juice, pancreatic juice and bile;Inlet tube
24,27,30,32 have four groups, are respectively used to add gastric juice, pancreatic juice, bile and emptying food;Gastric juice pipe 24 is divided into more by a supervisor
One end of a branch pipe, each branch pipe is connected with supervisor, and the other end is connected with the gastric juice import 4 on stomach wall.
The bilevel temperature of heater incubator is set on operation panel;Adjust oesophagus model, stomach model and 12
The relative angle of each eccentric wheel above duodenum 12 model;The speed of each runner is set on operation panel, setting stomach squeezes
Extruding frequency, speed and the depth of device set the opening and closing frequency and speed of pylorus;Food is added into funnel, opens and wriggles
Pump filling gastric juice, bile and pancreatic juice.Food enters oesophagus by funnel, wriggles on oesophagus by idler wheel and heating lamp is to temperature
Enter stomach after adjusting;Food is sufficiently mixed after being squeezed by the wriggling of stomach with gastric juice, while in the effect wriggled and squeezed
Lower physical size becomes smaller;Small size food after being broken enters duodenum by the narrow slit of pylorus;The food of small size is logical
It crosses after duodenal wriggling squeezes and is sufficiently mixed with bile and pancreatic juice, size further reduces to a certain extent;Food
It is discharged under the action of auxiliary empties peristaltic pump from duodenum end.
Technological means disclosed in the utility model is not limited to the technical means disclosed in the above technical means, also
Including technical solution consisting of any combination of the above technical features.
Obviously, the above embodiments are merely examples for clarifying the description, and does not limit the embodiments.It is right
For those of ordinary skill in the art, can also make on the basis of the above description it is other it is various forms of variation or
It changes.There is no necessity and possibility to exhaust all the enbodiments.And it is extended from this it is obvious variation or
It changes among the protection scope created still in the utility model.
Claims (10)
1. a kind of external Bionic digestion system of dynamic people stomach-duodenum, which is characterized in that the digestive system includes that heating is protected
It is incubator (12) and the oesophagus model (a) being located in the heater incubator (12), stomach model (b), duodenum model (c), compacted
Dynamic pressurizing unit and digesting and emptying unit, the oesophagus model (a), stomach model (b) and duodenum model (c) connect each other
It connects;The wriggling pressurizing unit is respectively arranged at the two of the oesophagus model (a), stomach model (b) and duodenum model (c)
Side, for realizing oesophagus model (a), stomach model (b) and the bionic movement of duodenum model (c);The digesting and emptying list
Member includes the feeding device being connected with oesophagus model (a) import and the stomach model (b) and duodenum model (c) phase
Emptier that is connection plus digesting liquid device and be connected with the outlet end of the duodenum model (c);
Food is entered in the oesophagus model by the feeding device, food under the action of the wriggling pressurizing unit successively
Into in stomach model and duodenum model, the digestive juice in described plus digestion liquid device enters the stomach model and duodenum
It in model, and is mixed with food, food is discharged after completing digestion by the emptier.
2. the external Bionic digestion system of dynamic people stomach-duodenum according to claim 1, which is characterized in that described
Oesophagus model (a), stomach model (b) and duodenum model (c) they are silica gel model, are detachably fixed connection to each other, with
The ratio of true people's esophagus, stomach and duodenum is 1:1.
3. the external Bionic digestion system of dynamic people stomach-duodenum according to claim 1, which is characterized in that described
A temperature element (1,2,3) and PH acquisition elements are respectively equipped on oesophagus model (a), stomach model (b) and duodenum model (c)
(7,8,9), the temperature element (1,2,3) are distributed in oesophagus module (a) entrance, the entrance of stomach model (b) and institute
State the entrance of duodenum model (c);The PH acquisition elements (7,8,9) are set to the pylorus below the stomach model (b)
Place and the exit of the duodenum model (c);The temperature element (1,2,3) and PH acquisition elements (7,8,9) and calculating
Machine realizes data connection.
4. the external Bionic digestion system of dynamic people stomach-duodenum according to claim 1, which is characterized in that the stomach
The front and back two sides of model (b) is equipped with multiple gastric juice imports (4), and the front of the duodenum model (c) is equipped with a bile
Import (5) and a pancreatic juice import (6), it is described plus digestion liquid device respectively with the gastric juice import (4), bile import (5)
It is connected with pancreatic juice import (6), is respectively used to inject gastric juice, bile into the stomach model (b), duodenum model (c)
And pancreatic juice.
5. the external Bionic digestion system of dynamic people stomach-duodenum according to claim 1, which is characterized in that described compacted
Dynamic pressurizing unit includes bionical for generating the oesophagus model (a), stomach model (b) and duodenum model (c) respectively
The vermiculator of wriggling, the vermiculator include the multiple groups oesophagus bias for being located at oesophagus model (a) two sides and being meshed
Take turns (13) and the fixed concave surface wheel (14) of oesophagus, the multiple groups stomach bias concave surface wheel (15) for being located at stomach model (b) two sides in convex surface
(17) are taken turns with stomach off center plan wheel (16) and the multiple groups duodenum bias concave surface for being located at duodenum model (c) two sides
With the fixed convex surface wheel (18) of duodenum;Eccentric convex surface wheel, eccentric concave surface wheel and the off center plan wheel passes through driving respectively
Motor driven rotation.
6. the external Bionic digestion system of dynamic people stomach-duodenum according to claim 5, which is characterized in that described compacted
Dynamic pressurizing unit further includes the direction of extrusion stomach pressurizing unit perpendicular with the creeping effect power direction of the vermiculator
(19), the two sides of the stomach model (b) are set to, comprising: pressure-ram (54) squeezes motherboard (53) and multiple groups extrusion head
(55);The pressure-ram (54) is fixedly connected with the extruding motherboard (53), past for driving the extruding motherboard (53) to make
Multiple to move, extrusion head (55) described in multiple groups is vertically installed on the extruding motherboard (53), with extruding motherboard (53) shape
At threaded connection;
Pylorus identical with stomach pressurizing unit (19) active force is additionally provided at the pylorus below the stomach model (b)
It presss from both sides (20), the pylorus clam (20) includes: to squeeze foreboard (57), squeeze back plate (56) and pylorus push rod (58);The pylorus pushes away
Bar (58) is fixedly connected with the extruding foreboard (57), for driving the extruding foreboard (57) reciprocating;The extruding
Trapezoidal outer male structure (561) is formed in back plate (56);Trapezoidal concave inward structure (571) are formed on the extruding foreboard (57);
The extruding foreboard (57) and extruding back plate (56) forms at a fully engaged.
7. -6 any dynamic people stomach-external Bionic digestion system of duodenum according to claim 1, which is characterized in that
The heater incubator (12) includes cabinet (11), is set to the internal heating lamp (10) of the cabinet (11) and temperature control dress
It sets;The heating lamp (10) is used to provide temperature to bionical organ, and the heating lamp (10) electrically connects with the temperature control device
It connects, for controlling the heating temperature of the heating lamp (10).
8. the external Bionic digestion system of dynamic people stomach-duodenum according to claim 7, which is characterized in that described
The adjustment device for adjusting the heater incubator (12) placement angle is additionally provided in digestive system comprising driving motor
(59) and attachment device (60);The driving motor (59) is connected by the attachment device (60) with the heater incubator (12)
It connects;The angular adjustment to the heater incubator (12) is realized by the left-right rotation of the driving motor (59).
9. the external Bionic digestion system of dynamic people stomach-duodenum according to claim 8, which is characterized in that described
Feeding device includes Hopper support seat (21) and funnel (61), and the Hopper support seat (21) is set to the heater incubator
(12) external top, the lower end of the funnel (61) and the inlet communication of the oesophagus model (a).
10. the external Bionic digestion system of dynamic people stomach-duodenum according to claim 9, which is characterized in that described
Add digestion liquid device at least provided with three groups, it is described plus digestion liquid device include liquid bath (23,26,29), digestive juice peristaltic pump (22,
25,28) and inlet tube (24,27,30), the inlet of each digestive juice peristaltic pump (22,25,28) and each liquid bath (23,
26,29) it is correspondingly connected with, the liquid outlet of each digestive juice peristaltic pump (22,25,28) and corresponding each inlet tube (24,
27,30) one end connection, the other end of each inlet tube (24,27,30) respectively with the corresponding stomach model (b) and ten
Bile import (5), pancreatic juice import (6) on two duodenum 12 models (c) are connected with multiple gastric juice imports (4);The emptier
Including emptying peristaltic pump (31) and with the evacuated tube (32) that connect of emptying peristaltic pump (31), the evacuated tube (32) with it is described
The outlet end of duodenum model (c) connects.
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110580847A (en) * | 2018-06-08 | 2019-12-17 | 中粮营养健康研究院有限公司 | Dynamic human stomach-duodenum in-vitro bionic digestion system |
CN111323208A (en) * | 2020-03-03 | 2020-06-23 | 重庆医疗器械质量检验中心 | Gastroscope dynamic simulation detection system |
-
2018
- 2018-06-08 CN CN201820889539.0U patent/CN209471633U/en active Active
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110580847A (en) * | 2018-06-08 | 2019-12-17 | 中粮营养健康研究院有限公司 | Dynamic human stomach-duodenum in-vitro bionic digestion system |
CN111323208A (en) * | 2020-03-03 | 2020-06-23 | 重庆医疗器械质量检验中心 | Gastroscope dynamic simulation detection system |
CN111323208B (en) * | 2020-03-03 | 2022-03-01 | 重庆医疗器械质量检验中心 | Gastroscope dynamic simulation detection system |
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