CN209310459U - A kind of multi-functional digestion instrument sampling probe cleaning-drying instrument - Google Patents
A kind of multi-functional digestion instrument sampling probe cleaning-drying instrument Download PDFInfo
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- CN209310459U CN209310459U CN201821491814.XU CN201821491814U CN209310459U CN 209310459 U CN209310459 U CN 209310459U CN 201821491814 U CN201821491814 U CN 201821491814U CN 209310459 U CN209310459 U CN 209310459U
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- sampling probe
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- purge tank
- sampling
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Abstract
The utility model relates to clean, dry the instrument of digestion instrument sampling probe, and in particular to a kind of multi-functional digestion instrument sampling probe cleaning-drying instrument, it is characterised in that it includes purge tank, sampling needle interface, air generation, heating device and waste liquid reception device, bracket；The purge tank is cylindrical, and the purge tank top nose is equipped with cleaning solution feed opening, and top rear is occurred by gas-guide tube with air, heating device is connected to；Purge tank side is equipped with cleaning solution form；It is equipped with a row at purge tank A line and samples needle interface, sampling probe is inserted into sampling needle interface.The utility model is easy to operate, quick.Scavenging period is set, all operationss can be completed in drying time, do not need Manual-cleaning, can greatly reduce the labor intensity of research staff.
Description
Technical field
The utility model provides the instrument of the novel conveniently and efficiently cleaning of one kind, dry digestion instrument sampling probe.
Background technique
After oral administration, drug can release oral drugs from preparation, new drug development or imitation medicine R&D process
The release conditions of drug in analogue body in vitro are needed, In Vitro Dissolution experiment is usually used in instructing the research and development of pharmaceutical preparation, evaluation system
In agent batch and batch between quality difference, evaluation Medicine prescription technique before changing after quality and curative effect consistency, used instrument
Device is called digestion instrument.Digestion instrument is a kind of instrument of drug release in analogue body, provides one kind by microcomputer for dissolution method
The electromechanical integration testing equipment of control, mainly by groups such as motor, thermostat, basket body, agitating paddle, stripping rotor and cup lids
At.
It is cleaned with syringe or is directly rinsed with tap when current each R&D institution's sampling probe cleaning, cleaning is not enough filled
Point, it does not wash clean.There are the plastics or silica gel buckle of fixed sampling pin position on sampling probe, dry, cleaning should not be put into baking oven
Remaining water is easy that sampling probe is made to get rusty in sampling probe afterwards, and small rusty stain or iron filings are for the sample that is taken under 0.1M hydrochloric acid medium
Product have an impact, and there are larger differences with true value for the result measured with ultraviolet-visible photometric device.
Summary of the invention
The purpose of this utility model is to provide a kind of convenience, the equipment of high-efficiency washing, dry digestion instrument sampling probe.This sets
Standby a tractor serves several purposes, has cleaning function, functions/drying.Easy to operate quick, maintenance is simply.Cleaning efficiency is higher, can mention significantly
High efficiency of research and development shortens the R&D cycle of enterprise, while being cleaned and dried the dry sampling of instrument clean through the multifunction sampling needle
Needle is not easy to get rusty, it is ensured that the accuracy of experimental result.
Multi-functional digestion instrument sampling probe is cleaned and dried instrument, it is characterised in that it includes purge tank, sampling needle interface, air hair
Raw, heating device and waste liquid receiving device, bracket；The purge tank is cylindrical, and the purge tank top nose is equipped with
Cleaning solution feed opening, top rear pass through gas-guide tube and air generation, heating device connection；Purge tank side is regarded equipped with cleaning solution
Window；It is equipped with a row at purge tank A line and samples needle interface；Sampling probe is inserted into sampling needle interface.
The A line is to be cleaned and dried line of demarcation.
The sampling probe lower end of interface is parallel with A line or sampling probe lower end of interface is higher than A line.
Sampling needle interface is more than one.
Working principle of the utility model is: cleaning solution is held in purge tank, by air generator to the cleaning of sealing
Tank pressurization, high-pressure cleaning liquid are rinsed sampling probe, when liquid liquid level to be cleaned is lower than sampling needle interface, i.e., lower than A line in Fig. 2
(being cleaned and dried line of demarcation), high pressure gas blows out cleaning solution remaining in sampling probe, and heats drying.
Beneficial effect
1, the utility model is easy to operate, quick.Scavenging period is set, all operationss can be completed in drying time, no
Manual-cleaning is needed, the labor intensity of research staff can be greatly reduced.
2, the sampling probe of the utility model cleaning is not easy to get rusty, it is ensured that the accuracy of experimental data.
3, the utility model can clean multiple sampling probes simultaneously, and conventional digestion instrument is equipped with 12 stripping rotors and 12 at present
Sampling probe, this equipment can clean 12 sampling probes simultaneously, can dry 12 sampling probes simultaneously, and the whole series operation needs 5-10 minutes.
Detailed description of the invention
Fig. 1 is the utility model stereoscopic schematic diagram；
Fig. 2 is the utility model main portion cross-sectional face schematic diagram；
Wherein 1 is cleaning solution feed opening, and 2 be cleaning solution form, and 3 be waste liquid receiving device, and 4 be gas-guide tube, and 5 send out for air
Raw, heating device, 6 be sampling needle interface, and 7 be bracket, and 8 be purge tank, and 9 be sampling needle interface, and 10 be sampling probe, and A line is clear
Wash dry line of demarcation.
Specific embodiment
The present invention will be further illustrated below in conjunction with specific embodiments.It is practical new that these embodiments are merely to illustrate this
Type, rather than limitation the scope of the utility model.Unless otherwise defined, all professional and scientific terms as used herein with
Meaning known to one skilled in the art is identical.In addition, any method similar to or equal to what is recorded and material are all
It can be applied in the utility model method.The preferred methods and materials described herein are for illustrative purposes only.
Embodiment 1
As shown in Fig. 1 and Fig. 2, it includes purge tank 8 that multi-functional digestion instrument sampling probe, which is cleaned and dried instrument, sampling needle interface 9, sky
Gas generation, heating device 5 and waste liquid receiving device 3, bracket 7；The purge tank 8 is cylindrical, and the purge tank 8 pushes up
Portion front end is equipped with cleaning solution feed opening 1, and top rear passes through gas-guide tube 4 and air generation, 5 connection of heating device；8 side of purge tank
Face is equipped with cleaning solution form 2；It is equipped with a row at purge tank A line and samples needle interface 9；Sampling probe 10 is inserted into sampling needle interface 9
It is interior；The A line is to be cleaned and dried line of demarcation；It is parallel with A line to sample 9 lower end of needle interface, or sampling 9 lower end of needle interface is higher than A
Line, wherein sampling needle interface 9 is more than one.
Embodiment 2
X tablet (drug itself criticize in, differences between batches it is small) dissolution curve continuous mode, we compared old sampling probe A and take
Sample (3 months sampling probes are rinsed with tap) (is used described in embodiment 1 with completely new sampling probe B sampling, with old sampling probe C sampling
Multifunction sampling needle be cleaned and dried the sampling probe in instrument cleaning March), strict control experimentation guarantees in addition to sampling probe is different
Other operations are all consistent, detect (Detection wavelength 244nm) through ultraviolet-visible photometric device, measurement result is as follows:
Conclusion: X tablet is sampled by the old sampling probe through routinely cleaning, and will increase light absorption value under 244nm wavelength, to molten
Measurement impacts out, and it is irregular follow, the result that is measured with completely new sampling probe sampling and use Multifunction washing always
The result that the sampling probe sampling of drying instrument cleaning measures is close.
Embodiment 3
Have an impact to confirm sampling probe to dissolution result, we have investigated blank solution, and (dissolution for not throwing tablet is real
Test), at the same we taken liquid is filtered with the filter membrane of different-grain diameter after contrast test result.
Conclusion: taking blank medium with different old sampling probes in 0.1M hydrochloric acid medium, with conventional clear under 244nm wavelength
The old sampling probe sampling of washing method cleaning is ultraviolet absorption, and it is clear to be cleaned and dried instrument with multifunction sampling needle described in embodiment 1
The sampling probe sampling washed does not absorb (detected value ± 0.002 is instrument fluctuation, belongs to normal value).
Claims (4)
1. a kind of multi-functional digestion instrument sampling probe is cleaned and dried instrument, it is characterised in that it includes purge tank, samples needle interface, air
Generation, heating device and waste liquid receiving device, bracket；The purge tank is cylindrical, and the purge tank top nose is set
There is cleaning solution feed opening, top rear passes through gas-guide tube and air generation, heating device connection；Purge tank side is equipped with cleaning solution
Form；It is equipped with a row at the A line of purge tank and samples needle interface, sampling probe can be inserted into sampling needle interface；The branch mounts
Below purge tank.
2. a kind of multi-functional digestion instrument sampling probe according to claim 1 is cleaned and dried instrument, it is characterised in that the A line
To be cleaned and dried line of demarcation.
3. a kind of multi-functional digestion instrument sampling probe according to claim 1 is cleaned and dried instrument, it is characterised in that the sampling
Needle interface lower end is parallel with A line or sampling probe lower end of interface is higher than A line.
4. a kind of multi-functional digestion instrument sampling probe according to claim 1 is cleaned and dried instrument, it is characterised in that sampling probe connects
Mouth is 1 or more.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821491814.XU CN209310459U (en) | 2018-09-13 | 2018-09-13 | A kind of multi-functional digestion instrument sampling probe cleaning-drying instrument |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821491814.XU CN209310459U (en) | 2018-09-13 | 2018-09-13 | A kind of multi-functional digestion instrument sampling probe cleaning-drying instrument |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN209310459U true CN209310459U (en) | 2019-08-27 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201821491814.XU Active CN209310459U (en) | 2018-09-13 | 2018-09-13 | A kind of multi-functional digestion instrument sampling probe cleaning-drying instrument |
Country Status (1)
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| CN (1) | CN209310459U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112547699A (en) * | 2020-11-13 | 2021-03-26 | 苏州长光华医生物医学工程有限公司 | Avoid cleaning structure of sample needle hanging liquid |
| CN113289987A (en) * | 2021-05-11 | 2021-08-24 | 上海空间推进研究所 | Cleaning device for inner cavity of thin tube |
-
2018
- 2018-09-13 CN CN201821491814.XU patent/CN209310459U/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112547699A (en) * | 2020-11-13 | 2021-03-26 | 苏州长光华医生物医学工程有限公司 | Avoid cleaning structure of sample needle hanging liquid |
| CN113289987A (en) * | 2021-05-11 | 2021-08-24 | 上海空间推进研究所 | Cleaning device for inner cavity of thin tube |
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