CN209451169U - A kind of Drug controlled release device - Google Patents
A kind of Drug controlled release device Download PDFInfo
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- CN209451169U CN209451169U CN201721539420.2U CN201721539420U CN209451169U CN 209451169 U CN209451169 U CN 209451169U CN 201721539420 U CN201721539420 U CN 201721539420U CN 209451169 U CN209451169 U CN 209451169U
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- Prior art keywords
- drug
- unit
- control unit
- controlled release
- release device
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- 229940079593 drug Drugs 0.000 title claims abstract description 53
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- 238000012544 monitoring process Methods 0.000 claims abstract description 15
- 238000012545 processing Methods 0.000 claims description 15
- 238000004891 communication Methods 0.000 claims description 6
- 230000001737 promoting effect Effects 0.000 abstract description 2
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Abstract
The utility model provides a kind of Drug controlled release device, and including control unit, drug release unit and feedback unit for acquiring drug release acoustical signal, the drug release unit includes ultrasound emission energy converter；Drug controlled release device in the utility model, ultrasound emission component is fed back by monitoring intracorporal acoustical signal and being formed, and then adjust the emission parameter of ultrasound, real-time monitoring release amount of medicine, achieve the purpose that accurate quantification discharges drug, the utility model structure is simple, at low cost, suitable for promoting the use of a large area.
Description
Technical field
The utility model relates to medical device technical foundation research field more particularly to a kind of Drug controlled release devices.
Background technique
In recent years, high intensity focused ultrasound (High-intensity focused Ultrasound, abbreviation HIFU) conduct
It is a kind of to be developed rapidly without invasive treatment means, and, it is already possible to it uses experiments have shown that having reached clinic in some applications
Effect, such as: various pernicious benign tumours and such as brain, prostate, liver, mammary gland, kidney, glaucoma, ophthalmo melanoma,
Fibroma uteri, benign hypertrophy of the prostate and cardiovascular and cerebrovascular disease etc..
In the case that HIFU may not need operation, the ultrasonic wave emitted in vitro is penetrated into surface texture, focuses on internal target
Area generates the biological effects such as transient high temperature (60 DEG C or more), cavitation, mechanism, reaches the tumour cell killed in target area
Purpose.
Ultrasonic cavitation refers to that the micro-bubble being present in liquid (cavitation nucleus) is vibrated under the action of ultrasonic field, grown simultaneously
The process of collapse.The process can cause the rupture of medicine-carrying microvesicle, discharge drug.Because focusing the good penetrability of ultrasound, determining
Position property and energy deposition.It can be used as a kind of control means for discharging drug.
But currently available technology lacks the monitoring to acoustical signal in tissue, can not form feedback, cause drug in ultrasound
Burst size can not be adjusted according to ultrasonication situation in time after release, medicine can not be done to release drug and accurately quantitatively discharged.
Utility model content
In view of the foregoing deficiencies of prior art, the utility model provides a kind of Drug controlled release device, to solve
Above-mentioned technical problem.
Drug controlled release device provided by the utility model, including control unit, drug release unit and for acquiring
The feedback unit of drug release acoustical signal, the drug release unit include ultrasound emission energy converter；
The output end of described control unit is connect with the input terminal of drug release unit, the input terminal of described control unit with
The input terminal of feedback unit connects.
Further, the feedback unit is ultrasonic reception energy converter.
It further, further include signal processing unit, the input terminal of the signal processing unit and the output end of feedback unit
Connection, the output end of the signal processing unit and the input terminal of control unit connect, and the signal processing unit includes successively
Signal amplifier, filter and the analog-digital converter of connection.
Further, the ultrasound emission energy converter is arranged in the same direction with ultrasonic reception energy converter, the ultrasound emission energy converter
It is set to the front end of ultrasonic reception energy converter.
Further, described control unit includes controller and comparator, be preset in the comparator for acquisition
The threshold value that drug release acoustical signal is compared.
It further, further include monitoring server and communication unit, described control unit passes through communication unit and monitoring service
Device connection.
It further, further include mobile control unit, the mobile control unit and monitoring server are wirelessly connected, and are counted
According to exchange, the mobile control unit includes the group of one or more of smart phone, tablet computer or intelligent handheld device
It closes.
The utility model has the beneficial effects that the Drug controlled release device in the utility model, by monitoring intracorporal sound
Signal, which is formed, feeds back ultrasound emission component, and then adjusts the emission parameter of ultrasound, and real-time monitoring release amount of medicine reaches
Accurate quantification discharges the purpose of drug, and the utility model structure is simple, at low cost, suitable for promoting the use of a large area.
Detailed description of the invention
Fig. 1 is the schematic illustration of the Drug controlled release device in the utility model embodiment.
Fig. 2 is the structural schematic diagram of the Drug controlled release device in the utility model embodiment.
Description of symbols:
1- transmitting transducer, 2- receive energy converter, 3- in-vivo tissue, 4- drug release area.
Specific embodiment
Illustrate the embodiments of the present invention below by way of specific specific example, those skilled in the art can be by this theory
Content disclosed by bright book understands other advantages and effect of the utility model easily.The utility model can also be by addition
Different specific embodiments are embodied or practiced, and the various details in this specification can also be based on different viewpoints and answer
With carrying out various modifications or alterations under the spirit without departing from the utility model.It should be noted that the case where not conflicting
Under, the feature in following embodiment and embodiment can be combined with each other.
It should be noted that diagram provided in following embodiment only illustrates the basic of the utility model in a schematic way
Conception, only shown in schema then with related component in the utility model rather than component count when according to actual implementation, shape
And size is drawn, when actual implementation kenel, quantity and the ratio of each component can arbitrarily change for one kind, and its assembly layout
Kenel may also be increasingly complex.
As shown in Figure 1, the Drug controlled release device in the present embodiment, including control unit, drug release unit and use
In the feedback unit of acquisition drug release acoustical signal, the drug release unit includes ultrasound emission energy converter；
The output end of described control unit is connect with the input terminal of drug release unit, the input terminal of described control unit with
The input terminal of feedback unit connects.
In the present embodiment, drug release unit uses ultrasound emission energy converter, and feedback unit is ultrasonic reception energy converter,
Ultrasound emission energy converter is controlled by control unit, the accurate quantitative release to drug release is realized, in real work
In, starting transmitting transducer starts to discharge drug first, while receiving energy converter start-up operation, the acoustical signal in tissue is received,
Ultrasound emission component is fed back, control unit adjusts the emission parameter of ultrasound based on the feedback signal and then in real time, realizes
Real-time monitoring release amount of medicine.
As shown in Fig. 2, further including signal processing unit, the input terminal and feedback of signal processing unit in the present embodiment
The output end of unit connects, and the output end of the signal processing unit and the input terminal of control unit connect, the signal processing
Unit includes sequentially connected signal amplifier, filter and analog-digital converter, by signal amplifier to received acoustical signal
Processing is amplified, then in turn through filter and analog-digital converter is filtered to amplified acoustical signal and A/D
Control unit is sent to after conversion process to be compared.
In the present embodiment, control unit includes controller and comparator, be preset in the comparator for acquisition
The threshold value that is compared of drug release acoustical signal, acquisition signal is compared by comparator, then according to preset threshold
Value adjusts the emission parameter of ultrasound in real time, to achieve the purpose that automatic Drug controlled release accurate in real time.
In the present embodiment, ultrasound emission energy converter is arranged in the same direction with ultrasonic reception energy converter, the ultrasound emission transducing
Device is set to the front end of ultrasonic reception energy converter, it is preferable that two probes can also use integrated setting, by popping one's head in disease
The injection drug for becoming position is accurately controlled, drug can by oral, can also be injected by way of injection it is internal,
It, can be through this embodiment for some diseased regions or the organic region and angiosomes that need to carry out drug release control
In device carry out local excitation, and drug release is carried out automatically controlling according to feedback；It is highly preferred that drug release unit can be with
Including multiple groups ultrasound emission energy converter, feedback unit correspondingly also may include multiple groups ultrasonic reception energy converter engaged therewith,
Multiple groups ultrasound emission energy converter and ultrasonic reception energy converter are connect with control unit respectively, can uniformly be controlled, can also be with
It is independently controlled respectively for each ultrasonic reception energy converter and ultrasound emission energy converter.
In this embodiment, it is preferred that can also be described including monitoring server, communication unit and mobile control unit
Control unit is connect by communication unit with monitoring server, and mobile control unit and monitoring server are wirelessly connected, and is counted
According to exchange, the mobile control unit includes smart phone, tablet computer or the medium intelligent handheld device of intelligent handheld device, is led to
It crosses and corresponding APP is installed remotely to be monitored to drug release, when necessary, can also be carried out by mobile control unit long-range
Control.
In the present embodiment, general processor, including central processing unit be can be in control unit
(CentralProcessingUnit, abbreviation CPU), network processing unit (NetworkProcessor, abbreviation NP) etc.；It can be with
It is digital signal processor (DigitalSignalProcessing, abbreviation DSP), specific integrated circuit (ApplicationS
PecificIntegratedCircuit, abbreviation ASIC), field programmable gate array (Field-
ProgrammableGateArray, abbreviation FPGA) either other programmable logic device, discrete gate or transistor logic device
Part, discrete hardware components, it is preferable that the control unit in the present embodiment uses single-chip microcontroller, and those skilled in the art could be aware that,
There is the component that can be realized above-mentioned function can be substituted for other, then this is repeated no more.
The above embodiments are only illustrative of the principle and efficacy of the utility model, and not for limitation, this is practical new
Type.Any person skilled in the art can all carry out above-described embodiment under the spirit and scope without prejudice to the utility model
Modifications and changes.Therefore, such as those of ordinary skill in the art without departing from the revealed essence of the utility model
All equivalent modifications or change completed under mind and technical idea, should be covered by the claim of the utility model.
Claims (7)
1. a kind of Drug controlled release device, it is characterised in that: including control unit, drug release unit and for acquiring drug
The feedback unit of acoustical signal is discharged, the drug release unit includes ultrasound emission energy converter；
The output end of described control unit is connect with the input terminal of drug release unit, the input terminal and feedback of described control unit
The input terminal of unit connects.
2. Drug controlled release device according to claim 1, it is characterised in that: the feedback unit changes for ultrasonic reception
It can device.
3. Drug controlled release device according to claim 2, it is characterised in that: it further include signal processing unit, it is described
The input terminal of signal processing unit and the output end of feedback unit connect, the output end and control unit of the signal processing unit
Input terminal connection, the signal processing unit includes sequentially connected signal amplifier, filter and analog-digital converter.
4. Drug controlled release device according to claim 2, it is characterised in that: the ultrasound emission energy converter and ultrasound
It receives energy converter to be arranged in the same direction, the ultrasound emission energy converter is set to the front end of ultrasonic reception energy converter.
5. Drug controlled release device according to claim 1, it is characterised in that: described control unit include controller and
Comparator is preset with the threshold value being compared for the drug release acoustical signal with acquisition in the comparator.
6. Drug controlled release device according to claim 1, it is characterised in that: further include monitoring server and communication unit
Member, described control unit are connect by communication unit with monitoring server.
7. Drug controlled release device according to claim 6, it is characterised in that: it further include mobile control unit, it is described
Mobile control unit and monitoring server are wirelessly connected, and carry out data exchange, and the mobile control unit includes smart phone, puts down
The combination of one or more of plate computer or notebook.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201721539420.2U CN209451169U (en) | 2017-11-16 | 2017-11-16 | A kind of Drug controlled release device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201721539420.2U CN209451169U (en) | 2017-11-16 | 2017-11-16 | A kind of Drug controlled release device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN209451169U true CN209451169U (en) | 2019-10-01 |
Family
ID=68034805
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201721539420.2U Expired - Fee Related CN209451169U (en) | 2017-11-16 | 2017-11-16 | A kind of Drug controlled release device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN209451169U (en) |
-
2017
- 2017-11-16 CN CN201721539420.2U patent/CN209451169U/en not_active Expired - Fee Related
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| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20191001 |
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| CF01 | Termination of patent right due to non-payment of annual fee |