CN209307380U - Improve the PCR gene amplification instrument of sample temperature consistency - Google Patents

Improve the PCR gene amplification instrument of sample temperature consistency Download PDF

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Publication number
CN209307380U
CN209307380U CN201821477409.2U CN201821477409U CN209307380U CN 209307380 U CN209307380 U CN 209307380U CN 201821477409 U CN201821477409 U CN 201821477409U CN 209307380 U CN209307380 U CN 209307380U
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scoreboard
heat dissipation
dissipation element
air
module
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CN201821477409.2U
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陈方兴
谢廉毅
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Hangzhou Beagle Flying Biology Technology Co Ltd
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Hangzhou Beagle Flying Biology Technology Co Ltd
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Abstract

The utility model discloses the PCR gene amplification instruments for improving sample temperature consistency, including shell, module, semiconductor chilling plate and heat dissipation element, semiconductor chilling plate is between module and heat dissipation element, shell is equipped with air inlet and air outlet, heat dissipation element has air part and the outlet section opposite with air part, control aerofoil is equipped with below heat dissipation element, controlling aerofoil has the first scoreboard corresponding with air part position, and the second scoreboard corresponding with outlet section position, the second scoreboard protrude from the first scoreboard.The first scoreboard is arranged by the lower section of the air part in heat dissipation element in the utility model, in the lower section of outlet section, the second scoreboard is set, second scoreboard protrudes from the first scoreboard, air quantity into inlet portion is less than the air quantity into outlet portion, keep module integral heat sink uniform, to improve the consistency of sample temperature in PCR module.

Description

Improve the PCR gene amplification instrument of sample temperature consistency
Technical field
The utility model relates to biochemistry test instruments, more specifically, it is related to improving sample temperature consistency PCR gene amplification instrument.
Background technique
PCR, the external primer of polymerase chain reaction, also known as cell-free molecular cloning or specific DNA sequences orient enzymatic Amplification technique is a kind of method of external enzyme' s catalysis specific DNA fragment, by high-temperature denaturation, low-temperature annealing and appropriate temperature extension etc. A few step reaction composition a cycles, circulation carry out, rapidly amplify target DNA, have high specificity, high sensitivity, behaviour Make the features such as easy, time saving.It cannot be only used for the basic research such as Gene Isolation, clone and nucleic acid sequence analysis, it may also be used for The diagnosis of disease any has DNA, the place of RNA.PCR thus the method immediately molecular biology, microbiology, medicine and The multi-field extensive use such as science of heredity and rapid development.
Gene-amplificative instrament has module, semiconductor chilling plate and heat dissipation element, and heat dissipation element with external wind convection current by changing Heat plays the role of cooling down to module heat dissipating.But external wind is entered from the air part of heat dissipation element, it is opposite from its The form of outlet section discharge, when initially entering heat dissipation element due to external wind, can make the module fast cooling of air part, arrived and dissipated Thermal element back segment, external wind temperature after heat convection in part is increased, unobvious to the heat dissipation effect of module back segment, is caused Entire module heat dissipating is uneven, and two sides temperature difference is obvious, and the temperature so as to cause sample in module is inconsistent.
Summary of the invention
The purpose of this utility model is to provide improve sample temperature consistency PCR gene amplification instrument, external wind from dissipate The air part of thermal element is passed through to the outlet section of its opposite side, and the air quantity of air part and outlet section is entered by controlling, makes to enter The air quantity of air part is few, and the air quantity into outlet section is more, guarantees that module integral heat sink is uniform, to improve sample in PCR module Temperature consistency.
The technical scheme adopted by the utility model to solve the technical problem is as follows: improving the PCR base of sample temperature consistency Gene-amplification instrument, including shell, module, semiconductor chilling plate and heat dissipation element, semiconductor chilling plate are located at module and heat dissipation element Between, shell is equipped with air inlet and air outlet, it is characterised in that: heat dissipation element have air part and it is opposite with air part go out Wind portion, heat dissipation element lower section are equipped with control aerofoil, and control aerofoil has the first scoreboard corresponding with air part position, and and outlet section Corresponding second scoreboard in position, the second scoreboard protrude from the first scoreboard.
External wind enters from the air part of heat dissipation element, heat dissipation element and external wind heat convection, to make module heat dissipating Cooling.Since the second scoreboard protrudes from the first scoreboard, between the first scoreboard and air part for it is distinguished and admirable enter space be greater than second Space between scoreboard and outlet section, only part air quantity enter inlet portion, and outlet portion then has a large amount of wind to enter, and inlet portion connects The fresh-air volume of touching is few, and air temperature is low;The air quantity of outlet section contact includes that part is low from the wind and temperature of inlet portion Fresh air, it is ensured that module heat dissipating is uniform, to improve the temperature consistency of sample in PCR module.Here fresh air refer to not with The external wind of heat dissipation element contact.
As a preferred option, the bottom end of the first scoreboard covering air part, the second scoreboard cover the bottom end of outlet section.
As a preferred option, control aerofoil includes third scoreboard, passes through third scoreboard between the first scoreboard and the second scoreboard Connection, third scoreboard are inclined end face.Third scoreboard is arranged to it is skewed, be conducive to wind gently collect.
As a preferred option, the second scoreboard is close to heat dissipation element bottom.Second scoreboard is close to heat dissipation element bottom, heat dissipation The air quantity of the outlet section contact of element is big, and radiating efficiency is high.
As a preferred option, heat dissipation element includes heat-conducting plate and radiator, and semiconductor chilling plate upper surface and module are pasted It closes, lower end surface is bonded with heat-conducting plate, and radiator is equipped with below heat-conducting plate;Radiator is provided with multiple grooves.Preferably, radiator For rule shape, such as cuboid, square.Preferably, groove is arranged in parallel.Preferably, groove equidistantly distributed.It is preferred that , radiator selects fin.Groove passes through for wind.
Utility model has the advantages that the first scoreboard is arranged in the lower section by the air part in heat dissipation element, in outlet air The second scoreboard is arranged in the lower section in portion, and the second scoreboard protrudes from the first scoreboard, and the air quantity into inlet portion is less than into outlet portion Air quantity keeps module integral heat sink uniform, to improve the consistency of sample temperature in PCR module.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of the utility model.
Fig. 2 is the structural schematic diagram of heat dissipation element.
Fig. 3 is the air inlet of shell and the schematic diagram of air outlet.
It is identified in figure: shell 1, air inlet 11, air outlet 12, module 2, semiconductor chilling plate 3, heat dissipation element 4, heat-conducting plate 41, radiator 42, air part 421, aerofoil 7, the first scoreboard 71, the second scoreboard 72, third scoreboard 73, groove are controlled in outlet section 422 423, protrusion 13, recess 131, foot pad 14.
Specific embodiment
The present invention will be further described below with reference to the accompanying drawings and specific embodiments.
Embodiment 1
As shown in Figure 1-3, improving the PCR gene amplification instrument of sample temperature consistency, including shell 1, module 2, semiconductor Cooling piece 3 and heat dissipation element 4, for semiconductor chilling plate 3 between module 2 and heat dissipation element 4, shell 1 is equipped with 11 He of air inlet Air outlet 12, heat dissipation element 4 have air part 421 and the outlet section 422 opposite with air part 421, set below heat dissipation element 4 There is control aerofoil 7, control aerofoil 7 has the first scoreboard 71 corresponding with 421 position of air part, and corresponding with 422 position of outlet section The second scoreboard 72, the second scoreboard 72 protrudes from the first scoreboard 71.
External wind enters from the air part 421 of heat dissipation element 4, heat dissipation element 4 and external wind heat convection, to make module 2 radiating and coolings.Since the second scoreboard 72 protrudes from the first scoreboard 71, between the first scoreboard 71 and air part 421 for it is distinguished and admirable enter Space be greater than space between the second scoreboard 72 and outlet section 422, only part air quantity enters air part 421, outlet section 422 Then there is a large amount of wind to enter, the fresh-air volume that air part 421 contacts is few, and air temperature is low;The air quantity that outlet section 422 contacts includes portion Divide the fresh air low from the wind and temperature of air part 421, it is ensured that module 2 radiates uniformly, improves sample in PCR module 2 Temperature consistency.Here fresh air refers to the external wind not contacted with heat dissipation element.
As specific embodiment, the first scoreboard 71 covers the bottom end of air part 421, and the second scoreboard 72 covers outlet section 422 bottom end.The bottom end of second scoreboard 72 covering outlet section 422 can guarantee that external wind is sufficiently contacted with outlet section 422.
As specific embodiment, controlling aerofoil 7 includes third scoreboard 73, is led between the first scoreboard 71 and the second scoreboard 72 The connection of third scoreboard 73 is crossed, third scoreboard 73 is inclined end face.Third scoreboard 73 is arranged to skewed, is conducive to the gentle of wind Collect.First scoreboard 71, third scoreboard 73 and the second scoreboard 72 are fixedly connected sequentially.
As specific embodiment, the upper surface of the second scoreboard 72 is close to 4 bottom end of heat dissipation element.Second scoreboard 72 it is upper End face is close to 4 bottom end of heat dissipation element, and the air quantity that the outlet section 422 of heat dissipation element 4 contacts is big, and radiating efficiency is high.
As shown in Fig. 2, heat dissipation element 4 includes heat-conducting plate 41 and radiator 42, semiconductor system as specific embodiment Cold 3 upper surfaces are bonded with module 2, and lower end surface is bonded with heat-conducting plate 41, and radiator 42 is equipped with below heat-conducting plate 41;Radiator 42 are provided with multiple grooves 423 passed through for wind.Preferably, radiator 42 is the shape of rule, such as cuboid, square.It is excellent Choosing, groove 423 is arranged in parallel.Preferably, 423 equidistantly distributed of groove.Preferably, radiator 42 selects fin.Module 2 Heat is conducted by semiconductor chilling plate 3 to heat-conducting plate 41, and heat-conducting plate 41 conducts heat on radiator 42 again, radiator 42 exchange heat with cross-ventilation, to cool down to module 2.
Embodiment 2
The present embodiment the difference from embodiment 1 is that: air inlet 11 is set to 1 bottom of shell, and air outlet 12 is set to shell The rear side of body 1;1 bottom margin of shell is equipped with protrusion 13, and protrusion 13 is provided with connection air inlet 11 and extraneous recess 131, described Raised 131 bottom ends are equipped with foot pad 14, referring to Fig. 3.The rear side of shell 1 refers to the side opposite with instrument display screen.
1 bottom of shell is set to using air inlet 11, air outlet 12 is set to 1 rear side of shell, air part 421 and outlet section 422 are located at the form of 4 opposite sides of heat dissipation element, and more instruments are placed side by side to do adjacent apparatuses in use, not only reducing It disturbs, and the spacing between instrument reduces, to reduce occupied space.1 bottom margin recess 131 of shell is provided with conducive to outer Boundary's wind enters instrument internal;Simultaneously 1 bottom of shell foot pad 14 is installed, make instrument be higher than holding plane, be conducive to external wind into Enter air inlet 11.
As a specific embodiment, 131 surface of recess is arc-shaped.The recess 131 of arcuate shape be conducive to wind into Enter, and facilitates portable by instrument.
As a specific embodiment, the front side of protrusion 13 and opposite sides are provided with recess 131.Protrusion 13 Front side and opposite sides refer to the front side and the left and right sides of instrument.Multiple recesses 131 are set and advantageously ensure that enough wind Amount enters.It is equipped with recess 131 in the opposite sides of protrusion 13, can not only guarantee the symmetry of shell 1, but also remove conducive to both hands Dynamic instrument.The front side of protrusion 13 refers to the direction where display screen.
As a specific embodiment, the quadrangle of raised 13 bottom ends is equipped with foot pad 14, and foot pad 14 is symmetrical arranged.? Four corners are symmetrical arranged foot pad 14, and it is steady to guarantee that instrument is placed.The height of foot pad 14 is suitable, has not only made the steadily of centre of gravity of instrument, but also It can ensure that the air quantity for entering air inlet 11 is enough, guarantee the quick temperature-reducing function of instrument.
As a specific embodiment, foot pad 14 is coated with anti-slip layer.Anti-slip layer uses the material with anti-skidding effect Material, such as rubber.
Content described in this specification embodiment is only enumerating to the way of realization of inventive concept, the utility model Protection scope should not be construed as being limited to the specific forms stated in the embodiments, and the protection scope of the utility model is also and in this Field technical staff conceive according to the present invention it is conceivable that equivalent technologies mean.

Claims (5)

1. the PCR gene amplification instrument of sample temperature consistency, including shell, module, semiconductor chilling plate and heat dissipation element are improved, Semiconductor chilling plate is between module and heat dissipation element, and shell is equipped with air inlet and air outlet, it is characterised in that: heat dissipation element With air part and the outlet section opposite with air part, control aerofoil is equipped with below heat dissipation element, control aerofoil has and air part Corresponding first scoreboard in position, and the second scoreboard corresponding with outlet section position, the second scoreboard protrude from the first scoreboard.
2. improving the PCR gene amplification instrument of sample temperature consistency as described in claim 1, it is characterised in that: the first scoreboard The bottom end of air part is covered, the second scoreboard covers the bottom end of outlet section.
3. improving the PCR gene amplification instrument of sample temperature consistency as claimed in claim 2, it is characterised in that: the second scoreboard Upper surface close to heat dissipation element bottom end.
4. improving the PCR gene amplification instrument of sample temperature consistency as claimed in claim 3, it is characterised in that: control aerofoil packet Third scoreboard is included, is connected between the first scoreboard and the second scoreboard by third scoreboard, third scoreboard is inclined end face.
5. improving the PCR gene amplification instrument of sample temperature consistency as described in claim 1, it is characterised in that: heat dissipation element Including heat-conducting plate and radiator, semiconductor chilling plate upper surface is bonded with module, and semiconductor chilling plate lower end surface and heat-conducting plate paste It closes, radiator is equipped with below heat-conducting plate;Radiator is provided with multiple grooves.
CN201821477409.2U 2018-09-11 2018-09-11 Improve the PCR gene amplification instrument of sample temperature consistency Active CN209307380U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201821477409.2U CN209307380U (en) 2018-09-11 2018-09-11 Improve the PCR gene amplification instrument of sample temperature consistency

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201821477409.2U CN209307380U (en) 2018-09-11 2018-09-11 Improve the PCR gene amplification instrument of sample temperature consistency

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113316352A (en) * 2021-01-15 2021-08-27 北京中科生仪科技有限公司 Heat dissipation structure and heat dissipation method of PCR detector

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113316352A (en) * 2021-01-15 2021-08-27 北京中科生仪科技有限公司 Heat dissipation structure and heat dissipation method of PCR detector

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