CN209437410U - A kind of tree shrew intestinal flora collection device - Google Patents

A kind of tree shrew intestinal flora collection device Download PDF

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Publication number
CN209437410U
CN209437410U CN201821101487.2U CN201821101487U CN209437410U CN 209437410 U CN209437410 U CN 209437410U CN 201821101487 U CN201821101487 U CN 201821101487U CN 209437410 U CN209437410 U CN 209437410U
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CN
China
Prior art keywords
tree shrew
flora collection
collection box
intestinal flora
pedestal
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Expired - Fee Related
Application number
CN201821101487.2U
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Chinese (zh)
Inventor
王利梅
李波
郑红
罗夙医
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Kunming Medical University
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Kunming Medical University
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Priority to CN201821101487.2U priority Critical patent/CN209437410U/en
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Expired - Fee Related legal-status Critical Current
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Abstract

The utility model provides a kind of tree shrew intestinal flora collection device, including the fixed device of tree shrew and flora collection box, the flora collection box is arranged in below the pedestal of the fixed device of tree shrew, pedestal is equipped with the track matched with above the flora collection box, drawer-type structure is constituted, pedestal is equipped with and the consistent through-hole of flora collection box opening.It is transferred in sampling pipe after first collecting sample using the sampling apparatus, there is filter membrane in sampling apparatus, urine can exclude, and reduce pollution of the urine to sample;Intestinal flora sample can be directly entered sampling pipe from outlet, shorten sample acquisition time, reduce microbial contamination of the environment to sample in sampling process.The problem of experimental animal can be fixed time saving and energy savingly simultaneously, experimental animal is reduced and struggle, get rid of more people operation, sampling efficiency is improved, prevent intestinal flora sample from polluting, be convenient for sample collection, device may be reused, and reduce sampling cost, easy to operate.

Description

A kind of tree shrew intestinal flora collection device
Technical field
The utility model relates to the collection technique fields of microbial population of animal intestinal tract, and in particular to a kind of tree shrew intestinal flora collection Device.
Background technique
Existing research shows that the multifarious reduction of intestinal flora is related to fat and other health problems, and enterobacteriaceae The multifarious increase of group is then conducive to metabolic and immune.Intestinal flora has important influence to human health, is reported There is close association in road and cardiovascular and cerebrovascular disease, obesity, diabetes, AIDS, self-closing disease, depression and senile dementia etc., because This, study on intestinal flora becomes research hotspot in recent years.Human body intestinal canal flora and various diseases close association, work as intestinal flora It will form intestinal bacilli illness when being broken with the dynamic balance state of human body and external environment, and then cause disease or add The original state of an illness of weight.
Experimental animal tree shrew physiology, biochemical indicator and its in terms of and the mankind it is closely similar, it is in addition more square Just the advantage raised, observe and operated, so tree shrew can be used as the dynamic of duplication human diseases in the research of intestinal flora Object model.Therefore in the research of intestinal flora, the collection of intestinal flora (also known as " fecal bacteria ", " caprophyl ") is just to Guan Chong It wants.
What the collection of experimental animal intestinal flora generallyd use at present is abdomen massage method or forces method and both sides The cooperation of method, by gently extrusion experiment animal abdomen or pressing animal tail end tip with cause the stress reaction of animal come Acquire the caprophyl of animal rectum end.But in operation, at least two people are needed to cooperate, a people embraces tree since tree shrew is vivaciously liked to move Shrew fixes its head and upper limb on the other hand, and the other hand fixes its lower limb;Other people abdomen massage squeezes animal tail end point End, and collect caprophyl.One man operation can not be completed substantially.
Still further aspect, currently, this method of sampling is usually to collect to enter by the dynamic caprophyl of experiment with sterilized cotton swabs to adopt Sample pipe.Intestinal flora sample quick freeze can be guaranteed into the integrality of flora cdna sample in this method short time, but deposited In following problems: on the one hand, experimental subjects meeting continuously active in sampling process needs special messenger to fix, and causes sampling inconvenient; On the other hand, continuously active is understood in sampling process due to experimental subjects and urinated, be easy to cause collected sample by urine The cross contaminations such as cross contamination or operator's gloves attachment.
Utility model content
The utility model is directed to missing of the existing technology, and main purpose is to provide one kind and is capable of fixing experiment tree shrew, And sample is prevented to be positively retained at the intestinal flora collection device of flora cdna sample integrality.
Technical solutions of the utility model are as follows:
A kind of tree shrew intestinal flora collection device, including tree shrew fixed device (1) and flora collection box (2), the tree Shrew fixed device (1) be provided with support plate (12), support support plate (12) vertical support rod (17a) and with vertical support rod The horizontal support bar (17b) of cooperation;It is provided with a sliding slot (13) in the support plate (12), setting is at the top of support plate (12) Head standoffs part (11), adjusted by the way that pulley is mobile on sliding slot (13), be symmetricly set on being used for for sliding slot (13) two sides It fixes tree shrew four limbs fixation member (14), pulley is provided in tree shrew four limbs fixation member (14) and sliding slot (13) cooperation is adjusted; Pedestal (15) below support plate is set by sliding slot (13);Flora collection box (2) setting is in the fixed device of tree shrew (1) below pedestal (15), pedestal (15) is equipped with and the consistent through-hole (15a) of the flora collection box (2) opening.
Further, animal wastes are taken out for convenience, clean collection box, are reused, the flora collection box (2) For drawer type, by can the portion of pumping take part (21) to form with flora collection box fixed frame (22), on flora collection box fixed frame (22) Equipped with through-hole corresponding with base plate through holes (15a), can extraction section be made of the box body that filter membrane (23) is divided into upper and lower two layers.
Further, the angle of the pedestal (15) and support plate (12) is not less than 90 degree.
Further, in order to facilitate the angle of adjustment base and support plate, the support plate (12) bottom is additionally provided with tune The adjustable plate (18) of pedestal and support plate angle is saved, the protrusion (19) of adjustable frames angle is provided on the pedestal.
In order to avoid animal comes to harm, the head standoffs part (11) is an arc groove, arc groove both ends Equipped with the buckle (11c) on head mount, buckle is equipped with bandage (11a) of the head mount with velcro.
Preferably, the arcuate recess surface is all attached with head protection elastic sponge or rubber (11b).
In order to avoid animal foot comes to harm, the four limbs phase with tree shrew is provided in the four limbs fixation member (14) The arc groove of adaptation, arc groove both ends are equipped with four limbs fixation member buckle (14c), and four limbs fixation member buckles on (14c) Equipped with the bandage (14a) in four limbs fixation member with velcro, arcuate recess surface is all attached with the bullet in four limbs fixation member Property sponge or rubber (14b).
Further, the shape of the flora collection box (2) is cuboid, square, cylindrical body or cone.
Working principle: in use, by the track below pedestal, lower section flora collection box is installed, further according to tree shrew Size by sliding slot adjust head fixing device, the position of limbs fixing device on the supporting plate, fix the head of tree shrew And four limbs, and make the tail portion of tree shrew just in the bottom side of taking, tree shrew abdomen is then massaged, its intestines peristalsis is stimulated, makes its defecation. Defecation is directly entered on the top filter membrane of the flora collection box of lower section by through-hole, if any urine, is then received by filter membrane to flora Collect the lower section of box.When collection finishes, drawer type flora collection box is directly taken out, is tested.
Intestinal flora collection device provided by the utility model, compared with the existing technology, have it is following the utility model has the advantages that
1) the utility model structure is simple, easy to operate, using the experimental animal of the device for fixing experimental animal It the problem of experimental animal can be fixed time saving and energy savingly, get rid of more people operation, can when facilitating experimenter to operate, while testing Animal is reduced to struggle, it is low in cost, have good market promotion prospect.
2) sampling efficiency can be improved, prevent intestinal flora sample from polluting, be convenient for sample collection.Drawer type flora collection box side Just hygienic, it is readily cleaned disinfection, is reused.It is transferred in sampling pipe after first collecting sample using the sampling apparatus, sampling cartridge There is filter membrane in setting, urine can exclude, and reduce pollution of the urine to sample;Intestinal flora sample can be directly entered from outlet Sampling pipe shortens sample acquisition time, reduces microbial contamination of the environment to sample in sampling process.Device can repeat to make With reduction sampling cost.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of intestinal flora collection device in the preferred embodiment in the utility model;
Fig. 2 is the utility model side view
Fig. 3 is the utility model top view
Fig. 4 is the utility model flora collection box schematic diagram
Appended drawing reference: the fixed device of 1- tree shrew, 2- flora collection box, 11- head standoffs part, on 11a- head mount Bandage with velcro, 11b- head protection elastic sponge or rubber, the buckle on 11c- head mount, 12- support plate, 13- sliding slot, 14- four limbs fixation member, the bandage with velcro in 14a- four limbs fixation member, in 14b- four limbs fixation member Elastic sponge or rubber, 14c- four limbs fixation member buckle, 15- pedestal, 15a- through-hole, the vertical support rod of 17a-, 17b- water Flat support rod, the adjustable plate of 18- support plate angle, the protrusion of 19- adjustment base angle, 21- can the portion of pumping take part, 22-floras Collection box fixed frame, 23- filter membrane
Specific embodiment
Below in conjunction with the attached drawing in the utility model embodiment, to the technical solution in the utility model embodiment It is clearly and completely described.
A kind of tree shrew intestinal flora collection device, including the fixed device 1 of tree shrew and flora collection box 2, the tree shrew are consolidated Determine device 1 to be provided with support plate 12, support the vertical support rod 17a of support plate 12 and prop up with the horizontal of vertical support rod cooperation Strut 17b;It is provided with a sliding slot 13 in the support plate 12, the head standoffs part 11 at 12 top of support plate is set, is led to Cross that pulley is mobile on sliding slot 13 to be adjusted, be symmetricly set on 13 two sides of sliding slot for fixing tree shrew four limbs fixation member 14, set It is provided with pulley in Shrew four limbs fixation member 14 and the cooperation of sliding slot 13 is adjusted;Pedestal below support plate is set by sliding slot 13 15;The flora collection box 2 is arranged in below the pedestal 15 of the fixed device 1 of tree shrew, and pedestal 15 is equipped with and the flora Collection box 2 is open consistent through-hole 15a.In order to facilitate animal wastes are taken out, collection box is cleaned, is reused, the flora Collection box 2 be drawer type, by can the portion of pumping take part 21 to form with flora collection box fixed frame 22, on flora collection box fixed frame 22 Equipped with through-hole corresponding with base plate through holes 15a, can extraction section be made of the box body that filter membrane 23 is divided into upper and lower two layers.It is described Pedestal 15 and support plate 12 angle be not less than 90 degree.In order to facilitate the angle of adjustment base and support plate, the support 12 bottom of plate is additionally provided with the adjustable plate 18 of adjustment base Yu support plate angle, is provided with adjustable frames angle on the pedestal Protrusion 19.In order to avoid animal comes to harm, the head standoffs part 11 is an arc groove, and arc groove both ends are set There are the buckle 11c on head mount, buckle 11c to be equipped with the bandage 11a with velcro on head mount.The arc Groove surfaces are all attached with head protection elastic sponge or rubber 11b.In order to avoid animal foot comes to harm, the four limbs Arc groove compatible with the four limbs of tree shrew is provided in fixation member 14, arc groove both ends are equipped with four limbs fixation member card 14c is detained, buckle 14c is equipped with the bandage 14a with velcro in four limbs fixation member, and it is solid that arcuate recess surface is all attached with four limbs Determine the elastic sponge or rubber 14b on component.The shape of the flora collection box 2 is cuboid, square, cylindrical body or circle Centrum.
In use, lower section flora collection box is installed, is passed through further according to the size of tree shrew by the track below pedestal Sliding slot adjusts head fixing device, the position of limbs fixing device on the supporting plate, fixes head and the four limbs of tree shrew, and make Tree shrew abdomen is then massaged, its intestines peristalsis is stimulated, makes its defecation just in the bottom side of taking in the tail portion of tree shrew.Defecation passes through logical Hole is directly entered on the top filter membrane of the flora collection box of lower section, if any urine, then passes through filter membrane to the lower section of flora collection box. When collection finishes, drawer type flora collection box is directly taken out, is tested.
Intestinal flora collection device provided by the utility model, compared with the existing technology, have it is following the utility model has the advantages that
1) the utility model structure is simple, easy to operate, using the experimental animal of the device for fixing experimental animal It the problem of experimental animal can be fixed time saving and energy savingly, get rid of more people operation, can when facilitating experimenter to operate, while testing Animal is reduced to struggle, it is low in cost, have good market promotion prospect.
2) sampling efficiency can be improved, prevent intestinal flora sample from polluting, be convenient for sample collection.Drawer type flora collection box side Just hygienic, it is readily cleaned disinfection, is reused.It is transferred in sampling pipe after first collecting sample using the sampling apparatus, sampling cartridge There is filter membrane in setting, urine can exclude, and reduce pollution of the urine to sample;Intestinal flora sample can be directly entered from outlet Sampling pipe shortens sample acquisition time, reduces microbial contamination of the environment to sample in sampling process.Device can repeat to make With reduction sampling cost.
The above is preferred embodiments of the present invention, and but it cannot be understood as special to the utility model The limitation of sharp range.It should be pointed out that for those skilled in the art, not departing from the utility model principle Under the premise of, several improvements and modifications can also be made, these improvements and modifications are also considered as the protection scope of the utility model.

Claims (8)

1. a kind of tree shrew intestinal flora collection device, it is characterised in that: device (1) and flora collection box (2) are fixed including tree shrew, The tree shrew fixed device (1) be provided with support plate (12), support support plate (12) vertical support rod (17a) and with it is perpendicular The horizontal support bar (17b) of support bars cooperation;It is provided with a sliding slot (13), is arranged in support plate in the support plate (12) (12) the head standoffs part (11) at the top of adjusts by the way that pulley is mobile on sliding slot (13), is symmetricly set on sliding slot (13) two Side is used to fix tree shrew four limbs fixation member (14), and pulley is provided in tree shrew four limbs fixation member (14) and is matched with sliding slot (13) It closes and adjusts;Pedestal (15) below support plate is set by sliding slot (13);Flora collection box (2) setting is solid in tree shrew Below the pedestal (15) for determining device (1), pedestal (15) is equipped with and the consistent through-hole of the flora collection box (2) opening (15a)。
2. tree shrew intestinal flora collection device according to claim 1, it is characterised in that: the flora collection box (2) For drawer type, by can the portion of pumping take part (21) to form with flora collection box fixed frame (22), on flora collection box fixed frame (22) Equipped with through-hole corresponding with base plate through holes (15a), and with can extraction section be divided by filter membrane (23) upper and lower two layers of box body structure At upper layer is open.
3. tree shrew intestinal flora collection device according to claim 1, it is characterised in that: the pedestal (15) and support The angle of plate (12) is not less than 90 degree.
4. tree shrew intestinal flora collection device according to claim 1, it is characterised in that: described support plate (12) bottom It is additionally provided with the adjustable plate (18) of adjustment base Yu support plate angle, the protrusion of adjustable frames angle is provided on the pedestal (19).
5. tree shrew intestinal flora collection device according to claim 1, it is characterised in that: the head standoffs part It (11) is an arc groove, arc groove both ends are equipped with the buckle (11c) on head mount, and buckle is equipped with head mount Bandage (11a) with velcro.
6. tree shrew intestinal flora collection device according to claim 5, it is characterised in that: the arcuate recess surface is all It is attached with head protection elastic sponge or rubber (11b).
7. tree shrew intestinal flora collection device according to claim 1, it is characterised in that: the four limbs fixation member (14) arc groove compatible with the four limbs of tree shrew is provided on, arc groove both ends are buckled equipped with four limbs fixation member (14c), four limbs fixation member buckle (14c) and are equipped with the bandage (14a) with velcro in four limbs fixation member, arc groove table Face is all attached with elastic sponge or rubber (14b) in four limbs fixation member.
8. tree shrew intestinal flora collection device according to claim 2, it is characterised in that: the flora collection box (2) Shape be cuboid, square, cylindrical body or cone.
CN201821101487.2U 2018-07-12 2018-07-12 A kind of tree shrew intestinal flora collection device Expired - Fee Related CN209437410U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201821101487.2U CN209437410U (en) 2018-07-12 2018-07-12 A kind of tree shrew intestinal flora collection device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201821101487.2U CN209437410U (en) 2018-07-12 2018-07-12 A kind of tree shrew intestinal flora collection device

Publications (1)

Publication Number Publication Date
CN209437410U true CN209437410U (en) 2019-09-27

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CN201821101487.2U Expired - Fee Related CN209437410U (en) 2018-07-12 2018-07-12 A kind of tree shrew intestinal flora collection device

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110946671A (en) * 2019-12-23 2020-04-03 天津市海河医院 Lying-down mouse fixing device
CN112190286A (en) * 2020-09-30 2021-01-08 四川大学华西医院 Intestinal flora collecting device
CN115227295A (en) * 2022-09-19 2022-10-25 深圳市雄帝科技股份有限公司 Pharynx swab sampling device

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110946671A (en) * 2019-12-23 2020-04-03 天津市海河医院 Lying-down mouse fixing device
CN112190286A (en) * 2020-09-30 2021-01-08 四川大学华西医院 Intestinal flora collecting device
CN112190286B (en) * 2020-09-30 2023-04-21 四川大学华西医院 Intestinal flora collecting device
CN115227295A (en) * 2022-09-19 2022-10-25 深圳市雄帝科技股份有限公司 Pharynx swab sampling device

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CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20190927

Termination date: 20200712